Cisplatin Treatment Options

A collection of 1441 research studies where Cisplatin is the interventional treatment. These studies are located in the United States . Cisplatin is used for conditions such as Head and Neck Cancer, Lung Cancer and Non-Small Cell Lung Cancer.

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Featured Trial

Healthy Participants Needed (Colonoscopy + Cancer Screening)

Recruiting

Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.

Conditions:

Healthy

Healthy Volunteers

Healthy Subjects

Healthy Volunteer

Healthy Participants

Learn More

Featured Offer

Lose Weight with GLP-1 Medications

Recruiting

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As a valued user, you’re eligible for $50 off your first program with code policy-lab-50.

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

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Featured Trial

Stroke Clinical Study

Recruiting

A clinical study for people that suffer with Stroke

Conditions:

Stroke

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Featured Trial

Chronic Kidney Disease (CKD) Clinical Study

Recruiting

A clinical study for people that suffer with Chronic Kidney Disease (CKD)

Conditions:

Chronic Kidney Disease (CKD)

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Hypofractionated Radiochemotherapy

NCT06331468

Recruiting

The goal of this clinical trial is to investigate the use of hypofractionated radiation (delivery of fewer but larger doses of radiation) with concurrent chemotherapy for women with metastatic of bulky uterine cervix cancer. The main questions it aims to answer are: * What is the MRI-assessed rate of response at 1-month and 3-months post-treatment? * What is the safety and tolerability of cisplatin-based hypofractionated pelvic Intensity Modulated Radiation Therapy (IMRT) followed by brachytherapy? * What is the median progression-free survival and overall survival at 1 and 2 years for patients who undergo cisplatin-based hypofractionated pelvic IMRT? * What is the proportion of patients who complete the treatment in prescribed timeframe? * What the levels of cervix cancer circulating tumor cells pretherapy and after treatment? To confirm eligibility, within four weeks prior to study enrollment, all patients will undergo the following: * Complete history and physical exam, GOG performance status evaluation * Standard of care scans, which include staging CTs and/or PET scans, and MRI to verify eligibility and appropriate stage of disease. Blood tests will be done to check various organ functions. Treatment will be administered on an outpatient basis. The main difference between the proposed regimen in the trial and standard of care is as follows: 1. The trial has a shortened course of EBRT. Standard of care utilizes 25 treatments, also known as "fractions" of EBRT, while the trial utilizes 8 fractions of EBRT. An equivalent "biological effective dose" is achieved by increasing the radiation dose per fraction. 2. The concurrent cisplatin dosing is shortened from 5-6 cycles of cisplatin to 2 cycles of cisplatin. The dose of cisplatin is 40 mg/m2. This protocol requires photon IMRT technique followed by high dose rate (HDR) brachytherapy. The therapies use focused energy beams to kill cancer cells. Radiation therapy must be completed within 30 days +/- 2 days of initiation. Computed tomography simulation with the patient in a head-first laying on back-supine position is required. MRI-guided treatment planning and image guidance during treatment for motion management will be used. IMRT will be given once daily Monday-Thursday, four fractions per week. The high-dose-rate (HDR) brachytherapy following institutional protocol. Brachytherapy will be delivered twice per week with a 2-day break in between sessions. A total of four brachytherapy treatments will be delivered. After active therapy is completed, treatment-related toxicity will be assessed at the 1-month post-treatment completion visit and again at the 3-month post-treatment completion. Patients removed from the study for unacceptable adverse events will be followed until resolution or stabilization of the adverse event(s). Routine MRI imaging to assess treatment response to radiotherapy is conducted at Day 15. Treatment response to radiotherapy followed by brachytherapy will be assessed at the 1- month and 3-months post-treatment completion. Following the 3-months post-treatment completion, study participants will be followed for disease progression and survival status until Year 2 post-treatment initiation. NOTE: Cervical cancer patients are routinely followed (clinical surveillance) every 3-months during the first two years post-treatment. Read Less

Gender:

FEMALE

Ages:

Between 18 years and 120 years

Trial Updated:

06/26/2025

Locations: Markey Cancer Center, Lexington, Kentucky

Conditions: Uterine Cervix Cancer

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UARK 2013-13, Total Therapy 4B - Formerly 2008-01 - A Phase III Trial for Low Risk Myeloma

NCT00734877

Active Not Recruiting

Toward improving the therapeutic index of standard TT3 (S-TT3), the investigators will employ a randomized Phase III trial design to determine whether S-TT3 treatment-related toxicities can be reduced by 50% in TT3-Lite (L-TT3). Note: Randomization has been discontinued and accrual is closed to the L-TT3 arm. This trial is currently enrolling as a single-arm trial for patients to receive S-TT3.

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

06/25/2025

Locations: University of Arkansas for Medical Sciences, Myeloma Institute for Research and Therapy, Little Rock, Arkansas

Conditions: Multiple Myeloma

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Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)

NCT05555732

Recruiting

This study is designed to assess the efficacy and safety of datopotamab deruxtecan (Dato-DXd) in combination with pembrolizumab versus pembrolizumab in combination with pemetrexed and platinum chemotherapy in participants with no prior therapy for advanced or metastatic non-squamous non-small cell lung cancer (NSCLC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: Southern Cancer Center Pc, Daphne, Alabama +246 locations

Southern Cancer Center Pc, Daphne, Alabama

Ironwood Cancer and Research Centers, Chandler, Arizona

Arizona Oncology Associates, Pc - Nahoa, Prescott Valley, Arizona

Hoag Memorial Hospital Prebyterian, Newport Beach, California

Compassionate Cancer Care Medical Group, Riverside, California

Sansum Clinic, Santa Barbara, California

Ronald Reagan UCLA Medical Center, Santa Monica, California

UCHealth Memorial Hospital, Colorado Springs, Colorado

Florida Cancer Specialists - South, Fort Myers, Florida

Cancer Specialist of North Florida, Jacksonville, Florida

Cancer Care Centers of Brevard, Inc., Palm Bay, Florida

Woodlands Medical Specialists, Pa, Pensacola, Florida

Florida Cancer Specialists-North, Saint Petersburg, Florida

Emory University - Winship Cancer Institute Wci, Atlanta, Georgia

Illinois Cancer Specialists, Niles, Illinois

American Oncology Partners of Maryland, Bethesda, Maryland

Maryland Oncology Heamtology P.A., Columbia, Maryland

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Dana Farber Cancer Institute; Inv Drg Svc Pharm, Boston, Massachusetts

Dana Farber Cancer Institute At St. Elizabeth'S Medical Center, Brighton, Massachusetts

Dana Farber Brigham Cancer Center, Foxboro, Massachusetts

Dana Farber At Milford Regional Cancer Center, Milford, Massachusetts

Dana Farber/Bwcc in Affiliation With South Shore Hospital, South Weymouth, Massachusetts

Astera Cancer Care, East Brunswick, New Jersey

Regional Cancer Care Associates LLC, Hackensack, New Jersey

North Shore Hematology Oncology Associates dba NY Cancer and Blood Specialists - Bronx, Bronx, New York

North Shore Hematology Oncology Associates dba NY Cancer and Blood Specialists- New Hyde Park, New Hyde Park, New York

North Shore Hematology Oncology Associates, Patchogue, New York

North Shore Hematology Oncology Associates DBA NY Cancer and Blood Specialists, Port Jefferson Station, New York

Texas Oncology, P.A., McAllen, Texas

Ut Health San Antonio, San Antonio, Texas

Texas Oncology, P.A., Sugar Land, Texas

Texas Oncology-Tyler, Tyler, Texas

Utah Cancer Specialists IHO Corp, Salt Lake City, Utah

Providence Regional Cancer System, Lacey, Washington

VA Puget Sound Health Care System, Seattle, Washington

Instituto Alexander Fleming, Ciudad Autonoma de Buenos Aires, Not set

Fundacion CENIT para la investigacion en Neurociencias, Ciudad Autonoma de Buenos Aire, Not set

Hospital de La Comunidad, Mar del Plata, Not set

Centro de Investigacion Pergamino Sa, Pergamino, Not set

Instituto de Oncologia de Rosario, Rosario, Not set

Sanatorio Parque, Rosario, Not set

Centro Polivalente de Asistencia E Investigacion Clinica Cer San Juan, San Juan, Not set

Centro de Investigaciones Clinicas. Clinica Viedma S.A., Viedma, Not set

CRSA/ St Andrews Hospital, Adelaide, Not set

Flinders Medical Centre (Fmc), Bedford Park, Not set

PSEHOG (Peninsula and South Eastern Haematology and Oncology Group), Frankston, Not set

St George Public Hospital, Kogarah, Not set

Southern Medical Day Care Centre, Wollongong, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

Landeskrankenhaus Feldkirch, Feldkirch, Not set

Klinikum Klagenfurt Pulmologie, Klagenfurt, Not set

Karl Landsteiner Institut Fã¼R Lungenforschung Und Pneumologische Onkologie C/O Klinik Floridsdorf, Vienna, Not set

Az Maria Middelares - Campus Maria Middelares, Gent, Not set

Centre hospitalier Jolimont-Lobbes, Haine Saint-Paul, Not set

Jessa Hospital, Hasselt, Not set

Cliniques Saint Pierre Ottignies (CSPO), Ottignies, Not set

Az Nikolaas, Sint-Niklaas, Not set

Personal Oncologia de Precisao - Cenantron, Belo Horizonte, Not set

Fundaco Universidade de Caxias Do Sul- Instituto de Pesquisas Em Saude Ips-Ucs, Caxias do Sul, Not set

Hospital Erasto Gaertner, Curitiba, Not set

Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda, Ijui, Not set

Clínica de Neoplasias Litoral Ltda, ItajaĂ-, Not set

Clnica Lacks, Pelotas, Not set

Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Not set

Instituto Nacional de Că'Ncer - Inca, Rio de Janeiro, Not set

Centro de Estudos E Pesquisa de Hematologia E Oncologia - Cepho, Santo Andre, Not set

Instituto de Ensino E Pesquisa Sao Lucas, Sao Paulo, Not set

Instituto Do Cancer Brasil - Unidade Taubate, Taubate, Not set

CHU de Quebec -Universite Laval Hopital de L'Enfant-Jesus, Quebec City, Not set

Centro de Estudios Clinicos Saga Spa, Santiago de Chile, Not set

ONCOVIDA, Santiago, Not set

Orlandi Oncologia, Santiago, Not set

Oncocentro Apys, Vina Del Mar, Not set

Centro de Investigaciones Clinicas Vina Del Mar, ViĂąa Del Mar, Not set

Peking University Cancer Hospital Beijing Cancer Hospital Beijing Institute For Cancer Research, Beijing Sheng, Not set

Peking University Peoples Hospital, Beijing, Not set

Cangzhou Peoples Hospital, Cangzhou, Not set

First Affiliated Hospital of Medical College of Jilin University, Changchun, Not set

Jilin Cancer Hospital, Changchun, Not set

Hunan Cancer Hospital, Changsha, Not set

University of Electronic Science Technology of China UESTC - Sichuan Cancer Hospital Institute SIC, Chengdu, Not set

Chongqing University Cancer Hospital, Chongqing, Not set

Fujian Medical University - Union Hospital Foochow Christian Union Hospital, Fuzhou, Not set

The First Affiliated Hospital Sun Yat-Sen University, Guangzhou, Not set

Affiliated Cancer Hospital and Insititute of Guangzhou Medical University, Guangzhou, Not set

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Not set

Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Not set

The First Affiliated Hospital of College of Medicine Zhejiang University, Hangzhou, Not set

Harbin Medical University Cancer Hospital, Harbin, Not set

Inner Mongolia Medical University- the Affiliated Hospital, Hohhot, Not set

Jiamusi Cancer Hospital, Jiamusi, Not set

Linyi Cancer Hospital, Linyi, Not set

The First Affiliated Hospital of Nanchang University, Nanchang, Not set

Zhongda Hospital, Southeast University, Nanjing, Not set

Shanghai Chest Hospital, Shanghai, Not set

Fudan University Shanghai Cancer Center, Shanghai, Not set

Liaoning Cancer Hospital & Institute, Shenyang, Not set

Union Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan, Not set

The First Affiliate Hospital of Xi'An Jiaotong University, Xi'an, Not set

Xiangyang Central Hospital, Xianyang, Not set

Henan Cancer Hospital, Zhengzhou, Not set

The First Affiliated Hosptial of Xinjiang Medical University, Ürümqi, Not set

FN Brno Klinika Nemoci Plicnich a TBC, Brno, Not set

Fakultni nemocnice Olomouc FNOL, Olomouc, Not set

Sainte-Catherine Institut du Cancer Avignon-Provence, Avignon, Not set

Hopital Jean Minjoz - CHU de Besancon, Besancon, Not set

Chu de Bordeaux - Hopital Saint Andre, Bordeaux, Not set

Centre Hospitalier Universitaire, CHU, de Poitiers, France, Not set

Hopital Lyon Sud, Lyon, Not set

Centre Leon Berard, Lyon, Not set

Aphm - Hopital Nord, Marseille Cedex 20, Not set

Institut Paoli Calmettes, Marseille, Not set

Chu de Montpellier, Montpellier Cedex 5, Not set

Chu de Nantes, Nantes, Not set

Hopital Prive Du Confluent, Nantes, Not set

Institut Curie, Paris Cedex 05, Not set

Tenon Hospital, Paris, Not set

CHU de Rennes - Hopital Pontchaillou, Rennes, Not set

Hôpital Foch, Suresnes, Not set

Evangelische Lungenklinik Berlin, Berlin, Not set

Klinikum Chemnitz, Chemnitz, Not set

Universitaetsklinikum Essen, Essen, Not set

Klinikum Esslingen Gmbh, Esslingen, Not set

Universitaetsklinikum Freiburg, Freiburg, Not set

University Hospital Giessen, ZIM IV, Giessen, Not set

External pharmacy Fortuna Herstellung GmbH of main site Universitaetsmedizin Mannheim, Mannheim, Not set

University Hospital Mă Nster, Muenster, Not set

Ludwig-Maximilians University Hospital of Munich, Munich, Not set

Sotiria General Hospital of Chest Diseases, Athens, Not set

Metropolitan Hospital - Athens, Athens, Not set

University General Hospital of Heraklion, Heraklion, Not set

University Hospital of Ioannina Uhi, Ioannina, Not set

Metropolitan Hospital, Neo Faliro, Not set

Olympion Hospital, Patras, Not set

Euromedica General Clinic of Thessaloniki, Thessaloniki, Not set

St. Luke's Hospital, Thessaloniki, Not set

Bioclinic Thessaloniki (Galinos Clinic), Thessalonki, Not set

Tuen Mun Hospital, Hong Kong, Not set

Prince of Wales Hospital / The Chinese University of Hong Kong, Hong Kong, Not set

Queen Mary Hospital, Pok Fu Lam, Not set

National Koranyi Institute For Pulmonology, Budapest, Not set

Veszprem Megyei Tudogyogyintezet Farkasgyepu, Farkasgyepu, Not set

Bkmk Hospital, KecskemĂŠt, Not set

Fejer Megyei Szent Gyorgy Korhaz Pulmonologiai Osztaly, Szekesfehervar, Not set

Hetenyi G Korhaz, Onkologiai Kozpont, Szolnok, Not set

Reformatus Pulmonologiai Centrum, Torokbalint, Not set

Istituto Di Candiolo Irccs, Candiolo, Not set

Ospedale San Luca, Lucca, Not set

Azienda Ospedaliero - Universitaria San Luigi Gonzaga, Orbassano, Not set

IFO Regina Elena, Rome, Not set

Ospedale S. Maria Della Misericordia, Udine, Not set

Asst Sette Laghi, Varese, Not set

Azienda Ospedaliera Universitaria Integrata Verona Ospedale Borgo Roma Crc - Centro Ricerche Clinich, Verona, Not set

NHO Shikoku Cancer Center, Ehime, Not set

Kurume University Hospital, Fukoka, Not set

Kyushu Cancer Center, Fukuoka, Not set

Kyushu University Hospital, Fukuoka, Not set

Teine Keijinkai Hospital, Hokkaido, Not set

Hyogo Medical University Hospital, Hyogo, Not set

Kanazawa University Hospital, Ishikawa, Not set

Kanagawa Cancer Center, Kanagawa, Not set

Kitasato University hospital, Kanagawa, Not set

Social Welfare Organization Saiseikai Imperial Gift Foundation, Inc. Saiseikai Kumamoto Hospital, Kumamoto, Not set

University Hospital Kyoto Prefectual University of Medicine, Kyoto, Not set

Matsusaka Municipal Hospital, Mie, Not set

Sendai Kousei Hospital, Miyagi, Not set

Niigata Cancer Center Hospital, Niigata, Not set

Osaka International Cancer Institute, Osaka, Not set

Osaka Toneyama Medical Center, Osaka, Not set

Kansai Medical University Hospital, Osaka, Not set

NHO Kinki-Chuo Chest Medical Center, Osaka, Not set

Dokkyo Medical University Hospital, Tochigi, Not set

Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Not set

Juntendo University Hospital, Tokyo, Not set

The Cancer Institute Hospital of JFCR, Tokyo, Not set

Toho University Omori Medical Center, Tokyo, Not set

Iwakuni Clinical Center, Yamaguchi, Not set

Yamaguchi-Ube Medical Center, Yamaguchi, Not set

Yamanashi Prefectural Central Hospital, Yamanashi, Not set

Chungbuk National University Hospital, Cheongjusi, Not set

Kyungpook National University Chilgok Hospital, Daegu, Not set

Samsung Medical Center, Gangnam-Gu, Not set

National Cancer Center, Goyang-si, Not set

Gyeongsang National University Hospital, Jinju-si Gyeongsangnam-do, Not set

Seoul National University Bundang Hospital, Seongnam-si, Not set

Asan Medical Center, Seoul, Not set

Yonsei University Health System - Severance Hospital, Seoul, Not set

The Catholic Univ. of Korea, Seoul St. Marys Hospital, Seoul, Not set

Cryptex Investigacion Clinica Sa de Cv, Cuauhtemoc, Not set

Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Not set

Instituto Nacional de Cancerologia, Mexico City, Not set

Centro de Investigacion Clinica de Oaxaca CICLO, Oaxaca, Not set

Amphia Ziekenhuis, Breda, Not set

Leiden University Medical Center, Leiden, Not set

Jeroen Bosch Ziekenhuis Jbz, s-Hertogenbosch, Not set

II Klinika Chorob Pluc i Gruzlicy, Bialystok, Not set

Centrum Terapii Wspolczesnej, Lodz, Not set

Instytut Centrum Zdrowia Matki Polki (Iczmp), Lodz, Not set

SPSK4, Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin, Not set

Med Polonia Sp. Z O.O., Poznan, Not set

Maria Sklodowska-Curie National Research Institute of Oncology, Warszawa, Not set

Fundacao Champalimaud, Lisbon, Not set

IPO Porto Francisco Gentil, E.P.E., Porto, Not set

Institute of Oncology Prof. Dr. Ion Chiricuta, Cluj- Napoca, Not set

Onco Clinic Consult Sa, Craiova, Not set

Centrul de Oncologie Sfantu Nectarie, Craiova, Not set

SC Oncomed SRL, Jud Timis, Not set

Oncocenter Oncologie Clinica S.R.L, Timisoara, Not set

Vall Hebron University Hospital, Barcelona, Not set

Hospital Clinic I Provincial de Barcelona, Barcelona, Not set

Hospital Universitario Arnau de Vilanova, Lleida, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Hospital Clinico San Carlos, Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Regional Universitario Malaga, Malaga, Not set

CHUO, Ourense, Not set

Hosp Univ Virgen Macarena, Sevilla, Not set

Hospital Universitario Virgen de Valme, Sevilla, Not set

Hospital Universitario y Politecnico de La Fe, Valenica, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Kantonsspital Baselland, Liestal, Not set

Kantonsspital St. Gallen, St. Gallen, Not set

Spital Sts Ag, Thun, Not set

Changhua Christian Hospital, Changhua, Not set

China Medical University Hospital, Hsia, Not set

Taichung Veterans General Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Tri-Service General Hospital, Taipei, Not set

Linkou Chang Gung Memorial Hospital, Taoyuan, Not set

Faculty of Medicine Chulalongkorn University, Bangkok, Not set

Ramathibodi Hospital, Bangkok, Not set

Siriraj Hospital, Bangkok, Not set

Chiang Mai University CMU - Maharaj Nakhon Chiang Mai Hospital Nakorn Chiang Mai Hospital, Chiang Mai, Not set

Prince of Songkla University PSU - Faculty of Medicine, Hat Yai, Not set

Khon Kaen University - Faculty of Medicine-Srinagarind Hospital, Mueang Nonthaburi, Not set

Baskent University, Adana, Not set

Ankara Bilkent City Hospital, Ankara, Not set

Akdeniz University Hospital, Antalya, Not set

Medipol Mega University Hospital, Bağcılar, Not set

Memorial Ankara Hospital, Cankaya/Ankara, Not set

Istanbul Medeniyet University Medical Faculty, Istanbul, Not set

Adana Acibadem Hospital, Seyhan, Not set

Barts Health NHS Trust, London, Not set

Conditions: Metastatic Non Small Cell Lung Cancer

Learn More ›

OSI-774/Cisplatin/Taxotere in Head & Neck Squamous Cell Cancer

NCT00076310

Active Not Recruiting

The goal of this clinical research study is to learn if giving the new drug, Tarceva® (OSI-774), in combination with Platinol® (cisplatin) and Taxotere® (docetaxel) is effective in the treatment of metastatic or recurrent head and neck cancer. The safety of this treatment will also be studied.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: MD Anderson Cancer Center, Houston, Texas

Conditions: Head and Neck Cancer

Learn More ›

Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer

NCT05312671

Recruiting

This is a single arm, Phase II trial involving the use of atezolizumab plus platinum and etoposide for patients with locally advanced urothelial cancer. The primary goal of this trial is to assess the pathologic complete response rate at cystectomy in patients after being treated with a combination therapy of atezolizumab, platinum, and etoposide.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: Johns Hopkins University: Sibley Memorial Hospital, Washington, District of Columbia +1 locations

Conditions: Small Cell Neuroendocrine Carcinoma of Bladder, Bladder Cancer, Urothelial Carcinoma Bladder

Learn More ›

UARK 2008-02 A Trial for High-risk Myeloma Evaluating Accelerating and Sustaining Complete Remission

NCT00869232

Active Not Recruiting

There have been four previous Total Therapy (TT1 through IIIB) studies for multiple myeloma at the MIRT from 1989 to present. Results have shown that participants treated on these studies had better outcomes (meaning they have lived longer and had better responses to treatment) when compared to individuals treated with standard chemotherapy. Past studies conducted at the MIRT and at other institutions have shown that participants with high-risk features by gene array studies tend to have shorte... Read More

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

06/25/2025

Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas

Conditions: Multiple Myeloma

Learn More ›

Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

NCT04521686

Active Not Recruiting

This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitrate dehydrogenase 1 (IDH1) arginine 132 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, and glioma or isocitrate dehydrogenase 2 (IDH2) arginine 140 (R140) or arginine 172 (R172) mutant cholangiocarcinoma.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: Mayo Clinic of Scottsdale, Phoenix, Arizona +32 locations

Mayo Clinic of Scottsdale, Phoenix, Arizona

The University of Arizona Cancer Center, Tucson, Arizona

USC Norris Cancer Hospital, Los Angeles, California

Mayo Clinic in Florida, Jacksonville, Florida

University of Chicago Pritzker School of Medicine, Chicago, Illinois

Indiana University School of Medicine, Indianapolis, Indiana

The John Hopkins Hospital, Baltimore, Maryland

Massachusetts General Hospital, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Mayo Clinic, Rochester, Minnesota

Memorial Sloan Kettering Cancer Center, Middletown, New Jersey

Memorial Sloan Kettering Cancer Center, Commack, New York

Memorial Sloan Kettering Cancer Center, Harrison, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Sarah Cannon Cancer Center, Nashville, Tennessee

University of Texas MD Anderson Cancer Center, Houston, Texas

South Texas Accelerated Research Therapeutics, LLC, San Antonio, Texas

St Vincent's Hospital Sydney, Darlinghurst, New South Wales

Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest, Bordeaux, Not set

Gustave Roussy, Villejuif Cedex, Not set

Prince of Wales Hospital, Hong Kong, Shatin, New Territories

National Cancer Center Hospital East, Kashiwa, Chiba

Kanagawa Cancer Center, Yokohama, Kanagawa

Osaka University Hospital, Suita-shi, Osaka

Shizuoka Cancer Center, Nagaizumi, Shizuoka

National Cancer Center Hospital, Chuo-ku, Tokyo

Samsung Medical Center, Seoul, Seoul-teukbyeolsi [Seoul]

Seoul National University Hospital, Seoul, Not set

National University Hospital, Singapore, Not set

Hospital Universitario Vall d'Hebron, Barcelona, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

China Medical University Hospital, Taichung City, Not set

National Cheng-Kung Uni. Hosp., Tainan, Not set

Conditions: Cholangiocarcinoma, Chondrosarcoma, Glioma, Any Solid Tumor

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Toripalimab With Chemotherapy for Sinus Cancer

NCT06940180

Recruiting

The aim of this research study is to evaluate the effectiveness and safety of a combination of immunotherapy, using a drug called toripalimab, with chemotherapy drugs, Carboplatin and Docetaxel, as a possible treatment before surgery for sinonasal cancers. The names of the study drugs used in this research study are: * Toripalimab (a type of monoclonal antibody) * Carboplatin (a type of antineoplastic agent) * Docetaxel (a type of antineoplastic agent) * Cisplatin (a type of antineoplastic age... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: Brigham and Women's Hospital, Boston, Massachusetts +1 locations

Conditions: Sinonasal Cancer, Paranasal Sinus Neoplasms, Squamous Cell Carcinoma, Sinonasal Undifferentiated Carcinoma, Locally Advanced Head and Neck Cancer

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A Study of Nivolumab and Chemotherapy Followed by Surgery for Mesothelioma

NCT04162015

Active Not Recruiting

This study will test whether giving nivolumab in combination with pemetrexed and either cisplatin or carboplatin before surgery is a safe and effective approach to treating resectable mesothelioma without delaying surgery.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/24/2025

Locations: Memoiral Sloan Kettering Basking Ridge, Basking Ridge, New Jersey +6 locations

Conditions: Malignant Pleural Mesothelioma

Learn More ›

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

NCT03609216

Recruiting

This phase II trial studies how well gemcitabine hydrochloride and cisplatin work in treating participants with invasive bladder urothelial cancer. Drugs used in chemotherapy, such as gemcitabine hydrochloride and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/24/2025

Locations: Fairbanks Memorial Hospital, Fairbanks, Alaska +419 locations

Fairbanks Memorial Hospital, Fairbanks, Alaska

CTCA at Western Regional Medical Center, Goodyear, Arizona

Cancer Center at Saint Joseph's, Phoenix, Arizona

Mercy Hospital Fort Smith, Fort Smith, Arkansas

CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande, California

Mercy Cancer Center - Carmichael, Carmichael, California

Mercy San Juan Medical Center, Carmichael, California

Mercy Cancer Center - Elk Grove, Elk Grove, California

Cedars Sinai Medical Center, Los Angeles, California

Contra Costa Regional Medical Center, Martinez, California

Fremont - Rideout Cancer Center, Marysville, California

Mercy Cancer Center, Merced, California

Mercy Cancer Center - Rocklin, Rocklin, California

Mercy Cancer Center - Sacramento, Sacramento, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Pacific Central Coast Health Center-San Luis Obispo, San Luis Obispo, California

Mission Hope Medical Oncology - Santa Maria, Santa Maria, California

Saint Joseph's Medical Center, Stockton, California

BASS Medical Group - Lennon, Walnut Creek, California

Woodland Memorial Hospital, Woodland, California

Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado

The Medical Center of Aurora, Aurora, Colorado

Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado

Penrose-Saint Francis Healthcare, Colorado Springs, Colorado

Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado

Saint Francis Cancer Center, Colorado Springs, Colorado

AdventHealth Porter, Denver, Colorado

Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado

Mercy Medical Center, Durango, Colorado

Southwest Oncology PC, Durango, Colorado

Mountain Blue Cancer Care Center - Swedish, Englewood, Colorado

Swedish Medical Center, Englewood, Colorado

The Melanoma and Skin Cancer Institute, Englewood, Colorado

Mountain Blue Cancer Care Center, Golden, Colorado

Banner North Colorado Medical Center, Greeley, Colorado

Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado

Saint Anthony Hospital, Lakewood, Colorado

Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado

AdventHealth Littleton, Littleton, Colorado

Sky Ridge Medical Center, Lone Tree, Colorado

Longmont United Hospital, Longmont, Colorado

Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado

Banner McKee Medical Center, Loveland, Colorado

AdventHealth Parker, Parker, Colorado

Rocky Mountain Cancer Centers-Parker, Parker, Colorado

Saint Mary Corwin Medical Center, Pueblo, Colorado

Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado

Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado

Saint Anthony North Hospital, Westminster, Colorado

Hartford Hospital, Hartford, Connecticut

Midstate Medical Center, Meriden, Connecticut

The Hospital of Central Connecticut, New Britain, Connecticut

Holy Cross Hospital, Fort Lauderdale, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho

Walter Knox Memorial Hospital, Emmett, Idaho

Idaho Urologic Institute-Meridian, Meridian, Idaho

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho

Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho

OSF Saint Anthony's Health Center, Alton, Illinois

Rush - Copley Medical Center, Aurora, Illinois

Illinois CancerCare-Bloomington, Bloomington, Illinois

Illinois CancerCare-Canton, Canton, Illinois

Memorial Hospital of Carbondale, Carbondale, Illinois

SIH Cancer Institute, Carterville, Illinois

Illinois CancerCare-Carthage, Carthage, Illinois

Centralia Oncology Clinic, Centralia, Illinois

Saint Mary's Hospital, Centralia, Illinois

University of Illinois, Chicago, Illinois

Carle at The Riverfront, Danville, Illinois

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Illinois CancerCare-Dixon, Dixon, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Illinois CancerCare-Eureka, Eureka, Illinois

Illinois CancerCare-Galesburg, Galesburg, Illinois

Western Illinois Cancer Treatment Center, Galesburg, Illinois

Ingalls Memorial Hospital, Harvey, Illinois

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois

Illinois CancerCare-Macomb, Macomb, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

SSM Health Good Samaritan, Mount Vernon, Illinois

Cancer Care Center of O'Fallon, O'Fallon, Illinois

HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois

Illinois CancerCare-Pekin, Pekin, Illinois

OSF Saint Francis Radiation Oncology at Pekin, Pekin, Illinois

Illinois CancerCare-Peoria, Peoria, Illinois

OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois

Methodist Medical Center of Illinois, Peoria, Illinois

OSF Saint Francis Medical Center, Peoria, Illinois

Illinois CancerCare-Peru, Peru, Illinois

Valley Radiation Oncology, Peru, Illinois

Illinois CancerCare-Princeton, Princeton, Illinois

UW Health Carbone Cancer Center Rockford, Rockford, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Springfield Clinic, Springfield, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Southwest Illinois Health Services LLP, Swansea, Illinois

Carle Cancer Center, Urbana, Illinois

The Carle Foundation Hospital, Urbana, Illinois

Illinois CancerCare - Washington, Washington, Illinois

Reid Health, Richmond, Indiana

Saint Anthony Regional Hospital, Carroll, Iowa

Mercy Cancer Center-West Lakes, Clive, Iowa

UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa

Alegent Health Mercy Hospital, Council Bluffs, Iowa

Greater Regional Medical Center, Creston, Iowa

Iowa Methodist Medical Center, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa

Broadlawns Medical Center, Des Moines, Iowa

Mercy Medical Center - Des Moines, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa

Iowa Lutheran Hospital, Des Moines, Iowa

Trinity Regional Medical Center, Fort Dodge, Iowa

Methodist West Hospital, West Des Moines, Iowa

Mercy Medical Center-West Lakes, West Des Moines, Iowa

Central Care Cancer Center - Garden City, Garden City, Kansas

Central Care Cancer Center - Great Bend, Great Bend, Kansas

University of Kansas Cancer Center, Kansas City, Kansas

University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas

Flaget Memorial Hospital, Bardstown, Kentucky

Commonwealth Cancer Center-Corbin, Corbin, Kentucky

Saint Joseph Hospital, Lexington, Kentucky

Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky

Saint Joseph Hospital East, Lexington, Kentucky

Saint Joseph London, London, Kentucky

Jewish Hospital, Louisville, Kentucky

Saints Mary and Elizabeth Hospital, Louisville, Kentucky

UofL Health Medical Center Northeast, Louisville, Kentucky

Jewish Hospital Medical Center South, Shepherdsville, Kentucky

LSU Health Baton Rouge-North Clinic, Baton Rouge, Louisiana

Our Lady of the Lake Physician Group, Baton Rouge, Louisiana

Our Lady of The Lake, Baton Rouge, Louisiana

Louisiana Hematology Oncology Associates LLC, Baton Rouge, Louisiana

Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana

Northshore Oncology Associates-Covington, Covington, Louisiana

Terrebonne General Medical Center, Houma, Louisiana

Mary Bird Perkins Cancer Center - Metairie, Metairie, Louisiana

East Jefferson General Hospital, Metairie, Louisiana

LSU Healthcare Network / Metairie Multi-Specialty Clinic, Metairie, Louisiana

Louisiana State University Health Science Center, New Orleans, Louisiana

University Medical Center New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Maryland Proton Treatment Center, Baltimore, Maryland

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland

Central Maryland Radiation Oncology in Howard County, Columbia, Maryland

UM Baltimore Washington Medical Center/Tate Cancer Center, Glen Burnie, Maryland

Mercy Medical Center, Springfield, Massachusetts

Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan

Trinity Health Medical Center - Brighton, Brighton, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan

Trinity Health Medical Center - Canton, Canton, Michigan

Caro Cancer Center, Caro, Michigan

Chelsea Hospital, Chelsea, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan

Hematology Oncology Consultants-Clarkston, Clarkston, Michigan

Newland Medical Associates-Clarkston, Clarkston, Michigan

Henry Ford Health Saint John Hospital, Detroit, Michigan

Henry Ford River District Hospital, East China Township, Michigan

Cancer Hematology Centers - Flint, Flint, Michigan

Genesee Hematology Oncology PC, Flint, Michigan

Genesys Hurley Cancer Institute, Flint, Michigan

Hurley Medical Center, Flint, Michigan

Henry Ford Saint John Hospital - Academic, Grosse Pointe Woods, Michigan

Henry Ford Saint John Hospital - Breast, Grosse Pointe Woods, Michigan

Henry Ford Saint John Hospital - Van Elslander, Grosse Pointe Woods, Michigan

University of Michigan Health - Sparrow Lansing, Lansing, Michigan

Hope Cancer Clinic, Livonia, Michigan

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan

Henry Ford Saint John Hospital - Macomb Medical, Macomb, Michigan

Henry Ford Warren Hospital - Breast Macomb, Macomb, Michigan

Saint Mary's Oncology/Hematology Associates of Marlette, Marlette, Michigan

MyMichigan Medical Center Midland, Midland, Michigan

Hope Cancer Center, Pontiac, Michigan

Michigan Healthcare Professionals Pontiac, Pontiac, Michigan

Newland Medical Associates-Pontiac, Pontiac, Michigan

Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan

Henry Ford Rochester Hospital, Rochester Hills, Michigan

MyMichigan Medical Center Saginaw, Saginaw, Michigan

Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan

Bhadresh Nayak MD PC-Sterling Heights, Sterling Heights, Michigan

MyMichigan Medical Center Tawas, Tawas City, Michigan

Advanced Breast Care Center PLLC, Warren, Michigan

Henry Ford Health Warren Hospital, Warren, Michigan

Henry Ford Madison Heights Hospital - Breast, Warren, Michigan

Henry Ford Warren Hospital - GLCMS, Warren, Michigan

Macomb Hematology Oncology PC, Warren, Michigan

Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan

Huron Gastroenterology PC, Ypsilanti, Michigan

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan

Sanford Joe Lueken Cancer Center, Bemidji, Minnesota

Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota

Fairview Ridges Hospital, Burnsville, Minnesota

Minnesota Oncology - Burnsville, Burnsville, Minnesota

Mercy Hospital, Coon Rapids, Minnesota

Essentia Health - Deer River Clinic, Deer River, Minnesota

Essentia Health Saint Mary's - Detroit Lakes Clinic, Detroit Lakes, Minnesota

Essentia Health Cancer Center, Duluth, Minnesota

Essentia Health Saint Mary's Medical Center, Duluth, Minnesota

Miller-Dwan Hospital, Duluth, Minnesota

Fairview Southdale Hospital, Edina, Minnesota

Lake Region Healthcare Corporation-Cancer Care, Fergus Falls, Minnesota

Essentia Health - Fosston, Fosston, Minnesota

Unity Hospital, Fridley, Minnesota

Essentia Health Hibbing Clinic, Hibbing, Minnesota

Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota

Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota

Saint John's Hospital - Healtheast, Maplewood, Minnesota

Abbott-Northwestern Hospital, Minneapolis, Minnesota

Hennepin County Medical Center, Minneapolis, Minnesota

Health Partners Inc, Minneapolis, Minnesota

Monticello Cancer Center, Monticello, Minnesota

New Ulm Medical Center, New Ulm, Minnesota

Essentia Health - Park Rapids, Park Rapids, Minnesota

North Memorial Medical Health Center, Robbinsdale, Minnesota

Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota

Regions Hospital, Saint Paul, Minnesota

United Hospital, Saint Paul, Minnesota

Essentia Health Sandstone, Sandstone, Minnesota

Saint Francis Regional Medical Center, Shakopee, Minnesota

Lakeview Hospital, Stillwater, Minnesota

Sanford Thief River Falls Medical Center, Thief River Falls, Minnesota

Essentia Health Virginia Clinic, Virginia, Minnesota

Ridgeview Medical Center, Waconia, Minnesota

Rice Memorial Hospital, Willmar, Minnesota

Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota

Sanford Cancer Center Worthington, Worthington, Minnesota

Fairview Lakes Medical Center, Wyoming, Minnesota

Saint Louis Cancer and Breast Institute-Ballwin, Ballwin, Missouri

Central Care Cancer Center - Bolivar, Bolivar, Missouri

Parkland Health Center-Bonne Terre, Bonne Terre, Missouri

Mercy Cancer Center - Cape Girardeau, Cape Girardeau, Missouri

Saint Francis Medical Center, Cape Girardeau, Missouri

MU Health - University Hospital/Ellis Fischel Cancer Center, Columbia, Missouri

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri

Parkland Health Center - Farmington, Farmington, Missouri

MU Health Care Goldschmidt Cancer Center, Jefferson City, Missouri

Freeman Health System, Joplin, Missouri

Mercy Hospital Joplin, Joplin, Missouri

Lake Regional Hospital, Osage Beach, Missouri

Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri

Phelps Health Delbert Day Cancer Institute, Rolla, Missouri

Heartland Regional Medical Center, Saint Joseph, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital South, Saint Louis, Missouri

Siteman Cancer Center-South County, Saint Louis, Missouri

Missouri Baptist Medical Center, Saint Louis, Missouri

Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri

Mercy Hospital Springfield, Springfield, Missouri

CoxHealth South Hospital, Springfield, Missouri

Missouri Baptist Sullivan Hospital, Sullivan, Missouri

BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri

Community Hospital of Anaconda, Anaconda, Montana

Billings Clinic Cancer Center, Billings, Montana

Bozeman Health Deaconess Hospital, Bozeman, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Great Falls Clinic, Great Falls, Montana

Hi-Line Sletten Cancer Center, Havre, Montana

Saint Peter's Community Hospital, Helena, Montana

Logan Health Medical Center, Kalispell, Montana

Community Medical Center, Missoula, Montana

Nebraska Cancer Specialists/Oncology Hematology West PC, Grand Island, Nebraska

Fred and Pamela Buffett Cancer Center - Kearney, Kearney, Nebraska

CHI Health Good Samaritan, Kearney, Nebraska

Saint Elizabeth Regional Medical Center, Lincoln, Nebraska

Alegent Health Immanuel Medical Center, Omaha, Nebraska

Hematology and Oncology Consultants PC, Omaha, Nebraska

Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska

Alegent Health Lakeside Hospital, Omaha, Nebraska

Creighton University Medical Center, Omaha, Nebraska

Midlands Community Hospital, Papillion, Nebraska

Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey

Englewood Hospital and Medical Center, Englewood, New Jersey

Memorial Sloan Kettering Monmouth, Middletown, New Jersey

Memorial Sloan Kettering Bergen, Montvale, New Jersey

Roswell Park Cancer Institute, Buffalo, New York

Memorial Sloan Kettering Commack, Commack, New York

Memorial Sloan Kettering Westchester, Harrison, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

NYP/Weill Cornell Medical Center, New York, New York

Upstate Cancer Center at Oswego, Oswego, New York

University of Rochester, Rochester, New York

State University of New York Upstate Medical University, Syracuse, New York

Memorial Sloan Kettering Nassau, Uniondale, New York

Upstate Cancer Center at Verona, Verona, New York

Southeastern Medical Oncology Center-Clinton, Clinton, North Carolina

Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina

Wayne Memorial Hospital, Goldsboro, North Carolina

Onslow Memorial Hospital, Jacksonville, North Carolina

Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina

Sanford Bismarck Medical Center, Bismarck, North Dakota

Essentia Health Cancer Center-South University Clinic, Fargo, North Dakota

Sanford South University Medical Center, Fargo, North Dakota

Sanford Medical Center Fargo, Fargo, North Dakota

Sanford Broadway Medical Center, Fargo, North Dakota

Sanford Roger Maris Cancer Center, Fargo, North Dakota

Essentia Health - Jamestown Clinic, Jamestown, North Dakota

Indu and Raj Soin Medical Center, Beavercreek, Ohio

Saint Elizabeth Boardman Hospital, Boardman, Ohio

Dayton Physicians LLC-Miami Valley South, Centerville, Ohio

Miami Valley Hospital South, Centerville, Ohio

Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio

Oncology Hematology Care Inc-Kenwood, Cincinnati, Ohio

Bethesda North Hospital, Cincinnati, Ohio

TriHealth Cancer Institute-Westside, Cincinnati, Ohio

TriHealth Cancer Institute-Anderson, Cincinnati, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

Good Samaritan Hospital - Dayton, Dayton, Ohio

Miami Valley Hospital, Dayton, Ohio

Premier Blood and Cancer Center, Dayton, Ohio

Dayton Physician LLC - Englewood, Dayton, Ohio

Miami Valley Hospital North, Dayton, Ohio

Armes Family Cancer Center, Findlay, Ohio

Blanchard Valley Hospital, Findlay, Ohio

Orion Cancer Care, Findlay, Ohio

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio

Dayton Physicians LLC-Atrium, Franklin, Ohio

Dayton Physicians LLC-Wayne, Greenville, Ohio

Miami Valley Cancer Care and Infusion, Greenville, Ohio

Wayne Hospital, Greenville, Ohio

Greater Dayton Cancer Center, Kettering, Ohio

First Dayton Cancer Care, Kettering, Ohio

Kettering Medical Center, Kettering, Ohio

Springfield Regional Cancer Center, Springfield, Ohio

Springfield Regional Medical Center, Springfield, Ohio

Dayton Physicians LLC - Troy, Troy, Ohio

Upper Valley Medical Center, Troy, Ohio

Saint Joseph Warren Hospital, Warren, Ohio

Saint Elizabeth Youngstown Hospital, Youngstown, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma

Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma

Saint Alphonsus Cancer Care Center-Baker City, Baker City, Oregon

Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Pocono Medical Center, East Stroudsburg, Pennsylvania

Geisinger Medical Center-Cancer Center Hazleton, Hazleton, Pennsylvania

Lehigh Valley Hospital-Hazleton, Hazleton, Pennsylvania

Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania

Lewistown Hospital, Lewistown, Pennsylvania

Geisinger Cancer Services-Pottsville, Pottsville, Pennsylvania

Community Medical Center, Scranton, Pennsylvania

Geisinger Medical Oncology-Selinsgrove, Selinsgrove, Pennsylvania

Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Cancer Institute - Laurens, Clinton, South Carolina

Prisma Health Cancer Institute - Easley, Easley, South Carolina

Gibbs Cancer Center-Gaffney, Gaffney, South Carolina

Prisma Health Cancer Institute - Butternut, Greenville, South Carolina

Prisma Health Cancer Institute - Faris, Greenville, South Carolina

Prisma Health Greenville Memorial Hospital, Greenville, South Carolina

Prisma Health Cancer Institute - Eastside, Greenville, South Carolina

Prisma Health Cancer Institute - Greer, Greer, South Carolina

Gibbs Cancer Center-Pelham, Greer, South Carolina

Prisma Health Cancer Institute - Seneca, Seneca, South Carolina

Spartanburg Medical Center, Spartanburg, South Carolina

SMC Center for Hematology Oncology Union, Union, South Carolina

Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

Memorial Hospital, Chattanooga, Tennessee

Pulmonary Medicine Center of Chattanooga-Hixson, Hixson, Tennessee

Memorial GYN Plus, Ooltewah, Tennessee

Saint Joseph Regional Cancer Center, Bryan, Texas

Parkland Memorial Hospital, Dallas, Texas

UT Southwestern Simmons Cancer Center - RedBird, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Fort Worth, Fort Worth, Texas

UT Southwestern Clinical Center at Richardson/Plano, Richardson, Texas

Highline Medical Center-Main Campus, Burien, Washington

Saint Elizabeth Hospital, Enumclaw, Washington

Saint Francis Hospital, Federal Way, Washington

Saint Clare Hospital, Lakewood, Washington

Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington

Saint Michael Cancer Center, Silverdale, Washington

Franciscan Research Center-Northwest Medical Plaza, Tacoma, Washington

Northwest Medical Specialties PLLC, Tacoma, Washington

United Hospital Center, Bridgeport, West Virginia

WVUH-Berkely Medical Center, Martinsburg, West Virginia

West Virginia University Healthcare, Morgantown, West Virginia

Camden Clark Medical Center, Parkersburg, West Virginia

Langlade Hospital and Cancer Center, Antigo, Wisconsin

Duluth Clinic Ashland, Ashland, Wisconsin

Northwest Wisconsin Cancer Center, Ashland, Wisconsin

Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin

Essentia Health-Hayward Clinic, Hayward, Wisconsin

Gundersen Lutheran Medical Center, La Crosse, Wisconsin

Marshfield Medical Center - Ladysmith, Ladysmith, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Aspirus Medford Hospital, Medford, Wisconsin

Marshfield Medical Center - Minocqua, Minocqua, Wisconsin

Cancer Center of Western Wisconsin, New Richmond, Wisconsin

Aspirus Cancer Care - James Beck Cancer Center, Rhinelander, Wisconsin

Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin

Essentia Health-Spooner Clinic, Spooner, Wisconsin

Aspirus Cancer Care - Stevens Point, Stevens Point, Wisconsin

Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin

Essentia Health Saint Mary's Hospital - Superior, Superior, Wisconsin

Aspirus Regional Cancer Center, Wausau, Wisconsin

Diagnostic and Treatment Center, Weston, Wisconsin

Marshfield Medical Center - Weston, Weston, Wisconsin

Aspirus Cancer Care - Wisconsin Rapids, Wisconsin Rapids, Wisconsin

Billings Clinic-Cody, Cody, Wyoming

Welch Cancer Center, Sheridan, Wyoming

Conditions: Infiltrating Bladder Urothelial Carcinoma, Stage II Bladder Urothelial Carcinoma, Stage III Bladder Urothelial Carcinoma

Learn More ›

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)

NCT03221426

Completed

The purpose of this study is to evaluate the efficacy of pembrolizumab (MK-3745) in the neoadjuvant (prior to surgery) or adjuvant (after surgery) treatment of previously untreated adults with gastric and gastroesophageal junction (GEJ) adenocarcinoma. The primary study hypotheses are that: * Neoadjuvant and adjuvant pembrolizumab plus chemotherapy, followed by adjuvant pembrolizumab is superior to neoadjuvant and adjuvant placebo plus chemotherapy, followed by adjuvant placebo in terms of Eve... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/24/2025

Locations: City of Hope ( Site 0005), Duarte, California +170 locations

City of Hope ( Site 0005), Duarte, California

Yale Cancer Center ( Site 0016), New Haven, Connecticut

Georgetown University ( Site 0015), Washington, District of Columbia

Northwestern University - Robert H. Lurie Comprehensive Cancer Center ( Site 0018), Chicago, Illinois

The University of Chicago Medical Center ( Site 0004), Chicago, Illinois

Roswell Park Cancer Institute ( Site 0001), Buffalo, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 0019), New York, New York

Memorial Sloan Kettering ( Site 0024), New York, New York

Weill Cornell Medical Center ( Site 0023), New York, New York

University of Rochester ( Site 0011), Rochester, New York

Fox Chase Cancer Center ( Site 0006), Philadelphia, Pennsylvania

Temple University Hospital ( Site 0026), Philadelphia, Pennsylvania

University of Utah, Huntsman Cancer Institute ( Site 0012), Salt Lake City, Utah

Virginia Cancer Specialists, PC ( Site 0010), Fairfax, Virginia

Institut Jules Bordet ( Site 0480), Brussels, Bruxelles-Capitale, Region De

Hopital Erasme ULB ( Site 0484), Brussels, Bruxelles-Capitale, Region De

UCL Saint Luc ( Site 0479), Bruxelles, Bruxelles-Capitale, Region De

Grand Hopital de Charleroi ( Site 0478), Charleroi, Hainaut

CHU de Liege ( Site 0482), Liège, Liege

CHU UCL Namur Site de Godinne ( Site 0485), Yvoir, Namur

UZ Gent ( Site 0486), Gent, Oost-Vlaanderen

UZ Leuven ( Site 0483), Leuven, Vlaams-Brabant

AZ Groeninge ( Site 0481), Kortrijk, West-Vlaanderen

Instituto do Cancer do Ceara ( Site 0311), Fortaleza, Ceara

Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da Pucrs ( Site 0308), Porto Alegre, Rio Grande Do Sul

CEPON - Centro de Pesquisas Oncologicas ( Site 0302), Florianopolis, Santa Catarina

Fundacao Pio XII - Hospital de Cancer de Barretos ( Site 0301), Barretos, Sao Paulo

Hospital de Base de Sao Jose de Rio Preto ( Site 0304), Sao Jose Rio Preto, Sao Paulo

Instituto Nacional Do Cancer Jose Alencar Gomes Da Silva ( Site 0307), Rio de Janeiro, Not set

Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0305), Sao Paulo, Not set

Hospital Israelita Albert Einstein ( Site 0309), Sao Paulo, Not set

Cross Cancer Institute ( Site 0033), Edmonton, Alberta

Moncton Hospital - Horizon Health Network ( Site 0038), Moncton, New Brunswick

Sunnybrook Research Institute ( Site 0032), Toronto, Ontario

CISSS de la Monteregie-Centre ( Site 0039), Greenfield Park, Quebec

CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont ( Site 0040), Montreal, Quebec

Jewish General Hospital ( Site 0034), Montreal, Quebec

CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0035), Sherbrooke, Quebec

CHU de Quebec - Hotel-Dieu de Quebec ( Site 0042), Quebec, Not set

Instituto Clinico del Sur. ICOS ( Site 0290), Temuco, Araucania

Hospital Regional Rancagua Libertador Bernardo O Higgins ( Site 0299), Rancagua, Lbtdr Gen Bernardo O Higgins

Fundacion Arturo Lopez Perez FALP ( Site 0286), Santiago, Region M. De Santiago

Pontificia Universidad Catolica de Chile ( Site 0285), Santiago, Region M. De Santiago

Hospital Clinico Universidad de Chile ( Site 0287), Santiago, Region M. De Santiago

Beijing Cancer Hospital ( Site 0221), Beijing, Beijing

Zhejiang Cancer Hospital ( Site 0231), Hangzhou, Zhejiang

Sir Run Run Shaw Hospital ( Site 0233), Hangzhou, Zhejiang

SA Pohja-Eesti Regionaalhaigla ( Site 0526), Tallinn, Harjumaa

Hopital Prive Jean Mermoz ( Site 0462), Lyon, Auvergne

Institut Paoli Calmettes ( Site 0472), Marseille, Bouches-du-Rhone

CHU Reims - Hopital Robert Debre ( Site 0465), Reims, Champagne-Ardenne

CHU Brest - Institut de Cancerologie et d Hematologie ( Site 0474), Brest, Finistere

CHU Toulouse - Hopital Rangueil ( Site 0470), Toulouse, Haute-Garonne

Institut du Cancer de Montpellier ( Site 0473), Montpellier, Herault

Centre Eugene Marquis ( Site 0466), Rennes, Ille-et-Vilaine

Institut de Cancerologie de l Ouest Centre Rene Gauducheau ( Site 0469), Saint Herblain, Loire-Atlantique

CHRU Lille - Hopital Claude Huriez ( Site 0461), Lille, Nord

CHU Poitiers - Pole Regional de Cancerologie ( Site 0467), Poitiers, Vienne

CHU Hopital Saint Antoine ( Site 0471), Paris, Not set

Institut Mutualiste Montsouris ( Site 0463), Paris, Not set

Klinikum Esslingen GmbH ( Site 0453), Esslingen, Baden-Wurttemberg

Universitaetsklinikum Freiburg ( Site 0450), Freiburg, Baden-Wurttemberg

Klinikum der Universitaet in Muenchen ( Site 0446), Muenchen, Bayern

Medizinische Hochschule Hannover ( Site 0449), Hannover, Niedersachsen

Kliniken Essen Mitte Gmbh Evang. Huyssens Stiftung ( Site 0445), Essen, Nordrhein-Westfalen

Medizinische klinilk und Poliklinik Johannes Gutenberg Univ ( Site 0455), Mainz, Rheinland-Pfalz

Universitaetsklinikum Carl Gustav Carus der TU Dresden ( Site 0448), Dresden, Sachsen

Haematologisch-Onkologische Praxis Eppendorf Facharztzentrum Eppendorf - Hope ( Site 0454), Hamburg, Not set

Integra Cancer Institute ( Site 0262), Guatemala, Not set

Grupo Medico Angeles ( Site 0261), Guatemala, Not set

Centro Medico Integral De Cancerología (CEMIC) ( Site 0260), Quetzaltenango, Not set

Soroka University M.C ( Site 0385), Beer Sheva, HaDarom

Meir medical center ( Site 0386), Kfar Saba, HaMerkaz

Sourasky Medical Center. ( Site 0382), Tel-Aviv, Tell Abib

Rambam Health Care Campus ( Site 0381), Haifa, Not set

Hadassah Medical Center. Ein Kerem ( Site 0383), Jerusalem, Not set

Rabin-Medical Center ( Site 0384), Petah Tikva, Not set

Sheba Medical center ( Site 0387), Ramat Gan, Not set

IRCCS Istituto Oncologico Veneto ( Site 0431), Padova, Abruzzo

Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0430), Milano, Lombardia

Istituto Clinico Humanitas Research Hospital ( Site 0432), Rozzano, Milano

IRCCS Policlinico San Donato ( Site 0433), San Donato Milanese, Milano

Azienda Ospedaliero Universitaria di Modena Policlinico ( Site 0429), Modena, Not set

Seconda Universita Napoli ( Site 0436), Napoli, Not set

A.O.U. Santa Maria della Misericordia di Udine ( Site 0434), Udine, Not set

Aichi Cancer Center Hospital ( Site 0165), Nagoya, Aichi

National Cancer Center Hospital East ( Site 0178), Kashiwa, Chiba

National Hospital Organization Shikoku Cancer Center ( Site 0186), Matsuyama, Ehime

Hokkaido University Hospital ( Site 0160), Sapporo, Hokkaido

Hyogo Cancer Center ( Site 0182), Akashi, Hyogo

Kobe University Hospital ( Site 0188), Kobe, Hyogo

Kobe City Medical Center General Hospital ( Site 0181), Kobe, Hyogo

Ibaraki Prefectural Central Hospital ( Site 0177), Kasama, Ibaraki

Iwate Medical University Hospital ( Site 0184), Shiwa-gun, Iwate

St. Marianna University School of Medicine Hospital ( Site 0187), Kawasaki, Kanagawa

Kanagawa Cancer Center ( Site 0167), Yokohama, Kanagawa

Kansai Medical University Hospital ( Site 0190), Hirakata, Osaka

Osaka University Hospital ( Site 0162), Suita, Osaka

Osaka Medical College Hospital ( Site 0168), Takatsuki, Osaka

Saitama Cancer Center ( Site 0170), Kitaadachi-gun, Saitama

Shizuoka Cancer Center Hospital and Research Institute ( Site 0176), Sunto-gun, Shizuoka

Chiba Cancer Center ( Site 0180), Chiba, Not set

National Hospital Organization Kyushu Cancer Center ( Site 0172), Fukuoka, Not set

Kyushu University Hospital ( Site 0173), Fukuoka, Not set

Gifu University Hospital ( Site 0166), Gifu, Not set

Hiroshima City Hiroshima Citizens Hospital ( Site 0171), Hiroshima, Not set

Kochi Health Sciences Center ( Site 0189), Kochi, Not set

Kumamoto University Hospital ( Site 0164), Kumamoto, Not set

Niigata Cancer Center Hospital ( Site 0169), Niigata, Not set

Osaka International Cancer Institute ( Site 0161), Osaka, Not set

Osaka General Medical Center ( Site 0159), Osaka, Not set

National Cancer Center Hospital ( Site 0179), Tokyo, Not set

Tokyo Metropolitan Komagome Hospital ( Site 0183), Tokyo, Not set

The Cancer Institute Hospital of JFCR ( Site 0185), Tokyo, Not set

Toyama Prefectural Central Hospital ( Site 0163), Toyama, Not set

Chonnam National University Hwasun Hospital ( Site 0083), Hwasun Gun, Jeonranamdo

Seoul National University Bundang Hospital ( Site 0085), Seongnam-si, Kyonggi-do

Kyungpook National University Chilgok Hospital ( Site 0089), Daegu, Taegu-Kwangyokshi

Gachon University Gil Medical Center ( Site 0087), Incheon, Not set

Korea University Anam Hospital ( Site 0084), Seoul, Not set

Seoul National University Hospital -SNUH- ( Site 0080), Seoul, Not set

Severance Hospital Yonsei University Health System ( Site 0081), Seoul, Not set

Asan Medical Center ( Site 0082), Seoul, Not set

Gangnam Severance Hospital ( Site 0088), Seoul, Not set

SMG-SNU BORAMAE Medical Center ( Site 0086), Seoul, Not set

Riga East Clinical University Hospital ( Site 0550), Riga, Not set

LSMUL Kauno Klinikos ( Site 0570), Kaunas, Not set

Nacionalinis Vezio Institutas ( Site 0569), Vilnius, Not set

Vilniaus Universiteto Ligonine Santaros Klinikos ( Site 0568), Vilnius, Not set

Hospital Kuala Lumpur ( Site 0146), Kuala Lumpur, Not set

University Malaya Medical Centre ( Site 0143), Kuala Lumpur, Not set

St. Luke s Medical Center ( Site 0622), Quezon City, National Capital Region

Wojewodzki Szpital Specjalistyczny we Wroclawiu ( Site 0358), Wroclaw, Dolnoslaskie

Samodzielny Publiczny Szpital Kliniczny Nr 1 w Lublinie ( Site 0351), Lublin, Lubelskie

Szpital Uniwersytecki w Krakowie ( Site 0352), Krakow, Malopolskie

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 0349), Warszawa, Mazowieckie

Mazowiecki Szpital Onkologiczny ( Site 0363), Wieliszew, Mazowieckie

Szpital Specjalistyczny w Koscierzynie Sp. z o.o. ( Site 0353), Koscierzyna, Pomorskie

Beskidzkie Centrum Onkologii im. Jana Pawla II ( Site 0354), Bielsko-Biala, Slaskie

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 0361), Gliwice, Slaskie

SPZOZ WSS nr 3 w Rybniku ( Site 0357), Rybnik, Slaskie

Kaluga Regional Clinical Oncology Center ( Site 0345), Kaluga, Kaluzskaja Oblast

SBHI Leningrad Regional Clinical Hospital ( Site 0496), Saint Petersburg, Leningradskaya Oblast

National Medical and Surgical Center n.a. N.I.Pirogov ( Site 0338), Moscow, Moskva

Blokhin National Medical Oncology ( Site 0494), Moscow, Moskva

Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 0344), Saint Petersburg, Sankt-Peterburg

Leningrad Regional Oncology Center ( Site 0335), Saint-Petersburg, Sankt-Peterburg

City clinical oncological dispensary ( Site 0336), Sankt-Petersburg, Sankt-Peterburg

Tomsk Scientific Research Institute of Oncology ( Site 0337), Tomsk, Tomskaya Oblast

National University Hospital ( Site 0095), Singapore, Central Singapore

National Cancer Centre Singapore ( Site 0097), Singapore, Central Singapore

Oncocare Cancer Centre ( Site 0096), Singapore, Central Singapore

Taipei Medical University Shuang Ho Hospital ( Site 0068), New Taipei, Not set

National Cheng Kung University Hospital ( Site 0067), Tainan, Not set

National Taiwan University Hospital ( Site 0063), Taipei, Not set

Mackay Memorial Hospital ( Site 0065), Taipei, Not set

Koo Foundation Sun Yat-Sen Cancer Center ( Site 0066), Taipei, Not set

Chang Gung Medical Foundation. Linkou ( Site 0064), Taoyuan, Not set

City Clinical Hosp.4 of DCC ( Site 0325), Dnipro, Dnipropetrovska Oblast

MI Kryvyi Rih Oncology Dispensary of Dnipropetrovsk Regional Council ( Site 0589), Kryviy Rih, Dnipropetrovska Oblast

Ivano-Frankivsk Regional Oncology Clinical Dispensary ( Site 0321), Ivano-Frankivsk, Ivano-Frankivska Oblast

Communal non profit enterprise Regional Clinical Oncology Center ( Site 0591), Kharkiv, Kharkivska Oblast

National Cancer Institute of the MoH of Ukraine ( Site 0319), Kyiv, Kyivska Oblast

Kyiv City Clinical Oncology Center ( Site 0590), Kyiv, Kyivska Oblast

University Hospitals Bristol NHS Foundation Trust ( Site 0407), Bristol, Bristol, City Of

Ninewells Hospital and Medical School ( Site 0406), Dundee, Dundee City

Royal Free London NHS Foundation Trust ( Site 0403), London, London, City Of

The Royal Marsden Foundation Trust ( Site 0405), London, London, City Of

Imperial College Healthcare NHS Trust ( Site 0402), London, London, City Of

Royal Marsden NHS Foundation Trust ( Site 0400), Sutton, Surrey

The Christie NHS Foundation Trust ( Site 0397), Manchester, Not set

Conditions: Gastric Cancer, Gastroesophageal Junction Cancer

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Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer

NCT03682068

Active Not Recruiting

This is a randomized, open-label, controlled, multi-center, global Phase III study to determine the efficacy and safety of combining durvalumab ± tremelimumab with standard of care (SoC) chemotherapy (cisplatin + gemcitabine or carboplatin + gemcitabine doublet) followed by durvalumab monotherapy versus SoC alone as first-line chemotherapy in patients with histologically or cytologically documented, unresectable, locally advanced or metastatic transitional cell carcinoma of the urothelium (inclu... Read More

Gender:

ALL

Ages:

Between 18 years and 130 years

Trial Updated:

06/24/2025

Locations: Research Site, Birmingham, Alabama +221 locations

Research Site, Birmingham, Alabama

Research Site, Bakersfield, California

Research Site, Fullerton, California

Research Site, Los Angeles, California

Research Site, Salinas, California

Research Site, Santa Barbara, California

Research Site, Truckee, California

Research Site, New Haven, Connecticut

Research Site, Washington, District of Columbia

Research Site, Orlando, Florida

Research Site, Chicago, Illinois

Research Site, Fort Wayne, Indiana

Research Site, Kansas City, Kansas

Research Site, Louisville, Kentucky

Research Site, New Orleans, Louisiana

Research Site, Grand Rapids, Michigan

Research Site, Bozeman, Montana

Research Site, New Hyde Park, New York

Research Site, New York, New York

Research Site, Rochester, New York

Research Site, Germantown, Tennessee

Research Site, Fort Worth, Texas

Research Site, Buenos Aires, Not set

Research Site, Ciudad de Buenos Aires, Not set

Research Site, Rosario, Not set

Research Site, Box Hill, Not set

Research Site, Elizabeth Vale, Not set

Research Site, Kogarah, Not set

Research Site, Macquarie University, Not set

Research Site, Murdoch, Not set

Research Site, Orange, Not set

Research Site, South Brisbane, Not set

Research Site, St Albans, Not set

Research Site, Curitiba, Not set

Research Site, Fortaleza, Not set

Research Site, Porto Alegre, Not set

Research Site, Ribeirão Preto, Not set

Research Site, Rio de Janeiro, Not set

Research Site, Salvador, Not set

Research Site, Santa Maria, Not set

Research Site, Sao Paulo, Not set

Research Site, São José do Rio Preto, Not set

Research Site, São Paulo, Not set

Research Site, Pleven, Not set

Research Site, Plovdiv, Not set

Research Site, Sofia, Not set

Research Site, Varna, Not set

Research Site, Calgary, Alberta

Research Site, Edmonton, Alberta

Research Site, Vancouver, British Columbia

Research Site, Hamilton, Ontario

Research Site, Ottawa, Ontario

Research Site, Toronto, Ontario

Research Site, Montreal, Quebec

Research Site, Beijing, Not set

Research Site, Changchun, Not set

Research Site, Changsha, Not set

Research Site, Chongqing, Not set

Research Site, Dalian, Not set

Research Site, Guangzhou, Not set

Research Site, Hangzhou, Not set

Research Site, Jinan, Not set

Research Site, Nanchang, Not set

Research Site, Nanjing, Not set

Research Site, Shanghai, Not set

Research Site, Shenyang, Not set

Research Site, Suzhou, Not set

Research Site, Tianjin, Not set

Research Site, Urumqi, Not set

Research Site, Wuhan, Not set

Research Site, Xi'an, Not set

Research Site, Brno, Not set

Research Site, Hradec Kralove, Not set

Research Site, Olomouc, Not set

Research Site, Ostrava, Not set

Research Site, Praha 2, Not set

Research Site, Praha 8, Not set

Research Site, Praha, Not set

Research Site, Budapest, Not set

Research Site, Debrecen, Not set

Research Site, Győr, Not set

Research Site, Kecskemét, Not set

Research Site, Szolnok, Not set

Research Site, Gurgaon, Not set

Research Site, Hubli, Not set

Research Site, Kolkata, Not set

Research Site, Mysuru, Not set

Research Site, Nagpur, Not set

Research Site, Nasik, Not set

Research Site, New Delhi, Not set

Research Site, Pune, Not set

Research Site, Haifa, Not set

Research Site, Jerusalem, Not set

Research Site, Kfar Saba, Not set

Research Site, Petach-Tikva, Not set

Research Site, Ramat Gan, Not set

Research Site, Arezzo, Not set

Research Site, Milano, Not set

Research Site, Napoli, Not set

Research Site, Orbassano, Not set

Research Site, Parma, Not set

Research Site, Pavia, Not set

Research Site, Roma, Not set

Research Site, Terni, Not set

Research Site, Verona, Not set

Research Site, Bunkyo-ku, Not set

Research Site, Chuo-ku, Not set

Research Site, Fukuoka-shi, Not set

Research Site, Hirosaki-shi, Not set

Research Site, Kanazawa-shi, Not set

Research Site, Kita-gun, Not set

Research Site, Koshigaya-shi, Not set

Research Site, Koto-ku, Not set

Research Site, Kumamoto-shi, Not set

Research Site, Kyoto-shi, Not set

Research Site, Miyazaki-city, Not set

Research Site, Nagasaki-shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Niigata-shi, Not set

Research Site, Osaka-shi, Not set

Research Site, Osakasayama-shi, Not set

Research Site, Shinjuku-ku, Not set

Research Site, Suita-shi, Not set

Research Site, Toyama-shi, Not set

Research Site, Yokohama-shi, Not set

Research Site, Goyang-si, Not set

Research Site, Incheon, Not set

Research Site, Seoul, Not set

Research Site, Suwon, Not set

Research Site, Bacolod, Not set

Research Site, Baguio City, Not set

Research Site, Cebu, Not set

Research Site, Davao City, Not set

Research Site, Makati, Not set

Research Site, Manila, Not set

Research Site, Quezon City, Not set

Research Site, Bialystok, Not set

Research Site, Gdańsk, Not set

Research Site, Grudziądz, Not set

Research Site, Koszalin, Not set

Research Site, Kraków, Not set

Research Site, Olsztyn, Not set

Research Site, Poznan, Not set

Research Site, Radom, Not set

Research Site, Warszawa, Not set

Research Site, Ivanovo, Not set

Research Site, Krasnoyarsk, Not set

Research Site, Moscow, Not set

Research Site, Nizhniy Novgorod, Not set

Research Site, Omsk, Not set

Research Site, Rostov-on-Don, Not set

Research Site, Saint-Petersburg, Not set

Research Site, St. Petersburg, Not set

Research Site, Tyumen, Not set

Research Site, Vologda, Not set

Research Site, Barcelona, Not set

Research Site, Lugo, Not set

Research Site, Madrid, Not set

Research Site, Malaga, Not set

Research Site, Santander, Not set

Research Site, Sevilla, Not set

Research Site, Taichung, Not set

Research Site, Tainan, Not set

Research Site, Taipei City, Not set

Research Site, Taipei, Not set

Research Site, Taoyuan, Not set

Research Site, Bangkok, Not set

Research Site, Khon Kaen, Not set

Research Site, Mueang, Not set

Research Site, Songkla, Not set

Research Site, Adana, Not set

Research Site, Adapazari, Not set

Research Site, Ankara, Not set

Research Site, Edirne, Not set

Research Site, Istanbul, Not set

Research Site, Izmir, Not set

Research Site, Ha Noi, Not set

Research Site, Hanoi, Not set

Research Site, Ho Chi Minh, Not set

Conditions: Unresectable Locally Advanced Urothelial Cancer, Metastatic Urothelial Cancer

Learn More ›

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