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                    Cyclophosphamide Treatment Options in California
A collection of 693 research studies where Cyclophosphamide is the interventional treatment. These studies are located in the California, United States. Cyclophosphamide is used for conditions such as Breast Cancer, Lymphoma and Leukemia.
            25 - 36 of 693
        Featured Trial
                
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                            Conditions: 
                                    
        
            
                        Healthy
                    
                                    
                        Healthy Volunteers
                    
                                    
                        Healthy Subjects
                    
                                    
                        Healthy Volunteer
                    
                                    
                        Healthy Participants
                    
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                            Conditions: 
                                    
        
            
                        Overweight
                    
                                    
                        Overweight and Obesity
                    
                                    
                        Obesity
                    
                                    
                        Weight Loss
                    
                                    
                        Morbid Obesity
                    
                                    Featured Trial
                
                Stroke Clinical Study
            
        Recruiting
            
        A clinical study for people that suffer with Stroke
    
    
                            Conditions: 
                                    
        
            
                        Stroke
                    
                                    Featured Trial
                
                Chronic Kidney Disease (CKD) Clinical Study
            
        Recruiting
            
        A clinical study for people that suffer with Chronic Kidney Disease (CKD)
    
    
                            Conditions: 
                                    
        
            
                        Chronic Kidney Disease (CKD)
                    
                                    
                
                                    A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis
                                
            
            
        Active Not Recruiting
                            
            
                The purpose of this study is to characterize cardiac safety of Daratumumab, Cyclophosphamide, Bortezomib, and Dexamethasone (D-VCd) treatment regimens (Arm A: daratumumab + immediate VCd treatment and Arm B: daratumumab + deferred VCd) in newly diagnosed systemic amyloid light chain (AL) amyloidosis with cardiac involvement and to identify potential mitigation strategies for cardiac toxicity (cohort 1); to characterize the pharmacokinetics of subcutaneous (SC) daratumumab, among racial and ethni...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                08/14/2025
            
            Locations: City of Hope, Duarte, California         
        
        
            Conditions: Amyloidosis
        
            
        
    
                
                                    A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
                                
            
            
        Recruiting
                            
            
                The purpose of this study is to evaluate if zilovertamab vedotin with standard treatment can help people live longer without the cancer growing or spreading than people who receive standard treatment alone.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                08/14/2025
            
            Locations: Cancer Blood and Specialty Clinic ( Site 0109), Los Alamitos, California  +1 locations         
        
        
            Conditions: Diffuse Large B-Cell Lymphoma
        
            
        
    
                
                                    A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)
                                
            
            
        Recruiting
                            
            
                This phase III trial studies using risk factors in determining treatment for children with favorable tissue (histology) Wilms tumors (FHWT). Wilms Tumor is the most common type of kidney cancer in children, and FHWT is the most common subtype. Previous large clinical trials have established treatment plans that are likely to cure most children with FHWT, however some children still have their cancer come back (called relapse) and not all survive. Previous research has identified features of FHWT...  Read More             
        
        
    Gender:
                ALL
            Ages:
                30 years and below
            Trial Updated:
                08/14/2025
            
            Locations: Loma Linda University Medical Center, Loma Linda, California  +6 locations         
        
        
            Conditions: Stage I Mixed Cell Type Kidney Wilms Tumor, Stage II Mixed Cell Type Kidney Wilms Tumor, Stage III Mixed Cell Type Kidney Wilms Tumor, Stage IV Mixed Cell Type Kidney Wilms Tumor
        
            
        
    
                
                                    A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
                                
            
            
        Recruiting
                            
            
                Researchers are looking for ways to treat germinal center B-cell-like diffuse large B-cell lymphoma (GCB DLBCL). DLBCL is a fast-growing blood cancer that affects B-cells. GCB is a type of DLBCL that affects young B-cells that are still maturing.
The goal of this study is to learn if more people who receive zilovertamab vedotin (MK-2140) and R-CHP have the cancer respond (go away) than those who receive polatuzumab vedotin and R-CHP.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                08/14/2025
            
            Locations: Bass Medical Group ( Site 0123), Walnut Creek, California         
        
        
            Conditions: Lymphoma, Large B-Cell, Diffuse
        
            
        
    
                
                                    Recombinant Erwinia Asparaginase and Venetoclax in Combination With Blinatumomab for the Treatment of Relapsed or Refractory CD19 Positive B-cell Acute Lymphoblastic Leukemia
                                
            
            
        Not Yet Recruiting
                            
            
                This phase I/Ib trial tests the safety and side effects of asparaginase Erwinia chrysanthemi-recombinant-rywn (recombinant Erwinia asparaginase) and venetoclax in combination with blinatumomab and how well the combination works in treating patients with CD19 positive B-cell acute lymphoblastic leukemia (ALL) that has come back after a period of improvement (relapsed) or that has not responded to previous treatment (refractory). Asparaginase Erwinia chrysanthemi, a type of protein synthesis inhib...  Read More             
        
        
    Gender:
                ALL
            Ages:
                Between 12 years and 55 years
            Trial Updated:
                08/14/2025
            
            Locations: City of Hope Medical Center, Duarte, California         
        
        
            Conditions: Recurrent B Acute Lymphoblastic Leukemia, Refractory B Acute Lymphoblastic Leukemia
        
            
        
    
                
                                    A Study of CC-97540 (BMS-986353), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)
                                
            
            
        Recruiting
                            
            
                The purpose of this study is to evaluate the efficacy, safety and drug levels of CC-97540 in participants with active systemic lupus erythematosus (SLE) including lupus nephritis with inadequate response to glucocorticoids and at least 2 immunosuppressants.             
        
        
    Gender:
                ALL
            Ages:
                16 years and above
            Trial Updated:
                08/14/2025
            
            Locations: Local Institution - 0038, Los Angeles, California  +2 locations         
        
        
            Conditions: Lupus Erythematosus, Systemic, Lupus Nephritis
        
            
        
    
                
                                    GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults
                                
            
            
        Not Yet Recruiting
                            
            
                This is a single-site, open-label Phase 1 clinical trial evaluating the feasibility, safety, and preliminary activity of autologous GPC2-targeted chimeric antigen receptor (CAR) T cells administered via intracerebroventricular (ICV) infusion in children and young adults with relapsed or refractory medulloblastoma or other eligible Central Nervous System (CNS) embryonal tumors.             
        
        
    Gender:
                ALL
            Ages:
                Between 1 year and 30 years
            Trial Updated:
                08/13/2025
            
            Locations: Lucile Packard Children's Hospital Stanford, Palo Alto, California         
        
        
            Conditions: Medulloblastoma, Central Nervous System Embryonal Tumor, Refractory Medulloblastoma, Recurrent Medulloblastoma, Pediatric Brain Tumor, Embryonal Tumor With Multilayered Rosettes (ETMR), Pineoblastoma, Atypical Teratoid/Rhabdoid Tumor (ATRT) of the CNS, CNS Neuroblastoma, FOXR2-activated
        
            
        
    
                
                                    A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
                                
            
            
        Recruiting
                            
            
                This pilot trial assesses the effect of the combination of blinatumomab with dasatinib or imatinib and standard chemotherapy for treating patients with Philadelphia chromosome positive (Ph+) or ABL-class Philadelphia chromosome-like (Ph-like) B-Cell acute lymphoblastic leukemia (B-ALL). Blinatumomab is a bispecific antibody that binds to two different proteins-one on the surface of cancer cells and one on the surface of cells in the immune system. An antibody is a protein made by the immune syst...  Read More             
        
        
    Gender:
                ALL
            Ages:
                Between 366 days and 46 years
            Trial Updated:
                08/13/2025
            
            Locations: Loma Linda University Medical Center, Loma Linda, California  +1 locations         
        
        
            Conditions: B Acute Lymphoblastic Leukemia
        
            
        
    
                
                                    Phase 2 Study of AFM13 in Combination With AB-101 in Subjects With R/R HL and CD30+ PTCL
                                
            
            
        Terminated
                            
            
                AFM13-203 is a phase 2, open-label, multi-center, multi-cohort study with a safety run-in followed by expansion cohorts. The study is evaluating the safety and efficacy of AFM13 in combination with AB-101 in subjects with R/R classical HL and CD30-positive PTCL.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                08/12/2025
            
            Locations: City of Hope National Medical Center, Duarte, California  +1 locations         
        
        
            Conditions: Relapsed or Refractory Hodgkin Lymphoma, Peripheral T Cell Lymphoma
        
            
        
    
                
                                    Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
                                
            
            
        Active Not Recruiting
                            
            
                This phase III trial studies ibrutinib and rituximab to see how well they work compared to fludarabine phosphate, cyclophosphamide, and rituximab in treating patients with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as fludarabine phosphate and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cel...  Read More             
        
        
    Gender:
                ALL
            Ages:
                Between 18 years and 70 years
            Trial Updated:
                08/12/2025
            
            Locations: Kaiser Permanente-Anaheim, Anaheim, California  +65 locations         
        
        
            Conditions: Anemia, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
        
            
        
    
                
                                    A Phase 1/2 Trial of ADI-270 in ccRCC
                                
            
            
        Active Not Recruiting
                            
            
                This is a Phase 1/2 multicenter, open-label, dose escalation, and dose expansion study of ADI-270 - an Engineered gamma-delta Chimeric Receptor \[CAR\] Vδ1 T Cell product Targeting CD70 - in patients with R/R ccRCC.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                08/12/2025
            
            Locations: Adicet Clinical Trials, Redwood City, California         
        
        
            Conditions: Clear Cell Renal Cell Carcinoma
        
            
        
    
                
                                    Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma
                                
            
            
        Active Not Recruiting
                            
            
                This randomized phase III trial studies how well combination chemotherapy with or without ganitumab works in treating patients with newly diagnosed Ewing sarcoma that has spread to other parts of the body. Treatment with drugs that block the IGF-1R pathway, such as ganitumab, may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide, work in different ways to stop the growth of tumor...  Read More             
        
        
    Gender:
                ALL
            Ages:
                50 years and below
            Trial Updated:
                08/12/2025
            
            Locations: Kaiser Permanente Downey Medical Center, Downey, California  +15 locations         
        
        
            Conditions: Metastatic Ewing Sarcoma, Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Neoplasm in the Bone Marrow, Metastatic Malignant Neoplasm in the Lung, Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone, Peripheral Primitive Neuroectodermal Tumor of Soft Tissues
        
            
        
    25 - 36 of 693
            