Cyclophosphamide Treatment Options

A collection of 2185 research studies where Cyclophosphamide is the interventional treatment. These studies are located in the United States . Cyclophosphamide is used for conditions such as Breast Cancer, Lymphoma and Leukemia.

Home

All Treatments

Cyclophosphamide

Show Filters

Match to Clinical Trials

Access to cutting-edge treatments

Latest clinical trials

Find trials in your area

Start Matching

Filter by Age

Featured Trial

Healthy Participants Needed (Colonoscopy + Cancer Screening)

Recruiting

Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.

Conditions:

Healthy

Healthy Volunteers

Healthy Subjects

Healthy Volunteer

Healthy Participants

Learn More

Featured Trial

Buy Retatrutide Online Through Celia

Recruiting

Retatrutide (formerly M25) is an investigational peptide being studied for its potential in supporting weight management and metabolic health. It acts on GLP-1, GIP, and glucagon receptors to influence appetite, energy regulation, and fat metabolism.

Conditions:

Healthy

Learn More

Featured Offer

Lose 20% of Body Weight With GLP-1's

Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to tirzepatide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.

Semaglutide and Tirzepatide are advanced GLP-1 medications designed to support weight management and metabolic health. They work by targeting GLP-1 receptors in the body, helping regulate appetite, improve blood sugar control, and support sustainable weight loss (up to 22% of body weight).

Get $50 off your first order using promo code: policy-lab-50

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

Learn More

Featured Trial

Birth Control Clinical Research Study

Recruiting

Living with obesity and looking for a birth control option that is right for you? Clinical trials are now enrolling women with a body mass index (BMI) of 30 or more in the area to help study a potential new progestin-only contraceptive patch. Participating in research studies can help advance birth control options. Don’t let financial stress hold you back. All study-related assessments, care, and study patch are available at no cost. You may also be reimbursed for study-related travel.

Conditions:

Obesity

Overweight

Overweight and Obesity

Learn More

Carfilzomib, Rituximab, and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Lymphoma

NCT02073097

Completed

This phase I/II trial studies the side effects and best dose of carfilzomib when given together with rituximab and combination chemotherapy and to see how well they work in treating patients with diffuse large B-cell lymphoma. Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as rituximab, can block cancer growth by finding cancer cells and helping kill them. Drugs used in chemotherapy work in different ways to sto... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/02/2024

Locations: Roswell Park Comprehensive Cancer Center, Buffalo, New York +2 locations

Conditions: Contiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma

Learn More ›

A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation

NCT06399393

Recruiting

The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT).

Gender:

All

Ages:

18 years and above

Trial Updated:

05/01/2024

Locations: Banner MD Anderson Cancer Center, Gilbert, Arizona +117 locations

Banner MD Anderson Cancer Center, Gilbert, Arizona

Mayo Clinic in Arizona - Scottsdale, Scottsdale, Arizona

UCLA Hematology/Oncology - Westwood (Building 200 Suite 120), Los Angeles, California

University of California, Irvine (UCI) Health - UC Irvine Medical Center, Orange, California

University of California Davis (UC Davis) Comprehensive Cancer Center, Sacramento, California

Colorado Blood Cancer Institute, Denver, Colorado

Yale University School of Medicine, New Haven, Connecticut

Mayo Clinic in Florida, Jacksonville, Florida

AdventHealth Orlando, Orlando, Florida

Moffitt Cancer Center, Tampa, Florida

Winship Cancer Institute, Emory University, Atlanta, Georgia

Northside Hospital, Atlanta, Georgia

Massachusetts General Hospital, Boston, Massachusetts

Boston Medical Center, Boston, Massachusetts

Local Institution - 0123, Ann Arbor, Michigan

Ascension Providence Hospital, Southfield, Michigan

Local Institution - 0119, Minneapolis, Minnesota

Mayo Clinic in Rochester, Minnesota, Rochester, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Columbia University Irving Medical Center, New York, New York

Novant Health Cancer Institute - Elizabeth, Charlotte, North Carolina

Wake Forest Baptist Health, Winston-Salem, North Carolina

University Hospitals Cleveland Medical Center, Cleveland, Ohio

The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus, Ohio

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

St. David's South Austin Medical Center, Austin, Texas

UT Southwestern Medical Center, Dallas, Texas

Houston Methodist Hospital, Houston, Texas

University of Texas MD Anderson Cancer Center, Houston, Texas

Local Institution - 0136, Richmond, Virginia

Royal Prince Alfred Hospital, Camperdown, New South Wales

Local Institution - 0005, Brisbane, Queensland

Peter MacCallum Cancer Centre, Melbourne, Victoria

The Alfred Hospital, Melbourne, Victoria

St Vincent's Hospital, Melbourne, Victoria

Fiona Stanley Hospital, Murdoch, Western Australia

Uniklinikum Salzburg, Salzburg, Not set

Medizinische Universität Wien, Wien, Not set

Institut Jules Bordet, Anderlecht, Bruxelles-Capitale, Région De

UZ Brussel, Brussels, Bruxelles-Capitale, Région De

Local Institution - 0133, Edmonton, Alberta

Hamilton Health Sciences-Juravinski Cancer Centre, Hamilton, Ontario

Local Institution - 0134, Montreal, Quebec

Local Institution - 0036, Brno, Brno-město

Local Institution - 0034, Hradec Kralove, Hradec Králové

Local Institution - 0035, Olomouc, Olomoucký Kraj

Local Institution - 0033, Praha 2, Not set

Local Institution - 0070, Odense, Syddanmark

CHU Bordeaux Haut-Leveque, Pessac, Aquitaine

Institut Paoli-Calmettes, Marseille, Bouches-du-Rhône

Hopital Claude Huriez - CHU de Lille, Lille, Nord

Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu, Nantes, Pays-de-la-Loire

Centre Hospitalier Lyon Sud, Pierre-Bénite, Rhône

Henri Mondor Hospital, Créteil, Val-de-Marne

Gustave Roussy, Villejuif, Val-de-Marne

Local Institution - 0029, Poitiers, Vienne

Hôpital Saint-Louis, Paris, Not set

Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE, Toulouse, Not set

Hôpital Saint Antoine, Paris, Île-de-France

Local Institution - 0072, Heidelberg, Baden-Württemberg

Local Institution - 0078, Ulm, Baden-Württemberg

Local Institution - 0077, Nuremberg, Bayern

Local Institution - 0073, Köln, Nordrhein-Westfalen

Local Institution - 0079, Dresden, Sachsen

Local Institution - 0087, Leipzig, Sachsen

Local Institution - 0075, Kiel, Schleswig-Holstein

Local Institution - 0115, Essen, Not set

Local Institution - 0076, Hamburg, Not set

Local Institution - 0074, Wuerzburg, Not set

University Hospital of Patras, Patras, Achaḯa

Evangelismos General Hospital of Athens, Athens, Attikí

Attikon General University Hospital, Chaidari, Attikí

G. Papanikolaou General Hospital, Thessaloniki, Thessaloníki

Local Institution - 0055, Be'er Sheva, HaDarom

Local Institution - 0058, Petah-Tikva, HaMerkaz

Sheba Medical Center, Ramat Gan, HaMerkaz

Sourasky Medical Center, Tel Aviv, Tell Abīb

Rambam Health Care Campus, Haifa, Not set

Hadassah Medical Center, Jerusalem, Not set

Humanitas, Rozzano, Milano

Local Institution - 0067, Torino, Piemonte

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola, Bologna, Not set

AOU Policlinico Umberto I, Roma, Not set

Nagoya City University Hospital, Nagoya, Aichi

Hokkaido University Hospital, Sapporo, Hokkaido

Hyogo Medical University Hospital, Nishinomiya, Hyogo

Kanazawa University Hospital, Kanazawa, Ishikawa

Tokai University Hospital, Isehara, Kanagawa

Chiba University Hospital, Chiba, Not set

Local Institution - 0054, Fukuoka, Not set

Okayama University Hospital, Okayama, Not set

Local Institution - 0071, Shimotsuke, Not set

Local Institution - 0050, Tokyo, Not set

Local Institution - 0041, Hwasun Gun, Jeonranamdo

Local Institution - 0039, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0040, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0038, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0043, Seoul, Seoul-teukbyeolsi [Seoul]

Oslo Universitetssykehus Rikshospitalet, Oslo, Not set

Centrum Onkologii Ziemi Lubelskiej, Lublin, Lubelskie

Samodzielny Publiczny Centralny Szpital Kliniczny w Warszawie, Warsaw, Mazowieckie

Instytut Hematologii i Transfuzjologii, Warsaw, Mazowieckie

Uniwersyteckie Centrum Kliniczne, Gdańsk, Not set

Uniwersytecki Szpital Kliniczny w Poznaniu, Poznań, Not set

Narodowy Instytut Onkologii - Oddzial w Gliwicach, Gliwice, Śląskie

Institutul Clinic Fundeni, Bucharest, Not set

Institut Català d'Oncologia (ICO) - Badalona, Badalona, Barcelona [Barcelona]

Institut Català d'Oncologia - L'Hospitalet, L'Hospitalet Del Llobregat, Barcelona [Barcelona]

Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]

Clinica Universidad de Navarra, Pamplona, Navarra

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca, Salamanca, Not set

Hospital Universitari i Politecnic La Fe, València, Not set

Local Institution - 0093, Birmingham, England

Local Institution - 0080, London, London, City Of

Local Institution - 0094, London, London, City Of

Local Institution - 0081, Glasgow, Not set

Conditions: Multiple Myeloma

Learn More ›

CART-BCMA/CS1 in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT05950113

Withdrawn

This phase I trial studies the side effects and how well CART-BCMA/CS1 works in treating patients with multiple myeloma (MM) that has come back (relapsed) or that does not respond to treatment (refractory). Chimeric antigen receptor (CAR) T-cell therapy is a type of treatment in which a patient's T cells (a type of immune system cell) are changed in the laboratory so they will attack cancer cells. T cells are taken from a patient's blood. Then the gene for a special receptor that binds to a cert... Read More

Gender:

ALL

Ages:

Between 18 years and 74 years

Trial Updated:

04/30/2024

Locations: Melanie Ayala Ceja, Los Angeles, California

Conditions: Recurrent Multiple Myeloma, Refractory Multiple Myeloma

Learn More ›

High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Sitagliptin for the Prevention of GVHD

NCT05895201

Withdrawn

This is an open label Phase I-II study to determine the safe doses of bortezomib, sitagliptin, and PTCy (Phase I) with expansion into a phase II trial to determine efficacy in improving survival.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/26/2024

Locations: Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana

Conditions: Bone Marrow Transplant Complications, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Adult, Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia

Learn More ›

Liver Transplantation With Tregs at UCSF

NCT03654040

Terminated

This is a single-center, prospective, open-label, non-randomized clinical trial exploring cellular therapy to facilitate immunosuppression withdrawal in liver transplant recipients.

Gender:

ALL

Ages:

Between 18 years and 70 years

Trial Updated:

04/22/2024

Locations: University of California, San Francisco, San Francisco, California

Conditions: Liver Transplant

Learn More ›

Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

NCT03860844

Terminated

Primary Objective: Evaluate the anti-leukemic activity of isatuximab in combination with standard chemotherapies in pediatric participants of ages 28 days to less than 18 years with Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Acute Myeloid Leukemia (AML) Secondary Objectives: * Safety and tolerability assessments * Assessment of infusion reactions (IRs) * Pharmacokinetics (PK) of isatuximab * Minimal residual disease * Overall response rate * Overall survival * Event free surviv... Read More

Gender:

ALL

Ages:

Between 28 days and 17 years

Trial Updated:

04/22/2024

Locations: Sarah Cannon Research Institute-Site Number:8400001, Nashville, Tennessee +40 locations

Sarah Cannon Research Institute-Site Number:8400001, Nashville, Tennessee

Children's Medical Center of Dallas-Site Number:8400002, Dallas, Texas

Investigational Site Number :0320002, Caba, Buenos Aires

Investigational Site Number :0320006, Capital Federal, Buenos Aires

Investigational Site Number :0320005, Buenos Aires, Not set

Investigational Site Number :0320004, Buenos Aires, Not set

Investigational Site Number :0760013, Curitiba, Paraná

Investigational Site Number :0760006, Curitiba, Paraná

Investigational Site Number :0760007, Porto Alegre, Rio Grande Do Sul

Investigational Site Number :0760010, Jau, São Paulo

Investigational Site Number :0760009, Ribeirao Preto, São Paulo

Investigational Site Number :0760001, Sao Paulo, São Paulo

Investigational Site Number :0760004, Sao Paulo, São Paulo

Investigational Site Number :2080001, Copenhagen, Not set

Investigational Site Number :2500002, Lille, Not set

Investigational Site Number :2500003, Lyon, Not set

Investigational Site Number :2500001, PARIS Cedex 12, Not set

Investigational Site Number :2500004, PARIS Cedex 19, Not set

Investigational Site Number :2760005, Erlangen, Not set

Investigational Site Number :2760003, Hamburg, Not set

Investigational Site Number :2760006, Münster, Not set

Investigational Site Number :3000001, Athens, Not set

Investigational Site Number :3480002, Budapest, Not set

Investigational Site Number :3800002, Genova, Liguria

Investigational Site Number :3800001, Monza, Lombardia

Investigational Site Number :3800003, Torino, Piemonte

Investigational Site Number :3800005, Verona, Veneto

Investigational Site Number :4100001, Seoul, Seoul-teukbyeolsi

Investigational Site Number :4100002, Seoul, Seoul-teukbyeolsi

Investigational Site Number :4100004, Seoul, Seoul-teukbyeolsi

Investigational Site Number :4840001, Monterrey, Nuevo León

Investigational Site Number :4840005, Col. Rancho Menchaca, Querétaro

Investigational Site Number :5280001, Utrecht, Not set

Investigational Site Number :5780001, Bergen, Not set

Investigational Site Number :5780002, Oslo, Not set

Investigational Site Number :6040001, Arequipa, Not set

Investigational Site Number :6040002, Lima, Not set

Investigational Site Number :6200002, Coimbra, Not set

Investigational Site Number :6200001, Lisboa, Not set

Investigational Site Number :6200003, Porto, Not set

Investigational Site Number :7520001, Göteborg, Not set

Conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia

Learn More ›

Study of Dexamethasone Plus IXAZOMIB (MLN9708) or Physicians Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis

NCT01659658

Terminated

The purpose of this study is to provide continued access of ixazomib and/or other study medications and to continue collecting relevant safety data to monitor participant's safety, determine whether dexamethasone plus IXAZOMIB improves hematologic response, 2-year vital organ (that is, heart or kidney) deterioration and mortality rate versus a physician's choice of a chemotherapy regimen in participants diagnosed with relapsed or refractory systemic light chain (AL) amyloidosis.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/19/2024

Locations: Cedars Sinai Medical Center, Los Angeles, California +65 locations

Cedars Sinai Medical Center, Los Angeles, California

University of Chicago, Chicago, Illinois

Indiana University School of Medicine, Indianapolis, Indiana

Tufts Medical Center, Boston, Massachusetts

Boston Medical Center, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Mayo Clinic, Rochester, Minnesota

Washington University, Saint Louis, Missouri

Columbia University Medical Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Cincinnati, Cincinnati, Ohio

Cleveland Clinic, Cleveland, Ohio

Vanderbilt University Medical Center, Nashville, Tennessee

University of Texas Southwestern Medical Center, Dallas, Texas

Froedtert and The Medical College of Wisconsin, Milwaukee, Wisconsin

Westmead Hospital, Westmead, New South Wales

Princess Alexandra Hospital, Woolloongabba, Queensland

Box Hill Hospital, Box Hill, Victoria

Sir Charles Gairdner Hospital, Nedlands, Western Australia

Centro de Pesquisas Oncologicas, Florianopolis, Santa Catarina

Hospital Universitario Clementino Fraga Filho (UFRJ), Rio de Janeiro, Not set

Irmandade Da Santa Casa de Misericordia de Sao Paulo, Sao Paulo, Not set

Hospital Israelita Albert Einstein, Sao Paulo, Not set

Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Not set

Tom Baker Cancer Centre, Calgary, Alberta

Cross Cancer Institute, Edmonton, Alberta

Vancouver General Hospital, Vancouver, British Columbia

Princess Margaret Hospital, Toronto, Ontario

Fakultni nemocnice Ostrava, Ostrava, Moravskoslezsk Kraj

Vseobecna fakultni nemocnice v Praze, Praha, Praha, Hlavni Mesto

Arhus Universitetshospital Arhus Sygehus, Aahus, Not set

Rigshospitalet, Copenhagen, Not set

Hotel Dieu, Nantes, Loire-Atlantique

Hopital Claude Huriez, Lille, Not set

Centre Hospitalier et Universitaire de Limoges, Limoges, Not set

Hopital Saint Louis, Paris, Not set

Hopital de Rangueil, Toulouse, Not set

Charite - Universitatsmedizin Berlin, Berlin, Not set

Universitatsklinikum Hamburg Eppendorf, Hamburg, Not set

Universitat Heidelberg, Heidelberg, Not set

University General Hospital of Patras, Patras, Achaia

Alexandra Hospital, Athens, Not set

Rambam Health Corporation, Haifa, Not set

Hadasit Medical Research Services and Development Ltd, Jerusalem, Not set

Meir Medical Center, Kfar Saba, Not set

Rabin Medical Center - PPDS, Petach Tikva, Not set

Chaim Sheba Medical Center, Ramat-Gan, Not set

Institute of Hematology "Seragnoli" University of Bologna, Bologna, Not set

Fondazione IRCCS Policlinico San Matteo di Pavia, Pavia, Not set

Gachon University Gil Medical Center, Incheon, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital at Yonsei University Health System - PPDS, Seoul, Not set

Samsung Medical Center - PPDS, Seoul, Not set

The Catholic University of Korea, Seoul St Mary's Hospital, Seoul, Not set

VU Medisch Centrum, Amsterdam, Noord-Holland

Maastricht University Medical Center, AZ Maastricht, Not set

Universitair Medisch Centrum Utrecht, Utrecht, Not set

Clinica Universidad de Navarra, Pamplona, Navarra

Hospital Clinic de Barcelona, Barcelona, Not set

Hospital Universitario de La Princesa, Madrid, Not set

Hospital Universitario Puerta de Hierro - Majadahonda, Majadahonda, Not set

Hospital Universitario de Salamanca, Salamanca, Not set

Queen Elizabeth Hospital, Birmingham, Not set

Royal Free and University College Medical School, London, Not set

Manchester Royal Infirmary, Manchester, Not set

Oxford University Hospitals NHS Trust, Oxford, Not set

Conditions: Relapsed or Refractory Systemic Light Chain Amyloidosis

Learn More ›

Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

NCT01783535

Active Not Recruiting

The primary objective of this protocol is to evaluate the response rate of bilateral disease participants who have at least one eye with advanced intra-ocular retinoblastoma (stratum B) using upfront therapy with chemotherapy delivered directly to the eye. The main biology objective is to improve our understanding of the biology and tumorigenesis (how tumor develops) of retinoblastoma when biology specimens are available. As clinicians, the primary goal of the investigators for children with ret... Read More

Gender:

ALL

Ages:

All

Trial Updated:

04/11/2024

Locations: St. Jude Children's Research Hospital, Memphis, Tennessee

Conditions: Retinoblastoma

Learn More ›

huJCAR014 CAR-T Cells in Treating Adult Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia

NCT03103971

Terminated

This phase I trial studies the side effects of huJCAR014 in treating patients with relapsed or refractory B-cell non-Hodgkin lymphoma or acute lymphoblastic leukemia. huJCAR014 CAR-T cells are made in the laboratory by genetically modifying a patient's T cells and may specifically kill cancer cells that have a molecule CD19 on their surfaces. In Stage 1, dose-finding studies will be conducted in 3 cohorts: 1. Aggressive B cell NHL 2. Low burden ALL 3. High burden ALL In Stage 2, studies may b... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/08/2024

Locations: Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington

Conditions: Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Refractory Adult Acute Lymphoblastic Leukemia, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Recurrent Transformed Non-Hodgkin Lymphoma, Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements, Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements, Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, Refractory B Acute Lymphoblastic Leukemia, Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements

Learn More ›

Brentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma

NCT01979536

Completed

This partially randomized phase II trial studies how well brentuximab vedotin or crizotinib and combination chemotherapy works in treating patients with newly diagnosed stage II-IV anaplastic large cell lymphoma. Brentuximab vedotin is a monoclonal antibody, called brentuximab, linked to a toxic agent called vedotin. Brentuximab attaches to CD30 positive cancer cells in targeted way and delivers vedotin to kill them. Crizotinib and methotrexate may stop the growth of cancer cells by blocking som... Read More

Gender:

ALL

Ages:

21 years and below

Trial Updated:

04/04/2024

Locations: Children's Hospital of Alabama, Birmingham, Alabama +153 locations

Children's Hospital of Alabama, Birmingham, Alabama

Phoenix Childrens Hospital, Phoenix, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Kaiser Permanente Downey Medical Center, Downey, California

City of Hope Comprehensive Cancer Center, Duarte, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Valley Children's Hospital, Madera, California

UCSF Benioff Children's Hospital Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

Sutter Medical Center Sacramento, Sacramento, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

Naval Medical Center -San Diego, San Diego, California

UCSF Medical Center-Parnassus, San Francisco, California

UCSF Medical Center-Mission Bay, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Orlando Health Cancer Institute, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Tampa General Hospital, Tampa, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Hospital, West Palm Beach, Florida

Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia

Augusta University Medical Center, Augusta, Georgia

Memorial Health University Medical Center, Savannah, Georgia

University of Hawaii Cancer Center, Honolulu, Hawaii

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Maine Children's Cancer Program, Scarborough, Maine

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Ascension Saint John Hospital, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids, Michigan

Beaumont Children's Hospital-Royal Oak, Royal Oak, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

Columbia Regional, Columbia, Missouri

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

University Medical Center of Southern Nevada, Las Vegas, Nevada

Sunrise Hospital and Medical Center, Las Vegas, Nevada

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Summerlin Hospital Medical Center, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Morristown Medical Center, Morristown, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

NYU Winthrop Hospital, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

NYP/Weill Cornell Medical Center, New York, New York

University of Rochester, Rochester, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

Mission Hospital, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

Saint Jude Children's Research Hospital, Memphis, Tennessee

The Children's Hospital at TriStar Centennial, Nashville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

El Paso Children's Hospital, El Paso, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

Inova Fairfax Hospital, Falls Church, Virginia

Children's Hospital of The King's Daughters, Norfolk, Virginia

Naval Medical Center - Portsmouth, Portsmouth, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

University of Wisconsin Carbone Cancer Center, Madison, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Conditions: Anaplastic Large Cell Lymphoma, ALK-Positive, Ann Arbor Stage II Noncutaneous Childhood Anaplastic Large Cell Lymphoma, Ann Arbor Stage III Noncutaneous Childhood Anaplastic Large Cell Lymphoma, Ann Arbor Stage IV Noncutaneous Childhood Anaplastic Large Cell Lymphoma

Learn More ›

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

NCT05583149

Recruiting

This research is being done to assess the effectiveness and safety of acalabrutinib combined with lisocabtagene maraleucel (liso-cel) for people with relapsed/refractory aggressive B-cell lymphoma. This research study involves the study drug acalabrutinib in combination with lisocabtagene maraleuce

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/03/2024

Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations

Conditions: Refractory Aggressive B-cell Lymphomas, Refractory B-Cell Non-Hodgkin Lymphoma, Aggressive B-cell NHL, Diffuse Large B-cell Lymphoma (DLBCL), De Novo or Transformed Indolent B-cell Lymphoma, DLBCL, Nos Genetic Subtypes, T Cell/Histiocyte-rich Large B-cell Lymphoma, EBV-Positive DLBCL, Nos, Primary Mediastinal [Thymic] Large B-cell Lymphoma (PMBCL), High-Grade B-Cell Lymphoma, Nos, C-MYC/BCL6 Double-Hit High-Grade B-Cell Lymphoma, Grade 3b Follicular Lymphoma, C-MYC/BCL2 Double-Hit High-Grade B-Cell Lymphoma

Learn More ›

Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System

NCT00653068

Completed

This phase III trial studies the side effects of combination chemotherapy, 3-dimensional conformal radiation therapy, and an autologous peripheral blood stem cell transplant, and to see how well they work in treating young patients with atypical teratoid/rhabdoid tumor of the central nervous system. Giving high-dose chemotherapy before an autologous peripheral blood stem cell transplant stops the growth of cancer cells by stopping them from dividing or killing them. Giving colony-stimulating fac... Read More

Gender:

ALL

Ages:

21 years and below

Trial Updated:

04/03/2024

Locations: Children's Hospital of Alabama, Birmingham, Alabama +93 locations

Children's Hospital of Alabama, Birmingham, Alabama

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Kaiser Permanente Downey Medical Center, Downey, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Valley Children's Hospital, Madera, California

UCSF Benioff Children's Hospital Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Rady Children's Hospital - San Diego, San Diego, California

UCSF Medical Center-Parnassus, San Francisco, California

UCSF Medical Center-Mission Bay, San Francisco, California

Connecticut Children's Medical Center, Hartford, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Lee Memorial Health System, Fort Myers, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Nemours Children's Clinic - Orlando, Orlando, Florida

Orlando Health Cancer Institute, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Hospital, West Palm Beach, Florida

Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia

University of Hawaii Cancer Center, Honolulu, Hawaii

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Riley Hospital for Children, Indianapolis, Indiana

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Tulane University School of Medicine, New Orleans, Louisiana

Children's Hospital New Orleans, New Orleans, Louisiana

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Dana-Farber Cancer Institute, Boston, Massachusetts

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

Hackensack University Medical Center, Hackensack, New Jersey

Morristown Medical Center, Morristown, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Overlook Hospital, Summit, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Montefiore Medical Center - Moses Campus, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Rochester, Rochester, New York

New York Medical College, Valhalla, New York

Mission Hospital, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

Mercy Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Greenville Cancer Treatment Center, Greenville, South Carolina

East Tennessee Childrens Hospital, Knoxville, Tennessee

Driscoll Children's Hospital, Corpus Christi, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Primary Children's Hospital, Salt Lake City, Utah

Seattle Children's Hospital, Seattle, Washington

West Virginia University Charleston Division, Charleston, West Virginia

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Royal Children's Hospital, Parkville, Victoria

Princess Margaret Hospital for Children, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Kingston Health Sciences Centre, Kingston, Ontario

Hospital for Sick Children, Toronto, Ontario

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor

Learn More ›

Browse by State

Cyclophosphamide treatment options in Alabama

Cyclophosphamide treatment options in Alaska

Cyclophosphamide treatment options in Arizona

Cyclophosphamide treatment options in Arkansas

Cyclophosphamide treatment options in California

Cyclophosphamide treatment options in Colorado

Cyclophosphamide treatment options in Connecticut

Cyclophosphamide treatment options in Delaware

Cyclophosphamide treatment options in District of Columbia

Cyclophosphamide treatment options in Florida

Cyclophosphamide treatment options in Georgia

Cyclophosphamide treatment options in Hawaii

Cyclophosphamide treatment options in Idaho

Cyclophosphamide treatment options in Illinois

Cyclophosphamide treatment options in Indiana

Cyclophosphamide treatment options in Iowa

Cyclophosphamide treatment options in Kansas

Cyclophosphamide treatment options in Kentucky

Cyclophosphamide treatment options in Louisiana

Cyclophosphamide treatment options in Maine

Cyclophosphamide treatment options in Montana

Cyclophosphamide treatment options in Nebraska

Cyclophosphamide treatment options in Nevada

Cyclophosphamide treatment options in New Hampshire

Cyclophosphamide treatment options in New Jersey

Cyclophosphamide treatment options in New Mexico

Cyclophosphamide treatment options in New York

Cyclophosphamide treatment options in North Carolina

Cyclophosphamide treatment options in North Dakota

Cyclophosphamide treatment options in Ohio

Cyclophosphamide treatment options in Oklahoma

Cyclophosphamide treatment options in Oregon

Cyclophosphamide treatment options in Maryland

Cyclophosphamide treatment options in Massachusetts

Cyclophosphamide treatment options in Michigan

Cyclophosphamide treatment options in Minnesota

Cyclophosphamide treatment options in Mississippi

Cyclophosphamide treatment options in Missouri

Cyclophosphamide treatment options in Pennsylvania

Cyclophosphamide treatment options in Rhode Island

Cyclophosphamide treatment options in South Carolina

Cyclophosphamide treatment options in South Dakota

Cyclophosphamide treatment options in Tennessee

Cyclophosphamide treatment options in Texas

Cyclophosphamide treatment options in Utah

Cyclophosphamide treatment options in Vermont

Cyclophosphamide treatment options in Virginia

Cyclophosphamide treatment options in Washington

Cyclophosphamide treatment options in West Virginia

Cyclophosphamide treatment options in Wisconsin

Cyclophosphamide treatment options in Wyoming