Retrospective Study in Patients Receiving Two or More OZURDEX® Injections for Retinal Vein Occlusion (RVO)
Completed
This is a retrospective data collection study to evaluate the efficacy, safety, and re-injection interval of OZURDEX® in the treatment of macular edema due to RVO. Following informed consent, there were no patient study visits. All data was collected via chart review.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2013
Locations: Not set, San Antonio, Texas
Conditions: Retinal Vein Occlusion, Macular Edema
Palonosetron in Sarcoma Patients Receiving Chemotherapy With Adriamycin and Ifosfamide (AI)
Completed
The goal of this clinical research study is to compare 2 treatment schedules of Aloxi (palonosetron) in patients with sarcoma who are receiving chemotherapy with adriamycin and ifosfamide. The safety of the drug and schedules will be studied. The effect of palonosetron on patients' quality of life (QOL) will also be studied.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/19/2013
Locations: UT MD Anderson Cancer Center, Houston, Texas
Conditions: Sarcoma, Nausea, Vomiting
Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia
Completed
Phase II trial to study the effectiveness of radiation therapy following chemotherapy in treating children with CNS relapse from acute lymphoblastic leukemia. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with radiation therapy may kill more cancer cells.
Gender:
ALL
Ages:
20 years and below
Trial Updated:
01/31/2013
Locations: Medical City Dallas Hospital, Dallas, Texas +5 locations
Conditions: Leukemia
Phase 2 Study of ET-743 (Trabectedin) in Patients With Persistent or Recurrent Endometrial Carcinoma
Completed
The purpose of this is to test the safety and effectiveness of an investigational chemotherapy agent in patients with persistent or recurrent endometrial cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/07/2013
Locations: Not set, Dallas, Texas
Conditions: Endometrial Neoplasms, Uterine Neoplasms, Genital Neoplasms, Female Urogenital Neoplasms
A Phase II Study of Moxidex Ophthalmic Solution for Treatment of Marginal Corneal Infiltrates
Terminated
The purpose of the study is to determine whether Moxidex ophthalmic solution is safe and effective in treating marginal corneal infiltrates.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
12/03/2012
Locations: Contact Alcon Call Center at 1-888-451-3937, Fort Worth, Texas
Conditions: Corneal Infiltrates
Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia
Completed
The purpose of this study is to compare the effectiveness of two multi-agent chemotherapy regimens using different dosages of cytarabine to eliminate all detectable leukemia.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
11/02/2012
Locations: Cook Children's Medical Center, Fort Worth, Texas +2 locations
Conditions: Leukemia, Myelocytic, Acute
Intravenous And Oral Casopitant (GW679769) For The Prevention Of Chemotherapy Induced Nausea And Vomiting
Completed
This is a Phase III trial designed to demonstrate that casopitant (GW679769) plus dexamethasone and ondansetron is more effective in the prevention of vomiting than dexamethasone and ondansetron alone following the administration of moderately emetogenic chemotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/06/2012
Locations: GSK Investigational Site, Corpus Christi, Texas +3 locations
Conditions: Vomiting, Nausea, Nausea and Vomiting, Chemotherapy-Induced
Safety and Efficacy of Dexamethasone as Adjunctive Therapy to Ranibizumab in Subjects With Choroidal Neovascularization and Age-Related Macular Degeneration
Terminated
This study will evaluate the safety and efficacy of dexamethasone (OZURDEX®) as adjunctive therapy to ranibizumab (LUCENTIS®) compared with ranibizumab alone in the treatment of patients with choroidal neovascularization secondary to age-related macular degeneration
Gender:
ALL
Ages:
50 years and above
Trial Updated:
08/01/2012
Locations: Not set, Abilene, Texas
Conditions: Subfoveal Choroidal Neovascularization, Age-Related Maculopathy
Safety and Efficacy of a New Therapy as Adjunctive Therapy to Anti-vascular Endothelial Growth Factor (Anti-VEGF) in Subjects With Wet Age-Related Macular Degeneration (AMD)
Completed
The study will evaluate the safety and efficacy of the intravitreal dexamethasone implant as adjunctive therapy to Anti-VEGF treatment in the study eye of treatment naïve subjects with choroidal neovascularization secondary to age-related macular degeneration. Subjects will be followed for 26 weeks.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
08/01/2012
Locations: Not set, San Antonio, Texas
Conditions: Choroidal Neovascularization, Age-Related Maculopathy
Study of the Effects of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol on Hypothalamic-Pituitary-Adrenal (HPA) Axis
Completed
To demonstrate the effects of ciclesonide applied as a nasal aerosol and ciclesonide aqueous (AQ) nasal spray on hypothalamic-pituitary-adrenal axis.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
07/17/2012
Locations: Central Texas Health Research, New Braunfels, Texas +1 locations
Conditions: Perennial Allergic Rhinitis
A Bioequivalence Study of Tobradex AF
Completed
The purpose of the study is to determine the amount of study medication that moves from the front of the eye into the fluid at the front of the inside of the eye.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/02/2012
Locations: Contact Alcon for Trial Location(s), Fort Worth, Texas
Conditions: Cataract
Study of Augmented Hyper-CVAD in Acute Lymphoblastic Leukemia Salvage
Completed
The goal of this clinical research study is to learn if a special combination of chemotherapy drugs called "augmented hyper-CVAD chemotherapy" given over 6 to 8 months followed by monthly maintenance chemotherapy for one year can help to control acute lymphoblastic leukemia or lymphoblastic lymphoma. The safety of this therapy will also be studied.
Gender:
ALL
Ages:
All
Trial Updated:
02/17/2012
Locations: UT MD Anderson Cancer Center, Houston, Texas
Conditions: Acute Lymphoblastic Leukemia