Erlotinib (Tarceva) as a Single Agent or Intercalated With Combination Chemotherapy in Patients With EGFR Positive NSCLC
Completed
This will be the first prospective study where patients will be selected on the basis of two measures of the epidermal growth factor receptor (EGFR) pathway. The study will assess prospectively the efficacy of erlotinib as a single agent or intercalated with chemotherapy in highly selected patients with EGFR overexpression and/or EGFR amplification.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/06/2012
Locations: MD Anderson Cancer Ctr - Orlando, Orlando, Florida +1 locations
Conditions: Carcinoma, Non-Small-Cell Lung
Safety and Efficacy of Angiotech Vascular Wrap Paclitaxel-Eluting Mesh for Hemodialysis Vascular Access
Terminated
This is a multi-center clinical study in subjects requiring arteriovenous grafts in the upper extremity for hemodialysis access. All subjects will provide informed consent before undergoing any study procedures. The study will consist of multiple subject visits and telephone contacts during the 52 week study period. During the study period subjects must also maintain an appropriate hemodialysis schedule. IDE Number: G060250
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/13/2011
Locations: Florida Research Network, LLC, Gainsville, Florida +5 locations
Conditions: Kidney Diseases, ESRD
Liposome Entrapped Paclitaxel Easy to Use (LEP-ETU) in Patients With Advanced Cancer
Completed
The purpose of this study is to determine the highest dose of Liposome Entrapped Paclitaxel Easy to Use formulation (LEP-ETU) that can be safely administered by an intravenous infusion to patients with advanced cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/30/2011
Locations: H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida
Conditions: Neoplasm
A Study Using Intravenous Paxceed™ to Treat Patients With Rheumatoid Arthritis
Completed
Paxceed™ is being developed by Angiotech Pharmaceuticals, Inc. for the treatment of Rheumatoid Arthritis (RA). The main objective of this study is to determine the effectiveness of treatment with Paxceed™ in patients with RA. In RA, there is an increase in cell growth and changes in cell function. The active substance in Paxceed™, paclitaxel, has undergone clinical studies as a cancer chemotherapeutic agent and has demonstrated its usefulness as an agent that stops growth of cells and blocks cer... Read More
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
07/26/2008
Locations: Radiant Research, Daytona Beach, Florida +2 locations
Conditions: Rheumatoid Arthritis
PH 1 Evaluation Of Oral CI-1033 In Combination With Paclitaxel/ Carboplatin As 1st Line Chemotherapy In NSCLC Patients
Completed
The main purpose of this study is to evaluate the overall safety and maximum dose of CI 1033 in combination with paclitaxel and carboplatin in patients with NSCLC.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/06/2006
Locations: Pfizer Investigational Site, Tampa, Florida
Conditions: Carcinoma, Non-Small Cell Lung