Phase II Study of ZD6474 in Advanced NSCLC
Terminated
The goal of this clinical research study is to learn how the drug ZD6474 affects the amount of tumor cell death in the body and the amount of blood that can be supplied to the tumor. The safety of ZD6474 alone and when given with chemotherapy will be studied. In addition, the side effects and response to this treatment will also be studied.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/13/2016
Locations: University of Texas M.D.Anderson Cancer Center, Houston, Texas
Conditions: Lung Cancer
Paclitaxel and Carboplatin in Women With Malignant Mixed Mullerian Tumors (MMMT) of the Uterus
Completed
The goal of this clinical research study is to find out if the combination of paclitaxel and carboplatin chemotherapy can shrink or slow the growth of mixed mullerian tumors (MMMT) of the uterus.
Gender:
FEMALE
Ages:
All
Trial Updated:
04/05/2016
Locations: Lyndon Baines Johnson Hospital, Houston, Texas +1 locations
Conditions: Mixed Tumor, Mullerian
Tarceva Surgery for Resectable Stage IIIA(N2) and IIIB (T4 N2) Non-Small-Cell Lung Cancer
Terminated
The goal of this clinical research study is to learn about the safety and effectiveness of OSI-774 when combined with standard chemotherapy (carboplatin and paclitaxel) before surgery in the treatment of non-small cell lung cancer.
Gender:
ALL
Ages:
All
Trial Updated:
04/05/2016
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Lung Cancer
A Trial of Preoperative MM-121 With Paclitaxel in HER2-negative Breast Cancer
Completed
To demonstrate whether addition of MM-121 to paclitaxel is more effective than treatment with paclitaxel alone, when administered as part of the neoadjuvant treatment in Her2 negative locally advanced operable breast cancer patients.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/30/2016
Locations: Texas Oncology - Amarillo, Amarillo, Texas +13 locations
Conditions: ER Positive, Her2 Negative Breast Cancer Patients, Triple Negative Breast Cancer Patients
Efficacy and Safety Study of Xyotax to Treat Prostate Cancer
Completed
The purpose of this study is to determine whether Xyotax, a conjugate of the taxane drug paclitaxel, is effective in the treatment of prostate cancer that is no longer responsive to hormone therapy.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/15/2016
Locations: Baylor College of Medicine -Methodist Hospital, Houston, Texas
Conditions: Prostatic Neoplasms
Study of Abraxane Plus Hormonal Therapy as Initial Treatment of Unresectable or Metastatic Prostate Cancer
Terminated
The purpose of the clinical trial is to assess the clinical benefit as measured by time to tumor progression of Abraxane plus hormonal therapy when applied to previously untreated patients with unresectable or metastatic adenocarcinoma of the prostate, as well as to assess safety and tolerability of the study drug regimen and to evaluate secondary efficacy endpoints such as overall survival and duration of response.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/15/2016
Locations: Baylor College of Medicine - Methodist Hospital, Houston, Texas
Conditions: Prostatic Neoplasms
BAY 43-9006 in Previously Untreated Patients With Non-Small Cell Lung Cancer (NSCLC)
Completed
The goal of this study is to find the highest tolerable dose of BAY 43-9006 (sorafenib) and bevacizumab that can be given with paclitaxel and carboplatin in patients with non-small cell lung cancer (NSCLC). The safety and effectiveness of this drug combination will also be studied.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/09/2016
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Lung Cancer
Hepatic Arterial Infusion (HAI) of Abraxane
Completed
The goal of this clinical research study is find the highest tolerated dose of Abraxane (nab-paclitaxel) that can be given directly into the liver of patients with advanced cancer that has spread to the liver.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/04/2016
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Liver Cancer, Advanced Cancers, Solid Tumors
Genasense, Carboplatin, Paclitaxel (GCP) Combination in Uveal Melanoma
Terminated
The goal of this clinical research is to learn if the combination of Genasense (oblimersen), carboplatin, and paclitaxel (GCP) can help to control metastatic uveal melanoma. The safety of this combination will also be studied.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2016
Locations: UT MD Anderson Cancer Center, Houston, Texas
Conditions: Melanoma
Hepatic Arterial Infusion of Nab-Paclitaxel in Patients With Metastatic Melanoma in the Liver
Completed
The goal of this clinical research is to find the highest tolerable dose of Abraxane (nab-paclitaxel) when given directly to the area where the cancer is located. The safety of this drug will also be studied.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/25/2015
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Melanoma, Liver Metastasis
Study of Taxane/Carboplatin +/- Cetuximab as First-Line Treatment for Patients With Advanced/Metastatic Non-Small Cell Lung Cancer
Completed
The primary purpose of this clinical research study is to learn if patients treated with the combination of Taxane/Carboplatin plus Cetuximab (C/T/C) have a longer progression-free survival than patients treated with Taxane/Carboplatin (T/C) alone. The safety of this treatment will also be studied.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/24/2015
Locations: Local Institution, Amarillo, Texas +3 locations
Conditions: Non-Small-Cell Lung Carcinoma
HAI Abraxane With Gemcitabine and Bevacizumab
Completed
The goal of this clinical research study is to find the highest tolerable dose of Abraxane® (nab-paclitaxel) when given directly into the liver, in combination with Gemzar® (gemcitabine) and Avastin® (bevacizumab) when given by vein.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/16/2015
Locations: UT MD Anderson Cancer Center, Houston, Texas
Conditions: Advanced Cancers