Paclitaxel or Docetaxel in Treating Women With Advanced Breast Cancer
NCT00002662
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether paclitaxel is more effective than docetaxel for breast cancer. PURPOSE: Randomized phase III trial to study the effectiveness of paclitaxel or docetaxel in treating women with stage IIIB or metastatic breast cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/01/2013
Locations: Montclair Regional Cancer Center, Birmingham, Alabama +31 locations
Conditions: Breast Cancer
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A Study of Mapatumumab in Combination With Paclitaxel and Carboplatin in Subjects With Non-small Cell Lung Cancer
NCT00583830
Completed
The purpose of this study is to evaluate the efficacy (disease response) and safety of mapatumumab in combination with carboplatin and paclitaxel as first line therapy in subjects with advanced non-small cell lung cancer (NSCLC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2013
Locations: Birmingham Hematology and Oncology Associates, LLC, Birmingham, Alabama +32 locations
Conditions: Non Small Cell Lung Cancer
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Chemotherapeutic Agents in Brain/Breast
NCT00795678
Completed
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Lapatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as trastuzumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Studying s... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/31/2013
Locations: Memorial Sloan Kettering, New York, New York +1 locations
Conditions: Breast Cancer, Metastatic Cancer
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Combination Chemotherapy Followed by Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer
NCT00003111
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy with irinotecan and cisplatin followed by surgery in treating patients with stage IIIA non-small cell lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2013
Locations: Yale Comprehensive Cancer Center, New Haven, Connecticut
Conditions: Lung Cancer
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Abraxane/Bevacizumab
NCT01821859
Terminated
The protocol will study the effect of the combination of two drugs-Abraxane and Bevacizumab-on a subject's ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. This study drug combination will be given to subjects who have already been treated for their cancer with other chemotherapy, and now their cancer has become worse or has come back again. Neither one of these study drugs has been approved by the FDA for treatment in these three types of cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/18/2013
Locations: OHSU Knight Cancer Institute, Portland, Oregon
Conditions: Ovarian Cancer, Peritoneal Cancer
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3-AP Plus Cisplatin and Paclitaxel in Treating Patients With Advanced or Metastatic Cancer
NCT00016874
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combining 3-AP, cisplatin, and paclitaxel in treating patients who have advanced or metastatic cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2013
Locations: Albert Einstein Comprehensive Cancer Center, Bronx, New York +1 locations
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
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Combination Chemotherapy Plus Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Esophagus or Stomach
NCT00009880
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy and radiation therapy may kill more tumor cells. PURPOSE: Randomized phase II trial to compare the effectiveness of combination chemotherapy plus radiation therapy with and without fluorouracil in treating patients who have cancer of the esophagus or stomach.
Gender:
ALL
Ages:
All
Trial Updated:
07/17/2013
Locations: Mobile Infirmary Medical Center, Mobile, Alabama +65 locations
Conditions: Esophageal Cancer, Gastric Cancer
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A Trial of Paclitaxel and Bevacizumab vs. Gemcitabine, Paclitaxel, and Bevacizumab in Advanced Breast Cancer
NCT00320541
Completed
This study will compare the cancer response to both treatments for locally advanced or metastatic breast cancer
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/15/2013
Locations: For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Fayetteville, Arkansas +31 locations
Conditions: Breast Cancer
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A Phase II Safety and Tolerability Study of Bevacizumab When Added to Single-agent Chemotherapy to Treat Patient With Breast Cancer Metastatic to Brain
NCT00476827
Terminated
Our hypothesis is that this study design, in which bevacizumab is added to one of six single agent chemotherapies with proven activity in metastatic breast cancer, will result in regression or stabilization of this disease in a safe and tolerable manner.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/15/2013
Locations: Palm Beach Cancer Center Institute, West Palm Beach, Florida +3 locations
Conditions: Breast Cancer
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Combination Chemotherapy in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
NCT00054392
Withdrawn
RATIONALE: Drugs used in chemotherapy such as gemcitabine, carboplatin, and paclitaxel use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective in treating non-small cell lung cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of different combination chemotherapy regimens in treating patients who have stage IIIB, stage IV, or re... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2013
Locations: Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda, California +56 locations
Conditions: Lung Cancer
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Combination Chemotherapy With or Without Biological Therapy in Treating Patients With Refractory Solid Tumor or Lymphoma
NCT00005021
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug, giving the drugs in different ways, and combining biological therapy with chemotherapy may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of topotecan, paclitaxel, and carboplatin with or without filgrastim in treating patients who have advanced solid tumor or lymphoma that has not responded to standard therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2013
Locations: Fox Chase Cancer Center, Philadelphia, Pennsylvania
Conditions: Lymphoma, Small Intestine Cancer, Unspecified Adult Solid Tumor, Protocol Specific
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Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Thyroid Cancer
NCT00004089
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus radiation therapy in treating patients who have previously untreated anaplastic thyroid cancer.
Gender:
ALL
Ages:
Between 15 years and 80 years
Trial Updated:
07/09/2013
Locations: Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois +2 locations
Conditions: Head and Neck Cancer
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