A Study of Tirzepatide in Participants With Impaired Liver Function
Completed
The purpose of this study is to assess how fast tirzepatide gets into the blood stream and how long it takes the body to remove it in participants with impaired liver function compared to healthy participants. The study will last about two months and will include five visits to the study center.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
06/09/2022
Locations: Orlando Clinical Research Center, Orlando, Florida
Conditions: Hepatic Insufficiency
A Study of Tirzepatide (LY3298176) in Participants With Impaired Kidney Function
Completed
The purpose of this study is to assess how fast tirzepatide gets into the blood stream and how long it takes the body to remove it in participants with impaired kidney function compared to healthy participants.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
06/09/2022
Locations: Clinical Pharmacology of Miami, Miami, Florida +1 locations
Conditions: Renal Insufficiency, End Stage Renal Disease
A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes
Completed
The reason for this study is to compare the effect of the study drug tirzepatide to semaglutide on blood sugar levels in participants with type 2 diabetes. The study will last approximately 47 weeks and may include about 12 visits.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2022
Locations: Clinical Research of South Florida, Coral Gables, Florida +6 locations
Conditions: Type 2 Diabetes
A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk
Completed
The purpose of the trial is to assess the efficacy and safety of tirzepatide taken once a week to insulin glargine taken once daily in participants with type 2 diabetes and increased cardiovascular risk. The study will last about 108 weeks and may include up to 30 visits.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2022
Locations: ALL Medical Research, LLC, Cooper City, Florida +6 locations
Conditions: Type 2 Diabetes Mellitus
A Study of Tirzepatide (LY3298176) Versus Insulin Degludec in Participants With Type 2 Diabetes
Completed
The purpose of this study is to compare the effect of the study drug tirzepatide to insulin degludec on blood sugar levels in participants with type 2 diabetes. The study will last about 67 weeks and may include up to 22 visits.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2022
Locations: Indago Research & Health Center, Inc., Hialeah, Florida +3 locations
Conditions: Type 2 Diabetes Mellitus
A Study of Tirzepatide (LY3298176) Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine With or Without Metformin
Completed
The purpose of this study is to compare the safety and efficacy of the study drug tirzepatide to placebo in participants with type 2 diabetes that are already on insulin glargine, with or without metformin. Participants will administer tirzepatide or placebo along with their previous glucose lowering medications. The study will last approximately 47 weeks and may include about 23 visits.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/12/2021
Locations: Sun Coast Clinical Research, Inc, New Port Richey, Florida
Conditions: Type 2 Diabetes
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise Alone
Completed
The goal for this study is to evaluate the efficacy and safety of tirzepatide versus placebo in participants with type 2 diabetes not under control with diet and exercise alone. The study will last approximately 47 weeks and may include about 15 visits.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/18/2021
Locations: Clinical Research of South Florida, Coral Gables, Florida +4 locations
Conditions: Type 2 Diabetes Mellitus
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes
Completed
The purpose of this study is to determine the efficacy of tirzepatide in participants with type 2 diabetes.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/28/2021
Locations: Suncoast Research Group, LLC, Miami, Florida
Conditions: Type 2 Diabetes
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Mellitus
Completed
The purpose of this study is to evaluate the efficacy of the study drug tirzepatide in participants with type 2 diabetes mellitus.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/31/2019
Locations: Clinical Research of South Florida, Coral Gables, Florida +5 locations
Conditions: Type 2 Diabetes Mellitus