Chronic Lymphocytic Leukemia Clinical Trials in United Kingdom

A listing of 16 Chronic Lymphocytic Leukemia clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Chronic Lymphocytic Leukemia

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There are currently 16 active clinical trials seeking participants for Chronic Lymphocytic Leukemia research studies. The states with the highest number of trials for Chronic Lymphocytic Leukemia participants are .

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

NCT06588478

Recruiting

The main purpose of Part 1 of this study is to assess the efficacy and safety of 3 dose levels of Pirtobrutinib in participants with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), who have received 1-3 lines of treatment including a covalent Bruton tyrosine kinase (BTK) inhibitor. The purpose of Part 2 of this study is to evaluate pirtobrutinib monotherapy in participants with treatment-naïve CLL/SLL with 17p deletions. Participation in Part 1 is expected to last approxi... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/18/2025

Locations: Ironwood Cancer & Research Centers, Chandler, Arizona +135 locations

Ironwood Cancer & Research Centers, Chandler, Arizona

City of Hope National Medical Center, Duarte, California

City of Hope National Medical Center, Irvine, California

Palo Alto Medical Foundation Research Institute (PAMFRI), Palo Alto, California

Stanford Cancer Center, Palo Alto, California

Rocky Mountain Cancer Center, Aurora, Colorado

University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami, Florida

City of Hope National Medical Center, Atlanta Cancer Center, Newnan, Georgia

Mission Cancer + Blood, Waukee, Iowa

Saint Elizabeth Medical Center Edgewood, Edgewood, Kentucky

American Oncology Partners of Maryland, PA, Bethesda, Maryland

Boston Medical Center, Boston, Massachusetts

Gulfport Memorial Hospital, Gulfport, Mississippi

Comprehensive Cancer Centers of Nevada, Henderson, Nevada

Clinical Research Alliance, Westbury, New York

East Carolina University, Greenville, North Carolina

Williamette Valley Cancer Institute & Research Center, Eugene, Oregon

Cancer Care Associates Of York, York, Pennsylvania

The West Clinic, PLLC dba West Cancer Center, Germantown, Tennessee

USO-Texas Oncology-Central/South Texas, Austin, Texas

Sarah Cannon Research Institute/SCRI, The Woodlands, Texas

USO-Virginia Oncology Associates, Hampton, Virginia

USO-Northwest Cancer Specialists, PC, Vancouver, Washington

Bankstown-Lidcombe Hospital, Bankstown, New South Wales

Coffs Harbour Health Campus, Coffs Harbour, New South Wales

Calvary Mater Newcastle, Waratah, New South Wales

Princess Alexandra Hospital, Woolloongabba, Queensland

Flinders Medical Centre, Adelaide, South Australia

ICON Cancer Centre - Kurralta Park, Kurralta Park, South Australia

Royal Hobart Hospital, Hobart, Tasmania

Box Hill Hospital, Box Hill, Victoria

Latrobe Regional Health, Traralgon, Victoria

The Perth Blood Institute - West Perth, West Perth, Western Australia

Clinique Saint Pierre, Ottignies, Brabant Wallon

Institut Jules Bordet, Anderlecht, Bruxelles-Capitale, Région De

Groupe Jolimont, La Louvière, Hainaut

CHR Verviers - La Tourelle, Verviers, Liège

UZ Gent, Gent, Oost-Vlaanderen

AZ Nikolaas, Sint-Niklaas, Oost-Vlaanderen

UZ Leuven, Leuven, Vlaams-Brabant

AZ Sint-Jan Brugge-Oostende AV, Brugge, West-Vlaanderen

AZ Delta vzw, Roeselare, West-Vlaanderen

Royal Victoria Regional Health Centre, Barrie, Ontario

CIUSSS- saguenay-Lac-Saint-Jean, Chicoutimi, Quebec

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Fakultní nemocnice Brno Bohunice, Brno, Brno-město

Fakultni nemocnice Hradec Kralove, Hradec Kralove, Hradec Králové

Fakultni nemocnice Kralovske Vinohrady, PRague, Praha 10

Vseobecna fakultni nemocnice v Praze, Praha 2, Not set

Aarhus Universitetshospital, Skejby, Aarhus, Midtjylland

Odense Universitetshospital, Odense, Syddanmark

Centre Antoine-Lacassagne, Nice, Alpes-Maritimes

Groupe Hospitalier de la Région de Mulhouse et Sud Alsace - Hôpital Emile Muller, Mulhouse, Alsace

Centre Hospitalier Universitaire de Caen - Hôpital Côte de Nacre, Caen, Calvados

Centre Hospitalier Régional Universitaire de Tours - Hôpital Bretonneau, Tours, Indre-et-Loire

Centre Hospitalier du Mans, Le Mans, Sarthe

Centre Hospitalier d'Argenteuil Victor Dupouy, Argenteuil, Val-d'Oise

Klinikum Aschaffenburg-Alzenau, Aschaffenburg, Bayern

Centrum für Hämatologie und Onkologie Bethanien, Frankfurt, Hessen

OSP Göttingen, Goettingen, Niedersachsen

Onkologisches Ambulanzzentrum Hannover, Hannover, Niedersachsen

MV-Zentrum für Onkologie und Hämatologie, Cologne, Nordrhein-Westfalen

InVO Institut für Versorgungsforschung in der Onkologie, Koblenz, Rheinland-Pfalz

Evangelismos General Hospital of Athens, Athens, Attikí

Attikon General University Hospital, Chaidari, Attikí

General Hospital of Athens "Laiko", Αthens, Attikí

G. Papanikolaou General Hospital, Thessaloniki, Thessaloníki

Pécsi Tudományegyetem Klinikai Központ, Pécs, Baranya

Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ, Szeged, Csongrád

Semmelweis Egyetem, Budapest, Not set

Dél-Pesti Centrumkórház, Budapest, Not set

Azienda Ospedaliero Universitaria S.Anna, Cona, Emilia-Romagna

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore, Roma, Lazio

ASST Grande Ospedale Metropolitano Niguarda, Milan, Lombardia

A.O.U.C. Policlinico di Bari, Bari, Puglia

Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO, Palermo, Sicilia

Azienda Ospedaliera Universitaria Careggi, Firenze, Toscana

AO Santa Maria della Misericordia, Perugia, Umbria

Azienda Ospedale - Università Padova, Padova, Veneto

Azienda Ospedaliero Universitaria Maggiore della Carità, Novara, Not set

AOU Policlinico Umberto I, Roma, Not set

Chonnam National University Hwasun Hospital, Hwasun-gun, Jeonranamdo

Pusan National University Hospital, Busan, Pusan-Kwangyǒkshi

Seoul National University Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

Samsung Medical Center, Seoul, Seoul-teukbyeolsi [Seoul]

The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu, Wrocław, Dolnośląskie

IN VIVO, Bydgoszcz, Kujawsko-pomorskie

Pratia MCM Krakow, Kraków, Małopolskie

AIDPORT Sp. z o.o., Skórzewo, Wielkopolskie

Pratia Onkologia Katowice, Katowice, Śląskie

Fundeni Clinical Institute, Bucuresti, București

Ovidius Clinical Hospital OCH, Ovidiu, Constanța

Spitalul Clinic Municipal Filantropia Craiova, Craiova, Dolj

Spitalul Clinic Colțea, București, Not set

Institutul Oncologic Cluj, Cluj, Not set

Institutul Regional de Oncologie, Iași, Not set

Fakultna nemocnica s poliklinikou F.D.Roosevelta Banska Bystrica, Banska Bystrica, Banskobystrický Kraj

Narodny onkologicky ustav, Bratislava, Bratislavský Kraj

Univerzitna Nemocnica L. Pasteura Kosice, Kosice, Košický Kraj

Univerzitna nemocnica Martin, Martin, Žilinský Kraj

Hospital Universitario Virgen Macarena, Sevilla, Andalucía

Hospital Universitario Central de Asturias, Oviedo, Asturias

Institut Català d'Oncologia (ICO) - Badalona, Badalona, Barcelona [Barcelona]

Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]

Institut Català d'Oncologia - L'Hospitalet, L'Hospitalet Del Llobregat, Barcelona [Barcelona]

Hospital Universitario Marqués de Valdecilla, Santander, Cantabria

Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]

Clinica Universidad de Navarra, Madrid, Madrid, Comunidad De

Hospital Universitario Infanta Leonor, Madrid, Madrid, Comunidad De

MD Anderson Cancer Center, Madrid, Madrid, Comunidad De

Hospital Universitario Ramón y Cajal, Madrid, Madrid, Comunidad De

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid, Comunidad De

Hospital Costa del Sol, Marbella, Málaga

Hospital Universitario Quironsalud Madrid, Madrid, Not set

Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca, Salamanca, Not set

Hospital Universitario Virgen Del Rocio, Sevilla, Not set

Kocaeli Üniversitesi, Izmit, Kocaeli

Sakarya University School of Medicine, Adapazarı, Sakarya

Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi, Ankara, Not set

Ankara University Health Practice and Research Hospitals, Ankara, Not set

Memorial Antalya Hospital, Antalya, Not set

Yeditepe Üniversitesi Koşuyolu Hastanesi, Istanbul, Not set

Ege Universitesi Hastanesi, Izmir, Not set

VM Medical Park Mersin Hastanesi, Mersin, Not set

Ondokuz Mayıs Universitesi, Samsun, Not set

Maidstone Hospital, Maidstone, Kent

Lincoln County Hospital, Lincoln, Lincolnshire

Northwick Park Hospital, Harrow, London, City Of

Hammersmith Hospital, London, London, City Of

Heartlands Hospital, Birmingham, Not set

The Beatson West of Scotland Cancer Centre, Glasgow, Not set

St James's University Hospital, Leeds, Not set

Clatterbridge Cancer Centre - Liverpool, Liverpool, Not set

Singleton Hospital, Swansea, Not set

Conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

Learn More ›

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

NCT06876662

Recruiting

Study J2N-MC-JZ01 (JZ01) is an individual-study appendix (ISA) under master protocol J2N-MC-JZNY, and represents participants from the completed originator study, clinical study LOXO-BTK-18001/J2N-OX-JZNA. Participants in the originator study will have the opportunity to continue their assigned study intervention or continue their follow-up visits by transitioning to this study. This study will evaluate the long-term safety and efficacy of pirtobrutinib.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/18/2025

Locations: Sylvester Comprehensive Cancer Center, Miami, Florida +35 locations

Sylvester Comprehensive Cancer Center, Miami, Florida

Florida Cancer Specialists, Sarasota, Florida

The Emory Clinic, Atlanta, Georgia

Northwestern University, Chicago, Illinois

Dana-Farber Cancer Institute, Boston, Massachusetts

Mayo Clinic- Minnesota, Rochester, Minnesota

University Of Nebraska Medical Center, Omaha, Nebraska

Cayuga Cancer Center, Ithaca, New York

Northwell Health, Lake Success, New York

Memorial Sloan-Kettering Cancer Center (MSKCC) - New York, New York, New York

Duke University Medical Center, Durham, North Carolina

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

University of Pennsylvania Hospital, Philadelphia, Pennsylvania

Tennessee Oncology, Nashville, Tennessee

University of Texas MD Anderson Cancer Center, Houston, Texas

Swedish Cancer Institute, Seattle, Washington

Medical College of Wisconsin, Milwaukee, Wisconsin

Flinders Medical Centre, Adelaide, South Australia

Peter MacCallum Cancer Centre, Melbourne, Victoria

Linear Clinical Research, Victoria, Not set

CHU de Nantes - Hotel Dieu, Nantes Cedex 1, Loire Atlantique

IRCCS-AOU di Bologna-Policlinico S.Orsola-Malpighi, Bologna, Not set

Ospedale San Raffaele, Milano, Not set

Tokai University Hospital- Isehara Campus, Isehara, Kanagawa

National Cancer Center Hospital, Cho-ku, Tokyo

Nagoya Medical Center, Aichi-Ken, Not set

National Hospital Organization Kyushu Cancer Center, Fukuoka, Not set

Tohoku University Hospital, Miyagi-Ken, Not set

Hokkaido University Hospital, Sapporoshi, Not set

Seoul National University Hospital, Seoul, Korea

Pratia MCM Krakow, Krakow, Not set

Instytut Hermatologii I Transfuzjologii, Warszawa, Not set

Derriford Hospital, Plymouth, Devon

Churchill Hospital, Oxford, Oxfordshire

St James's University Hospital, Leeds, West Yorkshire

Conditions: Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma

Learn More ›

Investigating the Role of Energy Balance Modification on Health Responses in Chronic Lymphocytic Leukaemia

NCT06379282

Recruiting

This randomised control clinical trial aims to investigate the effects of exercise training and diet on physical and functional fitness and immunological and metabolic changes in adults with chronic lymphocytic leukaemia. Investigators will randomise participants to either 12 weeks of supervised/semi-supervised exercise only, exercise + nutritional guidance, or no exercise.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/23/2024

Locations: University of Surrey, Guildford, Not set

Conditions: Chronic Lymphocytic Leukemia, Frailty, Muscle Function, Immune Function, Lipid Cell; Tumor

Learn More ›

Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL

NCT05211856

Recruiting

The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination with venetoclax with and without obinutuzumab compared to chemoimmunotherapy in subjects with previously untreated CLL.

Gender:

All

Ages:

Between 18 years and 130 years

Trial Updated:

01/14/2022

Locations: Research Site, Fountain Valley, California +277 locations

Research Site, Fountain Valley, California

Research Site, Fullerton, California

Research Site, La Jolla, California

Research Site, Los Angeles, California

Research Site, Redondo Beach, California

Research Site, Santa Barbara, California

Research Site, Hartford, Connecticut

Research Site, Orlando, Florida

Research Site, Chicago, Illinois

Research Site, Fort Wayne, Indiana

Research Site, Wichita, Kansas

Research Site, Louisville, Kentucky

Research Site, New Orleans, Louisiana

Research Site, Scarborough, Maine

Research Site, Baltimore, Maryland

Research Site, Boston, Massachusetts

Research Site, Worcester, Massachusetts

Research Site, Brick, New Jersey

Research Site, Florham Park, New Jersey

Research Site, New York, New York

Research Site, Charlotte, North Carolina

Research Site, Canton, Ohio

Research Site, Pittsburgh, Pennsylvania

Research Site, Fort Sam Houston, Texas

Research Site, Seattle, Washington

Research Site, Spokane, Washington

Research Site, Tacoma, Washington

Research Site, Madison, Wisconsin

Research Site, Buenos Aires, Not set

Research Site, Capital Federal, Not set

Research Site, Ciudad Autonoma Buenos Aires, Not set

Research Site, Córdoba, Not set

Research Site, Rosario, Not set

Research Site, Adelaide, Not set

Research Site, Darlinghurst, Not set

Research Site, Heidelberg, Not set

Research Site, Kogarah, Not set

Research Site, Melbourne, Not set

Research Site, Nedlands, Not set

Research Site, Perth, Not set

Research Site, South Brisbane, Not set

Research Site, Waratah, Not set

Research Site, Woolloongabba, Not set

Research Site, Graz, Not set

Research Site, Krems, Not set

Research Site, Linz, Not set

Research Site, Salzburg, Not set

Research Site, Vienna, Not set

Research Site, Antwerpen, Not set

Research Site, Kortrijk, Not set

Research Site, Yvoir, Not set

Research Site, Curitiba, Not set

Research Site, Goiania, Not set

Research Site, Porto Alegre, Not set

Research Site, Rio de Janeiro, Not set

Research Site, Sao Paulo, Not set

Research Site, São José do Rio Preto, Not set

Research Site, São Paulo, Not set

Research Site, Pleven, Not set

Research Site, Plovdiv, Not set

Research Site, Sofia, Not set

Research Site, Vratsa, Not set

Research Site, Calgary, Alberta

Research Site, Edmonton, Alberta

Research Site, Vancouver, British Columbia

Research Site, Ottawa, Ontario

Research Site, Toronto, Ontario

Research Site, Montreal, Quebec

Research Site, Quebec, Not set

Research Site, Beijing, Not set

Research Site, Changchun, Not set

Research Site, Changsha, Not set

Research Site, Chengdu, Not set

Research Site, Chongqing, Not set

Research Site, Dalian, Not set

Research Site, Fuzhou, Not set

Research Site, Guangzhou, Not set

Research Site, Haikou, Not set

Research Site, Hangzhou, Not set

Research Site, Jinan, Not set

Research Site, Lanzhou, Not set

Research Site, Nanchang, Not set

Research Site, Nanjing, Not set

Research Site, Shanghai, Not set

Research Site, Shenyang, Not set

Research Site, Shenzhen, Not set

Research Site, Tianjin, Not set

Research Site, Urumchi, Not set

Research Site, Wenzhou, Not set

Research Site, Wuhan, Not set

Research Site, Xian, Not set

Research Site, Zhengzhou, Not set

Research Site, Brno, Not set

Research Site, Hradec Kralove, Not set

Research Site, Olomouc, Not set

Research Site, Ostrava, Not set

Research Site, Plzen, Not set

Research Site, Praha 1, Not set

Research Site, Praha, Not set

Research Site, Aarhus, Not set

Research Site, Herlev, Not set

Research Site, København Ø, Not set

Research Site, Odense C, Not set

Research Site, Roskilde, Not set

Research Site, Marseille, Not set

Research Site, Montpellier Cedex 5, Not set

Research Site, Paris Cedex 10, Not set

Research Site, Paris, Not set

Research Site, Pessac, Not set

Research Site, Pierre Benite, Not set

Research Site, Rennes Cedex 9, Not set

Research Site, Rouen Cedex 1, Not set

Research Site, Toulouse Cedex 9, Not set

Research Site, Villejuif, Not set

Research Site, Erlangen, Not set

Research Site, Hamburg, Not set

Research Site, Kempten, Not set

Research Site, Köln, Not set

Research Site, Paderborn, Not set

Research Site, Potsdam, Not set

Research Site, Ulm, Not set

Research Site, Würzburg, Not set

Research Site, Budapest, Not set

Research Site, Debrecen, Not set

Research Site, Kaposvár, Not set

Research Site, Pécs, Not set

Research Site, Szeged, Not set

Research Site, Haifa, Not set

Research Site, Jerusalem, Not set

Research Site, Petah Tiqva, Not set

Research Site, Tel Aviv, Not set

Research Site, Tel Hashomer, Not set

Research Site, Brescia, Not set

Research Site, Cagliari, Not set

Research Site, Meldola, Not set

Research Site, Milano, Not set

Research Site, Novara, Not set

Research Site, Palermo, Not set

Research Site, Ravenna, Not set

Research Site, Roma, Not set

Research Site, Torino, Not set

Research Site, Incheon, Not set

Research Site, Seoul, Not set

Research Site, Ulsan, Not set

Research Site, D.F, Not set

Research Site, Mexico City, Not set

Research Site, Mexico, Not set

Research Site, Monterrey, Not set

Research Site, Morelia, Not set

Research Site, Alkmaar, Not set

Research Site, Almere, Not set

Research Site, Amsterdam, Not set

Research Site, Arnhem, Not set

Research Site, Breda, Not set

Research Site, Den Bosch, Not set

Research Site, Dordrecht, Not set

Research Site, Nieuwegein, Not set

Research Site, Rotterdam, Not set

Research Site, Utrecht, Not set

Research Site, Callao, Not set

Research Site, Lima, Not set

Research Site, Brzozów, Not set

Research Site, Bydgoszcz, Not set

Research Site, Gdańsk, Not set

Research Site, Gdynia, Not set

Research Site, Kraków, Not set

Research Site, Lublin, Not set

Research Site, Wrocław, Not set

Research Site, Łódź, Not set

Research Site, Moscow, Not set

Research Site, Nizhny Novgorod, Not set

Research Site, Novosibirsk, Not set

Research Site, Ryazan, Not set

Research Site, Saint Petersburg, Not set

Research Site, Saint-Petersburg, Not set

Research Site, Samara, Not set

Research Site, Sochi, Not set

Research Site, St Petersburg, Not set

Research Site, Tula, Not set

Research Site, Volgograd, Not set

Research Site, Dammam, Not set

Research Site, Jeddah, Not set

Research Site, Riyadh, Not set

Research Site, Bratislava, Not set

Research Site, Kosice, Not set

Research Site, Bloemfontein, Not set

Research Site, Cape Town, Not set

Research Site, Johannesburg, Not set

Research Site, Pretoria, Not set

Research Site, Randburg, Not set

Research Site, Badalona(Barcelona), Not set

Research Site, Barcelona, Not set

Research Site, Madrid, Not set

Research Site, Majadahonda, Not set

Research Site, Salamanca, Not set

Research Site, Santander, Not set

Research Site, Valencia, Not set

Research Site, Göteborg, Not set

Research Site, Uppsala, Not set

Research Site, Örebro, Not set

Research Site, Kaohsiung, Not set

Research Site, Taichung, Not set

Research Site, Tainan City, Not set

Research Site, Taipei, Not set

Research Site, Taoyuan City, Not set

Research Site, Ankara, Not set

Research Site, Istanbul, Not set

Research Site, Izmir, Not set

Research Site, Kurupelit, Not set

Research Site, Talas, Not set

Research Site, Trabzon, Not set

Research Site, Cherkasy, Not set

Research Site, Dnipro, Not set

Research Site, Ivano-Frankivsk, Not set

Research Site, Kharkiv Region, Not set

Research Site, Khmelnytskyi, Not set

Research Site, Kyiv, Not set

Research Site, Zhytomyr, Not set

Research Site, Cambridge, Not set

Research Site, Canterbury, Not set

Research Site, Leeds, Not set

Research Site, Newcastle-Upon-Tyne, Not set

Research Site, Shrewsbury, Not set

Research Site, Wolverhampton, Not set

Conditions: Chronic Lymphocytic Leukemia

Learn More ›

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