There are currently 37 active clinical trials seeking participants for Prostate Cancer research studies. The states with the highest number of trials for Prostate Cancer participants are .
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
NCT05803941
Recruiting
The purpose of this post-marketing study is to further characterize the long-term outcome of known or potential risks of lutetium (177Lu) vipivotide tetraxetan also known as \[177Lu\]Lu-PSMA-617 or 177Lu-PSMA-617 and hereinafter referred to as AAA617. The study also seeks to further characterize (as possible) any other AAA617 causally related serious adverse event(s) in the long-term in adults with prostate cancer who received at least one dose of AAA617 from interventional, Phase I-IV Novartis... Read More
Gender:
MALE
Ages:
Between 18 years and 100 years
Trial Updated:
04/21/2025
Locations: Mayo Clinic Arizona, Scottsdale, Arizona +53 locations
Conditions: Prostate Cancer
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Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer
NCT06190899
Recruiting
This is a Phase 1/2, open-label, randomized, dose finding and dose expansion study to evaluate the safety, preliminary efficacy, and PK of gedatolisib in combination with darolutamide in subjects with mCRPC.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Barbara Ann Karmanos Cancer Institute, Detroit, Michigan +12 locations
Conditions: mCRPC (Metastatic Castration-resistant Prostate Cancer), Genital Diseases, Male, Urogenital Diseases, Male, Prostatic Disease, Prostatic Neoplasms, Castration-Resistant, Prostate Cancer
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In Vivo Dosimetry for Brachytherapy Study
NCT06863090
Recruiting
The main study aim is the investigate the clinical use of in vivo dosimeters (small measurement devices) for brachytherapy (internal radiotherapy).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2025
Locations: Mount Vernon Cancer Centre, Northwood, Middlesex
Conditions: Prostate Cancer, Gynaecological Cancer
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EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
NCT03987633
Recruiting
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the extent and basis of treatment failure in different patient populations. The vast majority of drug registration clinical trials have under-representation of ethnic minority populations. In addition, the wider Caucasian populations have reasonably different clinical characte... Read More
Gender:
ALL
Ages:
6 years and above
Trial Updated:
03/05/2025
Locations: Future Genetics, The Science Centre, Wolverhampton Science Park, Wolverhampton, West Midlands
Conditions: Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure, Hypertension, Peripheral Arterial Disease, Stroke, Ischemic, Asthma, Chronic Obstructive Pulmonary Disease, Obesity, Cancer, Chronic Kidney Diseases, Diabetes Mellitus, Dementia, Depression, Epilepsy, Mental Health Disorder, Rheumatoid Arthritis, Blood Pressure, Breast Cancer Risk, Prostate Cancer, Lung Cancers
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First-in-human Study of OVM-200 As a Therapeutic Cancer Vaccine
NCT05104515
Recruiting
OVM-200 will be tested in humans for the first time in Study OVM-200-100. Up to 52 patients aged 18-75 with prostate, lung or ovarian cancer will be enrolled in the Study to find out if OVM-200 is safe to continue studying it in patients with cancer. The Study consists of 2 parts: a dose escalation part and a dose expansion part. In the dose escalation part, up to 4 increasing doses of OVM-200 will be evaluated in small groups of cancer patients to find the recommended dose for the expansion par... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/12/2025
Locations: University College London Hospitals NHS Foundation Trust, London, Not set +3 locations
Conditions: Prostate Cancer, Non Small Cell Lung Cancer, Ovarian Cancer
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Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
NCT04557449
Recruiting
This is a Phase 1/2A, open label, multicenter, nonrandomized, multiple dose, safety, tolerability, pharmacokinetic and pharmacodynamic study of PF-07220060 administered as a single agent and then in combination with endocrine therapy. The study consists of two parts and a China and Japan monotherapy cohort. Part 1 includes dose escalation cohorts evaluating PF-07220060 as single agent or in combination with endocrine therapy or enzalutamide, as well as a food effect cohort and a DDI cohort Part... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/02/2025
Locations: Ellison Institute, Los Angeles, California +37 locations
Conditions: Liposarcoma, Prostate Cancer, Breast Neoplasms, Adenocarcinoma of Lung
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Imperial Prostate 9 - ATLAS (Approaches To Long-Term Active Surveillance)
NCT06280781
Recruiting
The goal of this intervention study is for patients on active surveillance for prostate cancer, to demonstrate that use of regular MRI scans is better able to detect cancer progression over 5 years compared to the current NICE defined strategy. Research Question P - In patients who are on active surveillance for low to medium risk prostate cancer, I - is the use of regular MRI scans C - compared to current NICE defined standard of care, O - better at detecting cancer progression with less cost... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
01/22/2025
Locations: Heatherwood Hospital, Ascot, Berkshire +2 locations
Conditions: Prostate Cancer
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Chronic Radiation Induced Bowel Toxicity Study
NCT06640959
Recruiting
In the UK over 22,000 people undergo pelvic radiotherapy treatment per year, for several types of cancers including prostate cancer. The investigators want to investigate whether there are any differences in the bacteria in the bowel in patients with prostate cancer and whether these change during treatment. The aim of this study is to analyse the bacteria from the stool of patients undergoing radiotherapy for prostate cancer. The investigators will also look for any changes in the urine, blood... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
12/19/2024
Locations: Christie NHS Foundation Trust, Manchester, Greater Manchester +1 locations
Conditions: Prostate Cancer
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The Remote Study: Investigating the Effects or Online Exercise on Quality of Life in Men With Prostate Cancer
NCT05989854
Recruiting
Currently, there are few opportunities for patients with cancer to have individual exercise guidance, and this has further been impacted by the Covid-19 pandemic. However, during the pandemic the use of virtual/remote platforms has been crucial in delivering care to cancer patients. The investigators think that remote exercise training may also offer a solution to support positive change in prostate cancer patients. As a result, the investigators have developed a remote/online exercise programme... Read More
Gender:
MALE
Ages:
Between 18 years and 99 years
Trial Updated:
12/12/2024
Locations: University of Surrey, Guildford, Surrey
Conditions: Prostate Cancer
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International Registry for Men With Advanced Prostate Cancer (IRONMAN)
NCT03151629
Recruiting
Our intent is to establish the International Registry to Improve Outcomes in Men with Advanced Prostate Cancer (IRONMAN) as a prospective, international cohort of minimum 5,000 men with advanced cancer, including men with mHSPC and M0/M1 CRPC. The goal is to establish a population-based registry and recruit patients across academic and community practices from Australia, Barbados, Brazil, Canada, Ireland, Jamaica, Kenya, Nigeria, Norway, Spain, South Africa, Sweden, Switzerland, the United Kingd... Read More
Gender:
MALE
Ages:
21 years and above
Trial Updated:
11/21/2024
Locations: University of Alabama-Birmingham, Birmingham, Alabama +120 locations
Conditions: Prostate Cancer
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ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer
NCT06579417
Recruiting
This is a multicenter, multinational trial to evaluate advanced MRI techniques for improved detection of clinically significant prostate cancer (csPCa). The study will enroll 500 participants at 5 clinical centers (100 participants per center). The current standard MRI technique for prostate cancer screening is multiparametric MRI (mpMRI), but two drawbacks include need for intravenous (IV) contrast and dependence on radiologist expertise. The investigators expect that the combination of two oth... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: University of California San Diego, San Diego, California +4 locations
Conditions: Prostate Cancer
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The Active Surveillance Study
NCT05810467
Recruiting
The Active Surveillance study is a prospective study developed to look at the association of biomarkers with PrCa presentation and progression among men on Active Surveillance and stratify it by their genetic risk. This study will also investigate the incidence and progression by differing genetic risks.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey
Conditions: Prostate Cancer
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