Cisplatin Treatment Options in United Kingdom

A collection of 298 research studies where Cisplatin is the interventional treatment. These studies are located in the United Kingdom . Cisplatin is used for conditions such as Head and Neck Cancer, Lung Cancer and Non-Small Cell Lung Cancer.

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A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110]

NCT02409342

Completed

This randomized, open-label study will evaluate the efficacy and safety of atezolizumab compared with chemotherapy consisting of a platinum agent (cisplatin or carboplatin per investigator discretion) combined with either pemetrexed (non-squamous disease) or gemcitabine (squamous disease) in programmed death-ligand 1 (PD-L1)-selected, chemotherapy-naive participants with Stage IV Non-Squamous or Squamous NSCLC.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

02/17/2023

Locations: University of California San Diego, La Jolla, California +141 locations

University of California San Diego, La Jolla, California

Yale Cancer Center, New Haven, Connecticut

Lynn Cancer Institute - West, Boca Raton, Florida

University of Maryland Greenebaum Cancer Center, Baltimore, Maryland

Oregon Health & Science Uni, Portland, Oregon

Sarah Cannon Cancer Center, Germantown, Tennessee

Vanderbilt University Medical Center; Multiple Sclerosis Center, Nashville, Tennessee

Hematology Oncology Associates of Fredericksburg, Inc., Fredericksburg, Virginia

VA Puget Sound Health Care Sys, Seattle, Washington

Oncovida*X, Salvador, BA

Centro de Pesquisas Clinicas em Oncologia - CPCO, Cachoeiro de Itapemirim, ES

Instituto Nacional de Cancer - INCa; Oncologia, Rio de Janeiro, RJ

Associacao Hospital de Caridade Ijui*X; Departamento De Oncologia, Ijui, RS

Hospital da Cidade de Passo Fundo; Centro de Pesquisa em Oncologia, Passo Fundo, RS

Santa Casa de Misericordia de Porto Alegre, Porto Alegre, RS

Hospital Sao Lucas - PUCRS, Porto Alegre, RS

Instituto Joinvilense de Hematologia E Oncologia, Joinville, SC

*X*Fundacao PIO XII, Barretos, SP

Hospital Santa Marcelina, Sao Paulo, SP

Instituto Do Câncer Do Estado de São Paulo Octávio Frias de Oliveira, São Paulo, SP

Harbin Medical University Tumor Hospital, Harbin City, Not set

CHU Angers, Angers, Not set

Hospital d Instructions des Armees Percy, Clamart, Not set

Hôpital Universitaire Dupuytren, Limoges, Not set

Clinique Clémentville, Montpellier, Not set

Centre D'oncologie de Gentilly, Nancy, Not set

Hopital Tenon, Paris, Not set

Centre Hospitalier Regional La Reunion Site Felix Guyon, Saint Denis Cedex, Not set

Hopital d'Instruction des Armees de Begin, Saint-Mande, Not set

Centre Hospitalier Regional Sud Reunion, Saint-pierre, Not set

Centre Paul Strauss, Strasbourg, Not set

Asklepios-Fachklinik Muenchen-Gauting; Klinik Für Pneumologie, Gauting, Not set

Pius-Hospital Oldenburg, Oldenburg, Not set

Sotiria Chest Hospital of Athens, Athens, Not set

IASO General Hospital of Athens, Athens, Not set

Metropolitan Hospital, Athens, Not set

Attikon University General Hospital, Chaidari, Not set

University General Hospital of Larissa, Larissa, Not set

University General Hospital of Patras, Patras, Not set

Thermi Clinic, Thermi, Thessaloniki, Not set

Bioclinic Thessaloniki, Thessaloniki, Not set

EUROMEDICA General Clinic of Thessaloniki; Gastroenterology Department, Thessaloniki, Not set

Papageorgiou General Hospital of Thessaloniki, Thessaloniki, Not set

Georgios Papanikolaou General Hosp. of Thessaloniki, Thessaloniki, Not set

Uzsoki Utcai Korhaz, Budapest, Not set

Szabolcs-Szatmar-Bereg Megyei; Korhazak es Egyetemi Oktatokorhaz, Nyiregyhaza, Not set

Pecsi Tudomanyegyetem, Pecs, Not set

Jasz-Nagykun-Szolnok Megyei Hetenyi Geza Korhaz-Rendelointezet; Megyei Onkologiai Kozpont, Szolnok, Not set

IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica, Meldola, Emilia-Romagna

Centro Di Riferimento Oncologico; Struttura Operativa Complessa Di Oncologia Medica B, Aviano, Friuli-Venezia Giulia

Asst Papa Giovanni XXIII, Bergamo, Lombardia

Azienda Ospedaliera Istituti Ospitalieri, Cremona, Lombardia

Ospedale San Raffaele S.r.l., Milano, Lombardia

Istituto Europeo Di Oncologia, Milano, Lombardia

Azienda Socio Sanitaria Territoriale ? ASST di Monza, Monza, Lombardia

Istituto Nazionale dei Tumori, Monza, Lombardia

Istituto Clinico Humanitas, Rozzano (MI), Lombardia

Azienda Ospedaliera Città della Salute e della Scienza di Torino, Torino, Piemonte

Azienda Ospedaliero-Universitaria ?PoliclinicoVittorio Emanuele?- P.O. G. Rodolico; Oncologia Medica, Catania, Sicilia

Azienda Ospedaliera Universitaria Integrata Verona; UOC Oncologia, Verona, Veneto

Aichi Cancer Center Hospital; Respiratory Medicine, Aichi, Not set

Nagoya University Hospital; Respiratory Medicine, Aichi, Not set

Kyushu University Hospital; Respiratory, Fukuoka, Not set

Hokkaido University Hospital, Hokkaido, Not set

Kobe City Medical Center General Hospital; Respiratory Medicine, Hyogo, Not set

Hyogo Cancer Center; Thoracic Oncology, Hyogo, Not set

Ibaraki Prefectural Central Hospital; Division of respiratory, Ibaraki, Not set

Sendai Kousei Hospital; Pulmonary Medicine, Miyagi, Not set

Okayama University Hospital; Respiratory and Allergy Medicine, Okayama, Not set

Osaka International Cancer Institute; Thoracic Oncology, Osaka, Not set

Kansai Medical university Hospital; Thoracic Oncology, Osaka, Not set

Osaka Habikino Medical Center, Osaka, Not set

National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai-shi, Not set

Saitama Cancer Center; Thoracic Oncology, Satima, Not set

National Cancer Center Hospital; Thoracic Medical Oncology, Tokyo, Not set

Tokyo Medical University Hospital; Dept of Surgery, Tokyo, Not set

Chonnam National University Hwasun Hospital, Jeollanam-do, Not set

Seoul National University Bundang Hospital, Seongnam-si, Not set

Kangbuk Samsung Hospital, Seoul, Not set

Uniwersyteckie Centrum Kliniczne, Gdansk, Not set

Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie; Oddzial onkologii z pododdzialem chemioterapii, Olsztyn, Not set

Mazowieckie Centrum Leczenia Chorob Pluc i Gruzlicy, Otwock, Not set

Wielkopolskie Centrum Pulmonologii i Torakochirurgii w Poznaniu, Poznan, Not set

Med-Polonia Sp. z o.o., Poznan, Not set

Teo Health SA - Saint Constantin Hospital, Brasov, Not set

Prof. Dr. I. Chiricuta Institute of Oncology, Cluj Napoca, Not set

Oncology Center Sf. Nectarie, Craiova, Not set

Institutul Regional de Oncologie Iasi; Clinica de Hematologie, Iasi, Not set

Sibiu Emergency Clinical County Hospital, Sibiu, Not set

Oncocenter Clinical Oncology, Timi?oara, Not set

Oncomed SRL, Timisoara, Not set

Arkhangelsk Regional Clinical Oncology Dispensary, Arkhangelsk, Arhangelsk

Federal State Institution Medical Radiology Research Center, Obninsk, Kaluga

Moscow City Oncology Hospital #62, Moscovskaya Oblast, Moskovskaja Oblast

Principal Military Clinical Hospital n.a. N.N. Burdenko, Moscow, Moskovskaja Oblast

Saint Petersburg Clinical Hospital of the Russian Academy of Sciences, St. Petersburg, Sankt Petersburg

Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic, Kazan, Tatarstan

Regional Clinical Oncology Center, Ryazan, Not set

Mordovia State University, Saransk, Not set

Leningrad Regional Clinical Hospital, St Petersburg, Not set

St. Petersburg Med Univ; n.a. I.P. Pavlov; Pulmonology Research, St Petersburg, Not set

Volgograd Regional Clinical Oncology Dispensary, Volgograd, Not set

Clinical Center of Serbia, Belgrade, Not set

Institute for Oncology and Radiology of Serbia; Medical Oncology, Belgrade, Not set

Clinical Center Kragujevac, Kragujevac, Not set

Institute of Lung Diseases Vojvodina, Sremska Kamenica, Not set

Hospital Universitari Germans Trias i Pujol; Servicio de Oncologia, Badalona, Barcelona

Consorcio Hospitalario Provincial de Castellon, Castellon DE LA Plana/castello DE LA Plana, Castellon

Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares

Hospital Son Llatzer, Palma de Mallorca, Islas Baleares

Hospital Universitario A Coruña, Coruna, LA Coruña

Hospital Universitario Cruces, Barakaldo, Vizcaya

Hospital del Mar, Barcelona, Not set

Hospital Universitario Vall d'Hebron - PPDS, Barcelona, Not set

Complejo Hospitalario de Jaen, Jaen, Not set

Hospital Clinico San Carlos; Servicio de Oncologia, Madrid, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Not set

Hosp Clinico Univ Lozano Blesa; División De Oncología Médica, Zaragoza, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Prince of Songkla University; Department Of Internal Medicine, Faculty Of Medicine, Hat Yai, Not set

Khon Kaen University, Khon Kaen, Not set

Chiang Rai Prachanukroh Hospital, Muang, Not set

Buddhachinnaraj Hospital, Phitsanulok, Not set

Cukurova University Medical Faculty Balcali Hospital, Adana, Not set

Hacettepe Universitesi Tip Fakultesi Hastanesi, Ankara, Not set

Istanbul University Cerrahpasa Medical Faculty, Istanbul, Not set

Ege Universitesi Tip Fakultesi Hastanesi, Izmir, Not set

Izmir Dr. Suat Seren Gogus Hastaliklari ve Cerrahisi Egitim ve Arastirma Hastanesi, Izmir, Not set

Inonu University Faculty of Medicine Turgut Ozal Medical Center, Malatya, Not set

Municipal Noncommercial Institution Regional Center of Oncology, Kharkiv, Kharkiv Governorate

Municipal Noncomercial Enterprise Odessa Regional Oncology Center ofthe Odessa StateAdministration, Odesa, Kherson Governorate

Municipal non profit enterprise of Sumy Regional Council Sumy Regional Clinical Oncology Disp, Sumy, Kholm Governorate

Communal Non-profit Enterprise City Clinical Hospital #4 of Dnipro City Council - PPDS; Chemotherapy, Dnipro, KIEV Governorate

Kyiv Railway Clinical Hospital #3 of Branch Health Center of the PJSC Ukrainian Railway, Kyiv, KIEV Governorate

Communal Nonprofit Enterprise Podilsky Regional Center Of Oncology OfTheVinnytsia Regional Council, Vinnytsia, KIEV Governorate

The Municipal Enterprise Volyn Regional Medical Oncology Centre of the Volyn Regional Council, Lutsk, Volhynian Governorate

Private Enterprise Private Manufacturing Company Acinus, Kirovograd, Not set

Birmingham Heartlands Hospital, Birmingham, Not set

Colchester General Hospital, Colchester, Essex, Not set

Christie Hospital, Manchester, Not set

Conditions: Non-Squamous Non-Small Cell Lung Cancer, Squamous Non-Small Cell Lung Cancer

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An Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026)

NCT02041533

Completed

The purpose of this study is to show that Nivolumab will improve progression free survival in subjects with strongly Stage IV or Recurrent PD-L1+ non-small cell lung cancer when compared to chemotherapy

Gender:

ALL

Ages:

18 years and above

Trial Updated:

02/02/2023

Locations: Southern Cancer Center, Inc., Mobile, Alabama +140 locations

Southern Cancer Center, Inc., Mobile, Alabama

Banner MD Anderson Cancer Center, Gilbert, Arizona

Local Institution - 0034, Tucson, Arizona

Local Institution - 0016, Stanford, California

University Of Colorado Hosp, Aurora, Colorado

Local Institution - 0020, New Haven, Connecticut

Local Institution - 0030, Miami, Florida

Local Institution - 0033, Ocala, Florida

H. Lee Moffitt Cancer Center, Tampa, Florida

Local Institution - 0010, Atlanta, Georgia

Northwest Georgia Oncology Center, P.C., Marietta, Georgia

Local Institution - 0037, Chicago, Illinois

Local Institution - 0014, Lexington, Kentucky

Crescent City Research Consortium, LLC, Marrero, Louisiana

Local Institution - 0024, Baltimore, Maryland

Local Institution - 0036, Boston, Massachusetts

Local Institution - 0070, Boston, Massachusetts

Roswell Park Cancer Institute, Buffalo, New York

Local Institution - 0009, New York, New York

Local Institution - 0005, New York, New York

University Of North Carolina At Chapel Hill, Chapel Hill, North Carolina

Local Institution - 0003, Durham, North Carolina

Local Institution - 0012, Cleveland, Ohio

Local Institution - 0027, Columbus, Ohio

Oregon Health & Science University, Portland, Oregon

Local Institution - 0007, Allentown, Pennsylvania

Local Institution - 0054, Philadelphia, Pennsylvania

Local Institution - 0002, Philadelphia, Pennsylvania

Local Institution - 0018, Pittsburgh, Pennsylvania

Local Institution - 0011, Charleston, South Carolina

Local Institution - 0038, Greenville, South Carolina

Local Institution - 0008, Nashville, Tennessee

Local Institution - 0006, Dallas, Texas

Local Institution - 0023, Houston, Texas

Cancer Centers of South Texas, San Antonio, Texas

Local Institution - 0029, Yakima, Washington

Local Institution - 0051, Berazategui, Buenos Aires

Local Institution - 0049, Capital Federal, Buenos Aires

Local Institution - 0052, Ciudad Autonoma De Buenos Aire, Buenos Aires

Local Institution - 0048, Cordoba, Not set

Local Institution - 0050, Cordoba, Not set

Local Institution - 0090, Camperdown, New South Wales

Local Institution - 0091, Brisbane, Queensland

Local Institution - 0071, Elizabeth Vale, South Australia

Local Institution - 0072, Fitzroy, Victoria

Local Institution - 0104, Heidelberg, Victoria

Local Institution - 0088, Wels, Not set

Local Institution - 0087, Wien, Not set

Local Institution - 0044, Brussels, Not set

Local Institution - 0055, Edegem, Not set

Local Institution - 0056, Gent, Not set

Local Institution - 0062, Leuven, Not set

Local Institution - 0134, Ijui, Rio Grande Do Sul

Local Institution - 0133, Porto Alegre, Rio Grande Do Sul

Local Institution - 0135, Barretos, Sao Paulo

Local Institution - 0086, Calgary, Alberta

Local Institution - 0115, Hamilton, Ontario

Local Institution - 0113, Toronto, Ontario

Local Institution - 0110, Montreal, Quebec

Local Institution - 0109, Rimouski, Quebec

Local Institution - 0059, Olomouc, Not set

Local Institution - 0061, Ostrava - Poruba, Not set

Local Institution - 0058, Praha 8, Not set

Local Institution - 0060, Usti nad Labem, Not set

Local Institution - 0120, Helsinki, Not set

Local Institution - 0119, Tampere, Not set

Local Institution - 0118, Vaasa, Not set

Local Institution - 0123, Caen, Not set

Local Institution - 0105, Lille, Not set

Local Institution - 0102, Marseille Cedex 20, Not set

Local Institution - 0167, Pontoise Cedex, Not set

Local Institution - 0100, Rennes Cedex 9, Not set

Local Institution - 0140, Strasbourg, Not set

Local Institution - 0074, Bamberg, Not set

Local Institution - 0065, Grosshansdorf, Not set

Local Institution - 0064, Heidelberg, Not set

Local Institution - 0063, Koeln, Not set

Local Institution - 0066, Stuttgart, Not set

Local Institution - 0092, Wiesbaden, Not set

Local Institution - 0073, Heraklion, Creta

Local Institution - 0075, Athens, Not set

Local Institution - 0126, Budapest, Not set

Local Institution - 0116, Debrecen, Not set

Local Institution - 0094, Matrahaza, Not set

Local Institution - 0084, Avellino, Not set

Local Institution - 0079, Livorno, Not set

Local Institution - 0143, Milano, Not set

Local Institution - 0142, Napoli, Not set

Local Institution - 0083, Perugia, Not set

Local Institution - 0082, Terni, Not set

Local Institution - 0161, Nagoya-shi, Aichi

Local Institution - 0146, Nagoya, Aichi

Local Institution - 0148, Matsuyama-shi, Ehime

Local Institution - 0153, Kobe City, Hyogo

Local Institution - 0144, Natori-shi, Miyagi

Local Institution - 0151, Niigata-shi, Niigata

Local Institution - 0166, Habikino-shi, Osaka

Local Institution - 0147, Miyakojima-ku, Osaka

Local Institution - 0145, Osaka-sayama, Osaka

Local Institution - 0152, Sakai, Osaka

Local Institution - 0150, Kitaadachi-gun, Saitama

Local Institution - 0149, Sunto-gun, Shizuoka

Local Institution - 0154, Chuo-ku, Tokyo

Local Institution - 0159, Akashi, Hyogo, Not set

Local Institution - 0162, Ota, Gunma, Not set

Local Institution - 0165, Sapporo, Hokkaido, Not set

Local Institution - 0160, Tokyo, Not set

Local Institution - 0158, Wakayama, Not set

Local Institution - 0155, Gangnam-gu, Not set

Local Institution - 0164, Seoul, Not set

Local Institution - 0163, Seoul, Not set

Local Institution - 0117, Mexico, Distrito Federal

Local Institution - 0122, Guadalajara, Jalisco

Local Institution - 0124, Merida, Yucatan

Local Institution - 0045, Amsterdam, Not set

Local Institution - 0057, Groningen, Not set

Local Institution - 0046, Rotterdam, Not set

Local Institution - 0114, Bydgoszcz, Not set

Local Institution - 0131, Krakow, Not set

Local Institution - 0139, Lodz, Not set

Local Institution - 0089, Warszawa, Not set

Local Institution - 0093, Wodzislaw Slaski, Not set

Local Institution - 0068, Cluj Napoca, Not set

Local Institution - 0067, Cluj-napoca, Not set

Local Institution - 0069, Ploiesti, Not set

Local Institution - 0040, Barcelona, Not set

Local Institution - 0041, Las Palmas De Gran Canaria, Not set

Local Institution - 0047, Madrid, Not set

Local Institution - 0042, Malaga, Not set

Local Institution - 0039, Sevilla, Not set

Local Institution - 0043, Valencia, Not set

Local Institution - 0127, Stockholm, Not set

Local Institution - 0125, Uppsala, Not set

Local Institution - 0076, Chur, Not set

Local Institution - 0077, Lausanne, Not set

Local Institution - 0078, Zuerich, Not set

Local Institution - 0157, Taipei, Not set

Local Institution - 0130, Kayseri, Not set

Local Institution - 0098, London, Greater London

Local Institution - 0097, Manchester, Greater Manchester

Local Institution - 0053, Leeds, Yorkshire

Conditions: Stage IV or Recurrent Non-Small Cell Lung Cancer

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NEOadjuvant Trial in Adenocarcinoma of the oEsophagus and oesophagoGastric Junction International Study (Neo-AEGIS)

NCT01726452

Completed

This is a multicentre phase III open-labelled, randomised controlled trial. Eligible patients will be randomised in a 1:1 fashion between neoadjuvant and adjuvant chemotherapy (Investigator's choice modified MAGIC (ECF/ECX or EOF/EOX) or FLOT regimen) and surgery or Arm B (CROSS protocol: chemotherapy with radiation therapy and surgery as per multimodal protocol). Primary Objective: To evaluate one, two and three year survival of patients treated with resection plus neoadjuvant and adjuvant ch... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

09/29/2022

Locations: Rigshospitalet, Blegdamsvej 9, Not set +28 locations

Rigshospitalet, Blegdamsvej 9, Not set

Centre Hospitalier Régional, Universitaire de Lille 2 Avenue Oscar Lambret, 59000, Lille, Not set

Cork University Hospital, Cork, Not set

Beaumont Hospital, Dublin, Not set

SLRON- St Luke's Radiation Oncology Network, Dublin, Not set

St. James's Hospital, Dublin, Not set

University Hospital Galway, Galway, Not set

Karolinska Institutet and Karolinska University Hospital, Stockholm, Not set

The Royal Bournemouth Hospital, The Royal Bournemouth And Christchurch Hospitals NHS Foundation, Bournemouth

Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Box 279(s4), Cambridge Biomedical Camp, Cambridge

Velindre Cancer Centre, Velindre NHS Trust, Velindre Road, Whitchurch, Cardiff

University Hospitals Coventry & Warwickshire, Clifford Bridge Road, Walsgrave, Coventry

Hull and East Yorkshire Hospitals NHS Trust, Castle Hill Hospital,, Cottingham, East Riding Of Yorkshire

Portsmouth Hospitals NHS Trust, Southwick Hill Road, Cosham, Hampshire

Mount Vernon Cancer Centre, E & N Hertfordshire NHS Trust, Rickmansworth Road, Northwood, Middlesex

Nottingham City Hospital, Nottingham University Hospitals NHS Trust, Hucknall Road, Nottingham

Oxford University Hospital NHS Trust Churchill Hospital, Headington, Oxfordshire

University Hospital Southampton NHS Foundation Trust, Southampton General Hospital, Division A Cancer Care, Mp307, T, Southampton

Royal Surrey County Hospital, Guildford, Surrey

Worcestershire Royal Hospital, Worcestershire Oncology Centre, Charles Hastings Way, Worcester

Belfast Health and Social Care Trust, Northern Ireland Cancer Centre, Belfast CityHospital, Belfast, Not set

The Clatterbridge Cancer Centre NHS Foundation Trust, Birkenhead, Wirral, Not set

University Hospitals Bristol NHS Foundation Trust, Bristol, Not set

University Hospital Plymouth NHS Trust, Derriford Hospital, Derriford Road, Crownhill, Plymouth, Not set

NHS Lothian, Edinburgh Cancer Centre,, Edinburgh, Not set

Beatson West of Scotland Cancer Centre, Glasgow, 1056 Great Western Road, Not set

Imperial College Healthcare NHS Trust St Mary's Hospital, London, Not set

The Newcastle upon Tyne Hospital NHS Foundation TrustFreeman Hospital, Freeman Road, High Heaton, Newcastle upon Tyne, Not set

Royal Preston Hospital, Sharoe Garoo Lane, Fulwood, Preston, Not set

Conditions: Adenocarcinoma of the Oesophagus, Adenocarcinoma of the Oesophago-gastric Junction, Oesophageal Tumours, Junctional Tumours, Oesophageal Cancer

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A Study of Pembrolizumab (MK-3475) in Combination With Etoposide/Platinum (Cisplatin or Carboplatin) for Participants With Extensive Stage Small Cell Lung Cancer (MK-3475-604/KEYNOTE-604)

NCT03066778

Completed

The purpose of this study is to assess the safety and efficacy of pembrolizumab plus standard of care (SOC) chemotherapy (etoposide/platinum \[EP\]) in participants with newly diagnosed extensive stage small cell lung cancer (ES-SCLC) who have not previously received systemic therapy for this malignancy. The primary study hypotheses are that pembrolizumab+EP prolongs Progression-free Survival (PFS) per Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 by blinded independent cent... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

09/02/2022

Locations: Baptist Health Medical Group Oncology, LLC ( Site 8000), Miami, Florida +147 locations

Baptist Health Medical Group Oncology, LLC ( Site 8000), Miami, Florida

Rush University Medical Center ( Site 1215), Chicago, Illinois

North Shore University Health System ( Site 1216), Evanston, Illinois

Community Hospital ( Site 1207), Munster, Indiana

Weinberg Cancer Institute at Franklin Square ( Site 1210), Baltimore, Maryland

Massachusetts General Hospital ( Site 1203), Boston, Massachusetts

Beth Israel Deaconess Medical Center ( Site 1206), Boston, Massachusetts

Dana-Farber Cancer Institute [Boston] ( Site 1201), Boston, Massachusetts

University of Michigan ( Site 1217), Ann Arbor, Michigan

Henry Ford Health System ( Site 1221), Detroit, Michigan

Minnesota Oncology Hematology, PA ( Site 8001), Minneapolis, Minnesota

Hattiesburg Clinic ( Site 1205), Hattiesburg, Mississippi

Mercy Hospital Saint Louis ( Site 1213), Saint Louis, Missouri

Comprehensive Cancer Centers of Nevada ( Site 8004), Henderson, Nevada

Memorial Sloan-Kettering Cancer Center At Basking Ridge ( Site 1226), Basking Ridge, New Jersey

Memorial Sloan Kettering Cancer Center- Monmouth ( Site 1225), Middletown, New Jersey

Montefiore Einstein Center for Cancer Care - Main site ( Site 1204), Bronx, New York

Montefiore Medical Center ( Site 1222), Bronx, New York

Memorial Sloan-Kettering Cancer Center at Commack ( Site 1227), Commack, New York

Memorial Sloan Kettering Cancer Center ( Site 1229), Harrison, New York

Memorial Sloan Kettering Cancer Center ( Site 1211), New York, New York

Memorial Sloan Kettering Cancer Center - Rockville Centre ( Site 1228), Rockville Centre, New York

Duke University Medical Center ( Site 1214), Durham, North Carolina

Bon Secours St. Francis Health Sytem ( Site 1212), Greenville, South Carolina

Tennessee Oncology, PLLC/The Sarah Cannon Research Institute ( Site 1230), Nashville, Tennessee

Texas Oncology ( Site 8002), Austin, Texas

Texas Oncology-Baylor Charles A. Sammons Cancer Center ( Site 8003), Dallas, Texas

Blacktown Hospital ( Site 0004), Blacktown, New South Wales

Southern Medical Day Care Centre ( Site 0001), Wollongong, New South Wales

St John of God ( Site 0006), Murdoch, Western Australia

Lyell McEwin Hospital ( Site 0002), Elizabeth Vale, Not set

St Vincents Hospital Melbourne ( Site 0005), Fitzroy, Not set

Cancer Care Manitoba ( Site 0159), Winnipeg, Manitoba

Nova Scotia Health Authority ( Site 0157), Halifax, Nova Scotia

William Osler Health System (Brampton Civic Hospital) ( Site 0161), Brampton, Ontario

Kingston Health Sciences Centre ( Site 0155), Kingston, Ontario

Sunnybrook Research Institute ( Site 0151), Toronto, Ontario

CISSS de la Monteregie-Centre ( Site 0152), Greenfield Park, Quebec

CISSS-CA Hotel Dieu de Levis ( Site 0154), Lévis, Quebec

CIUSSS Ouest de l'Ile - St-Mary's Hospital ( Site 0158), Montreal, Quebec

St. Jerome Medical Research Inc. ( Site 0160), St-Jerome, Quebec

Instituto Nacional del Cancer ( Site 0207), Santiago, Region Metropolitana

Health and Care Chile ( Site 0202), Santiago, Not set

Fundacion Arturo Lopez Perez FALP ( Site 0203), Santiago, Not set

Pontificia Universidad Catolica de Chile ( Site 0206), Santiago, Not set

Clinica Universidad Catolica del Maule ( Site 0208), Talca, Not set

CHRU de Lille - Hopital Albert Calmette ( Site 0353), Lille, Not set

C.H.R.U. De Limoges ( Site 0358), Limoges, Not set

CHU Nantes - Hopital Laennec ( Site 0363), Nantes, Not set

Centre Antoine Lacassagne ( Site 0362), Nice, Not set

Hopital Tenon ( Site 0360), Paris, Not set

Institut de Cancerologie Jean-Godinot ( Site 0351), Reims, Not set

CHU de Toulouse - Hopital Larrey ( Site 0354), Toulouse, Not set

Evangelische Lungenklinik Berlin ( Site 0403), Berlin, Not set

Medizinische Fakultaet Carl Gustav Carus der TU Dresden ( Site 0411), Dresden, Not set

Florence Nightingale Krankenhaus ( Site 0413), Duesseldorf, Not set

SRH Waldklinikum Gera GmbH ( Site 0405), Gera, Not set

Asklepios Klinikum Harburg ( Site 0412), Hamburg, Not set

Thoraxklinik Heidelberg gGmbH am Universitaetsklinikum Heidelberg ( Site 0401), Heidelberg, Not set

Philipps-Universitat Marburg ( Site 0414), Marburg, Not set

Universitaetsklinikum Tuebingen ( Site 0404), Tuebingen, Not set

Orszagos Onkologiai Intezet ( Site 0453), Budapest, Pest

Orszagos Koranyi TBC es Pulmonologiai Intezet ( Site 0452), Budapest, Not set

Orszagos Koranyi TBC es Pulmonologiai Intezet ( Site 0458), Budapest, Not set

Orszagos Koranyi TBC es Pulmonologiai Intezet ( Site 0459), Budapest, Not set

Veszprem Megyei Tudogyogyintezet ( Site 0454), Farkasgyepu, Not set

Petz Aladar Megyei Oktato Korhaz ( Site 0460), Gyor, Not set

Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz ( Site 0456), Szekesfehervar, Not set

Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointezet ( Site 0451), Szolnok, Not set

Zala Megyei Szent Rafael Korhaz ( Site 0457), Zalaegerszeg, Not set

St Vincents University Hospital ( Site 1456), Dublin, Not set

St James Hospital ( Site 1452), Dublin, Not set

Soroka Medical Center ( Site 0505), Beer Sheva, Not set

Ramban Medical Center - Dept. Hemato. & B. Marrow Transplant ( Site 0502), Haifa, Not set

Meir Medical Center ( Site 0503), Kfar Saba, Not set

Rabin Medical Center ( Site 0504), Petah Tikva, Not set

Chaim Sheba Medical Center. ( Site 0501), Ramat-Gan, Not set

National Hospital Organization Nagoya Medical Center ( Site 0615), Nagoya, Aichi

National Cancer Center Hospital East ( Site 0613), Kashiwa, Chiba

National Hospital Organization Shikoku Cancer Center ( Site 0614), Matsuyama, Ehime

Kurume University Hospital ( Site 0609), Kurume, Fukuoka

Hyogo Cancer Center ( Site 0611), Akashi, Hyogo

Kanagawa Cancer Center ( Site 0618), Yokohama, Kanagawa

Sendai Kousei Hospital ( Site 0602), Sendai, Miyagi

National Hospital Organization Kinki-chuo Chest Medical Center ( Site 0608), Sakai, Osaka

Shizuoka Cancer Center Hospital and Research Institute ( Site 0607), Sunto-gun, Shizuoka

National Hospital Organization Yamaguchi Ube Medical Center ( Site 0601), Ube, Yamaguchi

National Hospital Organization Kyushu Medical Center ( Site 0617), Fukuoka, Not set

Hiroshima University Hospital ( Site 0604), Hiroshima, Not set

Niigata Cancer Center Hospital ( Site 0610), Niigata, Not set

Osaka International Cancer Institute ( Site 0616), Osaka, Not set

The Cancer Institute Hospital of JFCR ( Site 0606), Tokyo, Not set

Wakayama Medical University Hospital ( Site 0612), Wakayama, Not set

Inje University Haeundae Paik Hospital ( Site 0905), Busan, Not set

National Cancer Center ( Site 0904), Goyang-si, Not set

Severance Hospital Yonsei University Health System ( Site 0903), Seoul, Not set

Asan Medical Center ( Site 0901), Seoul, Not set

Samsung Medical Center ( Site 0902), Seoul, Not set

Canterbury Regional Cancer & Blood Services ( Site 0701), Christchurch, Not set

Mazowiecki Szpital Onkologiczny ( Site 0757), Wieliszew, Mazowieckie

Przychodnia Lekarska Komed ( Site 0769), Konin, Not set

Krakowski Szpital Specjalistyczny im. Jana Pawla II ( Site 0768), Krakow, Not set

Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli ( Site 0767), Lublin, Not set

SKPP UM im. Karola Marcinkowkiego w Poznaniu ( Site 0766), Poznan, Not set

Wielkopolskie Centrum Pulmonologii i Torakochirurgii ( Site 0762), Poznan, Not set

Wojewodzki Szpital Zespolony im. L. Rydygiera w Toruniu ( Site 0756), Torun, Not set

Centrum Onkologii-Instytut im. Marii Sklodowskiej-Curie ( Site 0751), Warszawa, Not set

Dolnoslaskie Centrum Onkologii we Wroclawiu ( Site 0771), Wroclaw, Not set

Belgorod Regional Oncology Dispensary ( Site 0804), Belgorod, Not set

N.N. Blokhin NMRCO ( Site 0801), Moscow, Not set

SBI of Stavropol region Pyatigorskiy Oncologic dispensary ( Site 0811), Pyatigorsk, Not set

SBHI Leningrad Regional Clinical Hospital ( Site 0803), Saint Petersburg, Not set

Municipal Clinical Oncology Center ( Site 0802), Saint Petersburg, Not set

Hospital Universitario Insular de Gran Canaria ( Site 0952), Las Palmas de Gran Canaria, Gran Canaria

Complejo Hospitalario Universitario de A Coruna ( Site 0953), A Coruna, Not set

Hospital del Mar ( Site 0956), Barcelona, Not set

Hospital Universitari Vall d Hebron ( Site 0951), Barcelona, Not set

Hospital Ciudad de Jaen ( Site 0957), Jaen, Not set

Hospital General Universitario Gregorio Maranon ( Site 0958), Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz ( Site 0954), Madrid, Not set

Hospital Clinico Universitario de Valencia ( Site 0955), Valencia, Not set

Kantonsspital Graubuenden ( Site 1403), Chur, Not set

CHUV Centre Hospitalier Universitaire Vaudois ( Site 1405), Lausanne, Not set

Universitaetsspital Zuerich ( Site 1404), Zuerich, Not set

Kaohsiung Chang Gung Memorial Hospital of the C.G.M.F. ( Site 1005), Kaohsiung, Not set

China Medical University Hospital. ( Site 1003), Taichung, Not set

Taichung Veterans General Hospital ( Site 1007), Taichung, Not set

National Cheng Kung University Hospital ( Site 1004), Tainan, Not set

Chi Mei Medical Center Liuying ( Site 1006), Tainan, Not set

National Taiwan University Hospital ( Site 1001), Taipei, Not set

Taipei Veterans General Hospital ( Site 1002), Taipei, Not set

Ege Universitesi Tıp Fakultesi ( Site 1052), Izmir, Bornova

Baskent University Adana Dr. Turgut Noyan EAH ( Site 1057), Adana, Not set

Ankara UTF ( Site 1055), Ankara, Not set

Hacettepe Universitesi Tip Fakultesi Hastanesi ( Site 1060), Ankara, Not set

Dr. Abdurrahman Yurtaslan Ankara Onkoloji EAH ( Site 1053), Ankara, Not set

Trakya Uni. Tip Fakultesi ( Site 1063), Edirne, Not set

Istanbul Universitesi Cerrahpasa Tip Fakultesi ( Site 1058), Istanbul, Not set

Medipol Hastanesi ( Site 1066), Istanbul, Not set

Medeniyet Uni. Goztepe Egitim ve Arast. Hast. ( Site 1064), Istanbul, Not set

Medical Park Izmir Hospital ( Site 1051), Izmir, Not set

Kocaeli Universitesi Tip Fakultesi ( Site 1061), Kocaeli, Not set

Inonu Universitesi Tip Fakultesi ( Site 1059), Malatya, Not set

Birmingham Heartlands Hospital ( Site 1162), Birmingham, Not set

St James s University Hospital ( Site 1161), Leeds, Not set

North Middlesex Hospital ( Site 1151), London, Not set

Maidstone Hospital ( Site 1155), Maidstone, Not set

Mount Vernon Cancer Centre ( Site 1156), Northwood, Not set

Conditions: Small Cell Lung Cancer (SCLC)

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A Study Of PF-05212384 In Combination With Other Anti-Tumor Agents and in Combination With Cisplatin in Patients With Triple Negative Breast Cancer in an Expansion Arm (TNBC)

NCT01920061

Completed

This study will evaluate PF-05212384 (gedatolisib) PI3K/mTOR inhibitor)) in combination with either docetaxel, cisplatin or dacomitinib in select advanced solid tumors. The study will assess the safety, pharmacokinetics and pharmacodynamics of these combinations in patients with advanced cancer in order to determine the maximum tolerated dose in each combination. The cisplatin combination expansion portion will evaluate the anti tumor activity of PF 05212384 plus cisplatin in patients with TNBC... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/20/2022

Locations: University of Alabama at Birmingham, Birmingham, Alabama +28 locations

University of Alabama at Birmingham, Birmingham, Alabama

Ronald Reagan UCLA Medical Center, Los Angeles, California

UCLA Hematology Oncology, Los Angeles, California

Westwood Bowyer Clinic, Los Angeles, California

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California

Santa Monica UCLA Medical Center & Orthopaedic Hospital, Santa Monica, California

UCLA Hematology Oncology, Santa Monica, California

University of Colorado Denver CTO (CTRC), Aurora, Colorado

University of Colorado Hospital, Aurora, Colorado

Brigham and Women's Hospital, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Harper Professional Building, Detroit, Michigan

Karmanos Cancer Institute, Detroit, Michigan

Fox Chase Cancer Center, Philadelphia, Pennsylvania

Medical University of South Carolina/ University Hospital, Charleston, South Carolina

Medical University of South Carolina, Charleston, South Carolina

MUSC SCTR Research, Charleston, South Carolina

MUSC Health East Cooper, Mount Pleasant, South Carolina

MUSC Specialty Care-North, North Charleston, South Carolina

British Columbia Cancer Agency - Vancouver Centre, Vancouver, British Columbia

Princess Margaret Cancer Center, Toronto, Ontario

Istituto Europeo di Oncologia - Divisione Sviluppo di Nuovi Farmaci per Terapie Innovative, Milano, MI

Istituto Regina Elena Struttura Complessa Oncologia Medica A, Roma, RM

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

University College London Hospital, NIHR UCLH Clinical Research Facility, London, Not set

Oxford Cancer Centre, Oxford, Not set

Conditions: Neoplasm

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Efficacy and Safety Study of Leukocyte Interleukin,Injection (LI) to Treat Cancer of the Oral Cavity

NCT01265849

Completed

The purpose of this study was to determine whether LI administered in combination with cyclophosphamide, indomethacin and zinc in a multivitamin (CIZ) combination prior to standard of care therapy (surgery followed by radiotherapy or concurrent radiochemotherapy) is safe and will increase the overall survival of subjects with previously untreated locally advanced primary squamous cell carcinoma of the oral cavity or soft palate at a median of 3 to 5 years

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/17/2022

Locations: Simmons Cancer Institute at Southern Illinois University, Springfield, Illinois +101 locations

Simmons Cancer Institute at Southern Illinois University, Springfield, Illinois

Henry Ford Health System Henry Ford Hospital, Detroit, Michigan

University of Cincinnati Medical Center, Cincinnati, Ohio

Medical College Of South Carolina MSC550, Charleston, South Carolina

VA Puget Sound Healthcare System & University of WA, Seattle, Washington

HNO-Klinik der medizinischen Universitat Graz, Graz, Not set

N.N. Alexandrov Research Istitute of Oncology and Medical Radiology, Lesnoy 2, Minsk

Vitebsk Regional Oncology Dispensary, Vitebsk, Not set

University Clinical Centre Tuzla, Trnovac, Tuzla

Clinical Center Banja Luka, Banja Luka, Not set

University Clinical Hospital Mostar, Mostar, Not set

Clinical Centre University of Sarejevo Clinic for ENT, Sarajevo, Not set

St. Josephs Healthcare Department of Surgery, Hamilton, Ontario

Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec

CHU de Quebec - L'Hotel Dieu de Quebec, Quebec, Not set

CHC Osijek, Osijek, Not set

General Hospital Dr. Josip Bencevic, Slavonski Brod, Not set

CH Dubrava, Zagreb, Not set

Clinical Hospital Center Zagreb Kispaticeva 12, Zagreb, Not set

KBC Sestre Milosrdnice, Zagreb, Not set

KBC Zagreb, Zagreb, Not set

ICL 6 avenue Bourgogne CS30519, Vandoeuvre les Nancy, Not set

University of Debrecen Medical and Health Scioence Centre, Debrecen, Hajdu Bihar

National institute of Oncology, Budapest, Rath Gyorgy

Semmelweis University, Budapest, Not set

University of Pecs Institute of Oncotherapy, Pecs, Not set

University of Szeged Dept of Oral and Maxillofacial Surgery, Szeged, Not set

Markusovsky Teaching Hospital, Szombathely, Not set

Bibi General Hospital and Cancer Centre, Malkapet, Andhra Pradesh

Amrita Institute of Medical Sciences, Kochi, Kerala

Sujan Regional Cancer Hospital & Amravati Cancer Foundation, Amravati, Maharashtra

Government Medical College and Hospital, Aurangabad, Maharashtra

Tata Memorial Hospital, Mumbai, Maharashtra

Curie Manavata Cancer Center, Mumbai, Naka Nashik

Searoc Cancer Center, Jaipur, Rajashlan

V.N. Cancer Center G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, Tamil Nadu

Meenakshi Mission Hospital and Research Centre, Madurai, Tamil Nadu

Regional Cancer Center, Kerola, Thiruvananthapuram

Galaxy Cancer Center, Ghaziabad, Uttar Pradesh

Rambam Health Care Campus, Sha'ar Ha'Aliya, Saint Haifa

Rabin Medical Center, Petaẖ Tiqwa, Tikva

National Tumor Institute of Italy, Naples, Not set

Ospedale S.G. Moscati Santissima Annunziata, Taranto, Not set

Dept of Head and Neck Surgery School of Medical Sciences Univ. Sains, Kuantan, Penang

University Kabangsan Medical Center, Kuala Lumpur, Not set

Wojewodzki Szpital Specjalistyczny im Kopernika, Lodz, Ul Paderewskiego 4

Swietokrzyskie Centrum Onkologii, Kielce, Ul. Artwinskiego 3

Centrum Onkologii im. Prof. Lukaszcyka, Warsaw, Ul. Roentgena 5

Centrum Onkologi-Instytut im. Marie Sklodowskiej-Curie, Warszawa, Ul. Roentgena 5

ul. M. Sklodowskiej-Curie 24A, Bialystok, Not set

Szpital Specialistyczny im. Ludwika Rydgiera, Krakow, Not set

Samodzielny Publiczny Szpital Kliniczny Klinika Otolarryngologii I Onkologii Laryngologicznej, Lublin, Not set

Weilkopolskie Centrum Onkologii Klinika Chirurgii Glowy Szye Onkologii Laryngologiczne, Poznan, Not set

Uniwersitecki Szpital Kliniczny Klinika Otolaryngologii Chirugii Glowy i Szxyi, Wroclaw, Not set

Regional Institute of Oncology IASI, Iasi, Not set

Spital Clinic Judetean Mures, Targu Mures, Not set

Sverdlovsk Regional Cancer Center, Sverdlov, Ekaterinberg

Leningrad Regional Oncology Center, St. Petersburg, Leningradskaya

Kursk Regional Clinical Oncology Dispensary, Kursk, Not set

Blokhin Cancer Research Center, Moscow, Not set

N.N. Blokhin Russian Cancer Research Center, Moscow, Not set

Budget Institution of Healthcare of Omsk Region Clincal Oncology Dispensary, Omsk, Not set

Ryazan Clinical oncology Dispensary, Ryazan, Not set

Serbia Clinic for ENT and Maxillofacial Surgery, Belgrade, Pasterova 14

Clincal Center Serbia Clinic for Oral and Maxillofacial Surgery, Belgrade, Not set

Faculty of Dental Medicine Clinic for Maxillofacial Surgery, Belgrade, Not set

Military Medical Academy Clinic for Maxillofacial Surgery, Belgrade, Not set

Clinical Center Nis center for Oncology, Nis, Not set

Clinic for Stomatology department for maxillofacial Surgery, Nis, Not set

Clinical center Vojvodina Clinic for ORL, Novi Sad, Not set

Clinical Centre Vojvodina Clinic for Maxillofacial Surgery, Novi Sad, Not set

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Hospital Universitario de Princesa, Madrid, Not set

Hospital Universitario Ramon y Cajal, Madrid, Not set

Hospital Madrid North Universitaro de Sanchinnaro, Madrid, Not set

Complejo Hospitalario Univ. de Santiago, Santiago de Compostela, Not set

Consorsio Hospital General Universitario de valencia, Valencia, Not set

National Cancer Institute Dept of Clinical Oncology & Radiotherapy, Colombo, Not set

Oncology Unit Teaching Hospital Karapitya, Galle, Not set

Kaohsiung Branch Chang Gung Memorial Hospital, Niaosong, Kaohsiung

National Cheng Kung University Hospital, Taipei, Tainan

National Taiwan Research Hospital, Chengshan, Taipei

Linkou Branch Chang Gung Memorial Hospital, Guishan, Taoyuan

Changua Christian Hospital, Chang-hua, Not set

Buddhist Tzu Chi General Hospital, Hualien Branch, Hualien City, Not set

China Medical University Hospital, Taichung, Not set

Taichung Veterans General Hospital, Taichung, Not set

Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Not set

Khon Kaen University Dept of Otolaryngology, Nai- Muang, Not set

Haceteppe University Dept of Otolaryngology - Head and Neck Surgery, Ankara, Not set

Acibadem University Maslak Hospital ENT Department, Istanbul, Not set

Cherkasky Regional Oncological Dyspensary Dept. Head and Neck tumour, Cherkasy, Not set

Clinical Diagnostic Laboratory of Dnepropetrovsk Municipal Institution City Multidisciplinary Clinical Hospital No. 4, Dnepropetrovsk, Not set

Donetsk Regional Antitumor Center, Donetsk, Not set

Grigoriev Institute for Medical Radiology of National Academy of Medical Science of Ukraine Dept. of Remote, Combined Radiation and Complex Therapy, Kharkiv, Not set

Kharkiv Regional Clinical Oncology Center Dept. Of Head and Neck Tumour, Kharkiv, Not set

Kiev City Clinical Oncology Center of the Main Health Care Dept of Kiev Day Hospital Radiotherapy Dept., Kiev, Not set

Kiev City Clinical Oncology Center of the Main Health Care Dept. of the Kiev Day Hospital, Kiev, Not set

Lviv State OncologyRegional treatment and Diagnostic Center, Lviv, Not set

Sumy Regional Clinical Oncology Dyspensary, Sumy, Not set

Zaporiz'ka Regional Clinical Oncology Dispensary, Zaporiz'ka Oblast', Not set

Aintree University Hospital, Liverpool, Not set

Conditions: Squamous Cell Carcinoma of the Oral Cavity, Squamous Cell Carcinoma of the Soft Palate

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Phase 1b Multi-indication Study of Anetumab Ravtansine in Mesothelin Expressing Advanced Solid Tumors

NCT03102320

Completed

The key purpose of the main part of the study is to assess efficacy and safety of anetumab ravtansine as monotherapy or combination therapy for mesothelin expressing advanced solid tumors. The main purpose of the safety lead-in (dose-finding) part of the study is to determine the safety and tolerability of anetumab ravtansine in combination with cisplatin and in combination with gemcitabine, and to determine the MTD of anetumab ravtansine in combination with cisplatin for mesothelin expressing... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/28/2022

Locations: Mayo Clinic Hospital, Phoenix, Arizona +71 locations

Mayo Clinic Hospital, Phoenix, Arizona

University of Southern California, Los Angeles, California

Stanford Health Care, Stanford, California

MedStar Georgetown University Hospital, Washington, District of Columbia

Indiana University School of Medicine, Indianapolis, Indiana

Ochsner Medical Center - New Orleans, New Orleans, Louisiana

National Cancer Institute - Maryland, Bethesda, Maryland

Barbara Ann Karmanos Cancer Institute, Farmington Hills, Michigan

Mayo Clinic - Rochester, Rochester, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Vanderbilt University Medical Center, Nashville, Tennessee

Texas Oncology, PA, Dallas, Texas

University of Texas MD Anderson Cancer Center, Houston, Texas

Blacktown Cancer & Haematology Centre, Blacktown, New South Wales

Mid North Coast Cancer Institute, Coffs Harbour, New South Wales

Kinghorn Cancer Centre, Darlinghurst, New South Wales

Northern Cancer Institute, St Leonards, New South Wales

Flinders Medical Centre, Adelaide, South Australia

Epworth HealthCare, Richmond, Victoria

Sir Charles Gairdner Hospital, Nedlands, Western Australia

St John of God Healthcare, Subiaco, Western Australia

Hôpital Erasme/Erasmus Ziekenhuis, Bruxelles - Brussel, Not set

UZ Antwerpen, Edegem, Not set

UZ Leuven Gasthuisberg, Leuven, Not set

CHU de Liège, Liege, Not set

Cross Cancer Institute, Edmonton, Alberta

Princess Margaret Cancer Centre - UHN, Toronto, Ontario

Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec

McGill University Health Center, Montreal, Quebec

Hopital Jean Minjoz, Besancon, Not set

Hôpital Henri Mondor, Creteil, Not set

Centre Oscar Lambret - Lille, Lille Cedex, Not set

Centre Léon Bérard, Lyon Cedex, Not set

C.H.U. Timone, Marseille, Not set

Centre René Gauducheau, Nantes, Not set

Centre Antoine Lacassagne, Nice Cedex 2, Not set

Centre Hospitalier Lyon Sud, Pierre Benite, Not set

Hôpital de la Milétrie, POITIERS cedex, Not set

Hôpital Pontchaillou, Rennes Cedex, Not set

Centre Eugène Marquis - Rennes Cedex, Rennes Cedex, Not set

Institut Gustave Roussy, Villejuif Cedex, Not set

A.O.U. di Bologna Policlinico S.Orsola Malpighi, Bologna, Emilia-Romagna

A.O.U. di Modena - Policlinico, Modena, Emilia-Romagna

Istituto Clinico Humanitas - Humanitas Mirasole S.p.A., Milano, Lombardia

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Lombardia

ASST Grande Ospedale Metropolitano Niguarda, Milano, Lombardia

A.O.U.I. Verona, Verona, Veneto

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Nederlands Kanker Instituut, Amsterdam, Not set

Maastricht UMC, Maastricht, Not set

National University Hospital, Singapore, Not set

National Cancer Center Singapore, Singapore, Not set

Hospital Universitario Quirón de Madrid, Pozuelo de Alarcón, Madrid

Hospital del Mar, Barcelona, Not set

Ciutat Sanitària i Universitaria de la Vall d'Hebron, Barcelona, Not set

Hospital Clínic i Provincial de Barcelona, Barcelona, Not set

Hospital General Universitario Gregorio Marañón | Oncología, Madrid, Not set

Hospital Ramón y Cajal | Oncología, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Centro Integral Oncológico Clara Campal, Madrid, Not set

Hospital Virgen de la Victoria, Málaga, Not set

Kantonsspital Graubünden, Chur, Graubünden

Ospedale Regionale Bellinzona, Bellinzona, Ticino

Leicester Royal Infirmary, Leicester, Leicestershire

Belfast City Hospital, Belfast, North Ireland

Royal Marsden NHS Trust (Surrey), Sutton, Surrey

Guy's Hospital, London, Not set

Royal Marsden Hospital (London), London, Not set

Christie Hospital, Manchester, Not set

Conditions: Neoplasms

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International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma

NCT02066220

Active Not Recruiting

The study PNET 5 MB has been designed for children with medulloblastoma of standard risk (according to the risk-group definitions which have been used so far; e.g. in PNET 4). With the advent of biological parameters for stratification into clinical medulloblastoma trials, the ß-catenin status will be the only criterion according to which study patients will be assigned to either treatment arm PNET 5 MB - LR or to PNET 5 MB - SR, respectively. The initial diagnostic assessments (imaging, staging... Read More

Gender:

ALL

Ages:

Between 3 years and 21 years

Trial Updated:

04/11/2022

Locations: Medical University of Graz, Graz, Not set +76 locations

Medical University of Graz, Graz, Not set

University Hospital Gasthuisberg, Leuven, Not set

University Hospital Brno, Brno, Not set

Rigshospitalet, Copenhagen, Not set

CHU de Grenoble, Grenoble, Not set

Institute Curie, Paris Cedex 05, Not set

CHU-TOURS - Hôpital Clocheville, Tours, Not set

Hôpital NANCY-BRABOIS, Vandoeuvre Les Nancy, Not set

University Hospital Aachen, Aachen, Not set

Klinikum Augsburg, Augsburg, Not set

Helios Klinikum Berlin-Buch, Berlin, Not set

Charite Campus, University of Berlin, Berlin, Not set

Evangelisches Krankenhaus Bielefeld, Bielefeld, Not set

University Hospital Bonn, Bonn, Not set

Klinikum Braunschweig, Braunschweig, Not set

Klinikum Bremen-Mitte, Bremen, Not set

Klinikum Chemnitz, Chemnitz, Not set

University Hospital Cologne, Cologne, Not set

Carl-Thiem-Klinikum Cottbus, Cottbus, Not set

Vestische Kinder- und Jugendklinik, University Witten/Herdecke, Datteln, Not set

Klinikum Dortmund, Dortmund, Not set

University Hospital Dresden, Dresden, Not set

Klinikum Duisburg, Duisburg, Not set

University Hospital Düsseldorf, Düsseldorf, Not set

HELIOS Klinikum-Erfurt, Erfurt, Not set

University Hospital Erlangen, Erlangen, Not set

University Hospital Essen, Essen, Not set

University Hospital Frankfurt/Main, Frankfurt, Not set

University Hospital Freiburg, Freiburg, Not set

University Hospital Gießen and Marburg, Gießen, Not set

University Hospital Greifswald, Greifswald, Not set

University Hospital Göttingen, Göttingen, Not set

University Hospital Halle/Saale, Halle, Not set

University Medical Center Hamburg-Eppendorf, Hamburg, Not set

Medizinische Hochschule Hannover, Hannover, Not set

Angelika-Lautenschläger-Klinik, Heidelberg, Not set

Gemeinschaftskrankenhaus Herdecke, Herdecke, Not set

University Hospital Homburg/Saar, Homburg, Not set

University Hospital Jena, Jena, Not set

Städtisches Klinikum Karlsruhe, Karlsruhe, Not set

Klinikum Kassel, Kassel, Not set

UK-SH Campus Kiel, Kiel, Not set

Gemeinschaftsklinikum Koblenz-Mayen, Koblenz, Not set

HELIOS Klinikum Krefeld, Krefeld, Not set

Kliniken der Stadt Köln, Köln, Not set

University Hospital Leipzig, Leipzig, Not set

University Hospital Lübeck, Lübeck, Not set

University Hospital Magdeburg, Magdeburg, Not set

University Hospital Mainz, Mainz, Not set

University Hospital Mannheim, Mannheim, Not set

Johannes Wesling Klinikum Minden, Minden, Not set

University Hospital München, Dr. von Haunersches Kinderspital, München, Not set

Klinikum Schwabing, Pediatric Hospital of Technical University, München, Not set

University Hospital Münster, Münster, Not set

Cnopf'sche Kinderklinik, Nürnberg, Not set

Klinikum Oldenburg, Oldenburg, Not set

University Hospital Regensburg, Regensburg, Not set

University Hospital Rostock, Rostock, Not set

Asklepios Klinik Sankt Augustin, Sankt Augustin, Not set

HELIOS-Kliniken Schwerin, Schwerin, Not set

Klinikum Stuttgart, Stuttgart, Not set

Mutterhaus der Borromäerinnen, Trier, Not set

University Hospital Tübingen, Tübingen, Not set

University Hospital Ulm, Ulm, Not set

Dr. Horst Schmidt Kliniken, Wiesbaden, Not set

Klinikum der Stadt Wolfsburg, Wolfsburg, Not set

University Hospital Würzburg, Würzburg, Not set

Our Lady's Children's Hospital, Dublin, Not set

Fondazione IRCCS Istituto Nazionale Tumori, Milano, Not set

Prinses Máxima Center for Pediatric Oncology, Bilthoven, Not set

Rigshospitalet, Oslo, Not set

The Children's Memorial Health Institute, Warsaw, Not set

University Hospital S.Joao, Porto, Not set

Oncology Hospital Cruces Bilbao, Baracaldo, Not set

Barncancercentrum Drottning Silvias Barnochungdomssjukhus, Göteburg, Not set

University Children's Hospital, Zürich, Not set

Great Ormond Street Hospital, London, Not set

Conditions: Brain Tumors

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An Investigational Immuno-therapy Study of Nivolumab Given After Surgery in Non-Small Cell Lung Cancer (NSCLC) Participants With Minimal Residual Disease

NCT03770299

Withdrawn

The purpose of this study is to determine if nivolumab added to the standard of care therapy (SOC) given after surgery is more effective than SOC alone in prolonging disease free survival in NSCLC participants with minimal residual disease detected after surgery.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/09/2022

Locations: Local Institution, Jacksonville, Florida +12 locations

Conditions: Non-Small Cell Lung Cancer, Non-Small-Cell Lung Carcinoma, Circulating Tumor DNA

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Eribulin Mesylate Administered in Combination With Gemcitabine Plus Cisplatin Versus Gemcitabine Plus Cisplatin Alone as First-Line Therapy for Locally Advanced or Metastatic Bladder Cancer

NCT01126749

Terminated

The purpose of this study is to determine whether Patients with Locally Advanced or Metastatic Bladder Cancer who receive Eribulin Mesylate Administered in Combination with Gemcitabine Plus Cisplatin Versus Gemcitabine Plus Cisplatin Alone as First-Line Therapy is safety and tolerable when administered to patients with locally advanced or metastatic bladder cancer and to gain preliminary data on whether patients may benefit from this combination.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

02/03/2022

Locations: Not set, Birmingham, Alabama +41 locations

Not set, Birmingham, Alabama

Not set, Tucson, Arizona

Not set, Fort Myers, Florida

Not set, Saint Petersburg, Florida

Not set, Ann Arbor, Michigan

Not set, Las Vegas, Nevada

Not set, East Orange, New Jersey

Not set, Rochester, New York

Not set, Chattanooga, Tennessee

Not set, Fort Worth, Texas

Not set, Houston, Texas

Not set, Webster, Texas

Not set, Huntington, Virginia

Not set, Northfork, West Virginia

Not set, Aachen Northwest, Not set

Not set, Berlin, Not set

Not set, Essen, Northwest, Not set

Not set, Goch, Northwest, Not set

Not set, Hamburg, HH, Not set

Not set, Tuebingen, BW, Not set

Not set, Wiesbaden, HE, Not set

Not set, Maastricht, Not set

Not set, Nieuwegein, Not set

Not set, Nijmegen, Not set

Not set, Barcelona, Not set

Not set, Elche- Alicante, Not set

Not set, Madrid, Not set

Not set, Sabadell, Not set

Not set, Dnipropetrovsk, Not set

Not set, Donetsk, Not set

Not set, Kharkiv, Not set

Not set, Kyiv, Not set

Not set, Lviv, Not set

Not set, Leicester, Not set

Not set, Liverpool, Not set

Not set, London, Not set

Not set, Manchester, Not set

Not set, Southampton, Not set

Conditions: Bladder Cancer

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First-line Treatment of Patients With Stage IV Nonsquamous Non-Small Cell Lung Cancer With Necitumumab (IMC-11F8) and Pemetrexed-Cisplatin

NCT00982111

Completed

The research study is testing the investigational drug necitumumab in the treatment of advanced non-small cell lung cancer. The aim of this study is to determine if necitumumab, given together with a standard chemotherapy combination consisting of cisplatin and pemetrexed will be more effective in improving participant disease than the standard chemotherapy combination alone.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

12/12/2021

Locations: ImClone Investigational Site, Nyack, New York +100 locations

ImClone Investigational Site, Nyack, New York

ImClone Investigational Site, Kogarah, New South Wales

ImClone Investigational Site, Hobart, Tasmania

ImClone Investigational Site, East Bentleigh, Victoria

ImClone Investigational Site, Rankweil, Not set

ImClone Investigational Site, Wien, Not set

ImClone Investigational Site, Duffel, Not set

ImClone Investigational Site, Liège, Not set

ImClone Investigational Site, Namur, Not set

ImClone Investigational Site, Barretos - SP, Not set

ImClone Investigational Site, Brasilia, Distrito Federal, Not set

ImClone Investigational Site, Goiania - GO, Not set

ImClone Investigational Site, Ijui, Not set

ImClone Investigational Site, Itajai, Not set

ImClone Investigational Site, Lajeado, Not set

ImClone Investigational Site, Porto Alegre/RS, Not set

ImClone Investigational Site, Ribeirão Preto - SP, Not set

ImClone Investigational Site, Salvador, Not set

ImClone Investigational Site, Santo Andre - SP, Not set

ImClone Investigational Site, São Paulo - SP, Not set

ImClone Investigational Site, Montreal, Quebec

ImClone Investigational Site, Pula, Not set

ImClone Investigational Site, Caen, Not set

ImClone Investigational Site, Paris, Not set

ImClone Investigational Site, Berlin, Not set

ImClone Investigational Site, Essen, Not set

ImClone Investigational Site, Frankfurt, Not set

ImClone Investigational Site, Gauting, Not set

ImClone Investigational Site, Großhansdorf, Not set

ImClone Investigational Site, Halle, Not set

ImClone Investigational Site, Hamburg, Not set

ImClone Investigational Site, Heidelberg, Not set

ImClone Investigational Site, Hemer, Not set

ImClone Investigational Site, Hofheim, Not set

ImClone Investigational Site, Karlsruhe, Not set

ImClone Investigational Site, Lostau, Not set

ImClone Investigational Site, Löwenstein, Not set

ImClone Investigational Site, Mainz, Not set

ImClone Investigational Site, München, Not set

ImClone Investigational Site, Münster, Not set

ImClone Investigational Site, Regensburg, Not set

ImClone Investigational Site, Ulm, Not set

ImClone Investigational Site, Athens, Not set

ImClone Investigational Site, Heraklion, Crete, Not set

ImClone Investigational Site, Patras, Not set

ImClone Investigational Site, Budapest, Not set

ImClone Investigational Site, Deszk, Not set

ImClone Investigational Site, Mosonmagyaróvár, Not set

ImClone Investigational Site, Szombathely, Not set

ImClone Investigational Site, Székesfehérvár, Not set

ImClone Investigational Site, Törökbálint, Not set

ImClone Investigational Site, Lido di Camaiore, Lucca

ImClone Investigational Site, Aviano, Pordenone

ImClone Investigational Site, Frosinone, Not set

ImClone Investigational Site, Genova, Not set

ImClone Investigational Site, Milano, Not set

ImClone Investigational Site, Parma, Not set

ImClone Investigational Site, Perugia, Not set

ImClone Investigational Site, Olsztyn, Not set

ImClone Investigational Site, Otwock, Not set

ImClone Investigational Site, Poznan, Not set

ImClone Investigational Site, Radom, Not set

ImClone Investigational Site, Szczecin, Not set

ImClone Investigational Site, Wroclaw, Not set

ImClone Investigational Site, Coimbra, Not set

ImClone Investigational Site, Lisboa, Not set

ImClone Investigational Site, Brasov, Not set

ImClone Investigational Site, Bucharest, Not set

ImClone Investigational Site, Cluj-Napoca, Not set

ImClone Investigational Site, Craiova, Dolj, Not set

ImClone Investigational Site, Iasi, Not set

ImClone Investigational Site, Sibiu, Not set

ImClone Investigational Site, Ivanovo, Not set

ImClone Investigational Site, Kirov, Not set

ImClone Investigational Site, Omsk, Not set

ImClone Investigational Site, St. Petersburg, Not set

ImClone Investigational Site, Ufa, Not set

ImClone Investigational Site, Yaroslavi, Not set

ImClone Investigational Site, Bratislava, Not set

ImClone Investigational Site, Nitra, Not set

ImClone Investigational Site, Bloemfontein, Free State

ImClone Investigational Site, Pretoria, Gauteng

Imclone Investigational Site, Sevilla, Andalucia

ImClone Investigational Site, Barcelona, Cataluña

ImClone Investigational Site, Terrassa, Cataluña

ImClone Investigational Site, Madrid, Communidad De Madrid

ImClone Investigational Site, Majadahonda, Communidad De Madrid

ImClone Investigational Site, L'Hospitalet de Llobregat, Not set

ImClone Investigational Site, Aberdeen, Not set

ImClone Investigational Site, Bournemouth, Not set

ImClone Investigational Site, Edinburgh, Not set

ImClone Investigational Site, Guildford, Not set

ImClone Investigational Site, Leeds, Not set

ImClone Investigational Site, Preston, Not set

Conditions: Non Small Cell Lung Cancer

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Study to Evaluate Tolerability of Iberdomide (CC-220) in Combination With Polatuzumab Vedotin Plus Rituximab or Tafasitamab or Rituximab Plus Chemotherapy in B-cell Lymphoma

NCT04882163

Withdrawn

This is a Phase 1b/2 randomized study of Iberdomide (CC-220) added to 3 different combination regimens (polatuzumab vedotin plus rituximab (Cohort A), tafasitamab (Cohort B), rituximab plus gemcitabine and platinum-based chemotherapy (Cohort C)) for participants with relapsed or refractory aggressive B-cell lymphoma (R/R a-BCL). All 3 cohorts will be open for enrollment at study start. Part 1 (dose escalation) will be followed by Part 2 (dose expansion), in which participants will be randomized... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

09/28/2021

Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts +26 locations

Beth Israel Deaconess Medical Center, Boston, Massachusetts

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Avera Cancer Institute, Sioux Falls, South Dakota

Medizinische Universität Graz, Graz, Not set

Universitätsklinikum St. Pölten, Sankt Pölten, Not set

Cliniques Universitaires Saint-Luc, Brussels, Not set

Hôpital de Jolimont, La Louvière, Not set

H.-Hartziekenhuis Roeselare-Menen vzw, Roeselare, Not set

EDOG - Institut Bergonie - PPDS, Bordeaux, Not set

Hôpital François Mitterand, Dijon, Not set

Centre Hospitalier Lyon Sud, Lyon, Not set

EDOG - Institut Claudius Regaud - PPDS, Toulouse, Not set

Gustave Roussy, Villejuif CEDEX, Not set

Samsung Medical Center, Seoul, Not set

Asan Medical Center, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Hospital Universitario Germans Trias i Pujol, Badalona, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Complejo Asistencial Universitario de Salamanca - H. Clinico, Salamanca, Not set

Hospital Universitario Virgen del Rocio - PPDS, Sevilla, Not set

Taipei Veterans General Hospital, Beitou District, Taipei City, Not set

Taichung Veterans General Hospital, Taichung, Not set

National Taiwan University Hospital, Taipei, Zhongzheng Dist., Not set

Beatson West of Scotland Cancer Centre, Glasgow Scotland, Not set

Royal Liverpool University Hospital, Liverpool, Not set

Nottingham University Hospitals NHS Trust, Nottingham, Not set

University Hospital Southampton NHS Foundation Trust - Southampton General Hospital, Southampton, Not set

Conditions: Lymphoma, B-Cell

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