Gemcitabine in Combination With Either Cisplatin or Carboplatin in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
NCT00112710
Unknown
RATIONALE: Drugs used in chemotherapy, such as gemcitabine, cisplatin, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet known whether giving gemcitabine together with cisplatin is more effective than giving gemcitabine together with carboplatin in treating non-small cell lung cancer. PURPOSE: This randomized phase... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/23/2013
Locations: Institute of Clinical Research - Birmingham, Birmingham, England +1 locations
Conditions: Lung Cancer
Register for Updates
Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors
NCT00301782
Completed
RATIONALE: Drugs used in chemotherapy, such as cisplatin, vincristine, bleomycin, carboplatin, and etoposide phosphate, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet known which combination chemotherapy regimen is more effective in treating germ cell tumors. PURPOSE: This randomized phase II trial is studying two different combi... Read More
Gender:
MALE
Ages:
16 years and above
Trial Updated:
08/23/2013
Locations: Queen Elizabeth Hospital at University Hospital of Birmingham NHS Trust, Birmingham, England +19 locations
Conditions: Extragonadal Germ Cell Tumor, Teratoma, Testicular Germ Cell Tumor
Register for Updates
Paclitaxel and Carboplatin Followed by Cisplatin and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer
NCT00462397
Unknown
RATIONALE: Drugs used in chemotherapy, such as paclitaxel, carboplatin, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving combination chemotherapy together with radiation therapy may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving paclitaxel together with carboplatin followed by cisplatin and radiation therapy... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/23/2013
Locations: Leicester Royal Infirmary, Leicester, England +2 locations
Conditions: Cervical Cancer
Register for Updates
Extensive Small Cell Lung Cancer Treatment Using An Investigational Drug Plus Chemotherapy In Chemotherapy-Naive Adults
NCT00043927
Completed
This study will gather and compare data about the effectiveness and safety of two different treatments for extensive Small Cell Lung Cancer (SCLC) in patients who have not received previous chemotherapy. One treatment will use an investigational drug in combination with an FDA approved chemotherapy. The other treatment will use a combination of two FDA approved chemotherapy drugs.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2013
Locations: GSK Clinical Trials Call Center, Hoover, Alabama +175 locations
Conditions: Small Cell Lung Cancer
Register for Updates
Combination Chemotherapy in Treating Patients With Esophageal Cancer
NCT00041262
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which regimen of combination chemotherapy is more effective in treating esophageal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of combination chemotherapy in treating patients who are undergoing surgery for esophageal cancer.
Gender:
ALL
Ages:
All
Trial Updated:
08/09/2013
Locations: Queen Elizabeth Hospital at University Hospital of Birmingham NHS Trust, Birmingham, England
Conditions: Esophageal Cancer
Register for Updates
Bleomycin, Etoposide, and Cisplatin in Treating Patients With Metastatic Germ Cell Cancer of the Testicles
NCT00324298
Completed
RATIONALE: Drugs used in chemotherapy, such as bleomycin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet known which schedule of bleomycin is more effective when given together with etoposide and cisplatin in treating metastatic germ cell cancer of the testicles. PURPOSE: This randomized phase III trial... Read More
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
08/09/2013
Locations: Basildon University Hospital, Basildon, England +9 locations
Conditions: Drug/Agent Toxicity by Tissue/Organ, Testicular Germ Cell Tumor
Register for Updates
Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
NCT00004209
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether three courses of combination chemotherapy are more effective than six courses of combination chemotherapy for non-small cell lung cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of three courses of combination chemotherapy with that of six courses of combination chemoth... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/06/2013
Locations: Royal Marsden NHS Trust, London, England +1 locations
Conditions: Lung Cancer
Register for Updates
Combination Chemotherapy With or Without Radiation Therapy and Peripheral Stem Cell Transplant in Treating Children With Hodgkin's Lymphoma
NCT00025064
Unknown
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Peripheral stem cell transplant may be able to replace immune cells that were destroyed by chemotherapy. PURPOSE: This phase II trial is studying how well combination chemotherapy regimens with or without radiation therapy or peripheral stem cell transplant works in treating children with Hodgkin's lymphoma.
Gender:
ALL
Ages:
17 years and below
Trial Updated:
08/06/2013
Locations: Our Lady's Hospital for Sick Children, Dublin, Not set +20 locations
Conditions: Lymphoma
Register for Updates
Palliative Therapy With or Without Chemotherapy in Treating Patients With Malignant Mesothelioma
NCT00030459
Unknown
RATIONALE: Palliative therapy may help patients with advanced cancer live more comfortably. It is not yet known if palliative therapy is more effective with or without chemotherapy in treating patients who have malignant mesothelioma. PURPOSE: Randomized phase II trial to compare the effectiveness of palliative therapy with or without different chemotherapy regimens in treating patients who have malignant mesothelioma.
Gender:
ALL
Ages:
All
Trial Updated:
08/06/2013
Locations: Princess Royal Hospital, Hull, England +8 locations
Conditions: Malignant Mesothelioma
Register for Updates
Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesothelioma
NCT00075699
Completed
RATIONALE: Active symptom control may decrease chest pain, breathlessness, sweating, and general discomfort in patients with malignant pleural mesothelioma. It is not yet known if active symptom control is more effective with or without chemotherapy. PURPOSE: This randomized phase III trial is studying active symptom control and chemotherapy to see how well they work compared to active symptom control alone in treating patients with malignant pleural mesothelioma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/06/2013
Locations: Leeds General Infirmary at Leeds Teaching Hospital NHS Trust, Leeds, England +2 locations
Conditions: Malignant Mesothelioma
Register for Updates
Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors
NCT00453232
Completed
RATIONALE: Drugs used in chemotherapy, such as bleomycin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Colony-stimulating factors, such as pegfilgrastim, may increase the number of immune cells found in bone marrow or peripheral blood and may help the immune system recover from the side effects of chemotherapy. Giving combination chemotherapy together with pegfilgrastim may kill more tumor cells... Read More
Gender:
MALE
Ages:
Between 18 years and 40 years
Trial Updated:
08/06/2013
Locations: Addenbrooke's Hospital, Cambridge, England +6 locations
Conditions: Extragonadal Germ Cell Tumor, Teratoma, Testicular Germ Cell Tumor
Register for Updates
Capecitabine and Streptozocin With or Without Cisplatin in Treating Patients With Unresectable or Metastatic Neuroendocrine Tumors
NCT00602082
Completed
RATIONALE: Drugs used in chemotherapy, such as capecitabine, streptozocin, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving capecitabine together with streptozocin is more effective with or without cisplatin in treating neuroendocrine tumors. PURPOSE: This randomized phase II trial is studying giving capecitabine together with streptozocin to see how well it works compared w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/06/2013
Locations: Basildon University Hospital, Basildon, England +16 locations
Conditions: Gastrointestinal Carcinoid Tumor, Islet Cell Tumor
Register for Updates