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Semaglutide Treatment Options in United Kingdom
A collection of 63 research studies where Semaglutide is the interventional treatment. These studies are located in the United Kingdom . Semaglutide is used for conditions such as Diabetes Mellitus, Type 2, Obesity and Diabetes.
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A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)
Active Not Recruiting
This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.
Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance.
The study will last for up to 173 weeks (about 3 years and 4 months). Participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans. At 10... Read More
This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.
Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance.
The study will last for up to 173 weeks (about 3 years and 4 months). Participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans. At 10 of the clinic visits participants will have blood samples taken.
Participants must have a study partner, who is willing to take part in the study.
Women cannot take part if pregnant, breastfeeding or plan to become pregnant during the study period.
A cerebrospinal fluid (CSF) sub-study will be performed as a part of the study. The sub-study will be performed on a selection of sites based on their experience with CSF sampling and willingness to participate in this sub-study. The endpoints related to this sub-study are exploratory only. Read Less
Gender:
ALL
Ages:
Between 55 years and 85 years
Trial Updated:
06/24/2025
Locations: Banner Alzheimer's Institute, Phoenix, Arizona +389 locations
Banner Alzheimer's Institute, Phoenix, Arizona
Banner Sun Health Research Institute, Sun City, Arizona
Advanced Research Center, Inc., Anaheim, California
Torrance Clin Res Inst, Inc., Lomita, California
ASCLEPES Research Centers,, Long Beach, California
Well Care Medical Center, Panorama City, California
Cedars-Sinai Medical Center, Pasadena, California
Sharp Neurocog Res Ctr, San Diego, California
Syrentis Clinical Research, Santa Ana, California
Calfornia Neurosc Resrch Med, Sherman Oaks, California
Mountain Neurological Research Center, Inc., Basalt, Colorado
Denver Neurological Research, Denver, Colorado
Mile High Research Center, Denver, Colorado
Nuvance Health, Associtd Neuro, Danbury, Connecticut
Research Center for Clinical Studies, Inc, Norwalk, Connecticut
JEM Research Institute, Atlantis, Florida
Visionary Investigators Network, Aventura, Florida
Brain Matters Research, Delray Beach, Florida
Neuropsychiatric Research Cent, Fort Myers, Florida
Finlay Medical Research Group, Greenacres City, Florida
Indago Research & Health Center Inc., Hialeah, Florida
Hlth Cr Family Rehab & Res Ctr, Hialeah, Florida
Galiz Research, Hialeah, Florida
K2 Medical Research, Maitland, Maitland, Florida
Hlth Cr Family Rehab & Res Ctr, Miami, Florida
Premier Clin Res Inst, Inc., Miami, Florida
Premier Clinical Research Institute, Inc., Miami, Florida
Central Miami Medical Institute, Miami, Florida
Novel Clinical Research Center, LLC, Miami, Florida
IMIC, Inc- Medical Research, Miami, Florida
The Neurology Research Group, Miami, Florida
Visionary Inv Ntwrk_Miami, Miami, Florida
Aqualane Clinical Research, Naples, Florida
Suncoast Clinical Research, Inc._New Port Richey, New Port Richey, Florida
K2 Medical Research - Winter Garden, Ocoee, Florida
Advanced Research Consultants, Inc., Palm Beach Gardens, Florida
Intercoastal Medical Group, Sarasota, Florida
Brain Matters Resrch Kane Cntr, Stuart, Florida
Axiom Clinical Research of Florida, Tampa, Florida
Stedman Clinical Trials LLC, Tampa, Florida
Conquest Research, Winter Park, Florida
iResearch Atlanta, LLC, Decatur, Georgia
Hawaii Neuroscience, Memory Disorders Center, Honolulu, Hawaii
Velocity Clinical Research, Meridian, Meridian, Idaho
Velocity Clinical Research, Meridian, Idaho
Josephson Wallack Munshower, Indianapolis, Indiana
Cotton-O'Neil Clinical Research Center, Topeka, Kansas
University of Kentucky_Lexington_0, Lexington, Kentucky
Northern Light Eastern Maine Medical Center, Bangor, Maine
HealthPartners Center for Memory and Aging, Saint Paul, Minnesota
Hattiesburg Clinic, Hattiesburg, Mississippi
Wr-Crcn, Llc, Las Vegas, Nevada
Patient First MD,clinical Trials, Middletown, New Jersey
Advanced Memory Research Institute of NJ, Toms River, New Jersey
Neurological Assoc Long Island, Lake Success, New York
Feinstein Institute for Medical Research, Manhasset, New York
Richmond Behavioral Associates, Staten Island, New York
SUNY Upstate Medical University_Syracuse, Syracuse, New York
New Hope Clinical Research, Charlotte, North Carolina
AMC Research, LLC, Matthews, North Carolina
NeuroScience Research Center, LLC, Canton, Ohio
Insight Clinical Trials LLC, Independence, Ohio
Cleveland Clinic_Lakewood, Lakewood, Ohio
Central States Research, LLC, Tulsa, Oklahoma
Summit Research Network Oregon Inc., Portland, Oregon
Neural Net Research, LLC, Portland, Oregon
Coastal Neurology, Port Royal, South Carolina
Palmetto Clinical Research, Summerville, South Carolina
Genesis Neuroscience Clinic, Knoxville, Tennessee
Vanderbilt Medical Center, Nashville, Tennessee
Texas Diabetes & Endocrinology, Austin, Texas
Balyor College of Medicine, Houston, Texas
Univ Of Texas Hlth Science Cntr, Houston, Texas
Mt. Olympus Medical Research, Katy, Texas
Glenn Biggs Inst-Alzhm Neuro, San Antonio, Texas
Shirzadi Shahin, MD, Sugar Land, Texas
Memory Clinic, Inc, Bennington, Vermont
Integrated Neurology Services, Falls Church, Virginia
Booth Gardner Parkinson's Cre, Kirkland, Washington
Harborview Medical Center, Seattle, Washington
Instituto Medico Especializado_Capital Federal, Ciudad de Buenos Aires, Buenos Aires
Instituto de Investigaciones Metabolicas (IDIM), Buenos Aires, Not set
Hospital Italiano, Buenos Aires, Not set
Clínica Nuestra Señora de las Nieves, Caba, Not set
FLENI, Caba, Not set
Instituto Privado Kremer, Córdoba, Not set
Fundación Scherbovsky, Mendoza, Not set
St Vincent's Hospital, Darlinghurst, New South Wales
HammondCare Greenwich, Greenwich, New South Wales
Southern Neurology, Kogarah, New South Wales
KaRa Institute of Neurological Disease Pty Ltd, Macquarie Park, New South Wales
Hunter New England Local Health District - Neuropsychiatry, Waratah, New South Wales
The Prince Charles Hospital, Chermside, Queensland
Medical and Cognitive Research Unit - Austin Health, Ivanhoe, Victoria
HammondCare, Malvern, Victoria
Alzheimer's Research Australia, Nedlands, Western Australia
Australian Alzheimer's Research Foundation Incorporated, Nedlands, Western Australia
LKH-Univ. Kliniken Innsbruck, Innsbruck, Not set
Medizinische Univ. Innsbruck, Innsbruck, Not set
Univ. Klinik für Neurologie, Salzburg, Not set
Medizinische Universität Wien, Wien, Not set
UZA - UZ Antwerpen - Department of Neurology, Edegem, Not set
UZ Gent - Neurologie, Gent, Not set
AZ Groeninge - Kortrijk - Neurologie, Kortrijk, Not set
UZ Leuven - Geheugenkliniek, Leuven, Not set
Clinique CHC MontLégia - Service Neurologie, Liège, Not set
L2 IP Instituto de Pesquisas Clinicas Ltda, Brasília, Distrito Federal
Instituto de Neurologia de Curitiba, Curitiba, Parana
Clinica Clinilive Ltda, Maringa, Parana
Núcleo de Pesquisa Clínica do Rio Grande do Sul Ltda., Porto Alegre, Rio Grande Do Sul
CPQuali Pesquisa Clínica Ltda, São Paulo, Sao Paulo
BR Trials - Ensaios Clínicos e Consultoria Ltda., São Paulo, Sao Paulo
Centro de Psiquiatria Sandra Rushel, Rio de Janeiro, Not set
"MHATNP "Sv. Naum"" EAD, Sofia, Not set
DCC Sv. Vrach and Sv. Sv. Kuzma and Damyan, Sofia, Not set
"UMHAT "Aleksandrovska", Neurology clinic, Sofia, Not set
MMA, MHAT-Sofia, Neurology clinic, Sofia, Not set
OCT Research ULC (dba Okanagan Clinical Trials), Kelowna, British Columbia
Island Health (Research and Capacity Building), Victoria, British Columbia
Medical Arts Health Research Group, West Vancouver, British Columbia
True North Clinical Research - Halifax, Halifax, Nova Scotia
True North Clinical Research - New Minas, New Minas, Nova Scotia
Recherches Neuro-Hippocampe Inc, Ottowa, Ontario
Kawartha Centre Redefining Healthy Aging, Peterborough, Ontario
Memory Program, Toronto, Ontario
Centricity Research LMC, Toronto, Ontario
Sunnybrook Health Sciences Centre, Toronto, Ontario
St. Michael's Hospital, Toronto, Ontario
St. Michael's Hospital, Toronto, Ontario
University Health Network, Toronto, Ontario
MoCA Research Innovation Inc, Greenfield-Park, Quebec
Douglas Hosp Res Ctr, Montréal, Quebec
CHU de Quebec-Universite Laval, Québec, Quebec
Diex Recherche Sherbrooke Inc., Sherbrooke, Quebec
Beijing Chao-Yang Hospital, Capital Medical University-Neuro, Beijing, Beijing
Beijing Friendship Hospital, Capital Medical University-Neurology, Beijing, Beijing
Beijing Hospital-Neurology, Beijing, Beijing
Xuanwu Hospital Capital Medical University-Neurology, Beijing, Beijing
Beijing Tiantan Hospital, Capital Medical University-Neurology Center, Beijing, Beijing
Beijing An Ding Hospital Capital Medical University-Geriatric Psychiatry, Beijing, Beijing
Peking University Sixth Hospital-Geriatrics, Beijing, Beijing
Beijing Huilongguan Hospital-Geriatrics, Beijing, Beijing
Peking Union Medical College Hospital-Neurology, Beijing, Beijing
The First Affiliated Hospital of Chongqing Medical University-Geriatrics, Chongqing, Chongqing
Fujian Medical University Union Hospital-Neurology, Fuzhou, Fujian
Sun Yat-sen Memorial Hospital, Sun Yat-sen University-Neurol, Guangzhou, Guangdong
Guangzhou First People's Hospital-Neurology, Guangzhou, Guangdong
The Second affiliated hospital of Guangzhou Medical University-Neurology, Guangzhou, Guangdong
Henan Provincial People's Hospital-Neurology, Zhengzhou, Henan
Xiangya Hospital Central South University-Neurology, Changsha, Hunan
Baogang Hospital of Inner Mongolia-Neurology, Baotou, Inner Mongolia
Nanjing Brain Hospital-Neurology, Nanjing, Jiangsu
Nanjing Drum Tower Hospital-Neurology, Nanjing, Jiangsu
Zhongda Hospital Southeast University-Nephrology, Nanjing, Jiangsu
Wuxi Mental Health Center, Wuxi, Jiangsu
Northern Jiangsu People's Hospital-Neurology, Yangzhou, Jiangsu
The Second Affiliated Hospital of Nanchang University-Neurol, Nanchang, Jiangxi
The First Bethune Hospital of Jilin University, Neurology, Changchun, Jilin
Qinghai Provincial People's Hospital-Geriatrics, Xining, Qinghai
Huashan Hospital Fudan University-Neurology, Shanghai, Shanghai
Dongfang Hospital Affiliated to Shanghai Tongji University-Neurology, Shanghai, Shanghai
Shanghai 6th People's Hosp. Affili. to SHJT Univer-Neurology, Shanghai, Shanghai
Shanghai Sixth People's Hospital Affiliated to Shanghai JiaoTong University-Neurology, Shanghai, Shanghai
West China Hospital Sichuan University-Mental health center, Chengdu, Sichuan
General Hospital of Tianjin Medical University-Neurology, Tianjin, Tianjin
Tianjin Huanhu Hospital-Neurology, Tianjin, Tianjin
The First Affiliated Hospital of Zhejiang University School of Medicine-Neurology, Hangzhou, Zhejiang
Poliklinika Solmed, Zagreb, Grad Zagreb
KBC Zagreb, Klinika za neurologiju, Zagreb, Not set
Poliklinika Bonifarm, Zagreb, Not set
Neuro Health Centrum s.r.o., Brno-Lisen, Not set
AGE Centrum, Olomouc, Not set
AD71 s.r.o., Praha 10, Not set
Neuropsychiatrie, Praha 6 Dejvice, Not set
Vestra Clinics s.r.o., Rychnov nad Kneznou, Not set
Aarhus Universitetshospital, Aarhus N, Not set
Rigshospitalet - afsnit 8015, København Ø, Not set
Sjællands Universitetshospital_Roskilde, Roskilde, Not set
CRST Helsinki, Helsinki, Not set
Aivotutkimusyksikkö, Kuopio, Not set
CRST Turku, Turku, Not set
Centre Hospitalier Universitaire de Bordeaux-Hopital Pellegrin, Bordeaux, Not set
Hospices Civils de Lyon-Hopital Pierre Wertheimer, Bron, Not set
Centre Hospitalier Universitaire de Dijon-Hopital Le Bocage, Dijon, Not set
Assistance Publique Hopitaux de Marseille-Hopital de La Timone-1, Marseille, Not set
Centre Hospitalier Universitaire de Nice-Institut Claude Pompidou, Nice, Not set
Aphp-Hopital Lariboisiere-1, Paris, Not set
Aphp-Hopital La Pitie Salpetriere-3, Paris, Not set
Centre Hospitalier Universitaire Reims-Hopital Maison Blanche, Reims cedex, Not set
Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-2, Saint Herblain, Not set
Les Hopitaux Universitaires de Strasbourg-Hopital de La Robertsau, Strasbourg, Not set
Centre Hospitalier Universitaire de Toulouse-Hopital La Grave, Toulouse, Not set
Hospices Civils de Lyon-Hopital Des Charpennes, Villeurbanne, Not set
Universitätsklinikum Köln - Klinik und Poliklinik für Psychiatrie und Psychotherapie, Köln, Not set
Universitätsklinikum Münster, Neurologie, Münster, Not set
Henry Dunant Hospital Center,2nd Neurological Department, Athens, Not set
Aiginitio Hospital, 1st Neurology Clinic, Athens, Not set
"Hygeia" General Hospital of Athens, Memory clinic, Athens, Not set
Naval Hospital of Athens, Athens, Not set
Aiginitio Hospital, 1st Neurology Clinic, Athens, Not set
University General Hospital of Athens "Attiko", Chaidari, Athens, Not set
AHEPA General University Hospital, Thessaloniki, Not set
EUROMEDICA General Clinic of Thessaloniki,Neurology Dpt, Thessaloniki, Not set
Clinexpert Egészségügyi Szolgáltató és Kereskedelmi Kft., Budapest, Not set
Semmelweis Egyetem ÁOK, Budapest, Not set
DE Kenézy Gyula Campus, Pszichiátriai és Pszichoterápiai Klinika, Debrecen, Not set
DE Gyógyszerfejlesztési Koordinációs Központ Pszichiátria, Debrecen, Not set
Petz Aladar Megyei Korhaz, Gyor, Not set
Petz Aladar Megyei Oktato Korhaz, Gyor, Not set
Bugát Pál Kórház, Gyöngyös, Not set
Somogy Megyei Kaposi Mór Oktató Kórház, Kaposvár, Not set
Psychotech Kft., Pécs, Not set
Belvárosi Egészségház Kft., Zalaegerszeg, Not set
St Vincent's University Hospital, Dublin, Not set
Mercer's Institute for Successful Aging, Dublin, Not set
Tallaght University Hospital, Dublin, Not set
The Stroke and Cognition Institute Rambam Medical Center, Haifa, Not set
Cognitive Neurology Clinic, Rabin Campus, Beilinson Hospital, Petach Tikva, Not set
Cognitive Neurology Sourasky Medical Center, Tel Aviv, Not set
Chaim Sheba Medical Center, Heart Screening Clinic, 1st floor, Room 317, Tel Hashomer, Ramat Gan, Not set
AOU Ospedali Riuniti S.O.D, Ancona, Not set
Azienda Ospedaliera Spedali Civili di Brescia, Brescia, Not set
Università degli studi Gabriele D'Annunzio Chieti-Pescara, Chieti, Not set
AOU Careggi Firenze, Firenze, Not set
Fondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, Milano, Not set
IRCCS Ospedale San Raffaele Milano, Milano, Not set
ASST Monza e Brianza Ospedale San Gerardo, Monza, Not set
Ospedale Santa Maria della Misericordia, Perugia, Not set
Pol. Uni. Campus Biomedico UOC Neurologia, Roma, Not set
Policlinico Tor Vergata, Roma, Not set
Policlinico Universitario A.Gemelli Servizio Neuropsicologia, Roma, Not set
Fondazione Santa Lucia IRCCS, Roma, Not set
AOU Città della Salute e della Scienza di Torino, Torino, Not set
Iwaki Clinic_Psychosomatic medicine, Anan, Tokushima, Not set
Memory Clinic Ochanomizu, Bunkyo-ku, Tokyo, Not set
Tokyo Medical And Dental University Hospital, Bunkyo-ku,Tokyo, Not set
Kashiwado Hospital, Chib-shi, Chiba, Not set
Enomoto Internal Medicine Clinic, Chofu-shi,Tokyo, Not set
Shinozuka Hospital, Fujioka-Shi, Gunma, Not set
P-one Clinic, Hachioji-shi, Tokyo, Not set
National Hospital Organization Tenryu Hospital, Hamamatsu-shi, Shizuoka, Not set
Hyogo Brain and Heart Center, Himeji-city, Hyogo, Not set
Tsukazaki Hospital, Himeji-shi, Hyogo, Not set
Himeji Central Hospital Clinic, Himeji-shi, Hyogo, Not set
Hatsuta Neurology Clinic, Hirakata-Shi,Osaka, Not set
Imon Yukari Neurology Clinic, Hiroshima-shi, Hiroshima, Not set
Hikaru-kai Medical Corporation Hiroshima Neurology Clinic, Hiroshima-shi, Hiroshima, Not set
Hiroshima Neurology Clinic, Hiroshima-shi, Hiroshima, Not set
Nagamitsu Clinic, Hofu-shi, Yamaguchi, Not set
Ina Central Hospital, Ina-shi, Nagano, Not set
Kawasaki Saiwai Clinic_Internal Medicine, Kanagawa, Not set
Kishiro Mental Clinic, Kawasaki-shi , Kanagawa, Not set
Koukan Clinic, Kawasaki-shi, Kanagawa, Not set
Teikyo University Hospital, Mizonokuchi_Kawasaki-shi, Kanagawa, Kawasaki-shi, Kanagawa, Not set
Kobe University Hospital_Kobe-shi, Hyogo, Kobe-shi, Hyogo, Not set
National Center of Neurology and Psychiatry, Kodaira-shi, Tokyo, Not set
Southern Tohoku Medical Clinic, Koriyama-shi, Fukushima, Not set
Katayama Medical Clinic, Kurashiki-shi, Okayama, Not set
Nozomi Memory Clinic, Mitaka-shi,Tokyo, Not set
Kikukawa clinic, Nerima-ku, Tokyo, Not set
General Rehabilitation Center · Midori Hospital, Niigata-shi, Niigata, Not set
National Center for Geriatrics and Gerontology, Obu-shi, Aichi, Not set
Jichiidai Station Brain Clinic, Shimotsuke-shi, Tochigi, Not set
Keio University Hospital, Shinjuku-ku, Tokyo, Not set
Kagawa Prefectural Central Hospital_Takamatsu-shi, Kagawa, Takamatsu-shi, Kagawa, Not set
Takatsuki General Hospital, Takatsuki-Shi, Osaka, Not set
Saino Clinic, Tokorozawa-shi,Saitama, Not set
Itsuki Hospital, Tokushima-shi, Tokushima, Not set
Alzclinic Tokyo, Tokyo, Not set
Tokyo Center Clinic, Tokyo, Not set
Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Not set
Kurumi CLINIC, Tokyo, Not set
Tokyo Medical Univ. Hospital, Tokyo, Not set
Memory Clinic Toride, Toride-shi, Ibaraki, Not set
MI Clinic, Toyonaka-shi, Osaka, Not set
Medical Corporation Midorikai Wako Hospital, Wako-shi, Saitama, Not set
Dong-A University Medical Center, Busan, Not set
Chungnam National University Hospital, Daejeon, Not set
Chonnam National University Hospital, Gwangju, Not set
Seoul National University Bundang Hospital, Gyeonggi-do, Not set
Gachon University Gil Medical Center, Incheon, Not set
Inha University Hospital, Incheon, Not set
Hanyang University Medical Center, Seoul, Not set
Hanyang university seoul hospital, Seoul, Not set
Konkuk University Medical Center, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center_Seoul, Seoul, Not set
Ewha Womans University Seoul Hospital, Seoul, Not set
Amphia Ziekenhuis, Breda, Not set
Brain Research Center, Den Bosch, Not set
Radboudumc, Nijmegen, Not set
Linden sp. z o.o. sp. k., Kraków, Małopolskie
Centrum Medyczne Neuromed, Bydgoszcz, Not set
Centrum Zdrowia Psychicznego Biomed, Kielce, Not set
Szpital Uniwersytecki w Krakowie od. Neurologii, Kraków, Not set
Centrum Neurologii Klinicznej, Kraków, Not set
Nzoz Neuromed, Lublin, Not set
INSTYTUT ZDROWIA DR BOCZARSKA-JEDYNAKSp. z o.o. Sp. k., Oswiecim, Not set
NZOZ NEURO - KARD Ilkowski i Partnerzy Sp. Part. Lekarzy, Poznan, Not set
Osrodek Alzheimerowski Sp. z o.o., Scinawa, Not set
Centrum Medyczne SENIOR, Sopot, Not set
Centrum Medyczne Neuro Protect, Warszawa, Not set
NZOZ Wrocławskie Centrum Alzheimerowskie, Wroclaw, Not set
Unidade Local De Saude De Matosinhos E.P.E., Senhora Da Hora, Matosinhos, Matosinhos
Hospital de Braga, Braga, Not set
Unidade Local de Saúde de Coimbra, E.P.E., Coimbra, Not set
Unidade Local de Saude do Alto Ave, E.P.E., Guimarães, Not set
Unidade Local De Saude De Lisboa Ocidental E.P.E. - Hospital Egas Moniz, Lisboa, Not set
Hospital Beatriz Ângelo, Loures, Not set
Unidade Local de Saúde de Santo António, E.P.E, Porto, Not set
Campus Neurologico Senior, Torres Vedras, Not set
Spitalul Clinic Cai Ferate Constanta, Constanta, Not set
Spitalul Clinic Judetean De Urgenta Sfantul Apostol Andrei Constanta, Constanta, Not set
Aria Clinic SRL, Sibiu, Not set
SAHI SR "Sverdlovsk Regional Clinical Psychiatric Hospital", Ekaterinburg, Not set
Joint Stock Company "Medical technologies", Ekaterinburg, Not set
FSAEI 1st Moscow Federal Med University na Sechenov, Moscow, Not set
RMAPE, Moscow, Not set
Pirogov Russian National Research Medical University MoH, Moscow, Not set
Ezramed Clinic Llc, Omsk, Not set
Research Center for Treatment and Rehabilitation "Phoenix", Rostov-on-Don, Not set
Psychiatric hospital of st. Nicholas the wonderworker, Saint Petersburg, Not set
N.-E. State Medical University n.a. Mechnikov, Saint Petersburg, Not set
Center of Clinica Trials "Nebbiolo", Tomsk, Not set
LLC "Clinic Stolet", Tomsk, Not set
National medical holdiNational medical holding "Medstandard", Ufa, Not set
Neurology clinic, University Clinical Center of Serbia, Belgrade, Not set
Special Hospital for Psychiatric Disorders "Kovin", Kovin, Not set
University clinical center of Vojvodina, Neurology clinic, Novi Sad, Not set
I. neurologicka klinika LF UK a UNB, Bratislava, Not set
Psychiatricka klinika LF UK a UNB, Bratislava, Not set
Neurologicka klinika UPJS LF a UNLP, Kosice, Not set
NEURES, neurologicka ambulancia, Krompachy, Not set
Crystal Comfort s.r.o., Vranov nad Toplou, Not set
UKC Ljubljana, Department of Neurology, Ljubljana, Not set
UKC Maribor - neurology, Maribor, Not set
Excellentis Clinical Trial Consultants, George, Eastern Cape
IATROS International, Bloemfontein, Free State
Dr Stanley Lipschitz Clinic Inc, Johannesburg, Gauteng
Denmar Psychiatric Hospital, Pretoria, Gauteng
ACF Neurological service, Cape Town, Western Cape
Flexivest Fourteen Research Centre, Cape Town, Western Cape
Cape Trial Centre, Cape Town, Western Cape
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Fundación ACE, Barcelona, Not set
Hospital 12 de Octubre, Madrid, Not set
Hospital Universitario Quirónsalud Madrid, Pozuelo de Alarcon, Not set
Hospital Universitari General de Catalunya, Sant Cugat del Vallès, Not set
Hospital Universitario Doctor Peset, Valencia, Not set
Minnesmottagning specialiserad Malmö, Malmö, Not set
Karolinska Universitetssjukhuset, Huddinge, Stockholm, Not set
Geriatriskt centrum, Umeå, Umeå, Not set
Spitalzentrum Biel, Biel-Bienne, Not set
Centre de la Mémoire, Genève, Not set
Centre Leenaards de la mémoire CHUV, Lausanne, Not set
Klinik für Neurologie Kantonsspital St.Gallen, St. Gallen, Not set
Chang Gung Memorial Hospital - Kaoshiung Branch, Kaohsiung City, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set
Chang Gung Memorial Hospital - Kaoshiung Branch, Kaohsiung, Not set
China Medical University Hospital, Taichung, Not set
National Cheng Kung University Hospital, Tainan City, Not set
National Cheng Kung University Hospital, Tainan, Not set
National Taiwan University Hospital_main, Taipei, Not set
Taipei Veteran General Hospital_Dept of Neurology, Taipei, Not set
Taipei Veteran General Hospital, Taipei, Not set
Chang Gung Memorial Hospital Linkou, Taoyuan City, Not set
Chang Gung Memorial Hospital, Linkou, Taoyuan, Not set
Hacettepe University Medical Faculty Hospital, Altindag/Ankara, Not set
Eskisehir Osmangazi University Sağlık Uygulama ve Arastirma, Eskisehir, Not set
Istanbul University Medical Faculty Neurology Department, Istanbul, Not set
Izmir Economics University Medical Point Hospital Neurology D, Izmir, Not set
Ondokuz Mayis University Saglik Uygulama ve Arastirma Merkez, Samsun, Not set
Medical Center 'Neiron', Kharkiv, Not set
Odesa Regional Medical Center for Mental Health, Odesa, Not set
Fritchie Centre, Cheltenham, Gloucestershire
Royal Cornhill Hospital, Aberdeen, Not set
RICE - The Research Institute for the Care of Older People, Bath, Not set
Dementia Research Unit,, Crowborough, Not set
Dementia Research Unit, Crowborough, Not set
Ninewells Hospital, Dundee, Not set
Western General Hospital, Edinburgh, Not set
St Pancras Clinical Research, London, Not set
St George's Hospital, London, Not set
Imperial College London - Imperial College Memory Research Centre, London, Not set
Greater Manchester Mental Health NHS Foundation Trust, Manchester, Not set
NeuroClin, Motherwell, Not set
Newcastle University, Newcastle Upon Tyne, Not set
Warneford Hospital, Oxford, Not set
Moorgreen Hospital, Southampton, Not set
Kings Hill Research Centre, Swindon, Not set
Conditions: Early Alzheimer´s Disease
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)
Active Not Recruiting
This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.
Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance.
The study will last for up to 173 weeks (about 3 years and 4 months). Participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans. At 10... Read More
This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.
Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance.
The study will last for up to 173 weeks (about 3 years and 4 months). Participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans. At 10 of the clinic visits participants will have blood samples taken.
Participants must have a study partner, who is willing to take part in the study.
Women cannot take part if pregnant, breastfeeding or plan to become pregnant during the study period.
A cerebrospinal fluid (CSF) sub-study will be performed as a part of the study. The sub-study will be performed on a selection of sites based on their experience with CSF sampling and willingness to participate in this sub-study. The endpoints related to this sub-study are exploratory only. Read Less
Gender:
ALL
Ages:
Between 55 years and 85 years
Trial Updated:
06/24/2025
Locations: Banner Alzheimer's Institute, Phoenix, Arizona +342 locations
Banner Alzheimer's Institute, Phoenix, Arizona
Imaging Endpoints, Scottsdale, Arizona
Banner Sun Health Research Institute, Sun City, Arizona
Advanced Research Center, Inc., Anaheim, California
Fullerton Neurology and Headache Center, Fullerton, California
Pacific Research Network, Lemon Grove, California
Torrance Clin Res Inst, Inc., Lomita, California
ASCLEPES Research Centers,, Long Beach, California
UCLA_Los Angeles, Los Angeles, California
Well Care Medical Center, Panorama City, California
Cedars-Sinai Medical Center, Pasadena, California
Sharp Neurocog Res Ctr, San Diego, California
Syrentis Clinical Research, Santa Ana, California
Calfornia Neurosc Resrch Med, Sherman Oaks, California
Southern California Research LLC, Simi Valley, California
Mountain Neurological Research Center, Inc., Basalt, Colorado
Denver Neurological Research, Denver, Colorado
Mile High Research Center, Denver, Colorado
JEM Research Institute, Atlantis, Florida
Visionary Investigators Network, Aventura, Florida
Brain Matters Research, Delray Beach, Florida
Integrity Clinical Research, LLC, Doral, Florida
Neuropsychiatric Research Cent, Fort Myers, Florida
Finlay Medical Research Group, Greenacres City, Florida
Indago Research & Health Center Inc., Hialeah, Florida
Hlth Cr Family Rehab & Res Ctr, Hialeah, Florida
K2 The Villages, Lady Lake, Florida
K2 Medical Research, Maitland, Maitland, Florida
Hlth Cr Family Rehab & Res Ctr, Miami, Florida
Premier Clin Res Inst, Inc., Miami, Florida
Premier Clinical Research Institute, Inc., Miami, Florida
Novel Clinical Research Center, LLC, Miami, Florida
IMIC, Inc- Medical Research, Miami, Florida
The Neurology Research Group, Miami, Florida
Visionary Inv Ntwrk_Miami, Miami, Florida
Aqualane Clinical Research, Naples, Florida
Suncoast Clin Res Port Richey, New Port Richey, Florida
Suncoast Clinical Research, Inc._New Port Richey, New Port Richey, Florida
Combined Research Orlando Phase I-IV, Orlando, Florida
Advanced Research Consultants, Inc., Palm Beach Gardens, Florida
Intercoastal Medical Group, Sarasota, Florida
The Roskamp Institute, Inc., Sarasota, Florida
Axiom Clinical Research of Florida, Tampa, Florida
Stedman Clinical Trials LLC, Tampa, Florida
Palm Beach Neuro Premiere Res, West Palm Beach, Florida
Conquest Research, Winter Park, Florida
Center for Adv Res & Education, Gainesville, Georgia
Hawaii Neuroscience, Memory Disorders Center, Honolulu, Hawaii
Velocity Clinical Research, Meridian, Meridian, Idaho
Velocity Clinical Research, Meridian, Idaho
Cotton-O'Neil Clinical Research Center, Topeka, Kansas
University of Kentucky_Lexington_0, Lexington, Kentucky
Northern Light Eastern Maine Medical Center, Bangor, Maine
HealthPartners Center for Memory and Aging, Saint Paul, Minnesota
Hattiesburg Clinic, Hattiesburg, Mississippi
Patient First MD,clinical Trials, Middletown, New Jersey
Advanced Memory Research Institute of NJ, Toms River, New Jersey
Neurological Assoc Long Island, Lake Success, New York
Richmond Behavioral Associates, Staten Island, New York
New Hope Clinical Research, Charlotte, North Carolina
AMC Research, LLC, Matthews, North Carolina
Insight Clinical Trials LLC, Beachwood, Ohio
Central States Research, LLC, Tulsa, Oklahoma
Summit Research Network Oregon Inc., Portland, Oregon
The Clinical Trial Center, Jenkintown, Pennsylvania
Coastal Neurology, Port Royal, South Carolina
Genesis Neuroscience Clinic, Knoxville, Tennessee
Vanderbilt Medical Center, Nashville, Tennessee
Univ Of Texas Hlth Science Cntr, Houston, Texas
Glenn Biggs Inst-Alzhm Neuro, San Antonio, Texas
Shirzadi Shahin, MD, Sugar Land, Texas
Integrated Neurology Services, Falls Church, Virginia
Instituto Medico Especializado_Capital Federal, Ciudad de Buenos Aires, Buenos Aires
Instituto de Investigaciones Metabolicas (IDIM), Buenos Aires, Not set
Hospital Italiano, Buenos Aires, Not set
Clínica Nuestra Señora de las Nieves, Caba, Not set
FLENI, Caba, Not set
Instituto Privado Kremer, Córdoba, Not set
Fundación Scherbovsky, Mendoza, Not set
St Vincent's Hospital, Darlinghurst, New South Wales
Southern Neurology, Kogarah, New South Wales
Hunter New England Local Health District - Neuropsychiatry, Waratah, New South Wales
The Prince Charles Hospital, Chermside, Queensland
Medical and Cognitive Research Unit - Austin Health, Ivanhoe, Victoria
LKH-Univ. Kliniken Innsbruck, Innsbruck, Not set
Medizinische Univ. Innsbruck, Innsbruck, Not set
Univ. Klinik für Neurologie, Salzburg, Not set
UZA - UZ Antwerpen - Department of Neurology, Edegem, Not set
AZ Groeninge - Kortrijk - Neurologie, Kortrijk, Not set
L2 IP Instituto de Pesquisas Clinicas Ltda, Brasília, Distrito Federal
Instituto de Neurologia de Curitiba, Curitiba, Parana
Clinica Clinilive Ltda, Maringa, Parana
Núcleo de Pesquisa Clínica do Rio Grande do Sul Ltda., Porto Alegre, Rio Grande Do Sul
CPQuali Pesquisa Clínica Ltda, São Paulo, Sao Paulo
BR Trials - Ensaios Clínicos e Consultoria Ltda., São Paulo, Sao Paulo
Assoc. Paulista para o Desenvolvimento da Medicina - UNIFESP, São Paulo, Sao Paulo
Centro de Psiquiatria Sandra Rushel, Rio de Janeiro, Not set
"MHATNP "Sv. Naum"" EAD, Sofia, Not set
DCC Sv. Vrach and Sv. Sv. Kuzma and Damyan, Sofia, Not set
"UMHAT "Aleksandrovska", Neurology clinic, Sofia, Not set
MMA, MHAT-Sofia, Neurology clinic, Sofia, Not set
OCT Research ULC (dba Okanagan Clinical Trials), Kelowna, British Columbia
Medical Arts Health Research Group_Kelowna, Penticton, British Columbia
Island Health (Research and Capacity Building), Victoria, British Columbia
True North Clinical Research - Halifax, Halifax, Nova Scotia
True North Clinical Research - New Minas, New Minas, Nova Scotia
Ottawa Memory Clinic, Ottawa, Ontario
Recherches Neuro-Hippocampe Inc, Ottowa, Ontario
Memory Program, Toronto, Ontario
Centricity Research LMC, Toronto, Ontario
Sunnybrook Health Sciences Centre, Toronto, Ontario
University Health Network - Toronto Western Hospital, Toronto, Ontario
University Health Network, Toronto, Ontario
Douglas Hosp Res Ctr, Montréal, Quebec
CHU de Quebec-Universite Laval, Québec, Quebec
Neuro Health Centrum s.r.o., Brno-Lisen, Not set
AGE Centrum, Olomouc, Not set
AD71 s.r.o., Praha 10, Not set
Neuropsychiatrie, Praha 6 Dejvice, Not set
Vestra Clinics s.r.o., Rychnov nad Kneznou, Not set
Aarhus Universitetshospital, Aarhus N, Not set
Rigshospitalet - afsnit 8015, København Ø, Not set
Sjællands Universitetshospital_Roskilde, Roskilde, Not set
CRST Helsinki, Helsinki, Not set
Aivotutkimusyksikkö, Kuopio, Not set
CRST Turku, Turku, Not set
Centre Hospitalier Universitaire de Bordeaux-Hopital Pellegrin, Bordeaux, Not set
Hospices Civils de Lyon-Hopital Pierre Wertheimer, Bron, Not set
Centre Hospitalier Universitaire de Dijon-Hopital Le Bocage, Dijon, Not set
Hôpital Roger Salengro, Lille CEDEX, Not set
Assistance Publique Hopitaux de Marseille-Hopital de La Timone-1, Marseille, Not set
Centre Hospitalier Universitaire de Nice-Institut Claude Pompidou, Nice, Not set
Aphp-Hopital Lariboisiere-1, Paris, Not set
Aphp-Hopital La Pitie Salpetriere-3, Paris, Not set
Centre Hospitalier Universitaire Reims-Hopital Maison Blanche, Reims cedex, Not set
Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-2, Saint Herblain, Not set
Les Hopitaux Universitaires de Strasbourg-Hopital de La Robertsau, Strasbourg, Not set
Centre Hospitalier Universitaire de Toulouse-Hopital La Grave, Toulouse, Not set
Hospices Civils de Lyon-Hopital Des Charpennes, Villeurbanne, Not set
Zentrum für klinische Forschung Dr. med. Irma Schöll GmbH, Bad Homburg, Hessen
Universitätsklinikum RWTH Aachen, Neurologie, Aachen, Not set
Studienzentrum Dr. Bischof GmbH, Böblingen, Not set
Neuro Centrum Science GmbH, Erbach, Not set
Universitätsklinikum Hamburg-Eppendorf, Psychiatrie, Hamburg, Not set
Universitätsklinikum Köln - Klinik und Poliklinik für Psychiatrie und Psychotherapie, Köln, Not set
Universitätsmedizin Mainz, Psychiatrie, Mainz, Not set
Zentralinstitut für Seelische Gesundheit - Psychiatrie und Psychotherapie, Mannheim, Not set
LMU Klinikum - Institut für Schlaganfall- und Demenzforschung (ISD), München, Not set
Universitätsklinikum Ulm, Neurologie, Ulm, Not set
Studienzentrum Nord-West, Westerstede, Not set
Henry Dunant Hospital Center,2nd Neurological Department, Athens, Not set
Aiginitio Hospital, 1st Neurology Clinic, Athens, Not set
"Hygeia" General Hospital of Athens, Memory clinic, Athens, Not set
Naval Hospital of Athens, Athens, Not set
University General Hospital of Athens "Attiko", Chaidari, Athens, Not set
Iatriko Athinon (Athens Medical Center),Memory Disorders Cli, Marousi, Not set
AHEPA General University Hospital, Thessaloniki, Not set
EUROMEDICA General Clinic of Thessaloniki,Neurology Dpt, Thessaloniki, Not set
Semmelweis Egyetem ÁOK, Budapest, Not set
DE Kenézy Gyula Campus, Pszichiátriai és Pszichoterápiai Klinika, Debrecen, Not set
DE Gyógyszerfejlesztési Koordinációs Központ Pszichiátria, Debrecen, Not set
Petz Aladar Megyei Korhaz, Gyor, Not set
Petz Aladar Megyei Oktato Korhaz, Gyor, Not set
Bugát Pál Kórház, Gyöngyös, Not set
Somogy Megyei Kaposi Mór Oktató Kórház, Kaposvár, Not set
Psychotech Kft., Pécs, Not set
Belvárosi Egészségház Kft., Zalaegerszeg, Not set
Mercy Hospital Cork, Cork, Not set
St Vincent's University Hospital, Dublin, Not set
Mercer's Institute for Successful Aging, Dublin, Not set
Tallaght University Hospital, Dublin, Not set
The Stroke and Cognition Institute Rambam Medical Center, Haifa, Not set
Cognitive Neurology Clinic, Rabin Campus, Beilinson Hospital, Petach Tikva, Not set
Cognitive Neurology Sourasky Medical Center, Tel Aviv, Not set
Chaim Sheba Medical Center, Heart Screening Clinic, 1st floor, Room 317, Tel Hashomer, Ramat Gan, Not set
AOU Ospedali Riuniti S.O.D, Ancona, Not set
Azienda Ospedaliera Spedali Civili di Brescia, Brescia, Not set
Università degli studi Gabriele D'Annunzio Chieti-Pescara, Chieti, Not set
Fondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, Milano, Not set
IRCCS Ospedale San Raffaele Milano, Milano, Not set
ASST Monza e Brianza Ospedale San Gerardo, Monza, Not set
Ospedale Santa Maria della Misericordia, Perugia, Not set
Pol. Uni. Campus Biomedico UOC Neurologia, Roma, Not set
Policlinico Tor Vergata, Roma, Not set
Policlinico Universitario A.Gemelli Servizio Neuropsicologia, Roma, Not set
Fondazione Santa Lucia IRCCS, Roma, Not set
Iwaki Clinic_Psychosomatic medicine, Anan, Tokushima, Not set
Yachiyo Hospital, Anjo-shi, Aichi, Not set
Abe Clinic, Arakawa-ku,Tokyo, Not set
Memory Clinic Ochanomizu, Bunkyo-ku, Tokyo, Not set
Tokyo Medical And Dental University Hospital, Bunkyo-ku,Tokyo, Not set
Kashiwado Hospital, Chib-shi, Chiba, Not set
Enomoto Internal Medicine Clinic, Chofu-shi,Tokyo, Not set
Shinozuka Hospital, Fujioka-Shi, Gunma, Not set
P-one Clinic, Hachioji-shi, Tokyo, Not set
National Hospital Organization Tenryu Hospital, Hamamatsu-shi, Shizuoka, Not set
Hyogo Brain and Heart Center, Himeji-city, Hyogo, Not set
Tsukazaki Hospital, Himeji-shi, Hyogo, Not set
Himeji Central Hospital Clinic, Himeji-shi, Hyogo, Not set
Hatsuta Neurology Clinic, Hirakata-Shi,Osaka, Not set
Imon Yukari Neurology Clinic, Hiroshima-shi, Hiroshima, Not set
Hikaru-kai Medical Corporation Hiroshima Neurology Clinic, Hiroshima-shi, Hiroshima, Not set
Nagamitsu Clinic, Hofu-shi, Yamaguchi, Not set
Ina Central Hospital, Ina-shi, Nagano, Not set
Kawasaki Saiwai Clinic_Internal Medicine, Kanagawa, Not set
Kishiro Mental Clinic, Kawasaki-shi , Kanagawa, Not set
Koukan Clinic, Kawasaki-shi, Kanagawa, Not set
Teikyo University Hospital, Mizonokuchi_Kawasaki-shi, Kanagawa, Kawasaki-shi, Kanagawa, Not set
Kobe University Hospital_Kobe-shi, Hyogo, Kobe-shi, Hyogo, Not set
National Center of Neurology and Psychiatry, Kodaira-shi, Tokyo, Not set
Southern Tohoku Medical Clinic, Koriyama-shi, Fukushima, Not set
Katayama Medical Clinic, Kurashiki-shi, Okayama, Not set
Nozomi Memory Clinic, Mitaka-shi,Tokyo, Not set
Kikukawa clinic, Nerima-ku, Tokyo, Not set
General Rehabilitation Center · Midori Hospital, Niigata-shi, Niigata, Not set
National Center for Geriatrics and Gerontology, Obu-shi, Aichi, Not set
Jichiidai Station Brain Clinic, Shimotsuke-shi, Tochigi, Not set
Keio University Hospital, Shinjuku-ku, Tokyo, Not set
Shizuoka City Shimizu Hospital_Neurology, Shizuoka-shi, Shizuoka, Not set
Kagawa Prefectural Central Hospital_Takamatsu-shi, Kagawa, Takamatsu-shi, Kagawa, Not set
Saino Clinic, Tokorozawa-shi,Saitama, Not set
Itsuki Hospital, Tokushima-shi, Tokushima, Not set
Alzclinic Tokyo, Tokyo, Not set
Tokyo Center Clinic, Tokyo, Not set
Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Not set
Kurumi CLINIC, Tokyo, Not set
Tokyo Medical Univ. Hospital, Tokyo, Not set
Memory Clinic Toride, Toride-shi, Ibaraki, Not set
MI Clinic, Toyonaka-shi, Osaka, Not set
Medical Corporation Midorikai Wako Hospital, Wako-shi, Saitama, Not set
Dong-A University Medical Center, Busan, Not set
Chungnam National University Hospital, Daejeon, Not set
Chonnam National University Hospital, Gwangju, Not set
Seoul National University Bundang Hospital, Gyeonggi-do, Not set
Gachon University Gil Medical Center, Incheon, Not set
Inha University Hospital, Incheon, Not set
Hanyang University Medical Center, Seoul, Not set
Hanyang university seoul hospital, Seoul, Not set
Konkuk University Medical Center, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center_Seoul, Seoul, Not set
Ewha Womans University Seoul Hospital, Seoul, Not set
Hospital Universitario "Dr. Gonzalo Valdes Valdes", Saltillo, Coahuila
Hospital Universitario Dr. José Eleuterio González_Monterrey, Monterrey, Nuevo León
Centro de Estudios Clínicos y Especialidades Médicas S.C., Monterrey, Nuevo León
Avix Investigación Clínica, S.C., Monterrey, Nuevo León
Hospital Angeles de Culiacan, Culiacan, Sinaloa
Amphia Ziekenhuis, Breda, Not set
Brain Research Center, Den Bosch, Not set
Radboudumc, Nijmegen, Not set
Akershus universitetssykehus - Hukommelsesklinikken, Lørenskog, Not set
Oslo universitetssykehus HF, Ullevål, Oslo, Not set
Master Centre - Dummy, Oslo, Not set
Linden sp. z o.o. sp. k., Kraków, Małopolskie
Centrum Medyczne Neuromed, Bydgoszcz, Not set
Centrum Zdrowia Psychicznego Biomed, Kielce, Not set
Szpital Uniwersytecki w Krakowie od. Neurologii, Kraków, Not set
Centrum Neurologii Klinicznej, Kraków, Not set
Nzoz Neuromed, Lublin, Not set
NZOZ NEURO - KARD Ilkowski i Partnerzy Sp. Part. Lekarzy, Poznan, Not set
Osrodek Alzheimerowski Sp. z o.o., Scinawa, Not set
Centrum Medyczne SENIOR, Sopot, Not set
Centrum Medyczne Neuro Protect, Warszawa, Not set
NZOZ Wrocławskie Centrum Alzheimerowskie, Wroclaw, Not set
Unidade Local De Saude De Matosinhos E.P.E., Senhora Da Hora, Matosinhos, Matosinhos
Hospital de Braga, Braga, Not set
Unidade Local de Saúde de Coimbra, E.P.E., Coimbra, Not set
Unidade Local de Saude do Alto Ave, E.P.E., Guimarães, Not set
Unidade Local De Saude De Lisboa Ocidental E.P.E. - Hospital Egas Moniz, Lisboa, Not set
Hospital Beatriz Ângelo, Loures, Not set
Unidade Local de Saúde de Santo António, E.P.E, Porto, Not set
Campus Neurologico Senior, Torres Vedras, Not set
Sana Monitoring SRL, Bucharest, Not set
Spitalul Clinic Cai Ferate Constanta, Constanta, Not set
Spitalul Clinic Judetean De Urgenta Sfantul Apostol Andrei Constanta, Constanta, Not set
Aria Clinic SRL, Sibiu, Not set
Joint Stock Company "Medical technologies", Ekaterinburg, Not set
Federal Siberian Research Clinical Center under FMBA of Rus, Krasnoyarsk, Not set
FSAEI 1st Moscow Federal Med University na Sechenov, Moscow, Not set
RMAPE, Moscow, Not set
Pirogov Russian National Research Medical University MoH, Moscow, Not set
Ezramed Clinic Llc, Omsk, Not set
Research Center for Treatment and Rehabilitation "Phoenix", Rostov-on-Don, Not set
Psychiatric hospital of st. Nicholas the wonderworker, Saint Petersburg, Not set
N.-E. State Medical University n.a. Mechnikov, Saint Petersburg, Not set
S.M. Kirov Military Medical Academy,Depart.&Clinic Nerv Dis, Saint Petersburg, Not set
Center of Clinica Trials "Nebbiolo", Tomsk, Not set
LLC "Clinic Stolet", Tomsk, Not set
National medical holdiNational medical holding "Medstandard", Ufa, Not set
Neurology clinic, University Clinical Center of Serbia, Belgrade, Not set
Special Hospital for Psychiatric Disorders "Kovin", Kovin, Not set
University clinical center of Vojvodina, Neurology clinic, Novi Sad, Not set
Psych. amb. CENTRUM ZDRAVIA R.B.K., s.r.o. Bardejov, Bardejov, Not set
I. neurologicka klinika LF UK a UNB, Bratislava, Not set
Psychiatricka klinika LF UK a UNB, Bratislava, Not set
Neurologicka klinika UPJS LF a UNLP, Kosice, Not set
Crystal Comfort s.r.o., Vranov nad Toplou, Not set
UKC Ljubljana, Department of Neurology, Ljubljana, Not set
UKC Maribor - neurology, Maribor, Not set
Excellentis Clinical Trial Consultants, George, Eastern Cape
IATROS International, Bloemfontein, Free State
Dr Stanley Lipschitz Clinic Inc, Johannesburg, Gauteng
Denmar Psychiatric Hospital, Pretoria, Gauteng
ACF Neurological service, Cape Town, Western Cape
Flexivest Fourteen Research Centre, Cape Town, Western Cape
Cape Trial Centre, Cape Town, Western Cape
Hospital Santa Creu i Sant Pau, Barcelona, Not set
Fundación ACE, Barcelona, Not set
Fundación CITA, Donostia, Not set
Hospital Ramón y Cajal, Madrid, Not set
Hospital Universitario Quirónsalud Madrid, Pozuelo de Alarcon, Not set
Hospital Universitari General de Catalunya, Sant Cugat del Vallès, Not set
Hospital Universitario Marqués de Valdecilla, Santander, Not set
Hospital Universitario Doctor Peset, Valencia, Not set
Minnesmottagning specialiserad Malmö, Malmö, Not set
Karolinska Universitetssjukhuset, Huddinge, Stockholm, Not set
Geriatriskt centrum, Umeå, Umeå, Not set
Spitalzentrum Biel, Biel-Bienne, Not set
Centre de la Mémoire, Genève, Not set
Centre Leenaards de la mémoire CHUV, Lausanne, Not set
Klinik für Neurologie Kantonsspital St.Gallen, St. Gallen, Not set
Hacettepe University Medical Faculty Hospital, Altindag/Ankara, Not set
Eskisehir Osmangazi University Sağlık Uygulama ve Arastirma, Eskisehir, Not set
Istanbul University Medical Faculty Neurology Department, Istanbul, Not set
Izmir Economics University Medical Point Hospital Neurology D, Izmir, Not set
Ondokuz Mayis University Saglik Uygulama ve Arastirma Merkez, Samsun, Not set
Chebotarev State Institute of Gerontology of the NAMS of Ukr, Kyiv, Not set
Fritchie Centre, Cheltenham, Gloucestershire
Royal Cornhill Hospital, Aberdeen, Not set
RICE - The Research Institute for the Care of Older People, Bath, Not set
Dementia Research Unit,, Crowborough, Not set
Dementia Research Unit, Crowborough, Not set
Ninewells Hospital, Dundee, Not set
Western General Hospital, Edinburgh, Not set
St Pancras Clinical Research, London, Not set
St George's Hospital, London, Not set
Imperial College London - Imperial College Memory Research Centre, London, Not set
Greater Manchester Mental Health NHS Foundation Trust, Manchester, Not set
NeuroClin, Motherwell, Not set
Newcastle University, Newcastle Upon Tyne, Not set
Warneford Hospital, Oxford, Not set
Moorgreen Hospital, Southampton, Not set
Kings Hill Research Centre, Swindon, Not set
Conditions: Early Alzheimer's Disease
Research Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non-alcoholic Steatohepatitis (NASH)
Completed
This study is being done to see if a combination of 2 medicines (called NNC0194-0499 and semaglutide) can reduce liver damage in patients with non alcoholic steatohepatitis (NASH).
NNC0194-0499 is a new medicine which works in the liver. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. It also helps with weight loss and may reduce liver damage, and so prevent future liver complications. It works in a different way to NNC0194 0499... Read More
This study is being done to see if a combination of 2 medicines (called NNC0194-0499 and semaglutide) can reduce liver damage in patients with non alcoholic steatohepatitis (NASH).
NNC0194-0499 is a new medicine which works in the liver. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. It also helps with weight loss and may reduce liver damage, and so prevent future liver complications. It works in a different way to NNC0194 0499. The 2 medicines may work better together than on their own.
The study will also look at a combination of semaglutide and another weight-loss medicine called NNC0174-0833, which may be another treatment option for NASH.
Each week, participants will get 2 injections. These could be 2 of the 3 medicines OR 1 of the medicines and a placebo OR 2 placebo injections. Which treatment participants get is decided by chance. A placebo is a dummy medicine which looks like the real medicine but doesn't contain any active medicine.
The study will last for about 19 months. Participants will have 14 clinic visits and 9 phone calls with the study doctor.
Participants will have 1 or 2 liver biopsies (tiny pieces of liver tissue) - one at the start (if participants have not had a biopsy recently) and one at the end of the study treatment.
Women: Women cannot take part if pregnant, breast-feeding or planning to become pregnant during the study period. Read Less
Gender:
ALL
Ages:
All
Trial Updated:
06/17/2025
Locations: North AL Health Res, LLC, Huntsville, Alabama +183 locations
North AL Health Res, LLC, Huntsville, Alabama
The Institute for Liver Health, Chandler, Arizona
Inst-Liver Hlth dba AZ Liver H, Peoria, Arizona
Del Sol Research Management, LLC, Tucson, Arizona
UCSD NAFLD Research Center, La Jolla, California
OM Research LLC, Lancaster, California
Stanford Medicine, Redwood City, California
UC Davis Hlth -Midtwn Ambu Cen, Sacramento, California
Peak Gastro Assoc-Col Springs, Colorado Springs, Colorado
Hartford Hsptl_Hartford, Hartford, Connecticut
Integrity Clinical Research, LLC, Doral, Florida
Miguel Rebollar PA, Hialeah, Florida
Nature Coast Clinical Research_Inverness, Inverness, Florida
UF Hlth Jacksonville, Jacksonville, Florida
Florida Research Institute, LLC, Lakewood Ranch, Florida
Optimus U, Corp, Miami, Florida
Univ of Miami/Schiff Ctr, Miami, Florida
Covenant Metabolic Specialists LLC, University Park, Florida
Florida Medical Clinic Orlando Health, Zephyrhills, Florida
Florida Medical Clinic, LLC, Zephyrhills, Florida
Piedmont Healthcare, Atlanta, Georgia
Digestive Healthcare of Georgia, Atlanta, Georgia
Gastroenterology Assoc_ CGA, Macon, Georgia
Gastroint Spec of Georgia, Marietta, Georgia
Digestive Research Alliance of Michiana, South Bend, Indiana
University Of Kansas Hospital, Kansas City, Kansas
Kansas Medical Clinic, PA, Topeka, Kansas
Tandem Clinical Research - Houma, Houma, Louisiana
Tandem Clinical Research, Marrero, Louisiana
Louisiana Research Center, LLC, Shreveport, Louisiana
Mercy Medical Center, GI Research, Baltimore, Maryland
Walter Reed Nat Mil Md Ctr, Bethesda, Maryland
Henry Ford Hospital_Detroit, Detroit, Michigan
Kansas City Research Institute, Kansas City, Missouri
AIG Digestive Disease Research, Florham Park, New Jersey
NYU Grossman School of Med, New York, New York
Weill Cornell Med Coll-NYPH, New York, New York
Univ Hosp Cleveland Med Ctr, Cleveland, Ohio
Ohio State Univ Wexner Med Ctr, Columbus, Ohio
DSI Research,LLC, Springboro, Ohio
Geisinger Clinic, Danville, Pennsylvania
Pennsylvania State University, Hershey, Pennsylvania
University of Pennsylvania Hospital, Philadelphia, Pennsylvania
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
UPMC Center for Liver Diseases, Pittsburgh, Pennsylvania
UPMC_Center for Liver Care, Pittsburgh, Pennsylvania
Digestive Health Res-TSMC, Hermitage, Tennessee
Quality Medical Research, Nashville, Tennessee
Texas Clin Res Inst, LLC, Arlington, Texas
Liver Ins@ Mthdist DTX Med Cen, Dallas, Texas
Texas Diabetes &Endocrinology, Round Rock, Texas
Amer. Rrsch Corp-TX Liver Inst, San Antonio, Texas
Olympus Clinical Research, Sugar Land, Texas
Impact Research, Waco, Texas
Digestive Hlth Res of N Texas, Wichita Falls, Texas
Inova Fairfax Medical Campus, Falls Church, Virginia
Bon Secours Richmond Community Hospital LLC, Richmond, Virginia
Gastroent Consult of SW VA, Roanoke, Virginia
Swedish med ctr org trans-lvr ctr, Seattle, Washington
Liver Institute NW, Seattle, Washington
Genesis Research Services, Broadmeadow, New South Wales
St Vincent's Hospital, Darlinghurst, New South Wales
Nepean Hospital, Kingswood, New South Wales
Westmead Hospital, Westmead, New South Wales
Royal Adelaide Hospital - Hepatology- 5E291, Adelaide, South Australia
Monash Health Department of Gastroenterology, Clayton, Victoria
St Vincent's Hospital (Melbourne), Fitzroy, Victoria
Austin Health, Heidelberg, Victoria
The Alfred Centre - Gastroenterology, Melbourne, Victoria
Fiona Stanley Hospital - Hepatology, Murdoch, Western Australia
CUB Hôpital Erasme_Brussels_0, Bruxelles, Not set
Cliniques Universitaires Saint-Luc - Serv. Hépato-gastroentérology, Bruxelles, Not set
UZA, Edegem, Not set
UZ Gent - Department Gastro-enterology, Gent, Not set
"Acibadem City Clinic UMHAT Tokuda", Sofia, Not set
UMHAT "Sv. Ivan Rilski", Clinic of Gastroenterology, Sofia, Not set
"DCC XX - Sofia" EOOD, Sofia, Not set
University of Calgary Liver Unit-(HMRC), Calgary, Alberta
GI Research Inst Foundation, Vancouver, British Columbia
Toronto Liver Centre, Toronto, Ontario
Krajská nemocice Liberec, a.s, Liberec, Not set
Hvidovre Hospital - Gastroenheden, Hvidovre, Not set
Abdominal Center K, Research Unit, København NV, Not set
Odense University Hospital, Odense C, Not set
Centre Hospitalier Universitaire D'Angers-1, Angers, Not set
Ap-Hp-Hopital Beaujon, Clichy, Not set
Hospices Civils de Lyon-Hopital de La Croix Rousse, Lyon Cedex 4, Not set
Centre Hospitalier Universitaire de Nice-Hopital de L'Archet 2, Nice, Not set
Aphp-Hopital La Pitie Salpetriere-4, Paris, Not set
Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-1, Saint Herblain, Not set
Centre de Recherche Clinique Portes Du Sud, Venissieux, Not set
Klinik für Endokrinologie, Diabetologie und Stoffwechsel, Essen, Not set
Universitätsklinikum Schleswig-Holstein - Medizinischen Klinik I am Campus Lübeck, Lübeck, Not set
Universitätsklinikum Schleswig-Holstein, Lübeck, Not set
Universitätsmedizin der Johannes-Gutenberg-Universität Mainz - Hepatologie, Mainz, Not set
Universitätsklinikum Würzburg, Zentrum für Innere Medizin (ZIM), Würzburg, Not set
Universitätsklinikum Würzburg, ZIM, Würzburg, Not set
Gen Hospital of Athens Ippokrateio,B' Uni Clinic of Inte Med, Athens, Not set
Gen Hospital of Athens Laiko,1st Dpt. of Propaedeutic Inter, Athens, Not set
Gen Hospital of Athens Laiko,1st Dpt. of Propaedeutic Inter, Athens, Not set
General Hospital of Athens "LAIKO", Goudi, Athens, Not set
"AHEPA" University Hospital of Thessaloniki, Thessaloniki, Not set
General Hospital of Thessaloniki "Ippokrateio", Thessaloniki, Not set
Yashoda Hospital, Secunderabad, Andhra Pradesh
Surat Institute of Digestive Science, Surat, Gujarat
BAPS Pramukh Swami Hospital, Surat, Gujarat
Medanta - The Medicity Multi-Speciality Hospital, Gurugram, Gurugram, Haryana
Kasturba Medical College Hospitals (KMC Hospitals), Mangalore, Mangalore, Karnataka
Gleneagles Hospital, Super-speciality and Transplant Centre, Parel, Mumbai, Maharashtra
Seth GS medical college and KEM Hospital, Mumbai, Maharashtra
Midas Multispeciality Hospital, Nagpur, Maharashtra
Institute of liver and Biliary Sciences, Ghitorni, New Delhi
All India Institute of medical Sciences, New Dehli, New Delhi
Fortis Heart Institute and Multispeciality Hospital, Chandigarh,, Punjab
Post Graduate Institute of Medical Education & Research_Chandigarh, Chandigarh, Punjab
S.R.Kalla Memorial Gastro & General Hospital, Jaipur, Rajasthan
Osmania General Hospital, Hyderabad, Telagana
Dr P V Rao - Diabetes Research Centre, Hyderabad, Telangana
Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona, Ancona, Not set
Azienda Socio Sanitaria Territoriale (ASST) Papa Giovanni XXIII, Bergamo, Not set
Azieda Ospedaliero-Universitaria, Policlinico S. Orsola-Malp, Bologna, Not set
AOU Careggi Padiglione 16 San Luca, 3° piano, Firenze, Not set
Azienda Ospedaliera di Padova Clin.Med.3, Padova, Not set
AOU Pisana Stabilimento di Cisanello EDIFICIO 6, Piano 5, Pisa, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Not set
Policlinico Università Campus Biomedico di Roma, Rome, Not set
Chiba University Hospital_Chiba-shi, Chiba, Chiba-shi, Chiba, Not set
Fukui-ken Saiseikai Hospital, Internal Medicine, Fukui-shi, Fukui, Not set
Hamamatsu University Hospital, Hamamatsu-shi, Shizuoka, Not set
JA Hiroshima General Hospital, Hatsukaichi-shi, Hiroshima, Not set
University Hospital Kyoto Prefectual University of Medicine, Kamigyo-ku, Kyoto, Not set
St. Marianna University School of Medicine Hospital, Kawasaki-shi, Kanagawa, Not set
Kumamoto Shinto General Hospital, Kumamoto-shi, Kumamoto, Not set
Toranomon Hospital, Hepatology, Minato-ku, Tokyo, Not set
Kawasaki Medical School General Medical Center, Okayama-shi, Okayama, Not set
Saga University Hospital_Liver Center, Saga-shi, Saga, Not set
Sendai Kousei Hospital, Sendai-shi, Miyagi, Not set
Saiseikai Suita Hospital, Gastroenterology, Suita-shi, Osaka, Not set
Ehime University Hospital, Toon-shi, Ehime, Not set
Saiseikai Wakayama Hospital, Wakayama-shi, Wakayama, Not set
Yokohama City University Hospital, Gastrointestinal Medicine, Yokohama-shi, Kanagawa, Not set
Korea University Ansan Hospital, Ansan, Gyeonggi-do
Kyungpook National University Hospital, Daegu, Not set
Yeungnam Univ. Medical Center, Daegu, Not set
Keimyung University Dongsan Hospital, Daegu, Not set
Wonju Severance Christian Hospital, Gangwon-do, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
SMG-SNU Boramae Medical Center, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
Hospital Universiti Sains Malaysia, Kota Bharu, Kelantan
University Malaya Medical Centre, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
Hospital Selayang, Batu Caves, Not set
ID Clinic Arkadiusz Pisula, Mysłowice, Malopolskie
Spolka Lekarzy Intercor Sp. z o.o., Bydgoszcz, Not set
Clinical Medical Research Korfantego - Ambulatoryjna Opieka, Katowice, Not set
Uniwersyteckie Centrum Kliniczne im. Prof. K. Gibińskiego Śl, Katowice, Not set
Krakowskie Centrum Medyczne Sp. z o.o., Krakow, Not set
"LANDA" Katarzyna Agata Landa, Kraków, Not set
EMC Instytut Medyczny S.A., Wroclaw, Not set
Centrum Badan Klinicznych, Wroclaw, Not set
FutureMeds Sp. z o.o., Wroclaw, Not set
Unidade Local De Saude De Matosinhos E.P.E., Senhora Da Hora, Matosinhos, Matosinhos
Unidade Local De Saude De Santa Maria E.P.E., Lisboa, Not set
FDI Clinical Research, San Juan, Not set
Penza Regional Clinical Hospital named after N.N. Burdenko, Penza, Not set
National University Hospital Singapore_Tahir Building, Singapore, Not set
National University Hospital_TBD, Singapore, Not set
Singapore General Hospital, Singapore, Not set
Changi General Hospital, Singapore, Not set
Complejo Hospitalario de Pontevedra - Hospital de Montecelo, Pontevedra, Galicia
Hospital Vall d'Hebron, Barcelona, Not set
Hospital Universitario Marqués de Valdecilla, Santander, Not set
Hospital Virgen del Rocío, Sevilla, Not set
Hospital Clínico de Valladolid, Valladolid, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set
National Cheng Kung University Hospital, Tainan, Not set
National Taiwan University Hospital, Taipei, Not set
T.C. Saglık Bakanlıgı Adana Sehir Egitim ve Arastirma Hastan, Adana, Not set
Hacettepe Universitesi Tıp Fakültesi- Gastroenteroloji, Ankara, Not set
Gazi University Medical Faculty, Ankara, Not set
Bezmialem Vakif Universitesi Tip Fakultesi Hastanesi-Gastroe, Istanbul, Not set
Marmara Univ. Pendik Gastroenterology, Istanbul, Not set
Kocaeli Universitesi Tıp Fakültesi Gastroenteroloji ve Hepat, Kocaeli, Not set
Royal Devon & Exeter NHS Foundation Trust, Exeter, Not set
Conditions: Non-alcoholic Steatohepatitis
Research Study Looking at How Well Semaglutide Works in People Living With Obesity and Prediabetes
Completed
This study looks at how well a new medicine, called semaglutide, works at helping people with obesity and prediabetes.
This study will look at how much weight participants lose, and if participants can go from having blood sugar that is higher than normal (prediabetes) to having normal blood sugar.
Semaglutide is compared to a "dummy" medicine. The "dummy" medicine looks like semaglutide but has no effect on the body.
In addition to taking the medicine, participants will have talks with study... Read More
This study looks at how well a new medicine, called semaglutide, works at helping people with obesity and prediabetes.
This study will look at how much weight participants lose, and if participants can go from having blood sugar that is higher than normal (prediabetes) to having normal blood sugar.
Semaglutide is compared to a "dummy" medicine. The "dummy" medicine looks like semaglutide but has no effect on the body.
In addition to taking the medicine, participants will have talks with study staff about healthy food choices, how to be more physically active and what participants can do to lose weight.
Participants will either get semaglutide or "dummy" medicine - which treatment they get is decided by chance. Participants are 2 times as likely to get semaglutide as "dummy" medicine.
Participants will need to take 1 injection once a week. The study medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm.
The study will last for about 19 months. Participants have to take the study medicine every week for the first 12 months. The last 7 months participants will not take any medication.
Participants will have 14 clinic visits and 1 phone call with the study staff. At 9 of the clinic visits Participants will have blood samples taken. Women cannot take part if pregnant, breast-feeding or plan to become pregnant during the study period. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/12/2025
Locations: University of Calgary, Calgary, Alberta +29 locations
University of Calgary, Calgary, Alberta
C-endo Diab Endo Clin Calgery, Calgary, Alberta
Ocean West Research Clinic, Surrey, British Columbia
G.A. Research Associates Ltd., Moncton, New Brunswick
LMC ClinRsrh Inc.Brampton, Brampton, Ontario
LMC Clin Res Inc. Thornhill, Concord, Ontario
Wharton Med Clin Trials, Hamilton, Ontario
Premier Clinical Trial Research Network (PCTRN), Hamilton, Ontario
Milestone Research, London, Ontario
Toronto Sleep Institute/MedSleep, Toronto, Ontario
Diabetes Heart Research Centre, Toronto, Ontario
Centre Medical Acadie, Montreal, Quebec
LMC Clin Rsrch Inc. (Montreal), Saint-Laurent, Quebec
Centre de recherché du CHUS, Sherbrooke, Quebec
Ctr de Med Metab de Lanaudiere, Terrebonne, Quebec
Aarhus Universitetshospital Diabetes og Hormonsygdomme, Aarhus N, Not set
Hvidovre Hospital Endokrinologisk forsknings afsnit 159, Hvidovre, Not set
Obesity Research Unit, Helsinki, Not set
StudyCor, Jyväskylä, Not set
Hospital Gregorio Marañón, Madrid, Not set
Hospital Clinico San Carlos, Madrid, Not set
Hospital Infanta Luisa, Sevilla, Not set
Clifton Medical Centre, Rotherham, South Yorkshire
The Health Centre, Bradford-on-Avon, Not set
WISDEM Centre, Coventry, Not set
Claremont Medical Practice, Exmouth, Not set
GP Direct, Harrow, Not set
Guys Hospital, London, Not set
The Staploe Medical Centre, Soham, Not set
MyHealth - Strensall Health Care Centre, Strensall, Not set
Conditions: Obesity
Semaglutide and Cognition in Healthy Volunteers
Completed
Semaglutide is a glucagon-like peptide 1 receptor agonist (GLP-1RA). It is a safe medication approved for use in type-2 diabetes mellitus (T2DM) and obesity. Primarily, it works by counteracting insulin-resistance and inducing weight loss. It also acts on several other interconnected neurobiological, immunological (esp. inflammatory), endocrine-metabolic, and gut-brain axis processes that play a role in depressive symptoms. Its effects on cognition and energy are currently unknown. In this study... Read More
Semaglutide is a glucagon-like peptide 1 receptor agonist (GLP-1RA). It is a safe medication approved for use in type-2 diabetes mellitus (T2DM) and obesity. Primarily, it works by counteracting insulin-resistance and inducing weight loss. It also acts on several other interconnected neurobiological, immunological (esp. inflammatory), endocrine-metabolic, and gut-brain axis processes that play a role in depressive symptoms. Its effects on cognition and energy are currently unknown. In this study we are using semaglutide as an experimental tool to further investigate these relationships. Read Less
Gender:
ALL
Ages:
Between 21 years and 55 years
Trial Updated:
06/03/2025
Locations: Department of Psychiatry, University of Oxford, Oxford, Oxfordshire
Department of Psychiatry, University of Oxford, Oxford, Oxfordshire
Conditions: Cognitive Change
Evaluating the Effect of the STEP@STAH Semaglutide Protocol on the Physical Health Measures of Atypical Antipsychotic-Treated Patients
Recruiting
A significant number of patients who are prescribed anti-psychotic medication such as clozapine are considered as clinically obese (BMI \>35.0). While this may be associated with the appetite promoting properties of the drug, other factors including apathy and lack of physical activity and exercise can exacerbate the weight gain. For those patients who are in a secure care setting and who have restrictions on movement, this provides a particular challenge.
Therefore, a pharmacological option to... Read More
A significant number of patients who are prescribed anti-psychotic medication such as clozapine are considered as clinically obese (BMI \>35.0). While this may be associated with the appetite promoting properties of the drug, other factors including apathy and lack of physical activity and exercise can exacerbate the weight gain. For those patients who are in a secure care setting and who have restrictions on movement, this provides a particular challenge.
Therefore, a pharmacological option to assist in promoting weight loss would be an attractive option for patients who have reached levels of obesity and for whom diet and exercise alone may not be sufficient. The GLP-1 agonist class of drugs, including semaglutide (Wegovy®), have been approved for the treatment of patients as an adjunct to diet and exercise and for weight loss in adults who have a BMI of 30 kg/m² or greater (obese) or weight-related health problems. The aim of this study is to determine whether long-term treatment with Semaglutide (Wegovy®), in combination with dietary advice, exercise and psychological support, will decrease the weight gain associated with anti-psychotic treatment. Patients will be chosen for the trial according to NICE guidelines for referral to a weight management plan. In addition to the weekly Semaglutide (Wegovy®) injection, they will have regular access to dietary and exercise support as part of an overall healthy lifestyle plan which will form part of their overall care plan. They will also be provided with psychological support as a previous trial demonstrated that behavioural support was important, especially at the early stages of such therapy. The patients' progress will be monitored (weight, activity, diet) throughout the duration of the trial. The results will identify those patients who are most likely to benefit from this therapy and can be used to generate treatment guidelines." Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: St Andrew's Healthcare, Northampton, Not set
St Andrew's Healthcare, Northampton, Not set
Conditions: Obesity and Obesity-related Medical Conditions, Psychiatric Disorders
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes
Completed
The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on an empty stomach and not eat or drink anything for at least 30 minutes. The study will last for about 3.5-5 years. Participants will have up to 25 clinic visits and 1 phone ca... Read More
The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on an empty stomach and not eat or drink anything for at least 30 minutes. The study will last for about 3.5-5 years. Participants will have up to 25 clinic visits and 1 phone call with the study doctor. Women cannot be in the study if pregnant, breast-feeding or if they plan to become pregnant during the study period. Read Less
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/08/2025
Locations: Healthscan Clinical Trials,LLC., Montgomery, Alabama +473 locations
Healthscan Clinical Trials,LLC., Montgomery, Alabama
Medical Investigations, Inc., Little Rock, Arkansas
Unity Health-Searcy Medical Center, Searcy, Arkansas
B&K Medical Research Center, Fresno, California
Scripps Whittier Diabetes Inst, La Jolla, California
Diabetes & Endocrine Associates, La Mesa, California
First Valley Medical Group, Lancaster, California
Pacific Clinical Studies, Los Alamitos, California
Facey Medical Foundation, Mission Hills, California
Monterey Endocrine & Diabetes Institute, Inc, Monterey, California
Desert Oasis Hlthcr Med Group, Palm Springs, California
San Diego Family Care, San Diego, California
Lundquist Inst-Biomed Innovtn, Torrance, California
Coastal Metabolic Research Center, Ventura, California
Rocky Mount Reg VA Med-DN, Aurora, Colorado
Creekside Endocrine Associates, PC, Denver, Colorado
New West Physicians,Inc., Golden, Colorado
East Coast Medical Associates, Inc., Boca Raton, Florida
Suncoast Clin Res Port Richey, New Port Richey, Florida
AdventHealth Diab Inst, Orlando, Florida
Ellipsis Group, Alpharetta, Georgia
Physicians Research Assoc. LLC, Lawrenceville, Georgia
Endo Res Solutions Inc, Roswell, Georgia
East West Med Res Inst, Honolulu, Hawaii
Rocky Mountain Diab&Osteo Ctr, Idaho Falls, Idaho
Clinical Invest Special_Gurnee, Gurnee, Illinois
American Health Network of IN LLC_Franklin, Franklin, Indiana
American Health Network of Indiana, LLC_Greenfield, Greenfield, Indiana
Franciscan Health Michigan City, Michigan City, Indiana
American Health Network of IN LLC, Muncie, Indiana
Iowa Diab & Endo Res Center, West Des Moines, Iowa
The Research Group of Lexington LLC, Lexington, Kentucky
Robley Rex VA Medical Center, Louisville, Kentucky
L-MARC Research Center, Louisville, Kentucky
Tulane University Health Sciences Center, New Orleans, Louisiana
Ileana J Tandron APMC, Slidell, Louisiana
Northern Pines Hlth Ctr, PC, Buckley, Michigan
Methodist Phys. Clinic, Omaha, Nebraska
Univ of Nebraska Medical CTR, Omaha, Nebraska
Palm Research Center Inc-Vegas, Las Vegas, Nevada
Dartmouth-Hitchcock Med Ctr, Lebanon, New Hampshire
Southern New Hampshire Diabetes and Endocrinology, Nashua, New Hampshire
Albany Medical College - Endo, Albany, New York
Southgate Medical Group, LLP, West Seneca, New York
Great Lakes Medical Research, Westfield, New York
Mountain Diabetes & Endocrine Center, Asheville, North Carolina
Kernodle Clin Dpt-Pvt Diagnost, Burlington, North Carolina
University of North Carolina, Chapel Hill, North Carolina
PharmQuest Life Sciences LLC, Greensboro, North Carolina
Physicians East Endocrinology, Greenville, North Carolina
Eastern Nephr Assoc, PLLC, New Bern, North Carolina
Whiteville Medical Associates, Whiteville, North Carolina
Accellacare, Wilmington, North Carolina
Lillestol Research LLC, Fargo, North Dakota
Advanced Med Res Maumee, Maumee, Ohio
Your Diabetes Endocrine Nutrition Group, Inc., Mentor, Ohio
Twinsburg Family Health Center, Twinsburg, Ohio
Lynn Institute of Norman, Norman, Oklahoma
Heritage Valley Medical Group Inc, Beaver, Pennsylvania
Primary Care Research South, Inc, McMurray, Pennsylvania
Aria Endocrine Metabolic Assoc, Philadelphia, Pennsylvania
Preferred Primary Care Physicians Inc., Pittsburgh, Pennsylvania
The Diabetes Center, LLC, Murrells Inlet, South Carolina
Carolina Health Specialists, Myrtle Beach, South Carolina
Spartanburg Medical Research, Spartanburg, South Carolina
Michael L Reeves, MD, Chattanooga, Tennessee
Univ Diab & Endo Consultants, Chattanooga, Tennessee
Holston Medical Group, Kingsport, Tennessee
InvestiClin Research, Nashville, Tennessee
MidState Endocrine Associates, Nashville, Tennessee
Vanderbilt Diab Obes Clin Tri, Nashville, Tennessee
Trinity Clinical Research LLC, Tullahoma, Tennessee
Arlington Family Res. Ctr Inc, Arlington, Texas
Central Texas Clinical Research, Austin, Texas
Texas Diabetes & Endocrinology, P.A._Austin, Austin, Texas
Texas Diabetes & Endocrinology, Austin, Texas
Velocity Clinical Res-Dallas, Dallas, Texas
UT Southwestern Med Cntr, Dallas, Texas
Diabetes and Thyroid Ctr of FW, Fort Worth, Texas
PrimeCare Medical Group, Houston, Texas
Synergy Groups Medical, Houston, Texas
DCOL Ctr for Clin Res, Longview, Texas
Midland Clinical Research Center, Midland, Texas
Texas Diabetes & Endocrinology, P.A._Austin, Round Rock, Texas
Simcare Medical Research, LLC, Sugar Land, Texas
Hillcrest Family Health Center, Waco, Texas
University of Vermont Medical Center, South Burlington, Vermont
Dominion Medical Associates, Richmond, Virginia
Selma Medical Associates, Winchester, Virginia
Clinical Inv Spec, Inc.Kenosha, Kenosha, Wisconsin
Internal medicine department, Algiers, Not set
endocrino-diabetology department, Hospital IBN BADIS., Constantine, Not set
Internal Medecine department CHU Ibn Badis, Constantine, Not set
EHU 1st November 1954, Oran, Not set
Internal Medicine departement CHU Oran, Oran, Not set
Department of internal of medicine, CHU Setif, Setif, Not set
Centro Médico CIMEL, Lanus Este, Buenos Aires
DIM Clinica Privada, Buenos Aires, Not set
Centro Medico Lebensohn, Buenos Aires, Not set
Hospital Italiano, Buenos Aires, Not set
Centro de Investigaciones Metabólicas, Capital Federal, Not set
Centro Diabetologico Cordoba Dr. Waitman, Cordoba, Not set
Centro médico privado Cemaic, Córdoba, Not set
Instituto Médico DAMIC, Córdoba, Not set
Centro Médico Privado San Vicente Diabetes, Córdoba, Not set
Centro Médico CIMEL, Lanus Este, Not set
Instituto de Investigaciones Clinicas, Mar del Plata, Not set
Sanatorio Britanico S.A., Rosario, Santa Fe, Not set
Univ.-Klinik für Innere Medizin, Graz, Not set
Medizinische Universität Innsbruck, Innsbruck, Not set
Fließer-Görzer [Ordination], Saint Stefan, Not set
Klinik Hietzing, Wien, Not set
Klinik Ottakring, Wien, Not set
Imeldaziekenhuis - Bonheiden - Department of Endocrinology, Bonheiden, Not set
UZ Antwerpen - UZA - Department of Endocrinology, Edegem, Not set
UZA - UZ Antwerpen - Department of Endocrinology, Edegem, Not set
UZ Gent - Endocrinologie - Diabetologie, Gent, Not set
AZ Groeninge - Kortrijk - Centrum Endo - Diabetologie, Kortrijk, Not set
UZ Leuven - Endocrinology, Leuven, Not set
AZ Delta - Roeselare - Diabeteskliniek, Roeselare, Not set
AZ Delta - Roeselare, Roeselare, Not set
Hospital do Coração do Brasil, Brasilia, Distrito Federal
Cline Research Center, Curitiba, Parana
Quanta Diagnóstico Nuclear / Medicina Nuclear Alto da XV, Curitiba, Parana
Hospital São Vicente de Paulo, Passo Fundo, Rio Grande Do Sul
Instituto de Pesquisa Clínica de Campinas, Campinas, Sao Paulo
i9 Pesquisas Clínicas, Campinas, Sao Paulo
Instituto de Pesquisa Clinica (IPEC), São Paulo, Sao Paulo
CPQuali Pesquisa Clínica Ltda, São Paulo, Sao Paulo
CPCLIN - Centro de Pesquisas Clínicas, São Paulo, Sao Paulo
C-endo Diab Endo Clin Calgery, Calgary, Alberta
Vancouver General Hospital_Vancouver_0, Vancouver, British Columbia
Nova Scotia Hlth Halifax, Halifax, Nova Scotia
LMC Diabetes & Endocrinology (Barrie), Barrie, Ontario
LMC ClinRsrh Inc.Brampton, Brampton, Ontario
Aggarwal and Assoc Ltd., Brampton, Ontario
LMC Clinical Res Thornhill, Concord, Ontario
Premier Clinical Trial Research Network (PCTRN), Hamilton, Ontario
McMaster University, Hamilton, Ontario
Bluewater Clin Res Group, Inc., Sarnia, Ontario
Bluewater Clin Res Group,Inc, Sarnia, Ontario
St. Michael's Hospital, Toronto, Ontario
UHN-Toronto General Hospital, Toronto, Ontario
Diabetes Heart Research Centre, Toronto, Ontario
Manna Research Mirabel, Mirabel, Quebec
Applied Med Inf Res, Montreal, Quebec
CHU de Quebec-Universite Laval, Quebec, Not set
Peking University People's Hospital-Endocrinology, Beijing, Beijing
Cangzhou People's Hospital-Endocrinology, Cangzhou, Hebei
Cangzhou People's Hospital, Cangzhou, Hebei
Changzhou No.2 People's Hospital, Yanghu Branch, Changzhou, Jiangsu
The Affiliated Hospital of Jiangsu University-Endocrinology, Zhenjiang, Jiangsu
The Affiliated Hospital of Jiangsu University_Zhenjiang, Zhenjiang, Jiangsu
Jinan Central Hospital, Ji'nan, Shandong
Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong
Shanghai Fifth People's Hospital-Endocrinology, Shanghai, Shanghai
Clinica de la Costa, Barranquilla, Atlántico
Fundación Hospital Universidad del Norte, Soledad, Barranquilla
Unidad de Estudios Clínicos de la Fundación Cardiovascular de Colombia, Bucaramanga-piedecuesta, Valle Del Menzuli - Santander, Santander
Fundacion Valle del Lili, Cali, Valle Del Cauca
Clinica de la Costa, Barranquilla, Not set
Fundación Centro de Obesidad y Metabolismo COMETA, Pasto, Not set
Poliklinika Solmed, Zagreb, Grad Zagreb
Specijalna bolnica Krapinske Toplice - Endokrinologija, Krapinske Toplice, Not set
Klinicki bolnicki centar Osijek, Osijek, Not set
Opca bolnica Pula, Pula, Not set
KBC Rijeka, Zavod za endokrinologiju, Rijeka, Not set
KBC Split / Krizine / Dijabetes, Split, Not set
Opca bolnica Varazdin, Varazdin, Not set
Opca bolnica Zadar, Zadar, Not set
KB Merkur - Sveucilisna klinika Vuk Vrhovac, Zagreb, Not set
KB Dubrava, Zavod za endokrinologiju i dijabetes, Zagreb, Not set
University Hospital U sv. Anny, Brno, Not set
Intendia klinika, Chrudim, Not set
FN Hradec Kralove, Hradec Kralove, Not set
Diabetologicka a Interni Ambulance MUDr. Jan Vrkoc s.r.o., Moravska Ostrava, Not set
Ambulance DIA - INTERNA s.r.o., Ostrava, Not set
Diabetologicka ambulance Plzen, Plzen, Not set
MUDr. Jitka Zemanova diabetologie a interna, Plzeň - Východní Předměstí, Not set
DIALINE s.r.o., Plzeň 3, Not set
Institut klinicke a experimentalni mediciny_Praha, Praha, Not set
Aarhus Universitetshospital, Steno Diabetes Center Aarhus, Aarhus N, Not set
Hillerød Endokrinologisk amb. H0652, Hillerød, Not set
Bispebjerg Hospital, IC-Forskning, København, Not set
Slagelse Sygehus Ambulatorium for hjertesygdomme, Slagelse, Not set
Svendborg Sygehus, Svendborg, Not set
Centre Hospitalier Universitaire de Besancon-Hopital Jean Minjoz, Besançon cedex, Not set
Centre Hospitalier Universitaire de Dijon-Hopital Le Bocage, DIJON cedex, Not set
Les Hopitaux de Chartres-Hopital Louis Pasteur, Le Coudray, Not set
Assistance Publique Hopitaux de Marseille-Hopital de La Conception, Marseille, Not set
Centre Hospitalier de Narbonne, Narbonne, Not set
Ap-Hp-Hopital Bichat-Claude Bernard-1, Paris, Not set
Centre Hospitalier Universitaire de Bordeaux-Hopital Haut Leveque-2, Pessac, Not set
Les Hopitaux Universitaires de Strasbourg-Hopital de Hautepierre-1, Strasbourg, Not set
MVZ "Am Felsenkeller" (Dresden), Dresden, Not set
Uniklinik TU Dresden Med. Klinik III, Dresden, Not set
Praxis Dr. med. M. Esser, Essen, Not set
Zentrum für klinische Forschung, Dr. med. Lüdemann, Falkensee, Not set
Diabetologische Schwerpunktpraxis Harburg - Dr. med.Paschen, Hamburg, Hamburg, Not set
Diabetes Zentrum Wandsbek Berufsausuebungsgemeinschaft GbR, Hamburg, Not set
Praxisgemeinschaft Jerichow, Jerichow, Not set
Diabetologische Gemeinschaftspraxis Dr. Staudenmeyer und Dr. Schiwietz, Lingen, Not set
Die Praxis am Ludwigsplatz, Ludwigshafen, Not set
Institut für Diabetesforschung GmbH Münster - Dr. med. Rose, Münster, Not set
RED-Institut für medizinische Forschung und Fortbildung GmbH, Oldenburg in Holstein, Not set
Praxis Dr. med. Wenzl-Bauer, Rehlingen-Siersburg, Not set
Marienhospital Stuttgart - Innere Medizin 1, Stuttgart, Not set
Forschungszentrum Ruhr KliFoCenter GmbH, Dr. med. Kahrmann, Witten, Not set
Prince of Wales Hospital, Shatin, New Territories, Not set
Osmania General Hospital, Hyderabad, A.p.
Sunshine Hospital, Hyderabad, Andhra Pradesh
Care Outpatient Centre, Hyderabad, Andhra Pradesh
Ramdev Rao Hospital, Hyderabad, Andhra Pradesh
Apollo Excelcare Hospital, Guwahati, Guwahati, Assam
Apollo Excelcare Hospital, Guwahati, Assam
HCG Hospitals, Ahmedabad, Gujarat
Dr. Jivraj Mehta Health Foundation, Ahmedabad, Gujarat
PGIMS Rohtak, Rohtak, Haryana
Ramaiah Memorial Hospital, Bangalore, Karnataka
Lifecare Hospital and Research Centre, Bangalore, Karnataka
Calicut Medical College, Kozhikode, Kerala
TOTALL Diabetes Hormone Institute, Indore, Madhya Pradesh
P D Hinduja National Hospital and Medical Research Centre, Mumbai, Maharashtra
BYL Nair Hospital and T N Medical College Department of endo, Mumbai, Maharashtra
P D Hinduja National Hospital and Medical Research Centre, Mumbai, Maharashtra
BSES MG hospital, Mumbai, Maharashtra
Fortis Hospital Mulund, Mumbai, Maharashtra
Fortis Hospital, Mulund, Mumbai, Mumbai, Maharashtra
chelleram Diabetes Institute, Pune, Maharashtra
Inamdar Multispeciality Hospital, Pune, Maharashtra
All India Institute of Medical Sciences, New Dehli, New Delhi
Kanungo Institute of Diabetes Specialities Pvt Ltd, Bhubaneswar, Orissa
Dayanand Medical College & Hospital, Ludhiana, Punjab
Christian Medical College and Hospital, Ludhiana, Punjab
Fortis Heart Institute and Multispeciality Hospital, Mohali, Punjab
Diabetes, Thyroid and Endocrine Centre, Jaipur, Rajasthan
Madras Diabetes Research Foundation, Chennai, Tamil Nadu
Kg Hospital and Post Graduate Medical Institute, Coimbatore, Tamil Nadu
Christian Medical College Hospital, Vellore, Ranipet, Tamil Nadu
Christian Medical College Hospital, Vellore, Vellore, Tamil Nadu
Osmania General Hospital, Hyderabad, Telangana
Ramdev Rao Hospital, Hyderabad, Telangana
Gandhi Hospital & Medical college, Hyderabad, Telengana
SSKM, Kolkata, West Bengal
Apollo Gleneagles Hospital, Kolkata, West Bengal
Apollo Multispeciality Hospital, Kolkata, Kolkata, West Bengal
Lady Hardinge Medical College, New Delhi, Not set
Jothydev's Diabetes & Research Center, Thriruvananthapuram, Not set
Diabetes and obesity center of excellence, Rambam MC, Haifa, Not set
Diabetes Unit Hadassah Ein Karem MC, Jerusalem, Not set
Endocrinology & Diabetes Clinic Clalit Jerusalem, Jerusalem, Not set
Clinical Research Unit Meir Medical Center, Kfar Saba, Not set
Institute of Diabetes, Western Galilee MC Nahariya, Nahariya, Not set
Rabin MC Beilinson Campus Endo, Petah-Tikva, Not set
Endrocrinolgy Clinic - Sheba Medical Center, Tel Hashomer, Not set
Sheba Medica Center - Clinical Research Unit, Tel Hashomer, Not set
Institute of Endocrinology, metabolism and hypertension, Tel-Aviv, Not set
A.O.U. Consorziale Policlinico di Bari, Bari, BA
Azienda Ospedaliero-Universitaria Renato Dulbecco, Catanzaro, Cz
Ospedale Civile Campo di Marte, Lucca, LU
Istituto Scientifico San Raffaele, Milano, MI
Policlinico Umberto I Seconda Clinica Medica, Roma, RM
Azienda Ospedaliera di Perugia;Ospedale S. Maria della Misericordia, Perugia, Umbria
Università degli studi G. D'Annunzio Chieti Pescara - CAST, Chieti Scalo, Not set
Centro Cardiologico Monzino. Istituto di Ricovero e Cura, Milano, Not set
Università Federico II Dip. di Med. Clinica e Chirurgia Ed 1, Napoli, Not set
Azienda Ospedaliera di Padova Malatt.Metab, Padova, Not set
Dip. di Medicina Interna Policlinico Universitario Palermo, Palermo, Not set
Policlinico Universitario Paolo Giaccone, Palermo, Not set
Jinnouchi Hospital, Kumamoto-shi, Kumamoto, Japan
Heiwadai Hospital, Miyazaki-shi, Miyazaki
The University of Tokyo Hospital, Diabetes and Metabolic, Bunkyo-ku, Tokyo, Not set
New Tokyo Heart Clinic_Matsudo-shi, Chiba,, Chiba, Not set
Ehime Prefectural Central Hospital, Ehime, Not set
Fukui Prefectural Hospital, Fukui, Not set
Fukuoka Tokushukai Hospital, Fukuoka, Not set
Naka Kinen Clinic, Ibaraki, Not set
Kyoto University Hospital, Kyoto-shi, Kyoto, Not set
Uji Tokushukai Medical Center, Kyoto, Not set
Shinden Higashi Clinic_Miyagi, Miyagi, Not set
Shinshu University Hospital, Nagano, Not set
Saiseikai Suita Hospital, Osaka, Not set
Osaka University Hospital_Osaka, Osaka, Not set
Takatsuki Red Cross Hospital, Osaka, Not set
Nozaki Tokushukai Hospital, Osaka, Not set
Saga University Hospital, Department of Cardiology, Saga-shi, Saga, Not set
Hanaoka Seishu Memorial Hospital, Sapporo-shi, Hokkaido, Not set
Kagawa Prefectural Central Hospital, Cardiovascular Medicine, Takamatsu-shi, Kagawa, Not set
Oyama East Clinic, Tochigi, Not set
Tokorozawa Heart Center, Tokorozawa-shi, Saitama, Not set
Tokyo-Eki Center-building Clinic, Tokyo, Not set
Juntendo University Hospital_Tokyo, Tokyo, Not set
Juntendo University Hospital, Tokyo, Not set
Sugawara Clinic, Tokyo, Not set
Minamino Cardiovascular Hospital, Tokyo, Not set
Tokyo Nishi Tokushukai Hospital, Tokyo, Not set
Seoul National University Bundang Hospital, Gyeonggi-do, Not set
Hanyang University GURI Hospital, Gyeonggi-do, Not set
Korea University Anam Hospital, Seoul, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Asan Medical Center, Seoul, Not set
Seoul Saint Mary's Hospital, Seoul, Not set
Nowon Eulji Medical Center, Eulji University, Seoul, Not set
Hospital Sultanah Bahiyah, Alor Setar, Kedah
Hospital Raja Perempuan Zainab II, Kota Bharu, Kelantan
Hospital Universiti Sains Malaysia_Kota Bharu, Kelantan, Kota Bharu, Kelantan
Sarawak Heart Centre, Kota Samarahan, Sarawak
University Technology MARA (UiTM) - Puncak Alam, Sungai Buloh, Selangor
University Technology MARA (UiTM) - Sg Buloh, Sungai Buloh, Selangor
University Malaya Medical Centre, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
Hospital Putrajaya, Putrajaya, Wilayah Persekutuan Putrajaya
Hospital Sultanah Bahiyah, Alor Setar, Not set
Sarawak General Hospital, Kuching, Not set
Hospital Miri, Sarawak, Not set
Hospital Tuanku Jaafar, Seremban, Not set
Hospital Putrajaya, Wilayah Persekutuan Putrajaya, Not set
Inst. Jaliscience de Investigacion en Diabetes y Obesidad SC, Guadalajara, Jalisco
Arechavaleta Granell María del Rosario, Guadalajara, Jalisco
Centro de Atención Integral al Paciente con Diabetes, Tlalpan, México, D.F.
Cardiolink Clin Trials S.C., Monterrey, Nuevo Leon
Internal Medicine Clin Trials, Monterrey, Nuevo León
Unidad Medica para la Salud Integral (UMSI), San Nicolas de los Garza, Nuevo León
Investigación Médica Sonora S.C., Hermosillo, Sonora
Medical Care and Research S. A de C.V, Merida, Yucatan
Centro de Desarrollo Biomédico S.C.P., Mérida, Yucatan
EME Red Hospitalaria, Mérida, Yucatán
Centro de Investigación Cardiometabólica de Aguascalientes, Aguascalientes, Not set
Meander Medisch Centrum, Amersfoort, Not set
Amsterdam UMC Lokatie VUMC, Amsterdam, Not set
Gelre Ziekenhuizen Apeldoorn, Apeldoorn, Not set
Reinier de Graaf Gasthuis, Delft, Not set
Maxima Medisch Centrum, Eindhoven, Not set
Martini Ziekenhuis, Groningen, Not set
Bethesda Diabetes Research Center en Bethesda ziekenhuis, Hoogeveen, Not set
Maastricht Universitair Medisch Centrum, Maastricht, Not set
Radboudumc, Nijmegen, Not set
Universitair Medisch Centrum Utrecht, Utrecht, Not set
Clinic of Diabetes Cluj, Cluj Napoca, Cluj
Spitalul Judetean de Urgenta Targoviste, Targoviste, Dambovita
Spitalul Clinic Judetean de Urgenta Targu Mures, Targu Mures, Mures
Sc Mediab Srl, Tirgu Mures, Mures
Novus Medical Clinica SRL, Ploiesti, Prahova
CMI Dr. Busegeanu Mihaela Magdalena, Ploiesti, Prahova
CMI Dr. Pletea Noemi SRL, Bacau, Not set
Diabet Med SRL, Bucharest, Not set
Clinical Emergency Sf. Apostol Andrei Hospital, Galati, Not set
SC Gensan SRL, Policlinica ASTRA, Sibiu, Not set
Tumen State Medical University, Tumen, Russia
City Hospital #5, Barnaul, Not set
Kazan Federal University, Kazan, Not set
LLC "Clinic of Aesthetic Medicine & Laser Technologies", Kazan, Not set
SAHI Kuzbass Hospital(former Regional clinical hospital), Kemerovo, Not set
Friendship University of Russia, Moscow, Not set
Setchenov First Moscow State Medical University, Moscow, Not set
State Novosibirsk regional clinical hospital, Novosibirsk, Not set
Limited Law Company "Healthy Family" Medicine Center", Novosibirsk, Not set
Penza Regional Clinical Hospital named after N.N. Burdenko, Penza, Not set
Aurora MedFort LLC, Saint Petersburg, Not set
SPb SBHI City Outpatient clinic #37, Saint-Petersburg, Not set
City Consultative & Diagnostic Centre #1, Saint-Petersburg, Not set
Consultative & Diagnostic Center with a Outpatient Hospital, Saint-Petersburg, Not set
Regional clinical cardiology dispensary, Saratov, Not set
Saratov regional clinical hospital, Saratov, Not set
SPb SBHI City Multifield Hospital #2, St. Petersburg, Not set
Siberian State Medical University, Tomsk, Not set
Ulianovsk Regional Clinical Hospital, Ulianovsk, Not set
Yaroslavl Regional Hospital, Yaroslavl, Not set
Polyclinic #2 in Yoshkar-Ola, Yoshkar-Ola, Not set
Clin. Centre Vojvodina, Clin. endocr., diab. and met. dis., Novi Sad, Vojvodina
CHC Zvezdara, Clinical department for endocrinology, Belgrade, Not set
Endocrinology, Diabetes and Metabolism Diseases Clinic, Belgrade, Not set
Military Medical Academy, Belgrade, Not set
Clinical Centre Kragujevac, Internal Diseases Clinic, Endocrinology department, Kragujevac, Not set
Clinical Centre Nis, Endocrinology, Diabetes and Metabolism, Nis, Not set
Policlinic for diabetes, Zajecar, Not set
Metabolicke Centrum MUDr. Katariny Raslovej s.r.o., Bratislava, Not set
MediTask, s.r.o, Bratislava, Not set
Nemocnica akademika L. Derera, UNB, Bratislava, Not set
HUMAN-CARE s.r.o., Kosice, Not set
CARDIO D&R, s.r.o., Kosice, Not set
Nemocnica Krompachy spol. s r.o Diabetol. amb. MD Gmitrov, Krompachy, Not set
Diabetologicka ambulancia MUDr. Katarina Plevova, s.r.o., Nitra, Not set
DENTAVIA s.r.o., Poprad, Not set
MUDr. Jan Culak, s.r.o., Prievidza, Not set
Kardiologicka a interna ambulancia, Rimavska Sobota, Not set
Tatratrial s.r.o., Roznava, Not set
IRIDIA s.r.o., Vrutky, Not set
Diabetes Care Centre & CDE Centre, Benoni, Gauteng
Peermed Clinical Trial Centre, Johannesburg, Gauteng
Soweto Clinical Trial Centre, Johannesburg, Gauteng
Deepak Lakha, Johannesburg, Gauteng
Hemant Makan, Johannesburg, Gauteng
Deepak Lakha, Johannesburg, Gauteng
Centre for Diabetes, Johannesburg, Gauteng
Dr Seeber, Pretoria, Gauteng
Prof P. Joshi, Pretoria, Gauteng
Dr H Bacus, Berea, KwaZulu-Natal
Dr A Amod, Durban, KwaZulu-Natal
Dr T Padayachee, Durban, KwaZulu-Natal
Dr Pillay's Rooms, Durban, KwaZulu-Natal
Diabetes Clinical Trials Unit, Cape Town, Western Cape
UCT Clinical Research Centre, Cape Town, Western Cape
Hospital Fundación Alcorcón, Alcorcón, Madrid
Hospital Comarcal de Antequera, Antequera, Not set
Hospital del Mar, Barcelona, Not set
Hospital Público da Mariña, Burela, Not set
Hospital Reina Sofia, Córdoba, Not set
Complejo Hospitalario Universitario A Coruña, La Coruña, Not set
Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Not set
Hospital Ribera Polusa, Lugo, Not set
Hospital Clínico Virgen de la Victoria, Málaga, Not set
Hospital Quirón, Pozuelo de Alarcon, Not set
Hospital Virgen del Camino - Sanlúcar de Barrameda, Sanlúcar de Barrameda, Not set
Hospital Universitario Marqués de Valdecilla, Santander, Not set
Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Not set
Hospital Virgen de la Macarena, Sevilla, Not set
Changhua Christian Hospital, Changhua City, Not set
Chung Shan Medical University Hospital, Taichung City, Not set
Chang Gung Medical Foundation - Linkou Branch, Taoyuan city, Not set
Siriraj Hospital_Bangkoknoi, Bangkok, Bangkoknoi, Bangkok, Bangkok
Songklanagarind Hospital, Songkla, Had-Yai
Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Mueang Chiang Mai
King Chulalongkorn Memorial Hospital_Bangkok, Bangkok, Not set
Police General Hospital, Bangkok, Not set
Phramongkutklao Hospital, Bangkok, Not set
Rajavithi Hospital, Bangkok, Not set
Ramathibodi Hospital-Cardiovascular metabolic Center, Bangkok, Not set
Siriraj Hospital_Bangkok_1, Bangkok, Not set
Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Not set
T.C. Saglık Bakanlıgı Adana Sehir Egitim ve Arastirma Hastan, Adana, Not set
Gulhane Egitim Arastirma Hastanesi, Ankara, Not set
Bursa Il Saglik Mudurlugu Yuksek Ihtısas Egitim ve Arastirma Hastanesi, Bursa, Not set
T.C. Saglik Bakanligi Bursa Il Saglik Mudurlugu Yuksek Ihtıs, Bursa, Not set
Ataturk Universitesi Tip Fakultesi, Erzurum, Not set
Eskisehir Osmangazi University School of Medicine, Eskisehir, Not set
Hatay Mustafa Kemal Universitesi Saglik Uygulama ve Arastirm, Hatay, Not set
Haseki Egitim ve Arastirma Hastanesi_ISTANBUL, Istanbul, Not set
Kanuni Sultan Suleyman Egitim ve Arastirma Hastanesi, Istanbul, Not set
T.C SB Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Not set
Dokuz Eylul University Medical Faculty, Izmir, Not set
Erciyes Universitesi Tip Fakultesi, Kayseri, Not set
Sivas Cumhuriyet Univesity Endocrinology Department, Sivas, Not set
Karadeniz University School of Medicine-Adult Endocrinology, Trabzon, Not set
Cherkasy Regional Hospital of Cherkasy Reg. Council, Cherkasy, Not set
RMI "Chernivtsi Regional Endocrinology Centre", Chernivtsi, Not set
CI Dnipropetrovsk Regional Hospital, Dnipro, Not set
Clinical Hosp on the railway line №2 branch PHC JSC Ukrzaliz, Kyiv, Not set
SRI "Centre of Innovative Medical Technologies of the NASU", Kyiv, Not set
Lviv Regional Endocrinology Diagnostic and Treatment Centre, Lviv, Not set
Odesa Regional Clinical Hospital, Odesa, Not set
CI "1st City Clinical Hospital of Poltava City Council", Poltava, Not set
Transcarpathian Regional Clinical Hospital of A. Novak, Uzhhorod, Not set
Zhytomir Regional Clinical Hospital, Zhytomyr, Not set
Crouch Oak Family Practice, Addlestone, Surrey
Aberdeen Royal Infirmary, Aberdeen, Not set
Royal Victoria Hospital, Belfast, Not set
The Health Centre, Bradford-on-Avon, Not set
Southmead Hospital, Bristol, Not set
Addenbrooke's Hospital_Cambridge, Cambridge, Not set
Hathaway Surgery, Chippenham, Not set
WISDEM Centre, Coventry, Not set
Western General Hospital, Edinburgh, Not set
Glasgow Clinical Research Facility, Glasgow, Not set
Queen Elizabeth University Hospital, Glasgow, Not set
Harrogate District Hospital, Harrogate, Not set
Burbage Surgery, Hinckley, Not set
Hull Royal Infirmary, Hull, Not set
Royal Free - Diabetes, London, Not set
North Manchester General Hospital - Diabetes Centre, Manchester, Not set
The Norfolk and Norwich University Hospital, Norfolk, Not set
University Dept of Medicine, Derriford Hospital, Plymouth, Plymouth, Not set
East Surrey Hospital, Redhill, Not set
The Staploe Medical Centre, Soham, Not set
Joint Clinical Research Facility - Swansea, Swansea, Not set
Conditions: Diabetes Mellitus, Type 2
A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease
Completed
The researchers are doing this study to see if semaglutide can slow down the growth and worsening of chronic kidney disease in people with type 2 diabetes. Participants will get semaglutide (active medicine) or placebo ('dummy medicine'). This is known as participants' study medicine - which treatment participants get is decided by chance. Semaglutide is a medicine, doctors can prescribe in some countries for the treatment of type 2 diabetes. Participants will get the study medicine in a pen. Pa... Read More
The researchers are doing this study to see if semaglutide can slow down the growth and worsening of chronic kidney disease in people with type 2 diabetes. Participants will get semaglutide (active medicine) or placebo ('dummy medicine'). This is known as participants' study medicine - which treatment participants get is decided by chance. Semaglutide is a medicine, doctors can prescribe in some countries for the treatment of type 2 diabetes. Participants will get the study medicine in a pen. Participants will use the pen to inject the medicine in a skin fold once a week. The study will close when there is enough information collected to show clear result of the study. The total time participants will be in this study is about 3 to 5 years, but it could be longer. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/13/2025
Locations: Dr. Terence Hart, Tuscumbia, Alabama +412 locations
Dr. Terence Hart, Tuscumbia, Alabama
California Inst Of Renal Res, Chula Vista, California
John Muir Physician Network, Concord, California
John Muir Physicians Network, Concord, California
Valley Research, Fresno, California
California Institute of Renal Research, La Mesa, California
First Valley Med Grp Lancaster, Lancaster, California
Clinical Trials Research_Sacramento, Lincoln, California
VA Loma Linda Hlthcr Sys, Loma Linda, California
Long Beach Center For Clinical Research, Long Beach, California
VA Long Beach Healthcare System, Long Beach, California
Academic Medical Research Institute, Los Angeles, California
Valley Renal Medical Group Research, Northridge, California
Desert Oasis Hlthcr Med Group, Palm Springs, California
Saviers Medical Group, Port Hueneme, California
Inland Empire Clin Trials LLC, Rialto, California
Sierra Clinical Research, Roseville, California
California Research Foundation, San Diego, California
N America Res Inst - San Dimas, San Dimas, California
NorCal Endocrinology and Internal Medicine, San Ramon, California
Lundquist Inst-Biomed Innovtn, Torrance, California
San Fernando Valley Hlth Inst, West Hills, California
Rocky Mount Reg VA Med-DN, Aurora, Colorado
Creekside Endocrine Associates, PC, Denver, Colorado
BayCare Medical Group - Endocrinology, Clearwater, Florida
Horizon Rs Grp, Coral Gbls, Coral Gables, Florida
Cesar Figueroa M.D. P.A., Delray Beach, Florida
Northeast Research Institute, Fleming Island, Florida
Palmetto Medical General Plaza, Hialeah, Florida
Encore Medical Research LLC, Hollywood, Florida
Homestead Associates In Research, Homestead, Florida
San Marcus Res Clin Miami Lakes, Miami Lakes, Florida
Floridian Clinical Research, LLC, Miami Lakes, Florida
Life Spring Research, Miami, Florida
Oceane 7 Medical & Research Center, Inc., Miami, Florida
International Physicians Research, Miami, Florida
South Broward Research LLC, Miramar, Florida
Suncoast Clinical Research, Inc., New Port Richey, Florida
Hanson Clinical Research Center, Port Charlotte, Florida
Northeast Research Institute, Saint Augustine, Florida
Cardiovascular Ctr of Sarasota, Sarasota, Florida
Clinical Research of Cent FL, Winter Haven, Florida
Ellipsis Group, Alpharetta, Georgia
Southeastern Clinical Research Institute, LLC, Augusta, Georgia
Endocrine Research Solutions, Roswell, Georgia
Solaris Clinical Research, Meridian, Idaho
Saltzer Medical Group Research, Nampa, Idaho
Apex Medical Research Inc, Chicago, Illinois
Clinical Invest Special_Gurnee, Gurnee, Illinois
North Suburban Nephrology LLC, Gurnee, Illinois
Endeavor Health, Skokie, Illinois
Velocity Clin. Res Valparaiso, Valparaiso, Indiana
West Broadway Clinic, Council Bluffs, Iowa
Four Rivers Clinical Research Inc, Paducah, Kentucky
Metropolitan Cardiovascular Consultants, LLC, Beltsville, Maryland
Brigham & Women's Hospital, Boston, Massachusetts
Northern Pines Hlth Ctr, PC, Buckley, Michigan
Aa Mrc Llc, Flint, Michigan
Elite Research Center, Flint, Michigan
Mayo Clinic, Rochester, Minnesota
Clinical Research Consultants, LLC, Kansas City, Missouri
Washington University_St. Louis_0, Saint Louis, Missouri
Univ of Nebraska Medical CTR, Omaha, Nebraska
Renal Medicine Associates, Albuquerque, New Mexico
Albany Medical College - Endo, Albany, New York
NYU Langone Neph Associates, Mineola, New York
NYU Nephrology Associates, New York, New York
Southgate Medical Group, LLP, West Seneca, New York
UNC Diabetes Care Center_Chapel Hill, Chapel Hill, North Carolina
Carteret Medical Group, Morehead City, North Carolina
Burke Primary Care, Morganton, North Carolina
Eastern Nephr Assoc, PLLC, New Bern, North Carolina
Whiteville Medical Associates, Whiteville, North Carolina
Accellacare, Wilmington, North Carolina
Brookview Hills Research Associates, LLC, Winston-Salem, North Carolina
Cincinnati Veterans Affairs Medical Center, Cincinnati, Ohio
Advanced Med Res Maumee, Maumee, Ohio
Alliance for Multispec Res, Norman, Oklahoma
Heritage Valley Medical Group Inc, Beaver, Pennsylvania
Lycoming Internal Medicine, Inc., Jersey Shore, Pennsylvania
Northeast Endocrine Metabolic Associates, Philadelphia, Pennsylvania
Main Street Physician's Care, Little River, South Carolina
The Diabetes Center, LLC, Murrells Inlet, South Carolina
Family Medicine of SayeBrook LLC, Myrtle Beach, South Carolina
SC Nephrology and Hypertension, Orangeburg, South Carolina
AM Diabetes And Endocrinology Center, Bartlett, Tennessee
Univ Diab & Endo Consultants, Chattanooga, Tennessee
Vanderbilt Medical Center_Nashville, Nashville, Tennessee
Central Texas Clinical Research, Austin, Texas
Texas Diabetes & Endocrinology, P.A._Austin, Austin, Texas
Research Management, Inc, Austin, Texas
Osvaldo A. Brusco MD PA, Corpus Christi, Texas
Baylor Jack and Jane Hamilton, Dallas, Texas
Research Institute Of Dallas, Dallas, Texas
UT Southwestern Med Cntr, Dallas, Texas
MedResearch Inc, El Paso, Texas
Academy of Diabetes, T&E, El Paso, Texas
Juno Research, LLC_Houston, Houston, Texas
Juno Research, LLC_Houston, Houston, Texas
Southwest Clinical Trials, Houston, Texas
Southwest Houston Research Ltd, Houston, Texas
Carlos Arauz-Pacheco Md, Pa, Rockwall, Texas
Univ Of Texas Hlth Science Cntr, San Antonio, Texas
Sun Research Institute, San Antonio, Texas
Briggs Clinical Research, LLC, San Antonio, Texas
VIP Trials, San Antonio, Texas
NE Clin Res of San Antonio, San Antonio, Texas
Simcare Medical Research, LLC, Sugar Land, Texas
University of Utah School of Medicine, Salt Lake City, Utah
University of Vermont Medical Center, South Burlington, Vermont
York Clinical Research LLC, Norfolk, Virginia
McGuire VA Medical Center, Richmond, Virginia
VA Medical Center_Salem, Salem, Virginia
Amherst Family Practice P.C., Winchester, Virginia
Capital Clin Res Ctr,LLC, Olympia, Washington
MultiCare Inst for Res & Innov, Spokane, Washington
Universal Research Group, Tacoma, Washington
Centro de Estudios Renales e Hipertensión Arterial, Villa Dominico, Buenos Aires
Centro Diabetológico y Nuticional Dr Alejandro Chertkoff, Buenos Aires, Not set
Centro Medico Dra. Laura Maffei e Investigacion Clínica Apli, Buenos Aires, Not set
FEPREVA, Caba, Not set
Centro de Investigación Clínica, Caba, Not set
Glenny Corp. S.A, Caba, Not set
Medical Center of Diabetes and Nutrition, Caba, Not set
Gosford Renal Research, Gosford, New South Wales
Royal North Shore Hospital, St Leonards, New South Wales
Westmead Hospital_Northmead, Westmead, New South Wales
Core Research Centre, Milton, Queensland
Monash Health Nephrology, Clayton, Victoria
St Vincent's Hospital_Fitzroy_0, Fitzroy, Victoria
Monash University Clinical Trial Centre, Melbourne, Victoria
The Royal Melbourne Hospital, Parkville, Victoria
Imeldaziekenhuis - Bonheiden - Department of Endocrinology, Bonheiden, Not set
Universitair Ziekenhuis Brussel - Diabeteskliniek, Brussel, Not set
UZ Brussel - Universitair Ziekenhuis Brussel, Brussel, Not set
Cliniques Universitaires Saint-Luc - Serv Endocrinologie - Diabétologie, Bruxelles, Not set
UZA - UZ Antwerpen - Department of Endocrinology, Edegem, Not set
UZ Gent - Endocrinologie - Diabetologie, Gent, Not set
UZ Leuven - Endocrinology, Leuven, Not set
Centre hospitalier universitaire de Liège (CHU de Liège), Liège, Not set
AZ Delta - Roeselare, Roeselare, Not set
Instituto de Ensino e Pesquisa Clínica do Ceará Ltda, Fortaleza, Ceara
Instituto Pró-Renal Brasil, Curitiba, Parana
Núcleo de Pesquisa Clínica do Rio Grande do Sul Ltda., Porto Alegre, Rio Grande Do Sul
Hospital e Maternidade Dr. Christovão da Gama S.A., Santo André, Sao Paulo
Instituto de Pesquisa Clinica (IPEC), São Paulo, Sao Paulo
CPQuali Pesquisa Clínica Ltda, São Paulo, Sao Paulo
CPCLIN - Centro de Pesquisas Clínicas, São Paulo, Sao Paulo
Centro Médico Hospital da Bahia, Bahia, Not set
Medical centre "Zdrave 1" OOD, Kozloduy, Not set
UMHAT "Kaspela", Depart. Endocrinology and Metab. Diseases, Plovdiv, Not set
MHAT "Dr. Ivan Seliminski"-Sliven, Sliven, Not set
"Nader Yabrudi - ASMPVBE Individual practice", Smolyan, Not set
UMHAT Aleksandrovska, Sofia, Not set
Medical Center Synexus Sofia, Sofia, Not set
Medical Center "Nov Rehabilitatsionen center" EOOD, Stara Zagora, Not set
LMC Clin Res Inc. Calgary, Calgary, Alberta
University of Calgary, Calgary, Alberta
The Bailey Clinic, Red Deer, Alberta
BC Diabetes Canada, Vancouver, British Columbia
Commonwealth Medical Clinic, Mount Pearl, Newfoundland and Labrador
Eastern Health Authority, St. Johns, Newfoundland and Labrador
QE II Health - Pharmacy, Halifax, Nova Scotia
Dr. Harpreet Bajaj, Brampton, Ontario
Aggarwal and Assoc Ltd., Brampton, Ontario
JBN Medical Diagnostic Services Inc., Burlington, Ontario
LMC Clin Res Inc. Thornhill, Concord, Ontario
LMC Endo Ctr (Etobicoke) Ltd, Etobicoke, Ontario
Hamilton Med Res Group, Hamilton, Ontario
Premier Clinical Trial Research Network (PCTRN), Hamilton, Ontario
Milestone Research, London, Ontario
LMC Research Inc. Ottawa, Nepean, Ontario
Lakeridge Health, Oshawa, Ontario
Dr. James Cha, Oshawa, Ontario
King Street Research, Oshawa, Ontario
Bluewater Clin Res Group, Inc., Sarnia, Ontario
Bluewater Clin Res Group,Inc, Sarnia, Ontario
Winterberry Family Medicine, Stoney Creek, Ontario
LMC Endo Centres Ltd.(Bayview), Toronto, Ontario
UHN-Toronto General Hospital, Toronto, Ontario
Mount Sinai Hospital, Toronto, Ontario
Dr Anil K Gupta Med Prof Corp, Toronto, Ontario
Dr. Anil K Gupta Med Prof Corp, Toronto, Ontario
Ctr de rech Clin de Laval, Laval, Quebec
Clinique de Recherche Medpharmgene Inc., Montreal, Quebec
Applied Med Inf Res, Montreal, Quebec
Centre Medical Acadie, Montreal, Quebec
Centre de Recherche Saint-Louis, Quebec, Not set
Peking University People's Hospital-Endocrinology, Beijing, Beijing
Peking University People's Hospital, Beijing, Beijing
Beijing Pinggu Hospital-Endocrinology, Beijing, Beijing
The Affiliated Hospital of Jiangsu University-Endocrinology, Zhenjiang, Jiangsu
Jinan Central Hospital, Ji'nan, Shandong
Centre Hospitalier Ardeche Nord, Annonay cedex, Not set
Hospices Civils de Lyon-Hopital Cardiologique Louis Pradel-2, BRON cedex, Not set
Centre Hospitalier Universitaire de Caen Normandie- Cote de Nacre-1, Caen, Not set
Centre Hospitalier Universitaire Grenoble Alpes-Site Nord Michallon-2, Grenoble - Cédex 09, Not set
Centre Hospitalier Departemental Vendee- La Roche Sur Yon, La Roche-sur-yon, Not set
Les Hopitaux de Chartres-Hopital Louis Pasteur, Le Coudray, Not set
Groupe Sos Sante-Hopital Le Creusot-Hotel Dieu-1, Le Creusot, Not set
Groupe SOS Santé Hôtel Dieu, Le Creusot, Not set
Fondation Rothschild, Paris, Not set
Centre Hospitalier Universitaire Reims-Hopital Maison Blanche, Reims, Not set
Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-1, Saint Herblain, Not set
Hôpital Nord Laënnec- Service D'Endocrinologie, Saint Herblain, Not set
Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-2, Toulouse, Not set
Centre de Recherche Clinique Portes Du Sud, Venissieux, Not set
Diabetespraxis Mergentheim, Bad Mergentheim, Not set
Herz- und Diabeteszentrum NRW - Bad Oeynhausen, Bad Oeynhausen, Not set
DaVita Clinical Research Deutschland GmbH, Düsseldorf, Not set
Medizinische Klinik 4, Universitätsklinikum Erlangen, Erlangen, Not set
InnoDiab Forschung GmbH, Essen, Not set
Praxis Dr. med. M. Esser, Essen, Not set
Wendisch/Dahl Hamburg, Hamburg, Not set
Institut für Diabetesforschung GmbH Münster - Dr. med. Rose, Münster, Not set
Zentrum für klinische Studien Alexander Segner, Saint Ingbert-Oberwürzbach, Not set
University Hospital of Athens ATTIKON, Athens, Attica
Iatriko Psychicou Private Clinic, Athens, Not set
General hospital of Athens 'G.Gennimatas', Athens, Not set
Iatriko Athinon 'Palaiou Falirou', Athens, Not set
General Hospital of Athens "Laiko", Nephrology Clinic, Athens, Not set
General Hospital of Lamia, Lamia, Not set
General University Hospital of Patras,Nephrology clinic, Rio, Patra, Not set
AHEPA General University Hospital, Thessaloniki, Not set
"Ippokrateio" G.H. of Thessaloniki, Thessaloniki, Not set
General Hospital of Thessaloniki "Ippokrateio", Thessaloniki, Not set
EUROMEDICA Gen Clinic The/ki, Endocrin,Metabolism,Diabetes, Thessaloniki, Not set
"Thermi" Private Hosital, Thessaloniki, Not set
Genl Hosp of Thessaloniki, Papageorgiou ,Nephrology clinic, Thessaloniki, Not set
PTE-AOK II. Belgyogyaszati Klinika es Nephrologiai Centrum, Pécs, Baranya Vármegye
Lausmed Kft., Baja, Bács-Kiskun Vármegye
Belinus Bt., Debrecen, Hajdu-Bihar Varmegye
Siófoki Kórház, Diabetológiai Szakrendelés, Siófok, Somogy Vármegye
Borbánya Praxis E.Ü. Kft., Nyíregyháza, Szabolcs-Szatmar Varmegye
Péterfy Sándor utcai Kórház, Budapest, Not set
MED-TIMA Kft., Budapest, Not set
Belinus Bt., Debrecen, Not set
Debreceni Egyetem Klinikai Központ Belgyógyászati Klinika D épület, Debrecen, Not set
Debreceni Egyetem Klinikai Központ Belgyógyászati Klinika, Debrecen, Not set
Békés Megyei Központi Kórház, Gyula, Not set
Siófoki Kórház, Diabetológiai Szakrendelés, Siófok, Not set
Markusovszky Egyetemi Oktatókórház, Szombathely, Not set
Markusovszky Egyetemi Oktatókórház, Szombathely, Not set
Endolife Specialty Hospitals, Guntur, Andhra Pradesh
Max Super Speciality Hospital, Saket, New Delhi, Delhi
Ramaiah Memorial Hospital, Bangalore, Karnataka
BGS Global Hospitals, Bangalore, Karnataka
Lifecare Hospital and Research Centre, Bangalore, Karnataka
Amrita Institute Of Medical Sciences & Research Centre, Kochi, Kerala
Calicut Medical College, Kozhikode, Kerala
Seth GS medical college and KEM Hospital, Mumbai, Maharashtra
Poona hospital and research centre, Pune, Maharashtra
The Madras Medical Mission, Chennai, Tamil Nadu
Osmania General Hospital, Hyderabad, Telangana
MV Hospital and Research Centre, Lucknow, Uttar Pradesh
Ajanta ResearchCentre, Lucknow, Uttar Pradesh
Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh
Sanjay Gandhi Postgraduate Institute of Medical Science, Lucknow, Uttar Pradesh
Apollo Multispeciality Hospital, Kolkata, Kolkata, West Bengal
Sir Ganga Ram Hospital, New Delhi, Not set
Diabetes Clinic Wolfson MC, Holon, Not set
Diabetes Unit Hadassah Ein Karem MC, Jerusalem, Not set
Meir Medical Center, Kfar Saba, Not set
Kaplan Medical Center_Rehovot, Rehovot, Not set
Istituto Scientifico San Raffaele, Milano, MI
AOUPol.Giaccone UOC Malattie Endocrine,Ricambio e Nutrizione, Palermo, PA
Presidio Ospedaliero Cisanello, Pisa, PI
AO Papa Giovanni XXIII UOC malattie Endocrine 1-Diabetologia, Bergamo, Not set
Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Not set
Ospedale Maggiore Policlinico UO Endocrinologia Diabetolgia, Milano, Not set
Azienda Ospedaliera Luigi Sacco, Milano, Not set
Azienda Ospealiero Universitaria Policlinico Umberto I, Roma, Not set
Azienda Ospedaliero - Universitaria Sant'Andrea, Roma, Not set
Seino Internal Medicine Clinic, Koriyama-shi, Fukushima, Japan
Manda Memorial Hospital, Sapporo-shi, Hokkaido, Hokkaido, Japan
Jinnouchi Hospital, Kumamoto-shi, Kumamoto, Japan
Heiwadai Hospital, Miyazaki-shi, Miyazaki
New Tokyo Heart Clinic, Chiba, Not set
Fukui Prefectural Hospital_Fukui, Fukui, Not set
Fukuoka Tokushukai Hospital, Fukuoka, Not set
Kawada Clinic, Gunma, Not set
Sasaki Hospital Internal Medicine, Hokkaido, Not set
Sasaki Internal Medicine, Hokkaido, Not set
Nishiyamado Keiwa Hospital, Ibaraki,, Not set
Naka Kinen Clinic, Ibaraki, Not set
Kanazawa Medical University Hospital, Ishikawa, Not set
Yokohama Minoru Clinic, Kanagawa, Not set
H.E.C Science Clinic, Kanagawa, Not set
Shonan Takai Clinic, Kanagawa, Not set
Uji Tokushukai Medical Center, Kyoto, Not set
Kawasaki Medical School Hospital, Okayama, Not set
Takatsuki Red Cross Hospital, Osaka, Not set
Shimizu Clinic Fusa, Saitama, Not set
Oyama East Clinic, Tochigi, Not set
Tokyo Center Clinic, Tokyo, Not set
Fukuwa Clinic, Tokyo, Not set
Juntendo University Hospital_Tokyo, Tokyo, Not set
The University of Tokyo Hospital, Tokyo, Not set
Kato Clinic of Internal Medicine, Tokyo, Not set
Sugawara Clinic, Tokyo, Not set
University Malaya Medical Centre, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
Hospital Sultanah Bahiyah, Alor Setar, Not set
Hospital Raja Permaisuri Bainun Ipoh, Ipoh, Perak, Not set
Sarawak General Hospital, Kuching, Not set
Hospital Pulau Pinang, Pulau Pinang, Not set
Hospital Serdang, Serdang, Not set
Centro de Atención al Diabetico, Actopan, Hidalgo
Inst. Jaliscience de Investigacion en Diabetes y Obesidad SC, Guadalajara, Jalisco
Instituto Nacional de Nutricion - Unidad de Inv de Enf Metab, Distrito Federal, México, D.F.
Instituto Nacional de Ciencias Médicas y Nutrición_Mexico City, Mexico City, México, D.F.
Centro para el Desarrollo de la Medicina y la Asistencia, Culiacán, Sinaloa
Centro de Estudios de Investigación Metabólicos y Cardio, Ciudad Madero, Tamaulipas
Noordwest Ziekenhuisgroep, Alkmaar, Not set
Ziekenhuis Groep Twente Almelo, Almelo, Not set
EB Flevo Research BV, Almere, Not set
Meander Medisch Centrum, Amersfoort, Not set
OLVG West, Amsterdam, Not set
Amsterdam UMC Lokatie VUMC, Amsterdam, Not set
Rijnstate Ziekenhuis, Arnhem, Not set
Tergooi, locatie Hilversum, Hilversum, Not set
Universitair Medisch Centrum Utrecht, Utrecht, Not set
Osteo Medic s.c. Artur Racewicz Jerzy Supronik, Bialystok, Not set
NZOZ WITAMED Poradnia Diabetologiczna, Kielce, Not set
Wojewodzki Szpital Specjalistyczny w Olsztynie, Olsztyn, Not set
Centrum Medyczne "Diabetika", Radom, Not set
Uniwersytecki Szpital Kliniczny Nr 2 PUM W Szczecinie, Szczecin, Not set
Synexus Polska Sp. z o.o. Oddzial w Warszawie, Warszawa, Not set
Miedzyleski Szpital Specjalistyczny, Oddzial Nefrologiczny, Warszawa, Not set
Prywatny Gabinet Janusz Gumprecht, Zabrze, Not set
Reg. State Budget Healthc. Inst. Regional Clinical Hospital, Barnaul, Not set
City Hospital #5, Barnaul, Not set
Road Clinical Hospital at station Chelyabinsk, Chelyabinsk, Not set
PIH "Clin Hosp "RZD-Medicina" former Kazan OJSC Rus Railways, Kazan, Not set
SAHI Kuzbass Hospital(former Regional clinical hospital), Kemerovo, Not set
National Medical Research Center of Endocrinology, Moscow, Not set
LLC RC Medical, Novosibirsk, Not set
Limited Law Company "Healthy Family" Medicine Center", Novosibirsk, Not set
Penza Regional Clinical Hospital named after N.N. Burdenko, Penza, Not set
Aurora MedFort LLC, Saint Petersburg, Not set
Joint Stock Company "Modern Medical Technologies", Saint-Petersburg, Not set
Limited Liability Company "Energiya Zdoroviya", Saint-Petersburg, Not set
Medinet LLC, Saint-Petersburg, Not set
LLC "Endocrinolog", Samara, Not set
SHI Saratov City Clinical Hospital #9, Saratov, Not set
Regional clinical cardiology dispensary, Saratov, Not set
Regional Endocrinological Dispensary, Stavropol, Not set
Ulianovsk Regional Clinical Hospital, Ulianovsk, Not set
Voronezh Regional Clinical Consultive-diagnostic Centre, Voronezh, Not set
Solovyev Clinical Emergency Hospital, Yaroslavl, Not set
Polyclinic #2 in Yoshkar-Ola, Yoshkar-Ola, Not set
MEDISPEKTRUM s.r.o., Bratislava, Not set
FMC - dialyzacne sluzby, s.r.o., Kosice, Not set
Narodny Endokrinologicky a diabetologicky ustav, Lubochna, Not set
IN-DIA s.r.o., Lucenec, Not set
DIABETIK s.r.o., Nitra, Not set
Diabetologicka ambulancia MEDIKARD, s.r.o., Presov, Not set
ARETEUS s.r.o., Trebisov, Not set
MUDr. Jana Rociakova s.r.o., ambulancia vnutorneho lekarstva, Zilina, Not set
FMC- dialyzacne sluzby, s.r.o., Zilina, Not set
MEDIVASA, s.r.o., Diabetologicka ambulancia, Zilina, Not set
Diabetes Care Centre & CDE Centre, Benoni, Gauteng
LCS Clinical Research Unit, Cosmo City, Gauteng
Soweto Clinical Trial Centre, Johannesburg, Gauteng
Hemant Makan, Johannesburg, Gauteng
Wits Bara Clinical Trial Site, Johannesburg, Gauteng
Dr A Amod, Durban, KwaZulu-Natal
Precise Clinical Solutions (Pty) Ltd, Durban, KwaZulu-Natal
Tiervlei Trial Centre, Cape Town, Western Cape
Prof Rayner_Division of Nephrology, Cape Town, Western Cape
Hospital del Mar, Barcelona, Not set
Hospital Vall d'Hebron, Barcelona, Not set
Hospital Público da Mariña, Burela, Not set
Hospital Universitario de Getafe, Getafe, Not set
Hospital Ribera Polusa, Lugo, Not set
Hospital Clínico Universitario de Valencia, Valencia, Not set
Hospital Universitario Doctor Peset, Valencia, Not set
Siriraj Hospital_Bangkoknoi, Bangkok, Bangkoknoi, Bangkok, Bangkok
Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Mueang Chiang Mai District
Phramongkutklao Hospital-nephrology, Bangkok, Rajathewee
King Chulalongkorn Memorial Hospital-Division of Nephrology, Bangkok, Not set
King Chulalongkorn Memorial Hospital_Bangkok, Bangkok, Not set
Phramongkutklao Hospital-nephrology, Bangkok, Not set
Siriraj Hospital-Nephro, Bangkok, Not set
Ankara Universitesi Ibni Sina Hastanesi, Ankara, Not set
Hacettepe Universitesi Tip Fakultesi Nefroloji Bilim Dali, Ankara, Not set
Gazi University Medical Faculty- Nephrology, Ankara, Not set
Akdeniz Universitesi Hastanesi Nefroloji Bilim Dali, Antalya, Not set
Aydin Adnan Menderes University Nephrology, Aydin, Not set
Istanbul University Cerrahpasa Medical Faculty, Istanbul, Not set
Istanbul Universitesi Istanbul Tip Fakultesi- Nefroloji, Istanbul, Not set
Goztepe Egitim Arastirma Hastanesi Nefroloji, Istanbul, Not set
T.C. Saglik Bakanligi Pendik Egitim ve Arastirma Hastanesi, Istanbul, Not set
Ege University Medical Faculty, Izmir, Not set
Kahramanmaras Sutcu Imam University, Kahramanmaras, Not set
Kocaeli University Nephrology Department, Kocaeli, Not set
SI "Institute of Medical and Social Problems of Disability", Dnipro, Not set
Ivano-Frankivsk Regional Clinical Hospital, Ivano-Frankivsk, Not set
CNPI "Kharkiv City Clinical Hospital #27", Kharkiv, Not set
SI "National Institute of Therapy n.a. L.T. Malaya of NAMSU", Kharkiv, Not set
Institute of Endocrinology and Metabolism of AMSU, Kyiv, Not set
CI "1st City Clinical Hospital of Poltava City Council", Poltava, Not set
CI "Zaporizhia city clinical hospital #10", Zaporizhia, Not set
Aberdeen Royal Infirmary, Aberdeen, Not set
Diabetes Centre, Heartlands Hospital, Birmingham, Birmingham, Not set
Ely Bridge Surgery, Cardiff, Not set
Ninewells Hospital, Dundee, Not set
Western General Hospital, Edinburgh, Not set
Glasgow Clinical Research Facility, Glasgow, Not set
The Diabetes Centre, Ipswich, Not set
North Middlesex Hospital, London, Not set
Royal Free - Diabetes, London, Not set
Lister Hospital, Stevenage, Not set
St Georges Hospital, Tooting, Not set
Conditions: Diabetes Mellitus, Type 2
A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight
Active Not Recruiting
This study will look at how well CagriSema helps people with excess body weight lose weight. CagriSema is a new medicine developed by Novo Nordisk that combines cagrilintide and semaglutide. CagriSema cannot yet be prescribed by doctors. In the study, participant will either get CagriSema or dummy medicine and which treatment participant get is decided by chance. The study will last for about 1½ years for each participant.
This study will look at how well CagriSema helps people with excess body weight lose weight. CagriSema is a new medicine developed by Novo Nordisk that combines cagrilintide and semaglutide. CagriSema cannot yet be prescribed by doctors. In the study, participant will either get CagriSema or dummy medicine and which treatment participant get is decided by chance. The study will last for about 1½ years for each participant. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2025
Locations: Aurora FDRC Inc., Costa Mesa, California +23 locations
Aurora FDRC Inc., Costa Mesa, California
Clinical Trial Res Assoc,Inc, Plantation, Florida
Midwest Inst For Clin Res, Indianapolis, Indiana
Accellacare, Wilmington, North Carolina
Velocity Clinical Res-Dallas, Dallas, Texas
Washington Cntr Weight Mgmt, Arlington, Virginia
Capital Clin Res Ctr,LLC, Olympia, Washington
Ocean West Research Clinic, Surrey, British Columbia
Nova Scotia Health Authority, Halifax, Nova Scotia
Wharton Med Clin Trials, Hamilton, Ontario
Hospices Civils de Lyon-Hopital Lyon Sud-1, Pierre-Benite, Not set
Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-1, Saint Herblain, Not set
Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-1, Toulouse Cedex 9, Not set
InnoDiab Forschung GmbH, Essen, Not set
Wendisch/Dahl Hamburg, Hamburg, Not set
AmBeNet GmbH, Leipzig, Not set
Institut für Diabetesforschung GmbH Münster - Dr. med. Rose, Münster, Not set
Forschungszentrum Ruhr KliFoCenter GmbH, Dr. med. Kahrmann, Witten, Not set
The Health Centre, Bradford-on-Avon, Not set
Southmead Hospital, Bristol, Not set
Addenbrooke's Hospital_Cambridge, Cambridge, Not set
WISDEM Centre, Coventry, Not set
The Staploe Medical Centre, Soham, Not set
Joint Clinical Research Facility - Swansea, Swansea, Not set
Conditions: Obesity
Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity
Completed
This study will look at how the participants daily life is affected by their heart failure. The study will also look at the change in participants body weight from the start to the end of the study. This is to compare the effect on heart failure symptoms and on body weight in people taking semaglutide (a new medicine) to people taking "dummy" medicine.
Participants will either get semaglutide or "dummy" medicine - which treatment participants get is decided by chance. Participants will need to... Read More
This study will look at how the participants daily life is affected by their heart failure. The study will also look at the change in participants body weight from the start to the end of the study. This is to compare the effect on heart failure symptoms and on body weight in people taking semaglutide (a new medicine) to people taking "dummy" medicine.
Participants will either get semaglutide or "dummy" medicine - which treatment participants get is decided by chance. Participants will need to take 1 injection once a week. The study medicine is injected with a thin needle in a skin fold in the stomach area, thigh or upper arm.
During the study participants will have talks with the study staff about healthy lifestyle choices including healthy food and physical activity.
The study will last for approximately 59 weeks. Participants will have 11 clinic visits and 1 phone call with the study doctor. Women: Women cannot take part if they are pregnant, breast-feeding or plan to become pregnant during the study period. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2025
Locations: Eastern Shore Rsrch Inst, LLC, Fairhope, Alabama +92 locations
Eastern Shore Rsrch Inst, LLC, Fairhope, Alabama
Northwest Heart Clin. Res., Arlington Heights, Illinois
Northwestern University_Chicago_0, Evanston, Illinois
Chicago Medical Research LLC, Hazel Crest, Illinois
University of Kansas Medical Center, Kansas City, Kansas
Cotton-O'Neil Heart Center, Topeka, Kansas
The Research Group of Lexington LLC, Lexington, Kentucky
Baptist Health Louisville, Louisville, Kentucky
Heart Clinic of Hammond, Hammond, Louisiana
John Hopkins Hospital, Baltimore, Maryland
Mayo Clinic Rochester, Rochester, Minnesota
Saint Luke's Hospital of Kansas City, Kansas City, Missouri
St Louis Heart & Vascular, P.C., Saint Louis, Missouri
St Francis Hospital Lindner Research Center, Greenvale, New York
NY Presbyt Hosp-W Cornell Med, New York, New York
Wake Forest School of Medicine, Winston-Salem, North Carolina
Lindner Center,Christ Hospital, Cincinnati, Ohio
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
Hospital of University of Pennsylvania, Philadelphia, Pennsylvania
University of Texas Southwestern Medical Center, Dallas, Texas
CEMEDIC, Caba, Buenos Aires
Instituto de Cardiología de Corrientes, Corrientes, Buenos Aires
Centro de Investigación y Prevención Cardiovascular, Caba, Not set
Centro de Investigación y Prevención Cardiovascular, Caba, Not set
CEMEDIC, Caba, Not set
Cardiología Palermo, Ciudad Autónoma de Buenos Aire, Not set
Instituto de Cardiología de Corrientes, Corrientes, Not set
Consultorio Integral de Atención al Diabético, Morón, Not set
Sanatorio Britanico S.A., Rosario, Santa Fe, Not set
The Canberra Hospital_Garran, Garran, Australian Capital Territory
Concord Repatriation General Hospital - Cardiology, Concord, New South Wales
Liverpool Hospital, Liverpool, New South Wales
Flinders Medical Centre, Bedford Park, South Australia
Geelong Cardiology Research Unit, Geelong, Victoria
Cambridge Cardiac Care Centre, Cambridge, Ontario
Partnrs Adv Cardio Eval (PACE), Newmarket, Ontario
Heart Health Institute Research, Inc., Scarborough, Ontario
Institut Universitaire de Cardiologie et de Pneumologie. de Quebec - Universite Laval, Quebec, Not set
Nemocnice Jihlava Kardiologie, Jihlava, Not set
Vseobecna fakultni nemocnice a 1 LF UK v Praze, Praha 2, Not set
IKEM, Praha 4, Not set
MEDICON a.s., Praha 7, Not set
Poliklinika Holešovice VISIONARY - Medicon Pharm s.r.o., Praha 7, Not set
Nemocnice Slany Kardiologie, Slany, Not set
Nemocnice Tábor a.s., Tábor, Not set
Herlev og Gentofte Hospital, Hellerup, Region Hovedstaden
Aarhus Universitetshospital, Hjertesygdomme, Aarhus N, Not set
Kardiologisk Odense & Svendborg, Svendborg, Not set
Charité - Campus Virchow-Klinikum - Kardiologie, Angiologie und Intensivmedizin (CRU), Berlin, Not set
MVZ "Am Felsenkeller" (Dresden), Dresden, Not set
Zentrum fuer klinische Studien Suedbrandenburg GmbH, Elsterwerda, Not set
MVZ CCB Frankfurt Und Main-Taunus GbR, Frankfurt, Not set
Medical Center - University Of Freiburg, Freiburg, Not set
Appel, Kassel, Not set
Universitatsklinikum Würzburg - Zentrum für Herzinsuffizienz, Würzburg, Not set
Lausmed Kft., Baja, Bács-Kiskun Vármegye
Selye János Kórház, Komárom, Komárom-Esztergom
Szent Margit Rendelőintézet Nonprofit Kft., Budapest, Not set
Semmelweis Egyetem Szent Rókus Klinikai Tömb, Budapest, Not set
Gottsegen György Országos Kardiológiai Intézet, Budapest, Not set
Semmelweis Egyetem Városmajori Szív- és Érgyógyászat, Budapest, Not set
Jahn Ferenc Dél-pesti Kórház és Rendelőintézet, Budapest, Not set
Borsod-Abaúj-Zemplén Megyei Központi Kórház, Miskolc, Not set
Zala Megyei Szent Rafael Kórház, Zalaegerszeg, Not set
Hadassah Ein Kerem MC - Cardio, Jerusalem, Not set
Cardiology department, Western Galilee Medical Center, Nahariya, Not set
Heart Failure Unit, Rabin Medical Center - Beilinson Campus, Petah-Tikva, Not set
Cardio Vascular Research Center Sourasky MC, Tel Aviv, Not set
Sheba Medica Center - Clinical Research Unit, Tel Hashomer, Not set
Gelre Ziekenhuizen Apeldoorn, Apeldoorn, Not set
Rode Kruis Ziekenhuis Beverwijk, Beverwijk, Not set
UMC Groningen, Groningen, Not set
Saxenburgh Medisch Centrum, Hardenberg, Not set
Medisch Centrum Leeuwarden, Leeuwarden, Not set
Bravis Ziekenhuis, Roosendaal, Not set
Uniwersytecki Szpital Kliniczny nr 2 Uniwersytetu Medycznego w Łodzi, Lodz, Lodzkie
Malopolskie Centrum Sercowo-Naczyniowe, Chrzanow, Malopolskie
Uniwersytecki Szpital Kliniczny w Bialymstoku K. Kardio, Bialystok, Podlaskie
Ind. Prak. Lek. w dziedz. Kardiologii lek. med. K. Cymerman, Gdynia, Not set
I Katedra i Klinika Kardiologii WUM SPCSK, Warsaw, Not set
Pro Familia Altera Sp. z o.o., Katowice, Śląskie
Hospital Universitario La Zarzuela, Madrid, Not set
Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Not set
Hospital Clínico Universitario de Valencia, Valencia, Not set
St. Richards Hospital, Chichester, West Sussex
Southmead Hospital, Bristol, Not set
Ninewells Hospital, Dundee, Not set
Glasgow Clinical Research Facility, Glasgow, Not set
Queen Elizabeth University Hospital, Glasgow, Not set
Wycombe General Hospital, High Wycombe, Not set
University Hospital Aintree, Liverpool, Not set
Manchester Royal Infirmary_Manchester_0, Manchester, Not set
Great Western Hospital, Swindon, Not set
Conditions: Obesity
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
Active Not Recruiting
This study will look at how well semaglutide helps children and teenagers losing weight. This will be tested by comparing the effect on body weight in children and teenagers taking semaglutide in comparison to placebo, a "dummy" medicine. In addition to taking the medicine, the child's parent and the child will have talks with study staff about healthy food choices, how to be more physically active and what your child can do to try to lose weight. The child will either get semaglutide or a "dumm... Read More
This study will look at how well semaglutide helps children and teenagers losing weight. This will be tested by comparing the effect on body weight in children and teenagers taking semaglutide in comparison to placebo, a "dummy" medicine. In addition to taking the medicine, the child's parent and the child will have talks with study staff about healthy food choices, how to be more physically active and what your child can do to try to lose weight. The child will either get semaglutide or a "dummy" medicine. Which treatment the child will get is decided by chance. Semaglutide is an approved medicine for type 2 diabetes and weight management in adults.
The child will get one injection once a week. The study medicine is injected with a thin needle in the stomach, thighs or upper arms. The study will last for about 2 ½ years (132 weeks). Read Less
Gender:
ALL
Ages:
Between 6 years and 18 years
Trial Updated:
01/28/2025
Locations: Neighborhood Healthcare, Escondido, California +44 locations
Neighborhood Healthcare, Escondido, California
Yale School of Medicine, New Haven, Connecticut
Columbus Research Foundation, Columbus, Georgia
Eastside Bariatric and Gen Surg, Snellville, Georgia
Solaris Clinical Research, Meridian, Idaho
Pennington Biom Res Ctr, Baton Rouge, Louisiana
Clinical Trials of America LLC, Monroe, Louisiana
Barry J. Reiner, MD LLC, Baltimore, Maryland
University of Minnesota, Minneapolis, Minnesota
Mississippi Center for Advanced Medicine, Madison, Mississippi
UBMD Peds-Div of Endo/Diabetes, Buffalo, New York
Valley Weight Loss Clinic, Fargo, North Dakota
Centricity Research - Ohio, Columbus, Ohio
UPMC Child Hosp-Pittsburgh, Pittsburgh, Pennsylvania
Tullahoma Pediatrics PLLC, Tullahoma, Tennessee
Texas Diabetes & Endocrinology, Austin, Texas
Univ Of Texas Hlth Science Cntr, San Antonio, Texas
Health Res of Hampton Roads, Newport News, Virginia
Universitätsklinik Kinder-Jugendheilkunde Innsbruck, Innsbruck, Not set
Universitätsklinik für Kinder und Jugendheilkunde Haus E, Salzburg, Not set
UZ Brussel, Brussel, Not set
UZ Antwerpen - UZA - Kinderziekenhuis, Edegem, Not set
UZA - UZ Antwerpen - Kinderziekenhuis, Edegem, Not set
UZ Leuven - Kindergeneeskunde, Leuven, Not set
Aalborg Universitetshospital, Aalborg, Not set
Aarhus Universitetshospital, Steno Diabetes Center Aarhus, Aarhus, Not set
Holbæk Sygehus, Holbæk, Not set
Auf der Bult - Klinik für Diabetologie, Endokrinologie, Gastroenterologie und Klinische Forschung, Hannover, Not set
Kinder- und Jugendkrankenhaus, Hannover, Not set
Universitätsklinikum Leipzig - Klinik und Poliklinik für Kinder- und Jugendmedizin, Leipzig, Not set
Universitätsklinikum Leipzig, Klinik und Poliklinik für Kinder- und Jugendmedizin, Leipzig, Not set
Universitätsklinikum Ulm für Kinder- und Jugendmedizin, Ulm, Not set
Rambam Medical Center Children A Dept., Haifa, Not set
Endrocrinology & DM Schneider MC, Petah Tikva, Not set
Shamir (Assaf Harofe) Medical Center, Zerifin, Not set
Consultorio de Endocrinología y Pediatría, Puebla, Not set
Hospital da Luz, Lisboa, Not set
Unidade Local de Saúde de Santo António, E.P.E, Porto, Not set
CUF-Porto, Porto, Not set
Hallands sjukhus Halmstad, Halmstad, Not set
Akademiska sjukhuset Uppsala, Uppsala, Not set
Birmingham Children's Hospital, Birmingham, Not set
University Hospitals Bristol & Weston NHS Foundation Trust, Bristol, Not set
Leeds Children's Hospital, Leeds, Not set
Alder Hey Children's Hospital, Liverpool, Not set
Conditions: Obesity
A Study of Cotadutide in Participants Who Have Chronic Kidney Disease With Type 2 Diabetes Mellitus
Completed
A Phase 2b, study to measure the effect of Cotadutide at different doses versus placebo or comparator (semaglutide) in participants who have Chronic Kidney Disease with Type 2 Diabetes Mellitus.
A Phase 2b, study to measure the effect of Cotadutide at different doses versus placebo or comparator (semaglutide) in participants who have Chronic Kidney Disease with Type 2 Diabetes Mellitus. Read Less
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
12/06/2024
Locations: Research Site, Box Hill, Not set +82 locations
Research Site, Box Hill, Not set
Research Site, Elizabeth Vale, Not set
Research Site, Fitzroy, Not set
Research Site, Heidelberg, Not set
Research Site, Melbourne, Not set
Research Site, Merewether, Not set
Research Site, Oaklands Park, Not set
Research Site, Wollongong, Not set
Research Site, Woolloongabba, Not set
Research Site, Vancouver, British Columbia
Research Site, Barrie, Ontario
Research Site, Brampton, Ontario
Research Site, Concord, Ontario
Research Site, Etobicoke, Ontario
Research Site, Oakville, Ontario
Research Site, Oshawa, Ontario
Research Site, Ottawa, Ontario
Research Site, Toronto, Ontario
Research Site, Toronto, Ontario
Research Site, Waterloo, Ontario
Research Site, Laval, Quebec
Research Site, Montreal, Quebec
Research Site, Berlin, Not set
Research Site, Berlin, Not set
Research Site, Berlin, Not set
Research Site, Dortmund, Not set
Research Site, Dusseldorf, Not set
Research Site, Essen, Not set
Research Site, Kassel, Not set
Research Site, Ludwigshafen, Not set
Research Site, Magdeburg, Not set
Research Site, Mainz, Not set
Research Site, München, Not set
Research Site, Münster, Not set
Research Site, Münster, Not set
Research Site, Riesa, Not set
Research Site, Sankt Ingbert, Not set
Research Site, Arakawa-ku, Not set
Research Site, Chitose-shi, Not set
Research Site, Fujisawa-shi, Not set
Research Site, Kamakura-shi, Not set
Research Site, Obihiro-shi, Not set
Research Site, Sapporo-shi, Not set
Research Site, Shinjyuku-ku, Not set
Research Site, Auckland, Not set
Research Site, Auckland, Not set
Research Site, Christchurch, Not set
Research Site, Grafton, Not set
Research Site, Havelock North, Not set
Research Site, New Plymouth, Not set
Research Site, Tauranga, Not set
Research Site, Wellington, Not set
Research Site, Białystok, Not set
Research Site, Grodzisk Mazowiecki, Not set
Research Site, Katowice, Not set
Research Site, Krakow, Not set
Research Site, Krakow, Not set
Research Site, Kraków, Not set
Research Site, Lublin, Not set
Research Site, Poznań, Not set
Research Site, Skierniewice, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Wierzchosławice, Not set
Research Site, Barcelona, Not set
Research Site, Cordoba, Not set
Research Site, L'Hospitalet de Llobregat, Not set
Research Site, La Coruna, Not set
Research Site, Lérida, Not set
Research Site, Madrid, Not set
Research Site, Majadahonda, Not set
Research Site, Malaga, Not set
Research Site, Palma de Mallorca, Not set
Research Site, Palma, Not set
Research Site, Pozuelo de Alarcón, Not set
Research Site, Sevilla, Not set
Research Site, Sevilla, Not set
Research Site, Valencia, Not set
Research Site, Vitoria, Not set
Research Site, Dundee, Not set
Research Site, Liverpool, Not set
Research Site, London, Not set
Conditions: Type 2 Diabetes Mellitus, Chronic Kidney Diseases
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