All Clinical Trials in United Kingdom

A listing of 3097 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Study of Oral Atogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

NCT06806293

Recruiting

A migraine attack is a moderate or severe headache that usually occurs on one side of the head and is often throbbing or pulsating. The headache is often accompanied by sensitivity to light, sensitivity to sound, nausea, or other symptoms. Menstrual migraine (MM) attacks are migraine attacks that occur in individuals before or during their menstrual period. The main goals of the study are to evaluate the efficacy (how well the medicine works), safety, and tolerability (the degree to which any ad... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Chinese PLA General Hospital /ID# 267141, Beijing, Beijing +88 locations

Chinese PLA General Hospital /ID# 267141, Beijing, Beijing

Nanfang Hospital - Southern Medical University /ID# 268510, Guangzhou, Guangdong

Hebei General Hospital /ID# 267663, Shijiazhuang, Hebei

Renmin Hospital of Wuhan University /ID# 267671, Wuhan, Hubei

The First Affiliated Hospital of Soochow University /ID# 267885, Suzhou, Jiangsu

Shaanxi Provincial People'S Hospital /ID# 267827, XI An, Shaanxi

First Affiliated Hospital of Shanxi Medical University /ID# 267680, Taiyuan, Shanxi

Tianjin Medical University General Hospital /ID# 268846, Tianjin, Tianjin

Tianjin People's Hospital /ID# 268511, Tianjin, Tianjin

The Second Affiliated Hospital of Zhejiang University School of Medicine /ID# 267994, Hangzhou, Zhejiang

A-Shine s.r.o. /ID# 266048, Plzen, Plzensky Kraj

Všeobecná Fakultní Nemocnice v Praze /ID# 268100, Praha, Praha 17

MINKSneuro s.r.o /ID# 267651, Brno, Not set

Neurologie Brno /ID# 266050, Brno, Not set

NeuroHK s.r.o. /ID# 266051, Hradec Kralove, Not set

Neuro plus s.r.o. /ID# 266052, Olomouc, Not set

Clintrial s.r.o. /ID# 266047, Prague 10, Not set

DADO MEDICAL s.r.o. /ID# 267629, Prague, Not set

Pratia Prague s.r.o. /ID# 268252, Prague, Not set

Fakultni Thomayerova nemocnice /ID# 266049, Praha, Not set

Neuro Centrum Odenwald - Praxis Erbach /ID# 276171, Erbach, Hessen

Universitaetsmedizin Greifswald /ID# 267277, Greifswald, Mecklenburg-Vorpommern

Studienzentrum Nord-West /ID# 267311, Westerstede, Niedersachsen

Neurozentrum Bielefeld /ID# 276170, Bielefeld, Nordrhein-Westfalen

Klinikum Ibbenbueren /ID# 267393, Ibbenbüren, Nordrhein-Westfalen

ZNS Siegen /ID# 268247, Siegen, Nordrhein-Westfalen

Pharmakologisches Studienzentrum Chemnitz GmbH /ID# 267285, Chemnitz, Sachsen

Ambenet Hausarztpraxis /ID# 267309, Leipzig, Sachsen

Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 267310, Berlin, Not set

MIND Clinic /ID# 267652, Budapest, Not set

Cortex Study Center /ID# 266639, Budapest, Not set

Clinexpert Kft /ID# 266644, Budapest, Not set

Semmelweis Egyetem /ID# 266636, Budapest, Not set

Semmelweis Egyetem /ID# 266752, Budapest, Not set

UNO Medical Trials /ID# 266643, Budapest, Not set

S-Medicon Kft /ID# 266637, Budapest, Not set

Uzsoki Utcai Kórház /ID# 266641, Budapest, Not set

Fondazione IRCCS Istituto Neurologico Carlo Besta /ID# 267062, Milan, Milano

Istituto Auxologico Italiano - Ospedale San Luca /ID# 276161, Milan, Milano

Azienda Ospedaliera Universitaria Luigi Vanvitelli /ID# 267023, Naples, Napoli

Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 266859, Rome, Roma

ICOT Istituto Marco Pasquali /ID# 267288, Latina, Not set

Fondazione Mondino Istituto Neurologico Nazionale a Carattere Scientifico IRCCS /ID# 267922, Pavia, Not set

Azienda Ospedaliera di Perugia - Ospedale S. Maria della Misericordia /ID# 267926, Perugia, Not set

ASU FC - P.O. Universitario Santa Maria della Misericordia /ID# 267019, Udine, Not set

Konan Medical Center /ID# 266867, Kobe-shi, Hyogo

Fujitsu Clinic /ID# 266877, Kawasaki-shi, Kanagawa

Umenotsuji Clinic /ID# 266834, Kochi-shi, Kochi

Sendai Headache and Neurology Clinic Medical Corporation /ID# 266864, Sendai-shi, Miyagi

Ooba Clinic for Neurosurgery & Headache /ID# 266866, Oita-shi, Oita

Chibune General Hospital /ID# 266874, Osaka-shi, Osaka

Tominaga Clinic - Osaka /ID# 268228, Osaka-shi, Osaka

Usuda Clinic Of Internal Medicine /ID# 266870, Setagaya-ku, Tokyo

Tokyo Headache Clinic /ID# 266863, Shibuya-ku, Tokyo

Nagaseki Headache Clinic /ID# 266865, Kai, Yamanashi

Hallym University Dongtan Sacred Heart Hospital /ID# 267473, Hwaseong, Gyeonggido

Nowon Eulji Medical Center, Eulji University /ID# 267474, Seoul, Seoul Teugbyeolsi

Seoul National University Hospital /ID# 267477, Seoul, Seoul Teugbyeolsi

Kangbuk Samsung Hospital /ID# 267475, Seoul, Seoul Teugbyeolsi

Yonsei University Health System Severance Hospital /ID# 267476, Seoul, Seoul Teugbyeolsi

Athleticomed Sp. z o.o /ID# 266434, Bydgoszcz, Kujawsko-pomorskie

SPZOZ Szpital Uniwersytecki w Krakowie /ID# 266443, Krakow, Malopolskie

Instytut Zdrowia Dr Boczarska Jedynak /ID# 266073, Oświęcim, Malopolskie

Centrum Badan Klinicznych PI-House sp. z o.o. /ID# 266732, Gdansk, Pomorskie

Novo-Med Zielinski i wspolnicy SP. J. /ID# 266433, Katowice, Slaskie

Neuro-Care Sp. z o.o. sp.k /ID# 267883, Katowice, Slaskie

Solumed Centrum Medyczne /ID# 267220, Poznan, Wielkopolskie

MIGRE Polskie Centrum Leczenia Migreny Anna Gryglas-Dworak /ID# 266437, Wroclaw, Not set

Unidade Local de Saude do Alto Ave, EPE /ID# 266168, Guimaraes, Braga

Hospital da Luz /ID# 266182, Lisbon, Lisboa

Unidade Local de Saude de Loures-Odivelas, EPE /ID# 266190, Loures, Lisboa

Unidade Local de Saude de Matosinhos, EPE /ID# 266170, Senhora da Hora, Porto

Unidade Local de Saude de Almada-Seixal, EPE /ID# 276215, Almada, Setubal

Unidade Local de Saude da Regiao de Aveiro, EPE /ID# 266187, Aveiro, Not set

2CA-Braga, Hospital de Braga /ID# 276218, Braga, Not set

Unidade Local de Saude de Santa Maria, EPE /ID# 275932, Lisboa, Not set

Unidade Local de Saude Sao Joao, EPE /ID# 266185, Porto, Not set

Unidade Local de Saude da Arrabida, EPE /ID# 266183, Setubal, Not set

Hospital Clinico Universitario de Valladolid /ID# 275899, Valladolid, Not set

China Medical University Hospital /ID# 266423, Taichung, Not set

National Cheng Kung University Hospital /ID# 267754, Tainan, Not set

Mackay Memorial Hospital /ID# 266421, Taipei City, Not set

Taipei Veterans General Hospital /ID# 266418, Taipei City, Not set

Linkou Chang Gung Memorial Hospital /ID# 266424, Taoyuan City, Not set

Royal Sussex County Hospital /ID# 268362, Brighton, East Sussex

St Pancras Clinical Research /ID# 268653, London, Greater London

Breckland Alliance /ID# 268772, Thetford, Norfolk

Oxford University Hospitals - John Radcliffe Hospital /ID# 267659, Oxford, Oxfordshire

The Adam Practice /ID# 268116, Poole, Not set

Conditions: Menstrual Migraine (MM)

Learn More ›

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

NCT06876649

Recruiting

The master protocol study J2N-MC-JZNY provides a framework to enable the evaluation of the long-term safety and efficacy of pirtobrutinib after completion of clinical studies evaluating pirtobrutinib. The clinical studies that will feed into this master protocol are referred to as originator studies. The master protocol will govern individual study-specific appendices (ISAs) that will represent participants from the individual, completed originator studies. These participants will have the oppor... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Sylvester Comprehensive Cancer Center, Miami, Florida +35 locations

Sylvester Comprehensive Cancer Center, Miami, Florida

Florida Cancer Specialists, Sarasota, Florida

The Emory Clinic, Atlanta, Georgia

Northwestern University, Chicago, Illinois

Dana-Farber Cancer Institute, Boston, Massachusetts

Mayo Clinic- Minnesota, Rochester, Minnesota

University Of Nebraska Medical Center, Omaha, Nebraska

Cayuga Cancer Center, Ithaca, New York

Northwell Health, Lake Success, New York

Memorial Sloan-Kettering Cancer Center (MSKCC) - New York, New York, New York

Duke University Medical Center, Durham, North Carolina

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

University of Pennsylvania Hospital, Philadelphia, Pennsylvania

Tennessee Oncology, Nashville, Tennessee

University of Texas MD Anderson Cancer Center, Houston, Texas

Swedish Cancer Institute, Seattle, Washington

Medical College of Wisconsin, Milwaukee, Wisconsin

Flinders Medical Centre, Adelaide, South Australia

Peter MacCallum Cancer Centre, Melbourne, Victoria

Linear Clinical Research, Victoria, Not set

CHU de Nantes - Hotel Dieu, Nantes Cedex 1, Loire Atlantique

Ospedale San Raffaele, Milano, Lombardia

IRCCS-AOU di Bologna-Policlinico S.Orsola-Malpighi, Bologna, Not set

Tokai University Hospital- Isehara Campus, Isehara, Kanagawa

National Cancer Center Hospital, Cho-ku, Tokyo

Nagoya Medical Center, Aichi-Ken, Not set

National Hospital Organization Kyushu Cancer Center, Fukuoka, Not set

Tohoku University Hospital, Miyagi-Ken, Not set

Hokkaido University Hospital, Sapporoshi, Not set

Seoul National University Hospital, Seoul, Korea

Pratia MCM Krakow, Krakow, Not set

Instytut Hermatologii I Transfuzjologii, Warsaw, Not set

Derriford Hospital, Plymouth, Devon

Churchill Hospital, Oxford, Oxfordshire

St James's University Hospital, Leeds, West Yorkshire

Conditions: Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma

Learn More ›

Artificial Intelligence Delivered Cardiac Magnetic Resonance - Prospective Validation

NCT06061822

Recruiting

Cardiac MRI (CMR) scanning allows doctors to create detailed images of the heart. However, the need for experienced cardiac radiographers to perform each scan can make CMR's delivery difficult, and some patients in the UK wait more than half a year for a scan. These radiographers must take pictures of different part of the heart, termed "views", each of which must be precisely positioned. The investigators believe they can revolutionise CMR, by using artificial intelligence to automatically pos... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Imperial College Healthcare NHS Trust, London, Not set

Conditions: Cardiovascular Diseases, Healthy Volunteers

Learn More ›

Fibrosis Lessens After Metabolic Surgery

NCT06374875

Recruiting

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), a major global public health concern, is commonly associated with obesity, diabetes, and dyslipidemia. MASLD is currently the most common cause of chronic liver disease affecting about 80% of people with obesity, ranging from simple fat deposits in the liver to Metabolic Dysfunction-Associated Steatohepatitis (MASH), cellular injury, advanced fibrosis, cirrhosis, or hepa... Read More

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/18/2025

Locations: Banner Health Center, Phoenix, Arizona +21 locations

Conditions: Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-Alcoholic Fatty Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Liver Fibrosis, Obesity

Learn More ›

A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works

NCT05744921

Recruiting

This study is researching an experimental treatment combination with two experimental drugs called pozelimab and cemdisiran. The study is focused on people with paroxysmal nocturnal hemoglobinuria (PNH). The aim of this study is to see how safe and effective the pozelimab + cemdisiran combination is for people with PNH in the long term. The pozelimab + cemdisiran combination may be referred to as "study drugs" in this section. This study is looking at several other research questions, including... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Toronto General Hospital, Toronto, Ontario +35 locations

Toronto General Hospital, Toronto, Ontario

Semmelweis University/Semmelweis Egyetem, Budapest, Not set

Rajiv Gandhi Cancer Institute & Research Center (RGCIRC) - Rohini Campus, New Delhi, Delhi

Amrita Institute of Medical Sciences (AIMS) and Research Centre Aims, Kochi, Kerala

Bhagwan Mahaveer Cancer Hospital and Research Centre (BMCHRC), Jaipur, Not set

Aou Careggi, Firenze, Florence

SC Hematology, AOU Città della Salute e della Scienza di Torino, Torino, Not set

University of Tsukuba Hospital, Tsukuba, Ibaraki

Ajou University Medical Center, Suwon-si, Gyeonggi-do

St. Vincent Hospital, Suwon, Gyeonggi

Gachon University Gil Medical Center, Incheon, Namdong-Gu

Pusan National University Hospital, Busan, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Ewha Womans University Mokdong Hospital, Seoul, Not set

Hospital Tg Ampuan Afzan, Kuantan, Pahang

Hospital Queen Elizabeth, Kota Kinabalu, Sabah

Hospital Ampang, Ampang, Selangor

Clinica San Felipe, Lima, Not set

St Lukes Medical Center, Quezon City, National Capital Region

Szpital Uniwersytecki Nr2 Bydgoszcz, Bydgoszcz, Not set

Prof Dr Ion Chiricuta Cancer Institute, Cluj Napoca, Cluj

National University Hospital, Singapore, Not set

Hospital Universitario Basurto, Bilbao, Bizkaia

Hospital Clinic de Barcelona, Barcelona, Not set

Chang Gung Memorial Hospital - Linkou Branch, Taoyuan, Hunan Province

Hualien Tzu Chi Hospital, Hualien City, Not set

China Medical University Hospital, Taichung, Not set

Tri-Service General Hospital, Taipei City, Not set

National Taiwan University Hospital, Taipei, Not set

Prince Of Songkla Hospital, Prince Of Songkhla University, Hat-Yai, Songkhla

King Chulalongkorn Memorial Hospital, Bangkok, Not set

Chiang Mai University, Chiang Mai, Not set

Srinagarind Hospital, Khon Kaen, Not set

Ege University Faculty of Medicine, Bornova, Izmir

Leeds Teaching Hospitals NHS Trust - St. James Institute of Oncology, Leeds, Not set

Conditions: Paroxysmal Nocturnal Hemoglobinuria

Learn More ›

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

NCT06697301

Recruiting

The study is for patients with advanced melanoma who are eligible for standard therapy with Pembrolizumab.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Ironwood Cancer & Research Centers, Chandler, Arizona +56 locations

Ironwood Cancer & Research Centers, Chandler, Arizona

The Oncology Institution of Hope and Innovation, Los Angeles, California

Providence Medical Foundation, Santa Rosa, California

UCHealth Memorial Hospital Central, Colorado Springs, Colorado

Bioresearch Partner, Hialeah, Florida

Washington University School of Medicine in St. Louis, Saint Louis, Missouri

Gabrail Cancer Center Research LLC, Canton, Ohio

University of Pittsburgh Medical Center(UPMC)-Hillman Cancer Center, Pittsburgh, Pennsylvania

Cancer Care Wollongong, Wollongong, New South Wales

Icon Cancer Centre Chermside, Chermside, Queensland

Southern Adelaide Local Health Network Incorporated Flinders Medical Centre, Bedford Park, South Australia

Eastern Health, Box Hill, Victoria

Universitätsklinikum Graz, Graz, Styria

Universitair Ziekenhuis Antwerpen, Edegem, Antwerpen

Centre Hospitalier Universitaire Universite Catholique de Louvain - Site Godinne, Yvoir, Namur

Universitair Ziekenhuis Leuven - Campus Gasthuisberg, Leuven, Vlaams Brabant

Algemeen Ziekenhuis Groeninge - Campus Kennedylaan, Kortrijk, West-Vlaanderen

Cliniques Universitaires Saint-Luc, Brussels, Not set

Sunnybrook Research Ins<tute, Toronto, Ontario

Masaryk Memorial Cancer Institute, Brno, Not set

Aarhus Universitetshospital, Aarhus, Midtjylland

Aalborg University Hospital, Aalborg, Nord Jutland

Oulu University Hospital, Oulu, Not set

Centre Hospitalier Universitaire Grenoble Alpes, La Tronche, Isère

Centre Hospitalier Lyon-Sud, Pierre-Bénite, Rhone-Alpes

CHU Rouen, Rouen, Not set

Universitätsmedizin Mannheim, Mannheim, Baden-Württemberg

Universitätsklinikum Tübingen, Tübingen, Baden-Württemberg

Universitat Leipzig, Saxony, Leipzig

Elbe Kliniken Stade-Buxtehude, Buxtehude, Lower Saxony

Johannes Wesling Klinikum Minden, Minden, Nordrhein-Westfalen

University of Mainz Medical Center, Mainz, RLP

Universitätsklinikum Schleswig-Holstein - Campus Kiel, Kiel, Schleswig-Holstein

Universitätsklinikum Schleswig-Holstein - Campus Lübeck, Lübeck, Schleswig-Holstein

Soroka medical center, Be'er Sheva, Not set

Rabin Medical Center, Petach Tikva, Not set

Ella Lemelbaum Institute for Immuno-Oncology and Melanoma, Ramat Gan, Not set

Tel Aviv Medical Center, Tel Aviv, Not set

Auckland City Hospital, Auckland, Not set

Christchurch Public Hospital, Christchurch, Not set

Oslo University Hospital - The Norwegian Radium Hospital, Oslo, Not set

Hospital da Luz Lisboa, Lisboa, Not set

Cancercare Port Elizabeth - Langenhoven Drive Oncology Centre, Port Elizabeth, Eastern Cape

The Medical Oncology Centre of Rosebank, Saxonwold, Gauteng

Cape Town Oncology Trials, Cape Town, Western Cape

TASK Eden, George Central, Western Cape

Hospital Universitari Dexeus, Barcelona, Not set

Vall d' Hebron Institute of Oncology, Barcelona, Not set

Institut Català d'Oncologia Girona (ICO Girona), Girona, Not set

GenesisCare Madrid - Hospital San Francisco de Asís, Madrid, Not set

Hospital Universitario Virgen de la Victoria, Málaga, Not set

IVO - Fundacion Instituto Valenciano de Oncologia, Valencia, Not set

INCLIVA Instituto de Investigación Sanitaria, Valencia, Not set

Gävle Sjukhus, Gävle, Gävleborgs Län

Universitätsspital Zürich, Zürich, Not set

Guy's and St Thomas' NHS Foundation Trust, London, England

Sarah Cannon Research Institute London, London, England

Conditions: Advanced Melanoma

Learn More ›

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

NCT06548542

Recruiting

Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most frequently affecting the bowels. It can cause many different symptoms including belly pain, diarrhea, tiredness, and weight loss. Treatments are available but do not work the same for all patients or may stop working over time. This study will evaluate the effectiveness and adverse events of targeted therapies (TaTs) for adult participants with moderate to severe CD.... Read More

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/18/2025

Locations: Digestive Health Specialists /ID# 266216, Dothan, Alabama +222 locations

Digestive Health Specialists /ID# 266216, Dothan, Alabama

East View Medical Research /ID# 270377, Mobile, Alabama

Southern California Res. Ctr /ID# 265549, Coronado, California

UC San Diego Health System /ID# 265565, La Jolla, California

uc davis medical center - patient support services building /ID# 265554, Sacramento, California

Clinical Applications Laboratories - San Diego - 3rd Avenue /ID# 267391, San Diego, California

Peak Gastroenterology Associates - Colorado Springs - North Cascade Avenue /ID# 265557, Colorado Springs, Colorado

Danbury Hospital, Western Connecticut Health Network /ID# 265556, Danbury, Connecticut

Yale University School of Medicine /ID# 266786, New Haven, Connecticut

Nature Coast Clinical Research - Inverness /ID# 265874, Inverness, Florida

Atlantic Medical Research /ID# 266207, Margate, Florida

A Plus Research /ID# 265878, Miami, Florida

Sanchez Clinical Research /ID# 265887, Miami, Florida

Advanced Research Institute, Inc /ID# 265548, New Port Richey, Florida

Hillcrest Medical Research, LLC /ID# 267237, Orange City, Florida

Endoscopic Research, Inc. /ID# 267211, Orlando, Florida

AdventHealth Medical Group - Tampa - Bruce B Downs Boulevard /ID# 265538, Tampa, Florida

Florida Medical Clinic - Zephyrhills /ID# 267392, Zephyrhills, Florida

Gastroenterology Associates of Central Georgia /ID# 265547, Macon, Georgia

Treasure Valley Medical Research /ID# 267114, Boise, Idaho

University of Chicago Medical Center /ID# 267400, Chicago, Illinois

OSF St. Francis Medical Center /ID# 266973, Peoria, Illinois

Springfield Clinic Main Campus /ID# 267434, Springfield, Illinois

University of Kentucky Chandler Medical Center /ID# 265564, Lexington, Kentucky

Metropolitan Gastroenterology Group - Chevy Chase /ID# 265877, Chevy Chase, Maryland

Lucida Clinical Trials /ID# 266548, New Bedford, Massachusetts

Henry Ford Medical Center - Columbus /ID# 266503, Novi, Michigan

Mayo Clinic-Rochester /ID# 265550, Rochester, Minnesota

GI Associates Research, LLC /ID# 267433, Columbia, Missouri

BVL Clinical Research /ID# 265870, Liberty, Missouri

Washington University School of Medicine - St. Louis /ID# 266938, Saint Louis, Missouri

Vector Clinical Trials /ID# 265561, Las Vegas, Nevada

NYU Langone Long Island Clinical Research Association /ID# 265566, Great Neck, New York

Icahn School of Medicine at Mount Sinai /ID# 266857, New York, New York

Northwell Health-Lenox Hill Hospital /ID# 265527, New York, New York

Care Access - Yonkers /ID# 266781, Yonkers, New York

Digestive Health Partners - Biltmore Office /ID# 265539, Asheville, North Carolina

Velocity Clinical Research - Durham /ID# 267712, Durham, North Carolina

University of Cincinnati /ID# 265589, Cincinnati, Ohio

The Ohio State University /ID# 265577, Columbus, Ohio

Digestive Disease Specialists - Oklahoma /ID# 265901, Oklahoma City, Oklahoma

Penn State Health Milton South Hershey Medical Center /ID# 267126, Hershey, Pennsylvania

University of Pennsylvania /ID# 265904, Philadelphia, Pennsylvania

Gastroenterology Associates of Orangeburg /ID# 267548, Orangeburg, South Carolina

GI associates of Northeast Tennessee /ID# 265567, Johnson City, Tennessee

Gi Alliance - Cedar Park /ID# 268153, Cedar Park, Texas

Proactive Clinical Research /ID# 267305, El Paso, Texas

Digestive Health Associates of Texas (DHAT) Research Institute - Garland /ID# 266935, Garland, Texas

Houston Methodist Hospital /ID# 265533, Houston, Texas

Caprock Gastro Research - Lubbock - 80th Street /ID# 265541, Lubbock, Texas

GI Alliance: Mansfield /ID# 266947, Mansfield, Texas

Clinical Associates in Research Therapeutics of America, LLC /ID# 265899, San Antonio, Texas

Sun Research Institute /ID# 266723, San Antonio, Texas

Texas Digestive Disease Consultants - Southlake /ID# 265576, Southlake, Texas

Tyler Research Institute, LLC /ID# 265545, Tyler, Texas

Care Access - Ogden /ID# 266428, Ogden, Utah

Care Access - Salt Lake City /ID# 266785, Salt Lake City, Utah

Washington Gastroenterology - Tacoma /ID# 267302, Tacoma, Washington

Ordensklinikum Linz GmbH Barmherzige Schwestern /ID# 265929, Linz, Oberoesterreich

Klinikum Wels-Grieskirchen GmbH /ID# 266035, Wels, Oberoesterreich

Medizinische Universitaet Graz /ID# 275453, Graz, Steiermark

Medizinische Universitaet Innsbruck /ID# 265930, Innsbruck, Tirol

Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 265928, Salzburg, Not set

Medizinische Universitaet Wien /ID# 265926, Wien, Not set

Imelda Ziekenhuis /ID# 265995, Bonheiden, Antwerpen

Universite Libre de Bruxelles - Hopital Erasme /ID# 265993, Anderlecht, Bruxelles-Capitale

CHU Saint-Pierre /ID# 266431, Brussels, Bruxelles-Capitale

Cliniques Universitaires UCL Saint-Luc /ID# 265521, Bruxelles, Bruxelles-Capitale

Groupe Sante CHC - Clinique du MontLegia /ID# 265522, Liège, Liege

Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant /ID# 265517, Yvoir, Namur

UZ Leuven /ID# 265519, Leuven, Vlaams-Brabant

AZ Groeninge /ID# 265544, Kortrijk, West-Vlaanderen

CHU de Liege /ID# 265542, Liege, Not set

Hospital Tsaritsa Yoanna /ID# 266235, Sofiya, Sofia

Medical Center - Doverie /ID# 267050, Sofiya, Sofia

ACIBADEM City Clinic Diagnostic-Consultative Center /ID# 266239, Sofiya, Sofia

Umbal Kaspela /ID# 266234, Plovdiv, Not set

2nd Mhat /ID# 266238, Sofia, Not set

Acibadem City Clinic Tokuda University Hospital EAD /ID# 267437, Sofia, Not set

Military Medical Academy Multiprofile Hospital /ID# 267051, Sofia, Not set

UMHAT Multiprofile Hospital for Active Treatment Sveta Marina /ID# 266237, Varna, Not set

University of Calgary /ID# 265524, Calgary, Alberta

Gastroenterology and Internal Medicine Research Institute /ID# 265610, Edmonton, Alberta

University of Alberta Hospital /ID# 265614, Edmonton, Alberta

London Health Sciences Centre - University Hospital /ID# 267298, London, Ontario

Toronto Digestive Disease Associates /ID# 267358, Vaughan, Ontario

Diex Recherche Quebec Inc. /ID# 265611, Quebec, Not set

Poliklinika Solmed /ID# 265509, Zagreb, Grad Zagreb

Poliklinika Borzan d.o.o. /ID# 265503, Osijek, Osjecko-baranjska Zupanija

Specialty Hospital Medico /ID# 265504, Rijeka, Primorsko-goranska Zupanija

Klinicki Bolnicki Centar (KBC) Split /ID# 265511, Split, Splitsko-dalmatinska Zupanija

Hepato-Gastroenterologie HK /ID# 265387, Hradec Králové, Hradec Kralove

SurGal Clinic /ID# 265388, Brno, Jihomoravsky Kraj

Iscare Klinické Centrum /ID# 265407, Prague, Praha 9

Medicum /ID# 268304, Tallinn, Harjumaa

East Tallinn Central Hospital /ID# 267658, Tallinn, Not set

Tartu University Hospital /ID# 267656, Tartu, Not set

Chu de Nice-Hopital L'Archet Ii /Id# 267478, Nice, Alpes-Maritimes

Centre Hospitalier Universitaire de Bordeaux /ID# 265721, Pessac CEDEX, Gironde

CHU de Toulouse - Hôpital Rangueil /ID# 267479, Toulouse CEDEX 9, Haute-Garonne

CHU de Montpellier - Hopital Saint Eloi /ID# 265718, Montpellier, Herault

Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou /ID# 266848, Rennes, Ille-et-Vilaine

Centre Hospitalier Universitaire de Saint Etienne - Hopital Nord /ID# 265340, St-Priest-en-Jarez, Loire

CHRU de Nancy-Hopital Brabois Adultes /ID# 265703, Vandoeuvre les Nancy, Lorraine

Hospices Civils de Lyon - Centre Hospitalier Lyon-Sud /ID# 266851, Pierre Benite, Rhone

Clinique Jules Verne /ID# 267480, Nantes, Not set

Hôpital Saint Antoine /ID# 265725, Paris, Not set

Universitaetsklinikum Freiburg /ID# 265755, Freiburg, Baden-Wuerttemberg

Universitaetsmedizin Mannheim /ID# 266961, Mannheim, Baden-Wuerttemberg

Universitaetsklinikum Ulm /ID# 266962, Ulm, Baden-Wuerttemberg

Universitaetsklinikum Erlangen /ID# 265927, Erlangen, Bayern

Markus Krankenhaus /ID# 265938, Frankfurt am Main, Hessen

Universitaetsklinikum Frankfurt /ID# 266827, Frankfurt, Hessen

Klinikum Lueneburg /ID# 266886, Lueneburg, Niedersachsen

St. Marien- und St. Annastiftskrankenhaus /ID# 265912, Ludwigshafen am Rhein, Rheinland-Pfalz

Universitaetsklinikum des Saarlandes /ID# 265753, Homburg, Saarland

Studiengesellschaft BSF Unternehmergesellschaft /ID# 265751, Halle (Saale), Sachsen-Anhalt

Universitaetsklinikum Carl Gustav Carus Dresden /ID# 265931, Dresden, Sachsen

Eugastro /ID# 266826, Leipzig, Sachsen

Universitaetsklinikum Schleswig-Holstein - Campus Kiel /ID# 265738, Kiel, Schleswig-Holstein

Universitaetsklinikum Schleswig-Holstein Campus Luebeck /ID# 267254, Lübeck, Schleswig-Holstein

Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 265752, Berlin, Not set

DRK Kliniken Berlin - Westend /ID# 265925, Berlin, Not set

Krankenhaus Waldfriede /ID# 266676, Berlin, Not set

Debreceni Egyetem-Klinikai Kozpont /ID# 267389, Debrecen, Hajdu-Bihar

Clinfan /ID# 267385, Szekszárd, Tolna

Synexus Hungary Clinical Research Centre - Budapest /ID# 267384, Budapest, Not set

Semmelweis Egyetem /ID# 267064, Budapest, Not set

Semmelweis Egyetem /ID# 267068, Budapest, Not set

Szegedi Tudományegyetem /ID# 267386, Szeged, Not set

Portiuncula University Hospital /ID# 267771, Ballinasloe, Galway

Our Lady of Lourdes Hospital - Drogheda /ID# 267768, Drogheda, Louth

Midland Regional Hospital Mullingar /ID# 267769, Mullingar, Westmeath

St. Vincent's University Hospital /ID# 267766, Dublin, Not set

Beaumont Hospital /ID# 267770, Dublin, Not set

Connolly Hospital /ID# 268021, Dublin, Not set

Soroka Medical Center /ID# 267235, Be'er Sheva, HaDarom

Edith Wolfson Medical Center /ID# 267640, Holon, HaMerkaz

Tel Aviv Sourasky Medical Center /ID# 267307, Tel Aviv, Tel-Aviv

Rambam Health Care Campus /ID# 267641, Haifa, Not set

Azienda Ospedaliero Universitaria di Cagliari - P.O. Duilio Casula /ID# 267287, Monserrato, Cagliari

Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 267143, San Giovanni Rotondo, Foggia

IRCCS Istituto Clinico Humanitas /ID# 265946, Rozzano, Lombardia

IRCCS Ospedale San Raffaele /ID# 265951, Milan, Milano

Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 265935, Rome, Roma

Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 265940, Rome, Roma

A.O. Ordine Mauriziano di Torino /ID# 267144, Turin, Torino

IRCCS Ospedale Sacro Cuore Don Calabria /ID# 265942, Negrar, Verona

Azienda Ospedaliero-Universitaria Renato Dulbecco /ID# 267722, Catanzaro, Not set

Azienda Ospedaliera Universitaria Gaetano Martino /ID# 267145, Messina, Not set

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico /ID# 265949, Milano, Not set

Inje University Haeundae Paik Hospital /ID# 266380, Busan, Busan Gwang Yeogsi

Dong-A University Medical Center /ID# 266709, Busan, Busan Gwang Yeogsi

The Catholic University of Korea, Daejeon St. Mary's Hospital /ID# 265488, Daejeon, Daejeon Gwang Yeogsi

Chungang University Hospital /ID# 266427, Dongjak-gu, Seoul Teugbyeolsi

Samsung Medical Center /ID# 265489, Seoul, Seoul Teugbyeolsi

Kyungpook National University Chilgok Hospital /ID# 265487, Daegu, Not set

Liepaja Regional Hospital /ID# 267703, Liepaja, Not set

Pauls Stradins Clinical University Hospital /ID# 267705, Riga, Not set

Digestive Diseases Center GASTRO /ID# 267707, Riga, Not set

Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 267695, Kaunas, Not set

Panevezys Republican Hospital /ID# 267709, Panevezys, Not set

Vilnius University Hospital Santaros Klinikos /ID# 267711, Vilnius, Not set

Elisabeth TweeSteden Ziekenhuis /ID# 265729, Tilburg, Noord-Brabant

Amsterdam UMC, locatie AMC /ID# 268321, Amsterdam, Noord-Holland

Universitair Medisch Centrum Groningen /ID# 265736, Groningen, Not set

Universitair Medisch Centrum Utrecht /ID# 265731, Utrecht, Not set

Akershus University Hospital /ID# 267642, Lørenskog, Akershus

Helse More- og Romsdal HF, Alesund sjukehus /ID# 267632, Alesund, More Og Romsdal

Oslo Universitetssykehus Ulleval /ID# 267630, Oslo, Not set

NZOZ Centrum Medyczne KERmed /ID# 266766, Bydgoszcz, Kujawsko-pomorskie

Gastromed Sp. z o.o /ID# 266765, Torun, Kujawsko-pomorskie

Malopolskie Centrum Kliniczne /ID# 265943, Krakow, Malopolskie

Medical Network Sp.z.o.o. WIP Warsaw IBD Point Profesor Kierkus /ID# 266764, Warsaw, Mazowieckie

Bodyclinic Sp. z o.o. sp.k. /ID# 265945, Warszawa, Mazowieckie

Endoskopia Sp. z.o.o. /ID# 265934, Sopot, Pomorskie

H-T Centrum Medyczne Endoterapia /ID# 265937, Tychy, Slaskie

Polimedica PTG Kielce /ID# 267066, Kielce, Swietokrzyskie

Unidade Local de Saude do Alto Ave, EPE /ID# 265892, Guimaraes, Braga

2CA-Braga, Hospital de Braga /ID# 265894, Braga, Not set

Unidade Local de Saude de Coimbra, EPE /ID# 267240, Coimbra, Not set

Unidade Local de Saude de Lisboa Ocidental, EPE /ID# 267242, Lisboa, Not set

Unidade Local de Saude de Santa Maria, EPE /ID# 266113, Lisboa, Not set

Unidade Local de Saude do Alto Minho, EPE - Hospital de Santa Luzia /ID# 265885, Viana Do Castelo, Not set

Memorial Healthcare International S.R.L. /Id# 267328, Bucharest, Bucuresti

Spitalul Clinic Colentina /ID# 267208, Bucharest, Bucuresti

Clinica Gastro Med SRL /ID# 267204, Cluj-Napoca, Cluj

OncoHelp Association /ID# 267203, Timișoara, Timis

Clinical Hospital Center Zvezdara /ID# 265605, Belgrade, Beograd

Military Medical Academy /ID# 267452, Belgrade, Beograd

University Clinical Hospital Center "Dr. Dragisa Misovic - Dedinje" /ID# 265607, Belgrade, Beograd

Clinical Hospital Center - Bežanijska Kosa /ID# 265604, Belgrade, Beograd

Leskovac General Hospital /ID# 265606, Leskovac, Jablanicki Okrug

General Hospital Djordje Joanovic /ID# 266040, Zrenjanin, Vojvodina

University Clinical Center Vojvodina /ID# 265603, Novi Sad, Not set

Mount Elizabeth Hospital /ID# 268354, Singapore, Central Singapore

Gleneagles Hospital /ID# 268385, Singapore, Central Singapore

National University Hospital /ID# 268128, Singapore, Not set

Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 266064, Banska Bystrica, Banskobystricky Kraj

KM Management, spol. s.r.o. /ID# 266070, Nitra, Nitriansky Kraj

Gastro I., s.r.o. /ID# 267159, Prešov, Presovsky Kraj

ENDOMED s.r.o /ID# 266068, Košice, Not set

General Hospital Celje /ID# 267699, Celje, Not set

University Medical Centre Ljubljana /ID# 267697, Ljubljana, Not set

Complejo Hospitalario Universitario de Santiago (CHUS) /ID# 266902, Santiago de Compostela, A Coruna

Hospital Universitario Virgen Macarena /ID# 266648, Seville, Sevilla

Hospital Universitario Virgen del Rocio /ID# 266727, Seville, Sevilla

Hospital Clinic de Barcelona /ID# 265415, Barcelona, Not set

Hospital Universitario 12 de Octubre /ID# 265444, Madrid, Not set

Hospital Universitario La Paz /ID# 265412, Madrid, Not set

Hospital Alvaro Cunqueiro /ID# 266647, Pontevedra, Not set

Hospital Universitari i Politècnic La Fe /ID# 265478, Valencia, Not set

Intesto /ID# 265728, Bern, Not set

Western General Hospital - NHS Lothian /ID# 266333, Edinburgh, Edinburgh, City Of

Gartnavel General Hospital /ID# 266407, Glasgow, Glasgow City

Royal Free Hospital /ID# 268065, London, Greater London

Guy's Hospital /ID# 266336, London, Greater London

St George's University Hospitals NHS Foundation Trust /ID# 266335, London, Greater London

The John Radcliffe Hospital /ID# 266334, Oxford, Oxfordshire

The Royal Wolverhampton NHS Trust /ID# 268158, Guildford, Surrey

University Hospital Coventry & Warwickshire NHS Trust /ID# 267128, Coventry, Warwickshire

Barts Health NHS Trust /ID# 266410, London, Not set

Royal Victoria Infirmary /ID# 268064, Newcastle upon Tyne, Not set

Conditions: Crohn's Disease

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Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)

NCT05605093

Recruiting

Treatments are needed to improve outcomes among patients hospitalized for COVID-19, including direct-acting antiviral (DAA) agents to mitigate the pathology driven by ongoing viral replication. This trial will evaluate S-217622 (ensitrelvir), an anti-SARS-CoV2 3C-like protease inhibitor (PI) developed by Shionogi \&; Co. Ltd. The study design is a randomized, placebo-controlled, multi-center international clinical trial that will evaluate the clinical efficacy of ensitrelvir when given in addit... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: University of Alabama Birmingham University Hospital (Site 213-002), Birmingham, Alabama +186 locations

University of Alabama Birmingham University Hospital (Site 213-002), Birmingham, Alabama

Banner University Medical Center Tucson (Site 206-004), Tucson, Arizona

Southern Arizona VA Healthcare System (Site 074-009), Tucson, Arizona

UCSF Fresno (Site 203-005), Fresno, California

VA Loma Linda Healthcare System (Site 074-017), Loma Linda, California

MemorialCare Health System (Site 066-003, Long Beach, California

VA Long Beach Healthcare System (Site 074-026), Long Beach, California

Cedars-Sinai Medical Center (Site 208-002), Los Angeles, California

Ronald Reagan UCLA Medical Center (Site 203-002), Los Angeles, California

VA Northern California Health Care System (Site 074-023), Mather, California

Hoag Memorial Hospital Presbyterian (Site 080-026), Newport Beach, California

Veterans Affairs Palo Alto Health Care System (VAPAHCS) (Site 074-005), Palo Alto, California

UC Davis Health (Site 203-004), Sacramento, California

VA San Diego Healthcare System (Site 074-016), San Diego, California

Zuckerberg San Francisco General Hospital and Trauma Center (Site 213-007), San Francisco, California

UCSF Medical Center at Mount Zion (203-007), San Francisco, California

San Francisco VAMC (Site 074-002), San Francisco, California

University of California San Francisco (Site 203-001), San Francisco, California

Stanford University Hospital & Clinics (Site 203-003), Stanford, California

Lundquist Institute for Biomedical Innovation (Site 066-002), Torrance, California

Rocky Mountain Regional VA Medical Center (Site 074-010), Aurora, Colorado

University of Colorado Hospital (Site 204-001), Aurora, Colorado

Public Health Institute at Denver Health (Site 017-004), Denver, Colorado

Yale University (Site 025-001), New Haven, Connecticut

MedStar Health Research Institute/MedStar Washington Hospital Center (Site 009-021), Washington, District of Columbia

Washington DC VA Medical Center (Site 009-004), Washington, District of Columbia

University of Florida - Gainesville (Site 201-004), Gainesville, Florida

Miami VA Healthcare System (Site 074-003), Miami, Florida

Orlando VA Medical Center (Site 074-032), Orlando, Florida

Tampa General Hospital (032-001), Tampa, Florida

John H. Stroger, Jr. Hospital of Cook County (Site 080-046), Chicago, Illinois

University of Illinois at Chicago (Site 008-012), Chicago, Illinois

Carle Foundation Hospital (Site 080-049), Urbana, Illinois

Lutheran Medical Group (Site 301-010), Fort Wayne, Indiana

The University of Kansas Hospital (Site 080-044), Kansas City, Kansas

University of Kentucky (Site 210-004), Lexington, Kentucky

NIH Clinical Center (Site 080-043), Bethesda, Maryland

Massachusetts General Hospital (202-002), Boston, Massachusetts

Beth Israel Deaconess Medical Center (Site 202-001), Boston, Massachusetts

Baystate Medical Center (Site 201-001), Springfield, Massachusetts

UMass Chan Medical School (Site 080-007), Worcester, Massachusetts

VA Ann Arbor Healthcare System (Site 074-028), Ann Arbor, Michigan

Henry Ford Health System (Site 014-001), Detroit, Michigan

Sinai-Grace Hospital (Site 205-005), Detroit, Michigan

Hennepin Healthcare Research Institute (Site 027-001), Minneapolis, Minnesota

M Health Fairview University of Minnesota Medical Center (Site 112-001), Minneapolis, Minnesota

University of Minnesota, Minneapolis, Minnesota

Mayo Clinic (Site 054-001), Rochester, Minnesota

University of Mississippi Medical Center (Site 202-005), Jackson, Mississippi

Washington University School of Medicine (Site 003-001), Saint Louis, Missouri

University of Nebraska Medical Center (Site 080-045), Omaha, Nebraska

Dartmouth-Hitchcock Medical Center (301-024), Lebanon, New Hampshire

Cooper University Hospital (Site 019-001), Camden, New Jersey

Hackensack Meridian Health (Site 301-030), Hackensack, New Jersey

New Jersey Medical School Clinical Research Center (028-001), Newark, New Jersey

University of New Mexico Hospital (Site 213-008), Albuquerque, New Mexico

CHRISTUS - St. Vincent (Site 080-051), Santa Fe, New Mexico

Lincoln Medical Center (Site 003-016), Bronx, New York

Montefiore Medical Center - Moses Hospital (Site 206-001), Bronx, New York

Montefiore Medical Center - Weiler campus (Site 206-003), Bronx, New York

James J. Peters VAMC (Site 023-003), Bronx, New York

NYU Brooklyn (301-033), Brooklyn, New York

New York Presbyterian Queens (003-005), Flushing, New York

Mount Sinai Queens (Site 081-105), Long Island City, New York

NYU Long Island (301-034), Mineola, New York

New York University Tisch Hospital (Site 301-013), New York, New York

Mount Sinai Medical Center (Site 301-012), New York, New York

NYC Health + Hospital Harlem (Site 003-003), New York, New York

Weill Cornell Clinical Research Unit (065-001), New York, New York

St. Lawrence Health System (Site 301-029), Potsdam, New York

Duke University Hospital (Site 301-006), Durham, North Carolina

Wake Forest Baptist Health (Site 210-001), Winston-Salem, North Carolina

University of Cincinnati Medical Center (Site 207-003), Cincinnati, Ohio

Cleveland Clinic Foundation (Site 207-001), Cleveland, Ohio

Ohio State University Wexner Medical Center (Site 207-004), Columbus, Ohio

Portland VA Health Care System (074-024), Portland, Oregon

Penn State Health Milton S. Hershey Medical Center (Site 209-002), Hershey, Pennsylvania

Rhode Island Hospital (Site 080-036), Providence, Rhode Island

The Miriam Hospital (Site 080-039), Providence, Rhode Island

Kent County Memorial Hospital (080-048), Warwick, Rhode Island

Ralph H. Johnson VA Medical Center (Site 074-015), Charleston, South Carolina

Medical University of South Carolina (Site 210-002), Charleston, South Carolina

Monument Health Rapid City Hospital (Site 213-005), Rapid City, South Dakota

Vanderbilt University Medical Center (Site 212-001), Nashville, Tennessee

Hendrick Medical Center (Site 080-014), Abilene, Texas

CHRISTUS Spohn Shoreline Hospital (Site 080-001), Corpus Christi, Texas

Baylor, Scott and White Health (301-003), Dallas, Texas

Parkland Health and Hospital Systems (Site 084-002), Dallas, Texas

UT Southwestern Medical Center (Site 084-001), Dallas, Texas

Houston Methodist Hospital (Site 301-028), Houston, Texas

MEDVAMC (Site 074-006), Houston, Texas

University of Texas Health Science Center (Site 203-006), Houston, Texas

CHRISTUS Good Shepherd Medical Center (Site 080-031), Longview, Texas

UT Health San Antonio (Site 009-022), San Antonio, Texas

Intermountain Medical Center (Site 211-001), Murray, Utah

University of Utah Health (Site 211-002), Salt Lake City, Utah

University of Virginia Health System, University Hospital (Site 210-003), Charlottesville, Virginia

Salem VA Medical Center (Site 074-014), Salem, Virginia

Harborview Medical Center (208-001), Seattle, Washington

Providence (Sacred Heart) (Site 213-004), Spokane, Washington

West Virginia University Medicine (301-023), Morgantown, West Virginia

William S. Middleton Memorial Veterans Hospital (074-030), Madison, Wisconsin

Froedtert Memorial Lutheran Hospital (052-001), Milwaukee, Wisconsin

Instituto Medico Platense (Site 611-025), La Plata, Buenos Aires

Sanatorio Allende (Site 611-030), Córdoba, Cordoba

Clínica Central S.A. (611-028), Villa Regina, Rio Negro

Sanatorio Británico S.A. (611-027), Rosario, Santa Fe

CEMIC (Site 611-021), Buenos Aires, Not set

Hospital Rawson (Site 611-012), Cordoba, Not set

Sanatorio Medico de Diagnostico y Tratamiento (611-029), Santa Fe, Not set

South Western Sydney Local Health District, Liverpool (Site 612-063), Liverpool, New South Wales

St. Vincent's Hospital (Site 612-002), Sydney, New South Wales

Westmead Hospital (Site 612-058), Westmead, New South Wales

Austin Health (612-020), Heidelberg, Victoria

The Alfred Hospital (Site 612-017), Melbourne, Victoria

Fundação Universidade Caxias do Sul Hospital Geral (649-218), Caxias Do Sul, RS

Hospital de Clínicas de Porto Alegre (649-101), Porto Alegre, RS

Sociedade Literária e Caritativa Santo Agostinho - Hospital São José (Site 649-204), Criciuma, SC

Hospital Nereu Ramos (Site 649-210), Florianopolis, SC

Unimed Joinville Cooperativa de Trabalho Médico (Site 649-202), Joinville, SC

Associação Beneficente Hospital Universitário - Universidade de Marília (Site 649-212), Marília, SP

Instituto de Infectologia Emílio Ribas - IIER (Site 649-001), Sao Paulo, SP

Real e Benemérita Associação Portuguesa de Beneficência de São Paulo (Site 649-201, Sao Paulo, SP

Associação Beneficente Síria - HCor (Site 649-203), Sao Paulo, SP

Sociedade Beneficente de Senhoras Hospital Sirio-Libanês (Site 649-217), Sao Paulo, SP

Hospital Alemão Oswaldo Cruz (649-215), São Paulo, SP

Hospital SEPACO (649-207), São Paulo, SP

Aarhus Universitetshospital, Skejby (625-002), Aarhus, N

Aalborg Hospital (Site 625-005), Aalborg, Not set

Rigshospitalet, CHIP (Site 625-006), Copenhagen, Not set

Bispebjerg Hospital (Site 625-013), Copenhagen, Not set

Herlev/Gentofte Hospital (Site 625-012), Hellerup, Not set

Nordsjaellands Hospital, Hillerod (Site 625-009), Hillerød, Not set

Hvidovre University Hospital, Department of Infections Diseases (Site 625-001), Hvidovre, Not set

Kolding Sygehus, Medicinsk Afdeling (Site 625-011), Kolding, Not set

Odense University Hospital (Site 625-004), Odense, Not set

Zealand University Hospital Roskilde (Site 625-010), Roskilde, Not set

AIDS and Clinical Immunology Research Center (Site 627-201), Tbilisi, Not set

Universitätsklinikum Bonn, Medizinische Klinik I, Immunologische Ambulanz (622-010), Bonn, Not set

Klinik I für Innere Medizin der Universität zu Köln (Site 622-008), Cologne, Not set

Johann Wolfgang Goethe Univ. Hosp., Infektionsambulanz CRS (622-001), Frankfurt, Not set

Dept of Critical Care and Pulmonary Medicine, Evangelismos General Hospital (635-020), Athens, Attica

1st Respiratory Medicine Dept, Athens University Medical School (635-015), Athens, Attica

3rd Dept of Medicine, Medical School (635-022), Athens, Attica

Attikon University General Hospital (Site 635-009), Athens, Attica

Democritus University of Thrace (635-021), Alexandroupolis, Evros

Fujita Health University Hospital (Site 612-105), Toyoake, Aichi

Center Hospital of the National Center for Global Health and Medicine (Site 612-101), Shinjuku-Ku, Tokyo

Rinku General Medical Center (Site 612-107), Osaka, Not set

Seoul National University Bundang Hospital (Site 612-904), Seongnam, Gyeonggi

Seoul St. Mary's Hospital (Site 612-903), Seocho, Seoul

Asan Medical Center (612-901), Seoul, Not set

Chung-Ang University Hospital (Site 612-902), Seoul, Not set

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran (Site 653-001), Mexico City, Cdmx

Instituto Nacional de Enfermedades Respiratorias Ismael Cosió Villegas (Site 653-002), Mexico City, Cdmx

Hospital General Dr. Aurelio Valdivieso (Site 653-004), Oaxaca City, OA

Institute of Human Virology-Nigeria (IHVN) (Site 612-601), Abuja, FCT

Hospital Nacional Hipolito Unanue (651-008), Lima, Not set

Hospital Nacional Sergio E. Bernales (651-007), Lima, Not set

Wojewodzki Szpital Zakazny (Site 625-302), Warsaw, Not set

VA Caribbean Health Care (074-033), San Juan, Not set

Tan Tock Seng Hospital (Site 612-201), Singapore, Not set

Durban International Clinical Research Site (WWH) (652-005), Durban, KwaZulu-Natal

Greys Hospital (080-202), Pietermaritzburg, KwaZulu-Natal

University of Cape Town (UCT) Lung Institute (Site 080-201), Cape Town, Western Cape

Hospital Universitari Germans Trias i Pujol (626-003), Badalona, Barcelona

Hospital del Mar (626-025), Barcelona, Not set

Hospital Universitari Vall d'Hebron (Site 626-033), Barcelona, Not set

Hospital Clinic de Barcelona (626-004), Barcelona, Not set

Hospital General Universitario Gregorio Marañón (Site 626-001), Madrid, Not set

Hospital Clínico San Carlos (Site 626-017), Madrid, Not set

Hospital Universitario La Paz (Site 626-012), Madrid, Not set

University Hospital Zurich (Site 621-201), Zurich, Not set

Chulalongkorn University and The HIV-NAT (Site 613-001), Bangkok, Not set

Khon Kaen University, Srinagarind Hospital (Site 613-003), Khon Kaen, Not set

MRC/UVRI & LSHTM Uganda Research Unit (634-601), Entebbe, Not set

Gulu Regional Referral Hospital (634-603), Gulu, Not set

St. Francis Hospital, Nsambya (Site 634-607), Kampala, Not set

Lira Regional Referral Hospital (634-605), Lira, Not set

Masaka Regional Referral Hospital (634-606), Masaka, Not set

Central City Clinical Hospital of Ivano-Frankivsk City Council (Site 627-302), Ivano-Frankivs'k, Not set

Treatment and Diagnostic Center ADONIS Plus (627-304), Kyiv, Not set

Hospital #1 of Zhytomyr City Council (627-303), Zhytomyr, Not set

Royal Free Hospital (634-006), London, Not set

Guy's & St. Thomas' NHS Foundation Trust (Site 634-011), London, Not set

Royal Victoria Infirmary (Site 634-007), Newcastle Upon Tyne, Not set

Parirenyatwa General Hospital (Site 634-901), Harare, Not set

Conditions: COVID-19

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Outpatient Treatment With Anti-Coronavirus Immunoglobulin

NCT04910269

Recruiting

The primary objective of the Outpatient Treatment with Anti-Coronavirus Immunoglobulin (OTAC) (INSIGHT 012) trial is to compare the safety and efficacy of a single infusion of anti-COVID-19 hyperimmune intravenous immunoglobulin (hIVIG) versus placebo among adults with recently diagnosed severe acute respiratory syndrome - coronavirus 2 (SARS-CoV2) infection who do not require hospitalization. The primary endpoint of this double-blind randomized trial is a five-category ordinal outcome that asse... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Southern Arizona VA Healthcare System (074-009), Tucson, Arizona +61 locations

Southern Arizona VA Healthcare System (074-009), Tucson, Arizona

VA Northern California Health Care System (074-023), Mather, California

Stanford University Hospital & Clinics (Site 203-003), Palo Alto, California

San Francisco VAMC (Site 074-002), San Francisco, California

Rocky Mountain Regional VA Medical Center (074-010), Aurora, Colorado

MedStar Health Research Institute, Washington, District of Columbia

Washington DC Veterans Affairs Medical Center, Washington, District of Columbia

University of Maryland Medical System, Baltimore, Maryland

Henry Ford Health System Site (014-001), Detroit, Michigan

Infusion Associates, Grand Rapids, Michigan

Mount Sinai Beth Israel Hospital, New York, New York

Icahn School of Medicine at Mount Sinai, New York, New York

Cleveland Clinic Foundation (Site 207-001), Cleveland, Ohio

Penn State Health Milton S. Hershey Medical Center (209-002), Hershey, Pennsylvania

Hendrick Medical Center, Abilene, Texas

CHRISTUS Spohn Shoreline Hospital, Corpus Christi, Texas

UT Southwestern Medical Center, Dallas, Texas

Intermountain Medical Center (211-001), Murray, Utah

Carilion Medical Center (Site 080-018), Roanoke, Virginia

Salem VA Medical Center (074-014), Salem, Virginia

Swedish Hospital First Hill, Seattle, Washington

Instituto Medico Platense, La Plata, Buenos Aires

Centro de Investigaciones Medicas de Mar del Plata (Site 611-031), Mar del Plata, Buenos Aires

Hospital General de Agudos JM Ramos Mejia, Buenos Aires, Not set

St. Vincent's Hospital, Sydney, New South Wales

Odense University Hospital, Odense, C

Aarhus Universitetshospital, Skejby, Aarhus, N

Department of Infectious Diseases, Aalborg, Not set

Rigshospitalet, CHIP, Copenhagen, Not set

Bispebjerg Hospital, Copenhagen, Not set

Herlev/Gentofte Hospital, Hellerup, Not set

Hvidovre University Hospital, Department of Infectious Diseases, Hvidovre, Not set

Kolding Sygehus, Kolding, Not set

Dept of Critical Care and Pulmonary Medicine, Evangelismos General Hospital, Athens, Attica

3rd Dept of Medicine, Medical School, Athens, Attica

Laiko Athens General Hospital, Athens, Attica

Department of Clinical Therapeutics of Alexandra Hospital, Athens, Attica

4th Department of Internal Medicine, Athens, Attica

All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan

Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Not set

Hospital General Dr. Manuel Gea Gonzáles, Mexico City, Cdmx

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Cdmx

Instituto Nacional de Enfermedades Respiratorias Ismael Cosió Villegas, Mexico City, Cdmx

CHRISTUS Centro de Excelencia en Investigacion (Obispado), Monterrey, NL

Hospital General Dr. Aurelio Valdivieso, Oaxaca City, OA

Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona

CAP Can Bou, Castelldefels, Barcelona

CAP El Maresme, Mataro, Barcelona

CAP Corbera, Barcelona, Not set

Siriraj Hospital (Site 613-002), Bangkok Noi, Bangkok

Chulalongkorn University and The HIV-NAT, Pathum Wan, Bangkok

Khon Kaen University, Srinagarind Hospital (Site 613-003), Khon Kaen, Not set

Bamrasnaradura Infections Diseases Institute (613-007), Nonthaburi, Not set

MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Not set

Joint Clinical Research Center (JCRC), Kampala, Not set

Makerere University Lung Institute (Site 634-604), Kampala, Not set

St. Francis Hospital, Nsambya, Kampala, Not set

Lira Regional Referral Hospital, Lira, Not set

Masaka Regional Referral Hospital, Masaka, Not set

Central City Clinical Hospital of Ivano-Frankivsk City Council, Ivano-Frankivs'k, Not set

University College London Hospitals, London, Not set

Royal Victoria Infirmary, Newcastle upon Tyne, Not set

Conditions: COVID, SARS-CoV2 Infection, Covid19

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A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

NCT04576156

Recruiting

The purpose of the study is to evaluate the overall survival of participants treated with imetelstat compared to best available therapy with intermediate-2 or high-risk Myelofibrosis (MF) who are relapsed/refractory (R/R) to Janus Kinase (JAK)-Inhibitor treatment.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: University of California-San Diego/Moores UCSD Cancer Center, La Jolla, California +220 locations

University of California-San Diego/Moores UCSD Cancer Center, La Jolla, California

MemorialCare, Long Beach, California

Cancer and Blood Research Center, Los Alamitos, California

UCLA David Geffen School of Medicine, Los Angeles, California

Smilow Cancer Center at YNHH, New Haven, Connecticut

Clermont Oncology, Clermont, Florida

BRCR Medical Center Inc, Plantation, Florida

University of South Florida, Tampa, Florida

Hawaii Cancer Care, 'Aiea, Hawaii

Fort Wayne Medical Oncology and Hematology, Fort Wayne, Indiana

Goshen Center for Cancer Care, Goshen, Indiana

Norton Cancer Institute, Louisville, Kentucky

Our Lady of the Lake Cancer Institute, Baton Rouge, Louisiana

ONCare Alliance - Pontchartrain, Covington, Louisiana

Ochsner Clinic Foundation, New Orleans, Louisiana

Maryland Oncology Hematology, Rockville, Maryland

Mosaic Life Care, Saint Joseph, Missouri

Mercy Health, Saint Louis, Missouri

Oncology Hematology Associates, Springfield, Missouri

Nebraska Cancer Specialists, Omaha, Nebraska

Cancer Care Specialists of Reno, Reno, Nevada

Hematology-Oncology Associates of Central New York (HOACNY), East Syracuse, New York

Icahn School of Medicine at Mount Sinai, New York, New York

Duke University Medical Center, Durham, North Carolina

Gabrail Cancer Center, Canton, Ohio

Ohio Health, Columbus, Ohio

Taylor Cancer Research Center, Maumee, Ohio

Oregon Oncology Specialists, Salem, Oregon

Cancer Care Associates of York, York, Pennsylvania

Sanford Health, Sioux Falls, South Dakota

Avera Cancer Institute, Sioux Falls, South Dakota

Prairie Lakes Health Care System, Inc., Watertown, South Dakota

Oncology Consultants, Houston, Texas

The University of Texas MD, Houston, Texas

Community Cancer Trials of Utah, Ogden, Utah

Utah Cancer Specialists, Salt Lake City, Utah

Hematology Oncology Associates of Fredericksburg, Fredericksburg, Virginia

Northwest Medical Specialties PLLC, Tacoma, Washington

Northwest Specialits, Tacoma, Washington

Hospital Aleman, Ciudad de Buenos Aires, Buenos Aires

Sanatorio de la Mujer, Rosario, Santa Fe

Sanatorio Allende, Córdoba, Not set

Royal North Shore Hospital, St Leonards, New South Wales

Royal Brisbane and Women's Hospital, Herston, Queensland

Royal Hobart Hospital, Hobart, Tasmania

Epworth Healthcare, Richmond, Victoria

Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel, Wein, Burgenland

Krankenhaus der Elisabethinen, Linz, Oberösterreich

Kepler Universitätsklinikum Gm, Linz, Oberösterreich

Klinikum Wels-Grieskirchen GmbH, Wels, Oberösterreich

UZ Antwerpen, Edegem, Antwerpen

Centre Hospitalier de Jolimont, Haine-Saint-Paul, Hainaut

CHU De Liège, Liege, Liège

Universitair Ziekenhuis Gent, Gent, Oost-Vlaanderen

Zna - Campus Middelheim, Antwerpen, Not set

ZNA Stuyvenberg Antwerpen, Antwerpen, Not set

AZ Klina, Antwerpen, Not set

Universitair Ziekenhuis Brussel - Myeloom Centrum Brussel (MCB), Jette, Not set

Centro de oncologia Leonardo da Vinci, Fortaleza, Ceará

Hospital das Clínicas UFG, Goiânia, Goiás

Hospital Erasto Gaertner, Curitiba, Paraná

Hospital de Clinicas de Porto Alegre - UFRGS, Porto Alegre, Rio Grande Do Sul

Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa LTDA, Porto Alegre, Rio Grande Do Sul

CEPON Centro de Pesquisas Oncologicas SC, Florianópolis, Not set

Instituto de Educação, Pesquisa e Gestão em Saúde, São Paulo, Not set

Hospital Israelita Albert Einstein, São Paulo, Not set

Fundacao Doutor Amaral Carvalho / Hospital Amaral Carvalho, São Paulo, Not set

Hospital A.C.Camargo Cancer Center - Clinical Oncology, São Paulo, Not set

UMHAT "Dr. Georgi Stranski", Pleven, Not set

UMBAL Sveti Georgi, Plovdiv, Not set

Specialized Hospital for Active Therapy of Hematological dis, Sofia, Not set

Oncologos del Occidente S.A, Pereira, Risaralda

Hospital Pablo Tobon Uribe, Antioquia, Not set

Centro Medico Imbanaco de Cali S.A., Cali, Not set

FOSCAL, Floridablanca, Not set

Odense University Hospital - Hematology, Odense, Not set

Institut de cancérologie du Gard - Hematologie clinique, Nimes Cedex 09, Gard

CHU Bretonneau, Tours, Indre-et-Loire

Hopital Bicetre, Paris, Le Kremlin-Bicêtre

CHU de Limoges Dupuytren, Haute-Vienne, Limoges

CHU de Nice - Hopital de l'Archet II - Pharmacie, Nice, Nice Cedex 3

Hospital CENTRE HOSPITALIER AVIGNON, Avignon cedex, Provence-Alpes-Côte-d'Azur

Centre Hospitalier Lyon, Pierre-benite, Rhône-Alpes

CHU de Saint Etienne, Loire, Saint Priest En Jarez

Centre Hospitalier Du Mans - Cancérologie Médicale, Le Mans, Sarthe

CHRU Brest - Hôpital Morvan, Brest cedex, Not set

CHU - HÃ´pital Saint Louis - Centre D'Investigations Cliniq, Paris, Not set

Hopital Cochin - Aphp Hôpitaux Universitaires Paris Centre, Paris, Île-de-France

LTD Israeli-Georgian Medical R, Tbilisi, Not set

M.Zodelava Hematology Center L, Tbilisi, Not set

J.S.C."K.Eristavi National Cen, Tbilisi, Not set

Multi Profile Clinic Consilium, Tbilisi, Not set

Ltd "Medinvest - Institute of Hematology and Trans, Tbilisi, Not set

Universitätsklinikum Mannheim - University of Heidelberg, Mannheim, Baden-Württemberg

Universitätsklinikum Tübingen, Tübingen, Baden-Württemberg

Universitätsklinikum Carl Gust, Dresden, Hamburg

Klinikum Kempten-Oberallgaeu GmbH, Kempten, Rheinland-Pfalz

Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Sachsen-Anhalt

Universitätsklinikum Leipzig AöR, Leipzig, Sachsen

Universitätsklinikum Schleswig, Kiel, Schleswig-Holstein

Semmelweis Egyetem - III. sz., Budapest, Not set

Dél-pesti Centrumkórház Ország, Budapest, Not set

Szabolcs-Szatmár-Bereg Megyei Önkormányzat Jósa András, Nyíregyháza, Not set

Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz -, Székesfehérvár, Not set

All India Institute of Medical Sciences, Dept. of Hematology, New Delhi (All India Institute Of Medical Sciences), New Delhi, Delhi

Sir Ganga Ram Hospital, New Delhi, Delhi

Nirmal Hospital - Hematology, Surat, Gujarat

St. John's Medical College Hospital, Bangalore, Karnataka

Fortis Hospital 154/9, Bengaluru, Karnataka

Fortis Memorial Research Institute, Gurgaon, New Delhi

All India Institute of Medical Sciences, Bhubaneswar, Orissa

Nilratan Sircar Medical College, Kolkata, West Bengal

Narayana Hrudayalaya Hospital, Hyderabad, Not set

Deenanath Mangeshkar Hospital & Research Center, Pune, Not set

Sahyadri Specialty Hospital, Pune, Not set

Assuta Ashdod University Hospi, Ashdod, HaDarom

Barzilai Medical Center, Ashkelon, HaDarom

Kaplan Medical Center, Rehovot, HaMerkaz

Shamir Medical Center (Assaf Harofeh), Zerifin, HaMerkaz

Western Galilee Hospital - Nahariya, Nahariya, HaZafon

Tel Aviv Sourasky Medical Cent, Tel Aviv, Tel-Aviv

Hadassah Medical Organization, Jerusalem, Yerushalayim

Soroka Medical Center - Hematology Institute, Beersheba, Not set

Bnai Zion Medical Center, Haifa, Not set

Carmel MC, Haifa, Not set

Arcispedale S.Anna - Ematologi, Cona, Ferrara

Istituto Clinico Humanitas Roz, Rozzano, Milano

AOU San Luigi Gonzaga, Orbassano, Torino

PO Civile SS.Antonio e Biagio, Alessandria, Not set

A.O.di Bologna Policl.S.Orsola, Bologna, Not set

Presidio Ospedaliero Garibaldi, Catania, Not set

AOU Careggi, Firenze, Not set

IRCCS Ospedale Policlinico San Martino, Genova, Not set

Clinica Ematologica, Univ. Deg, Genova, Not set

Irccs Irst, Meldola, Not set

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Not set

Ospedale San Raffaele, Milano, Not set

ASST Grande Ospedale Metropoli, Milano, Not set

Azienda Ospedaliera San Gerard, Monza, Not set

AOU Federico II, Napoli, Not set

Ospedale Civile S.Maria delle Croci, AUSL Ravenna, Ravenna, Not set

Arcispedale S Maria Nuova, AO di Reggio Emilia, Reggio Calabria, Not set

Azienda Ospedaliera Bianchi-Me, Reggio Calabria, Not set

AUSL di Rimini Ospedale Infermi di Rimini, Rimini, Not set

ASL Roma 2 - PO "S. Eugenio", Roma, Not set

Policlinico Universitario Agostino Gemelli, Roma, Not set

AOU Città della Salute e della Scienza di Torino, Torino, Not set

Ospedale di Circolo, PO Varese, Varese, Not set

Ospedale S.Bortolo, AULSS n.6, Vicenza, Not set

Inje University Busan Paik Hos, Busan, Busan Gwang'yeogsi [Pusan-Kwangyokshi]

Inje University Haeundae Paik Hospital, Busan, Busan Gwang'yeogsi [Pusan-Kwangyokshi]

Kyungpook National University Hospital - Hematolog, Daegu, Daegu Gwang'yeogsi [Taegu-Kwan]

National Cancer Institute Center for Cancer Research, Goyang-Si, Gyeonggido

Gachon University Gil Medical Center, Incheon, Incheon Gwang'yeogsi [Inch'n-Kwangyokshi]

Korea University Anam Hospital, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi]

Gangnam Severance Hospital, Yonsei University Health System, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi]

Korea University Guro Hospital, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi]

Samsung Medical Center, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi]

Seoul National University Hospital - Department of Internal, Seoul, Seoul Teugbyeolsi [Seoul-T'ukp

Pusan National University Hospital - Hematology and Oncology, Busan, Not set

The Catholic University of Korea, Seongdong, Not set

Severance Hospital, Yonsei Uni, Seoul, Not set

Hospital Pulau Pinang, Pulau Pinang, Georgetown

Hospital Sultanah Aminah Johor Bahru, Johor Bahru, Johor

Hospital Raja Perempuan Zainab II, Kota Bharu, Kelantan

Sarawak General Hospital, Kuching, Sarawak

Hospital Ampang, Ampang, Selangor

Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka w Sl, Slupsk, Pomorskie

Ars Medical Sp. z o.o., Piła, Wielkopolskie

Centrum Medyczne Pratia Poznan, Skorzewo, Wielkopolskie

Wojewodzki Szpital Specjalistyczny, Biała Podlaska, Not set

Pratia Onkologia Katowice, Katowice, Śląskie

CCA-Braga. Centro Clínico Académico - Hospital Braga, Braga, Not set

CHUC - Centro Hospitalar e Universitário de Coimbr, Coimbra, Not set

Instituto Português de Oncologia de Lisboa, Lisboa, Not set

Centro Clinico Fundacao Champalimaud, Lisboa, Not set

H. São Francisco Xavier-Centro, Lisboa, Not set

H. Santa Maria. Centro Hospita, Lisboa, Not set

MONIKI - Oncology, Moscow, Moskovskaya Oblast'

MUZ City Clinical Hospital # 2, Novosibirsk, Novosibirskaya Oblast'

Tula Regional Clinical Hospital, Tula, Tul'skaya Oblast'

Budgetary Healthcare Institution of Omsk Region, Omsk, Not set

V.A. Almazov National Medical Research Center, Saint Petersburg, Not set

First Saint-Petersburg State Medical University n., Saint-Petersburg, Not set

GOU VPO Saratov State Medical University n.a. V.I., Saratov, Not set

National University Cancer Institute (NCIS), Singapore, Central Singapore

Singapore General Hospital, Singapore, Central Singapore

Institut Català d'Oncologia-Ho, Badalona, Barcelona

C.S. Parc Tauli, Sabadell, Barcelona

Hospital Universitario de Gran, Las Palmas de Gran Canaria, Canarias

H. Comarcal Costa del Sol, Málaga, Marbella

H.U. Ribera de Alzira, Alzira, Valencia

H.G.U. Alicante, Alicante, Not set

H. San Pedro de Alcántara, Cáceres, Not set

ICO-Hospital Universitari de G, Girona, Not set

Hospital Universitario Virgen, Granada, Not set

Hospital Universitario Fundaci, Madrid, Not set

Hospital U. 12 Octubre, Madrid, Not set

H.U. La Paz, Madrid, Not set

H.U.V. de la Victoria, Málaga, Not set

Hospital Universitario de Salamanco, Salamanca, Not set

Hospital Universitario Doctor Peset, Valencia, Not set

H. Quirón Zaragoza, Zaragoza, Not set

Chang Gung Medical Foundation, Chiayi City, Chiayi

China Medical University Hospital - Hematology/Onc, Taichung City, Not set

Tri-Service General Hospital, Taipei, Not set

Medical Park Mersin Hastanesi, Mersin, Içel

Sakarya Research and Training Hospital - Medical Oncology, Adapazarı, Not set

Gazi University Medical Faculty, Ankara, Not set

Ankara University Medical Facu, Ankara, Not set

Istanbul üniversitesi cerrahpaşa, Istanbul, Not set

Medipol Bagcilar Mega Hospital, Istanbul, Not set

Marmara university pendik training and research hospital, Istanbul, Not set

Ege Universitesi Tip Fakultesi, Izmir, Not set

Mersin University Medical Faculty, Yenisehir/Mersin, Not set

Maidstone Hospital, Maidstone, Kent

St Bartholomew's Hospital, London, Not set

Guys and St Thomas' Hospital, London, Not set

Oxford University Hospitals, Oxford, Not set

Conditions: Myelofibrosis

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EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

NCT06556563

Recruiting

This is a multicenter, two-arm, randomized, double-blind, placebo-controlled study of Optune® (Tumor Treating Fields at 200 kHz) together with maintenance Temozolomide (TMZ) chemotherapy agent and pembrolizumab compared to Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the study is to evaluate the Overall Survival (OS).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: University of Southern California, Los Angeles, California +35 locations

University of Southern California, Los Angeles, California

Hoag Memorial Hospital Presbyterian, Newport Beach, California

Stanford Cancer Institute, Palo Alto, California

UF Health Neuromedicine, Gainesville, Florida

Miami Cancer Institute, Miami, Florida

Moffitt Cancer Center, Tampa, Florida

University of Kentucky Medical Center, Lexington, Kentucky

Tufts Medical Center, Boston, Massachusetts

Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota

Washington University, Saint Louis, Missouri

John Theurer Cancer Center/ Hackensack Meridian Health, Hackensack, New Jersey

Montefiore Medical Center- Montefiore Medical Park, Bronx, New York

Northwell Health, Lake Success, New York

Columbia University Irving Medical Center, New York, New York

Duke University Medical Center, Durham, North Carolina

University Hospitals Cleveland Medical Center, Cleveland, Ohio

The Cleveland Clinic, Cleveland, Ohio

Thomas Jefferson University, Sidney Kimmel Comprehensive Cancer Center, Clinical Trials Organization, Philadelphia, Pennsylvania

UPMC Hillman Cancer Center, Pittsburg, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

University of Texas, MD Anderson Cancer Center, Houston, Texas

Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah

Inova Schar Cancer Institute, Fairfax, Virginia

Swedish Medical Center, Seattle, Washington

Centre Hospitalier Universitaire de Lyon, Bron, Not set

Hopital de la Timone, Marseille, Not set

Hopital Saint-Louis, Paris, Not set

Groupe Hospitalier Pitie - Salpetriere, Paris, Not set

Institut Claudius Regaud, Toulouse, Not set

Rabin Medical Center- Beilinson Hospital, Petah tikva, Not set

Chaim Sheba Medical Center, Ramat Gan, Not set

Tel-Aviv Sourasky Medical Center, Tel Aviv, Not set

Queen Elizabeth Hospital, Birmingham, Not set

Addenbrooke's Hospital (Cambridge University Hospitals NHS Foundation Trust), Cambridge, Not set

The Christie Hospital, Manchester, Not set

Royal Marsden, Sutton, Not set

Conditions: Glioblastoma

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IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma

NCT05987332

Recruiting

This is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotinib or investigator's choice of treatment (pembrolizumab, ipilimumab + nivolumab, or dacarbazine).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Honor Health, Scottsdale, Arizona +66 locations

Honor Health, Scottsdale, Arizona

Moores Cancer Center, La Jolla, California

UCLA Medical Center, Los Angeles, California

The Angeles Clinic and Research Institute, Los Angeles, California

California Pacific Medical Center (CPMC), San Francisco, California

University of California San Francisco, San Francisco, California

University of Colorado Cancer Center, Aurora, Colorado

SCRI at HealthONE, Denver, Colorado

University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida

Moffitt Cancer Center, Tampa, Florida

Northside Hospital Atlanta, Atlanta, Georgia

University of Iowa, Iowa City, Iowa

Massachusetts General Hospital, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

The Cancer and Hematology Centers, Grand Rapids, Michigan

Minnesota Oncology Hematology, P.A., Burnsville, Minnesota

Mayo Clinic, Rochester, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Roswell Park Cancer Institute, Buffalo, New York

Northwell Health, Manhasset, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Duke University Health System, Durham, North Carolina

University of Cincinnati, Cincinnati, Ohio

The Cleveland Clinic Foundation, Cleveland, Ohio

Thomas Jefferson University, Philadelphia, Pennsylvania

University of Pittsburgh Medical Center, Pittsburg, Pennsylvania

SCRI Oncology Partners, Nashville, Tennessee

Texas Oncology- DFW, Dallas, Texas

UT Southwestern Medical Center, Dallas, Texas

Houston Methodist Cancer Center, Houston, Texas

MD Anderson Cancer Center, Houston, Texas

Westmead Hospital, Sydney, New South Wales

Princess Alexander Hospital, Brisbane, Queensland

Peter MacCallum Cancer Centre, Melbourne, Victoria

Alfred Health, Melbourne, Victoria

Sir Charles Gairdner Hospital, Perth, Washington

Queen Elizabeth Hospital, Adelaide, Not set

Cliniques Universitaires Saint Luc, Brussels, Not set

Cross Cancer Institute, University of Alberta, Edmonton, Alberta

BC Cancer Agency, Vancouver, British Columbia

Princess Margaret Cancer Centre, Toronto, Ontario

Centre Hospitalier de l'Universite de Montreal- CHUM, Montréal, Quebec

The Leon Berard Center, Lyon, Not set

Institut Curie, Paris, Not set

NCT Heidelberg, Heidelberg, Baden- Württemberg

Universitätsklinikum Essen (AöR), Essen, North Rhine-Westphalia

Universitätsklinikum Köln, Köln, North Rhine-Westphalia

Universitätsklinikum Carl Gustav Carus Dresden, Dresden, Saxony

Charité - Universitätsmedizin Berlin, Berlin, Not set

Hadassah Medical Center, Jerusalem, Not set

Sheba Medical Center, Ramat-Gan, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Not set

Istituto Nazionale dei Tumori Fondazione Pascale, Napoli, Not set

Fondazione Policlinico Gemelli IRCCS, Roma, Not set

AOUS Policlinico Le Scotte, Siena, Not set

LUMC (Leids Universitair Medisch Centrum), Leiden, Not set

Ośrodek Badań Klinicznych Wczesnych Faz, Uniwersyteckie Centrum Kliniczne w Gdańsku, Gdańsk, Not set

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie Państwowy Instytut Badawczy, Warsaw, Not set

Catalan Institute of Oncology, L'Hospitalet de Llobregat, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

Hospital General Universitario Valencia, Valencia, Not set

Dermatologische Klinik, USZ Flughafen Geschoss 7 - Klinische Forschung, Zuerich, Not set

The Beatson West of Scotland Cancer Centre, Glasgow, Not set

Mount Vernon Cancer Centre East & North Herts NHS Trust, Northwood, Not set

The Clatterbridge Cancer Centre NHS Foundation Trust, Wirral, Not set

Conditions: Metastatic Uveal Melanoma

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