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All Clinical Trials in United Kingdom
A listing of 3097 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)
Recruiting
The purpose of this study is to assess the effectiveness of nipocalimab when compared to placebo in decreasing the risk of fetal anemia (a condition in which a baby's red blood cell volume falls below normal levels while the baby is developing in the womb) with live neonates in pregnant participants at risk for severe hemolytic disease of the fetus and newborn.
The purpose of this study is to assess the effectiveness of nipocalimab when compared to placebo in decreasing the risk of fetal anemia (a condition in which a baby's red blood cell volume falls below normal levels while the baby is developing in the womb) with live neonates in pregnant participants at risk for severe hemolytic disease of the fetus and newborn. Read Less
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
08/14/2025
Locations: Kaiser Permanente Los Angeles Medical Center, Los Angeles, California +55 locations
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California
UC Davis School of Medicine, Sacramento, California
Childrens Hospital Colorado, Aurora, Colorado
Advocate Children's Hospital, Park Ridge, Illinois
Riley Children s Hospital, Indianapolis, Indiana
University of Kentucky Medical Center, Lexington, Kentucky
Johns Hopkins Hospital, Baltimore, Maryland
Midwest Fetal Care Center, Minneapolis, Minnesota
Columbia University Medical Center, New York, New York
University of North Carolina (UNC) - School of Medicine, Chapel Hill, North Carolina
University of Cincinnati, Cincinnati, Ohio
Oregon Health and Science University, Portland, Oregon
Lehigh Valley Hospital, Allentown, Pennsylvania
University of Texas Dell Medical School Department of Women's Health, Austin, Texas
University Of Texas Medical Branch At Galveston, Galveston, Texas
Eastern Virginia Medical School, Norfolk, Virginia
Hospital Italiano de Buenos Aires, Buenos Aires, Not set
Hospital Privado Universitario De Cordoba, Cordoba, Not set
Mater Hospital Brisbane, South Brisbane, Not set
Liverpool Hospital, Sydney, Not set
Medizinische Universitaet Wien, Vienna, Not set
C.H.U. Brugmann, Bruxelles, Not set
Universitair Ziekenhuis Leuven, Leuven, Not set
Universidade Federal De Minas Gerais, Belo Horizonte, Not set
Empresa Brasileira de Servicos Hospitalares EBSERH Hospital das Clinicas da UFG, Goiania, Not set
Instituto de Medicina Integral Professor Fernando Figueira, Recife, Not set
Instituto D Or de Pesquisa e Ensino IDOR, Rio de Janeiro, Not set
Hospital Das Clinicas Da Faculdade De Medicina Da USP, Sao Paulo, Not set
BC Women's Hospital University of British Columbia, Vancouver, British Columbia
Centre Hospitalier Sainte Justine, Montreal, Quebec
McGill University Health Centre, Montreal, Quebec
Hospices Civils de Lyon - Groupement Hospitalier Est - Hopital Femme Mere Enfant, Bron, Not set
CHRU Lille, Lille Cedex, Not set
Hopital Armand Trousseau, Paris, Not set
Charite Universitaetsmedizin Berlin, Berlin, Not set
Universitaetsklinikum Giessen und Marburg Standort Giessen, Giessen, Not set
Rotunda Hospital, Dublin, Not set
Hadassah mount scopus, Jerusalem, Not set
Rabin Medical Center, Petah Tikva, Not set
The Chaim Sheba Medical Center, Ramat Gan, Not set
Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Not set
Kyushu University Hospital, Fukuoka, Not set
Gifu Prefectural General Medical Center, Gifu, Not set
Osaka Women's and Children's Hospital, Izumi-shi, Not set
Toho University Medical Center Omori Hospital, Ota, Not set
Miyagi Children's Hospital, Sendai, Not set
Leiden University Medical Center, Leiden, Not set
Hosp Univ Vall D Hebron, Barcelona, Not set
Hosp. Univ. La Paz, Madrid, Not set
Hosp. Virgen Del Rocio, Sevilla, Not set
Karolinska Universitetssjukhuset Huddinge, Stockholm, Not set
Birmingham Women's Hospital, Birmingham, Not set
Leeds Teaching Hospitals NHS Trust, Leeds, Not set
St Georges Hospital, London, Not set
St.Mary's Hospital, Manchester, Not set
John Radcliffe Hospital, Oxford, Not set
Conditions: Hemolytic Disease of the Fetus and Newborn
A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis
Recruiting
The purpose of this study is to measure the pharmacokinetics (PK), pharmacodynamics (PD), safety, tolerability, and immunogenicity of efgartigimod PH20 SC in pediatric participants with gMG aged 2 to \<18 years. The primary goal is to confirm an appropriate dose of efgartigimod PH20 SC for pediatric patients using PK and PD results from this study. Participants will receive injections of efgartigimod PH20 SC and will be monitored for safety until the end of the study. At the end of the follow-up... Read More
The purpose of this study is to measure the pharmacokinetics (PK), pharmacodynamics (PD), safety, tolerability, and immunogenicity of efgartigimod PH20 SC in pediatric participants with gMG aged 2 to \<18 years. The primary goal is to confirm an appropriate dose of efgartigimod PH20 SC for pediatric patients using PK and PD results from this study. Participants will receive injections of efgartigimod PH20 SC and will be monitored for safety until the end of the study. At the end of the follow-up period, eligible participants may roll over to an open-label extension (OLE) study.
The participants will be in the study for up to 14 weeks. Read Less
Gender:
ALL
Ages:
Between 2 years and 17 years
Trial Updated:
08/14/2025
Locations: Carolinas HealthCare System Neurosciences Institute - Neurology, Charlotte, North Carolina +16 locations
Carolinas HealthCare System Neurosciences Institute - Neurology, Charlotte, North Carolina
Neurology Rare Disease Center, Denton, Texas
University of Virginia, Charlottesville, Virginia
UZ Gent, Gent, Not set
Fakultni nemocnice Brno, Brno, Not set
Fakultni nemocnice Ostrava, Ostrava, Not set
AP-HM- Hôpital de La Timone, Marseille, Not set
Universitätsklinikum Essen, Essen, Not set
Hadassah Medical Center- Ein Kerem, Jerusalem, Not set
Schneider Children's Medical Center of Israel, Petah Tikvah, Not set
Tel Aviv Sourasky Medical Center Ichilov, Tel Aviv, Not set
Istituto G Gaslini Ospedale Pediatrico IRCCS, Genova, Not set
Leiden University Medical Center, Leiden, Not set
Neurologia Śląska Centrum Medyczne, Katowice, Not set
Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Not set
Hôpital Nestlé, Lausanne, Not set
Oxford Children's Hospital, Oxford, Not set
Conditions: Generalized Myasthenia Gravis
A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 75 Years With gMG.
Recruiting
The study is a randomized, double-blind, placebo-controlled, multicenter, Phase III study, to evaluate efficacy, safety and tolerability of iptacopan in patients with AChR+ gMG who are on stable SOC treatment. Participants who meet the eligibility criteria will be randomized in a ratio of 1:1, to receive either iptacopan or matching placebo, for 6 months (180 days) while continuing on a stable SOC treatment. The randomization will be stratified based on region.
The study is a randomized, double-blind, placebo-controlled, multicenter, Phase III study, to evaluate efficacy, safety and tolerability of iptacopan in patients with AChR+ gMG who are on stable SOC treatment. Participants who meet the eligibility criteria will be randomized in a ratio of 1:1, to receive either iptacopan or matching placebo, for 6 months (180 days) while continuing on a stable SOC treatment. The randomization will be stratified based on region. Read Less
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/14/2025
Locations: Honor Health Research Institute, Scottsdale, Arizona +72 locations
Honor Health Research Institute, Scottsdale, Arizona
Fullerton Neuro and Headache Ctr, Fullerton, California
SC3 Research Pasadena, Pasadena, California
Neurology Offices Of South Florida, Boca Raton, Florida
Superior Associates in Research LLC, Hialeah, Florida
Augusta University Georgia, Augusta, Georgia
Hawaii Pacific Neuroscience LLC, Honolulu, Hawaii
University of Chicago Medical Centr, Chicago, Illinois
Prairie Heart Institute, Springfield, Illinois
Duke University Medical Center, Durham, North Carolina
Neuroscience Research Ctr, Canton, Ohio
Ohio State University Medical Center, Columbus, Ohio
Penn Presbyterian Medical Center, Philadelphia, Pennsylvania
Vanderbilt University Medical CenterX, Nashville, Tennessee
Nerve and Muscle Center of Texas, Houston, Texas
Central TX Neuro Consultants P A, Round Rock, Texas
Novartis Investigative Site, Guangzhou, Guangdong
Novartis Investigative Site, Shenzhen, Guangdong
Novartis Investigative Site, Shijiazhuang, Hebei
Novartis Investigative Site, Changsha, Hunan
Novartis Investigative Site, Suzhou, Jiangsu
Novartis Investigative Site, Nanchang, Jiangxi
Novartis Investigative Site, Xianyang, Shaanxi
Novartis Investigative Site, Xian, Shaanxi
Novartis Investigative Site, Beijing, Not set
Novartis Investigative Site, Fujian, Not set
Novartis Investigative Site, Jinan, Not set
Novartis Investigative Site, Chaidari, Attiki
Novartis Investigative Site, Larissa, GR
Novartis Investigative Site, Athens, Not set
Novartis Investigative Site, Patras, Not set
Novartis Investigative Site, Thessaloniki, Not set
Novartis Investigative Site, Haifa, Not set
Novartis Investigative Site, Jerusalem, Not set
Novartis Investigative Site, Bologna, BO
Novartis Investigative Site, Firenze, FI
Novartis Investigative Site, Genova, GE
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Palermo, PA
Novartis Investigative Site, Palermo, PA
Novartis Investigative Site, Roma, RM
Novartis Investigative Site, Roma, RM
Novartis Investigative Site, Roma, RM
Novartis Investigative Site, Napoli, Not set
Novartis Investigative Site, Narita, Chiba
Novartis Investigative Site, Fukuoka city, Fukuoka
Novartis Investigative Site, Fukushima city, Fukushima
Novartis Investigative Site, Sapporo city, Hokkaido
Novartis Investigative Site, Nishinomiya, Hyogo
Novartis Investigative Site, Hanamaki, Iwate
Novartis Investigative Site, Sendai-shi, Miyagi
Novartis Investigative Site, Suita, Osaka
Novartis Investigative Site, Higashimatsuyama, Saitama
Novartis Investigative Site, Shinjuku Ku, Tokyo
Novartis Investigative Site, Chiba, Not set
Novartis Investigative Site, Hiroshima, Not set
Novartis Investigative Site, Lublin, Lubelskie
Novartis Investigative Site, Katowice, Slaskie
Novartis Investigative Site, Krakow, Not set
Novartis Investigative Site, Rzeszow, Not set
Novartis Investigative Site, Lisboa, Not set
Novartis Investigative Site, Lisboa, Not set
Novartis Investigative Site, Porto, Not set
Novartis Investigative Site, Vila Nova De Gaia, Not set
Novartis Investigative Site, Pozuelo de Alarcon, Madrid
Novartis Investigative Site, Alicante, Not set
Novartis Investigative Site, Barcelona, Not set
Novartis Investigative Site, Inverness, Invernesshire
Novartis Investigative Site, Ilford, London
Novartis Investigative Site, Swinton, Manchester
Novartis Investigative Site, Birmingham, Not set
Novartis Investigative Site, Liverpool, Not set
Novartis Investigative Site, Southampton, Not set
Conditions: Generalized Myasthenia Gravis
Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]
Recruiting
This is a phase 3 study of pembrolizumab in combination with carboplatin/taxane (paclitaxel or nab-paclitaxel) followed by pembrolizumab with or without maintenance sacituzumab tirumotecan (sac-TMT; MK-2870) in first-line treatment of metastatic squamous non-small cell lung cancer. It is hypothesized that pembrolizumab with maintenance sacituzumab tirumotecan is superior to pembrolizumab without sacituzumab tirumotecan maintenance with respect to overall survival (OS).
This is a phase 3 study of pembrolizumab in combination with carboplatin/taxane (paclitaxel or nab-paclitaxel) followed by pembrolizumab with or without maintenance sacituzumab tirumotecan (sac-TMT; MK-2870) in first-line treatment of metastatic squamous non-small cell lung cancer. It is hypothesized that pembrolizumab with maintenance sacituzumab tirumotecan is superior to pembrolizumab without sacituzumab tirumotecan maintenance with respect to overall survival (OS). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: CARTI Cancer Center ( Site 0006), Little Rock, Arkansas +188 locations
CARTI Cancer Center ( Site 0006), Little Rock, Arkansas
Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center ( Site 0122), Burbank, California
Exempla Lutheran Medical Center ( Site 0119), Golden, Colorado
Intermountain Health St. Mary's Regional Hospital ( Site 0116), Grand Junction, Colorado
Mid Florida Hematology and Oncology Center ( Site 0109), Orange City, Florida
Centricity Research Columbus Cancer Center ( Site 0111), Columbus, Georgia
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital ( Site 0001), Marietta, Georgia
University of Chicago Medical Center ( Site 0145), Chicago, Illinois
Allina Health Cancer Institute - Abbott Northwestern Hospital ( Site 0146), Minneapolis, Minnesota
New Mexico Oncology Hematology Consultants Ltd. ( Site 0123), Albuquerque, New Mexico
Thomas Jefferson University - Clinical Research Institute ( Site 0147), Philadelphia, Pennsylvania
Oncology Consultants P.A. ( Site 0124), Houston, Texas
Mays Cancer Center ( Site 0132), San Antonio, Texas
Instituto Alexander Fleming ( Site 0203), Ciudad Autónoma de Buenos Aires, Buenos Aires
Instituto de Investigaciones Clínicas Mar del Plata ( Site 0200), Mar del Plata, Buenos Aires
Instituto Médico Río Cuarto ( Site 0204), Rio Cuarto., Cordoba
Fundacion Intecnus ( Site 0205), San Carlos de Bariloche, Rio Negro
Sanatorio Parque ( Site 0201), Rosario, Santa Fe
Hospital Aleman-Oncology ( Site 0202), Buenos Aires, Not set
Ordensklinikum Linz GmbH Elisabethinen-Department of Pneumology ( Site 0720), Linz, Oberosterreich
Klinik Hietzing ( Site 0740), Wien, Not set
Standort Penzing der Klinik Ottakring-Abteilung für Atemwegs-und Lungenkrankheiten ( Site 0730), Wien, Not set
Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 0710), Wien, Not set
Hospital do Cancer de Pernambuco ( Site 0312), Recife, Pernambuco
Oncoclínica Oncologistas Associados ( Site 0309), Terezina, Piaui
Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 0311), Porto Alegre, Rio Grande Do Sul
Hospital Nossa Senhora da Conceição ( Site 0300), Porto Alegre, Rio Grande Do Sul
Instituto de Oncologia Saint Gallen ( Site 0304), Santa Cruz do Sul, Rio Grande Do Sul
Hospital de Base de São José do Rio Preto ( Site 0310), São José do Rio Preto, Sao Paulo
Hospital Paulistano ( Site 0307), Sao Paulo, Not set
Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 0100), Kingston, Ontario
Waterloo Regional Health Network (WRHN) ( Site 0153), Kitchener, Ontario
St. Marys Hospital Center ( Site 0105), Montreal, Quebec
McGill University Health Centre ( Site 0103), Montréal, Quebec
Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-centre-du-quebec ( Site 0106), Trois-Rivières, Quebec
Centro de Investigación del Maule ( Site 0419), Talca, Maule
FALP ( Site 0409), Santiago, Region M. De Santiago
Pontificia Universidad Catolica de Chile-Hemato-Oncology ( Site 0402), Santiago, Region M. De Santiago
Bradfordhill-Clinical Area ( Site 0407), Santiago, Region M. De Santiago
ONCOCENTRO APYS-ACEREY ( Site 0400), Viña del Mar, Valparaiso
Bradford Hill Norte ( Site 0420), Antofagasta, Not set
Beijing Cancer Hospital ( Site 2411), Beijing, Beijing
Beijing Cancer hospital-intrathoratic deparmtment II ( Site 2410), Beijing, Beijing
Peking Union Medical College Hospital ( Site 2412), Beijing, Beijing
Army Medical Center of People's Liberation Army-respiratory ( Site 2426), Chongqing, Chongqing
Fujian Provincial Cancer Hospital ( Site 2419), Fuzhou, Fujian
The First Affiliated hospital of Xiamen University-oncology ( Site 2420), Xiamen, Fujian
The First Affiliated Hospital of Guangzhou Medical University ( Site 2417), Guangzhou, Guangdong
Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( Site 2416), Guangzhou, Guangdong
Harbin Medical University Cancer Hospital-oncology of department ( Site 2415), Harbin, Heilongjiang
Henan Cancer Hospital-Pneumology department ( Site 2423), Zhengzhou, Henan
Tongji Hospital Tongji Medical,Science & Technology ( Site 2424), Wuhan, Hubei
The Second Xiangya Hospital of Central South University-Oncology ( Site 2418), Changsha, Hunan
First Huai'an Hospital Affiliated to Nanjing Medical University ( Site 2402), Huai'an, Jiangsu
Northern Jiangsu People's Hospital-General Surgery Department ( Site 2403), Yangzhou, Jiangsu
The Second Affiliated Hospital of Nanchang University-Oncology Department ( Site 2405), Nanchang, Jiangxi
The First affiliated hospital of Nanchang University (Xianghu campus) ( Site 2404), Nanchang, Jiangxi
Jilin Province Tumor Hospital-GCP office ( Site 2413), Changchun, Jilin
The First Hospital of Jilin University-Oncology ( Site 2414), Changchun, Jilin
Shanghai East Hospital ( Site 2428), Shanghai, Shanghai
Shanghai Pulmonary Hospital ( Site 2427), Shanghai, Shanghai
West China Hospital, Sichuan University ( Site 2422), Cheng Du, Sichuan
Sichuan Cancer hospital. ( Site 2421), Chengdu, Sichuan
The Affiliated Cancer Hospital of Xinjiang Medical University ( Site 2425), Urumqi, Xinjiang
The first Affiliated Hospital, Zhejiang University School of Medicine-Respiratory Department ( Site 2406), Hangzhou, Zhejiang
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine-Medical Oncology ( Site 2407), Hangzhou, Zhejiang
Zhejiang Cancer Hospital-Breast Oncology ( Site 2408), Hangzhou, Zhejiang
Taizhou Hospital of Zhejiang Province ( Site 2430), Taizhou, Zhejiang
The First Affiliated Hospital of Wenzhou Medical University-Respiratory department ( Site 2409), Wenzhou, Zhejiang
Centro Cancerológico del Caribe (CECAC) ( Site 0509), Barranquilla, Atlantico
Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0501), Valledupar, Cesar
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0500), Bogota, Distrito Capital De Bogota
Oncologos del Occidente ( Site 0504), Pereira., Risaralda
Fundación Valle del Lili-Oncology CIC ( Site 0505), Cali, Valle Del Cauca
Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0800), Brno, Brno-mesto
Nemocnice AGEL Ostrava - Vitkovice a.s.-Plicni oddeleni ( Site 0803), Ostrava-Vitkovice, Ostrava Mesto
Fakultni nemocnice Olomouc-Klinika plicnich nemoci a tuberkulozy ( Site 0802), Olomouc, Not set
Clinique Clairval ( Site 0904), Marseille, Bouches-du-Rhone
Hôpital Robert Schuman ( Site 0907), Vantoux, Lorraine
Institut de Cancérologie de l'Ouest ( Site 0908), ANGERS cedex 02, Maine-et-Loire
Sainte Catherine Institut du Cancer Avignon Provence ( Site 0902), Avignon, Vaucluse
CHD Vendee ( Site 0901), La Roche-sur-Yon, Vendee
Hôpital Saint-Louis ( Site 0906), Paris, Not set
GEFOS Gesellschaft f. onkologische Studien ( Site 1005), Dortmund, Nordrhein-Westfalen
Universitätsklinikum Schleswig-Holstein-Pneumologie ( Site 1000), Luebeck, Schleswig-Holstein
SRH Wald-Klinikum Gera-Zentrum für klinische Studien ( Site 1006), Gera, Thuringen
Charité Campus Virchow-Klinikum-Department of Infectious Diseases and Pulmonary Medicine ( Site 1003), Berlin, Not set
Bacs-Kiskun Varmegyei Oktatokorhaz ( Site 1100), Kecskemét, Bacs-Kiskun
Petz Aladar Egyetemi Oktato Korhaz ( Site 1101), Gyor, Gyor-Moson-Sopron
Jász-Nagykun-Szolnok Vármegyei Hetényi Géza Kórház-Onkologiai Kozpont ( Site 1103), Szolnok, Jasz-Nagykun-Szolnok
Reformatus Pulmonologiai Centrum ( Site 1102), Torokbalint, Pest
Zala Megyei Szent Rafael Kórház ( Site 1110), Zalaegerszeg, Zala
Országos Korányi Pulmonológiai Intézet ( Site 1104), Budapest, Not set
St. James's Hospital ( Site 1200), Dublin, Not set
Rambam Health Care Campus-Oncology Division ( Site 1302), Haifa, Not set
Shaare Zedek Medical Center ( Site 1300), Jerusalem, Not set
Rabin Medical Center ( Site 1303), Petah Tikva, Not set
Sheba Medical Center ( Site 1301), Ramat Gan, Not set
Istituto Nazionale Tumori IRCCS Fondazione Pascale-Oncologia clinica sperimentale Toraco-Polmonare ( Site 1401), Napoli, Campania
Azienda Ospedaliera S. Giovanni Addolorata-Oncologia Medica ( Site 1409), Roma, Lazio
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1404), Milan, Lombardia
Fondazione IRCCS San Gerardo dei Tintori-Oncologia ( Site 1412), Monza, Lombardia
Istituto Clinico Humanitas-U.O di Oncologia medica ed Ematologia ( Site 1408), Rozzano, Milano
Istituto Nazionale Tumori Regina Elena-Oncologia Medica 2 ( Site 1402), Rome, Roma
Azienda Ospedaliera Spedali Civili di Brescia-Oncology ( Site 1414), Brescia, Not set
Ospedale San Martino ( Site 1407), Genova, Not set
Fondazione IRCCS Policlinico San Matteo-Oncology ( Site 1410), Pavia, Not set
Ospedale di Circolo e Fondazione Macchi Varese-Oncology ( Site 1413), Varese, Not set
Aichi Cancer Center ( Site 2502), Nagoya, Aichi
Nagoya University Hospital ( Site 2519), Nagoya, Aichi
Fujita Health University Hospital ( Site 2515), Toyoake, Aichi
Hirosaki University Hospital ( Site 2514), Hirosaki, Aomori
Ehime University Hospital ( Site 2511), Toon, Ehime
Gunma Prefectural Cancer Center ( Site 2510), Ota, Gunma
Takarazuka City Hospital ( Site 2508), Takarazuka, Hyogo
Kanazawa University Hospital ( Site 2513), Kanazawa, Ishikawa
St. Marianna University Hospital ( Site 2521), Kawasaki, Kanagawa
Kanagawa Cardiovascular and Respiratory Center ( Site 2518), Yokohama, Kanagawa
Kanagawa Cancer Center ( Site 2504), Yokohama, Kanagawa
Matsusaka Municipal Hospital ( Site 2522), Matsusaka, Mie
Sendai Kousei Hospital ( Site 2507), Sendai, Miyagi
Kansai Medical University Hospital ( Site 2503), Hirakata, Osaka
Saitama Prefectural Cancer Center ( Site 2512), Kitaadachi-gun, Saitama
Cancer Institute Hospital of JFCR ( Site 2500), Koto, Tokyo
Toho University Omori Medical Center ( Site 2520), Ota, Tokyo
National Center for Global Health and Medicine ( Site 2516), Shinjuku, Tokyo
National Hospital Organization Yamaguchi Ube Medical Center ( Site 2523), Ube, Yamaguchi
Chiba University Hospital ( Site 2517), Chiba, Not set
National Hospital Organization Kyushu Medical Center ( Site 2509), Fukuoka, Not set
Niigata Cancer Center Hospital ( Site 2505), Niigata, Not set
Osaka International Cancer Institute ( Site 2506), Osaka, Not set
The Catholic University of Korea, Incheon St. Mary's Hospital ( Site 2106), Bupyeong-gu, Incheon
Pusan National University Yangsan Hospital ( Site 2104), Yangsan-si, Kyongsangnam-do
Pusan National University Hospital ( Site 2100), Busan, Pusan-Kwangyokshi
Kyungpook National University Chilgok Hospital-Pulmonology ( Site 2102), Deagu, Taegu-Kwangyokshi
Chungnam national university hospital-Department of Internal Medicine ( Site 2107), Daejeon, Taejon-Kwangyokshi
Kyung Hee University Hospital ( Site 2101), Seoul, Not set
Asan Medical Center ( Site 2105), Seoul, Not set
Korea University Guro Hospital-Internal Medicine ( Site 2103), Seoul, Not set
Clínicas AUNA Sede Chiclayo ( Site 0604), Chiclayo, Lambayeque
Oncosalud-Clinical Research ( Site 0600), Lima, Not set
Hospital Militar Central Coronel Luis Arias Schereiber ( Site 0602), Lima, Not set
Wielkopolskie Centrum Pulmonologii i Torakochirurgii-Oddzial Onkologii Klinicznej z Pododdzialem Dz ( Site 1510), Poznań, Dolnoslaskie
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1503), Bydgoszcz, Kujawsko-pomorskie
Regionalny Szpital Specjalistyczny im. dr. Władyslawa Biegańskiego ( Site 1513), Grudziadz, Kujawsko-pomorskie
Szpital Specjalistyczny im. Henryka Klimontowicza ( Site 1507), Gorlice, Malopolskie
Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie-Oncology Department ( Site 1515), Kraków, Malopolskie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 1500), Warszawa, Mazowieckie
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1501), Przemysl, Podkarpackie
Szpital Wojewódzki w Koszalinie. ( Site 1517), Poland, Zachodniopomorskie
Centrul Medical Medicover Victoria ( Site 2000), Bucharest, Bucuresti
Cardiomed SRL Cluj-Napoca ( Site 2002), Cluj-Napoca, Cluj
SC Radiotherapy Center Cluj SRL-Oncologie Medicala ( Site 2001), Florești, Cluj
Centrul de Oncologie Sfantul Nectarie-Medical ( Site 2004), Craiova, Dolj
Cabinet Medical Oncomed ( Site 2005), Timisoara, Timis
SC ONCO CARD SRL ( Site 2007), Brasov, Not set
Clinica Polisano ( Site 2008), Sibiu, Not set
CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 1703), Santiago de Compostela, Galicia
Hospital Insular de Gran Canaria-Oncology ( Site 1701), Las Palmas de Gran Canaria, Las Palmas
Hospital Quirón Málaga ( Site 1704), Málaga, Malaga
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1700), Barcelona, Not set
Hospital Universitario Fundación Jiménez Díaz-Oncology & Hematology ( Site 1702), Madrid, Not set
Hospital Universitario Virgen de Valme-Departamento de Oncologia ( Site 1705), Sevilla, Not set
National Taiwan University Cancer Center (NTUCC) ( Site 2209), Taipei City, Taipei
Taoyuan General Hospital ( Site 2203), Taoyuan City, Taoyuan
Chang Gung Memorial Hospital at Kaohsiung ( Site 2207), Kaohsiung, Not set
Taichung Veterans General Hospital ( Site 2204), Taichung, Not set
National Cheng Kung University Hospital ( Site 2205), Tainan, Not set
National Taiwan University Hospital-Oncology ( Site 2208), Taipei, Not set
Mackay Memorial Hospital-Chest Medicine ( Site 2201), Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch-Clinic of Chest Medicine ( Site 2202), Taoyuan, Not set
Prapokklao Hospital ( Site 2306), Mueang, Chanthaburi
Faculty of Medicine - Khon Kaen University ( Site 2305), Muang, Khon Kaen
Faculty of Medicine Siriraj Hospital ( Site 2301), Bangkok, Krung Thep Maha Nakhon
Bangkok Metropolitan Administration Medical College and Vajira Hospital ( Site 2300), Dusit, Krung Thep Maha Nakhon
Lampang Cancer Hospital ( Site 2304), Mueang Lampang, Lampang
Songklanagarind hospital ( Site 2303), HatYai, Songkhla
Maharaj Nakorn Chiang Mai Hospital ( Site 2302), Chiang Mai, Not set
Medipol Mega Universite Hastanesi-oncology ( Site 1811), Stanbul, Istanbul
Hacettepe Universite Hastaneleri-oncology hospital ( Site 1801), Ankara, Not set
Gazi Universitesi-Oncology ( Site 1804), Ankara, Not set
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1800), Ankara, Not set
Memorial Kayseri Hastanesi ( Site 1805), Kayseri, Not set
Mersin Sehir Eğitim ve Araştırma Hastanesi-Oncology ( Site 1808), Mersin, Not set
Samsun Medical Park Hastanesi-medical oncology ( Site 1806), Samsun, Not set
Burjeel Medical City ( Site 2600), Abu Dhabi, Abu Zaby
Torbay Hospital ( Site 1906), Torquay, Devon
St Bartholomew's Hospital ( Site 1901), London, London, City Of
City Hospital, Nottingham University Hospitals NHS Trust-NCCTT ( Site 1911), Nottingham, Nottinghamshire
Conditions: Non-small Cell Lung Cancer, NSCLC
ESPERANZA: External Control Arm Study for T-DXd for Patients With HER2 IHC3+ Solid Tumors
Recruiting
In DESTINY-Pan-Tumor \[DP-02\], DESTINY CRC02 \[DC-02\], and DESTINY-Lung01 \[DL-01\], T-DXd demonstrated tumor response across a broad range of HER2-expressing solid tumors, particularly IHC3+ patients.
This study will use real-world data (RWD) to identify IHC3+ patients in the real world who received standard of care (SoC) and compare them with IHC3+ patients who received T-DXd in the referent trials. The tumors included are: non-small cell lung cancer \[NSCLC\], colorectal cancer \[CRC\], en... Read More
In DESTINY-Pan-Tumor \[DP-02\], DESTINY CRC02 \[DC-02\], and DESTINY-Lung01 \[DL-01\], T-DXd demonstrated tumor response across a broad range of HER2-expressing solid tumors, particularly IHC3+ patients.
This study will use real-world data (RWD) to identify IHC3+ patients in the real world who received standard of care (SoC) and compare them with IHC3+ patients who received T-DXd in the referent trials. The tumors included are: non-small cell lung cancer \[NSCLC\], colorectal cancer \[CRC\], endometrial cancer, bladder cancer, epithelial ovarian cancer, cervical cancer, pancreatic cancer, biliary tract cancers, and other tumors.
This is a real-world external control arm (ECA) study to generate evidence on the comparative effectiveness of T-DXd versus real-world (RW) SoC in adult patients with HER2 IHC3+ solid tumors who have received prior systemic treatment. HER2 IHC3+ patients who initiated 5.4mg/kg of T-DXd in the referent trials (DP-02, DC-02, and DL-01) will be compared against IHC3+ patients who received RW SoC. This will be a retrospective observational study which will use secondary real-world data and data collected in the 3 aforementioned trials.
Objectives: The primary objective of this study is to evaluate the comparative effectiveness with respect to overall survival (OS) for T-DXd vs SoC for patients with HER2 IHC3+ expressing solid tumors in two pooled cohorts: one cohort reflecting the tumors in the three referent trials (referred to as the 'tumor agnostic' cohort), consisting of patients with NSCLC, CRC, endometrial, epithelial ovarian, cervical, pancreatic, biliary tract cancers, and other tumors; and a second cohort reflecting the tumors in the DP-02 trial (referred to as 'pan tumor'), consisting of the same tumors but excluding NSCLC and CRC. Read Less
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
08/14/2025
Locations: Research Site, Spartanburg, South Carolina +26 locations
Research Site, Spartanburg, South Carolina
Research Site, Vienna, Not set
Research Site, Liege, Not set
Research Site, London, Ontario, Not set
Research Site, Olomouc, Not set
Research Site, Copenhagen, Not set
Research Site, Caen, Not set
Research Site, Lille, Not set
Research Site, Marseille, Not set
Research Site, Nice, Not set
Research Site, Paris, Not set
Research Site, Saint-Herblain, Not set
Research Site, Berlin, Not set
Research Site, Frankfurt, Not set
Research Site, Heidelberg, Not set
Research Site, W rzburg, Not set
Research Site, Meldola, Not set
Research Site, Rome, Not set
Research Site, Porto, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Pamplona, Not set
Research Site, Valencia, Not set
Research Site, Leeds, Not set
Research Site, London, Not set
Conditions: Bladder Cancer, Biliary Tract Cancer, Cervical Cancer, Endometrial Cancer, Ovarian Cancer, Pancreatic Cancer, Colorectal Cancer, Lung Cancer, Other Tumors
Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2
Recruiting
This study will enroll participants with urothelial cancer (UC). UC can include cancer of the bladder, kidney, or the tubes that carry pee through the body (ureter, urethra). This study will try to find out if the drugs disitamab vedotin with pembrolizumab works better than platinum-containing chemotherapy to treat patients with UC. This study will also test what side effects happen when participants take these drugs together. A side effect is anything a drug does to the body besides treating th... Read More
This study will enroll participants with urothelial cancer (UC). UC can include cancer of the bladder, kidney, or the tubes that carry pee through the body (ureter, urethra). This study will try to find out if the drugs disitamab vedotin with pembrolizumab works better than platinum-containing chemotherapy to treat patients with UC. This study will also test what side effects happen when participants take these drugs together. A side effect is anything a drug does to the body besides treating the disease.
Participants in this study will have cancer that has spread through the body (metastatic) or spread near where it started (locally advanced).
In this study, there are 2 different groups. Participants will be assigned to a group randomly. Participants in the disitamab vedotin arm will get the study drug disitamab vedotin once every two weeks and pembrolizumab once every 6 weeks. Participants in the standard of care arm will get gemcitabine once a week for 2 weeks with either cisplatin or carboplatin once every 3 weeks. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Banner Gateway Medical Center, Gilbert, Arizona +328 locations
Banner Gateway Medical Center, Gilbert, Arizona
Banner MD Anderson Cancer Center, Gilbert, Arizona
UCLA Hematology/Oncology - Alhambra, Alhambra, California
Foothill Cardioology, Arcadia, California
Beverly Hills Multi-Specialties Practice, Beverly Hills, California
Providence Saint Joseph Medical Center, Burbank, California
UCLA Burbank Cardiology, Burbank, California
UCLA Hematology/Oncology - Burbank, Burbank, California
UCLA Calabasas Specialty Care, Calabasas, California
UCLA Encino Specialty Care (Radiology), Encino, California
UCLA Hematology/Oncology - Encino, Encino, California
Helios Clinical Research, Glendale, California
Foothill Cardiology Glendora, Glendora, California
Helios Clinical Research, Long Beach, California
UCLA Downtown Los Angeles Primary & Specialty Care, Los Angeles, California
Administrative Address: UCLA Hematology/Oncology, Los Angeles, California
UCLA Cardiovascular Center, Los Angeles, California
UCLA Hematology & Oncology Clinic, Los Angeles, California
UCLA Hematology / Oncology, Los Angeles, California
UCLA Westwood Specialty Care, Los Angeles, California
UCLA Montecito Primary & Specialty Care, Montecito, California
Pacific Cancer Care, Monterey, California
Newport Diagnostics, Newport Beach, California
Foothill Cardiology Pasadena, Pasadena, California
Southern California Heart Specialists, Pasadena, California
UCLA Porter Ranch Primary & Specialty Care, Porter Ranch, California
UCSF Center at China Basin Imaging, San Francisco, California
Helen Diller Family Comprehensive Cancer Center - Imaging Divisadero, San Francisco, California
Helen Diller Family Comprehensive Cancer Center - Imaging Post, San Francisco, California
UCSF Cancer Center MZ Phlebotomy, San Francisco, California
UCSF Mount Zion Phlebotomy, San Francisco, California
Helen Diller Family Comprehensive Cancer Center - Imaging Parnassus, San Francisco, California
UCSF Parnassus Phlebotomy, San Francisco, California
UCSF Parnassus-5 Lab, San Francisco, California
Cardiovascular Care and Prevention Center at Mission Bay, San Francisco, California
UCSF Investigational Drugs Pharmacy, San Francisco, California
UCSF Mission Bay Gateway-2 Lab, San Francisco, California
UCSF Mission Bay PCMB-5 Lab, San Francisco, California
UCSF Mission Bay Pediatric Clinical Research Center, San Francisco, California
UCSF Mission Bay Radiology and Nuclear Medicine, San Francisco, California
University of California San Francisco, San Francisco, California
University of California, San Francisco | HDFCCC - Hematopoietic malignancies, San Francisco, California
Diagnostic Medical Group of Southern California, , San Gabriel, CA, San Gabriel, California
Southern California Heart Centers, San Gabriel, California
UCLA Hematology/Oncology - San Luis Obispo, San Luis Obispo, California
Sierra Vista Regional Medical Center, San Luis Obispo, California
Helios Clinical Research, Santa Ana, California
UCLA Hematology/Oncology - Santa Barbara, Santa Barbara, California
UCLA Hematology/Oncology - Santa Monica, Santa Monica, California
UCLA Simi Valley Alamo Specialty Care, Simi Valley, California
Twin Cities Community Hospital, Templeton, California
UCLA Thousand Oaks Primary & Specialty Care, Thousand Oaks, California
UCLA Hematology/Oncology - Torrance, Torrance, California
UCLA Torrance Lomita Specialty Care, Torrance, California
UCLA Santa Clarita Primary & Specialty Care, Valencia, California
UCLA Ventura Cardiology, Ventura, California
UCLA Hematology/Oncology - Westlake, Westlake Village, California
Helios Clinical Research, Whittier, California
Greater Baltimore Medical Center, Baltimore, Maryland
M Health Fairview Ridges Cancer Clinic, Burnsville, Minnesota
M Health Fairview Cancer Clinic-Edina, Edina, Minnesota
Minnesota Oncology Hematology Pa, Edina, Minnesota
Minnesota Oncology Hematology, PA, Fridley, Minnesota
M Health Fairview Maple Grove Cancer Center, Maple Grove, Minnesota
Allina Health Cancer Institute-United(VPCI), Minneapolis, Minnesota
Hennepin Country Medical Center, Minneapolis, Minnesota
M Health Fairview University of Minnesota Investigational Drug Services, Minneapolis, Minnesota
Metro Minnesota Community Oncology Research Consortium(MMCORC), Saint Louis Park, Minnesota
Regions Hospital, Saint Paul, Minnesota
M Health Fairview Lakes Medical Center, Wyoming, Minnesota
Nebraska Medicine- Bellevue Medical Center, Bellevue, Nebraska
Nebraska Medicine -Nebraska Medical Center, Omaha, Nebraska
Nebraska Medicine-Cancer Center at Village Pointe Health Center, Omaha, Nebraska
The University of Nebraska Medical Center, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
Optum Care Cancer Care at Seven Hills, Las Vegas, Nevada
OptumCare Cancer center, Las Vegas, Nevada
OptumCare Cancer Center Care at Fort Apache, Las Vegas, Nevada
Icahn School of Medicine at Mount Sinai, New York, New York
Ship study drug to: Mount Sinai Hospital- Pharmacy Dept, New York, New York
ECU Health Medical Center, Greenville, North Carolina
AHN Saint Vincent Hospital, Erie, Pennsylvania
AHN Jefferson Hospital, Jefferson Hills, Pennsylvania
AHN Forbes Hospital, Monroeville, Pennsylvania
Allegheny Valley Hospital, Natrona Heights, Pennsylvania
AHN Cancer Institute - Allegheny General Hospital, Pittsburgh, Pennsylvania
AHN Cancer Institute Pharmacy, Pittsburgh, Pennsylvania
AHN West Penn Hospital, Pittsburgh, Pennsylvania
UT Southwestern Medical Center - Redbird, Dallas, Texas
University of Texas Southwestern Medical Center - Simmons Cancer Center, Dallas, Texas
University of Texas Southwestern Medical Center-Simmons Cancer Center Pharmacy, Dallas, Texas
University of Texas Southwestern Medical Center, Dallas, Texas
UT Southwestern - Simmons Cancer Center - Fort Worth, Fort Worth, Texas
UT Southwestern - Simmons Cancer Center - Richardson/Plano, Richardson, Texas
Inova Schar Cancer Institue Infusion Pharmacy, Fairfax, Virginia
Inova Schar Cancer Institute, Fairfax, Virginia
Harborview Medical Center, Seattle, Washington
Fred Hutchinson Cancer Center., Seattle, Washington
University of Washington Medical Center, Seattle, Washington
Clinica Viedma, Viedma, RIO Negro
Fundación Dr. Ruben Kowalyszyn, Viedma, RÍO Negro
Comisión Provincial de Evaluación de Proyectos de Investigación en Salud Humana (CEEPISH), Viedma, RÍO Negro
Centro de Oncologia e Investigacion de Buenos Aires (COIBA), Berazategui, Not set
Instituto Médico Especializado Alexander Fleming, Buenos Aires, Not set
Centro Medico Austral, Buenos Aire, Not set
Centro Oncologico Korben, Buenos Aire, Not set
Fundacion Cenit, Caba, Not set
Investigaciones Clinicas Moleculares (ICM), Caba, Not set
CEMAIC - Centro Medico Privado, Cordoba, Not set
Hospital Municipal de Morón. O. B. Lavignolle, Morón, Not set
Centro de Investigacion Pergamino SA, Pergamino, Not set
Comité Provincial de Bioética-Rosario, Rosario, Not set
Sanatorio Parque, Rosario, Not set
Consultorio Dr. Miguel Angel Escudero, Salta, Not set
Oncologia Salta, Salta, Not set
Centro para la Atencion Integral del paciente Oncologico, Tucuman, Not set
Concord Repatriation General Hospital, Concord, New South Wales
Saint Vincents Hospital Sydney - Human Research Ethics Committee, Darlinghurst, New South Wales
St Vincent's Clinic, Darlinghurst, New South Wales
Macquarie University Hospital, Macquarie University, New South Wales
Macquarie University, North Ryde, New South Wales
Prince of Wales Hospital, Randwick, New South Wales
North Shore Private Hospital, St Leonards, New South Wales
Mater Misericordiae - Mater Hospital Brisbane, Brisbane, Queensland
Icon Cancer Centre Chermside, Herston, Queensland
Mater Research, South Bribane, Queensland
Peninsula & South Eastern Hematology and Oncology Group (PASO), Frankston, Victoria
Austin Health, Melbourne, Victoria
South Eastern Sydney Local Health District, Caringbah, Not set
Lyell McEwin Hospital, Elizabeth Vale, Not set
Peninsula And South East Oncology, Frankston, Not set
Cabrini., Malvern, Not set
Mid North Coast Local Health District, NSW, Not set
Port Macquarie Base Hospital, Port Macquarie, Not set
Mater Cancer Care Centre, South Brisbane, Not set
Royal North Shore Hospital, St Leonards, Not set
Algemeen Ziekenhuis Maria Middelares, Gent, Not set
AZ St. Lucas, Ghent, Not set
University Hospital Ghent, Ghent, Not set
CHU de Liege Service Oncologie Medicale, Liege, Not set
CHU UCL Namur-Site de Saint Elisabeth, Namur, Not set
GZA Hospital Sint-Augustinus, Wilrijk, Not set
Centro de Oncologia da Bahia, Salvador, BA
Suporte Nutricional e Quimioterapia - PRONUTRIR, Fortaleza, Ceará
Associacao Mario Penna - Hospital Luxemburgo - NEPI Nucleo de Ensino Pesquisa e Inovacao, Belo Horizonte, MG
Hospital Sao Vicente de Paulo, Passo Fundo, RIO Grande DO SUL
Hospital Mae de Deus, Porto Alegre, RIO Grande DO SUL
Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS
Hospital Nossa Senhora da Conceicao / Grupo Hospitalar Conceicao, Porto Alegre, RS
Fundacao Doutor Amaral Carvalho, Jaú, SÃO Paulo
Hospital de Cancer de Barretos - Fundacao Pio XII, Barretos, Not set
Erasto Gaertner Hospital, CuriBba, Not set
Hospital Alemao Oswaldo Cruz, Sao Paulo, Not set
Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta
University of Alberta / Cross Cancer Institute, Edmonton, Alberta
Lakeridge Health - The R.S. McLaughlin Durham Regional Cancer Centre (MDRCC), Oshawa, Ontario
Princess Margaret Cancer Centre - University Health Network, Toronto, Ontario
Centro de Estudios Clínicos SAGA, Santiago, Not set
Centro de Investigaciones Clinicas Vina del Mar, Vina del mar, Not set
Fakultni nemocnice Hradec Kralove, Hradec Kralove, Hradec Králové
Fakultni Nemocnice Olomouc (Fnol) - Onkologicka Klinika, Olomouc, Not set
University Hospital of Besancon, Besancon, Not set
Institut Bergonié Centre de Lutte Contre le Cancer (CLCC), Bordeaux Cedex, Not set
Centre de Lutte contre le Cancer - François Baclesse, Caen Cedex 5, Not set
Institut Paoli Calmettes, Marseille, Not set
Institut régional du Cancer de Montpellier - ICM Val d'Aurelle, MONTPELLIER Cedex 5, Not set
Pharmacy ICM Val d'Aurelle - Bat A - Rez-de-Jardin, MONTPELLIER Cedex 5, Not set
Centre de Lutte contre le Cancer (CLCC) - Centre Antoine Lacassagne, Nice Cedex 2, Not set
Hopital Europeen Georges Pompidou, Paris, Not set
Hospices Civils de Lyon, Pierre Benite, Not set
Unite de Coordination de la Biologie des Essais Cliniques, Strasbourg, Not set
Institut de Cancerologie Strasbourg Europe, Strasbourg, Not set
Institut Gustave Roussy, Villejuif Cedex, Not set
Athens Medical Center, Maroussi, Attikí
Bioclinic Thessalonikis Private Clinic Single Member S.A., Thessaloniki, Kentrikí Makedonía
Metropolitan General Hospital, Cholargos, Not set
Semmelweis Egyetem Urologiai Klinika, Budapest, Not set
Bacs-Kiskun Varmegyei Oktatokorhaz, Kecskemét, Not set
Rajiv Gandhi Cancer Institute And Research Centre, New Delhi, Delhi
Nirmal Hospital Pvt Ltd, Surat, Gujarat
Cancer Trials Cork, Cork, Not set
Tallaght University Hospital, Tallaght, Not set
Cork University Hospital, Wilton, Not set
Shaare Zedek Medical Center, Jerusalem, Other
Hadassah Medical Center, Jerusalem, Other
Sheba Medical Center., Ramat Gan, Other
Emek Medical Center, Afula, Not set
Soroka Medical Center, Be'er Sheva, Not set
Rambam Health Care Campus, Hafia, Not set
Meir Medical Center, Kefar Sava, Not set
Rabin Medical Center, Petach Tikva, Not set
Kaplan Medical Center, Rehovot, Not set
Tel Aviv Sourasky Medical Center, Tel Aviv, Not set
IRCCS Istituto Tumori Giovanni Paolo II, Bari, Apulia
Azienda Ospedaliera Cardinale Giovanni Panico, Tricase, Apulia
Oncologia Medica, Ospedale Civile S. Maria delle Croci, Ravenna, Emilia-romagna
Ospedale Policlinico San Martino, Genova, Liguria
Ospedale San Raffaele, Milano, Lombardy
Istituto Clinico Humanitas-Humanitas Cancer Center, Rozzano (Milano), Lombardy
IRCCS Istituto Clinico Humanitas, Rozzano, Milano
IRCCS - Ospedale San Raffaele, Milano, Milan
Azienda Sanitaria Locale Napoli 2 Nord, Giugliano in Campania, Naples
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Bari, Other
P.O. "S. Maria Delle Grazie" - Pozzuoli - ASL Napoli Nord 2, Pozzuoli (NA), Other
ASL-AT, Ospedale Cardinal Massaia di Asti, Asti, Piemonte
SOSD Farmacia Ospedaliera, Aviano, Pordenone
Centro di Riferimento Oncologico Di Aviano, Aviano, Pordenone
AUSL Romagna - Presidio Ospedale "Umberto I" di Lugo, Lugo, Ravenna
AUSL della Romagna - Ospedale degli infermi, Faenza, RA
Azienda Ospedaliero Universitaria Careggi, Firenze, Tuscany
Azienda Ospedaliera S. Maria di Terni, Terni, Umbria
ASL Asti - Ospedale Cardinal Massaia - S.C. Farmacia Ospedaliera, Asti, Not set
ASST Cremona Farmacia Ospedaliera, Cremona, Not set
U.O. Farmacia Ospedaliera a Politiche del Farmaco Az. Osp. Universitaria Careggi, Firenze, Not set
Ospedale Policlinico San Martino Farmacia, Genova, Not set
Istituto Nazionale Tumori IRCCS Fondazione G.Pascale Napoli Pascale, Napoli, Not set
SC Farmacia Ospedaliera C/O Istituto Nazionale Tumori IRCCS Fondazione G.Pascale Napoli Pascale, Napoli, Not set
Istituto Oncologico Veneto - IRCCS, Padova, Not set
Azienda Ospedaliera Universitaria Pisana Ospedale Santa Chiara, Pisa, Not set
Azienda Ospedaliera Universitaria Pisana, U.O. Farmacia Ospedaliera, Pisa, Not set
Policlinico Universitario Agostino Gemelli, Roma, Not set
Centro Ricerche Cliniche Di Verona Srl, Verona, Not set
Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Not set
Hirosaki University Hospital, Hirosaki, Aomori
Ehime University Hospital, Toon, Ehime
National Hospital Organization Kyushu Cancer Center, Fukuoka-shi, Fukuoka
Gunma Prefectural Cancer Center, Ota-Shi, Gunma
Kobe University Hospital, Kobe-shi, Hyogo
University of Tsukuba Hospital, Tsukuba, Ibaraki
Kagawa University Hospital, Kita-gun, Kagawa
Yokohama City University Medical Center, Yokohama, Kanagawa
Kanagawa Cancer Center, Yokohama, Kanagawa
University of Miyazaki Hospital, Miyazaki City, Miyazaki
Nara Medical University Hospital, Kashihara, Nara
Kindai University Hospital, Osakasayama-Shi, Osaka
Osaka University Hopsital, Suita-city, Osaka
Tokushima University Hospital, Tokushima-Shi, Tokushima
Keio University Hospital, Shinjuku-ku, Tokyo
Wakayama Medical University Hospital, Wakayama-shi, Wakayama
Yamaguchi University Hospital, Ube, Yamaguchi
Chiba Cancer Center, Chiba, Not set
National Hospital Organization Kumamoto Medical Center, Kumamoto, Not set
Osaka Prefectural Hospital Organization - Osaka International Cancer Institute, Osaka, Not set
Yamagata University Hospital, Yamagata, Not set
National Cancer Center, Goyang-si, Gyeonggi-do
CHA Bundang Medical Center, CHA University, Seongnam-si, Gyeonggi-do
The Catholic University of Korea, St. Vincent's Hospital, Suwon-si, Gyeonggi-do
Jeonbuk National University Hospital, Jeonju-si, Jeollabuk-do
Chonnam National University Hwasun Hospital, Hwasun-gun, Jeollanam-do
Wonkwang University Hospital, Iksan-si, Jeonlabuk-do
Inje University Haeundae Paik Hospital, Busan, Not set
Kosin University Gospel Hospital, Busan, Not set
Gachon University Gil Medical Center, Incheon, Not set
Seoul National University Bundang Hospital, Seongnam-si, Not set
Korea University Anam Hospital, Seoul, Not set
Kangbuk Samsung Hospital, Seoul, Not set
Severance Hospital Yonsei University Health System, Seoul, Not set
Asan Medical Center - Oncology, Seoul, Not set
Amphia Ziekenhuis, Breda, Noord-brabant
Haga Ziekenhuis, Den Haag, Zuid-holland
Antoni van Leeuwenhoek Apotheek,I-2, Amsterdam, Not set
Netherlands Cancer Institute/Antoni van Leeuwenhoek, Amsterdam, Not set
Rijnstate Hospital, Arnhem, Not set
Maastricht Universitair Medisch Centrum+, Maastricht, Not set
Radboud University Medical Center, Nijmegen, Not set
Akershus universitetssykehus HF, Lørenskog, Akershus
Avdeling for blod og kreft sykdommer. Stavanger universitetssykehus, Stavanger, Not set
Hospital Militar Central Coronel Luis Arias Schreiber, Lima, Not set
Hospital Maria Auxiliadora, Lima, Not set
Hospital de Braga, Sao Victor, Braga
Hospital de Braga, Braga, Not set
Centro Clinico Champalimaud, Lisboa, Not set
Hospital de Santa Maria - Centro Hospitalar Universitario Lisboa Norte, Lisboa, Not set
Champalimaud Clinical Center, Lisbon, Not set
Centro Hospitalar Universitário de São João, Porto, Not set
National University Hospital, Singapore, Not set
National University Cancer Institute, Singapore, Not set
National Cancer Centre Singapore, Singapore, Not set
Raffles Hospital, Singapore, Not set
Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, A Coruna
Farmacia Oncologica - Unidad de Ensayos Clinicos, Santiago de Compostela, A Coruna
Hospital Universitario Badajoz, Badajoz, A Coruña [LA Coruña]
Institut Catala d' Oncologia de Badalona - Hospital Universitari Germans Trias i Pujos, Badalona, Barcelona
Institut Catala d'Oncologia Badalona (ICO Badalona) - Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona
Institut Catala d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet), L'Hospitalet de Llobregat, Barcelona
Hospital de Cruzes, Barakaldo, Bizkaia
Hospital Universitario Marques de Valdecilla, Santander, Cantabria
Hospital Universitario Puerta de Hierro - Majadahonda, Majadahonda, Madrid
Infanta Cristina Hospital, Badajoz, Not set
Hospital Del Mar, Barcelona, Not set
Hospital Universitari Vall D Hebron, Barcelona, Not set
Hospital Universitari Vall d'Hebron, Barcelona, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau- Pharmacy, Barcelona, Not set
Hospital de La Santa Creu i Sant Pau, Barcelona, Not set
Unitat d'Assajos Clinics Servei de Farmacia, L'Hospitaler De Llobregat, Not set
Complejo Hospitalario Universitario Insular Materno-Infantil, Las Palmas de Gran Canaria, Not set
Hospital General Universitario Gregorio Maranon, Madrid, Not set
Hospital General Universitario Gregorio Maranon, Madrid, Not set
MD Anderson Cancer Center Madrid, Madrid, Not set
Hospital Universitario Ramon y Cajal, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Universitario La Paz: Servicio de Farmacia, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
HM Centro Integral Oncologico Clara Campal, Madrid, Not set
Hospital Universitario HM Sanchinarro, Madrid, Not set
Complejo Hospitalario Universitario de Ourense (CHOU), Ourense, Not set
Hospital Universitario Virgen Del Rocio, Sevilla, Not set
Consorcio Hospital General Universitario de Valencia (CHGUV), Valencia, Not set
Consorcio Hospital General Universitario de Valencia, Valencia, Not set
Hospital Universitario Miguel Servet, Zaragoza, Not set
Ryhov Hospital, Jonkoping, Not set
Karolinska University Hospital, Stockholm, Not set
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City, Not set
Chang Gung Memorial Hospital Kaohsiung Branch, Kaohsiung City, Not set
Kaohsiung Medical University Hospital, Kaohsiung, Not set
China Medical University Hospital - Pharmacy, Taichung, Not set
China Medical University Hospital, Taichung, Not set
Taichung Veterans General Hospital Clinical Trials Pharmacy, Taichung, Not set
Taichung Veterans General Hospital, Taichung, Not set
Chi Mei Hospital liouying, Tainan City, Not set
Clinical Trial Pharmacy, Department of Pharmacy, National Cheng Kung University Hospital, Tainan, Not set
National Cheng-Kung University Hospital, Tainan, Not set
National Taiwan University Hospital, Investigational Drug Service, Taipei, Not set
National Taiwan University Hospital, Taipei, Not set
NHS Greater Glasgow and Clyde (NHSGGC) - The Beatson West of Scotland Cancer Centre, Glasgow, Other
Barts Health NHS Trust Saint Bartholomews Hospital, London, Not set
Guy's and St Thomas' NHS Foundation Trust, London, Not set
Guy's and St Thomas' NHS Foundation, London, Not set
Conditions: Urothelial Carcinoma
A First-in-human Study to Learn How Safe BAY 3713372 is and How it Works in Participants With MTAP-deleted Solid Tumors
Recruiting
The study treatment, BAY 3713372, is under development to treat MTAP (methylthioadenosine phosphorylase)-deleted solid tumors. It is thought to work by blocking the protein arginine N-methyltransferase 5 (PRMT5). This may kill the MTAP-deleted cancer cells while sparing the normal cells.
The main objective of this first-in-human study is to check if BAY 3713372 is safe for further testing and find the dose that could be used to treat different cancer types that are also MTAP-deleted in future s... Read More
The study treatment, BAY 3713372, is under development to treat MTAP (methylthioadenosine phosphorylase)-deleted solid tumors. It is thought to work by blocking the protein arginine N-methyltransferase 5 (PRMT5). This may kill the MTAP-deleted cancer cells while sparing the normal cells.
The main objective of this first-in-human study is to check if BAY 3713372 is safe for further testing and find the dose that could be used to treat different cancer types that are also MTAP-deleted in future studies.
For this, the researchers will study and analyze:
* the number of participants who have adverse events after receiving different doses of BAY 3713372 and their severity.
* the number of participants who experience dose-limiting toxicities (DLTs) after receiving different doses of BAY 3713372, their severity and how often they happened. A DLT is a pre-defined medical problem caused by a specific dose of a drug that is too severe to continue using that dose.
* the total amount of BAY 3713372 in participants' blood (also called AUC) over time after single and multiple doses.
* the highest level of BAY 3713372 in participants' blood (also called Cmax) after single and multiple doses.
Other than the main objective, researchers will also check for the number of participants who show a response to treatment and how long they live without the cancer getting worse.
The study participants will receive BAY 3713372 (starting from low to high doses) in the study, to find the highest safe dose for further testing.
Participants may take the study treatment as long as they benefit from the treatment without any severe medical problems.
Participants will visit the study site:
* at least twice before the treatment starts
* multiple times when they start taking the treatment
* once after 30 days of receiving the last dose and every 9 weeks after that until the cancer worsens, or the participant stops for any other reason
During the study, the doctors and their study team will:
* check participants' health by performing tests such as blood and urine tests, and checking heart health using an electrocardiogram
* check if the participants' cancer has grown and/or spread using computed tomography (CT) or magnetic resonance imaging (MRI) and, if needed, bone scan
* take tumor samples
The study doctors and their team will contact the participants every 3 months until 2 years after the last participant's last dose or the end of the study to learn about the participant's health. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Sarah Cannon - HCA HealthONE Presbyterian St. Luke's - Oncology Department, Denver, Colorado +34 locations
Sarah Cannon - HCA HealthONE Presbyterian St. Luke's - Oncology Department, Denver, Colorado
Sarah Cannon Research Institute at Florida Cancer Specialists- Lake Nona, Orlando, Florida
START | Midwest, Grand Rapids, Michigan
SCRI Oncology Partners, Nashville, Tennessee
NEXT Dallas - Oncology Department, Irving, Texas
START | San Antonio, San Antonio, Texas
Chris O'Brien Lifehouse, Camperdown, New South Wales
Concord Repatriation General Hospital (CRGH) (Concord Hospital) - Concord Cancer Centre, Concord, New South Wales
Ghent University Hospital | Drug Research Unit Department, Gent, Not set
Centre Hospitalier Universitaire (CHU) de Liege - Domaine Universitaire du Sart Tilman - Medical Oncology, Liege, Not set
Beijing Cancer Hospital - Oncology Department, Beijing, Beijing
Tongji Hosp. of Tongji Med Coll, Huazhong Uni of Sci & Tech., Wuhan, Hubei
Masarykova Univerzita - Masarykuv Onkologicky Ustav (MOU) - Klinika Komplexni Onkologicke Pece (KKOP), Brno, Not set
Fakultní Nemocnice Olomouc, Olomouc, Not set
Rigshospitalet - Kræftbehandling, Copenhagen, Not set
Odense University Hospital - Oncology Department, Odense C, Not set
Fondazione IRCCS Istituto Nazionale dei Tumori - S. C. Oncologia Medica 1, Milano, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - UOC Fase I, Roma, Not set
Humanitas Mirasole S.p.A. - Oncologia Medica ed Ematologia, Rozzano, Not set
Shizuoka Cancer Center, Sunto, Shizuoka
National Cancer Center Hospital, Chuo-ku, Tokyo
The Cancer Institute Hospital of JFCR, Koto-ku, Tokyo
Nederlands Kanker Instituut, Amsterdam, Not set
Erasmus Medisch Centrum, Rotterdam, Not set
National University Hospital Medical Centre, Singapore, Not set
National Cancer Center Singapore - Oncology Department, Singapore, Not set
Hospital Hm Nou Delfos - Oncologia, Barcelona, Not set
Hospital Universitari Vall d'Hebron- Oncology Service, Barcelona, Not set
The START Center for Cancer Care - Mardrid-Fundacion Jimenez Diaz (START Madrid-FJD), Madrid, Not set
Instituto de Investigacion Biomedica de Malaga (IBIMA) - sede Hospital Universitario Virgen de la Victoria (HUVV), Malaga, Not set
NEXT Oncology- Next Madrid, Pozuelo de Alarcón, Not set
Sahlgrenska Universitetssjukhuset - Klinisk prövningsenhet Fas I/FIH, Göteborg, Not set
Karolinska Universitetssjukhuset - Fas I-enheten Solna CKC, Stockholm, Not set
The Royal Marsden NHS Foundation Trust | Sutton - Oak Foundation Drug Development Unit, London, Greater London
The Christie NHS Foundation Trust | Christie Hospital - Experimental Cancer Medicine Team, Manchester, Not set
Conditions: MTAP-deleted Solid Tumors
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Recruiting
The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone receptor positive/human epidermal growth factor receptor-2 negative (HR+/HER2-) unresectable locally advanced, or metastatic, breast cancer.
The primary hypotheses are that sacituzumab tirumotecan as a single agent and sacituzumab tirumotecan plus pembrolizumab are superior to TPC with respect to progr... Read More
The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone receptor positive/human epidermal growth factor receptor-2 negative (HR+/HER2-) unresectable locally advanced, or metastatic, breast cancer.
The primary hypotheses are that sacituzumab tirumotecan as a single agent and sacituzumab tirumotecan plus pembrolizumab are superior to TPC with respect to progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) by blinded independent central review (BICR) in all participants. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Ironwood Cancer & Research Centers ( Site 0066), Chandler, Arizona +241 locations
Ironwood Cancer & Research Centers ( Site 0066), Chandler, Arizona
Banner MD Anderson Cancer Center-Oncology ( Site 0004), Gilbert, Arizona
Providence Medical Foundation-Oncology ( Site 0020), Fullerton, California
Moores Cancer Center ( Site 0059), La Jolla, California
Cancer and Blood Specialty Clinic ( Site 0001), Los Alamitos, California
University of Colorado Anschutz Medical Campus ( Site 0061), Aurora, Colorado
UCHealth Cherry Creek Medical Center ( Site 0094), Denver, Colorado
University of Colorado Health - Highlands Ranch Hospital ( Site 0095), Highlands Ranch, Colorado
Yale Cancer Center ( Site 0060), New Haven, Connecticut
Stamford Hospital ( Site 0049), Stamford, Connecticut
AdventHealth Altamonte Springs ( Site 0021), Altamonte Springs, Florida
University of Florida College of Medicine ( Site 0063), Gainesville, Florida
Orlando Health Cancer Institute ( Site 0011), Orlando, Florida
Archbold Memorial Hospital-Lewis Hall Singletary Oncology Center ( Site 0032), Thomasville, Georgia
University of Chicago Medical Center ( Site 0067), Chicago, Illinois
Saint Elizabeth Medical Center Edgewood-Cancer Care Center ( Site 0053), Edgewood, Kentucky
Mary Bird Perkins Cancer Center-Breast & GYN Pavilion ( Site 0042), Baton Rouge, Louisiana
Greenebaum Comprehensive Cancer Center ( Site 0036), Baltimore, Maryland
Mercy Medical Center - Baltimore-Medical Oncology and Hematology ( Site 0028), Baltimore, Maryland
Holy Cross Hospital ( Site 0073), Silver Spring, Maryland
Dana-Farber Cancer Institute-Breast Oncology Center ( Site 0037), Boston, Massachusetts
Henry Ford Health ( Site 0002), Detroit, Michigan
Saint Luke's Cancer Institute ( Site 0027), Kansas City, Missouri
Washington University School of Medicine ( Site 0076), Saint Louis, Missouri
Laura and Isaac Perlmutter Cancer Center-Hematology and Oncology ( Site 0068), New York, New York
Hematology Oncology Associates of Rockland ( Site 0054), Nyack, New York
Stony Brook University-Cancer Center ( Site 0034), Stony Brook, New York
Levine Cancer Institute ( Site 0014), Charlotte, North Carolina
Zangmeister Cancer Center ( Site 7000), Columbus, Ohio
Providence Portland Medical Center ( Site 0044), Portland, Oregon
Providence St. Vincent Medical Center ( Site 0081), Portland, Oregon
Thomas Jefferson University - Clinical Research Institute ( Site 0056), Philadelphia, Pennsylvania
Texas Oncology-Dallas Presbyterian Hospital ( Site 8000), Dallas, Texas
The Center for Cancer and Blood Disorders ( Site 0041), Fort Worth, Texas
Texas Oncology - San Antonio ( Site 8002), San Antonio, Texas
The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center ( Site 0057), Tyler, Texas
Inova Schar Cancer Institute ( Site 0025), Fairfax, Virginia
Bon Secours St. Francis Medical Center-Oncology Research ( Site 0015), Midlothian, Virginia
VCU Health Adult Outpatient Pavillion ( Site 0070), Richmond, Virginia
Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 8001), Roanoke, Virginia
University Hospital and UW Health Clinics-Carbone Cancer Center ( Site 0040), Madison, Wisconsin
Instituto Alexander Fleming-Alexander Fleming ( Site 0382), Ciudad Autónoma de Buenos Aires, Caba
Fundacion Estudios Clinicos-Oncology ( Site 0384), Rosario, Santa Fe
Hospital Aleman-Oncology ( Site 0386), Buenos Aires, Not set
Centro de Educación Médica e Investigaciones clínicas "Dr. Norberto Quirno" (CEMIC) ( Site 0383), Buenos Aires, Not set
Hospital Italiano de Córdoba ( Site 0385), Cordoba, Not set
Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0387), La Rioja, Not set
Macquarie University-MQ Health Clinical Trials Unit ( Site 2002), Macquarie University, New South Wales
Westmead Hospital ( Site 2000), Westmead, New South Wales
Frankston Hospital-Oncology and Haematology ( Site 2003), Frankston, Victoria
Fiona Stanley Hospital-Medical Oncology ( Site 2004), Murdoch, Western Australia
Institut Jules Bordet-Medicine Oncology ( Site 1104), Anderlecht, Bruxelles-Capitale, Region De
Cliniques universitaires Saint-Luc-Medical Oncology ( Site 1103), Brussels, Bruxelles-Capitale, Region De
Jessa Ziekenhuis-Limburgs Oncologisch Centrum ( Site 1105), Hasselt, Limburg
AZ Maria Middelares-IKG ( Site 1106), Gent, Oost-Vlaanderen
Université Catholique de Louvain-Namur - Centre Hospitalier -Oncology ( Site 1107), Namur, Not set
Oncoclínica Oncologistas Associados-Clinical Research ( Site 0407), Teresina, Piaui
Hospital Moinhos de Vento ( Site 0403), Porto Alegre, Rio Grande Do Sul
Hospital do Câncer Mãe de Deus ( Site 0404), Porto Alegre, Rio Grande Do Sul
Instituto de Oncologia Saint Gallen ( Site 0412), Santa Cruz do Sul, Rio Grande Do Sul
Instituto do Câncer Brasil - Unidade Taubaté ( Site 0408), Taubaté, Sao Paulo
IBCC - Núcleo de Pesquisa e Ensino ( Site 0401), Sao Paulo, Not set
BC Cancer Surrey ( Site 0315), Surrey, British Columbia
Southlake Regional Health Centre ( Site 0311), Newmarket, Ontario
Princess Margaret Cancer Centre ( Site 0310), Toronto, Ontario
CIUSSS de l'Est-de-l'Île-de-Montréal ( Site 0301), Montreal, Quebec
Jewish General Hospital ( Site 0303), Montreal, Quebec
Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski ( Site 0308), Rimouski, Quebec
CHU de Quebec Universite Laval - Hopital du Saint-Sacrement ( Site 0302), Quebec, Not set
Oncovida ( Site 0453), Santiago., Region M. De Santiago
Clínica RedSalud Vitacura ( Site 0455), Santiago., Region M. De Santiago
FALP-UIDO ( Site 0451), Santiago, Region M. De Santiago
Pontificia Universidad Catolica de Chile ( Site 0454), Santiago, Region M. De Santiago
Bradfordhill ( Site 0452), Santiago, Region M. De Santiago
Bradford Hill Norte ( Site 0456), Antofagasta, Not set
Fundacion Colombiana de Cancerología Clinica Vida ( Site 0506), Medellín, Antioquia
Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0501), Valledupar, Cesar
IMAT S.A.S ( Site 0502), Monteria., Cordoba
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0507), Bogota, Distrito Capital De Bogota
Fundación Valle del Lili ( Site 0508), Cali, Valle Del Cauca
CIMCA ( Site 0551), San José, San Jose
Hospital Metropolitano - Sede Lindora ( Site 0550), Santa Ana, San Jose
ICIMED ( Site 0552), San Jose, Not set
Nemocnice Ceske Budejovice-Onkologicke oddeleni ( Site 1138), Ceske Budejovice, Jihocesky Kraj
Fakultni nemocnice Ostrava-Klinika onkologicka ( Site 1134), Ostrava-Poruba, Moravskoslezsky Kraj
Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 1132), Olomouc, Olomoucky Kraj
Fakultni nemocnice v Motole-Onkologicka klinika 2. LF UK a FN Motol ( Site 1136), Praha, Praha 5
Fakultni nemocnice Kralovske Vinohrady-Onkologická klinika ( Site 1135), Praha 10, Not set
Rigshospitalet ( Site 1180), Copenhagen, Hovedstaden
Nordsjællands Hospital - Hillerød ( Site 1184), Hillerod, Hovedstaden
Næstved Sygehus ( Site 1182), Naestved, Sjaelland
Odense Universitetshospital ( Site 1181), Odense C, Syddanmark
Vejle Sygehus ( Site 1183), Vejle, Syddanmark
Centre François Baclesse ( Site 1250), Caen, Calvados
Centre de Cancérologie du Grand Montpellier ( Site 1244), Montpellier, Languedoc-Roussillon
Hôpital privé du Confluent SAS-Service d'oncologie médicale ( Site 1242), Nantes, Loire-Atlantique
Pitie Salpetriere University Hospital ( Site 1249), Paris, Orne
Hopital Prive Jean Mermoz-Oncology ( Site 1246), Lyon, Rhone-Alpes
Centre Hospitalier Universitaire de Poitiers-Pôle régional de cancérologie ( Site 1243), Poitiers, Vienne
Institut Curie-Oncology medical Department ( Site 1240), Paris, Not set
SRH Wald-Klinikum Gera-Zentrum für klinische Studien ( Site 1315), Gera, Thuringen
Helios Klinikum Berlin-Buch-Klinik für Gynäkologie und Geburtshilfe ( Site 1314), Berlin, Not set
Errikos Dunant Hospital Center ( Site 1348), Athens, Attiki
Aretaieio Hospital Oncology Unit ( Site 1345), Athens, Attiki
Hygeia Hospital ( Site 1346), Marousi, Attiki
University General Hospital of Larissa ( Site 1343), Larissa, Thessalia
Agios Loukas Clinic ( Site 1347), Thessaloniki, Not set
European Interbalkan Medical Center ( Site 1341), Thessaloniki, Not set
Queen Mary Hospital ( Site 2040), Hksar, Not set
Prince of Wales Hospital ( Site 2041), Shatin, Not set
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Onkoterápiás Klinika ( Site 1379), Szeged, Csongrad
Somogy Vármegyei Kaposi Mór Oktató Kórház-Oncology center ( Site 1371), Kaposvár, Somogy
Zala Vármegyei Szent Rafael Kórház-Onkológiai osztály ( Site 1372), Zalaegerszeg, Zala
Semmelweis Egyetem-Belgyógyászati és Onkológiai Klinika ( Site 1381), Budapest, Not set
Budapesti Uzsoki Utcai Kórház-Onkoradiológiai Osztály ( Site 1373), Budapest, Not set
Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 1375), Debrecen, Not set
All India Institute of Medical Sciences ( Site 2051), New Delhi, Delhi
Rajiv Gandhi Cancer Institute And Research Centre-Department of Clinical Research ( Site 2052), New Delhi, Delhi
Tata Memorial Hospital-Medical Oncology ( Site 2053), Mumbai, Maharashtra
Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute-Centre for cancer ( Site 2056), Mumbai, Maharashtra
Bon Secours Cork Hospital ( Site 1422), Cork, Not set
St. Vincent's University Hospital-Medical Oncology Research Department ( Site 1420), Dublin, Not set
Mater Misericordiae University Hospital-Clinical Trials Research Unit ( Site 1423), Dublin, Not set
Rambam Health Care Campus-Oncology Division ( Site 1452), Haifa, Not set
Hadassah Medical Center ( Site 1451), Jerusalem, Not set
Rabin Medical Center ( Site 1453), Petah Tikva, Not set
Sheba Medical Center ( Site 1450), Ramat Gan, Not set
IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori" ( Site 1480), Meldola, Forli-Cesena
CRO-IRCCS ( Site 1478), Aviano, Friuli-Venezia Giulia
Istituto Europeo di Oncologia IRCCS-Divisione di Senologia Medica ( Site 1475), Milano, Lombardia
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1472), Milan, Lombardia
Istituto Clinico Humanitas ( Site 1476), Rozzano, Milano
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 1474), Bologna, Not set
Ospedale San Martino ( Site 1479), Genova, Not set
Ospedale San Raffaele-Oncologia Medica ( Site 1471), Milano, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 1477), Roma, Not set
Nagoya City University Hospital ( Site 2474), Nagoya, Aichi
Hokkaido University Hospital ( Site 2460), Sapporo, Hokkaido
Tokai University Hospital ( Site 2473), Isehara, Kanagawa
St. Marianna University Hospital ( Site 2465), Kawasaki, Kanagawa
Kitasato University Hospital ( Site 2471), Sagamihara, Kanagawa
Kanagawa Cancer Center ( Site 2472), Yokohama, Kanagawa
Mie University Hospital ( Site 2483), Tsu, Mie
Tohoku University Hospital ( Site 2482), Sendai, Miyagi
The University of Osaka Hospital ( Site 2476), Suita, Osaka
Saitama Medical University International Medical Center ( Site 2462), Hidaka, Saitama
Juntendo University Hospital ( Site 2468), Bunkyo, Tokyo
Cancer Institute Hospital of JFCR ( Site 2464), Koto, Tokyo
Showa Medical University Hospital ( Site 2466), Shinagawa, Tokyo
Tokyo Medical University Hospital ( Site 2467), Shinjuku, Tokyo
National Center for Global Health and Medicine ( Site 2469), Shinjuku, Tokyo
Fukushima Medical University Hospital ( Site 2461), Fukushima, Not set
Gifu University Hospital ( Site 2486), Gifu, Not set
Hiroshima City Hiroshima Citizens Hospital ( Site 2478), Hiroshima, Not set
Social medical corporation Hakuaikai Sagara Hospital ( Site 2481), Kagoshima, Not set
Kumamoto University Hospital ( Site 2480), Kumamoto, Not set
Kyoto University Hospital ( Site 2475), Kyoto, Not set
Okayama University Hospital ( Site 2485), Okayama, Not set
Osaka International Cancer Institute ( Site 2477), Osaka, Not set
Seoul National University Hospital-Internal Medicine ( Site 2353), Seoul, Not set
Severance Hospital, Yonsei University Health System-Medical oncology ( Site 2350), Seoul, Not set
Asan Medical Center-Department of Oncology ( Site 2352), Seoul, Not set
Samsung Medical Center-Division of Hematology/Oncology ( Site 2351), Seoul, Not set
Hospital Sultan Ismail ( Site 2153), Johor Bahru, Johor
Sarawak General Hospital ( Site 2154), Kuching, Sarawak
Pantai Hospital Kuala Lumpur ( Site 2151), Kuala Lumpur, Not set
Health Pharma Professional Research S.A. de C.V: ( Site 0598), Ciudad de México, Distrito Federal
Grupo Médico ASSET-Clinical Research ( Site 0596), Mexico City, Distrito Federal
CIO - Centro de Inmuno-Oncología de Occidente ( Site 0592), Guadalajara, Jalisco
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Servicio de Oncología ( Site 0590), Monterrey, Nuevo Leon
CENTRO MEDICO ZAMBRANO HELLION-Centro de Cáncer de Mama ( Site 0595), San Pedro Garza Garcia, Nuevo Leon
Ziekenhuis Rijnstate-Rijnstate Centrum Oncologisch Onderzoek ( Site 1524), Arnhem, Gelderland
Maastricht UMC+-Medical Oncology ( Site 1522), Maastricht, Limburg
Amphia Ziekenhuis, locatie Breda Molengracht-oncologie ( Site 1523), Breda, Noord-Brabant
Catharina Ziekenhuis ( Site 1526), Eindhoven, Noord-Brabant
Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL)-medical oncology ( Site 1520), Amsterdam, Noord-Holland
Isala, locatie Zwolle ( Site 1525), Zwolle, Overijssel
Meander Medisch Centrum ( Site 1521), Amersfoort, Utrecht
Auckland City Hospital ( Site 2031), Auckland, Not set
Clinica Vallesur - AUNA ( Site 0652), Arequipa, Ariqipa
Hospital Militar Central Luis Arias Schereiber ( Site 0651), Jesús María, Lima
Oncosalud ( Site 0650), Lima, Muni Metro De Lima
IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0653), Lima, Not set
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1582), Bydgoszcz, Kujawsko-pomorskie
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1584), Siedlce, Mazowieckie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworów Piersi i Chirurgii ( Site 1580), Warszawa, Mazowieckie
Mazowiecki Szpital Onkologiczny ( Site 1581), Wieliszew, Mazowieckie
Mrukmed-Mrukmed ( Site 1592), Rzeszow, Podkarpackie
Bialostockie Centrum Onkologii ( Site 1585), Bialystok, Podlaskie
Szpitale Pomorskie Sp. z o. o.-Oddział Onkologii Klinicznej ( Site 1593), Gdynia, Pomorskie
Narodowy Instytut Onkologii - Oddzial w Gliwicach-Centrum Diagnostyki i Leczenia Chorob Piersi ( Site 1590), Gliwice, Slaskie
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Onkologii Klinicznej, Dzial Ch ( Site 1595), Kielce, Swietokrzyskie
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1583), Koszalin, Zachodniopomorskie
Zachodniopomorskie Centrum Onkologii ( Site 1588), Szczecin, Zachodniopomorskie
Unidade Local de Saude Amadora/Sintra - Hospital Prof Dr Fernando Fonseca ( Site 1663), Lisbon, Lisboa
Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 1661), Lisboa, Not set
Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 1662), Porto, Not set
Puerto Rico Medical Research Center LLC ( Site 0675), Hato Rey, Not set
UPR Comprehensive Cancer Center-Comprehensive Cancer Center Hospital ( Site 0677), San Juan, Not set
Spitalul Clinic Filantropia ( Site 1703), București, Bucuresti
SC Radiotherapy Center Cluj SRL-Oncologie Medicala ( Site 1702), Florești, Cluj
Centrul Medical Neolife- Baneasa ( Site 1704), Bucuresti, Not set
Institutul Oncologic Cluj ( Site 1701), Cluj, Not set
National University Hospital ( Site 2250), Singapore, Central Singapore
Mount Alvernia ICON Cancer Center ( Site 2251), Singapore, North East
CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE ( Site 2905), Port Elizabeth, Eastern Cape
Curo Oncology ( Site 2908), Pretoria, Gauteng
Sandton Oncology Medical Group (Pty) Ltd ( Site 2911), Sandton, Gauteng
Cancercare Rondebosch Oncology-Clinical trials ( Site 2904), Rondebosch, Western Cape
HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID ( Site 1758), Pozuelo de Alarcon, Madrid
HOSPITAL CLINICO DE VALENCIA-Oncology ( Site 1752), Valencia, Valenciana, Comunitat
Hospital Universitari Vall d'Hebron-Oncology ( Site 1750), Barcelona, Not set
Hospital Universitario Reina Sofia-Oncologia Medica ( Site 1754), Cordoba, Not set
Hospital Beata María Ana-oncology ( Site 1755), Madrid, Not set
HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 1756), Madrid, Not set
Hospital Universitario Virgen Macarena ( Site 1757), Sevilla, Not set
Karolinska Universitetssjukhuset Solna ( Site 1801), Stockholm, Stockholms Lan
Akademiska sjukhuset ( Site 1802), Uppsala, Uppsala Lan
Södra Älvsborgs Sjukhus Borås ( Site 1803), Borås, Vastra Gotalands Lan
University Hospital Basel-Gynecology & Gynecologic Oncology ( Site 1844), Basel, Basel-Stadt
Spital Thun ( Site 1840), Thun, Berne
Brust-Zentrum ( Site 1841), Zürich, Zurich
Changhua Christian Hospital ( Site 2410), Changhua, Not set
Chang Gung Memorial Hospital at Kaohsiung-Oncology and Hematology ( Site 2413), Kaohsiung, Not set
National Cheng Kung University Hospital-Surgery ( Site 2411), Tainan, Not set
National Taiwan University Hospital-Oncology ( Site 2415), Taipei, Not set
Mackay Memorial Hospital ( Site 2412), Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch-General Surgery ( Site 2414), Taoyuan, Not set
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi ( Site 1878), Yenimahalle, Ankara
Medipol Mega Universite Hastanesi-oncology ( Site 1875), Stanbul, Istanbul
Adana Medical Park Seyhan Hastanesi-Medikal Onkoloji ( Site 1876), Adana, Not set
Hacettepe Universite Hastaneleri-oncology hospital ( Site 1870), Ankara, Not set
Memorial Ankara Hastanesi-Medical Oncology ( Site 1874), Ankara, Not set
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1871), Ankara, Not set
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1872), Istanbul, Not set
Samsun Medical Park Hastanesi-medical oncology ( Site 1873), Samsun, Not set
North West Cancer Centre ( Site 1944), Londonderry, Derry And Strabane
The Royal Cornwall Hospital ( Site 1943), Truro, England
St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 1940), London, London, City Of
University College London Hospital-Cancer Clinical Trials Unit ( Site 1942), London, London, City Of
Blackpool Victoria Hospital ( Site 1941), Blackpool, Not set
City Hospital, Nottingham University Hospitals NHS Trust ( Site 1945), Nottingham, Not set
Conditions: Breast Neoplasms
A Study to Learn About the Study Medicine Called PF-08046031 in Advanced Melanoma and Other Solid Tumors
Recruiting
This study will test the safety of a drug called PF-08046031 in participants with melanoma and other solid tumors that have no current approved treatment or have spread through the body. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease. The study will have 3 parts. Part A and B of the study will find out how much PF-08046031 should be given to participants. Part C will use the information from Parts A and B to see if... Read More
This study will test the safety of a drug called PF-08046031 in participants with melanoma and other solid tumors that have no current approved treatment or have spread through the body. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease. The study will have 3 parts. Part A and B of the study will find out how much PF-08046031 should be given to participants. Part C will use the information from Parts A and B to see if PF-08046031 is safe and if it works to treat solid tumor cancers. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: The Angeles Clinic and Research Institue, A Cedars-Sinai Affiliate, Los Angeles, California +12 locations
The Angeles Clinic and Research Institue, A Cedars-Sinai Affiliate, Los Angeles, California
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California
UCSF Medical Center, Investigational Pharmacy, San Francisco, California
The Angeles Clinic and Research Institue, A Cedars-Sinai Affiliate (Emergency Back-up only), Santa Monica, California
Sarah Cannon Research Institute at HealthONE - SCRI - PPDS, Denver, Colorado
Florida Cancer Specialists, Orlando, Florida
Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando, Florida
UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
UPMC Shadyside Hospital, Pittsburgh, Pennsylvania
Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [barcelona]
Karolinska Universitetssjukhuset Solna, Solna, Stockholms LÄN [se-01]
Sarah Cannon Research Institute UK, London, London, CITY OF
The Royal Marsden NHS Foundation Trust, Sutton, Not set
Conditions: Malignant Melanoma, Melanoma, Metastatic Melanoma, Solid Tumors
A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
Recruiting
The purpose of this study is to evaluate that milvexian is superior to placebo, in addition to standard-of-care, in reducing the risk of major adverse cardiovascular event (MACE) (the composite of cardiovascular \[CV\] death, myocardial infarction \[MI\], and ischemic stroke).
The purpose of this study is to evaluate that milvexian is superior to placebo, in addition to standard-of-care, in reducing the risk of major adverse cardiovascular event (MACE) (the composite of cardiovascular \[CV\] death, myocardial infarction \[MI\], and ischemic stroke). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Advanced Cardiovascular, LLC, Alexander City, Alabama +997 locations
Advanced Cardiovascular, LLC, Alexander City, Alabama
SORRA Research, Birmingham, Alabama
Ascension St. Vincent's Health System, Birmingham, Alabama
IMC-Diagnostic and Medical Clinic, Mobile, Alabama
Cardiology Associates of Mobile Inc, Mobile, Alabama
Mercy Gilbert Medical Center, Gilbert, Arizona
Valleywise Health Medical Center, Phoenix, Arizona
HonorHealth Neurology, Scottsdale, Arizona
Arkansas Heart Hospital, Little Rock, Arkansas
Bakersfield Memorial Hospital, Bakersfield, California
Mission Cardiovascular Research Institute, Fremont, California
Radin Cardiovascular Medical Group, Newport Beach, California
Valley Clinical Trials, Inc., Northridge, California
Stanford University School of Medicine, Palo Alto, California
VA Palo Alto Healthcare System, Palo Alto, California
Huntington Hospital, Pasadena, California
The Cardiovascular Center, Redding, California
University Of California San Diego, San Diego, California
San Diego Cardiac Center, San Diego, California
VA San Diego Health Care System, San Diego, California
UCLA, Santa Monica, California
NorthBay Clinical Research, LLC, Santa Rosa, California
Ramin Manshadi, MD, Stockton, California
South Denver Cardiology Associates PC, Littleton, Colorado
Nuvance Health Medical Practices Cardiology Danbury, Danbury, Connecticut
Cardiology Associates of Fairfield County, P.C., Stamford, Connecticut
George Washington University Medical Center, Washington, District of Columbia
FWD Clinical Research, Boca Raton, Florida
Clearwater Cardiovascular Consultants, Clearwater, Florida
Holy Cross Hospital Inc., Fort Lauderdale, Florida
Integrative Research Associates, Fort Lauderdale, Florida
University of Florida Health Jacksonville, Gainesville, Florida
Inpatient Research Clinic LLC, Hialeah, Florida
Shands Jacksonville Medical Center Inc dba UF Health Jacksonville, Jacksonville, Florida
Cardiology Partners Clinical Research Institute, Loxahatchee Groves, Florida
Baptist Hospital of Miami, Miami, Florida
Advanced Research for Health Improvement, Naples, Florida
Amavita Clinical Research (Dr. Pedro Martinez-Clark), North Miami Beach, Florida
South Florida Research Solutions LLC, Pembroke Pines, Florida
Coastal Cardiology Consultants, Safety Harbor, Florida
Cardiovascular Center of Sarasota, Sarasota, Florida
Tampa Cardiovascular Interventions and Research, Tampa, Florida
Interventional Cardiac Consultants, Trinity, Florida
Cardiology Partners Clinical Research Institute, Wellington, Florida
Grady Memorial Hospital, Atlanta, Georgia
Atlanta Clinical Research Center, Cartersville, Georgia
Northeast Georgia Heart Center, Gainesville, Georgia
Cardiovascular Consultants of South Georgia LLC, Thomasville, Georgia
Kootenai Medical Center, Coeur d'Alene, Idaho
Insight Hospital and Medical Center Chicago, Chicago, Illinois
Illinois Heart and Vascular Foundation, Chicago, Illinois
Advocate Heart Institute, Downers Grove, Illinois
Clinical Investigation Specialists, Inc., Gurnee, Illinois
Essential Concepts Research Solutions, Palos Hills, Illinois
OSF HealthCare Cardiovascular Institute, Peoria, Illinois
Methodist Medical Center of Illinois, Peoria, Illinois
Prairie Cardiovascular Consultants, Ltd., Springfield, Illinois
Carle Foundation Hospital, Urbana, Illinois
Midwest Cardiovascular Research Foundation, Elkhart, Indiana
Northern Indiana Research Alliance, Fort Wayne, Indiana
IU Health Ball Memorial Hospital, Muncie, Indiana
Reid Health, Richmond, Indiana
Health Midwest Ventures Group, Inc d b a HCA MidAmerica Division, LLC, Overland Park, Kansas
University of Louisville, Louisville, Kentucky
Norton Cardiovascular Associates, Louisville, Kentucky
Cambridge Medical Trials, Alexandria, Louisiana
Cardiovascular Institute of the South, Houma, Louisiana
Ochsner Clinic And Hospital, New Orleans, Louisiana
Louisiana Heart Center, Slidell, Louisiana
Monroe Research LLC, West Monroe, Louisiana
Eastern Maine Medical Center Northeast Cardiology Associates, Bangor, Maine
Johns Hopkins University School of Medicine, Baltimore, Maryland
Suburban Hospital, Bethesda, Maryland
Captiol Cardiology Associates, Lanham, Maryland
Shady Grove Office, Rockville, Maryland
Tidal Health Peninsula Regional Inc., Salisbury, Maryland
Pentucket Medical Associates, Haverhill, Massachusetts
University of Michigan, Ann Arbor, Michigan
St. Joseph Mercy Oakland, Bloomfield Hills, Michigan
AAMRC, Flint, Michigan
Jackson Heart Clinic, Jackson, Michigan
Sparrow Clinical Research Institute, Lansing, Michigan
St. Luke's Cardiology Associates, Duluth, Minnesota
HealthEast Medical Research Institute, Saint Paul, Minnesota
Mercy Medical Research Institute, Chesterfield, Missouri
The Curators of the University of Missouri on behalf of University of Missouri Health Care, Columbia, Missouri
North Kansas City Hospital, Kansas City, Missouri
Spectrum Clinical Research, Kansas City, Missouri
Saint Louis University, Saint Louis, Missouri
Cox Health, Springfield, Missouri
Bryan LGH Heart Institute, Lincoln, Nebraska
Methodist Physicians Clinic Heart Consultants, Omaha, Nebraska
University Medical Center of Southern Nevada, Las Vegas, Nevada
Ash Research Clinic, Brick, New Jersey
Englewood Health, Englewood, New Jersey
Newark Beth Israel Medical Center, Newark, New Jersey
Atlanticare Regional Medical Center, Pomona, New Jersey
Cardio Metabolic Institute, Somerset, New Jersey
Cardiac Care & Vascular Medicine, PLLC, Bronx, New York
Buffalo General Medical Center, Buffalo, New York
Jamaica Hospital Medical Center, Jamaica, New York
Columbia University Medical Center, New York, New York
Weil Cornell University, New York, New York
Weill Cornell Medicine, New York, New York
Hudson Valley Cardiovascular Practice, PC, Poughkeepsie, New York
Westchester Medical Center, Valhalla, New York
Clinical Trials of America, Cary, North Carolina
UNC School of Medicine, Chapel Hill, North Carolina
The Moses H. Cone Memorial Hospital, Greensboro, North Carolina
Atrium Health Wake Forest Baptist, High Point, North Carolina
Clinical Trials of America, Lenoir, North Carolina
Novant Health, Matthews, North Carolina
Rex Hospital, Raleigh, North Carolina
Sanford Cardiology, Sanford, North Carolina
Trinity Medical Group, Minot, North Dakota
Summa Health System, Akron, Ohio
University of Cincinnati, Cincinnati, Ohio
Metro Health Hospital, Cleveland, Ohio
Ohio Health, Columbus, Ohio
Kettering Medical Center, Kettering, Ohio
The Heart House, Springfield, Ohio
Ascension Medical Group - St. John Clinic Infectious Disease, Bartlesville, Oklahoma
South Oklahoma Heart Research, Oklahoma City, Oklahoma
St John Health System Inc, Tulsa, Oklahoma
Advanced Cardiac Care, Bethlehem, Pennsylvania
Chambersburg Hospital, Chambersburg, Pennsylvania
Hamot Medical Center, Erie, Pennsylvania
UPMC Pinnacle Health, Harrisburg, Pennsylvania
St. Mary Medical Center, Langhorne, Pennsylvania
Penn Presbyterian Medical Center, Philadelphia, Pennsylvania
Lankenau Institute for Medical Research, Wynnewood, Pennsylvania
AnMed Health, Anderson, South Carolina
Prisma Health, Greenville, South Carolina
St. Francis Physician Services, Inc, DBA Upstate Cardiology Research, Greenville, South Carolina
Carolina Cardiology Associates, Rock Hill, South Carolina
Monument Health Clinical Research, Rapid City, South Dakota
Erlanger Health System, Chattanooga, Tennessee
Apex Cardiology, Jackson, Tennessee
Ascension Saint Thomas West Hospital, Nashville, Tennessee
Vanderbilt University, Nashville, Tennessee
Parkway Cardiology Associates PC, Oak Ridge, Tennessee
Amarillo Heart Clinical Research Institute, Amarillo, Texas
PharmaTex Research, Amarillo, Texas
Med Research, Inc., El Paso, Texas
Texas Tech University Health Sciences Center-El Paso, El Paso, Texas
Baylor Scott and White Research Institute, Fort Worth, Texas
East Texas Cardiology, PA, Houston, Texas
Physician Research Network, Houston, Texas
Vital Heart and Vein, Humble, Texas
Texas Cardiology Research Center, Kingwood, Texas
Ascension Texas Cardiovascular, Kyle, Texas
Cardiovoyage, Sherman, Texas
Northwest Heart Clinical Research, LLC., Tomball, Texas
Virginia Heart, Falls Church, Virginia
Riverside Regional Medical Center, Newport News, Virginia
Sentara Cardiovascular Research Institute, Norfolk, Virginia
Winchester Medical Center, Winchester, Virginia
Providence Regional Medical Center Everett, Everett, Washington
Cardiac Surgery Group, Tacoma, Washington
MultiCare Health System, Tacoma, Washington
Mayo Clinic Health System, La Crosse, Wisconsin
Marshfield Clinic, Marshfield, Wisconsin
Hospital Espanol De Bahia Blanca, Bahia Blanca, Not set
Hospital Italiano Regional Del Sur, Bahia Blanca, Not set
Sanatorio Finochietto, Buenos Aires, Not set
Sanatorio Guemes, Caba, Not set
Centro Medico Dra. Laura Maffei - Investigacion Clinica Aplicada, Ciudad Autonoma Buenos Aires, Not set
Instituto Cardiovascular de Buenos Aires, Ciudad Autonoma Buenos Aires, Not set
Fundacion Favaloro, Ciudad Autonoma Buenos Aires, Not set
Clinica Adventista Belgrano, Ciudad Autonoma Buenos Aires, Not set
Hospital Italiano de Buenos Aires, Ciudad Autonoma de Buenos Aires, Not set
Hospital Britanico de Buenos Aires, Ciudad Autonoma de Buenos Aires, Not set
Clínica Chutro, Cordoba, Not set
Hospital San Roque, Cordoba, Not set
Sanatorio Duarte Quiroz, Cordoba, Not set
Clinica Romagosa, Cordoba, Not set
Clinica Privada del Prado, Cordoba, Not set
Sanatorio Allende, Cordoba, Not set
Sanatorio de la Canada, Cordoba, Not set
Instituto Privado De Especialidades Medicas S.A. Fundacion J Robert Cade, Cordoba, Not set
Hospital Cordoba, Cordoba, Not set
Centro Medico Luquez, Cordoba, Not set
Hospital Privado Centro Medico de Cordoba, Cordoba, Not set
Clinica Coronel Suarez, Coronel Suarez, Not set
Hospital El Cruce, Florencio Varela, Not set
Hospital Italiano de La Plata, La Plata, Not set
Centro de Investigaciones Medicas Mar Del Plata, Mar del Plata, Not set
Sanatorio Modelo de Quilmes, Quilmes, Not set
Instituto Cardiovascular de Rosario, Rosario, Not set
Sanatorio Parque, Rosario, Not set
Hospital Italiano Garibaldi, Rosario, Not set
Hospital Provincial del Centenario, Rosario, Not set
Centro de Investigaciones Clinicas Salta, Salta, Not set
Centro Cardiovascular Salta, Salta, Not set
Corporacion Medica de Gral. San Martin S.A., San Martin, Not set
Investigaciones Clinicas Tucuman, San Miguel de Tucuman, Not set
Estudios Clinicos de los Arroyos, San Nicolas, Not set
Sanatorio Mayo SA, Santa Fe, Not set
Hospital José María Cullen, Santa Fe, Not set
Sanatorio Medico de Diagnostico y Tratamiento, Santa Fe, Not set
Sanatorio San Martin, Venado Tuerto, Not set
Clinica Privada Fusavim SRL, Villa Maria, Not set
Royal Adelaide Hospital, Adelaide, Not set
Flinders Medical Centre, Adelaide, Not set
Ballarat Base Hospital, Ballarat, Not set
Sunshine Coast University Hospital, Birtinya, Not set
Cairns Base Hospital, Cairns, Not set
Royal Prince Alfred Hospital, Camperdown, Not set
Concord Repatriation General Hospital, Concord, Not set
The Canberra Hospital, Garran, Not set
Royal Brisbane and Women's Hospital, Herston, Not set
Royal Hobart Hospital, Hobart, Not set
Nepean Hospital, Kingswood, Not set
Core Research Group, Milton, Not set
Fiona Stanley Hospital, Murdoch, Not set
Gold Coast University Hospital, Southport, Not set
Westmead Hospital, Sydney, Not set
Latrobe Regional Hospital, Traralgon, Not set
Wollongong Hospital, Wollongong, Not set
The Queen Elizabeth Hospital, Woodville South, Not set
KH St.Josef Braunau am Inn, Braunau am Inn, Not set
Landeskrankenhaus Feldkirch, Feldkirch, Not set
LKH-Univ. Klinikum Graz, Graz, Not set
Krankenhaus der Elisabethinen Linz, Linz, Not set
AKH - Medizinische Universitat Wien, Wien, Not set
Imeldaziekenhuis, Bonheiden, Not set
AZ Klina, Brasschaat, Not set
AZ Sint-Jan, Brugge, Not set
Universitair Ziekenhuis Brussel, Brussels, Not set
C.H.U. Brugmann, Bruxelles, Not set
CUB Hôpital Erasme, Bruxelles, Not set
Cliniques Universitaires Saint Luc, Bruxelles, Not set
Ziekenhuis Oost-Limburg, Genk, Not set
AZ Sint-Lucas, Gent, Not set
Jessa Ziekenhuis, Hasselt, Not set
CHR de la Citadelle, Liege, Not set
Az Sint-Maarten, Mechelen, Not set
Heilig Hart Ziekenhuis Lier, Mol, Not set
CHU Ambroise Pare, Mons, Not set
AZ Delta, Roeselare, Not set
AZ Turnhout, Turnhout, Not set
Hospital Vera Cruz, Belo Horizonte, Not set
IMINC Instituto Mineiro de Intervencao Cardiologica LTDA, Belo Horizonte, Not set
Cardresearch - Cardiologia Assistencial, Belo Horizonte, Not set
Instituto das Pequenas Missionárias de Maria Imaculada - Hospital Madre Teresa, Belo Horizonte, Not set
UNESP - Faculdade de Medicina da Universidade Estadual Paulista - Campus Botucatu, Botucatu, Not set
Hospital do Coracao do Brasil, Brasilia, Not set
Centro de Cardiologia Clinica e Pesquisa Doutora Juliana Souza Ltda CECAP Centro de Cardiologia Clinica, Brasilia, Not set
Sociedade Hospitalar Angelina Caron, Campina Grande Do Sul, Not set
C.E.C.-Centro Especializado em Cardiologia Ltda.- Loema Medicina e Bem Estar, Campinas, Not set
Instituto de Pesquisa Clinica de Campinas, Campinas, Not set
Sociedade Literaria e Caritativa Santo Agostinho Hospital Sao Jose, Criciúma, Not set
Irmandade Santa Casa de Misericordia de Curitiba, Curitiba, Not set
Associacao Paranaense de Cultura PUCPR, Curitiba, Not set
Hospital Cardiológico Costantini, Curitiba, Not set
Hospital Das Clinicas Da Universidade Federal De Goias, Goiania, Not set
Instituto do Coracao de Marília, Marilia, Not set
Instituto Atena de Pesquisa Clinica, Natal, Not set
Instituto Mederi de Pesquisa e Saude, Passo Fundo, Not set
Santa Casa de Misericordia de Pelotas, Pelotas, Not set
Associacao Hospitalar Moinhos de Vento, Porto Alegre, Not set
Hospital das Clinicas de Porto Alegre, Porto Alegre, Not set
IMV Pesquisa Cardiologica Sociedade Simples HMD COR l, Porto Alegre, Not set
Hospital Ernesto Dornelles, Porto Alegre, Not set
Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da PUCRS, Porto Alegre, Not set
Fundacao Universitaria de Cardiologia, Porto Alegre, Not set
Hospital Nossa Senhora da Conceicao S A, Porto Alegre, Not set
Hospital Maternidade e Pronto Socorro Santa Lucia, Poços de Caldas, Not set
PROCAPE - Universidade de Pernambuco Pronto Socorro Cardiológico de Pernambuco prof Luiz Tavares, Recife, Not set
Secretaria de Saude Hospital Agamenon Magalhaes, Recife, Not set
Hospital Das Clinicas Da Faculdade De Medicina De RPUSP HCRP, Ribeirao Preto, Not set
Hospital sao lucas, Rio de Janeiro, Not set
Hospital Santa Izabel Santa Casa de Misericordia da Bahia, Salvador, Not set
Instituto CardioPulmonar, Salvador, Not set
Fundacao Bahiana de Cardiologia, Salvador, Not set
Hospital da Bahia, Salvador, Not set
Pesquisare Saude, Santo Andre, Not set
CEMEC - Centro Multidisciplinar de Estudos Clínicos, Sao Bernardo Do Campo, Not set
Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base, Sao Jose do Rio Preto, Not set
Irmandade Da Santa Casa De Misericordia De Sao Paulo, Sao Paulo, Not set
FGM Clinica Paulista de Doencas Cardiovasculares Ltda, Sao Paulo, Not set
Real e Benemerita Associacao Portuguesa de Beneficencia, Sao Paulo, Not set
Hospital Alemao Oswaldo Cruz, Sao Paulo, Not set
Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Not set
Hospital Das Clinicas Da Faculdade De Medicina Da USP, Sao Paulo, Not set
Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, Sao Paulo, Not set
Casa de Saude Santa Marcelina - Hospital Santa Marcelina, Sao Paulo, Not set
Instituto de Cardiologia de Santa Catarina, São José, Not set
Instituto de Moléstias Cardiovasculares Tatuí, Tatuí, Not set
HC-UFTM - Hospital de Clínicas da Universidade Federal do Triângulo Mineiro, Uberaba, Not set
Clinica Cardioped Ltda, Vitoria, Not set
CEDOES, Vitória, Not set
Santa Casa de Misericórdia de Votuporanga, Votuporanga, Not set
MHAT Puls, Blagoevgrad, Not set
MHAT Heart and Brain, Burgas, Not set
Multiprofile Hospital for Active Treatment Dr. Tota Venkova, Gabrovo, Not set
Multiprofile Hospital for Active Treatment - Haskovo, Haskovo, Not set
MHAT Uni Hospital, Panagyurishte, Not set
SHATC Sveti Georgi-Pernik OOD, Pernik, Not set
Multiprofile Hospital for Active Treatment Heart and Brain, Pleven, Pleven, Not set
UMHAT 'Dr. Georgi Stranski', EAD, Pleven, Not set
UMHAT 'Sv. Georgi' EAD, Plovdiv, Not set
MHAT Sv. Karidad EAD, Plovdiv, Not set
2th MHAT - Sofia, Sofia, Not set
National Heart Hospital, Sofia, Not set
Diagnostic Consultation Centre 'Alexandrovska' EOOD, Sofia, Not set
UMHAT Prof. Dr. Aleksandar Chirkov, Sofia, Not set
University Multiprofile Hospital for Active Treatment - Tsaritsa Yoanna - ISUL, EAD, Sofia, Not set
UMHATEM N I Pirogov, Sofia, Not set
University Multiprofile Hospital for Active Treatment- UMHAT Sveta Anna AD, Sofia, Not set
UMHAT Sofia Med, Sofia, Not set
UMHAT Prof. Dr. St. Kirkovich AD, Stara Zagora, Not set
Foothills Hospital, Calgary, Alberta
University of Alberta, Edmonton, Alberta
Surrey Memorial Hospital, Surrey, British Columbia
Vancouver General Hospital, Vancouver, British Columbia
Saint Boniface General Hospital, Winnipeg, Manitoba
Dalhousie University, Halifax, Nova Scotia
Dr. Saul Vizel Cardiac Research Office, Cambridge, Ontario
Hamilton Health Sciences Corporation, Hamilton, Ontario
London Health Sciences Centre, London, Ontario
Southlake Regional Health Centre, Newmarket, Ontario
Halton Healthcare Services Corporation, Oakville, Ontario
University of Ottawa Heart Institute, Ottawa, Ontario
Kawartha Cardiology Clinical Trials, Peterborough, Ontario
Niagara Health System, St Catharines, Ontario
Toronto Sunnybrook Hospital, Toronto, Ontario
Office of Dr. Anthony Glanz, Windsor, Ontario
Clinique de Cardiologie de Levis, Levis, Quebec
Centre de Recherche du CHUM, Montreal, Quebec
Montreal General Hospital, Montreal, Quebec
CardioVasc HR, St Jean sur Richelieu, Quebec
CSSS du Sud de Lanaudiere - Hopital Pierre-Le Gardeur d/b/a CISSS de Lanaudiere, Terrebonne, Quebec
CIUSSS de la Mauricie-et-du-Centre-du-Quebec, Trois-Rivières, Quebec
Royal University Hospital, Saskatoon, Saskatchewan
Montreal Heart Institute, Quebec, Not set
Centre de Recherche Clinique de Quebec, Quebec, Not set
Institut Universitaire De Cardiologie Et De Pneumologie De Québec, Quebec, Not set
Quantum Research, Puerto Varas, Not set
Centro de Investigacion Clinica Universidad Catolica de Chile CICUC, Santiago, Not set
Centro de Estudios Cardiologicos y de Medicina Interna, Temuco, Not set
Centro de Investigacion Clinica del Sur, Temuco, Not set
Centro de Estudios Clinicos V Region Ltda, Vina del Mar, Not set
Baotou Central Hospital, Baotou, Not set
Beijing Anzhen Hospital, Capital Medical University, Beijing, Not set
Peking University First Hospital, Beijing, Not set
Beijing Shijitan Hospital, Beijing, Not set
Beijing Friendship Hospital Capital Medical University, Beijing, Not set
Peking University Third Hospital, Beijing, Not set
Chinese PLA General Hospital, Beijing, Not set
The First Hospital of Jilin University, Changchun, Not set
Changzhou No 2 Peoples Hospital, Changzhou, Not set
West China Hospital Sichuan University, Chengdu, Not set
Sichuan Provincial Peoples Hospital, Chengdu, Not set
The First Affiliated Hospital of Chongqing Medical University, Chongqing, Not set
Dongguan People s Hospital, Dongguan, Not set
The First Affiliated Hospital of Fujian Medical University, Fuzhou, Not set
Guangdong Provincial People's Hospital, Guangzhou, Not set
The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Not set
The Affiliated Hospital of Guizhou Medical University, Guiyang, Not set
GuiZhou Privicial Peoples Hospital, Guiyang, Not set
Zhejiang Provincial People's Hospital, Hangzhou, Not set
Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Not set
Sir Run Run Shaw Hospital Zhejiang University School of Medicine, Hangzhou, Not set
Anhui Province Hospital, Hefei, Not set
Huizhou Municipal Central Hospital, Huizhou, Not set
Qilu Hospital of Shandong University, Jinan, Not set
The Second Affiliated Hospital, Shandong University, Jinan, Not set
Shandong Jining No.1 People's Hospital, Jining, Not set
Lanzhou University Second Hospital, Lanzhou, Not set
Linfen Central Hospital, Linfen, Not set
The Second Affiliated Hospital of Nanchang University, Nanchang, Not set
Nanjing Drum Tower Hospital, Nanjing, Not set
Zhongda Hospital Southeast University, Nanjing, Not set
Jiangsu Province Hospital, Nanjing, Not set
The First Affiliated Hospital of Nanyang Medical College, Nanyang, Not set
Ningbo First Hospital, Ningbo, Not set
Shanghai Ninth Peoples Hospital, Shanghai, Not set
Shanghai Chest Hospital, Shanghai, Not set
Zhongshan Hospital Fudan University, Shanghai, Not set
The First Affiliated Hospital of Shantou University Medical, Shantou, Not set
Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, Shenzhen, Not set
The Second Affiliatted Hospital of Soochow University, Su Zhou, Not set
The First Affiliated Hospital of Soochow University, Suzhou, Not set
Shanxi Cardiovascular Hospital, Taiyuan, Not set
Tianjin Medical University General Hospital, Tianjin, Not set
Tianjin People's Hospital, Tianjin, Not set
The Second Hospital Of Tianjin Medical University, Tianjin, Not set
Tianjin Chest Hospital, Tianjin, Not set
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set
Wenzhou Peoples Hospital, Wenzhou, Not set
The Central Hospital of Wuhan, Wuhan, Not set
Hubei Zhongshan Hospital The Third Peoples Hospital of Hubei Province, Wuhan, Not set
Wuxi People s Hospital, Wuxi, Not set
The First Affiliated Hospital of Xian Jiaotong University, Xian, Not set
The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, Not set
The Affiliated Hospital of Xuzhou Medical College, Xuzhou, Not set
Yanbian University Hospital, Yanji, Not set
Yichang Central Pepole's Hospital, Yichang, Not set
General Hospital of Ningxia Medical Hospital, Yinchuan, Not set
Affiliated Hospital Of Guangdong Medical University, Zhanjiang, Not set
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set
Zhongshan City Peoples Hospital, Zhongshan, Not set
Affiliated Hospital of Zunyi Medical University, Zunyi, Not set
General Hospital Dubrovnik, Dubrovnik, Not set
Special Hospital for medical rehabilitation, Krapinske Toplice, Not set
Clinical Hospital Centre Rijeka, Rijeka, Not set
General Hospital Slavonski Brod, Slavonski Brod, Not set
Poliklinika Solmed, Zagreb, Not set
University Hospital Dubrava, Zagreb, Not set
Fakultni nemocnice Brno, Brno, Not set
Vojenska nemocnice Brno, Brno, Not set
Fakultni nemocnice u sv. Anny v Brne, Brno, Not set
Nemocnice Ceske Budejovice a s, Ceske Budejovice, Not set
Fakultni nemocnice Hradec Kralove, Hradec Kralove, Not set
Kardiocentrum Vysocina CZ a.s., Jihlava, Not set
Oblastní nemocnice Kolín, Kolin, Not set
Krajská nemocnice Liberec a.s., Liberec, Not set
Fakultni Nemocnice Ostrava, Ostrava-Poruba, Not set
Pardubicka krajska nemocnice a s, Pardubice, Not set
Fakultni nemocnice Plzen, Plzen, Not set
Ustredni vojenske nemocnice Praha, Prague, Not set
Fakultni nemocnice Kralovske Vinohrady, Praha 10, Not set
Kardiologie Vinohrady s r o, Praha 2, Not set
Vseobecna fakultni nemocnice v Praze, Praha 2, Not set
Institut klinicke a experimentalni mediciny, Praha 4, Not set
Nemocnice Slany, Slany, Not set
Nemocnice AGEL - Podlesi a.s., Trinec, Not set
Aarhus University Hospital, Aahus N, Not set
Amager Hospital, Copenhagen S, Not set
Bispebjerg Og Frederiksberg Hospital, Frederiksberg, Not set
Herning Regional Hospital, Herning, Not set
Holbæk Sygehus, Holbæk, Not set
Hvidovre Hospital, Hvidovre, Not set
Slagelse Sygehus, Slagelse, Not set
Odense University Hospital, Svendborg, Not set
Viborg Hospital, Viborg, Not set
CHU Angers - Hopital Hotel Dieu, Angers, Not set
CH Prive Saint-Martin, Caen Cedex, Not set
CHRU de Tours - Hopital Trousseau, Chambray Les Tours, Not set
Centre Hospitalier Sud Francilien, Corbeil Essonnes cedex, Not set
Hopital Henri Mondor, Creteil, Not set
CHU Dijon, Dijon cedex, Not set
CHU de Grenoble Hopital Albert Michallon, La Tronche, Not set
CH de Chartres - Hôpital Louis Pasteur, Le Coudray, Not set
CHRU de Lille Hopital Claude Huriez, Lille Cedex, Not set
Centre Hospitalier Saint Joseph Et Saint Luc, Lyon, Not set
Clinique Du Pont De Chaume, Montauban, Not set
CHU de Montpellier Hopital Saint Eloi, Montpellier, Not set
Centre Hospitalier Emile Muller, Mulhouse Cedex, Not set
CHU Nantes, Institut du thorax, Nantes Cedex 1, Not set
Centre Hospitalier Universitaire - de Nice - Hopital Pasteur, Nice Cedex 1, Not set
Hôpital Caremeau, Nîmes Cedex 9, Not set
Hopital Cochin, Paris cedex 14, Not set
Hopital Lariboisiere, Paris, Not set
Hopital Saint-Antoine, Paris, Not set
Hôpital Bichat - Claude Bernard, Paris, Not set
Centre Hospitalier de Pau, Pau Cedex, Not set
Hôpital du Haut Lévêque, Pessac, Not set
CHU Poitiers - Hopital la Miletrie, Poitiers, Not set
Hopital de Bicetre, Potigny, Not set
CHU Rouen Hopital Charles Nicolle, Rouen cedex, Not set
Clinique Saint-Hilaire - Centre Frédéric Joliot, Rouen, Not set
Nouvel Hopital Civil - CHU Strasbourg, Strasbourg, Not set
Hopital Rangueil, Toulouse Cedex 9, Not set
CHU de Nancy - Hopital de Brabois, Vandoeuvre les Nancy Cedex, Not set
Hopital Andre Mignot, Versailles Cedex, Not set
Klinikum am Plattenwald, Bad Friedrichshall, Not set
Universitaetsklinikum Freiburg, Bad Krozingen, Not set
Kerckhoff-Klinik Bad Nauheim, Bad Nauheim, Not set
Vivantes Klinikum Im Friedrichshain, Berlin, Not set
Charite Campus Benjamin Franklin, Berlin, Not set
Charité Campus Virchow, Berlin, Not set
Vivantes Humboldt Klinikum, Berlin, Not set
Klinikum Bielefeld, Bielefeld, Not set
Marienhausklinikum Eifel Bitburg, Bitburg, Not set
GFO Kliniken Bonn, Betriebsstaette St. Marien, Bonn-Beuel, Not set
Universitatsklinikum Bonn, Bonn, Not set
Staedisches Klinikum Brandenburg, Brandenburg an der Havel, Not set
Hospital Bremen Mitte, Bremen, Not set
Regiomed Klinikum Coburg, Coburg, Not set
St. Johannes-Hospital, Dortmund, Not set
Staedtisches Klinikum Dresden Standort Dresden Friedrichstadt, Dresden, Not set
Katholisches Krankenhaus St. Josef gGmbH - Abtlg. für Gynäkologie, Erfurt, Not set
Klinikum der Johann Wolfgang Goethe -Universitaet, Frankfurt, Not set
Universitaetsmedizin Greifswald, Greifswald, Not set
Universitaetsklinikum Hamburg Eppendorf, Hamburg, Not set
Asklepios Klinik Barmbek, Hamburg, Not set
Asklepios Klinik St. Georg, Hamburg, Not set
Klinikum Leverkusen gGmbH, Leverkusen, Not set
Herzzentrum Ludwigshafen, Ludwigshafen, Not set
Klinikum Luedenscheid, Luedenscheid, Not set
Universitätsklinikum Magdeburg, Magdeburg, Not set
Katholisches Klinikum Mainz; Innere Medizin I- Kardiologie, Mainz, Not set
Universitatsmedizin der Johannes Gutenberg Universitat Mainz, Mainz, Not set
Universitaetsklinikum Mannheim, Mannheim, Not set
Kliniken Maria Hilf GmbH, Moenchengladbach, Not set
Marienhaus Klinikum, Neuwied, Not set
Sana-Klinikum Remscheid GmbH, Remscheid, Not set
Universitaetsmedizin Rostock, Rostock, Not set
Universitaetsklinikum Tuebingen, Tübingen, Not set
Klinikum Worms gGmbH, Worms, Not set
Uni General Hospital of Alexandroupolis, Alexandroupolis, Not set
Henry Dunant Hospital, Athens, Not set
Hippokration Hospital, Athens, Not set
General Hospital of Athens Attikon, Athens, Not set
General Hospital of Attiki 'KAT', Athens, Not set
Athens Medical Center, Athens, Not set
General Hospital of Athens G Gennimatas, Athens, Not set
General Per Hospital of Athens Asklipiio Voulas, Athens, Not set
University Hospital of Heraklion, Heraklion, Not set
University General Hospital of Ioannina, Ioannina, Not set
University Hospital Of Larissa, Larissa, Not set
General University Hospital of Patras, Patra, Not set
Ahepa University General Hospital of Thessaloniki, Thessaloniki, Not set
Hippokration Hospital, Thessaloniki, Not set
Papageorgiou General Hospital, Thessaloniki, Not set
Papanikolaou General Hospital of Thessaloniki, Thessaloniki, Not set
Budai Irgalmasrendi Korhaz, Budapest, Not set
Semmelweis Egyetem, Budapest, Not set
Gottsegen György Országos Kardiológiai Intézet, Budapest, Not set
Bajcsy-Zsilinszky Kórház és Rendelőintézet, Budapest, Not set
Semmelweis Egyetem Varosmajor Sziv es Ergyogyaszati Klinika, Budapest, Not set
Debreceni Egyetem, Debrecen, Not set
Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz, Gyula, Not set
Somogy Megyei Kaposi Mor Oktato Korhaz, Kaposvar, Not set
Bacs-kiskun Megyei Korhaz, Kecskemet, Not set
Pecsi Tudomanyegyetem, Pecs, Not set
Szegedi Tudományegyetem Áok Szent-Györgyi Albert Klinikai Központ, Szeged, Not set
Tolna Megyei Balassa Janos Korhaz, Szekszárd, Not set
Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointez, Szolnok, Not set
Markusovszky Egyetemi Oktatokorhaz, Szombathely, Not set
Belvarosi Egeszseghaz Kft. (Leda-Platan Maganklinika es Sebeszeti Kozpont), Zalaegerszeg, Not set
NHL Medical College (SVP Hospital IMSR), Ahmedabad, Not set
Jawaharlal Nehru Medical College and Hospital, Aligarh, Not set
Sri Jayadeva Institute, Bangalore, Not set
KLE's Dr. Prabhakar Kore Hospital & Medical Research Centre (MRC), Belgaum, Not set
S.P.Medical College & AG of Hospitals, Bikaner, Not set
Tamil Nadu Government Multi Super Speciality Hospital, Chennai, Not set
Apollo Hospitals, Chennai, Not set
Lisie Hospital, Cochin, Not set
Batra Hospital And Medical Research Centre, Delhi, Not set
Osmania General Hospital, Hyderabad, Not set
Care Hospitals, Hyderbad, Not set
NRS Medical College, Kolkata, Not set
IPGMER and SSKM Hospital, Kolkata, Not set
Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata, Not set
Dayanand Medical College & Hospital, Tagore Nagar, Civil Lines, Ludhiana, Not set
Kasturba Medical College Hospital, Mangalore, Not set
Seth G S Medical College and KEM Hospital, Mumbai, Not set
Arneja Heart Institute, Nagpur, Not set
Crescent Hospital & Heart Center, Nagpur, Not set
Central India Cardiology Hospital and Research Institute, Nagpur, Not set
All India Institute of Medical Sciences, New Delhi, Not set
Sir Ganga Ram Hospital, New Delhi, Not set
Indira Gandhi Institute of Medical Sciences, Patna, Not set
Ruby Hall Clinic, Pune, Not set
KEM Hospital & Research Centre, Pune, Not set
Nanjappa Hospital, Shimoga, Not set
Unicare Heart Institute, Surat, Not set
Government Siddhartha Medical College, Vijayawada, Not set
King George Hospital, Vishakhapatnam, Not set
Haemek Medical Center, Afula, Not set
Samson Assuta Ashdod University Hospital, Ashdod, Not set
Barzilai Medical Center, Ashkelon, Not set
Soroka University Medical Center, Beersheba, Not set
Bnai Zion Medical Center, Haifa, Not set
Rambam Health Care Campus, Haifa, Not set
Carmel Medical Center, Haifa, Not set
Wolfson Medical Center, Holon, Not set
Shaare Zedek Medical Center, Jerusalem, Not set
Hadassah University Hospita Ein Kerem, Jerusalem, Not set
Hadassah Medical Center, Jerusalem, Not set
Meir Medical Center, Kfar Sava, Not set
Health Corporation of Galilee Medical Center, Naharya, Not set
Rabin Medical Center, Petah Tikva, Not set
Chaim Sheba Medical Center, Ramat Gan, Not set
Kaplan Medical Center, Rechovot, Not set
Assaf Harofeh Medical Center, Rishon Lezion, Not set
Ziv Medical Center, Safed, Not set
Baruch Padeh Medical Center, Tiberias, Not set
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo Alessandria, Alessandria, Not set
Cliniche Humanitas Gavazzeni, Bergamo, Not set
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII), Bergamo, Not set
Azienda USL di Bologna - Ospedale Maggiore, Bologna, Not set
Universita D Annunzio, Chieti, Not set
Azienda Ospedaliero-Universitaria di Ferrara Arcispedale Sant Anna, Ferrara, Not set
Ospedale Sant'Andrea, La Spezia, Not set
Azienda Ulss 3 Serenissima distretto di Mirano, Mestre, Not set
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Not set
Centro Cardiologico Monzino, Milano, Not set
Azienda Socio Sanitaria Territoriale Niguarda (Grande Ospedale Metropolitano Niguarda), Milano, Not set
Azienda Ospedaliera Universitaria Federico II, Napoli, Not set
Azienda Ospedaliero Universitaria di Parma, Parma, Not set
Fondazione IRCCS Policlinico San Matteo, Pavia, Not set
A. O.U. Pisana Ospedale di Cisanello, Pisa, Not set
AOU Policlinico Umberto I, Roma, Not set
Fondazione Policlinico Universitario A Gemelli IRCCS, Roma, Not set
Istituto Clinico Humanitas, Rozzano, Not set
Ospedale San Francesco, Sassari, Not set
Ospedale Bolognini, Seriate, Not set
IRCCS Multimedica di Sesto San Giovanni, Sesto San Giovanni, Not set
Azienda Ospedaliero Universitaria Ospedali Riuniti, Torrette Di Ancona, Not set
Azienda Ospedaliera Ospedale Treviglio-Caravaggio di Treviglio, Treviglio, Not set
Kasugai Municipal Hospital, Aichi, Not set
Hyogo Prefectural Amagasaki General Medical Center, Amagasaki shi, Not set
Chiba University Hospital, Chiba, Not set
Funabashi Municipal Medical Center, Chiba, Not set
Saiseikai Futsukaichi Hospital, Chikushino-shi, Not set
Fukui Prefectural Hospital, Fukui-shi, Not set
Fukuoka Wajiro Hospital, Fukuoka-shi, Not set
Kyushu University Hospital, Fukuoka-shi, Not set
National Hospital Organization Kyushu Medical Center, Fukuoka, Not set
Gifu Prefectural General Medical Center, Gifu, Not set
National Hospital Organization Takasaki General Medical Center, Gunma, Not set
Hyogo Prefectural Harima-Himeji General Medical Center, Himeji-shi, Not set
Hiratsuka Kyosai Hospital, Hiratsuka-shi, Not set
Hirosaki University Hospital, Hirosaki, Not set
Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Not set
Tokai University Hospital, Isehara, Not set
Public Central Hospital of Matto Ishikawa, Ishikawa, Not set
Teikyo University Hospital, Itabashi Ku, Not set
Juntendo University Shizuoka Hospital, Izunokuni-shi, Not set
Tesshokai Kameda Clinic, Kamogawa, Not set
Showa University Fujigaoka Hospital, Kanagawa, Not set
Asanokawa, Kanazawa Cardiovascular Hospital, Kanazawa-shi, Not set
Fukuoka Tokushukai Hospital, Kasuga-shi, Not set
Kimitsu Chuo Hospital, Kisarazu-shi, Not set
Kokura Memorial Hospital, Kitakyushu-shi, Not set
Chikamori Hospital, Kochi, Not set
National Hospital Organization Fukuoka Higashi Medical Center, Koga, Not set
Kumamoto University Hospital, Kumamoto-City, Not set
Saiseikai Kumamoto Hospital, Kumamoto-shi, Not set
Kurashiki Central Hospital, Kurashiki, Not set
National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Kure-shi, Not set
Kyoto University Hospital, Kyoto-shi, Not set
National Hospital Organization Kyoto Medical Center, Kyoto, Not set
Tokushukai Chiba-Nishi General Hospital, Matsudo-shi, Not set
Jisenkai Aizawa Hospital, Matsumoto-shi, Not set
Toho University Medical Center, Ohashi Hospital, Meguro-ku, Not set
Tokyo Saiseikai Central Hospital, Minato-ku, Not set
Miyazaki Medical Association Hospital, Miyazaki-shi, Not set
NHO Nagoya Medical Center, Nagoya-shi, Not set
Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya-shi, Not set
Hyogo Medical University Hospital, Nishinomiya shi, Not set
Okayama Rosai Hospital, Okayama shi, Not set
National Hospital Organization Osaka National Hospital, Osaka-shi, Not set
Osaka City General Hospital, Osaka, Not set
Osaka Police Hospital, Osaka, Not set
Kitasato University Hospital, Sagamihara, Not set
Saga University Hospital, Saga, Not set
Iwatsuki Minami Hospital, Saitama-shi, Not set
National Hospital Organization Saitama National Hospital, Saitama, Not set
Tohoku University Hospital, Sendai, Not set
Showa University Hospital, Shinagawa, Not set
Tokyo Women's Medical University Hospital, Shinjuku-ku, Not set
Iwate Medical University Hospital, Shiwa-gun, Not set
National Cerebral and Cardiovascular Center, Suita-Shi, Not set
Kagawa Prefectural Central Hospital, Takamatsu, Not set
Tokushima University Hospital, Tokushima, Not set
Mitsui Memorial Hospital, Tokyo, Not set
St. Luke's International Hospital, Tokyo, Not set
Nippon Medical School Hospital, Tokyo, Not set
National Hospital Organization Tokyo Medical Center, Tokyo, Not set
Nihon University Itabashi Hospital, Tokyo, Not set
Ome Medical Center, Tokyo, Not set
Toyama Prefectural Central Hospital, Toyama-shi, Not set
Tsuchiura Kyodo General Hospital, Tsuchiura-City, Not set
Tsukuba Medical Center Hospital, Tsukuba shi, Not set
Mie University Hospital, Tsu, Not set
Yamaguchi University Hospital, Ube, Not set
Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu-shi, Not set
National Hospital Organization Ureshino Medical Center, Ureshino-shi, Not set
Wakayama Medical University Hospital, Wakayama, Not set
Yokohama City University Medical Center, Yokohama, Not set
Bucheon St. Mary's Hospital, Bucheon-si, Not set
Inje University Busan Paik Hospital, Busan, Not set
Pusan National University Hospital, Busan, Not set
Dong-A University Hospital, Busan, Not set
Chungbuk National University Hospital, Cheongju-si, Not set
Kangwon National University Hospital, Chuncheon, Not set
Keimyung University Dongsan Hospital, Daegu, Not set
Konyang University Hospital, Daejeon, Not set
Chungnam National University Hospital, Daejeon, Not set
Ewha Woman's University Seoul Hospital, Gangseo-gu, Not set
Myongji Hospital, Goyang-si, Not set
Chonnam National University Hospital, Gwangju, Not set
Seoul National University Bundang Hospital, Gyeonggi Do, Not set
Gachon University Gil Medical Center, Incheon, Not set
The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, Not set
Chungnam National University Sejong Hospital, Sejong-si, Not set
Korea University Anam Hospital, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
VHS Medical Center, Seoul, Not set
Asan Medical Center, Seoul, Not set
Gangnam Severance Hospital, Yonsei University Health System, Seoul, Not set
Seoul St.Mary s Hospital, Seoul, Not set
Severance Hospital Yonsei University Health System, Seoul, Not set
Kyung Hee University Hospital, Seoul, Not set
Kyung Hee University Hospital at Gangdong, Seoul, Not set
Hanyang University Hospital, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
WonJu Severance Christian Hospital, Wonju, Not set
Pusan National University Yangsan Hospital, Yangsan Si, Not set
Daugavpils Regional Hospital, Daugavpils, Not set
Riga East Clinical University Hospital, Riga, Not set
Pauls Stradins Clinical University Hospital, Riga, Not set
Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Not set
Klaipeda Seamen's Hospital, Public Institution, Klaipeda, Not set
Vilnius University Hospital Santariskiu Clinic, Public Institution, Vilnius, Not set
Hospital Raja Perempuan Zainab Ii, Kota Bahru, Not set
Hospital University Sains Malaysia, Kota Bharu, Not set
Hospital Queen Elizabeth, Kota Kinabalu, Not set
Institut Jantung Negara, Kuala Lumpur, Not set
Pusat Perubatan Universiti Kebangsaan Malaysia, Kuala Lumpur, Not set
University Malaya Medical Centre, Kuala Lumpur, Not set
Sarawak General Hospital, Kuching, Not set
Hospital Miri, Miri, Not set
Hospital Pulau Pinang, Pulau Pinang, Not set
Hospital Seberang Jaya, Seberang Jaya, Not set
Universiti Teknologi Mara, Selayang, Not set
Hospital Cardiologica Aguascalientes, Aguascalientes, Not set
Centro para el Desarrollo de la Medicina y de Asistencia Médica Especializada S.C., Culiacan, Not set
Centro de Estudios de de alta Especialidad de Sinaloa, Mazatlan, Not set
Instituto Nacional de Cardiologia Dr. Ignacio Chavez, Mexico, Not set
Private Practice Dr Amaya, Monterrey, Not set
Centro de Estudios Clinicos de Queretaro S.C, Queretaro, Not set
Centro de Atencion e Investigacion Cardiovascular del Potosi S C, San Luis Potosí, Not set
Centro de Investigacion Cardiovascular y Metabolica, Tijuana, Not set
Centro de Investigacion Dr. Alberto Esteban Bazzoni Ruiz, Torreon, Not set
Dr Enrique Lopez Rosas, Xalapa, Not set
Noordwest Ziekenhuisgroep, Alkmaar, Not set
Ziekenhuisgroep Twente, Almelo, Not set
Meander Medisch Centrum, Amersfoort, Not set
Onze Lieve Vrouwe Gasthuis, Amsterdam, Not set
Deventer Ziekenhuis, Deventer, Not set
Ziekenhuis Gelderse Vallei, Ede, Not set
Catharina Ziekenhuis, Eindhoven, Not set
Treant Zorggroep, Emmen, Not set
Medisch Spectrum Twente, Enschede, Not set
Admiraal De Ruyter Ziekenhuis - Goes, Goes, Not set
Groene Hart Ziekenhuis, Gouda, Not set
Ziekenhuis St Jansdal, Harderwijk, Not set
Zuyderland Medical Center, Heerlen, Not set
Elkerliek Ziekenhuis, Helmond, Not set
Alrijne Ziekenhuis Leiden ; Cardiology, Leiderdorp, Not set
Maastricht UMC, Maastricht, Not set
St. Antonius Ziekenhuis Nieuwegein, Nieuwegein, Not set
Radboudumc, Nijmegen, Not set
Bravis, Roosendaal, Not set
Sint Franciscus Gasthuis, Rotterdam, Not set
Jeroen Bosch Ziekenhuis, s-Hertogenbosch, Not set
D & A Research, Sneek, Not set
Ziekenhuis Rivierenland, Tiel, Not set
Diakonessenhuis, Utrecht, Not set
Maxima Medisch Centrum, Veldhoven, Not set
VieCuri Medisch Centrum, Venlo, Not set
Gelre Ziekenhuizen Zutphen, Zutphen, Not set
North Shore Hospital, Auckland, Not set
Auckland City Hospital, Auckland, Not set
University of Otago, Christchurch, Not set
Dunedin Public Hospital, Dunedin, Not set
Hawkes Bay Hospital, Hastings, Not set
Taranaki Base Hospital, New Plymouth, Not set
Middlemore Hospital, Otahuhu, Not set
Rotorua Hospital, Rotorua, Not set
Tauranga Hospital, Tauranga, Not set
Whangarei Hospital, Whangarei, Not set
University Clinic of Cardiology, Skopje, Not set
Clinical Hospital Tetovo, Tetovo, Not set
The Heart Specialists Clinic and Diagnostic Center, Angeles, Not set
Silang Specialists Medical Center, Cavite, Not set
Cebu Doctors University Hospital, Cebu, Not set
Central Lab Diabetes Wellness, Heart and Kidneys, Inc, Davao City, Not set
Southern Philippines Medical Center, Davao City, Not set
Davao Doctors Hospital, Davao, Not set
St.Paul's Hospital-Iloilo, Iloilo, Not set
Mary Mediatrix Medical Center, Lipa City, Not set
Health Cube Medical Clinics, Mandaluyong, Not set
Manila Doctors Hospital, Manila, Not set
Medical Center Manila, Manila, Not set
Philippine General Hospital, Manila, Not set
Chinese General Hospital & Medical Center, Manila, Not set
Amang Rodriguez Memorial Medical Center, Marikina City, Not set
The Medical City, Pasig City, Not set
St. Luke's Medical Center, Quezon, Not set
Cardinal Santos Medical Center, San Juan, Not set
The Medical City South Luzon, Sta Rosa, Not set
Uniwersytecki Szpital Kliniczny w Bialymstoku, Bialystok, Not set
NZOZ Centrum Medyczne KERmed, Bydgoszcz, Not set
Samodzielny Publiczny Zaklad Opieki Zdrowotnej, Bytom, Not set
Wojewodzki Szpital Zespolony w Elblagu, Elblag, Not set
Clinical Medical Research Sp. z o.o., Katowice, Not set
Specjalistyczna Poradnia Kardiologiczna i Nadcisnienia Tetniczego, Kielce, Not set
Ewa Mirek-Bryniarska Specjalistyczna Praktyka Lekarska, Krakow, Not set
Krakowskie Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii, Krakow, Not set
Krakowski Szpital Specjalistyczny im Jana Pawla II, Krakow, Not set
SPZOZ Centralny Szpital Kliniczny UM w Lodzi, Lodz, Not set
1 Wojskowy Szpital Kliniczny Z Poliklinika SPZOZ W Lublinie, Lublin, Not set
Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin, Not set
NZOZ Osrodek Kardiologii Inwazyjnej -Ikardia, Naleczow, Not set
Wojewodzki Szpital Specjalistyczny w Olsztynie, Olsztyn, Not set
FutureMeds Olsztyn, Olsztyn, Not set
Medicome Sp. Z O.O., Oswiecim, Not set
Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Poznan, Not set
Wojewodzki Szpital im Sw Ojca Pio w Przemyslu, Przemysl, Not set
Samodzielny Publiczny Szpital Wojewodzki im. Papieza Jana Pawla II, Siedlce, Not set
ETG Skierniewice, Skierniewice, Not set
NZOZ PRO CORDIS Sopockie Centrum Badan Kardiologicznych, Sopot, Not set
Wojewodzki Szpital Zespolony im L Rydygiera w Toruniu, Torun, Not set
Specjalistyczny Szpital im dra Alfreda Sokolowskiego w Walbrzychu, Walbrzych, Not set
Narodowy Instytut Kardiologii Stefana kardynala Wyszynskiego Panstwowy Instytut Badawczy, Warszawa, Not set
Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu, Wroclaw, Not set
4 Wojskowy Szpital Kliniczny Z Poliklinika SP ZOZ, Wroclaw, Not set
Wojewodzki Szpital Specjalistyczny we Wroclawiu, Wroclaw, Not set
Centro Hospitalar do Baixo Vouga E P E Unidade de Aveiro, Aveiro, Not set
Hospital de Braga, Braga, Not set
Uls Coimbra - Hosp. Univ. Coimbra, Coimbra, Not set
Centro Hospitalar Cova da Beira, EPE - Hospital Pêro da Covilhã, Covilha, Not set
Uls Alto Ave - Hosp. Sra. Da Oliveira Guimaraes, Guimaraes, Not set
Centro Hospitalar de Leiria, Leiria, Not set
Centro Hospitalar de Lisboa Norte Hospital Santa Maria, Lisboa, Not set
Centro Hospitalar de Lisboa Central, Lisbon, Not set
Centro Hospitalar de Entre o Douro e Vouga, E.P.E, Santa Maria da Feira, Not set
Centro Hospitalar de Vila Nova de Gaia Espinho E P E, Vila Nova de Gaia, Not set
Centro Hospitalar de Trás os Montes e Alto Douro- Vila Real, Vila Real, Not set
Spitalul Judetean de Urgenta Dr. Constantin Opris, Baia-Mare, Not set
Spitalul Clinic Judetean de Urgenta Brasov, Brasov, Not set
Institutul de urgenta pentru Boli Cardiovasculare Prof. Dr. C.C. Iliescu, Bucharest, Not set
Spitalul Universitar de Urgenta Militar Central 'Dr. Carol Davila', Bucuresti, Not set
Spitalul Universitar de Urgenta Elias, Clinica de Cardiologie, Bucuresti, Not set
Spitalul Clinic de Urgenta Bucuresti, Bucuresti, Not set
Spitalul Angiocare SRL, Cluj-Napoca, Not set
Spitalul Clinic Judetean de Urgenta Cluj Napoca, Cluj-Napoca, Not set
Spitalul Clinic Judetean de Urgenta Sf. Apostol Andrei, Constanta, Not set
Spitalul Clinic Judetean de Urgenta Craiova, Craiova, Not set
Institutul de Boli Cardiovasculare Iasi, Iasi, Not set
Spitalul Clinic Judetean de Urgenta Oradea, Oradea, Not set
SAL MED Pitesti, Pitesti, Not set
Spitalul Clinic Judetean de Urgenta Targu Mures, Targu Mures, Not set
Spitalul Clinic Judetean de Urgenta Targu Mures, Tg. Mures, Not set
Clinica Medicaliss, Timisoara, Not set
Spitalul Clinic Municipal de Urgenta Timisoara, Timisoara, Not set
Institutul de Boli Cardiovasculare Timisoara, Timisoara, Not set
Clinical Center Dr Dragisa Misovic Dedinje, Belgrade, Not set
Institute for Cardiovascular diseases Dedinje, Belgrade, Not set
University Clinical Center of Serbia, Belgrade, Not set
Clinical Hospital Center Zemun, Belgrade, Not set
University Clinical Hospital Center Dr Dragisa Misovic- Dedi, Belgrade, Not set
University Clinical Center Kragujevac, Kragujevac, Not set
Institute for Treatment and Rehabilitation Niska Banja, Niska Banja, Not set
Clinical Center Nis, Nis, Not set
General Hospital Pancevo, Pancevo, Not set
General Hospital Smederevo, Smederevo, Not set
Institute for Pulmonary Disease of Vojvodina, Sremska Kamenica, Not set
Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Not set
General Hospital Sremska Mitrovica, Sremska Mitrovica, Not set
General Hospital Uzice, Uzice, Not set
Health Center Zajecar, Zajecar, Not set
National University Hospital, Singapore, Not set
National Heart Centre (NHC) Singapore, Singapore, Not set
Changi General Hospital, Singapore, Not set
Ng Teng Fong General Hospital, Singapore, Not set
Khootech Puat Hospital, Singapore, Not set
Stredoslovensky ustav srdcovych a cievnych chorob a.s, Banska Bystrica, Not set
Alian s.r.o., Bardejov, Not set
Premedix Clinic, Bratislava, Not set
Nemocnica s poliklinikou Brezno, Brezno, Not set
Interno Kardio s r o, Kosice, Not set
Kardiologicka ambulancia CARDIO D&R s.r.o., Kosice, Not set
Východoslovenský Ústav Srdcových A Cievnych Chorôb, A.S., Košice, Not set
Kardio 1 S.R.O., Lucenec, Not set
Univerzitná nemocnica Martin, Martin, Not set
Kardiologicka ambulancia MEDI M&M s.r.o., Moldava nad Bodvou, Not set
Kardiocentrum Nitra s.r.o., Nitra, Not set
Cardioinvest s.r.o., Nove Zamky, Not set
Interna SK s.r.o., Svidnik, Not set
MEDIVASA s.r.o., Zilina, Not set
Nemocnica AGEL Zvolen a s, Zvolen, Not set
Panorama MediClinic, Cape Town, Not set
Tread Research, Cape Town, Not set
Tiervlei Trial Centre, Cape Town, Not set
Groote Schur Hospital, Cape Town, Not set
Johese Clinical Research, Centurion, Not set
Durban Medical Centre, Durban, Not set
Garda, RA, Johannesburg, Not set
Eden Heart, Mossel Bay, Not set
Dr J.M. Engelbrecht Trial Site, Somerset West, Not set
Helderberg Research Institute, Somerset West, Not set
Clinical Projects Research SA (PTY) LTD, Worcester, Not set
Hosp. Gral. Univ. de Alicante, Alicante, Not set
Hosp. Del Mar, Barcelona, Not set
Hosp. de La Santa Creu I Sant Pau, Barcelona, Not set
Hosp Univ Vall D Hebron, Barcelona, Not set
Hosp Clinic de Barcelona, Barcelona, Not set
Hosp. Univ. Virgen de La Arrixaca, El Palmar, Not set
Hosp. de Cabuenes, Gijon, Not set
Hosp. Univ. Arnau de Vilanova de Lleida, Lleida, Not set
Hosp. Virgen de La Luz, Madrid, Not set
Hosp. Univ. de La Princesa, Madrid, Not set
Hosp. Univ. Ramon Y Cajal, Madrid, Not set
Hosp. Clinico San Carlos, Madrid, Not set
Hosp. Univ. 12 de Octubre, Madrid, Not set
Hosp. Univ. La Paz, Madrid, Not set
Hosp. Univ. Hm Monteprincipe, Madrid, Not set
Hosp Virgen de La Victoria, Malaga, Not set
Hosp. de Manises, Manises, Not set
Complejo Hosp. de Navarra, Pamplona, Not set
Hosp. Clinico Univ. de Santiago, Santiago de Compostela, Not set
Hosp. Univ. Joan Xxiii, Tarragona, Not set
Hosp. Clinico Univ. de Valencia, Valencia, Not set
Hosp. Gral. Univ. Valencia, Valencia, Not set
Hosp. Alvaro Cunqueiro, Vigo, Not set
Hosp. Univ. Miguel Servet, Zaragoza, Not set
Universitatsspital Basel, Basel, Not set
Universitätspital Bern, Universitätsklinik für Frauenheilkunde, Bern, Not set
Hopitaux Universitaires de Geneve - HUG, Geneve 14, Not set
Istituto Cardiocentro Ticino, Lugano, Not set
UniversitaetsSpital Zuerich, Zuerich, Not set
Changhua Christian Hospital, Changhua, Not set
Kaohsiung Medical University Chung Ho Memorial Hospital, Kaohsiung, Not set
E-DA Hospital, Kaohsiung, Not set
Far Eastern Memorial Hospital, New Taipei, Not set
Mackay Memorial Hospital, New Taipei, Not set
China Medical University Hospital, Taichung, Not set
Chi Mei Medical Center Yong Kang, Tainan, Not set
Taipei Medical University, Taipei City, Not set
National Taiwan University Hospital, Taipei, Not set
Cathay General Hospital, Taipei, Not set
Taipei Veterans General Hospital, Taipei, Not set
Cheng Hsin General Hospital, Taipei, Not set
Tri-Service General Hospital, Taipei, Not set
Taipei Municipal Wanfang Hospital, Taipei, Not set
Chang Gung Memorial Hospital- Linkou, Taoyuan County, Not set
National Yang-Ming University Hospital, Yilan County, Not set
Siriraj Hospital, Bangkoknoi, Not set
Ramathibodi Hospital, Bangkok, Not set
Maharaj Nakorn Chiang Mai Hospital, Chiangmai, Not set
Srinagarind Hospital, Nai Mueang Subdistrict Mueang, Not set
King Chulalongkorn Memorial Hospital, Pathum Wan, Not set
Afyon Kocatepe University Medical Faculty, Afyon, Not set
Ankara Etlik Speciality Hospital, Ankara, Not set
Ankara University Medical Faculty, Ankara, Not set
Ankara Numune Research and Training Hospital, Ankara, Not set
Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Not set
Osmangazi University Medical Faculty, Eskisehir, Not set
Bezmi Alem Vakif University Medical Faculty Hospital, Istanbul, Not set
Marmara University Pendik Training Hospital, Istanbul, Not set
Dokuz Eylul University Medical Faculty, Izmir, Not set
Karabuk University Medical Faculty, Karabuk, Not set
Erciyes University Medical Faculty, Kayseri, Not set
Kutahya Health Science University Evliya Celebi Research and Training Hospital, Kutahya, Not set
Mersin University Medical Faculty, Mersin, Not set
Ondokuz Mayis University, Samsun, Not set
Basingstoke And North Hampshire Hospital, Basingstoke, Not set
Royal United Hospital, Bath, Not set
Queen Elizabeth Hospital, Birmingham, Not set
Birmingham Heartlands Hospital, Birmingham, Not set
Blackpool Victoria Hospital, Blackpool, Not set
Royal Bournemouth Hospital, Bournemouth, Not set
University Hospital Bristol and Weston NHS trust, Bristol, Not set
Dorset County Hospital, Dorchester, Not set
Russels Hall Hospital, Dudley, Not set
Hairmyres Hospital, East Kilbride, Not set
Royal Infirmary of Edinburgh, Edinburgh, Not set
Royal Devon and Exeter Hospital(Wonford), Exeter, Not set
Royal Free Hospital, Hampstead, Not set
Harefield Hospital, Harefield, Not set
West Middlesex University Hospital, Isleworth, Not set
Kingston Hospital, Kingston upon Thames, Not set
Leeds General Infirmary, Leeds, Not set
Lincoln County Hospital, Lincoln, Not set
Altnagelvin Hospital, Londonderry, Not set
Barts Hospital, London, Not set
Hammersmith Hospital, London, Not set
North Manchester General Hospital, Manchester, Not set
James Cook University Hospital, Middlesbrough, Not set
Freeman Hospital, Newcastle Upon Tyne, Not set
Peterborough City Hospital, Peterborough, Not set
Derriford Hospital, Plymouth, Not set
Queen Alexandra Hospital, Portsmouth, Not set
East Surrey Hospital, Redhill, Not set
Lister Hospital, Stevenage, Not set
Morriston Hospital, Swansea, Not set
Musgrove Park Hospital, Taunton, Not set
Torbay Hospital-Devon, Torquay, Not set
Sandwell and West Birmingham Hospitals NHS Trust-Sandwell Gene, West Bromwich, Not set
Royal Albert Edward Infirmary, Wigan, Not set
Yeovil District Hospital, Yeovil, Not set
Bach Mai Hospital, Hanoi, Not set
Tam Anh General Hospital, Hanoi, Not set
103 Military Hospital, Hanoi, Not set
Hanoi Heart Hospital, Hanoi, Not set
Hanoi Medical University Hospital, Hanoi, Not set
People's Hospital 115, Ho Chi Minh, Not set
Tam Anh Hospital, Ho Chi Minh, Not set
Thong Nhat HOSPITAL, Ho Chi Minh, Not set
Tam Duc Heart Hospital, Ho Chi Minh, Not set
Conditions: Acute Coronary Syndrome
A Study to Evaluate the Effect of Ceralasertib on Drug X, Drug Y and Drug Z
Recruiting
The study aims to assess the effect of ceralasertib on the pharmacokinetics (PK) of Drug X, Drug Y and Drug Z in participants with advanced solid tumours.
The study aims to assess the effect of ceralasertib on the pharmacokinetics (PK) of Drug X, Drug Y and Drug Z in participants with advanced solid tumours. Read Less
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/14/2025
Locations: Research Site, Barcelona, Not set +3 locations
Research Site, Barcelona, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Manchester, Not set
Conditions: Advanced Solid Tumours
A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment.
Recruiting
WinGlio is a phase I study investigating neoadjuvant (before surgery) ipilimumab ( a type of immunotherapy drug) in patients with newly diagnosed glioblastoma (a form of brain cancer). Participants will receive up to 2 cycles of ipilimumab prior to the standard of care treatments for this patient group which can include debulking surgery and chemoradiation. The aim of giving the ipilimumab to the participants is to see if it is safe to treat patients with this condition with ipilimumab and also... Read More
WinGlio is a phase I study investigating neoadjuvant (before surgery) ipilimumab ( a type of immunotherapy drug) in patients with newly diagnosed glioblastoma (a form of brain cancer). Participants will receive up to 2 cycles of ipilimumab prior to the standard of care treatments for this patient group which can include debulking surgery and chemoradiation. The aim of giving the ipilimumab to the participants is to see if it is safe to treat patients with this condition with ipilimumab and also to see if the drug helps to reduce or control the patient's disease. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: University College London Hospital, London, Greater London
University College London Hospital, London, Greater London
Conditions: Glioblastoma, Gliosarcoma, Adult, Glioblastoma - Category
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