tDCS and Emotional Eating
NCT06488287
Recruiting
This research investigates the feasibility of undertaking a large, randomised control trial of transcranial direct current stimulation (tDCS) as a treatment modality for managing food cravings and emotional eating. This study explores how tDCS, a non-invasive brain stimulation technique, can influence brain activity and potentially impact appetite regulation, self-control, reward processing, and other factors related to weight management. All participants will receive 6 sessions of stimulation... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/27/2024
Locations: University of Nottingham, Derby, Royal Derby Hospital Centre Uttoxeter Road
Conditions: Eating Disorders
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Gut Hormone LEAP2 in Metabolism and Eating Behaviour: Fixed Meal Testing
NCT06013592
Recruiting
The goal of this interventional study is to measure the blood levels of the gut hormones LEAP2 and acyl ghrelin (AG), appetite and food intake after consuming liquid meals of different caloric sizes, in healthy adults with and without obesity. AG is a stomach-derived homone that increases appetite, and LEAP2 a liver-gut derived hormone that decreases appetite, which interferes the action of AG ant its receptor in the brain called the growth hormone secretagogue receptor (GHSR). Blood levels of... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
06/24/2024
Locations: PsychoNeuroEndocrinology Research Group, Division of Psychiatry, Dept. of Brain Sciences, Imperial College London, London, Not set
Conditions: Eating Behavior, Obesity, Appetitive Behavior
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Postoperative Dietary Intake of Hip Fracture Patients
NCT06451679
Recruiting
The goal of this observational study is to observe the postoperative dietary intake in older adult hip fracture patients from their day of surgery (day zero) until day three inclusive. The aims of this study are: Primary aim: To observe if the postoperative dietary energy intake (kJ/kcal) of older adult hip fracture patients meets Resting Energy Expenditure (REE) needs. Secondary aims: To explore if there is a correlation between postoperative dietary intake and length of hospital stay. To... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
06/24/2024
Locations: Teesside University, Middlesbrough, Not set
Conditions: Hip Fractures, Malnutrition, Comorbidities and Coexisting Conditions, Postoperative Complications
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The Influence of Chlorella Supplementation on Running Performance
NCT06479993
Recruiting
Algae, such as chlorella, are gaining popularity as a nutritious additive to whole food or as a supplement. They contain a variety of beneficial nutrients like vitamins, minerals, healthy fats, and amino acids, which can have positive effects on our health and possibly athletic performance. Chlorella, specifically, is a type of single-celled green algae that you can easily find in health stores worldwide. While there's some evidence suggesting that chlorella supplementation might improve submaxi... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
06/24/2024
Locations: University Colllege London (ISEH), London, Not set
Conditions: Athletes, Healthy
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Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma
NCT05948475
Recruiting
This study is a Phase III, Randomized, Controlled, Global Multicenter Study to Evaluate the Efficacy and Safety of Oral Tinengotinib versus Physician's Choice in Subjects with Fibroblast Growth Factor Receptor (FGFR)-altered, Chemotherapy- and FGFR Inhibitor-Refractory/Relapsed Cholangiocarcinoma
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/21/2024
Locations: UCLA Medical Center, Santa Monica, California +86 locations
Conditions: Cholangiocarcinoma
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Exercise Engagement in People Over 60 at Risk of Falls
NCT06100445
Recruiting
It is a qualitative study, using semi structured interviews to explore patient's experiences of falls and their perceptions on facilitators and barriers to exercise. Aim: To explore reasons for and against engaging with exercises at home in participants over the age of 60 at risk of falls. To explore: 1. Patients' preferences to exercise format and type eg/ leaflet, online, access, such as the Chartered Society of Physiotherapy (CSP) chair exercises leaflet or individual personalized rehabili... Read More
Gender:
ALL
Ages:
Between 60 years and 95 years
Trial Updated:
06/20/2024
Locations: East Lancashire Hospitals NHS Trust, Blackburn, Lancashire
Conditions: Musculoskeletal Injury, Frailty, Physical Inactivity, Health Behavior
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Mother and Baby Yoga Study - Early Postnatal Yoga and Mental Health
NCT06056609
Recruiting
Investigating the influence of an early postnatal mother and baby yoga programme on maternal mental health and relationship with baby: a randomised feasibility study. It is thought postnatal mother and baby yoga decreases levels of depression and anxiety and increases subjective experience of maternal-infant bonding. This project will provide the necessary data to determine whether a regular programme would be beneficial to mothers. The research study is an eight-week online programme incorpor... Read More
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
06/18/2024
Locations: York & Scarborough Teaching Hospitals NHS Foundation Trust, York, N. Yorks
Conditions: Mental Health Issue, Depression, Postpartum, Anxiety
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Investigating Musculoskeletal Health and Wellbeing
NCT03696134
Recruiting
Background The progression and associations of central and peripheral musculoskeletal pain, frailty, disability and fracture risks are not well known. This study aims to characterise the development and progression of different frailty, pain and disability phenotypes and their individual associations. Methods A prospective cohort of 10000 people aged \> 18 will be recruited from general practice surgeries, secondary care and the general public. Data collection waves will be at baseline,and then... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: University of Nottingham, Nottingham, Not set
Conditions: Musculoskeletal Pain, Frailty, Disability
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Bariatric Surgery and Exercise Interventions: Effects on Muscle
NCT05569785
Recruiting
The purpose of this project is to assess the effects of bariatric surgery on muscle structure and function as well as investigating the feasibility of undertaking an exercise intervention post-surgery.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/18/2024
Locations: COMAP, Derby, Not set
Conditions: Bariatric Surgery Candidate, Obesity
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PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome
NCT06447961
Recruiting
Why? PSYLIVED is a qualitative study that aims to understand the psychological experience of individuals living with inherited colorectal cancer. It addresses the question of how individuals cope emotionally and adapt to the unique challenges they face. This research sheds light on the emotional journey of those with inherited colorectal cancer, potentially leading to improved support services, interventions, and care practices tailored to their needs. The study seeks to enhance the well-being o... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
06/18/2024
Locations: The St Mark's Centre for Familial Intestinal Cancer, London, Not set
Conditions: Lynch Syndrome, Polyposis Syndrome, Hereditary Mixed, 1, Polyposis Syndrome, Hereditary Mixed, 2
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The Role of SGLT2i in Management of Moderate AS
NCT06469645
Recruiting
Background: The aortic valve is like a door in the heart that lets blood flow out to the body. Over time, this valve can get worn out and become too narrow, leading to a condition called aortic stenosis. When this happens, the heart has to work extra hard to push blood through the narrow valve to supply the body with what it needs. This extra effort can cause the heart muscle to become abnormally thick or to have fibrosis. For people with aortic stenosis, this can lead to more problems like fee... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: Norfolk and Norwich University Hospital, Norwich, Norfolk
Conditions: Moderate Aortic Valve Stenosis
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Self-compassion and Quality of Life After Dementia Diagnosis
NCT06465173
Recruiting
This study aims to investigate whether self-compassion is associated with older adult's quality of life after a diagnosis of dementia, and whether perceived threat posed by dementia mediates this relationship. Self-compassion has been found to be positive in supporting individuals in times of difficulty, in adjustment processes and older adults' wellbeing. While different factors have begun to be identified which are associated with individuals' psychological wellbeing and adjustment following a... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
06/17/2024
Locations: Oxford Health NHS Foundation Trust, Oxford, Oxfordshire
Conditions: Dementia
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