All Clinical Trials in United Kingdom

A listing of 3097 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

NCT06742723

Recruiting

International, Multicenter, Double-Blind, Placebo-Controlled and Event-driven study to assess efficacy, safety and Tolerability of Baxdrostat in combination with Dapagliflozin on renal outcomes and cardiovascular mortality in participants with chronic kidney disease and high blood pressure

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Research Site, Fairhope, Alabama +710 locations

Research Site, Fairhope, Alabama

Research Site, Surprise, Arizona

Research Site, Tucson, Arizona

Research Site, Beverly Hills, California

Research Site, Canoga Park, California

Research Site, Fremont, California

Research Site, Fullerton, California

Research Site, Inglewood, California

Research Site, Los Alamitos, California

Research Site, Los Angeles, California

Research Site, San Diego, California

Research Site, San Francisco, California

Research Site, Stanford, California

Research Site, Tarzana, California

Research Site, Arvada, Colorado

Research Site, Denver, Colorado

Research Site, New Britain, Connecticut

Research Site, Washington, District of Columbia

Research Site, Boca Raton, Florida

Research Site, Boynton Beach, Florida

Research Site, Edgewater, Florida

Research Site, Fort Lauderdale, Florida

Research Site, Hollywood, Florida

Research Site, Jacksonville Beach, Florida

Research Site, Lake City, Florida

Research Site, Melbourne, Florida

Research Site, Miami Lakes, Florida

Research Site, Ocoee, Florida

Research Site, Port Charlotte, Florida

Research Site, Port Orange, Florida

Research Site, Riverview, Florida

Research Site, Winter Haven, Florida

Research Site, Atlanta, Georgia

Research Site, Augusta, Georgia

Research Site, Austell, Georgia

Research Site, Brunswick, Georgia

Research Site, Conyers, Georgia

Research Site, Riverdale, Georgia

Research Site, Honolulu, Hawaii

Research Site, Champaign, Illinois

Research Site, Maywood, Illinois

Research Site, Rockford, Illinois

Research Site, Evansville, Indiana

Research Site, Indianapolis, Indiana

Research Site, Iowa City, Iowa

Research Site, West Des Moines, Iowa

Research Site, Hutchinson, Kansas

Research Site, Kansas City, Kansas

Research Site, Wichita, Kansas

Research Site, Kenner, Louisiana

Research Site, Metairie, Louisiana

Research Site, West Monroe, Louisiana

Research Site, Bethesda, Maryland

Research Site, Boston, Massachusetts

Research Site, New Bedford, Massachusetts

Research Site, Ann Arbor, Michigan

Research Site, Detroit, Michigan

Research Site, Garden City, Michigan

Research Site, Saint Joseph, Michigan

Research Site, Kansas City, Missouri

Research Site, Saint Louis, Missouri

Research Site, Norfolk, Nebraska

Research Site, Las Vegas, Nevada

Research Site, Eatontown, New Jersey

Research Site, Albany, New York

Research Site, New York, New York

Research Site, Greenville, North Carolina

Research Site, Hickory, North Carolina

Research Site, Jacksonville, North Carolina

Research Site, Kinston, North Carolina

Research Site, Morehead City, North Carolina

Research Site, New Bern, North Carolina

Research Site, Raleigh, North Carolina

Research Site, Rocky Mount, North Carolina

Research Site, Sanford, North Carolina

Research Site, Statesville, North Carolina

Research Site, Wilmington, North Carolina

Research Site, Winston-Salem, North Carolina

Research Site, Canton, Ohio

Research Site, Cincinnati, Ohio

Research Site, Columbus, Ohio

Research Site, Chester, Pennsylvania

Research Site, Exton, Pennsylvania

Research Site, East Providence, Rhode Island

Research Site, Providence, Rhode Island

Research Site, Charleston, South Carolina

Research Site, Columbia, South Carolina

Research Site, Chattanooga, Tennessee

Research Site, Knoxville, Tennessee

Research Site, Nashville, Tennessee

Research Site, Arlington, Texas

Research Site, Austin, Texas

Research Site, Dallas, Texas

Research Site, Houston, Texas

Research Site, Humble, Texas

Research Site, Lewisville, Texas

Research Site, Pasadena, Texas

Research Site, Pearland, Texas

Research Site, San Antonio, Texas

Research Site, Salt Lake City, Utah

Research Site, Burlington, Vermont

Research Site, Arlington, Virginia

Research Site, Manassas, Virginia

Research Site, Newport News, Virginia

Research Site, Richmond, Virginia

Research Site, Woodbridge, Virginia

Research Site, Seattle, Washington

Research Site, Buenos Aires, Not set

Research Site, Caba, Not set

Research Site, Ciudad Autonoma de Bs As, Not set

Research Site, Ciudad de Buenos Aires, Not set

Research Site, Cordoba, Not set

Research Site, Córdoba, Not set

Research Site, La Plata, Not set

Research Site, Lanus Este, Not set

Research Site, Lanus, Not set

Research Site, Mar del Plata, Not set

Research Site, Rosario, Not set

Research Site, San Nicolás, Not set

Research Site, Santa Fe, Not set

Research Site, Santiago Del Estero, Not set

Research Site, Temperley, Not set

Research Site, Adelaide, Not set

Research Site, Darlinghurst, Not set

Research Site, Elizabeth Vale, Not set

Research Site, Gosford, Not set

Research Site, Perth, Not set

Research Site, Southport, Not set

Research Site, st Leonards, Not set

Research Site, Wollongong, Not set

Research Site, Aalst, Not set

Research Site, Brussel, Not set

Research Site, Genk, Not set

Research Site, Hasselt, Not set

Research Site, Ieper, Not set

Research Site, Jette, Not set

Research Site, Kortrijk, Not set

Research Site, Leuven, Not set

Research Site, Liège, Not set

Research Site, Mechelen, Not set

Research Site, Namur, Not set

Research Site, Roeselare, Not set

Research Site, Ronse, Not set

Research Site, Sint-Truiden, Not set

Research Site, Barretos, Not set

Research Site, Belem, Not set

Research Site, Brasilia, Not set

Research Site, Campina Grande do Sul, Not set

Research Site, Campinas, Not set

Research Site, Curitiba, Not set

Research Site, Fortaleza, Not set

Research Site, Joinville, Not set

Research Site, Natal, Not set

Research Site, Porto Alegre, Not set

Research Site, Rio de Janeiro, Not set

Research Site, São José do Rio Preto, Not set

Research Site, São Paulo, Not set

Research Site, Byala, Not set

Research Site, Dupnitsa, Not set

Research Site, Gabrovo, Not set

Research Site, Gotse Delchev, Not set

Research Site, Kozloduy, Not set

Research Site, Lom, Not set

Research Site, Pernik, Not set

Research Site, Plovdiv, Not set

Research Site, Ruse, Not set

Research Site, Sandanski, Not set

Research Site, Sliven, Not set

Research Site, Sofia, Not set

Research Site, Varna, Not set

Research Site, Veliko Tarnovo, Not set

Research Site, Yambol, Not set

Research Site, Edmonton, Alberta

Research Site, Surrey, British Columbia

Research Site, Vancouver, British Columbia

Research Site, Winnipeg, Manitoba

Research Site, St. John, New Brunswick

Research Site, Halifax, Nova Scotia

Research Site, London, Ontario

Research Site, Oshawa, Ontario

Research Site, Sarnia, Ontario

Research Site, Toronto, Ontario

Research Site, Waterloo, Ontario

Research Site, Laval, Quebec

Research Site, Montreal, Quebec

Research Site, Montréal, Quebec

Research Site, Quebec, Not set

Research Site, Araucania, Not set

Research Site, Santiago, Not set

Research Site, Valdivia, Not set

Research Site, Victoria, Not set

Research Site, Viña del Mar, Not set

Research Site, Baotou, Not set

Research Site, Beijing, Not set

Research Site, Changsha, Not set

Research Site, Changzhou, Not set

Research Site, Chengdu, Not set

Research Site, Chongqing, Not set

Research Site, Dongwan, Not set

Research Site, Guangzhou, Not set

Research Site, Hefei, Not set

Research Site, Hengyang, Not set

Research Site, Huaian, Not set

Research Site, Jiaxing, Not set

Research Site, Jinan, Not set

Research Site, Jining, Not set

Research Site, Lanzhou, Not set

Research Site, Linhai, Not set

Research Site, Nanchang, Not set

Research Site, Nanning, Not set

Research Site, Ningbo, Not set

Research Site, Panjin, Not set

Research Site, Pingxiang, Not set

Research Site, Shanghai, Not set

Research Site, Shantou, Not set

Research Site, Shenyang, Not set

Research Site, Shenzhen, Not set

Research Site, Suzhou, Not set

Research Site, Tianjin, Not set

Research Site, Wuhan, Not set

Research Site, Wuxi, Not set

Research Site, Xi'an, Not set

Research Site, Xianyang, Not set

Research Site, Yantai, Not set

Research Site, Yinchuan, Not set

Research Site, Zhengzhou City, Not set

Research Site, Zhongshan, Not set

Research Site, Zhuzhou, Not set

Research Site, Zigong, Not set

Research Site, Barranquilla, Not set

Research Site, Bogota, Not set

Research Site, Cali, Not set

Research Site, Medellin, Not set

Research Site, Medellín, Not set

Research Site, Monteria, Not set

Research Site, Pasto, Not set

Research Site, Brandys nad Labem, Not set

Research Site, Brandýs nad Labem, Not set

Research Site, Frýdek-Místek, Not set

Research Site, Jilemnice, Not set

Research Site, Krnov, Not set

Research Site, Mladá Boleslav, Not set

Research Site, Nachod, Not set

Research Site, Olomouc, Not set

Research Site, Plzeň, Not set

Research Site, Praha 10, Not set

Research Site, Praha 6, Not set

Research Site, Praha, Not set

Research Site, Slany, Not set

Research Site, Aalborg, Not set

Research Site, Aarhus, Not set

Research Site, Copenhagen E, Not set

Research Site, Herlev, Not set

Research Site, Herning, Not set

Research Site, Holbæk, Not set

Research Site, Kolding, Not set

Research Site, Alexandria, Not set

Research Site, Cairo, Not set

Research Site, Dakahlia, Not set

Research Site, Amiens Cedex 1, Not set

Research Site, Bordeaux, Not set

Research Site, BREST cedex, Not set

Research Site, Clermont-Ferrand, Not set

Research Site, Creteil, Not set

Research Site, La Roche Sur Yon, Not set

Research Site, Limoges, Not set

Research Site, Lyon Cedex 03, Not set

Research Site, Marseille cedex 6, Not set

Research Site, Marseille, Not set

Research Site, Nantes cedex 1, Not set

Research Site, Nice, Not set

Research Site, Nimes, Not set

Research Site, Paris, Not set

Research Site, Pierre Bénite, Not set

Research Site, Quimper, Not set

Research Site, Reims, Not set

Research Site, Rouen, Not set

Research Site, Saint-Priest-en-Jarez, Not set

Research Site, Strasbourg, Not set

Research Site, Tours, Not set

Research Site, Vandoeuvre-Les-Nancy, Not set

Research Site, Bad Homburg, Not set

Research Site, Bamberg, Not set

Research Site, Berlin, Not set

Research Site, Bochum, Not set

Research Site, Brandenburg an der Havel, Not set

Research Site, Dresden, Not set

Research Site, Essen, Not set

Research Site, Friedrichsthal, Not set

Research Site, Görlitz, Not set

Research Site, Göttingen, Not set

Research Site, Hamburg, Not set

Research Site, Hannover, Not set

Research Site, Heidelberg, Not set

Research Site, Herne, Not set

Research Site, Karlsburg, Not set

Research Site, Karlsruhe, Not set

Research Site, Landshut, Not set

Research Site, Mainz, Not set

Research Site, Obertshausen, Not set

Research Site, Offenbach am Main, Not set

Research Site, Potsdam, Not set

Research Site, Reinfeld (Holstein), Not set

Research Site, Rostock, Not set

Research Site, Rotenburg (Wümme), Not set

Research Site, Stuttgart, Not set

Research Site, Ulm, Not set

Research Site, Wermsdorf, Not set

Research Site, Zwenkau, Not set

Research Site, Alexandroupolis, Not set

Research Site, Athens, Not set

Research Site, Heraclion, Not set

Research Site, Ioannina, Not set

Research Site, Patras, Not set

Research Site, Thessaloniki, Not set

Research Site, Budapest, Not set

Research Site, Dunaujvaros, Not set

Research Site, Encs, Not set

Research Site, Győr, Not set

Research Site, Kaposvár, Not set

Research Site, Nyiregyhaza, Not set

Research Site, Nyíregyháza, Not set

Research Site, Szeged, Not set

Research Site, Szolnok, Not set

Research Site, Székesfehérvár, Not set

Research Site, Zalaegerszeg, Not set

Research Site, Bangalore, Not set

Research Site, Belagavi, Not set

Research Site, Hyderabad, Not set

Research Site, Kolkata, Not set

Research Site, Madurai, Not set

Research Site, Mumbai, Not set

Research Site, New Delhi, Not set

Research Site, Pune, Not set

Research Site, Vijayawada, Not set

Research Site, Afula, Not set

Research Site, Ashdod, Not set

Research Site, Be'er Ya'akov, Not set

Research Site, Haifa, Not set

Research Site, Jerusalem, Not set

Research Site, Kfar-Saba, Not set

Research Site, Nahariya, Not set

Research Site, Petah Tikva, Not set

Research Site, Rehovot, Not set

Research Site, Tel Aviv, Not set

Research Site, Tiberias, Not set

Research Site, Bassano del Grappa, Not set

Research Site, Bologna, Not set

Research Site, Desio, Not set

Research Site, Foggia, Not set

Research Site, Genoa, Not set

Research Site, Modena, Not set

Research Site, Napoli, Not set

Research Site, Novara, Not set

Research Site, Padova, Not set

Research Site, Pavia, Not set

Research Site, Pisa, Not set

Research Site, Pordenone, Not set

Research Site, Roma, Not set

Research Site, Rozzano, Not set

Research Site, Torino, Not set

Research Site, Tradate, Not set

Research Site, Aira-City, Not set

Research Site, Amagasaki-shi, Not set

Research Site, Beppu-shi, Not set

Research Site, Chigasaki-shi, Not set

Research Site, Fujinomiya-shi, Not set

Research Site, Hakodate-shi, Not set

Research Site, Hamamatsu-shi, Not set

Research Site, Higashihiroshima-shi, Not set

Research Site, Iizuka-shi, Not set

Research Site, Inashiki-gun, Not set

Research Site, Itabashi-ku, Not set

Research Site, Iwata-shi, Not set

Research Site, Kagoshima, Not set

Research Site, Kamakura-shi, Not set

Research Site, Kanazawa-shi, Not set

Research Site, Kashiwara-shi, Not set

Research Site, Kasugai-shi, Not set

Research Site, Kita-ku, Not set

Research Site, Kitakyushu-shi, Not set

Research Site, Kitakyushu, Not set

Research Site, Kobe-shi, Not set

Research Site, Kumagaya-shi, Not set

Research Site, Kurashiki shi, Not set

Research Site, Kuse-gun, Not set

Research Site, Kuwana-shi, Not set

Research Site, Kyoto-shi, Not set

Research Site, Matsusaka-shi, Not set

Research Site, Matsuyama-city, Not set

Research Site, Meguro-ku, Not set

Research Site, Minato-ku, Not set

Research Site, Minokamo shi, Not set

Research Site, Miyakonojo-shi, Not set

Research Site, Morioka-shi, Not set

Research Site, Nagaoka-shi, Not set

Research Site, Naka, Not set

Research Site, Narita-shi, Not set

Research Site, Obihiro-shi, Not set

Research Site, Oita-shi, Not set

Research Site, Ome, Not set

Research Site, Omihachiman-shi, Not set

Research Site, Osaka-shi, Not set

Research Site, Osaka, Not set

Research Site, Saga-shi, Not set

Research Site, Sapporo-shi, Not set

Research Site, Sendai-shi, Not set

Research Site, Shibuya-ku, Not set

Research Site, Tanabe-shi, Not set

Research Site, Toyoake-shi, Not set

Research Site, Toyohashi-shi, Not set

Research Site, Tsu-shi, Not set

Research Site, Yaizu-shi, Not set

Research Site, Yokohama-shi, Not set

Research Site, Yoshida-gun, Not set

Research Site, Ansan-si, Not set

Research Site, Anyang-si, Not set

Research Site, Busan, Not set

Research Site, Cheonan-si, Not set

Research Site, Goyang-si, Not set

Research Site, Gwangju, Not set

Research Site, Seongnam-si, Not set

Research Site, Seoul, Not set

Research Site, Wonju-si, Not set

Research Site, Yangsan-si, Not set

Research Site, Ampang, Not set

Research Site, Cheras, Not set

Research Site, Ipoh, Not set

Research Site, Kajang, Not set

Research Site, Kota Bharu, Not set

Research Site, Kuala Lumpur, Not set

Research Site, Seremban, Not set

Research Site, Seri Manjung, Not set

Research Site, Chihuahua, Not set

Research Site, Cuauhtemoc, Not set

Research Site, Cuauhtémoc, Not set

Research Site, D.F, Not set

Research Site, Durango, Not set

Research Site, Guadalajara, Not set

Research Site, Mazatlán, Not set

Research Site, Merida, Not set

Research Site, San Luis Potosí, Not set

Research Site, Veracruz, Not set

Research Site, Zapopan, Not set

Research Site, Amersfoort, Not set

Research Site, Amsterdam, Not set

Research Site, Dordrecht, Not set

Research Site, Groningen, Not set

Research Site, Hilversum, Not set

Research Site, Leiden, Not set

Research Site, Maastricht, Not set

Research Site, Nieuwegein, Not set

Research Site, Zwolle, Not set

Research Site, Arequipa, Not set

Research Site, Bellavista, Not set

Research Site, Chorrillos, Not set

Research Site, Lima, Not set

Research Site, LIma, Not set

Research Site, Lima, Not set

Research Site, Piura, Not set

Research Site, Cebu City, Not set

Research Site, Davao City, Not set

Research Site, Iloilo City, Not set

Research Site, Laguna, Not set

Research Site, Manila, Not set

Research Site, Quezon City, Not set

Research Site, San Fernando, Not set

Research Site, Białystok, Not set

Research Site, Gdynia, Not set

Research Site, Grodzisk Mazowiecki, Not set

Research Site, Jasło, Not set

Research Site, Katowice, Not set

Research Site, Krakow, Not set

Research Site, Kraków, Not set

Research Site, Lublin, Not set

Research Site, Piaseczno, Not set

Research Site, Poznań, Not set

Research Site, Radom, Not set

Research Site, Rzeszów, Not set

Research Site, Szczecin, Not set

Research Site, Tczew, Not set

Research Site, Warszawa, Not set

Research Site, Wrocław, Not set

Research Site, Łódź, Not set

Research Site, Świecie, Not set

Research Site, Żywiec, Not set

Research Site, Brasov, Not set

Research Site, Bucharest, Not set

Research Site, Bucureşti, Not set

Research Site, Cluj Napoca, Not set

Research Site, Craiova, Not set

Research Site, Oradea, Not set

Research Site, Suceava, Not set

Research Site, Timisoara, Not set

Research Site, Al-Ahsa, Not set

Research Site, Dammam, Not set

Research Site, Riyadh/MENA, Not set

Research Site, Riyadh, Not set

Research Site, Belgrade, Not set

Research Site, Kragujevac, Not set

Research Site, Nis, Not set

Research Site, Novi Sad, Not set

Research Site, Singapore, Not set

Research Site, Košice, Not set

Research Site, Kráľovský Chlmec, Not set

Research Site, Myjava, Not set

Research Site, Nitra, Not set

Research Site, Presov, Not set

Research Site, Prešov, Not set

Research Site, Puchov, Not set

Research Site, Zilina, Not set

Research Site, Benoni, Not set

Research Site, Bloemfontein, Not set

Research Site, Cape Town, Not set

Research Site, Durban, Not set

Research Site, Lenasia, Not set

Research Site, Midrand, Not set

Research Site, Newton, Not set

Research Site, Parow, Not set

Research Site, A Coruña, Not set

Research Site, Almeria, Not set

Research Site, Badalona, Not set

Research Site, L' Hospitalet De Llobregat, Not set

Research Site, Majadahonda, Not set

Research Site, Málaga, Not set

Research Site, Palma deMallorca, Not set

Research Site, Pamplona, Not set

Research Site, Sevilla, Not set

Research Site, Valencia, Not set

Research Site, Danderyd, Not set

Research Site, Huddinge, Not set

Research Site, Karlstad, Not set

Research Site, Linköping, Not set

Research Site, Uppsala, Not set

Research Site, Växjö, Not set

Research Site, New Taipei, Not set

Research Site, Taichung City, Not set

Research Site, Taichung, Not set

Research Site, Taipei City, Not set

Research Site, Taipei, Not set

Research Site, Taoyuan, Not set

Research Site, Yung Kang City, Not set

Research Site, Bangkok, Not set

Research Site, Banphaeo, Not set

Research Site, Hat Yai, Not set

Research Site, Khon Kaen, Not set

Research Site, Mueang, Not set

Research Site, Phutthamonthon, Not set

Research Site, Ubonratchathani, Not set

Research Site, Adana, Not set

Research Site, Adapazarı, Not set

Research Site, Altındağ, Not set

Research Site, Ankara, Not set

Research Site, Antalya, Not set

Research Site, Haliliye, Not set

Research Site, Kahramanmaras, Not set

Research Site, Kayseri, Not set

Research Site, Kocaeli, Not set

Research Site, Sahinbey, Not set

Research Site, Chernivtsі, Not set

Research Site, Ivano-Frankivsk, Not set

Research Site, Kyiv, Not set

Research Site, Ternopil, Not set

Research Site, Uzhhorod, Not set

Research Site, Vinnytsia, Not set

Research Site, Vinnytsya, Not set

Research Site, Zhytomyr, Not set

Research Site, Bradford, Not set

Research Site, Bristol, Not set

Research Site, Canterbury, Not set

Research Site, Cardiff, Not set

Research Site, Dundee, Not set

Research Site, Glasgow, Not set

Research Site, Hownslow, Not set

Research Site, London, Not set

Research Site, Salford, Not set

Research Site, Southampton, Not set

Research Site, Swansea, Not set

Research Site, Da Nang, Not set

Research Site, Hai Phong, Not set

Research Site, Hanoi, Not set

Research Site, Hcmc, Not set

Research Site, Ho Chi Minh City, Not set

Research Site, Ho Chi Minh, Not set

Conditions: Chronic Kidney Disease and Hypertension

Learn More ›

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

NCT05051033

Recruiting

This is a prospective, multicenter, open-label, randomized trial comparing mitral valve (MV) transcatheter edge-to-edge repair (TEER) to surgical repair (1:1 ratio) in patients with primary, degenerative mitral regurgitation (MR). The trial will be conducted in the U.S., Canada, Germany, Spain, Belgium and the United Kingdom, and is designed as a strategy trial. Thus, all devices legally marketed for TEER of primary degenerative MR in a particular country are eligible to be used in this trial.

Gender:

ALL

Ages:

60 years and above

Trial Updated:

08/14/2025

Locations: Keck Hospital of the University of Southern California, Los Angeles, California +57 locations

Keck Hospital of the University of Southern California, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

University of California San Francisco, San Francisco, California

Stanford University, Stanford, California

Piedmont Heart Institute, Atlanta, Georgia

Emory University, Atlanta, Georgia

Ochsner Clinic, New Orleans, Louisiana

Maine Medical Center, Portland, Maine

The Johns Hopkins Hospital, Baltimore, Maryland

Massachusetts General Hospital, Boston, Massachusetts

Brigham and Women's, Boston, Massachusetts

University of Michigan Hospital, Ann Arbor, Michigan

Saint Luke's Hospital of Kansas City/MidAmerica Heart and Lung Surgeons, Kansas City, Missouri

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Nyph/Cumc, New York, New York

Weill Cornell Medicine/ New York-Presbyterian Hospital, New York, New York

Northwell Health, New York, New York

Duke University Hospital, Durham, North Carolina

Cleveland Clinic, Cleveland, Ohio

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Baylor, Scott and White, Dallas, Texas

University of Virginia Medical Center, Charlottesville, Virginia

West Virginia University Hospital, Morgantown, West Virginia

University of British Columbia, Providence Health Care, St. Paul's Hospital, Vancouver, British Columbia

London Health Sciences, London, Ontario

University of Ottawa Heart Institute, Ottawa, Ontario

Unity Health Toronto (St. Michael's Hospital), Toronto, Ontario

Institut Universitaire de Cardiologie et de Pneumologie de Quebec (Laval University), Quebec City, Quebec

Universitätsklinikum Köln, Köln, Berlin-kölnische Allee

Herz- und Diabeteszentrum NRW, Bad Oeynhausen, North Rhine-Westphalia

Kerckhoff Klinik Bad Nauheim, Bad Nauheim, Not set

Schüchtermann-Klinik Bad Rothenfelde, Bad Rothenfelde, Not set

Deutsches Herzzentrum der Charité, Berlin, Not set

Universitätsklinikum Frankfurt, Frankfurt, Not set

Universitätsklinikum Freiburg, Freiburg, Not set

Asklepios Klinik St. Georg Hamburg, Hamburg, Not set

Universitätsklinikum Hamburg Eppendorf, Hamburg, Not set

Universitätsklinikum Heidelberg, Heidelberg, Not set

Universitätsklinikum Jena, Jena, Not set

Universitätsklinikum Schleswig-Holstein Campus Kiel, Kiel, Not set

Herzzentrum Leipzig, Leipzig, Not set

Universitätsklinikum Schleswig-Holstein Campus Lübeck, Lübeck, Not set

Deutsches Herzzentrum München, München, Not set

Hospital Alvaro Cunqueiro, Vigo, Galacia

Hospital Clinic De Barcelona, Barcelona, Not set

Hospital Clínico San Carlos, Madrid, Not set

Hospital Central de Asturias, Oviedo, Not set

Royal Papworth Hospital NHS Foundation Trust, Cambridge, England

The Leeds Teaching Hospitals NHS Trust, Leeds, England

King's College Hospital NHS Foundation Trust, London, England

Royal Brompton and Harefield Guy's and St Thomas' NHS Foundation Trust, London, England

St. Thomas Guy's and St Thomas' NHS Foundation Trust, London, England

Manchester University NHS Foundation Trust, Manchester, England

University Hospitals Sussex NHS Foundation Trust, Worthing, West Sussex

Golden Jubilee University National Hospital, Clydebank, Not set

Barts Health NHS Trust, London, Not set

South Tees Hospitals NHS Foundation Trust, Middlesbrough, Not set

Conditions: Mitral Valve Regurgitation

Learn More ›

A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC in Adults With Ocular Myasthenia Gravis

NCT06558279

Recruiting

The purpose of this study is to evaluate the efficacy and safety of efgartigimod PH20 SC given by a pre-filled syringe in adult patients with ocular myasthenia gravis. The study consists of a part A (approximately 7 weeks) and a part B (up to 2 years). In part A, half of the participants will receive efgartigimod PH20 SC and the other half will receive placebo. In part B, all participants will receive efgartigimod PH20 SC. The participants will be in the study for about up to 2 years and 12 week... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: HonorHealth Neurology - Bob Bové Neuroscience Institute, Scottsdale, Arizona +77 locations

HonorHealth Neurology - Bob Bové Neuroscience Institute, Scottsdale, Arizona

Neurology Offices of South Florida, Boca Raton, Florida

SFM Clinical Research, LLC, Boca Raton, Florida

Neurology Associates PA, Maitland, Florida

University of South Florida, Tampa, Florida

Northwestern Memorial Hospital, Chicago, Illinois

Robert Wood Johnson Medical School, New Brunswick, New Jersey

Duke Neurological Disorders Clinic, Durham, North Carolina

Cleveland Clinic, Cleveland, Ohio

Martha Morehouse Medical plaza, Columbus, Ohio

National Neuromuscular Research Institute, Austin, Texas

Box Hill Hospital, Box Hill, Not set

The Alfred Hospital, Melbourne, Not set

Gold Coast University Hospital, Southport, Not set

Universitätsklinikum AKH Wien, Vienna, Not set

UZ Leuven, Leuven, Not set

Hôpital de la Citadelle, Liège, Not set

Maritime Neurology, Halifax, Not set

Ottawa Hospital Research Institute, Ottawa, Not set

Xiangya Hospital Central South University, Changsha, Not set

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Not set

The First Affiliated Hospital of Chongqing Medical University, Chongqing, Not set

Fujian Medical University Union Hospital, Fuzhou, Not set

Guangdong Province Traditional Chinese Medical Hospital, Guangzhou, Not set

The First Affiliated Hospital of Guangzhou University Chinese Medicine, Guangzhou, Not set

Qilu Hospital of Shandong University, Jinan, Not set

The First Affiliated Hospital of Nanchang University - Xianghu Campus, Nanchang, Not set

Huashan Hospital Fudan University, Shanghai, Not set

Shijiazhuang People's Hospital - Fangbeilu Campus, Shijiazhuang, Not set

Tongji Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Not set

Renmin Hospital of Wuhan University - Main Campus, Wuhan, Not set

Cyprus Institute of Neurology and Genetics, Egkomi, Not set

Fakultni nemocnice Brno, Brno, Not set

Nemocnice Pardubickeho kraje, a.s., Pardubicka nemocnice, Pardubice, Not set

Aarhus Universitetshospital, Aarhus N, Not set

Rigshospitalet, København, Not set

Turun Yliopistollinen Keskussairaala, Turku, Not set

Petre Sarajishvili Institute of Neurology, Tbilisi, Not set

New Hospitals, Tbilisi, Not set

Pineo Medical Ecosystem, Tbilisi, Not set

LLC Caucasus Medical Centre, Tbilisi, Not set

Universität Georg August, Göttingen, Not set

Eginitio Hospital, Athens, Not set

University General Hospital of Patras, Patras, Not set

Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Not set

Azienda Ospedaliero-Universitaria Sant'Andrea, Roma, Not set

Chiba University Hospital, Chuo-Ku, Not set

Kyushu University Hospital, Fukuoka, Not set

General Hanamaki Hospital, Hanamaki-shi, Not set

Hiroshima University Hospital, Hiroshima, Not set

Saitama Medical Center, Kawagoe, Not set

National Hospital Organization Utano National Hospital, Kyoto-Shi, Not set

IUHW Narita Hospital, Narita, Not set

National Hospital Organization Hokkaido Medical Center, Sapporo-Shi, Not set

Tokyo Medical University Hospital, Shinjuku-Ku, Not set

Osaka University Hospital, Suita-Shi, Not set

Kyungpook National University Chilgok hospital, Daegu, Not set

Korea University Anam Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Leids Universitair Medisch Centrum, Leiden, Not set

MICS Centrum Medyczne Bydgoszcz, Bydgoszcz, Not set

Centrum Medyczne Neurologia Slaska, Katowice, Not set

SP ZOZ Szpital Uniwersytecki, Kraków, Not set

Krakowska Akademia Neurologii, Kraków, Not set

CLINIREM Sp z o.o., Lublin, Not set

University Clinical Center of Serbia, Belgrade, Not set

University Clinical Center Nis, Nis, Not set

Hospital Universitario Vall d'Hebron, Barcelona, Not set

Hospital del Mar, Barcelona, Not set

Hospital Clinico San Carlos, Madrid, Not set

Hospital Universitario Ramon y Cajal, Madrid, Not set

Hospital Universitario de Donostia, San Sebastián, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Sahlgrenska Universitetssjukhuset, Göteborg, Not set

Royal Sussex County Hospital, Brighton, Not set

Panthera Biopartners - Glasgow, Glasgow, Not set

Dementech Neurosciences Clinical Academic Centre, London, Not set

Conditions: Myasthenia Gravis, Ocular

Learn More ›

A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors

NCT05983133

Recruiting

This study will test the safety of a drug called PF-08046052/SGN-EGFRd2 in participants with advanced solid tumors. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease. Participants will have cancer that cannot be removed (unresectable) or has spread through the body (metastatic). This study will have three parts. Parts A and B of the study will find out how much PF-08046052/SGN-EGFRd2 should be given to participants.... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Ronald Reagan UCLA Medical Center, Los Angeles, California +22 locations

Ronald Reagan UCLA Medical Center, Los Angeles, California

UCLA Hematology/Oncology, Los Angeles, California

Santa Monica UCLA Medical Center & Orthopaedic Hospital, Santa Monica, California

UCLA Hematology/Oncology - Santa Monica, Santa Monica, California

Moffitt Cancer Center McKinley Hospital, Tampa, Florida

Moffitt Cancer Center, Tampa, Florida

University of Iowa, Iowa City, Iowa

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Karmanos Cancer Institute Weisberg Cancer Treatment Center, Farmington Hills, Michigan

Hackensack University Medical Center, Hackensack, New Jersey

John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey

Atrium Health Wake forest Baptist, Winston-Salem, North Carolina

Wake Forest Baptist Medical Center / Wake Forest University, Winston-Salem, North Carolina

University Hospitals Cleveland Medical Center, Cleveland, Ohio

Providence Cancer Institute Franz Clinic, Portland, Oregon

Providence Portland Medical Center, Portland, Oregon

MD Anderson Cancer Center - University of Texas, Houston, Texas

The University of Texas MD Anderson Cancer Center, Houston, Texas

Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah

Huntsman Cancer Institute, University Of Utah, Salt Lake City, Utah

University College London Hospital, NIHR UCLH Clinical Research Facility, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Conditions: Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung, Squamous Cell Carcinoma of the Head and Neck, Pancreatic Ductal Adenocarcinoma

Learn More ›

Seizure Identification on the Intensive Care Unit (ICU)

NCT07136298

Recruiting

The aim of this project is to assess the ability of different groups of National Heath Service (NHS) professionals to correctly identify clinical seizures, and distinguish them from other movements commonly seen in the ICU environment, when shown digital video recordings only. Patients on the ICU are at risk of having seizures, however also commonly make other movements, including shivering, jerking, tics and tremors. An Electroencephalogram (EEG) records the brain wave activity and can help distinguish epileptic seizures from other movements. In a study by Bendadis et al (2010), 52 video-EEGs were reviewed containing "possible seizures" on the ICU. They found only 27% recorded actual epileptic events, with the other 73% having a range of other movements. Malone et al (2009) studied accuracy of diagnosis of 20 video recordings of clinical episodes on the neonatal unit, comparing different staff groups. They found no significant difference between Doctors and Nurses in correctly identifying seizures, however found that accuracy of diagnosis was generally poor. Clinical scientists are currently expanding their roles and responsibilities across Neurophysiology, including giving consultant-level advice on EEG investigations. EEG recordings on the ICU are often obscured by excessive, unavoidable electrical/movement artefacts caused by equipment such ventilators and pumps, and patient factors such as position, breathing artefact and suctioning. These make the EEG difficult to interpret (Boggs 2021). Assessing the clinical signs and symptoms which we may see in ICU patients, in the absence of interpretable EEG, is an essential skill. This study aims to assess Clinical Scientists skills at clinical interpretation, in comparison with other staff groups in the ICU setting. Staff will be asked to watch video clips of events captured in the ICU, and tell us whether they think they are seizures or not, and explain their thought process behind the decision. Read Less

Gender:

ALL

Ages:

All

Trial Updated:

08/14/2025

Locations: Nottingham University Hospitals, Nottingham, Nottinghamshire

Conditions: Seizures

Learn More ›

Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)

NCT06814145

Recruiting

Researchers are looking for new ways to treat people with a type of pulmonary hypertension called combined postcapillary and precapillary pulmonary hypertension (Cpc-PH). This study focuses on Cpc-PH that is caused by heart failure with preserved ejection fraction (HFpEF). Researchers want to know if the study treatment, sotatercept, can treat people with Cpc-PH caused by HFpEF. This is an extension study, which means people who took part in a certain study on sotatercept for Cpc-PH (called a p... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Pulmonary Associates, PA ( Site 1008), Phoenix, Arizona +27 locations

Pulmonary Associates, PA ( Site 1008), Phoenix, Arizona

Jeffrey S. Sager, MD Medical Corporation ( Site 1060), Santa Barbara, California

Stanford University Medical Center ( Site 1024), Stanford, California

South Denver Cardiology Associates ( Site 1091), Littleton, Colorado

Norton Pulmonary Specialists ( Site 1066), Louisville, Kentucky

University Of Nebraska Medical Center ( Site 1053), Omaha, Nebraska

Weill Cornell Medical Center ( Site 1046), New York, New York

Lankenau Medical Center ( Site 1089), Wynnewood, Pennsylvania

Statcare Pulmonary Consultants ( Site 1031), Knoxville, Tennessee

Intermountain Medical Center ( Site 1079), Murray, Utah

Inova Heart and Vascular Institute ( Site 1078), Falls Church, Virginia

Pulmonary Associates of Richmond - West Broad Street ( Site 1069), Richmond, Virginia

Centre Hospitalier Universitaire de Nice - Hopital Pasteur ( Site 0206), Nice, Alpes-Maritimes

Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes ( Site 0205), Saint-Herblain, Loire-Atlantique

Centre Hopitalier Universitaire d'Angers ( Site 0204), Angers, Maine-et-Loire

CHU de Rouen ( Site 0203), Rouen, Seine-Maritime

Hôpitaux Universitaires Paris Sud - Hôpital Bicêtre ( Site 0202), Le Kremlin-Bicêtre, Val-de-Marne

Thoraxklinik-Heidelberg gGmbH ( Site 0309), Heidelberg, Baden-Wurttemberg

ZIV Medical Center ( Site 0400), Safed, Not set

Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII ( Site 0502), Bergamo, Lombardia

Fondazione IRCCS Policlinico San Matteo ( Site 0501), Pavia, Not set

AOU Policlinico Umberto I ( Site 0500), Roma, Not set

Hospital Clinic I Provincial de Barcelona ( Site 0701), Barcelona, Not set

Hospital Universitario 12 de Octubre ( Site 0702), Madrid, Not set

Hospital Universitario Virgen Macarena ( Site 0705), Sevilla, Not set

HOSPITAL GENERAL UNIVERSITARIO DE TOLEDO ( Site 0703), Toledo, Not set

Sahlgrenska Universitetssjukhuset-Cardiology Research Unit ( Site 0800), Goteborg, Vastra Gotalands Lan

Hammersmith Hospital-Department of Cardiology ( Site 0900), London, London, City Of

Conditions: Hypertension, Pulmonary

Learn More ›

Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)

NCT06843239

Recruiting

The study is a Phase 2, multi-center, randomized, double-blind, placebo-controlled study to evaluate the effects of tibulizumab over 24 weeks (Period 1) in adult participants with systemic sclerosis, followed by an open-label extension period where all active participants will receive tibulizumab and will be evaluated for an additional 28 weeks (Period 2)

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/14/2025

Locations: IRIS Research and Development LLC, Plantation, Florida +7 locations

Conditions: Systemic Sclerosis (SSc), Scleroderma

Learn More ›

A Study to Evaluate the Effect of Ceralasertib on Drug X, Drug Y and Drug Z

NCT06929260

Recruiting

The study aims to assess the effect of ceralasertib on the pharmacokinetics (PK) of Drug X, Drug Y and Drug Z in participants with advanced solid tumours.

Gender:

ALL

Ages:

Between 18 years and 65 years

Trial Updated:

08/14/2025

Locations: Research Site, Barcelona, Not set +3 locations

Conditions: Advanced Solid Tumours

Learn More ›

A Study to Learn More About the Effects and Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Aged 2 to 15 Years Old

NCT06953583

Recruiting

In this study, researchers will learn more about the effects and safety of BIIB141, also known as omaveloxolone or SKYCLARYS®. This drug has been approved, or made available for doctors to prescribe, for people with Friedreich's Ataxia (FA) who are at least 16 years old. But, it is not yet available for children and teens with FA who are younger than 16 years old. The main objective of this study is to learn how BIIB141 works in the body and about its safety in children and teens who are 2 to 15 years old. The main questions researchers want to answer in this study are: * How does BIIB141 affect the participants' FA symptoms balance and stability? * How many participants have medical problems during the study? * Are there any changes in the participants' overall health during the study? * Are there any changes in the participants' heart health? * Are there any changes in how the participants move through puberty? Puberty is the time in someone's life when their body changes from a child to an adult. Researchers will also learn more about: - How the body processes BIIB141 in children and teens This study will be done as follows: * Participants will be screened to check if they can join the study. The screening period will be up to 28 days, after which participants will check into their study research center. * There are 2 parts in this study. During Part 1, participants will take either BIIB141 or a placebo once a day. * In Part 1, participants will take BIIB141 or the placebo in a study research center on Day 1, and then at in-person visits at Week 4, Week 12, Week 26, and Week 52. On all other days, they will take BIIB141 or the placebo at home. Part 1 lasts up to 52 weeks. * During Part 2, participants from Part 1 will either continue taking BIIB141 or start it if they were taking the placebo. Part 2 will last up to 104 weeks. * In Part 1, participants will have up to 10 visits to their study research center and a phone call at Week 2. In Part 2, participants will have visits at Weeks 4, 8,12, 26, and every 26 weeks after that until they leave the study, and a phone call at Week 2. There will be a final phone call to check on the participants' health 31 days after their last dose. * Each participant will be in the study for up to about 3 years Read Less

Gender:

ALL

Ages:

Between 2 years and 15 years

Trial Updated:

08/14/2025

Locations: UCLA Neurology Outpatient Clinic at Westwood, Los Angeles, California +26 locations

UCLA Neurology Outpatient Clinic at Westwood, Los Angeles, California

Norman Fixel Institute for Neurological Diseases UF Health, Gainesville, Florida

USF Health Morsani College of Medicine Department of Neurology, Tampa, Florida

Children's Hospital of Philadelphia Buerger Center, Philadelphia, Pennsylvania

St Jude Children's Research Hospital, Memphis, Tennessee

Children's Hospital of the King's Daughters, Norfolk, Virginia

Murdoch Childrens Research Institute (MCRI), Parkville, Victoria

Universitätsklinikum Innsbruck, Innsbruck, Not set

L2 Ip - Instituto de Pesquisas Clinicas Ltda - ME, Brasília, Distrito Federal

University of Campinas (UNICAMP) School of Medical Sciences, Campinas, Sao Paulo

PSEG Centro de Pesquisa Clinica, Sao Paulo, Not set

McGill University, Montreal, Quebec

Rigshospitalet - Juliane Marie Centret (JMC) Copenhagen, Copenhagen, Not set

CHU de Montpellier - Hôpital Arnaud de Villeneuve, Montpellier, Hérault

AP-HP - Hôpital Armand Trousseau, Paris, Not set

Universitätsklinikum Aachen, Aachen, Not set

UKGM - Universitätsklinikum Giessen und Marburg GmbH - Standort Gießen, Giessen, Not set

UKE Hamburg, Hamburg, Not set

CHI at Temple Street, Dublin, Not set

Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Lazio

IRCCS Eugenio Medea - Polo. Scientifico Veneto, Conegliano, Veneto

Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Not set

Radboud Universitair Medisch Centrum, Nijmegen, Not set

Hospital Sant Joan de Deu, Espluges De Llobregat, Not set

Hospital Universitario La Paz - PPDS, Madrid, Not set

Sheffield Children's Hospital, Sheffield, South Yorkshire

University College London, Institue of Neurology, London, Not set

Conditions: Friedreich Ataxia

Learn More ›

Nipocalimab in Moderate to Severe Sjogren's Disease

NCT06741969

Recruiting

The purpose of this study is to evaluate the clinical efficacy and safety of nipocalimab in participants with moderate to severe Sjogren's disease (SjD).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: Providence Medical Foundation, Fullerton, California +121 locations

Providence Medical Foundation, Fullerton, California

Arthritis & Osteoporosis Medical Center - La Palma, La Palma, California

Providence Saint John s Health Center, Santa Monica, California

Inland Rheumatology Clinical Trials Inc., Upland, California

Denver Arthritis Clinic, Denver, Colorado

Clinical Research of West Florida Inc, Clearwater, Florida

UF Health Rheumatology, Jacksonville, Florida

Suncoast Clinical Research, New Port Richey, Florida

Sarasota Arthritis Center, Sarasota, Florida

BioResearch Partner, South Miami, Florida

Clinical Investigation Specialists - Clinic of Robert Hozman, Skokie, Illinois

Willow Rheumatology and Wellness PLLC, Willowbrook, Illinois

University of Iowa Hospital and Clinics, Iowa City, Iowa

St. Paul Rheumatology P A, Eagan, Minnesota

Atrium Health SouthPark Rheumatology, Charlotte, North Carolina

Onsite Clinical Solutions, Salisbury, North Carolina

Wright State Physicians Health Center, Fairborn, Ohio

OMRF Rheumatology Center of Excellence, Oklahoma City, Oklahoma

Altoona Center For Clinical Research, Duncansville, Pennsylvania

West Tennessee Research Institute, Jackson, Tennessee

Overlake Arthritis and Osteoporosis Center, Bellevue, Washington

Instituto Medico De Alta Complejidad (IMAC), Buenos Aires, Not set

Centro de Investigacion en Enfermedades Reumaticas CIER, Ciudad de Buenos Aires, Not set

Centro Medico Barrio Parque. Swiss Medical Group, Ciudad de Buenos Aires, Not set

Cosultorios Reumatologógicos Pampa, Ciudad de Buenos Aires, Not set

Cer Instituto Medico, Quilmes, Not set

Centro de Investigaciones Medicas Tucuman, San Miguel De Tucuman, Not set

Medizinische Universitaet Graz, Graz, Not set

LK Weinviertel Stockerau, Stockerau, Not set

Instituto D Or de Pesquisa e Ensino, Brasilia, Not set

Ceti - Centro de Estudos Em Terapias Inovadoras, Curitiba, Not set

Associacao Hospitalar Moinhos de Vento, Porto Alegre, Not set

Hospital das Clinicas de Porto Alegre, Porto Alegre, Not set

LMK Servicos Medicos S S, Porto Alegre, Not set

SER - Servicos Especializados em Reumatologia da Bahia, Salvador, Not set

Instituto D Or de Pesquisa e Ensino, Salvador, Not set

Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base, Sao Jose do Rio Preto, Not set

EBSERH Empresa de Servicos Hospitalares Hospital Samaritano, Sao Paulo, Not set

Hospital Das Clinicas Da Faculdade De Medicina Da USP, Sao Paulo, Not set

CEDOES Centro de Pesquisa Clinica e Diagnostico do Espirito Santo Ltda, Vitoria, Not set

UMHAT Kaspela, Plovdiv, Not set

Medical Center Artmed, Plovdiv, Not set

Medical Center Teodora, Ruse, Not set

Lyulin Multi Profile Hospital For Active Medical Treatment, Sofia, Not set

Diagnostic Consultative Center - DCC Equita EOOD, Varna, Not set

Beiijing Friendship Hospital, Capital Medical University, Beijing, Not set

Peking University Third Hospital, Beijing, Not set

West China Hospital Sichuan University, Chengdu, Not set

The Affiliated Hospital of Guizhou Medical University, Gui Yang Shi, Not set

The Second Affiliated Hospital of Zhejiang University College of Medicine, Hang Zhou Shi, Not set

Jinhua municipal central hospital, Jinhua, Not set

The People's Hospital of Guangxi Zhuang Autonomous Region, Nan Ning Shi, Not set

The First Affiliated Hospital of NanChang University, Nanchang, Not set

Ningbo medical center lihuili hospital, Ningbo, Not set

Shanxi Academy of Medical Sciences, Tai Yuan Shi, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Xinxiang Central Hospital, Xin Xiang Shi, Not set

Zealand University Hospital, Koge, Not set

Universitatsklinikum Carl Gustav Carus Dresden, Dresden, Not set

Hamburger Rheuma Forschungszentrum II, Hamburg, Not set

Rheumazentrum Ruhrgebiet, Herne, Not set

Medicover Muenchen Ost MVZ, Munchen, Not set

Universitaetsklinikum Wuerzburg, Wuerzburg, Not set

Betegapolo Irgalmas Rend Budai Irgalmasrendi Korhaz, Budapest, Not set

Clinexpert Kft, Budapest, Not set

Szegedi Tudomanyegyetem, Szeged, Not set

Vita Verum Medical Egeszsegugyi Szolgaltato Bt, Szekesfehervar, Not set

St. Luke's International Hospital, Chuo ku, Not set

Tokyo Metropolitan Tama Medical Center, Fuchu, Not set

National Hospital Organization Kyushu Medical Center, Fukuoka, Not set

National Hospital Organization Osaka Minami Medical Center, Kawachi Nagano, Not set

Shinkenko Clinic, Naha, Not set

Okayama City General Medical Center Okayama City Hospital, Okayama, Not set

Hokkaido University Hospital, Sapporo, Not set

Sasebo Chuo Hospital, Sasebo, Not set

Tohoku Medical And Pharmaceutical University Hospital, Sendai, Not set

Dokkyo Medical University Hospital, Shimotsuga Gun, Not set

Tokyo Metropolitan Bokutoh Hospital, Sumida ku, Not set

Nihon University Itabashi Hospital, Tokyo, Not set

Chonnam National University Hospital, Gwangju, Not set

Hanyang University Medical Center, Seoul, Not set

Konkuk University Medical Center, Seoul, Not set

The Catholic University of Korea Seoul St Mary s Hospital, Seoul, Not set

Ajou University Hospital, Suwon si, Not set

Centro Medico Nacional Siglo XXI IMSS, Ciudad de Mexico, Not set

Centro de Investigacion de Tratamientos Innovadores de Sinaloa, Culiacan, Not set

Clinica de Investigacion en Reumatologia y Obesidad, Guadalajara, Not set

Medical Care & Research SA de CV, Merida, Not set

CITER Centro de Investigacion y Tratamiento de las Enfermedades Reumaticas S A de C V, Mexico, Not set

SMIQ S de R L de C V, Queretaro, Not set

MICS Centrum Medyczne Bydgoszcz, Bydgoszcz, Not set

Szpital Uniwersytecki nr 2 im dr Jana Biziela w Bydgoszczy, Bydgoszcz, Not set

Malopolskie Badania Kliniczne Sp z o o, Krakow, Not set

Futuremeds Krakow, Krakow, Not set

Etyka Osrodek Badan Klinicznych Tomasz Pesta S K A, Olsztyn, Not set

AI Centrum Medyczne, Poznan, Not set

FutureMeds Targowek, Warsaw, Not set

MICS Centrum Medyczne Warszawa, Warszawa, Not set

Narodowy Instytut Geriatrii Reumatologii i Rehabilitacji im prof dr hab med Eleonory Reicher, Warszawa, Not set

Centrum Medyczne Oporow, Wroclaw, Not set

FutureMeds Wroclaw, Wroclaw, Not set

Uls Gaia Espinho, Vila Nova de Gaia, Not set

Spitalul Clinic Judetean de Urgenta Cluj, Cluj Napoca, Not set

Hosp. Cima Sanitas Barcelona, Barcelona, Not set

Hosp Univ Vall D Hebron, Barcelona, Not set

Hosp. de La Santa Creu I Sant Pau, Barcelona, Not set

Hosp. Gral. Juan Ramon Jimenez, Huelva, Not set

Hosp. Univ. 12 de Octubre, Madrid, Not set

Hosp. de Navarra, Pamplona, Not set

Hosp. Univ. Marques de Valdecilla, Santander, Not set

Hosp. Infanta Luisa, Sevilla, Not set

NTU Biomedical Park Hospital, Hsinchu City, Not set

Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City, Not set

Kaohsiung Veterans General Hospital, Kaohsiung, Not set

Taipei Medical University Shuang Ho Hospital, New Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Linkou Chang Gung Memorial Hospital, Taoyuan, Not set

Doncaster Royal Infirmary, Doncaster, Not set

Barts Health NHS Trust, Greater London, Not set

University Hospital Aintree, Liverpool, Not set

Peterborough City Hospital, Peterborough, Not set

Great Western Hospital, Swindon, Not set

Conditions: Sjogrens Syndrome

Learn More ›

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

NCT06422143

Recruiting

This is a phase 3 study of pembrolizumab in combination with carboplatin/taxane (paclitaxel or nab-paclitaxel) followed by pembrolizumab with or without maintenance sacituzumab tirumotecan (sac-TMT; MK-2870) in first-line treatment of metastatic squamous non-small cell lung cancer. It is hypothesized that pembrolizumab with maintenance sacituzumab tirumotecan is superior to pembrolizumab without sacituzumab tirumotecan maintenance with respect to overall survival (OS).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/14/2025

Locations: CARTI Cancer Center ( Site 0006), Little Rock, Arkansas +188 locations

CARTI Cancer Center ( Site 0006), Little Rock, Arkansas

Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center ( Site 0122), Burbank, California

Exempla Lutheran Medical Center ( Site 0119), Golden, Colorado

Intermountain Health St. Mary's Regional Hospital ( Site 0116), Grand Junction, Colorado

Mid Florida Hematology and Oncology Center ( Site 0109), Orange City, Florida

Centricity Research Columbus Cancer Center ( Site 0111), Columbus, Georgia

Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital ( Site 0001), Marietta, Georgia

University of Chicago Medical Center ( Site 0145), Chicago, Illinois

Allina Health Cancer Institute - Abbott Northwestern Hospital ( Site 0146), Minneapolis, Minnesota

New Mexico Oncology Hematology Consultants Ltd. ( Site 0123), Albuquerque, New Mexico

Thomas Jefferson University - Clinical Research Institute ( Site 0147), Philadelphia, Pennsylvania

Oncology Consultants P.A. ( Site 0124), Houston, Texas

Mays Cancer Center ( Site 0132), San Antonio, Texas

Instituto Alexander Fleming ( Site 0203), Ciudad Autónoma de Buenos Aires, Buenos Aires

Instituto de Investigaciones Clínicas Mar del Plata ( Site 0200), Mar del Plata, Buenos Aires

Instituto Médico Río Cuarto ( Site 0204), Rio Cuarto., Cordoba

Fundacion Intecnus ( Site 0205), San Carlos de Bariloche, Rio Negro

Sanatorio Parque ( Site 0201), Rosario, Santa Fe

Hospital Aleman-Oncology ( Site 0202), Buenos Aires, Not set

Ordensklinikum Linz GmbH Elisabethinen-Department of Pneumology ( Site 0720), Linz, Oberosterreich

Klinik Hietzing ( Site 0740), Wien, Not set

Standort Penzing der Klinik Ottakring-Abteilung für Atemwegs-und Lungenkrankheiten ( Site 0730), Wien, Not set

Klinik Floridsdorf-Abteilung für Innere Medizin und Pneumologie ( Site 0710), Wien, Not set

Hospital do Cancer de Pernambuco ( Site 0312), Recife, Pernambuco

Oncoclínica Oncologistas Associados ( Site 0309), Terezina, Piaui

Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 0311), Porto Alegre, Rio Grande Do Sul

Hospital Nossa Senhora da Conceição ( Site 0300), Porto Alegre, Rio Grande Do Sul

Instituto de Oncologia Saint Gallen ( Site 0304), Santa Cruz do Sul, Rio Grande Do Sul

Hospital de Base de São José do Rio Preto ( Site 0310), São José do Rio Preto, Sao Paulo

Hospital Paulistano ( Site 0307), Sao Paulo, Not set

Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 0100), Kingston, Ontario

Waterloo Regional Health Network (WRHN) ( Site 0153), Kitchener, Ontario

St. Marys Hospital Center ( Site 0105), Montreal, Quebec

McGill University Health Centre ( Site 0103), Montréal, Quebec

Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-centre-du-quebec ( Site 0106), Trois-Rivières, Quebec

Centro de Investigación del Maule ( Site 0419), Talca, Maule

FALP ( Site 0409), Santiago, Region M. De Santiago

Pontificia Universidad Catolica de Chile-Hemato-Oncology ( Site 0402), Santiago, Region M. De Santiago

Bradfordhill-Clinical Area ( Site 0407), Santiago, Region M. De Santiago

ONCOCENTRO APYS-ACEREY ( Site 0400), Viña del Mar, Valparaiso

Bradford Hill Norte ( Site 0420), Antofagasta, Not set

Beijing Cancer Hospital ( Site 2411), Beijing, Beijing

Beijing Cancer hospital-intrathoratic deparmtment II ( Site 2410), Beijing, Beijing

Peking Union Medical College Hospital ( Site 2412), Beijing, Beijing

Army Medical Center of People's Liberation Army-respiratory ( Site 2426), Chongqing, Chongqing

Fujian Provincial Cancer Hospital ( Site 2419), Fuzhou, Fujian

The First Affiliated hospital of Xiamen University-oncology ( Site 2420), Xiamen, Fujian

The First Affiliated Hospital of Guangzhou Medical University ( Site 2417), Guangzhou, Guangdong

Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( Site 2416), Guangzhou, Guangdong

Harbin Medical University Cancer Hospital-oncology of department ( Site 2415), Harbin, Heilongjiang

Henan Cancer Hospital-Pneumology department ( Site 2423), Zhengzhou, Henan

Tongji Hospital Tongji Medical,Science & Technology ( Site 2424), Wuhan, Hubei

The Second Xiangya Hospital of Central South University-Oncology ( Site 2418), Changsha, Hunan

First Huai'an Hospital Affiliated to Nanjing Medical University ( Site 2402), Huai'an, Jiangsu

Northern Jiangsu People's Hospital-General Surgery Department ( Site 2403), Yangzhou, Jiangsu

The Second Affiliated Hospital of Nanchang University-Oncology Department ( Site 2405), Nanchang, Jiangxi

The First affiliated hospital of Nanchang University (Xianghu campus) ( Site 2404), Nanchang, Jiangxi

Jilin Province Tumor Hospital-GCP office ( Site 2413), Changchun, Jilin

The First Hospital of Jilin University-Oncology ( Site 2414), Changchun, Jilin

Shanghai East Hospital ( Site 2428), Shanghai, Shanghai

Shanghai Pulmonary Hospital ( Site 2427), Shanghai, Shanghai

West China Hospital, Sichuan University ( Site 2422), Cheng Du, Sichuan

Sichuan Cancer hospital. ( Site 2421), Chengdu, Sichuan

The Affiliated Cancer Hospital of Xinjiang Medical University ( Site 2425), Urumqi, Xinjiang

The first Affiliated Hospital, Zhejiang University School of Medicine-Respiratory Department ( Site 2406), Hangzhou, Zhejiang

Sir Run Run Shaw Hospital of Zhejiang University School of Medicine-Medical Oncology ( Site 2407), Hangzhou, Zhejiang

Zhejiang Cancer Hospital-Breast Oncology ( Site 2408), Hangzhou, Zhejiang

Taizhou Hospital of Zhejiang Province ( Site 2430), Taizhou, Zhejiang

The First Affiliated Hospital of Wenzhou Medical University-Respiratory department ( Site 2409), Wenzhou, Zhejiang

Centro Cancerológico del Caribe (CECAC) ( Site 0509), Barranquilla, Atlantico

Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0501), Valledupar, Cesar

FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0500), Bogota, Distrito Capital De Bogota

Oncologos del Occidente ( Site 0504), Pereira., Risaralda

Fundación Valle del Lili-Oncology CIC ( Site 0505), Cali, Valle Del Cauca

Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0800), Brno, Brno-mesto

Nemocnice AGEL Ostrava - Vitkovice a.s.-Plicni oddeleni ( Site 0803), Ostrava-Vitkovice, Ostrava Mesto

Fakultni nemocnice Olomouc-Klinika plicnich nemoci a tuberkulozy ( Site 0802), Olomouc, Not set

Clinique Clairval ( Site 0904), Marseille, Bouches-du-Rhone

Hôpital Robert Schuman ( Site 0907), Vantoux, Lorraine

Institut de Cancérologie de l'Ouest ( Site 0908), ANGERS cedex 02, Maine-et-Loire

Sainte Catherine Institut du Cancer Avignon Provence ( Site 0902), Avignon, Vaucluse

CHD Vendee ( Site 0901), La Roche-sur-Yon, Vendee

Hôpital Saint-Louis ( Site 0906), Paris, Not set

GEFOS Gesellschaft f. onkologische Studien ( Site 1005), Dortmund, Nordrhein-Westfalen

Universitätsklinikum Schleswig-Holstein-Pneumologie ( Site 1000), Luebeck, Schleswig-Holstein

SRH Wald-Klinikum Gera-Zentrum für klinische Studien ( Site 1006), Gera, Thuringen

Charité Campus Virchow-Klinikum-Department of Infectious Diseases and Pulmonary Medicine ( Site 1003), Berlin, Not set

Bacs-Kiskun Varmegyei Oktatokorhaz ( Site 1100), Kecskemét, Bacs-Kiskun

Petz Aladar Egyetemi Oktato Korhaz ( Site 1101), Gyor, Gyor-Moson-Sopron

Jász-Nagykun-Szolnok Vármegyei Hetényi Géza Kórház-Onkologiai Kozpont ( Site 1103), Szolnok, Jasz-Nagykun-Szolnok

Reformatus Pulmonologiai Centrum ( Site 1102), Torokbalint, Pest

Zala Megyei Szent Rafael Kórház ( Site 1110), Zalaegerszeg, Zala

Országos Korányi Pulmonológiai Intézet ( Site 1104), Budapest, Not set

St. James's Hospital ( Site 1200), Dublin, Not set

Rambam Health Care Campus-Oncology Division ( Site 1302), Haifa, Not set

Shaare Zedek Medical Center ( Site 1300), Jerusalem, Not set

Rabin Medical Center ( Site 1303), Petah Tikva, Not set

Sheba Medical Center ( Site 1301), Ramat Gan, Not set

Istituto Nazionale Tumori IRCCS Fondazione Pascale-Oncologia clinica sperimentale Toraco-Polmonare ( Site 1401), Napoli, Campania

Azienda Ospedaliera S. Giovanni Addolorata-Oncologia Medica ( Site 1409), Roma, Lazio

Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1404), Milan, Lombardia

Fondazione IRCCS San Gerardo dei Tintori-Oncologia ( Site 1412), Monza, Lombardia

Istituto Clinico Humanitas-U.O di Oncologia medica ed Ematologia ( Site 1408), Rozzano, Milano

Istituto Nazionale Tumori Regina Elena-Oncologia Medica 2 ( Site 1402), Rome, Roma

Azienda Ospedaliera Spedali Civili di Brescia-Oncology ( Site 1414), Brescia, Not set

Ospedale San Martino ( Site 1407), Genova, Not set

Fondazione IRCCS Policlinico San Matteo-Oncology ( Site 1410), Pavia, Not set

Ospedale di Circolo e Fondazione Macchi Varese-Oncology ( Site 1413), Varese, Not set

Aichi Cancer Center ( Site 2502), Nagoya, Aichi

Nagoya University Hospital ( Site 2519), Nagoya, Aichi

Fujita Health University Hospital ( Site 2515), Toyoake, Aichi

Hirosaki University Hospital ( Site 2514), Hirosaki, Aomori

Ehime University Hospital ( Site 2511), Toon, Ehime

Gunma Prefectural Cancer Center ( Site 2510), Ota, Gunma

Takarazuka City Hospital ( Site 2508), Takarazuka, Hyogo

Kanazawa University Hospital ( Site 2513), Kanazawa, Ishikawa

St. Marianna University Hospital ( Site 2521), Kawasaki, Kanagawa

Kanagawa Cardiovascular and Respiratory Center ( Site 2518), Yokohama, Kanagawa

Kanagawa Cancer Center ( Site 2504), Yokohama, Kanagawa

Matsusaka Municipal Hospital ( Site 2522), Matsusaka, Mie

Sendai Kousei Hospital ( Site 2507), Sendai, Miyagi

Kansai Medical University Hospital ( Site 2503), Hirakata, Osaka

Saitama Prefectural Cancer Center ( Site 2512), Kitaadachi-gun, Saitama

Cancer Institute Hospital of JFCR ( Site 2500), Koto, Tokyo

Toho University Omori Medical Center ( Site 2520), Ota, Tokyo

National Center for Global Health and Medicine ( Site 2516), Shinjuku, Tokyo

National Hospital Organization Yamaguchi Ube Medical Center ( Site 2523), Ube, Yamaguchi

Chiba University Hospital ( Site 2517), Chiba, Not set

National Hospital Organization Kyushu Medical Center ( Site 2509), Fukuoka, Not set

Niigata Cancer Center Hospital ( Site 2505), Niigata, Not set

Osaka International Cancer Institute ( Site 2506), Osaka, Not set

The Catholic University of Korea, Incheon St. Mary's Hospital ( Site 2106), Bupyeong-gu, Incheon

Pusan National University Yangsan Hospital ( Site 2104), Yangsan-si, Kyongsangnam-do

Pusan National University Hospital ( Site 2100), Busan, Pusan-Kwangyokshi

Kyungpook National University Chilgok Hospital-Pulmonology ( Site 2102), Deagu, Taegu-Kwangyokshi

Chungnam national university hospital-Department of Internal Medicine ( Site 2107), Daejeon, Taejon-Kwangyokshi

Kyung Hee University Hospital ( Site 2101), Seoul, Not set

Asan Medical Center ( Site 2105), Seoul, Not set

Korea University Guro Hospital-Internal Medicine ( Site 2103), Seoul, Not set

Clínicas AUNA Sede Chiclayo ( Site 0604), Chiclayo, Lambayeque

Oncosalud-Clinical Research ( Site 0600), Lima, Not set

Hospital Militar Central Coronel Luis Arias Schereiber ( Site 0602), Lima, Not set

Wielkopolskie Centrum Pulmonologii i Torakochirurgii-Oddzial Onkologii Klinicznej z Pododdzialem Dz ( Site 1510), Poznań, Dolnoslaskie

Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1503), Bydgoszcz, Kujawsko-pomorskie

Regionalny Szpital Specjalistyczny im. dr. Władyslawa Biegańskiego ( Site 1513), Grudziadz, Kujawsko-pomorskie

Szpital Specjalistyczny im. Henryka Klimontowicza ( Site 1507), Gorlice, Malopolskie

Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie-Oncology Department ( Site 1515), Kraków, Malopolskie

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 1500), Warszawa, Mazowieckie

Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1501), Przemysl, Podkarpackie

Szpital Wojewódzki w Koszalinie. ( Site 1517), Poland, Zachodniopomorskie

Centrul Medical Medicover Victoria ( Site 2000), Bucharest, Bucuresti

Cardiomed SRL Cluj-Napoca ( Site 2002), Cluj-Napoca, Cluj

SC Radiotherapy Center Cluj SRL-Oncologie Medicala ( Site 2001), Florești, Cluj

Centrul de Oncologie Sfantul Nectarie-Medical ( Site 2004), Craiova, Dolj

Cabinet Medical Oncomed ( Site 2005), Timisoara, Timis

SC ONCO CARD SRL ( Site 2007), Brasov, Not set

Clinica Polisano ( Site 2008), Sibiu, Not set

CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 1703), Santiago de Compostela, Galicia

Hospital Insular de Gran Canaria-Oncology ( Site 1701), Las Palmas de Gran Canaria, Las Palmas

Hospital Quirón Málaga ( Site 1704), Málaga, Malaga

Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 1700), Barcelona, Not set

Hospital Universitario Fundación Jiménez Díaz-Oncology & Hematology ( Site 1702), Madrid, Not set

Hospital Universitario Virgen de Valme-Departamento de Oncologia ( Site 1705), Sevilla, Not set

National Taiwan University Cancer Center (NTUCC) ( Site 2209), Taipei City, Taipei

Taoyuan General Hospital ( Site 2203), Taoyuan City, Taoyuan

Chang Gung Memorial Hospital at Kaohsiung ( Site 2207), Kaohsiung, Not set

Taichung Veterans General Hospital ( Site 2204), Taichung, Not set

National Cheng Kung University Hospital ( Site 2205), Tainan, Not set

National Taiwan University Hospital-Oncology ( Site 2208), Taipei, Not set

Mackay Memorial Hospital-Chest Medicine ( Site 2201), Taipei, Not set

Chang Gung Medical Foundation-Linkou Branch-Clinic of Chest Medicine ( Site 2202), Taoyuan, Not set

Prapokklao Hospital ( Site 2306), Mueang, Chanthaburi

Faculty of Medicine - Khon Kaen University ( Site 2305), Muang, Khon Kaen

Faculty of Medicine Siriraj Hospital ( Site 2301), Bangkok, Krung Thep Maha Nakhon

Bangkok Metropolitan Administration Medical College and Vajira Hospital ( Site 2300), Dusit, Krung Thep Maha Nakhon

Lampang Cancer Hospital ( Site 2304), Mueang Lampang, Lampang

Songklanagarind hospital ( Site 2303), HatYai, Songkhla

Maharaj Nakorn Chiang Mai Hospital ( Site 2302), Chiang Mai, Not set

Medipol Mega Universite Hastanesi-oncology ( Site 1811), Stanbul, Istanbul

Hacettepe Universite Hastaneleri-oncology hospital ( Site 1801), Ankara, Not set

Gazi Universitesi-Oncology ( Site 1804), Ankara, Not set

Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1800), Ankara, Not set

Memorial Kayseri Hastanesi ( Site 1805), Kayseri, Not set

Mersin Sehir Eğitim ve Araştırma Hastanesi-Oncology ( Site 1808), Mersin, Not set

Samsun Medical Park Hastanesi-medical oncology ( Site 1806), Samsun, Not set

Burjeel Medical City ( Site 2600), Abu Dhabi, Abu Zaby

Torbay Hospital ( Site 1906), Torquay, Devon

St Bartholomew's Hospital ( Site 1901), London, London, City Of

City Hospital, Nottingham University Hospitals NHS Trust-NCCTT ( Site 1911), Nottingham, Nottinghamshire

Conditions: Non-small Cell Lung Cancer, NSCLC

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A Study of Daratumumab

NCT05438043

Recruiting

The purpose of this study is to provide ongoing access to study treatments for participants with multiple myeloma or smoldering multiple myeloma benefiting from treatment in certain Janssen Research and Development (R\&D) studies that use daratumumab as part of the study treatment regimen: access for all participants regardless of treatment group in daratumumab studies and access to participants in daratumumab-containing arms in the non-daratumumab studies will be allowed from studies which have... Read More

Gender:

ALL

Ages:

All

Trial Updated:

08/14/2025

Locations: University of Miami Sylvester Cancer Center, Miami, Florida +75 locations

University of Miami Sylvester Cancer Center, Miami, Florida

Emory University, Atlanta, Georgia

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Barnes-jewish Hospital, Saint Louis, Missouri

Icahn School of Medicine at Mount Sinai - The Derald H. Ruttenberg, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Baylor University Medical Center, Dallas, Texas

ZNA Stuivenberg, Antwerpen, Not set

Peking Union Medical College Hospital, Beijing, Not set

Beijing Chaoyang Hospital, Beijing, Not set

Peking University First Hospital, Beijing, Not set

Peking University People s Hospital, Beijing, Not set

The First Bethune Hospital of Jilin University, Changchun, Not set

West China Hospital Si Chuan University, Chengdu, Not set

Fujian Medical University, Fuzhou, Not set

Guangdong General Hospital, Guangzhou, Not set

Nanfang Hospital, Guangzhou, Not set

First Affiliated Hospital Medical School of Zhejiang University, Hangzhou, Not set

First affiliated Hospital of Zhejiang University, Hangzhou, Not set

Shanghai Changzheng Hospital, Shanghai, Not set

Ruijin Hospital Shanghai Jiao Tong University, Shanghai, Not set

Renji Hospital, Shanghai Jiaotong University School of Medicine, ShangHai, Not set

First Affiliated Hospital SooChow University, Suzhou, Not set

Tianjin cancer hospital, Tianjin, Not set

Institute of Hematology and Blood Diseases Hospital, Tianjin, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Henan Cancer Hospital, Zhengzhou, Not set

Aarhus University Hospital, Aarhus N, Not set

Centre Hospitalier Universitaire (CHU) de Caen, Caen, Not set

CHU Nantes, Nantes Cedex 1, Not set

Hopital Saint Louis, Paris, Not set

Hopital Haut Leveque, Pessac, Not set

Klinikum Chemnitz gGmbH, Chemnitz, Not set

Asklepios Klinik Altona, Hamburg, Not set

Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II,, Tübingen, Not set

Alexandra General Hospital of Athens, Athens Attica, Not set

Anticancer Hospital of Thessaloniki Theageneio, Thessaloniki, Not set

Universita Degli Studi di Roma Tor Vergata, Roma, Not set

Sapienza University of Rome, Roma, Not set

Pusan National University Hospital, Busan, Not set

National Cancer Center, Goyang si, Not set

Chonnam National University Hwasun Hospital, Hwasun, Not set

Seoul National University Bundang Hospital, Seongnam, Not set

Seoul National University Hospital, Seoul, Not set

Samsung Medical Center, Seoul, Not set

The Catholic University of Korea Seoul St Marys Hospital, Seoul, Not set

Wojewodzki Szpital Specjalistyczny w Legnicy, Legnica, Not set

Uniwersytecki Szpital Kliniczny w Poznaniu, Poznan, Not set

S.P. Botkin Moscow City Clinical Hospital, Moscow, Not set

Nizhniy Novgorod Region Clinical Hospital, Nizhny Novgorod, Not set

Republican Hospital named by V.A.Baranova, Petrozavodsk, Not set

Ryazan Regional Clinical Hospital, Ryazan, Not set

City Hospital No.15, Saint-Petersburg, Not set

Saratov State Medical University, Saratov, Not set

Clinical Research Institute of Hematology and Transfusiology, St-Petersburg, Not set

Oncology Dispensary of Komi Republic, Syktyvkar, Not set

Hosp. Univ. Germans Trias I Pujol, Badalona, Not set

Hosp Clinic de Barcelona, Barcelona, Not set

Inst. Cat. Doncologia-H Duran I Reynals, Hospitalet de Llobregat, Not set

Hosp. Univ. de Canarias, La Laguna, Not set

Hosp. Gral. Univ. Gregorio Maranon, Madrid, Not set

Clinica Univ. de Navarra, Madrid, Not set

Hosp. Univ. Ramon Y Cajal, Madrid, Not set

Hosp. Univ. 12 de Octubre, Madrid, Not set

Centro Integral Oncológico Clara Campal, Madrid, Not set

Hosp. Gral. Univ. J.M. Morales Meseguer, Murcia, Not set

Clinica Univ. de Navarra, Pamplona, Not set

Hosp Clinico Univ de Salamanca, Salamanca, Not set

Hosp. Univ. Dr. Peset, Valencia, Not set

Ege Universitesi Tip Fakultesi, Izmir, Not set

Communal Nonprofit Enterprise 'Cherkasy Regional Oncology Dispensary Of Cherkasy Regional Council', Cherkasy, Not set

Dnepropetrovsk City Clinical Hospital #4, Regional Hematology Center, Dnepropetrovsk, Not set

Kharkov Regional Clinical Oncology Center, Dept. of Hematology, Kharkov, Not set

Vinnytsya Regional Clinical Hospital named after M.I.Pirogov, Vinnitsa, Not set

St James University Hospital, Leeds, Not set

Royal Marsden Hospital, Surrey, Not set

Conditions: Multiple Myeloma

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