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All Clinical Trials in United Kingdom
A listing of 3097 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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DHF-20-1839-2: Clinical Performance Study Protocol for Therascreen® KRAS RGQ PCR Kit
Recruiting
To utilize the therascreen KRAS RGQ PCR Kit, as a screening test in Amgen's Phase 3 Clinical Study Protocol 20210081, in order to identify patients with mCRC KRAS G12C mutation positive tumors to be enrolled in the drug clinical trial. Results of the Phase 3 Amgen Study 20210081 will serve as the basis for establishing the clinical performance of the therascreen® KRAS RGQ PCR Kit as a companion diagnostic (CDx) for the identification of patients with metastatic colorectal cancer, who may benefit... Read More
To utilize the therascreen KRAS RGQ PCR Kit, as a screening test in Amgen's Phase 3 Clinical Study Protocol 20210081, in order to identify patients with mCRC KRAS G12C mutation positive tumors to be enrolled in the drug clinical trial. Results of the Phase 3 Amgen Study 20210081 will serve as the basis for establishing the clinical performance of the therascreen® KRAS RGQ PCR Kit as a companion diagnostic (CDx) for the identification of patients with metastatic colorectal cancer, who may benefit from treatment with sotorasib. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: QIAGEN Gaithersburg, Inc, Manchester, Not set
QIAGEN Gaithersburg, Inc, Manchester, Not set
Conditions: Metastatic Colorectal Cancer (mCRC)
Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia
Recruiting
The primary objective is to describe in the real-world setting patient characteristics and outcomes of patients with primary hypercholesterolaemia (heterozygous familial and non-familial) or mixed dyslipidaemia using bempedoic acid and/or its fixed-dose combination with ezetimibe in managing plasma levels of low-density lipoprotein cholesterol (LDL-C).
Secondary objectives are to document and evaluate as applicable:
* Assessment of the cardiovascular risk of patients treated with bempedoic aci... Read More
The primary objective is to describe in the real-world setting patient characteristics and outcomes of patients with primary hypercholesterolaemia (heterozygous familial and non-familial) or mixed dyslipidaemia using bempedoic acid and/or its fixed-dose combination with ezetimibe in managing plasma levels of low-density lipoprotein cholesterol (LDL-C).
Secondary objectives are to document and evaluate as applicable:
* Assessment of the cardiovascular risk of patients treated with bempedoic acid and/or its fixed-dose combination with ezetimibe using different risk scores (e.g. Systematic Coronary Risk Estimation (SCORE) system, SMART score for Very High Risk patients and Framingham risk score for High Risk patients. The scores will be re-calculated during the analysis and used as an analytical tool only).
* Changes in low-density lipoprotein cholesterol (LDL-C) levels prior to treatment with bempedoic acid and/or its fixed-dose combination with ezetimibe compared to 1 year follow-up and subsequent data collection points, if applicable.
* Characterize plasma levels of other potentially ASCVD-modifying cholesterol fragments, namely, LDL-C, total cholesterol (TC), apolipoprotein B (apoB), high-density lipoprotein cholesterol (HDL-C), non-HDL-C, triglycerides (TGs) and lipoprotein A (Lp\[a\]) compared to 1 year follow-up and subsequent data collection points, if applicable.
* Changes in the levels of inflammatory marker hsCRP compared to 1 year follow-up and subsequent data collection points, if applicable.
* Adverse Drug Reactions associated to bempedoic acid and/or its fixed-dose combination with ezetimibe.
* Changes in uric acid levels compared to 1 year follow-up and subsequent data collection points, if applicable.
* Relevant CV events:
* Myocardial infarction
* Unstable angina
* Coronary artery bypass graft surgery (CABG)
* Percutaneous transluminal coronary angioplasty (PTCA)
* Stroke
* Transient ischemic attack (TIA)
* Acute peripheral arterial occlusion
* All-cause death
* Cardiovascular (CV)-death
* Adverse effects associated with lipid-modifying treatment (LMT)
* Laboratory abnormalities
* Muscle-associated symptoms
* New onset and/or worsening diabetes
* Changes in the patients´ glycemic status over time
* Site characteristics (sites and practitioners) caring for patients treated with bempedoic acid and/or its fixed-dose combination with ezetimibe.
* Use of LMTs prior or concomitantly to receiving bempedoic acid and/or its fixed-dose combination with ezetimibe (therapies including combination treatments).
* Bempedoic acid and/or its fixed-dose combination with ezetimibe treatment parameters such as treatment duration by therapy, dosage, prescription intervals, permanent discontinuations, switches and reasons for these, (concomitant medication, additional therapy/interventions).
* Healthcare resource use especially consultation visits with specialist, nurse time and hospitalizations as well as patient-reported outcome using EQ-5D-5L and PAM-13. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: Dr. Armin Öhlinger Kardiologe & innere Medizin, Dornbirn, Not set +490 locations
Dr. Armin Öhlinger Kardiologe & innere Medizin, Dornbirn, Not set
Landeskrankenhaus Feldkirch, Feldkirch, Not set
Institut für Herz- und Gefäßerkrankungen GmbH, Graz, Not set
LKH-Univ. Klinikum Graz, Graz, Not set
Medizinische Universität Graz, Graz, Not set
Internist Dr. med. univ. Stefan Moser, Horsching, Not set
Medizinische Universität Innsbruck, Innsbruck, Not set
KABEG Klinikum Klagenfurt am Wörthersee, Klagenfurt am Worthersee, Not set
Konventhospital der Barmherzigen Brüder Linz, Linz, Not set
Ordination Dr. Johannes Föchterle, Linz, Not set
Ordination Frau Prof. Dr. Yvonne Winhofer-Stöckl, Mattersburg, Not set
Landesklinikum Melk, Melk, Not set
Kompetenz-Zentrum Diabetes, Salzburg, Not set
Ordination Universitätsdozent Dr. Alexander Kober, Sankt Aegyd Am Neuwalde, Not set
Ordination Dr. med. univ. Evelyn Fließer-Görzer, Sankt Stefan Ob Stainz, Not set
Landeskrankenhaus Villach, Villach, Not set
Ordination Dr. Thomas Maca, Wien, Not set
Klinik Hietzing, Wiener Gesundheitsverbund, Wien, Not set
Zentrum für Klinische Studien Dr. Hanusch GmbH, Wien, Not set
Allgemeines Krankenhaus der Stadt Wien, Wien, Not set
Univ.-Prof. Dr. Thomas Stulnig, Wien, Not set
Herz Zentrum Währing, Wien, Not set
Karl Landsteiner Institut für kardiovaskuläre und intensivmedizinische Forschung, Wien, Not set
Schnürer & Fritsch - Gruppenpraxis für Innere Medizin, Wien, Not set
ASZ, Aalst, Not set
Clinique Saint-Luc Bouge Namur, Bouge, Not set
Epicura Hornu, Boussu, Not set
A.Z. KLINA Brasschaat, Brasschaat, Not set
Clinique Saint-Jean Bruxelles, Bruxelles, Not set
CHU Brugman, Bruxelles, Not set
CUB-Hôpital Erasme, Bruxelles, Not set
UZ Brussel, Bruxelles, Not set
Clinique de l'Europe Saint Elisabeth, Bruxelles, Not set
UCL Saint-Luc Woluwé Bruxelles, Bruxelles, Not set
Private Practice, Ciney, Not set
Az Sint Blazius, Dendermonde, Not set
UZ Antwerpen, Edegem, Not set
Z.O.L - Campus St. Jan, Genk, Not set
AZ St-Lucas & Volkskliniek, Ghent, Not set
UZ Gent, Ghent, Not set
GHDC Charleroi - Site Hôpital Saint-Joseph, Gilly, Not set
Private Practice, Gribomont, Not set
Pôle hospitalier Jolimont, Haine-Saint-Paul, Not set
BVBA Med Kab, Halen, Not set
Jessa Ziekenhuis, Hasselt, Not set
CHR Huy, Huy, Not set
JAN YPERMAN Ziekenhuis, Ieper, Not set
AZ Groeninge Kortrijk, Kortrijk, Not set
CHU Tivoli, La Louvière, Not set
UZ Leuven, Leuven, Not set
CHR Citadelle de Liège, Liège, Not set
CHU Liège, Liège, Not set
CHU Charleroi Hopital civil Marie-Curie, Lodelinsart, Not set
CHU Mons Ambroise Paré, Mons, Not set
AZ Sint Jan, Oostende, Not set
AZ Delta, Roeselare, Not set
AZ Glorieux, Ronse, Not set
Sint Trudo, Sint Truiden, Not set
Sint-Andriesziekenhuis Tielt, Tielt, Not set
Private Practice, Tienen, Not set
CHU UCL Mont-Godinne, Yvoir, Not set
Downtown Clinic Aachen, Aachen, Not set
Praxis Delonge, Aachen, Not set
Praxis Osterziel, Amberg, Not set
MVZ Helios Aue, Aue, Not set
Kardiologische Praxis Enders, Bad Elster, Not set
SLK-Klinikum am Plattenwald, Bad Friedrichshall, Not set
Herzcarre Praxis, Bad Homburg, Not set
Kardiologische Praxis, Bad Homburg, Not set
Zentrum für klinische Forschung, Bad Homburg, Not set
Universitätsklinikum Freiburg - Universitäts-Herzzentrum, Bad Krozingen, Not set
Praxis am Landratspark, Bad Segeberg, Not set
Hausärzte am Spritzenhaus, Baiersbronn, Not set
CIMS Studienzentrum Bamberg GmbH Drs. Kirschner/Haas/Ritzel, Bamberg, Not set
Kardiologische Praxis, Bechhofen, Not set
Praxis Rankestraße, Berlin, Not set
SKP Studienzentrum der kardiologischen Praxisgemeinschaft Rankestrasse GmbH, Berlin, Not set
Herzpraxis Berlin MVZ, Berlin, Not set
Charité - Universitätsmedizin Berlin, Berlin, Not set
Dres. Seeger & Partner, Berlin, Not set
Diabetespraxis Dr. Braun, Berlin, Not set
Lipidambulanz Charite, Berlin, Not set
Praxiszentrum Biedenkopf, Biedenkopf, Not set
Praxis Dr. A. Biedermann, Blankenhain, Not set
MVZ für Innere Medizin, Bonn, Not set
Kardiologische Gemeinschaftspraxis Bremerhaven, Bremerhaven, Not set
Kardiologie im Friedrichspalast Bruchsal, Bruchsal, Not set
Studiengesellschaft Könemann und Steinmann GbR, Bunde, Not set
MediClin Reha-Zentrum Spreewald, Burg, Not set
Studiengesellschaft Könemann und Steinmann GbR, Bünde, Not set
MVZ am Küchwald, Chemnitz, Not set
Kardiologische Praxis Stellmach, Chemnitz, Not set
MVZ Polymed, Chemnitz, Not set
Praxis Dr. Menzel, Dessau, Not set
Klinikum Lippe GmbH, Detmold, Not set
Kardiologische Gemeinschaftspraxis, Dortmund, Not set
Cardiologicum Dresden/Pirna, Dresden, Not set
Hausärztliche Gemeinschaftspraxis mit diabetologischem Schwerpunkt, Dresden, Not set
Dres. Günther/Kolschmann, Dresden, Not set
Herzzentrum Dresden, Universitätsklinik an der Technischen Universität Dresden, Dresden, Not set
Universitätsklinikum Carl Gustav Carus, Dresden, Not set
DZDM Diabeteszentrum Duisburg Mitte, Duisburg, Not set
Nierenzentrum Düren, Düren, Not set
Universitätsklinikum Düsseldorf, Düsseldorf, Not set
Praxis Dilltal, Ehringshausen, Not set
Praxis Dipl. -Med. Petra Herrmann, Eisenach, Not set
Kardiologische Praxis, Elsterwerda, Not set
Gemeinschaftspraxis ISP Erlangen, Erlangen, Not set
Hausarztzentrum am Germaniaplatz, Essen, Not set
DIAKO Flensburg, Flensburg, Not set
Praxis für Nieren und Hochdruck-Krankheiten, Flensburg, Not set
MVZ Altstadt-Carree Fulda, Fulda, Not set
Klinikum Fulda, Fulda, Not set
Praxis Dr. Langel, Gera, Not set
Cardiocampus Gemeinschaftspraxis für Herz- und Kreislauferkrankungen, Gifhorn, Not set
Universitätsmedizin Greifswald, Greifswald, Not set
Praxis Dr. Müller, Gräfenhainichen, Not set
Praxis für Gefäßmedizin, Görlitz, Not set
Universitätsmedizin Göttingen, Göttingen, Not set
Evangelisches Krankenhaus Hagen-Haspe, Hagen, Not set
Praxis, Hainburg, Not set
Cardiologicum Hamburg - Praxis Wandsbek, Hamburg, Not set
Diabetes Zentrum Wandsbeck, Hamburg, Not set
MVZ Prof. Mathey, Prof. Schofer, Hamburg, Not set
Kardiologie am Tibarg, Hamburg, Not set
Kardiologie List, Hannover, Not set
Kardiologische Praxis, Hannover, Not set
Kardiologische Praxis, Haßloch, Not set
Kardiologische Schwerpunktpraxis, Heidelberg, Not set
Universitätsklinikum Heidelberg, Heidelberg, Not set
Praxis Heik/Wedig, Heiligenstadt, Not set
KARDIO-IN Kardiologische Gemeinschaftspraxis, Ingolstadt, Not set
Kardiologische Praxis, Kaiserslautern, Not set
SRH Klinikum Karlsbad-Langensteinbach, Karlsbad, Not set
B. Braun Ambulantes Herzzentrum Kassel, Kassel, Not set
Praxis Dr. Heiner Müller, Katzhütte, Not set
Nephrologie Kiel, Kiel, Not set
Gemeinschaftsklinikum Mittelrhein, Koblenz, Not set
Studienzentrum der Inneren Medizin I & II am Klinikum Konstanz, Konstanz, Not set
Kardiologie Dr. med. E. Persicke / Dr. med. O. Scheuermann, Kornwestheim, Not set
Kardiologische Praxis Kyritz, Kyritz, Not set
Uniklinik Köln, Köln, Not set
Zentrum für klinische Forschung, Köln, Not set
IKAPP, Köln, Not set
Universitätsklinikum Leipzig, Leipzig, Not set
Kardiologische Praxis Boudriot, Leipzig, Not set
MVZ Stoffwechselmedizin Leipzig, Leipzig, Not set
Praxis Dr. I.Simon-Wagner, Lichtenfels, Not set
St. Vincenz Krankenhaus, Limburg, Not set
Gemeinschaftspraxis Dr. Jens Biesenbaum und Dr. Uwe Gerbaulet, Lohne, Not set
Cardio Centrum Ludwigsburg-Bietigheim, Ludwigsburg, Not set
Kardiologische Praxisklinik Ludwigshafen, Ludwigshafen, Not set
Universität zu Lübeck, Luebeck, Not set
Kardiologische Praxis Tamm/Hoh, Lutherstadt Wittenberg, Not set
Institut für Präventive Medizin & Klinische Forschung GbR, Magdeburg, Not set
Cardiopraxis Mainz, Mainz, Not set
Katholisches Klinikum Mainz, Mainz, Not set
Universitätsklinikum Mainz, Mainz, Not set
ZE:RO Praxen, Mannheim, Not set
UMM Mannheim, Mannheim, Not set
Kardiologische Praxis, Markkleeberg, Not set
Praxis Ben-Chur, Meiningen, Not set
Praxis Haj-Yehia, Moers, Not set
Gemeinschaftspraxis Dr. Prohaska/Dr. Schulte, Mühldorf, Not set
Kardiologie Mühldorf am Inn, Mühldorf, Not set
Herzquartier Mülheim, Mülheim an der Ruhr, Not set
Kardiologie Neuhausen-Nymphenburg, München, Not set
Dres. Wauer/Windstetter, München, Not set
Praxis Kiepenkerl, Münster, Not set
Zentrum für Kardiologie an der Raphaelsklinik Münster, Münster, Not set
Praxis für Innere Medizin Münster, Münster, Not set
Universitätsklinikum Münster, Münster, Not set
Internistische Praxisgemeinschaft, Neu Isenburg, Not set
Kardiologische Praxis Northeim, Northeim, Not set
Hausarztpraxis, Oer-Erkenschwick, Not set
St. Vincenz-Krankenhaus GmbH, Paderborn, Not set
Kardiologische Praxis Papenburg - Site 6071, Papenburg, Not set
Kardiologische Praxis Papenburg - Site 6072, Papenburg, Not set
Gemeinschaftspraxis Dres. med. Karl-Heinz Göttl - Omar Adjan, Passau, Not set
Hausärztlich-Kardiologisches MVZ "Am Felsenkeller" GmbH, Pirna, Not set
Kinikum Ernst von Bergmann, Potsdam, Not set
VieSante Herzmedizin Potsdam, Potsdam, Not set
Kardiologische Gemeinschaftspraxis, Potsdam, Not set
Allgemeinmedizinisch Internistische Praxis Dr. H. Borgmann, Radebeul, Not set
Internistisch hausärtzliche Gemeinschaftspraxis Dr. Hildebrandt & Dr. Mutscher, Radebeul, Not set
Gemeinschaftspraxis Herz Riesa, Riesa, Not set
Universitätsmedizin Rostock, Rostock, Not set
MVZ Schwerin West GmbH, Schwerin, Not set
Facharztpraxis für Kardiologie und Innere Medizin, Schwäbisch Hall, Not set
Nierenzentrum Altmark, Seehausen, Not set
Zentrum für Prävention und Rehabilitation, Siegen, Not set
Klinik Singen, Singen, Not set
MEDINOS Klinik Sonneberg, Sonneberg, Not set
Kardiologische Praxis im Steiner Thor, Straubing, Not set
Praxis Dr Knöbel u. Partner, Straubing, Not set
Praxis Dr. Michael Rother, Strausberg, Not set
Diabetologische Schwerpunktpraxis, Trier, Not set
Krankenhaus der Barmherzigen Brüder Trier, Trier, Not set
Studienzentrum der Herzklinik Ulm GbR, Ulm, Not set
Praxis Dr. Hansen, Unterwellenborn, Not set
Praxis Dr. Dengler/Hohenstatt, Ursensollen, Not set
Herzzentrum Saar, Völklingen, Not set
GRN Weinheim, Weinheim, Not set
Kardiologische Praxis Al-Zoebi, Wermsdorf, Not set
Internistische Gemeinschaftspraxis Dr. med. Schreckenberg, Dr. med. Vorderstraße, Weyhe, Not set
Forschungszentrum-Ruhr / KliFoCenter GmbH, Witten, Not set
Kardiologische Fachpraxis, Wolmirstedt, Not set
Zentrum für Nieren- und Hochdrucklerkrankungen Hofaue, Wuppertal, Not set
Universitätsklinikum Würzburg, Würzburg, Not set
Gemeinschaftspraxis am Angerbrunnen, Zwiesel, Not set
Ospedale Generale Regionale "F. Miulli", Acquaviva Delle Fonti, Not set
P.O. Agrigento Ospedale San Giovanni di Dio, Agrigento, Not set
IRCCS-INRCA Ancona, Ancona, Not set
Ospedale di Anzio, Anzio, Not set
Ospedale dei Castelli, Ariccia, Not set
Ospedale "C. e G. Mazzoni", Ascoli Piceno, Not set
A.O. San Giuseppe Moscati, Avellino, Not set
Ospedale SS Nicola e Filippo, Avezzano, Not set
Ospedale S. Paolo, Bari, Not set
A.O.U. Consorziale - Policlinico Bari, Bari, Not set
Azienda Universitaria Ospedaliera Consorziale - Policlinico di Bari - Site 08016, Bari, Not set
Azienda Universitaria Ospedaliera Consorziale - Policlinico di Bari - Site 08017, Bari, Not set
Azienda Ospedaliera S. Pio presidio G. Rummo, Benevento, Not set
AUSL Bologna Ospedale di Bentivoglio, Bentivoglio, Not set
ASST Papa Giovanni XXIII, Bergamo, Not set
Ospedale Maggiore Carlo Alberto Pizzardi, Bologna, Not set
Policlinico Sant'Orsola Bologna-Malpighi, Bologna, Not set
Ospedale di Bolzano - Site 08070, Bolzano, Not set
Ospedale di Bolzano - Site 08112, Bolzano, Not set
Spedali Civili di Brescia, Brescia, Not set
Ospedale Santo Spirito Casale Monferrato, Casale Monferrato, Not set
A.O. S. Anna e S. Sebastiano, Caserta, Not set
ULLS 2 MARCA TREVIGIANA Ospedale di Castelfranco Veneto, Castelfranco Veneto, Not set
AOU Policlinico Vittorio Emanuele Presidio Ospedaliero Gaspare Rodolico, Catania, Not set
Azienda Ospedaliera Cannizzaro, Catania, Not set
L'Azienda Ospedaliero-Universitaria "Renato Dulbecco" di Catanzaro, Catanzaro, Not set
Ospedale Civile Santa Maria Incoronata dell'Olmo, Cava Dè Tirreni, Not set
Policlinico SS. Annunziata, Chieti, Not set
ASL TO4 Presidio Riunito di Ciriè-Lanzo, Ciriè, Not set
Azienda Ospedaliero-Universitaria di Ferrara "Arcispedale Sant'Anna", Cona, Not set
Ospedale San Salvatore, Coppito, Not set
Ospedale Santa Maria Nuova, Firenze, Not set
AOU Careggi - Site 08067, Firenze, Not set
AOU Careggi - Site 08081, Firenze, Not set
AOU Careggi - Site 08090, Firenze, Not set
Azienda Ospedaliera Universitaria "Ospedali Riuniti" di Foggia, Foggia, Not set
Ospedale Policlinico San Martino, Genova, Not set
Presidio Ospedaliero S.O. Padre Antero Micone, Genova, Not set
Ospedale della Misericordia, Grosseto, Not set
Ospedale Sant'Andrea, La Spezia, Not set
ASP Catanzaro Presidio Ospedaliero "Giovanni Paolo II", Lamezia Terme, Not set
Ospedale Vito Fazzi, Lecce, Not set
Ospedale Mater Salutis, Legnago, Not set
Presidio Ospedaliero "Madonna delle Grazie", Matera, Not set
Presidio ospedaliero San Giovanni di Dio, Melfi, Not set
A.O.U. Policlinico "G. Martino", Messina, Not set
ULSS 3 SERENISSIMA Ospedale dell'Angelo, Mestre, Not set
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Site 08039, Milano, Not set
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Site 08097, Milano, Not set
Centro Cardiologico Monzino, Milano, Not set
Ospedale San Luca - Gruppo Istituto Auxologico Italiano, Milano, Not set
IRCCS Ospedale Galeazzi-Sant'Ambrogio, Milano, Not set
ASST Grande Ospedale Metropolitano Niguarda, Milano, Not set
Ospedale Niguarda, Milano, Not set
ULSS 3 Serenissima Presidio Ospedaliero di Mirano, Mirano, Not set
AOU Modena Policlinico Modena, Modena, Not set
A.O.R.N. Antonio Cardarelli, Napoli, Not set
A.O.R.N. MONALDI OSPEDALE DEI COLLI Ospedale Monaldi, Napoli, Not set
A.O.U. Federico Ii, Napoli, Not set
Azienda Ospedaliera Specialistica dei Colli Ospedale Monaldi, Napoli, Not set
Policlinico Università Federico II - Napoli, Napoli, Not set
Ospedale Umberto I, Nocera Inferiore, Not set
AOU Maggiore della Carità di Novara, Novara, Not set
Ospedale San Giacomo, Novi Ligure, Not set
Azienda ospedaliera-Università di Padova, Padova, Not set
A.O.U. Policlinico "P. Giaccone", Palermo, Not set
Casa di Cura Triolo Zancla Hospital, Palermo, Not set
ICS Maugeri, Pavia, Not set
USL Umbria I, Perugia, Not set
Azienda Ospedaliera S. Maria della Misericordia di Perugia, Perugia, Not set
Ospedale Guglielmo da Saliceto, Piacenza, Not set
Fondazione Monasterio, Pisa, Not set
P. O. Portogruaro, Portogruaro, Not set
Azienda Ospedaliera Regionale San Carlo di Potenza, Potenza, Not set
Nuovo Ospedale Santo Stefano, Prato, Not set
Azienda Sanitaria Provinciale di Ragusa Ospedale Giovanni Paolo II, Ragusa, Not set
Ospedale Santa Maria delle Croci, Ravenna, Not set
ASST Rhodense - Ospedale di Circolo di Rho, Rho, Not set
Ospedale San Camillo De Lellis, Rieti, Not set
Ospedale Infermi AUSL Romagna, Rimini, Not set
Ospedale degli Infermi di Rivoli, Rivoli, Not set
Policlinico Tor Vergata, Roma, Not set
Ospedale Sandro Pertini, Roma, Not set
Policlinico Umberto I, Roma, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Site 08046, Roma, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Site 08121, Roma, Not set
Policlinico Casilino, Roma, Not set
AOU S. Andrea, Roma, Not set
A.O. San Giovanni di Dio e Ruggi D'Aragona, Salerno, Not set
ASST Valle Olona P.O. Saronno, Saronno, Not set
Ospedale S. Bartolomeo, Sarzana, Not set
AOU Sassari Ospedale SS. Annunziata, Sassari, Not set
IRCCS Multimedica, Sesto San Giovanni, Not set
A.O.U. Senese Ospedale Santa Maria alle Scotte, Siena, Not set
AOU Senese- Policlinico Le Scotte, Siena, Not set
Casa di cura Villa Verde, Taranto, Not set
Azienda Ospedaliera Santa Maria, Terni, Not set
Ospedale Mauriziano Presidio Umberto I, Torino, Not set
AOU Ospedali Riuniti di Ancona, Torrette, Not set
Ospedale Santa Chiara, Trento, Not set
ULLS 2 MARCA TREVIGIANA Ospedale Ca' Foncello, Treviso, Not set
Ospedale di Cattinara, Trieste, Not set
Ospedale Santa Maria della Misericordia, Udine, Not set
Ospedale Santa Maria della Misericordia, Urbino, Not set
ASST Settelaghi Ospedale di Circolo e Fondazione Macchi, Varese, Not set
Ospedale Castelli Verbania, Verbania, Not set
ZGT, Almelo, Not set
Meander Mc, Amersfoort, Not set
AUMC, Amsterdam, Not set
Mc Leeuwarden, Amsterdam, Not set
Rijnstate, Arnhem, Not set
AMPHIA, Breda, Not set
Albert Schweitzer, Dordrecht, Not set
ZGV, Ede, Not set
Maxima Medisch Centrum, Eindhoven, Not set
GHZ, Gouda, Not set
Spaarne Gasthuis, Haarlem, Not set
Saxenburgh Medisch Centrum, Hardenberg, Not set
Tergooi Mc, Hilversum, Not set
Treant Bethesda Hoogeveen, Hoogeveen, Not set
Dijklander, Hoorn, Not set
BOVEN IJ, Leeuwarden, Not set
ALRIJNE, Leiderdorp, Not set
MUMC+, Maastricht, Not set
Erasmus Mc, Rotterdam, Not set
Franciscus Gasthuis, Rotterdam, Not set
MAASSTAD, Rotterdam, Not set
SKB, Tiel, Not set
ZRT, Winterswijk, Not set
Isala Zwolle, Zwolle, Not set
Hospital Abente y Lago, A Coruña, Not set
Hospital General de Albacete, Albacete, Not set
Hospital Virgen de los Lirios, Alcoi, Not set
Hospital Universitario Fundación Alcorcón, Alcorcón, Not set
Hospital General Universitario Dr. Balmis, Alicante, Not set
Hospital Universitario Torrecárdenas, Almeria, Not set
Hospital Universitario Central de Asturias, Asturias, Not set
Clínica Mapfre Salud Gijón, Asturias, Not set
Hospital Universitario San Agustin, Asturias, Not set
Hospital Vital Álvarez-Buylla, Asturias, Not set
Hospital Vall d'Hebron, Bacelona, Not set
Hospital Universitario Nuestra Señora del Perpetuo Socorro, Badajoz, Not set
Hospital Germans Trias i Pujol, Badalona, Barcelona, Not set
Hospital Universitario de Cruces, Barakaldo, Not set
Hospital del Mar, Barcelona, Not set
Hospital de Sant Pau, Barcelona, Not set
Hospital Clínic de Barcelona, Barcelona, Not set
Hospital Clínico de Barcelona, Barcelona, Not set
Hospital de Bellvitge, Barcelona, Not set
Hospital Universitario de Basurto, Bilbao, Not set
Hospital Universitario de Burgos, Burgos, Not set
Hospital General Universitario de Castellón, Castellón de la Plana, Not set
Hospital Universitario Reina Sofía, Cordoba, Not set
Hospital del Henares, Coslada, Madrid, Not set
Hospital Universitario San Pedro de Alcántara, Cáceres, Not set
Hospital Universitario Puerta del Mar, Cádiz, Not set
Hospital de Denia, Denia, Not set
Hospital UNiversitario de Donostia, Donostia, Not set
Hospital de Fuenlabrada, Fuenlabrada Madrid, Not set
Hospital Universitario de Cabueñes, Gijon, Not set
Hospital Universitario Virgen de las Nieves, Granada, Not set
Hospital Universitario San Cecilio, Granada, Not set
Hospital Universitario Juan Ramón Jiménez, Huelva, Not set
Hospital Universitario Médico-Quirúrgico de Jaén, Jaén, Not set
Hospital Jerez de la Frontera, Jerez De La Frontera, Cádiz, Not set
Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Not set
Hospital San Rafael, La Coruña, Not set
Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Not set
Complejo Hospitalario Universitario Insular Materno-Infantil de Gran Canaria, Las Palmas de Gran Canaria, Not set
Hospital Universitario de León, León, Not set
HOSPITAL UNIVERSITARi ARNAU DE VILANOVA, Lleida, Not set
Hospital San Pedro, Logroño, Not set
Hospital Universitario Lucus Augusti, Lugo, Not set
Hospital Universitario la Princesa, Madrid, Not set
Hospital Universitario Gregorio Marañón, Madrid, Not set
Hospital Ruber Internacional, Madrid, Not set
Hospital Universitario Ramón y Cajal, Madrid, Not set
Hospital Clínico San Carlos, Madrid, Not set
Hospital Clínico Universitario San Carlos, Madrid, Not set
Hospital Universitario Fundación Jiménez Díaz, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Hospital Central de la Defensa Gómez-Ulla, Madrid, Not set
Hospital HM Montepríncipe, Madrid, Not set
Hospital Universitario de Torrejón, Madrid, Not set
Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda Madrid, Not set
Hospital Universitario Puerta de Hierro Majadahonda, Majdahonda Madrid, Not set
Consulta de Cardiología Dr. Javier Mora Robles, Malaga, Not set
Hospital Costa del Sol, Marbella Málaga, Not set
Hospital de Mendaro, Mendaro, Not set
Hospital General Universitario Reina Sofía, Murcia, Not set
Hospital Clínico Universitario Virgen Arrixaca, Murcia, Not set
Hospital Regional Universitario de Málaga, Málaga, Not set
Hospital Universitario Virgen de La Victoria, Málaga, Not set
Hospital Universitario Son LLatzer, Palma de Mallorca, Not set
Hospital Universitario de Navarra, Pamplona, Not set
Hospital de Sagunto, Port De Sagunt, Not set
Hospital Universitari Sant Joan, Reus, Not set
Corporación Sanitaria Parc Taulí, Sabadell, Barcelona, Not set
Hospital Universitario de Salamanca, Salamanca, Not set
Hospital Santa Caterina, Salt, Girona, Not set
Complexe hospitalari Moisès Broggi, Sant Joan Despi, Barcelona, Not set
Hospital Universitario Marqués de Valdecilla, Santander, Not set
Hospital Clinico Universitario Santiago de Compostela, Santiago de Compostela, Not set
Hospital Universitario Virgen del Rocio, Sevilla, Not set
Hospital de Valme, Sevilla, Not set
Hospital Universitario Vírgen del Rocío, Sevilla, Not set
Complejo Asistencial Universitario de Soria, Soria, Not set
Hospital de Sant Pau i Santa Tecla, Tarragona, Not set
Hospital Universitari de Tarragona Joan XXIII, Tarragona, Not set
Hospital Universitario Mútua de Terrassa, Terrassa Barcelona, Not set
Hospital General Universitario de Toledo, Toledo, Not set
Hospital Clínico Universitario de Valencia, Valencia, Not set
Hospital Arnau de Vilanova, Valencia, Not set
Vithas Valencia 9 de Octubre, Valencia, Not set
Consorcio Hospital General Universitario de Valencia, Valencia, Not set
Hospital Universitari i Politècnic La Fe, Valencia, Not set
Hospital Universitario Rio Hortega, Valladolid, Not set
Hospital Álvaro Cunqueiro, Vigo Pontevedra, Not set
Hospital de La Plana, Villarreal, Castellón, Not set
Hospital Clinico Universitaro Lozano Blesa, Zaragoza, Not set
Diabetologie & Endokrinologie Baden, Baden, Not set
University Hospital Basel, Basel, Not set
Inselspital, Universitätsspital Bern, Bern, Not set
Praxis Dr. med Urs Beat Gröflin, Binningen, Not set
Hochgebirgsklinik Davos, Davos, Not set
Schlossberg Ärztezentrum Frauenfeld, Frauenfeld, Not set
Hôpitaux Universitaires de Genève, Genève, Not set
Spital Lachen AG, Lachen, Not set
Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Not set
University of Lausanne, Lausanne, Not set
Kantonsspital Baselland, Liestal, Not set
EOC Ente Ospedaliero Cantonale, Lugano, Not set
MIP Associazione Medico in Pratica c/o Studio Medico Cardiologico Acquistapace, Lugano, Not set
Praxis Prof. Dr. med. Gottfried Rudofsky, Olten, Not set
HÔPITAL RIVIERA-CHABLAIS, VAUD-VALAIS, Centre hospitalier de Rennaz, Rennaz, Not set
Kantonsspital St.Gallen, St.Gallen, Not set
Spital Thun, Thun, Not set
Prof. Dr. med. Stephane Bosquet, Yverdon-les-Bains, Not set
Diagnostisches und Therapeutisches Herzzentrum, Zürich, Not set
Universitätsspital Zürich, Zürich, Not set
Royal United Hospitals Bath NHS Foundation Trust, Bath, Not set
South Eastern Ulster Hospital, Belfast, Not set
University Hospital of Wales, Cardiff, Not set
Rowden Surgery, Chippenham, Not set
Craigavon Area Hospital, Craigavon, Not set
Darlington Memorial Hospital, Darlington, Not set
Carmel Medical Practice, Darlington, Not set
Dartford and Gravesham NHS Trust Darent Valley Hospital, Dartford, Not set
University Hospital North Durham, Durham, Not set
Southend University Hospital, Essex, Not set
Oaks Healthcare, Hampshire, Not set
West Morland General Hospital, Kendal, Not set
North Blaby PCN, Leicester, Not set
Lincoln County Hospital, Lincoln, Not set
Barts Health NHS Trust/ QMUL, London, Not set
Freuchen Medical Centre, London, Not set
Royal Free Hospital Lipid Clinic, London, Not set
Hammersmith Hospital, London, Not set
Imperial College London, London, Not set
Manchester Royal Infirmary, Manchester, Not set
Manchester University NHS Foundation Trust, Manchester, Not set
Manchester University NHS Foundation Trust, Manchester, Not set
Wythenshawe Hospital, Manchester, Not set
STRIVE, The James Cook University Hospital, Middlesbrough, Not set
North Tees Hospital, Northumbria, Not set
City Hospital, Nottingham, Not set
Derriford Hospital Lipid Clinic, Plymouth, Not set
Queen Alexandra Hospital, Portsmouth, Not set
Whiston Hospital, Prescot, Not set
North Manchester General Hospital, Salford, Not set
Moorgreen Hospital, Southampton, Not set
Queen's Hospital Lipid Clinic, Staffordshire, Not set
Princess Royal Hospital, Telford, Not set
Torbay and South Devon NHS Foundation Trust, Torquay, Not set
Trowbridge Health Centre, Trowbridge, Not set
Royal Cornwall Hospital, Truro, Not set
North Wales Cardiac Centre, Wales, Not set
Wansford and Kings Cliffe Practice, Wansford, Not set
Bridgewater Surgeries, Watford, Not set
Sheepcot Medical Centre, Watford, Not set
Conditions: Hypercholesterolemia, Mixed Dyslipidemia
Virtual Reality in Elective Caesarean Births Study (VREC)
Recruiting
This study will establish the safety of a known intervention in a novel setting. It will assess how maternal anxiety during the peri-operative period of an elective cesarean section (eCS) is affected by the introduction of a virtual reality (VR) tool. A cesarean section is the most common operation performed in the world. Indeed, locally, we perform approximately 450 eCS annually, equating to 10% of all births. High maternal anxiety in the peri-operative period is well recognised. Although anxie... Read More
This study will establish the safety of a known intervention in a novel setting. It will assess how maternal anxiety during the peri-operative period of an elective cesarean section (eCS) is affected by the introduction of a virtual reality (VR) tool. A cesarean section is the most common operation performed in the world. Indeed, locally, we perform approximately 450 eCS annually, equating to 10% of all births. High maternal anxiety in the peri-operative period is well recognised. Although anxiety is considered to be an emotional response it has many physiological consequences which can confer significant morbidity. These include an increased pain perception (with higher analgesic requirement), increased length of hospital stay and a higher risk of infection. Providing high-quality pre-operative information to help patients reduce their anxiety has been used in other medical fields. The use of VR to deliver this information to paediatric populations has been shown to be particularly effective. VR has had limited scope outside of this population and we wish to change this.
Women booked for an eCS at the Royal United Hospital (RUH) will be eligible to participate. A bespoke VR tool (a video of a woman's journey through the process of an elective section at the RUH) will be shown to one group of women prior to eCS whilst another group will receive the standard preoperative information.
A series of quantitative and qualitative data points will be collected across both groups assessing their anxiety and satisfaction with the birthing process throughout the peri-operative period. The two groups will then be compared.
Recruitment will occur prior to the birth during scheduled appointments with the Midwifery team. If proven to be a safe intervention, we hope to run a larger study aiming to determine the efficacy and role of VR in improving maternal outcomes in cesarean births. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: Bath Birthing Centre, Royal United Hospital Bath Foundation Trust, Bath, Not set
Bath Birthing Centre, Royal United Hospital Bath Foundation Trust, Bath, Not set
Conditions: Anxiety, Pregnancy, Pain
Combination Study of Guadecitabine/ASTX727 and Pembrolizumab
Recruiting
HyPeR is a multi-centre Phase 1 Dose Escalation Study of Guadecitabine (SGI-110)/ASTX727 a Second Generation Hypo-Methylating Agent in Combination with Pembrolizumab (MK3475) in Patients with Refractory Solid Tumours. The investigators will be investigating the safety and toxicity of the combination.
HyPeR is a multi-centre Phase 1 Dose Escalation Study of Guadecitabine (SGI-110)/ASTX727 a Second Generation Hypo-Methylating Agent in Combination with Pembrolizumab (MK3475) in Patients with Refractory Solid Tumours. The investigators will be investigating the safety and toxicity of the combination. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: Royal Marsden Hospital, Sutton, Surrey +1 locations
Royal Marsden Hospital, Sutton, Surrey
UCLH, London, Not set
Conditions: Non Small Cell Lung Cancer
Clinical Evaluation of a Paediatric Sleep Diagnosis Technology
Recruiting
The objective of this project is to gather research data and subsequently evaluate algorithms to demonstrate clinical efficacy of a novel sleep apnoea detection system in the paediatric population.
The Study will involve patients who will have been referred for diagnosis of sleep apnoea, and the ultimate aim will be to compare the output of a novel apnoea detection system against in -clinic polysomnography.
The objective of this project is to gather research data and subsequently evaluate algorithms to demonstrate clinical efficacy of a novel sleep apnoea detection system in the paediatric population.
The Study will involve patients who will have been referred for diagnosis of sleep apnoea, and the ultimate aim will be to compare the output of a novel apnoea detection system against in -clinic polysomnography. Read Less
Gender:
ALL
Ages:
Between 1 year and 18 years
Trial Updated:
08/12/2025
Locations: Sheffield Children Hospital, Sheffield, Not set +1 locations
Sheffield Children Hospital, Sheffield, Not set
Southampton Children's Hospital, Southampton, Not set
Conditions: Sleep Apnea
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Recruiting
This Phase III, multicenter, double-blind, placebo-controlled treat-through study will evaluate the efficacy and safety of induction and maintenance therapy with Afimkibart (also known as RO7790121) in participants with moderately to severely active Crohn's disease (CD).
This Phase III, multicenter, double-blind, placebo-controlled treat-through study will evaluate the efficacy and safety of induction and maintenance therapy with Afimkibart (also known as RO7790121) in participants with moderately to severely active Crohn's disease (CD). Read Less
Gender:
ALL
Ages:
Between 16 years and 80 years
Trial Updated:
08/12/2025
Locations: Digestive Health Specialists of the Southeast (Gastroenterology Associates of Dothan) - Dothan, Dothan, Alabama +180 locations
Digestive Health Specialists of the Southeast (Gastroenterology Associates of Dothan) - Dothan, Dothan, Alabama
Arizona Digestive Health, P.C (ADH), Sun City, Arizona
Valley View Internal Medicine, Garden Grove, California
310 Clinical Research, Inglewood, California
Gastro Care Associates, Lancaster, California
Om Research LLC, Lancaster, California
United Gastroenterologists, Los Alamitos, California
Acclaim Clinical Research, Inc., San Diego, California
UCSF/Medical Center at Mount Zion, San Francisco, California
Rocky Mountain Gastroenterology, Littleton, Colorado
Peak Gastroenterology Surgery Center, Lone Tree, Colorado
Access Research Institute, Brooksville, Florida
Gastro Florida, Clearwater, Florida
HealthMed Clinical Center Inc., Coral Gables, Florida
Hi Tech and Global Research, LLC, Coral Gables, Florida
The Sister Life Research, Hialeah, Florida
NeoClinical Research, Hialeah, Florida
Clinical Research of Osceola, LLC, Kissimmee, Florida
Florida Research Institute - Lakewood, Lakewood Ranch, Florida
LCC Medical Research Institute, LLC, Miami, Florida
Ambert Medical Research, Miami, Florida
Orlando Regional Healthcare, Orlando, Florida
Nodal Medical Center Research - NMC, Tampa, Florida
University of South Florida School of Medicine Morsani Center for Advanced Health Care, Tampa, Florida
Guardian Angel Research Center, LLC, Tampa, Florida
Theia Clinical Research Centers, LLC, Temple Terrace, Florida
Digestive Healthcare of Georgia, Atlanta, Georgia
Atlanta Gastroenterology Associates, Atlanta, Georgia
Gastroenterology Associates of Central Georgia, Macon, Georgia
Grand Teton Research Group, PLLC, Idaho Falls, Idaho
Illinois Gastroenterology Group-Glenview powered by GI Alliance, Glenview, Illinois
GI Alliance - Gurnee, Gurnee, Illinois
Gastroenterology Health Partners, PLLC, New Albany, Indiana
Kansas Gastroenterology, LLC under Clinical Trials Network, Wichita, Kansas
Tri-State Gastroenterology Associates, Crestview Hills, Kentucky
Gastroenterology Health Partners, PLLC, Louisville, Kentucky
Brigham and Women's Hospital, Boston, Massachusetts
Michigan Center of Medical Research, Farmington Hills, Michigan
Gastroenterology Associates and Endoscopy Center of North Mississippi, Oxford, Mississippi
Delta Gastroenterology & Endoscopy Center, Southaven, Mississippi
Las Vegas Clinical Trials, LLC, North Las Vegas, Nevada
Lenox Hill Hospital, New York, New York
DiGiovanna Inst for Med Ed&Res, North Massapequa, New York
Queens Village Medical Care, Queens Village, New York
Gastroenterology Group of Rochester under CTNx, Rochester, New York
Omega Research North Carolina, LLC, Fuquay-Varina, North Carolina
Monroe Biomedical Research, Monroe, North Carolina
Dayton Gastroenterology, Inc., Beavercreek, Ohio
Ohio Gastroenterology Group, Columbus, Ohio
The Ohio State University Wexner Medical Center, Columbus, Ohio
Gastro Intestinal Research Institute of Northern Ohio, Westlake, Ohio
Central Sooner Research, Norman, Oklahoma
Frontier Clinical Re search, LLC, Uniontown, Pennsylvania
University Gastroenterology, Providence, Rhode Island
Gastroenterology Associates, PA PA of Greenville, Greenville, South Carolina
Gastro One, Germantown, Tennessee
Quality Medical Research, Nashville, Tennessee
Texas Clinical Research Institute, LLC, Arlington, Texas
Proactive El Paso,LLC, El Paso, Texas
Amel Med LLC, Georgetown, Texas
Cano Medical Center, Harlingen, Texas
TDDC dba GI Alliance Research, Mansfield, Texas
SMS Clinical Research, LLC, Mesquite, Texas
Gastroenterology Research of America, LLC, San Antonio, Texas
GI Alliance - Southlake, Southlake, Texas
Tyler Research Institute, LLC, Tyler, Texas
Tidewater Gastroenterology Pllc T/A Gastro. Assoc. of Tidewater, Chesapeake, Virginia
Emeritas Research Group, Lansdowne Town Center, Virginia
Gastroenterology Consultants and Endoscopy Center of Southwest Virginia, Roanoke, Virginia
Tidewater Physicians Multispecialty Group (TPMG) - Clinical Research Division - Williamsburg, Williamsburg, Virginia
The Vancouver Clinic, Vancouver, Washington
Hospital Britanico, Ciudad Autonoma Bs As, Not set
Royal Prince Alfred Hospital, Sydney, New South Wales
Mater Misericordiae Limited, South Brisbane, Queensland
Barmherzige Brüder Wien, Wien, Not set
Medizinische Universität Wien, Wien, Not set
AZORG Campus Aalst-Moorselbaan, Aalst, Not set
Cliniques Universitaires St-Luc, Bruxelles, Not set
UZ Antwerpen, Edegem, Not set
AZ Maria Middelares, Gent, Not set
AZ Sint Lucas (Sint Lucas), Gent, Not set
Jessa Zkh (Campus Virga Jesse), Hasselt, Not set
CHC MontLégia, Liege, Not set
CHU de Liège (Sart Tilman), Liège, Not set
CHU HELORA - Hôpital de Mons - Site Kennedy, Mons, Not set
Vitaz, Sint Niklaas, Not set
Hospital de Clinicas de Porto Alegre X, Porto Alegre, Rio Grande Do Sul
CPQuali Pesquisa Clinica Ltda, Sao Paulo, São Paulo
South Edmonton Gastroenterology, Edmonton, Alberta
C.I.C. Mauricie, Trois-rivieres, Quebec
Hospital Guillermo Grant Benavente, Concepcion, Not set
Medwal, Santiago, Not set
Clinica Universidad de Los Andes, Santiago, Not set
Peking University Third Hospital, Beijing, Not set
the First Hospital of Jilin University, Changchun, Not set
Third Xiangya Hospital Centrel South University, Changsha, Not set
West China Hospital of Sichuan University, Chengdu City, Not set
Chongqing General Hospital, Chongqing City, Not set
The First Affiliated Hospital Of Fujian Medical University, Fuzhou City, Not set
The second Affiliated Hospital of Guangzhou Medical University, Guangzhou City, Not set
The sixth affiliated hospital of Sun Yat-Sen University, Guangzhou City, Not set
Zhejiang Province Traditional Chinese Medical Hospital, Hangzhou City, Not set
Sir Run Run Shaw Hospital Zhejiang University, Hangzhou City, Not set
Anhui Provincial Hospital, Hefei, Not set
The First Affiliated Hospital of Anhui Medical University, Hefei, Not set
Huizhou Central People's Hospital, Huizhou, Not set
The 1st Affiliated Hospital of Nanchang Unversity, Nanchang City, Not set
The First Affiliate Hospital of Guangxi Medical University, Nanning, Not set
The First Affiliated Hospital of Ningbo University, Ningbo City, Not set
Shanghai East Hospital, Shanghai City, Not set
Peking University Shenzhen Hospital, Shenzhen, Not set
Taizhou Hospital Of Zhejiang Province, Taizhou City, Not set
The Central Hospital of Wuhan, Wuhan City, Not set
Ren Min Hospital Affiliated Wu Han University, Wuhan, Not set
Wuxi People's Hospital, Wuxi, Not set
Zhongshan Hospital Xiamen University, Xiamen, Not set
The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set
Zhuzhou Central Hospital, Zhuzhou, Not set
SurGal Clinic s.r.o., Brno, Not set
Gastroenterologie s.r.o., Hradec Kralove, Not set
Fakultni nemocnice Hradec Kralove, Hradec Kralove, Not set
Herlev Hospital, Herlev, Not set
CEMDOE (Centro Médico de Diabetes, Obesidad y Especialidades), Santo Domingo, Not set
CHU Amiens - Hopital Sud, Amiens, Not set
Hopital Nord, Marseille, Not set
CHU Nice - Hopital de l'Archet 2, Nice, Not set
CHU Bordeaux - Hôpital Haut-Lévêque, Pessac, Not set
Hopital Robert Debre, Reims, Not set
CHU de Rennes - Hopital de Pontchaillo, Rennes, Not set
CHU Saint Etienne - Hôpital Nord, Saint Etienne, Not set
Charite - Campus Benjamin Franklin, Berlin, Not set
AGAPLESION Markus-Krankenhaus, Frankfurt, Not set
Klinik Johann Wolfgang von Goethe Uni, Frankfurt, Not set
Universitaetsklinikum Halle (Saale), Halle, Not set
Universitaetsklinikum Jena, Jena, Not set
Klinikum Mannheim GmbH Universitätsklinikum, Mannheim, Not set
Universitätsklinikum Ulm, Ulm, Not set
Obudai Egeszsegugyi Centrum Kft., Budapest, Not set
Semmelweis Egyetem, Budapest, Not set
Pannonia Maganorvosi Centrum, Budapest, Not set
Clinexpert Gyongyos Kft, Gyongyos, Not set
Clinfan Szolgaltato Kft., Szekszard, Not set
Fejer Varmegyei Szent György Egyetemi Oktatokorhaz, Székesfehérvár, Not set
Chaim Sheba Medical Center, Ramat Gan, Not set
Ospedale Isola Tiberina Gemelli, Roma, Lazio
ASST Rhodense - Ospedale di Rho, Rho, Lombardia
Ospedale Mauriziano Umberto I, Torino, Piemonte
Gamagori City Hospital, Aichi, Not set
Tsujinaka Hospital Kashiwanoha, Chiba, Not set
Kinshukai Infusion Clinic, Osaka, Not set
Matsuda Hospital, Shizuoka, Not set
Boca Clinical Trials Mexico S.C. (Guadalajara), Guadalajara, Jalisco
Medical Care & Research SA de CV, Mérida, Yucatan
Universitair Medisch Centrum Utrecht, Utrecht, Not set
Centrum Medyczne "Medis", Bydgoszcz, Not set
Centrum Medyczne Lukamed Joanna Luka-Wendrowska, Chojnice, Not set
Endo-Med Sp. z o.o., Karczew, Not set
Allmedica Badania Kliniczne Sp z o.o. Sp K., Nowy Targ, Not set
SOLUMED Centrum Medyczne, Pozna?, Not set
Gastromed Sp. z o.o., Toru?, Not set
WIP Warsaw IBD Point Profesor Kierkus, Warszawa, Not set
Centralny Szpital Kliniczny MSW w Warszawie, Warszawa, Not set
Przychodnia EuroMediCare, Wroc?aw, Not set
Melita Medical, Wroc?aw, Not set
Vistamed & Vertigo Spó?Ka Z Ograniczon? Odpowiedzialno?Ci?, Wroc?aw, Not set
ETG Zamosc, Zamosc, Not set
Hospital de Braga, Braga, Not set
Hospital de Santa Maria, Lisboa, Not set
Hospital de Sao Joao, Porto, Not set
Klinical Investigations Group LLC, San Juan, Not set
Hospital Universitario Marques de Valdecilla, Santander, Cantabria
Hospital Universitario La Paz, Madrid, Not set
Hospital Universitario Reina Sofía, Murcia, Not set
China Medical University Hospital, Taichung City, Not set
Division of Gastroenterology, Depart of Medicine, Fac of Med., Chulalongkorn University, Bangkok, Not set
Division of Gastroenterology, Depart of Internal Med, Siriraj H, Mahidol Uni, Bangkok, Not set
Khon Kaen Uni, Khon Kaen, Not set
Division of Gastroenterology, Depart of Medicine, Fac. of Med, Songklanagarind University, Songkhla, Not set
Royal Liverpool University Hospital, Liverpool, Not set
King College Hospital NHS Foundation Trust, London, Not set
Queen Anne Street Medical Centre, London, Not set
Conditions: Moderately to Severely Active Crohns Disease
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Recruiting
Participants include men and women ≥ 40 years of age with T2DM, established CV disease, a history of HTN with an SBP of at least 130 mmHg at screening, who meet the predefined serum potassium level, and with at least one additional risk factor for HF.
The study will include an optional pre-screening period to facilitate sites' identification of potentially eligible participants to enter the full screening assessments. Participants will not be required to visit the site and no informed consent i... Read More
Participants include men and women ≥ 40 years of age with T2DM, established CV disease, a history of HTN with an SBP of at least 130 mmHg at screening, who meet the predefined serum potassium level, and with at least one additional risk factor for HF.
The study will include an optional pre-screening period to facilitate sites' identification of potentially eligible participants to enter the full screening assessments. Participants will not be required to visit the site and no informed consent is required for the optional pre-screening period. The pre-screening assessments do not replace the full screening tests at Visit 1.
Upon entering the screening period, all consented participants (after signature of screening ICF) will be screened during an up to 14-day screening period. Participants who meet all screening inclusion/exclusion criteria but are not treated with SGLT2i or are treated for less than 4 weeks will enter a run-in period with dapagliflozin 10 mg once daily for at least 4 weeks (and not more than 6 weeks) before randomisation.
Site visits will take place at approximately 2-, 4-, 8-, 16-, and 34-weeks following randomisation. Thereafter visits will occur approximately every 4 months.
The study closure procedures will be initiated when the predetermined number of the first secondary endpoint events (ie, the composite of hospitalisation for HF or CV death) is predicted to have occurred i.e., the PACD.
In case of premature discontinuation of the blinded study intervention, participants will remain in the study. Unless a participant meets the dapagliflozin specific discontinuation criteria, they will continue to receive open label dapagliflozin 10 mg. It is important that the scheduled study visits and data collection continue according to the study protocol. Read Less
Gender:
ALL
Ages:
40 years and above
Trial Updated:
08/11/2025
Locations: Research Site, Birmingham, Alabama +862 locations
Research Site, Birmingham, Alabama
Research Site, Centreville, Alabama
Research Site, Fairhope, Alabama
Research Site, Huntsville, Alabama
Research Site, Mobile, Alabama
Research Site, Vestavia Hills, Alabama
Research Site, Gilbert, Arizona
Research Site, Glendale, Arizona
Research Site, Dublin, California
Research Site, Huntington Beach, California
Research Site, Inglewood, California
Research Site, La Jolla, California
Research Site, Lakewood, California
Research Site, Lincoln, California
Research Site, Loma Linda, California
Research Site, San Diego, California
Research Site, San Dimas, California
Research Site, San Francisco, California
Research Site, San Francisco, California
Research Site, Thousand Oaks, California
Research Site, Aurora, Colorado
Research Site, Englewood, Colorado
Research Site, Stamford, Connecticut
Research Site, Waterbury, Connecticut
Research Site, Crystal River, Florida
Research Site, Fort Lauderdale, Florida
Research Site, Fort Myers, Florida
Research Site, Gainesville, Florida
Research Site, Hialeah, Florida
Research Site, Jacksonville, Florida
Research Site, Lakeland, Florida
Research Site, Miami, Florida
Research Site, Miami, Florida
Research Site, Miami, Florida
Research Site, Palmetto Bay, Florida
Research Site, Saint Augustine, Florida
Research Site, Albany, Georgia
Research Site, Atlanta, Georgia
Research Site, Canton, Georgia
Research Site, Columbus, Georgia
Research Site, Suwanee, Georgia
Research Site, Woodstock, Georgia
Research Site, Chicago, Illinois
Research Site, Chicago, Illinois
Research Site, Island Lake, Illinois
Research Site, Park Ridge, Illinois
Research Site, Indianapolis, Indiana
Research Site, Munster, Indiana
Research Site, Richmond, Indiana
Research Site, South Bend, Indiana
Research Site, El Dorado, Kansas
Research Site, Lenexa, Kansas
Research Site, Newton, Kansas
Research Site, Wichita, Kansas
Research Site, Lexington, Kentucky
Research Site, Paducah, Kentucky
Research Site, Shreveport, Louisiana
Research Site, Baltimore, Maryland
Research Site, Beltsville, Maryland
Research Site, Nottingham, Maryland
Research Site, Potomac, Maryland
Research Site, Boston, Massachusetts
Research Site, New Bedford, Massachusetts
Research Site, Roslindale, Massachusetts
Research Site, Troy, Michigan
Research Site, Mankato, Minnesota
Research Site, Minneapolis, Minnesota
Research Site, Columbia, Missouri
Research Site, Kansas City, Missouri
Research Site, Saint Louis, Missouri
Research Site, Missoula, Montana
Research Site, Norfolk, Nebraska
Research Site, Omaha, Nebraska
Research Site, Carson City, Nevada
Research Site, Portsmouth, New Hampshire
Research Site, Somerset, New Jersey
Research Site, Albuquerque, New Mexico
Research Site, Albuquerque, New Mexico
Research Site, Albany, New York
Research Site, Brooklyn, New York
Research Site, Brooklyn, New York
Research Site, Massapequa, New York
Research Site, New York, New York
Research Site, Queens Village, New York
Research Site, Charlotte, North Carolina
Research Site, Durham, North Carolina
Research Site, Kernersville, North Carolina
Research Site, Monroe, North Carolina
Research Site, Morehead City, North Carolina
Research Site, New Bern, North Carolina
Research Site, Raleigh, North Carolina
Research Site, Rocky Mount, North Carolina
Research Site, Beavercreek, Ohio
Research Site, Cincinnati, Ohio
Research Site, Cincinnati, Ohio
Research Site, Columbus, Ohio
Research Site, Maumee, Ohio
Research Site, Norman, Oklahoma
Research Site, Oklahoma City, Oklahoma
Research Site, Grants Pass, Oregon
Research Site, Medford, Oregon
Research Site, Camp Hill, Pennsylvania
Research Site, Horsham, Pennsylvania
Research Site, Scottdale, Pennsylvania
Research Site, Smithfield, Pennsylvania
Research Site, Fort Mill, South Carolina
Research Site, Greenville, South Carolina
Research Site, Mount Pleasant, South Carolina
Research Site, North Charleston, South Carolina
Research Site, Morristown, Tennessee
Research Site, Nashville, Tennessee
Research Site, Abilene, Texas
Research Site, Austin, Texas
Research Site, Beaumont, Texas
Research Site, Dallas, Texas
Research Site, El Paso, Texas
Research Site, Mesquite, Texas
Research Site, Paris, Texas
Research Site, Pearland, Texas
Research Site, San Antonio, Texas
Research Site, Stephenville, Texas
Research Site, Sugar Land, Texas
Research Site, Woodway, Texas
Research Site, Roy, Utah
Research Site, Burke, Virginia
Research Site, Charlottesville, Virginia
Research Site, Falls Church, Virginia
Research Site, Richmond, Virginia
Research Site, Salem, Virginia
Research Site, Kingwood, West Virginia
Research Site, Morgantown, West Virginia
Research Site, Buenos Aires, Not set
Research Site, Caba, Not set
Research Site, Caba, Not set
Research Site, Caba, Not set
Research Site, Caba, Not set
Research Site, Ciudad de Buenos Aires, Not set
Research Site, Cordoba, Not set
Research Site, Córdoba, Not set
Research Site, La Plata, Not set
Research Site, Mar del Plata, Not set
Research Site, Mar del Plata, Not set
Research Site, Rosario, Not set
Research Site, Rosario, Not set
Research Site, San Nicolas de los Arroyos, Not set
Research Site, San Nicolás, Not set
Research Site, San Vicente, Not set
Research Site, Santa Fe, Not set
Research Site, Adelaide, Not set
Research Site, Elizabeth Vale, Not set
Research Site, Fremantle, Not set
Research Site, Geelong, Not set
Research Site, Kingswood, Not set
Research Site, Leabrook, Not set
Research Site, Maroubra, Not set
Research Site, Merewether, Not set
Research Site, Milton, Not set
Research Site, Mulgrave, Not set
Research Site, Osborne Park, Not set
Research Site, Rockhampton, Not set
Research Site, Wollongong, Not set
Research Site, Belem, Not set
Research Site, Blumenau, Not set
Research Site, Bragança Paulista, Not set
Research Site, Brasília, Not set
Research Site, Campina Grande do Sul, Not set
Research Site, Campinas, Not set
Research Site, Campinas, Not set
Research Site, Curitiba, Not set
Research Site, Curitiba, Not set
Research Site, Juiz de Fora, Not set
Research Site, Natal, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Porto Alegre, Not set
Research Site, Rio de Janeiro, Not set
Research Site, Sao Jose dos Campos, Not set
Research Site, Sao Paulo, Not set
Research Site, São José do Rio Preto, Not set
Research Site, São Paulo, Not set
Research Site, São Paulo, Not set
Research Site, São Paulo, Not set
Research Site, Tatuí, Not set
Research Site, Haskovo, Not set
Research Site, Panagyurishte, Not set
Research Site, Petrich, Not set
Research Site, Pleven, Not set
Research Site, Pleven, Not set
Research Site, Plovdiv, Not set
Research Site, Russe, Not set
Research Site, Shumen, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Stara Zagora, Not set
Research Site, Varna, Not set
Research Site, Calgary, Alberta
Research Site, Calgary, Alberta
Research Site, Sherwood Park, Alberta
Research Site, Surrey, British Columbia
Research Site, Moncton, New Brunswick
Research Site, St. John, New Brunswick
Research Site, St. John's, Newfoundland and Labrador
Research Site, Halifax, Nova Scotia
Research Site, Sydney, Nova Scotia
Research Site, Cambridge, Ontario
Research Site, Guelph, Ontario
Research Site, Hamilton, Ontario
Research Site, Hamilton, Ontario
Research Site, Markham, Ontario
Research Site, Newmarket, Ontario
Research Site, North York, Ontario
Research Site, North York, Ontario
Research Site, Oakville, Ontario
Research Site, Ottawa, Ontario
Research Site, Sarnia, Ontario
Research Site, Toronto, Ontario
Research Site, Toronto, Ontario
Research Site, Toronto, Ontario
Research Site, Laval, Quebec
Research Site, Levis, Quebec
Research Site, Mirabel, Quebec
Research Site, Montreal, Quebec
Research Site, Montreal, Quebec
Research Site, Saint-Charles-Borromee, Quebec
Research Site, Sherbrooke, Quebec
Research Site, Terrebonne, Quebec
Research Site, Trois-Rivières, Quebec
Research Site, Regina, Saskatchewan
Research Site, Quebec, Not set
Research Site, Quebec, Not set
Research Site, Baotou, Not set
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Changchun, Not set
Research Site, Changchun, Not set
Research Site, Changde, Not set
Research Site, Changsha, Not set
Research Site, Changsha, Not set
Research Site, Changzhou, Not set
Research Site, Chengdu, Not set
Research Site, Chengdu, Not set
Research Site, Chifeng, Not set
Research Site, Chongqing, Not set
Research Site, Chongqing, Not set
Research Site, Guangzhou, Not set
Research Site, Guangzhou, Not set
Research Site, Harbin, Not set
Research Site, Hefei, Not set
Research Site, Hengyang, Not set
Research Site, Heze, Not set
Research Site, Huangshi, Not set
Research Site, Huizhou, Not set
Research Site, Jinan, Not set
Research Site, Jining, Not set
Research Site, Kaifeng, Not set
Research Site, Liaocheng, Not set
Research Site, Linhai, Not set
Research Site, Linyi, Not set
Research Site, Lishui, Not set
Research Site, Luoyang, Not set
Research Site, Luoyang, Not set
Research Site, Meihekou, Not set
Research Site, Nanchang, Not set
Research Site, Nanjing, Not set
Research Site, Nantong, Not set
Research Site, Nanyang, Not set
Research Site, Panjin, Not set
Research Site, Pingxiang, Not set
Research Site, Sanya, Not set
Research Site, Shanghai, Not set
Research Site, Shanghai, Not set
Research Site, Shenyang, Not set
Research Site, Siping, Not set
Research Site, Suzhou, Not set
Research Site, Suzhou, Not set
Research Site, Taiyuan, Not set
Research Site, Taiyuan, Not set
Research Site, Tianjin, Not set
Research Site, Wenzhou, Not set
Research Site, Wuhan, Not set
Research Site, Wuhan, Not set
Research Site, Xi'an, Not set
Research Site, Xianyang, Not set
Research Site, Xuzhou, Not set
Research Site, Yinchuan, Not set
Research Site, Zhumadian, Not set
Research Site, Zigong, Not set
Research Site, Benesov, Not set
Research Site, Brandys nad Labem, Not set
Research Site, Brno, Not set
Research Site, Brno, Not set
Research Site, Broumov, Not set
Research Site, Chlumec nad Cidlinou, Not set
Research Site, Hodonin, Not set
Research Site, Humpolec, Not set
Research Site, Jílové u Prahy, Not set
Research Site, Krnov, Not set
Research Site, Olomouc, Not set
Research Site, Ostrava, Not set
Research Site, Plzeň, Not set
Research Site, Police nad Metují, Not set
Research Site, Prague, Not set
Research Site, Praha 10, Not set
Research Site, Praha 4, Not set
Research Site, Praha, Not set
Research Site, Praha, Not set
Research Site, Praha, Not set
Research Site, Aalborg, Not set
Research Site, Aarhus N, Not set
Research Site, Aarhus, Not set
Research Site, Esbjerg, Not set
Research Site, Frederiksberg, Not set
Research Site, Gistrup, Not set
Research Site, Herlev, Not set
Research Site, Herning, Not set
Research Site, Hillerød, Not set
Research Site, Hjørring, Not set
Research Site, Holbæk, Not set
Research Site, Hvidovre, Not set
Research Site, København, Not set
Research Site, Roskilde, Not set
Research Site, Slagelse, Not set
Research Site, Svendborg, Not set
Research Site, Viborg, Not set
Research Site, Amiens, Not set
Research Site, Angers, Not set
Research Site, Aurillac Cedex, Not set
Research Site, Besançon Cedex, Not set
Research Site, Bobigny, Not set
Research Site, Bois-Guillaume, Not set
Research Site, Brest Cedex, Not set
Research Site, Caen, Not set
Research Site, Cholet, Not set
Research Site, Clermont-Ferrand, Not set
Research Site, Colombes, Not set
Research Site, Corbeil Essonnes Cedex, Not set
Research Site, Dijon, Not set
Research Site, Dijon, Not set
Research Site, La Roche Sur Yon Cedex 9, Not set
Research Site, La Rochelle, Not set
Research Site, Le Coudray, Not set
Research Site, Le Creusot, Not set
Research Site, Lyon, Not set
Research Site, Marseille, Not set
Research Site, Montpellier Cedex 5, Not set
Research Site, Nantes Cedex 1, Not set
Research Site, Narbonne CEDEX, Not set
Research Site, PARIS Cedex 15, Not set
Research Site, Paris, Not set
Research Site, Paris, Not set
Research Site, Pierre Benite, Not set
Research Site, Toulouse, Not set
Research Site, Vandoeuvre les Nancy Cedex, Not set
Research Site, Villeurbanne, Not set
Research Site, Aachen, Not set
Research Site, Amberg, Not set
Research Site, Bad Homburg, Not set
Research Site, Bad Oeynhausen, Not set
Research Site, Bamberg, Not set
Research Site, Bechhofen, Not set
Research Site, Berlin, Not set
Research Site, Berlin, Not set
Research Site, Berlin, Not set
Research Site, Berlin, Not set
Research Site, Berlin, Not set
Research Site, Berlin, Not set
Research Site, Bochum, Not set
Research Site, Bochum, Not set
Research Site, Bremen, Not set
Research Site, Deggingen, Not set
Research Site, Dresden, Not set
Research Site, Elsterwerda, Not set
Research Site, Essen, Not set
Research Site, Essen, Not set
Research Site, Essen, Not set
Research Site, Essen, Not set
Research Site, Frankfurt, Not set
Research Site, Freiburg, Not set
Research Site, Friedrichsthal, Not set
Research Site, Fulda, Not set
Research Site, Gelnhausen, Not set
Research Site, Görlitz, Not set
Research Site, Hamburg, Not set
Research Site, Hamburg, Not set
Research Site, Hamburg, Not set
Research Site, Haßloch, Not set
Research Site, Heidelberg, Not set
Research Site, Homburg, Not set
Research Site, Kaiserslautern, Not set
Research Site, Kassel, Not set
Research Site, Köln, Not set
Research Site, Köln, Not set
Research Site, Langen, Not set
Research Site, Leipzig, Not set
Research Site, Leipzig, Not set
Research Site, Leipzig, Not set
Research Site, Ludwigshafen, Not set
Research Site, Ludwigshafen, Not set
Research Site, Mannheim, Not set
Research Site, Markkleeberg, Not set
Research Site, Munich, Not set
Research Site, Münster, Not set
Research Site, Naunhof, Not set
Research Site, Neuruppin, Not set
Research Site, Nittendorf, Not set
Research Site, Obertshausen, Not set
Research Site, Oldenburg, Not set
Research Site, Osnabrück, Not set
Research Site, Papenburg, Not set
Research Site, Pirna, Not set
Research Site, Potsdam, Not set
Research Site, Reinfeld (Holstein), Not set
Research Site, Völklingen, Not set
Research Site, Wallerfing, Not set
Research Site, Wangen, Not set
Research Site, Weinheim, Not set
Research Site, Zwenkau, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Chania, Not set
Research Site, Ioannina, Not set
Research Site, Larissa, Not set
Research Site, Larissa, Not set
Research Site, Piraeus, Not set
Research Site, Piraeus, Not set
Research Site, Thessaloniki, Not set
Research Site, Thessaloniki, Not set
Research Site, Thessaloniki, Not set
Research Site, Thessaloniki, Not set
Research Site, Balatonfüred, Not set
Research Site, Balatonfüred, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Budapest, Not set
Research Site, Békéscsaba, Not set
Research Site, Debrecen, Not set
Research Site, Gyöngyös, Not set
Research Site, Kalocsa, Not set
Research Site, Nyíregyháza-Sóstóhegy, Not set
Research Site, Nyíregyháza, Not set
Research Site, Nyíregyháza, Not set
Research Site, Nyíregyháza, Not set
Research Site, Orosháza, Not set
Research Site, Pécs, Not set
Research Site, Pécs, Not set
Research Site, Szeged, Not set
Research Site, Szeged, Not set
Research Site, Szigetvár, Not set
Research Site, Szolnok, Not set
Research Site, Székesfehérvár, Not set
Research Site, Ahmedabad, Not set
Research Site, Ajmer, Not set
Research Site, Bangalore, Not set
Research Site, Belagavi, Not set
Research Site, Delhi, Not set
Research Site, Gurgaon, Not set
Research Site, Hyderabad, Not set
Research Site, Hyderabad, Not set
Research Site, Hyderabad, Not set
Research Site, Karamsad, Not set
Research Site, Kolkata, Not set
Research Site, Kolkata, Not set
Research Site, Lucknow, Not set
Research Site, Nagpur, Not set
Research Site, New Delhi, Not set
Research Site, New Delhi, Not set
Research Site, New Delhi, Not set
Research Site, Surat, Not set
Research Site, Surat, Not set
Research Site, Vijayawada, Not set
Research Site, Be'er Ya'akov, Not set
Research Site, Beer Sheba, Not set
Research Site, Beer Sheba, Not set
Research Site, Haifa, Not set
Research Site, Herzelia, Not set
Research Site, Holon, Not set
Research Site, Jerusalem, Not set
Research Site, Petah-Tikva, Not set
Research Site, Ramat Gan, Not set
Research Site, Tel Aviv, Not set
Research Site, Tel-Aviv, Not set
Research Site, Tel-Aviv, Not set
Research Site, Alessandria, Not set
Research Site, Bari, Not set
Research Site, Bergamo, Not set
Research Site, Brescia, Not set
Research Site, Chiavari, Not set
Research Site, Cona, Not set
Research Site, Foggia, Not set
Research Site, Milano, Not set
Research Site, Milano, Not set
Research Site, Milano, Not set
Research Site, Milano, Not set
Research Site, Milano, Not set
Research Site, Mondovi, Not set
Research Site, Monza, Not set
Research Site, Napoli, Not set
Research Site, Novara, Not set
Research Site, Orbassano, Not set
Research Site, Palermo, Not set
Research Site, Pavia, Not set
Research Site, Potenza, Not set
Research Site, Roma, Not set
Research Site, Roma, Not set
Research Site, Rome, Not set
Research Site, Rozzano, Not set
Research Site, Siena, Not set
Research Site, Torino, Not set
Research Site, Udine, Not set
Research Site, Aizu Wakamatsu-shi, Not set
Research Site, Amagasaki-shi, Not set
Research Site, Asahikawa-shi, Not set
Research Site, Azumino-shi, Not set
Research Site, Hakusan-shi, Not set
Research Site, Himeji, Not set
Research Site, Itabashi-ku, Not set
Research Site, Itabashi, Not set
Research Site, Izumo-shi, Not set
Research Site, Kakegawa-shi, Not set
Research Site, Kamakura-shi, Not set
Research Site, Kanazawa-shi, Not set
Research Site, Kawaguchi-shi, Not set
Research Site, Kishiwada-shi, Not set
Research Site, Kita-ku, Not set
Research Site, Kyoto-shi, Not set
Research Site, Kyoto-shi, Not set
Research Site, Matsudo-shi, Not set
Research Site, Meguro-ku, Not set
Research Site, Mito-shi, Not set
Research Site, Miyazaki-shi, Not set
Research Site, Nagano, Not set
Research Site, Ogaki-shi, Not set
Research Site, Oita-shi, Not set
Research Site, Osaka-shi, Not set
Research Site, Osaka-shi, Not set
Research Site, Osaka-shi, Not set
Research Site, Osaka, Not set
Research Site, Saitama-shi, Not set
Research Site, Sendai-shi, Not set
Research Site, Sendai-shi, Not set
Research Site, Shizuoka-shi, Not set
Research Site, Suita-shi, Not set
Research Site, Takamatsu-shi, Not set
Research Site, Takatsuki-shi, Not set
Research Site, Toyota-Shi, Not set
Research Site, Tsuchiura-shi, Not set
Research Site, Ueda-shi, Not set
Research Site, Uwajima-shi, Not set
Research Site, Yanagawa-shi, Not set
Research Site, Yokkaichi-shi, Not set
Research Site, Yokohama-shi, Not set
Research Site, Bucheon-si, Not set
Research Site, Cheongju-si, Not set
Research Site, Daegu, Not set
Research Site, Seongnam-si, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Suwon-si, Not set
Research Site, Wonju-si, Not set
Research Site, Yangsan-si, Not set
Research Site, Alor Setar, Not set
Research Site, Johor Bahru, Not set
Research Site, Kota Samarahan, Not set
Research Site, Kuala Terengganu, Not set
Research Site, Kuantan, Not set
Research Site, Kuching, Not set
Research Site, Malacca, Not set
Research Site, Rawang, Not set
Research Site, Sarawak Miri, Not set
Research Site, Seri Manjung, Not set
Research Site, Sungai Buloh, Not set
Research Site, Acapulco, Not set
Research Site, Aguascalientes, Not set
Research Site, Ciudad de México, Not set
Research Site, Cuauhtemoc, Not set
Research Site, Cuernavaca, Not set
Research Site, Culiacan, Not set
Research Site, Culiacán, Not set
Research Site, Durango, Not set
Research Site, Guadalajara, Not set
Research Site, Monterey, Not set
Research Site, San Juan del Rio, Not set
Research Site, Santiago de Querétaro, Not set
Research Site, Veracruz, Not set
Research Site, Xalapa, Not set
Research Site, Xalapa, Not set
Research Site, Zapopan, Not set
Research Site, Almelo, Not set
Research Site, Amsterdam, Not set
Research Site, Amsterdam, Not set
Research Site, Beek, Not set
Research Site, Den Bosch, Not set
Research Site, Deventer, Not set
Research Site, Ede, Not set
Research Site, Enschede, Not set
Research Site, Groningen, Not set
Research Site, Haarlem, Not set
Research Site, Harderwijk, Not set
Research Site, Hoogeveen, Not set
Research Site, Nijmegen, Not set
Research Site, Roosendaal, Not set
Research Site, Rotterdam, Not set
Research Site, Rotterdam, Not set
Research Site, Venlo, Not set
Research Site, Zwolle, Not set
Research Site, Bellavista, Not set
Research Site, Chorrillos, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, LIma, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Lima, Not set
Research Site, Piura, Not set
Research Site, Angeles City, Not set
Research Site, Cebu, Not set
Research Site, Davao City, Not set
Research Site, Davao City, Not set
Research Site, Fuente Osmena Cebu City, Not set
Research Site, Iloilo City, Not set
Research Site, Las Pinas, Not set
Research Site, Lipa City, Not set
Research Site, Manadaluyong City, Not set
Research Site, Puerto Princesa City, Not set
Research Site, Quezon City, Not set
Research Site, Roxas City, Not set
Research Site, Biała Podlaska, Not set
Research Site, Białystok, Not set
Research Site, Bydgoszcz, Not set
Research Site, Chojnice, Not set
Research Site, Chojnice, Not set
Research Site, Chrzanów, Not set
Research Site, Częstochowa, Not set
Research Site, Gdańsk, Not set
Research Site, Gdańsk, Not set
Research Site, Gdynia, Not set
Research Site, Gdynia, Not set
Research Site, Jasło, Not set
Research Site, Katowice, Not set
Research Site, Katowice, Not set
Research Site, Katowice, Not set
Research Site, Katowice, Not set
Research Site, Katowice, Not set
Research Site, Katowice, Not set
Research Site, Kraków, Not set
Research Site, Kraków, Not set
Research Site, Lublin, Not set
Research Site, Lublin, Not set
Research Site, Lublin, Not set
Research Site, Lublin, Not set
Research Site, Myszków, Not set
Research Site, Olsztyn, Not set
Research Site, Ostrów Mazowiecka, Not set
Research Site, Piekary Śląskie, Not set
Research Site, Poznań, Not set
Research Site, Poznań, Not set
Research Site, Poznań, Not set
Research Site, Poznań, Not set
Research Site, Przemyśl, Not set
Research Site, Płock, Not set
Research Site, Radzionków, Not set
Research Site, Rzeszów, Not set
Research Site, Skórzewo, Not set
Research Site, Szczecin, Not set
Research Site, Szczecin, Not set
Research Site, Tarnów, Not set
Research Site, Toruń, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Wrocław, Not set
Research Site, Zabrze, Not set
Research Site, Łódź, Not set
Research Site, Łódź, Not set
Research Site, Bacau, Not set
Research Site, Baia Mare, Not set
Research Site, Baia Mare, Not set
Research Site, Brasov, Not set
Research Site, Bucharest, Not set
Research Site, Bucuresti, Not set
Research Site, Bucuresti, Not set
Research Site, Bucuresti, Not set
Research Site, Bucuresti, Not set
Research Site, Bucuresti, Not set
Research Site, Craiova, Not set
Research Site, Iasi, Not set
Research Site, Ploiesti, Not set
Research Site, Satu Mare, Not set
Research Site, Targu Mures, Not set
Research Site, Bratislava, Not set
Research Site, Bratislava, Not set
Research Site, Bratislava, Not set
Research Site, Brezno, Not set
Research Site, Kosice, Not set
Research Site, Košice, Not set
Research Site, Lucenec, Not set
Research Site, Lucenec, Not set
Research Site, Malacky, Not set
Research Site, Namestovo, Not set
Research Site, Prievidza, Not set
Research Site, Rimavska Sobota, Not set
Research Site, Roznava, Not set
Research Site, Sabinov, Not set
Research Site, Svidník, Not set
Research Site, Ľubochňa, Not set
Research Site, Benoni, Not set
Research Site, Brackenfell, Not set
Research Site, Cape Town, Not set
Research Site, Cape Town, Not set
Research Site, Centurion, Not set
Research Site, Diepkloof, Soweto, Not set
Research Site, Durban, Not set
Research Site, Durban, Not set
Research Site, East London, Not set
Research Site, Lenasia, Not set
Research Site, Midrand, Not set
Research Site, Paarl, Not set
Research Site, Parow, Not set
Research Site, Pretoria, Not set
Research Site, Pretoria, Not set
Research Site, Somerset West, Not set
Research Site, Umkomaas, Not set
Research Site, Worcester, Not set
Research Site, A Coruña, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Cordoba, Not set
Research Site, Córdoba, Not set
Research Site, L' Hospitalet De Llobregat, Not set
Research Site, Madrid, Not set
Research Site, Málaga, Not set
Research Site, Sant Joan Despi, Not set
Research Site, Santiago(A Coruña), Not set
Research Site, Sevilla, Not set
Research Site, Sevilla, Not set
Research Site, Valencia, Not set
Research Site, Vigo, Not set
Research Site, Göteborg, Not set
Research Site, Helsingborg, Not set
Research Site, Huddinge, Not set
Research Site, Lund, Not set
Research Site, Lund, Not set
Research Site, Mölndal, Not set
Research Site, Norrköping, Not set
Research Site, Stockholm, Not set
Research Site, Stockholm, Not set
Research Site, Stockholm, Not set
Research Site, Uppsala, Not set
Research Site, Uppsala, Not set
Research Site, Changhua, Not set
Research Site, Hsinchu, Not set
Research Site, Hualien City, Not set
Research Site, Kaohsiung, Not set
Research Site, New Taipei, Not set
Research Site, Taichung City, Not set
Research Site, Taichung, Not set
Research Site, Taichung, Not set
Research Site, Taichung, Not set
Research Site, Tainan, Not set
Research Site, Taipei City, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Taoyuan, Not set
Research Site, Bangkok, Not set
Research Site, Bangkok, Not set
Research Site, Banphaeo, Not set
Research Site, Bansuan, Muang, Chonburi, Not set
Research Site, Chiang Mai, Not set
Research Site, Dusit, Not set
Research Site, Hat Yai, Not set
Research Site, Khlong Luang, Not set
Research Site, Khon Kaen, Not set
Research Site, Muang, Not set
Research Site, Naimuang, Not set
Research Site, Ubonratchathani, Not set
Research Site, Adana, Not set
Research Site, Afyonkarahisar, Not set
Research Site, Ankara, Not set
Research Site, Antalya, Not set
Research Site, Eskisehir, Not set
Research Site, Istanbul, Not set
Research Site, İstanbul, Not set
Research Site, Izmir, Not set
Research Site, Kahramanmaras, Not set
Research Site, Kocaeli, Not set
Research Site, Kütahya, Not set
Research Site, Malatya, Not set
Research Site, Samsun, Not set
Research Site, Sivas, Not set
Research Site, Chernivtsі, Not set
Research Site, Ivano-Frankivsk, Not set
Research Site, Kyiv, Not set
Research Site, Kyiv, Not set
Research Site, Kyiv, Not set
Research Site, Kyiv, Not set
Research Site, Kyiv, Not set
Research Site, Kyiv, Not set
Research Site, Ternopil, Not set
Research Site, Ternopil, Not set
Research Site, Uzhhorod, Not set
Research Site, Vinnytsia, Not set
Research Site, Vinnytsia, Not set
Research Site, Zhytomyr, Not set
Research Site, Aberdeen, Not set
Research Site, Chesterfield, Not set
Research Site, Dundee, Not set
Research Site, Gatley, Not set
Research Site, Glasgow, Not set
Research Site, Glasgow, Not set
Research Site, London, Not set
Research Site, Norwich, Not set
Research Site, Penzance, Not set
Research Site, Redruth, Not set
Research Site, Sandbach, Not set
Research Site, Southampton, Not set
Research Site, Stockton-on-Tees, Not set
Research Site, Swansea, Not set
Research Site, Weston-Super-Mare, Not set
Research Site, Wolverhampton, Not set
Research Site, Woodbridge, Not set
Research Site, Yate, Not set
Research Site, Ha Noi, Not set
Research Site, Hai Phong, Not set
Research Site, Hanoi, Not set
Research Site, Hcmc, Not set
Research Site, Ho Chi Minh City, Not set
Research Site, Ho Chi Minh, Not set
Research Site, Ho Chi Minh, Not set
Research Site, Hue, Not set
Research Site, Vinh Yen, Not set
Conditions: Heart Failure
Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS
Recruiting
The objective of this study is to compile real-world outcomes of Boston Scientific commercially approved radiofrequency (RF) ablation systems used in the central nervous system (CNS) for use in functional neurosurgery.
The objective of this study is to compile real-world outcomes of Boston Scientific commercially approved radiofrequency (RF) ablation systems used in the central nervous system (CNS) for use in functional neurosurgery. Read Less
Gender:
ALL
Ages:
All
Trial Updated:
08/11/2025
Locations: Uniklinik Köln, Cologne, Not set +2 locations
Uniklinik Köln, Cologne, Not set
Universitaetsklinikum Dusseldorf, Dusseldorf, Not set
St. Georges Hospital, London, Not set
Conditions: Parkinson Disease, Dystonia, Essential Tremor, Movement Disorders
A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)
Recruiting
This study is to assess the effectiveness and safety of pacritinib in patients with VEXAS (i.e., Vacuoles in myeloid progenitors, E1 ubiquitin-activating enzyme, X-linked, autoinflammatory manifestations, and somatic) syndrome. 78 patients will be enrolled, randomized to either pacritinib dose A, pacritinib dose B + placebo, or placebo. Randomization will be stratified by prescribed GC dose on the day of randomization.
This study is to assess the effectiveness and safety of pacritinib in patients with VEXAS (i.e., Vacuoles in myeloid progenitors, E1 ubiquitin-activating enzyme, X-linked, autoinflammatory manifestations, and somatic) syndrome. 78 patients will be enrolled, randomized to either pacritinib dose A, pacritinib dose B + placebo, or placebo. Randomization will be stratified by prescribed GC dose on the day of randomization. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/11/2025
Locations: Mayo Clinic - Scottsdale, Scottsdale, Arizona +39 locations
Mayo Clinic - Scottsdale, Scottsdale, Arizona
University of Maryland Medical Center Midtown Campus, Baltimore, Maryland
Dana Farber Cancer Institute, Boston, Massachusetts
Mayo Clinic - Rochester, Rochester, Minnesota
NYU Langone Health, New York, New York
Cleveland Clinic - Cleveland, Cleveland, Ohio
The James Cancer Hospital and Solove Research Institute, Columbus, Ohio
UT MD Anderson Cancer Center, Houston, Texas
University of Utah Healthcare, Salt Lake City, Utah
Fred Hutchinson Cancer Center, Seattle, Washington
Vancouver Coastal Health Research Institute, Vancouver, British Columbia
Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia
Princess Margaret Cancer Centre, Toronto, Ontario
Hospital du Sacre-Coeur in Montreal, Montréal, Quebec
Lille University Hospital Center, Lille, Not set
Saint-Antoine Hospital - APHP, Paris, Not set
Tenon Hospital - APHP, Paris, Not set
Hospices Civils de Lyon - Lyon Sud, Pierre-Bénite, Not set
University Hospital Center of Poitiers, Poitiers, Not set
IUCT-Oncopole, Toulouse, Not set
University Hospital Tuebingen, Medical Clinic II, Hematology, Oncology, Clinical Immunology and Rheumatology, Tuebingen, Baden-Wuerttemberg
Hospital Rechts der Isar of the Technical University of Munich, Clinic and Polyclinic for Internal Medicine III: Hematology and Internal Oncology, Munich, Bavaria
University Hospital Duesseldorf, Duesseldorf, North Rhine-Westphalia
University Hospital Carl Gustav Carus Dresden, Medical Clinic and Polyclinic I, Dresden, Saxony
University Hospital Schleswig-Holstein, Luebeck, Schleswig-Holstein
University Hospital Hamburg-Eppendorf, Hamburg, Not set
Hospital San Raffaele, IRCCS, Unit of Immunology, Rheumatology, Allergy and Rare Diseases, Milan, Not set
University Hospital of Padova, Rheumatology Unit, Department of Medicine - DIMED, Padova, Not set
AUSL of Reggio Emilia - Hospital Arcispedale S. Maria Nuova, Complex Structure of Rheumatology, Reggio Emilia, Not set
Foundation PTV - Polyclinic Tor Vergata Biomedicine and prevention, Roma, Not set
Fukushima Medical University Hospital, Fukushima, Not set
Nagasaki University Hospital, Nagasaki, Not set
Yokohama City University Hospital, Yokohama, Not set
Hospital Clinic of Barcelona, Barcelona, Not set
Catalan Institute of Oncology, Hospital Duran i Reynals, Department of Clinical Hematology, Hospitalet de Llobregat, Not set
University Clinical Hospital of Salamanca, Salamanca, Not set
St James's University Hospital, Leeds, Not set
Royal Free Hospital, London, Not set
King's College Hospital, Department of Hematology, London, Not set
Churchill Hospital, Oxford, Not set
Conditions: VEXAS, VEXAS Syndrome
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
Recruiting
The purpose of this study is to evaluate the efficacy, safety and PK of aficamten in a pediatric population with symptomatic obstructive hypertrophic cardiomyopathy (oHCM).
The purpose of this study is to evaluate the efficacy, safety and PK of aficamten in a pediatric population with symptomatic obstructive hypertrophic cardiomyopathy (oHCM). Read Less
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
08/11/2025
Locations: Children's Hospital Los Angeles, Los Angeles, California +30 locations
Children's Hospital Los Angeles, Los Angeles, California
University of California, Los Angeles (UCLA), Los Angeles, California
UCSF Benioff Children's Hospital, San Francisco, California
Children's Hospital Colorado, Aurora, Colorado
Children's National Hospital, Washington, District of Columbia
Nicklaus Children's Hospital, Miami, Florida
Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois
University of Iowa, Iowa City, Iowa
Children's Hospital New Orleans, New Orleans, Louisiana
University of Michigan, Ann Arbor, Michigan
Children's Hospital of Michigan, Detroit, Michigan
Mayo Clinic, Rochester, Minnesota
Children's Mercy Hospital, Kansas City, Missouri
University of Nebraska Medical Center, Omaha, Nebraska
Morristown Medical Center, Morristown, New Jersey
Children's Hospital at Montefiore, Bronx, New York
NYP/Columbia University Medical Center, New York, New York
Duke Clinical Research Institute, Durham, North Carolina
Oregon Health & Science University, Portland, Oregon
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
LeBonheur Children's Hospital, Memphis, Tennessee
Vanderbilt University Medical Center, Nashville, Tennessee
UT Southwestern, Dallas, Texas
Children's Wisconsin, Milwaukee, Wisconsin
The Hospital for Sick Children (SickKids), Toronto, Ontario
Careggi University Hospital, Florence, Not set
Unidad de Cardiología Infantil; Hospital Universitario da Coruña, A Coruña, Not set
Hospital Sant Joan de Deu, Barcelona, Not set
Alder Hey Children's Hospital, Liverpool, Not set
Royal Brompton Hospital, London, Not set
Great Ormond Street Hospital for Children, London, Not set
Conditions: Pediatric, Symptomatic Obstructive Hypertrophic Cardiomyopathy
A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer
Recruiting
This study aims to investigate the combination of BNT324, a B7-H3 antibody-drug conjugate (ADC) with BNT327, a programmed death-ligand 1 (PD-L1) and vascular endothelial growth factor (VEGF) bispecific antibody, in participants with advanced/metastatic or relapsed/progressive small cell lung cancer (SCLC) and non small cell lung cancer (NSCLC).
This study aims to investigate the combination of BNT324, a B7-H3 antibody-drug conjugate (ADC) with BNT327, a programmed death-ligand 1 (PD-L1) and vascular endothelial growth factor (VEGF) bispecific antibody, in participants with advanced/metastatic or relapsed/progressive small cell lung cancer (SCLC) and non small cell lung cancer (NSCLC). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/11/2025
Locations: Precision NextGen Oncology and Research Center, Beverly Hills, California +5 locations
Precision NextGen Oncology and Research Center, Beverly Hills, California
John Theurer Cancer Center at Hackensack UMC, Hackensack, New Jersey
Virginia Cancer Specialists, Fairfax, Virginia
Hacettepe University Medical Faculty, Ankara, Not set
Bristol Haematology and Oncology Centre, Bristol, Not set
University College London Hospital, London, Not set
Conditions: Advanced Lung Cancer
A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome
Recruiting
The purpose of this study is to assess the safety and efficacy of two doses of Deucravacitinib in adult participants with Active Sjögren's Syndrome.
The purpose of this study is to assess the safety and efficacy of two doses of Deucravacitinib in adult participants with Active Sjögren's Syndrome. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/11/2025
Locations: Local Institution - 0228, Fullerton, California +228 locations
Local Institution - 0228, Fullerton, California
Arthritis and Osteoporosis Medical Center, La Palma, California
UCSF Univ of California San Francisco, San Francisco, California
Providence St. John's Health Center, Santa Monica, California
Denver Arthritis Clinic, Denver, Colorado
Clinical Research of West Florida; Inc, Clearwater, Florida
GNP Research, Cooper City, Florida
Sarasota Arthritis Center, Sarasota, Florida
Augusta University, Augusta, Georgia
Local Institution - 0229, Lawrenceville, Georgia
Clinic of Robert Hozman/Clinical Investigation Specialists Inc., Skokie, Illinois
University of Kansas Medical Center, Kansas City, Kansas
Local Institution - 0123, Hopkinsville, Kentucky
Ochsner Health Center - Baton Rouge, Baton Rouge, Louisiana
Local Institution - 0125, Monroe, Louisiana
Johns Hopkins Medicine - Jerome L. Greene Sjogrens Syndrome Center, Baltimore, Maryland
Tufts Medical Center, Boston, Massachusetts
Saint Paul Rheumatology, Eagan, Minnesota
Institute for Rheumatic & Autoimmune Diseases; Overlook Medical Center, Summit, New Jersey
Local Institution - 0009, Albuquerque, New Mexico
NYU Langone Hospital - Long Island, Mineola, New York
Onsite Clinical Solutions, Salisbury, North Carolina
Local Institution - 0132, Corvallis, Oregon
Altoona Center for Clinical Research, Duncansville, Pennsylvania
Local Institution - 0022, Jackson, Tennessee
Arthritis & Rheumatology Research Institute; PLLC, Allen, Texas
Biopharma Informatic, Katy, Texas
Local Institution - 0175, Plano, Texas
Local Institution - 0225, The Woodlands, Texas
Local Institution - 0133, Seattle, Washington
Arthritis Northwest, Spokane, Washington
IMAC SI, San Isidro, Alabama
Iro Research, Caba, Buenos Aires
CER Instituto Medico, Quilmes, Buenos Aires
Centro de Investigaciones Medicas Tucuman, San Miguel de Tucuman, Tucuman
Centro Medico del Dr Javier Tartaglione, Buenos Aires, Not set
Local Institution - 0058, Buenos Aires, Not set
IME Instituto medico Especializado, Caba, Not set
Centro Barrio Parque - Swiss Medical, City of Buenos Aires, Not set
Consultora Integral de Salud SRL, Cordoba, Not set
Local Institution - 0039, Cordoba, Not set
The Queen Elizabeth Hospital, Woodville South, South Australia
Local Institution - 0165, Nedlands, Western Australia
Medical University of Graz, Graz, Not set
Local Institution - 0087, Wien, Not set
Local Institution - 0183, Aalst, Not set
UZ Gent, Gent, Not set
Hospital Universitario Cassiano Antonio Moraes, Vitoria, ES
Cmip-Centro Mineiro de Pesquisa, Juiz de Fora, MG
Universidade Federal de Minas Gerais (UFMG) - Faculdade de Medicina, Belo Horizonte, Minas Gerais
Hospital Moinhos de Vento, Porto Alegre, RS
CEPIC Centro Paulista de Investigacao Clinica, Sao Paulo, SP
Universidade Federal de Uberlandia (UFU) - Campus Santa Monica - Centro de Pesquisa Clinica, Uberlandia, Not set
Local Institution - 0008, Plovdiv, Not set
ARENSIA Research Clinic MBAL Sveta Sofia, Sofia, Not set
Sjogren's Clinic at the Mary Pack Arthritis Center, Vancouver, British Columbia
University Health Network - Toronto Western Hospital, Toronto, Ontario
Diex Recherche Sherbrooke, Sherbrooke, Quebec
Centre De Recherche Musculo-Squelettique, Trois Rivières, Quebec
Clinical Research Chile SpA, Valdivia, LOS Lagos
Local Institution - 0103, Valdivia, Los Rios
BioMedica Research Group, Santiago, Metropolitana
Centro de Estudios Reumatologicos, Santiago, Providencia
Local Institution - 0015, Santiago De Chlie, Region Metropolitana
CIERI, Vina Del Mar, Valparaiso
Local Institution - 0099, Osorno, Not set
Estudios Clinicos GyC, Santiago, Not set
Local Institution - 0121, Santiago, Not set
Peking University First Hospital (Beida Hospital) (No.1 Hospital Affiliated to Beijing Medical University), Beijing Shi, Beijing
Peking University People's Hospital - Institute of Rheumatology and Immunology, Beijing, Beijing
Peking University Third Hospital, Beijing, Beijing
Local Institution - 0096, Chongqing, Chongqing
The First Affiliated Hospital of Xiamen University, Xiamen, Fujian
Guangdong Provincial People's Hospital, Guangzhou, Guangdong
Shenzhen Peoples Hospital, Shenzhen, Guangdong
Local Institution - 0180, Luoyang, Henan
1st Hospital of Zhengzhou University, Zhengzhou, Henan
Tongji Hospital affiliated to Huazhong University of Science and Technology, Wuhan, Hubei
The Second Xiangya Hospital of Central South University, Changsha, Hunan
Hunan Province People's Hospital, Changsha, Hunan
Local Institution - 0098, Baotou Shi, Inner Mongolia
Local Institution - 0150, Hohhot, Inner Mongolia
Nanjing Drum Tower hospital, Nanjing, Jiangsu
Nanjing Medical University (NMU) - Jiangsu Province Hospital (First Affiliated Hospital), Nanjing, Jiangsu
Ningbo First Hospital, Ningbo, Jiangsu
Local Institution - 0154, Suzhou, Jiangsu
Local Institution - 0163, Jiujiang, Jiangxi
1st Hospital of Nanchang University, Nanchang, Jiangxi
Jiangxi Provincial Peoples Hospital, Nanchang, Jiangxi
Pingxiang Peoples Hospital, Pingxiang, Jiangxi
The First Affiliated Hospital of Xian Jiaotong University, Xian, Shaanxi
Shanxi Bethune Hospital;Shanxi Academy of Medical Sciences, Taiyuan, Shan1xi
Shanghai 9th Peoples Hospital, Shanghai Shi, Shanghai Sheng
Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine -Shanghai Institute of Rheumatology, Shanghai, Shanghai
Tongji University - Tongji Hospital, Shanghai, Shanghai
West China Hospital Sichuan University, Chengdu, Sichuan
Xinjiang Uygur Autonomous Region People's Hospital, Urumqi, Xinjiang Sheng
Local Institution - 0181, Hangzhou, Zhejiang
Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang
Wenzhou Medical University (WMU) - The First Affiliated Hospital, Wenzhou, Zhejiang
Local Institution - 0168, Barranquilla, Atlantico
Local Institution - 0043, Chica, Cundinamarca
Local Institution - 0037, Bogota D.C, Not set
Local Institution - 0186, Aarhus, Region Midt
Local Institution - 0006, Glostrup, Not set
Meilahti Triangle Hospital, Helsinki, Not set
Satucon Oy, Kuopio, Not set
Turku University Hospital, Turku, Not set
Hopital de la Pitie Salpetriere, Paris, Cedex 13
Local Institution - 0072, Orleans, Centre
CHU Amiens-Picardie - Site Nord Hopital Nord, Amiens, Not set
CHU de Bordeaux - Hopital Saint-Andre, Bordeaux, Not set
Local Institution - 0070, Grenoble, Not set
Groupe Hospitalier du Havre (GHH) - Hopital Jacques Monod, Le Havre Cedex, Not set
CHU Hpital de Bicetre Universit Paris 11, Le Kremlin-Bictre, Not set
Local Institution - 0078, Marseille, Not set
Hopital Saint Antoine, Paris, Not set
Hopital Cochin, Paris, Not set
Klinikum der Universitaet Muenchen LMU, Munich, Bayern
Charite University Hospitals, Berlin, Not set
University Hospital Freiburg, Freiburg, Not set
Hamburger Rheuma Forschungszentrum 2, Hamburg, Not set
Universitaetsklinikum Tuebingen, Tuebingen, Not set
Universitaetsklinikum Wuerzburg, Wuerzburg, Not set
National and Kapodistrian University of Athens NKUA - Laiko General Hospital, Athens, Not set
Local Institution - 0052, Athina, Not set
Local Institution - 0108, Larissa, Not set
Local Institution - 0115, Budapest, IX, Válassz Egy Opciót…
Local Institution - 0113, Budapest, Not set
Debreceni Egyetem - Orvos es Egeszsegtudomanyi Centrum (DEOEC) (University of Debrecen Medical and Health Science Center), Debrecen, Not set
Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz, Gyula, Not set
Sheba Medical Center, Ramat Gan, IA
Meir Medical Center, Kfar Sava, Not set
Asst Spedali Civili Di Brescia, Brescia, Not set
ASST G. Pini-CTO, Milano, Not set
Università degli Studi della Campania Luigi Vanvitelli Napoli, Napoli, Not set
Local Institution - 0082, Padua, Not set
AOU Pisana, Pisa, Not set
Campus Biomedico University, Rome, Not set
Local Institution - 0062, Rome, Not set
Santa Maria della Misericordia, Udine, Not set
Kojunkai Daido Clinic, Nagoya-shi, Aichi
Fujita Health University Hospital, Toyoake-shi, Aichi
Hospital of the University of Occupational and Environmental Health, Kitakyushu-shi, Fukuoka
Hokkaido University Hospital, Sapporo-shi, Hokkaido
Sapporo Medical University Hospital, Sapporo, Hokkaido
Hyogo Medical University Hospital, Nishinomiya-shi, Hyogo
Tsukuba University Hospital, Tsukuba City, Ibaraki
Kanazawa Medical University Hospital, Kahoku-gun, Ishikawa
Kanazawa University Hospital, Kanazawa-shi, Ishikawa
St.Marianna University Hospital, Kawasaki-shi, Kanagawa
National Hospital Organization Yokohama Medical Center, Yokohama, Kanagawa
Tohoku University Hospital, Sendai-shi, Miyagi
Nagasaki University Hospital, Nagasaki-Shi, Nagasaki
Sasebo Chuo Hospital, Sasebo, Nagasaki
Kurashiki Medical Clinic, Kurashiki, Okayama
Shiga University of Medical Science Hospital, Otsu, Shiga
Hamamatsu University Hospital, Hamamatsu, Shizuoka
Dokkyo Medical University Hospital, Shimotsugagun, Tochigi
Juntendo University Hospital, Bunkyo-ku, Tokyo
Institute of Science Tokyo Hospital, Bunkyo-ku, Tokyo
St. Luke's International Hospital, Chuo-ku, Tokyo
Nihon University Itabashi Hospital, Itabashi City, Tokyo
National Hospital Organization Tokyo Medical Center, Meguro-ku, Tokyo
Toho University Ohashi Medical Center, Meguro-ku, Tokyo
Showa University East Hospital, Shinagawa-ku, Tokyo
Keio University Hospital, Shinjuku, Tokyo
Hanyang University Seoul Hospital, Seongdong-gu, Seoul
Local Institution - 0042, Gwangju, Not set
The Catholic University of Korea; Seoul St. Mary's Hospital, Seoul, Not set
Konkuk University Medical Center, Seoul, Not set
CINTRE - Centro de investigacion y tratamiento reumatologico, S.C., Mexico, Distrito Federal
Consultorio Medico de Reumatologia, Leon, Guanajuato
Investigacion Biomedica para el Desarrollo de Farmacos S.A de C.V, Guadalajara, Jalisco
Centro de Estudios de Investigacion Basica y Clinica S.C., Guadalajara, Jalisco
Local Institution - 0021, Chihuahua, Not set
Local Institution - 0046, Leeuwarden, Friesland
Universitair Medisch Centrum Groningen, Groningen, Not set
Erasmus Medisch Centrum, Rotterdam, Not set
ACQ Medic SAC, Jesus Maria, Lima
Instituto de Ginecologia y Reproduccion, Santiago de Surco, Lima
Clinica Internacional Sede Lima, Lima, Not set
Centrum Medyczne PLEJADY, Krakow, Malopolskie
MICS Centrum Medyczne Warszawa, Warszawa, Mazowieckie
Local Institution - 0141, Warszawa, Woj. Mazowieckie
Local Institution - 0010, Warszawa, Woj. Mazowieckie
MICS Centrum Medyczne Bydgoszcz, Bydgoszcz, Not set
Szpital Uniwersytecki nr 2 im.dr. Jana Biziela w Bydgoszczy, Bydgoszcz, Not set
Etg Network, Lublin, Not set
Med-Polonia Sp. zo.o., Poznan, Not set
Reuma Park Warszawa, Warsawa, Not set
FutureMeds Targowek, Warsaw, Not set
Narodowy Instytut Geriatrii; Reumatologii i Rehabilitacji, Warszawa, Not set
Niepubliczny Zaklad Opieki Zdrowotnej Biogenes Sp. z o.o., Wroclaw, Not set
Dolnoslaski Szpital Specjalistyczny im. Tadeusza Marciniaka, Wroclaw, Not set
Instituto Portugues de Reumatologia, Lisboa, Not set
Centro Hospitalar Universitario Lisboa Norte E.P.E. (CHULN) - Hospital de Santa Maria, Lisboa, Not set
GCM Medical Group, PSC - Hato Rey Site-Hato Rey, San Juan, Not set
Local Institution - 0127, San Juan, Not set
ARENSIA Research Clinic Emergency County Hospital, Cluj-Napoca, Cluj
CMDTA Neomed SRL, Brasov, Not set
Arensia Research Clinic, Bucharest, Not set
Local Institution - 0104, Iasi, Not set
Hospital de Merida, Merida, Badajoz
Hospital Universitario Marques de Valdecilla, Santander, Cantabria
Hospital Universitario De Canarias - San Cristbal de La Laguna, La Laguna, Santa Cruz De Tenerife
Local Institution - 0112, A Coruna, Not set
Clinica GAIAS Santiago, Santiago De Compostela, Not set
Hospital Infantaluisa, Sevilla, Not set
Sahlgrenska University Hospital, Gotenburg, Not set
Karolinska University Hospital, Solna, Not set
Local Institution - 0066, Basel, Baden-Württemberg
Insel Gruppe AG, Bern, Not set
Kantonsspital St. Gallen, Southwest, Not set
Chang Gung Medical Foundation Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City, Not set
China Medical University Hospital CMUH, Taichung, Not set
Local Institution - 0002, Taichung, Not set
National Taiwan University Hospital NTUH, Taipei City, Not set
Chang Gung Medical Foundation Linkou Chang Gung Memorial Hospital, Taoyuan City, Not set
Gazi University Hospital, Yenimahalle, Ankara
Hacettepe University School Of Medicine, Ankara, Not set
Akdeniz University Medical Faculty, Antalya, Not set
Local Institution - 0086, Istanbul, Not set
Istanbul University Cerrahpasa Medical School, Istanbul, Not set
Southampton General Hospital - University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire
Local Institution - 0053, Newcastle Upon Tyne, Tyne And Wear
New Cross Hospital, Wolverhampton, West Midlands
University of Birmingham - Queen Elizabeth Hospital, Birmingham, Not set
Cannock Chase Hospital, Cannock, Not set
Conditions: Sjögren's Syndrome
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