All Clinical Trials in United Kingdom

A listing of 3097 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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A Study Evaluating APG777 in Atopic Dermatitis

NCT06395948

Recruiting

This is a two-part study that will evaluate the safety and efficacy of APG777 in participants with moderate-to-severe Atopic Dermatitis (AD). Part A (Proof-of-concept) and Part B (Dose-regimen Finding) will evaluate the safety and efficacy of various induction and maintenance dose regimens of APG777 compared to placebo. The study duration for any individual participant will be up to 106 weeks which includes: screening, induction, maintenance, and post-treatment follow-up periods. Participants ra... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Investigational Site, Fountain Valley, California +90 locations

Investigational Site, Fountain Valley, California

Investigational Site, Los Angeles, California

Investigational Site, San Diego, California

Investigational Site, New Haven, Connecticut

Investigational Site, Coral Gables, Florida

Investigational Site, Jacksonville, Florida

Investigational Site, Margate, Florida

Investigational Site, Douglasville, Georgia

Investigational Site, Chicago, Illinois

Investigational Site, Skokie, Illinois

Investigational Site, West Lafayette, Indiana

Investigational Site, Bowling Green, Kentucky

Investigational Site, Rockville, Maryland

Investigational Site, Detroit, Michigan

Investigational Site, Troy, Michigan

Investigational Site, Portsmouth, New Hampshire

Investigational Site, New York, New York

Investigational Site, Wilmington, North Carolina

Investigational Site, Boardman, Ohio

Investigational Site, Mason, Ohio

Investigational Site, Portland, Oregon

Investigational Site, Pittsburgh, Pennsylvania

Investigational Site, Charleston, South Carolina

Investigational Site, Nashville, Tennessee

Investigational Site, Dallas, Texas

Investigational Site, San Antonio, Texas

Investigational Site, Norfolk, Virginia

Investigational Site, Mill Creek, Washington

Investigational Site, Calgary, Alberta

Investigational Site, Edmonton, Alberta

Investigational Site, Vancouver, British Columbia

Investigational Site, Winnipeg, Manitoba

Investigational Site, Fredericton, New Brunswick

Investigational Site, Ajax, Ontario

Investigational Site, Markham, Ontario

Investigational Site, Mississauga, Ontario

Investigational Site, Ottawa, Ontario

Investigational Site, Peterborough, Ontario

Investigational Site, Toronto, Ontario

Investigational Site, Montreal, Quebec

Investigational Site, Québec, Quebec

Investigational Site, Prague 5, Not set

Investigational Site, Prague, Not set

Investigational Site, Rouen, Normandie

Investigational Site, Martigues, Not set

Investigational Site, Nantes, Not set

Investigational Site, Heidelberg, Baden-Wurttemberg

Investigational Site, Freiburg, Baden-Württemberg

Investigational Site, Tuebingen, Baden-Württemberg

Investigational Site, Augsburg, Bavaria

Investigational Site, München, Bayern

Investigational Site, Blankenfelde-Mahlow, Brandenburg

Investigational Site, Darmstadt, Hessen

Investigational Site, Frankfurt, Hesse

Investigational Site, Bad Bentheim, Lower Saxony

Investigational Site, Münster, North Rhine Westfalia

Investigational Site, Dresden, Saxony

Investigational Site, Kiel, Schleswig-Holstein

Investigational Site, Luebeck, Schleswig-Holstein

Investigational Site, Berlin, Not set

Investigational Site, Hamburg, Not set

Investigational Site, Debrecen, Hajdú-Bihar

Investigational Site, Budapest, Not set

Investigational Site, Wrocław, Dolnoslaskie

Investigational Site, Lublin, Lubelskie

Investigational Site, Warsaw, Mazowieckie

Investigational Site, Warszawa, Mazowieckie

Investigational Site, Gdańsk, Pomorskie

Investigational Site, Katowice, Silesia

Investigational Site, Sosnowiec, Silesia

Investigational Site, Kraków, Woj. Małopolskie

Investigational Site, Szczecin, Zachodniopomorskie

Investigational Site, Łódź, Łódzkie

Investigational Site, Santiago De Compostela, A Coruña

Investigational Site, Badalona, Barcelona

Investigational Site, Las Palmas De Gran Canaria, Islas Canarias

Investigational Site, Alicante, Not set

Investigational Site, Barcelona, Not set

Investigational Site, Madrid, Not set

Investigational Site, Zaragoza, Not set

Investigational Site, Dudley, West Midlands

Investigational Site, London, Not set

Conditions: Atopic Dermatitis

Learn More ›

Vercise™ DBS Dystonia Prospective Study

NCT02686125

Recruiting

To compile characteristics of real-world outcomes of Boston Scientific Corporation's commercially approved VerciseTM Deep Brain Stimulation (DBS) Systems for the treatment of dystonia.

Gender:

ALL

Ages:

7 years and above

Trial Updated:

08/11/2025

Locations: AZ Sint-Lucas, Ghent, Not set +35 locations

AZ Sint-Lucas, Ghent, Not set

UZ Gasthuisberg, Leuven, Not set

Queen Elizabeth II Health Sciences Center, Halifax, Not set

University Berlin, Charite Virchow Standort, Wedding, Berlin, Not set

Universitaetsklinikum Dusseldorf, Dusseldorf, Not set

Universitaetsklinikum Freiburg, Freiburg im Breisgau, Not set

Universitaetsklinik Eppendorf, Hamburg, Not set

St. Barbara-Klinik Hamm-Heessen, Hamm, Not set

Medizinische Hochschule Hannover MHH, Hannover, Not set

Universitatsklinikum Campus Kiel, Kiel, Not set

Uniklinik Köln, Köln, Not set

Johannes Gutenberg Universitaet Mainz, Mainz, Not set

Universitaetsklinikum Giessen und Marburg GmbH, Marburg, Not set

Evangelisches Krankenhaus Oldenburg, Oldenburg, Not set

Universitaetsklinikum Wuerzburg, Würzburg, Not set

Medical School of University PECS, Pecs, Not set

Hadassah Hebrew University Medical Center, Jerusalem, Not set

Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Not set

Ospedale Dell Angelo, Mestre, Not set

Policlinico Universitario Agostino Gemelli, Rome, Not set

Osp. S. Maria Della Misericordia, Udine, Not set

St. Mary's Hospital Incheon, Incheon, Not set

Haga Ziekenhuis locatie Leyweg, Den Haag, Not set

10 Military Clinical Hospital Bydgoszcz, Bydgoszcz, Not set

Wojewodzki Szpital Dzieciecy Jozefa Brudzinskiego (Childrens Hospital Bydgoszcz), Bydgoszcz, Not set

Podmiot Leczniczy Copernicus Sp. z o.o., Gdansk, Not set

Centrum Onkologii - Instytut im. Marii Sklodowskiej-Curie, Warsaw, Not set

National Scientific Center of Neurosurgery N.N. Burdenko, Moscow, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

University Hospital Virgen Arrixaca, El Palmar, Not set

Centro Especial Ramon y Cajal, Madrid, Not set

Hospital General De Asturias, Oviedo, Not set

Southmead Hospital Bristol, Bristol, Not set

Queen Elizabeth University Hospital, Glasgow, Not set

Charing Cross Hospital, London, Not set

Royal Victoria Infirmary, Newcastle Upon Tyne, Not set

Conditions: Dystonia

Learn More ›

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3)

NCT05813288

Recruiting

The objective of this clinical study is to investigate the safety, tolerability, and efficacy of dexpramipexole in participants with inadequately controlled severe eosinophilic asthma.

Gender:

ALL

Ages:

Between 12 years and 99 years

Trial Updated:

08/11/2025

Locations: Research Site 30001-287, Mobile, Alabama +259 locations

Research Site 30001-287, Mobile, Alabama

Research Site 30001-487, Chandler, Arizona

Research Site 30001-462, Peoria, Arizona

Research Site US-30001-462, Peoria, Arizona

Research Site 30001-322, Surprise, Arizona

Research Site 30001-010, Little Rock, Arkansas

Research Site 30001-485, Inglewood, California

Research Site 30001-497, Los Angeles, California

Research Site 30001-489, Pasadena, California

Research Site US-30001-434, San diego, California

Research Site 30001-484, Santa Monica, California

Research Site US-30001-304, Valencia, California

Research Site 30001-305, Valencia, California

Research Site 30001-291, Jacksonville, Florida

Research Site 30001-318, Maitland, Florida

Research Site 30001-311, Miami, Florida

Research Site 30001-288, Miami, Florida

Research Site 30001-310, Miami, Florida

Research Site 30001-329, Miami, Florida

Research Site 30001-082, Miami, Florida

Research Site 30001-301, Naples, Florida

Research Site 30001-348, Ocala, Florida

Research Site 30001-331, Orlando, Florida

Research Site 30001-293, Orlando, Florida

Research Site 30001-312, Pembroke Pines, Florida

Research Site US-30001-429, Plantation, Florida

Research Site 30001-319, Viera, Florida

Research Site US-30001-452, Dunwoody, Georgia

Research Site 30001-483, East Point, Georgia

Research Site 30001-366, Lilburn, Georgia

Research Site 30001-328, Maywood, Illinois

Research Site 30001-347, Louisville, Kentucky

Research Site US-30001-437, Alexandria, Louisiana

Research Site 30001-286, Lafayette, Louisiana

Research Site 30001-313, Marrero, Louisiana

Research Site US-30001-352, Zachary, Louisiana

Research Site US-30001-414, Annapolis, Maryland

Research Site 30001-472, Farmington Hills, Michigan

Research Site 30001-442, Southfield, Michigan

Research Site 30001-372, Warren, Michigan

Research Site 30001-421, Mankato, Minnesota

Research Site 30001-363, Edison, New Jersey

Research Site 30001-474, Massena, New York

Research Site 30001-455, New York, New York

Research Site US-30001-369, New York, New York

Research Site 30001-300, Schenectady, New York

Research Site US-30001-398, Charlotte, North Carolina

Research Site 30001-439, Rocky Mount, North Carolina

Research Site 30001-413, Cleveland, Ohio

Research Site 30001-495, Columbus, Ohio

Research Site US-30001-327, Philadelphia, Pennsylvania

Research Site US-30001-414, Franklin, Tennessee

Research Site US-30001-364, Memphis, Tennessee

Research Site 30001-334, Allen, Texas

Research Site 30001-090, Austin, Texas

Research Site 30001-290, Austin, Texas

Research Site 30001-415, Dallas, Texas

Research Site US-30001-418, Frisco, Texas

Research Site 30001-299, Houston, Texas

Research Site 30001-315, Katy, Texas

Research Site 30001-295, McKinney, Texas

Research Site 30001-373, Mesquite, Texas

Research Site 30001-481, Nederland, Texas

Research Site 30001-297, Pearland, Texas

Research Site 30001-238, San Antonio, Texas

Research Site 30001-377, San Antonio, Texas

Research Site 30001-335, Sugar Land, Texas

Research Site 30001-333, Pleasant View, Utah

Research Site 30054-035, Buenos Aires, Not set

Research Site 30054-031, Buenos Aires, Not set

Research Site 30054-048, Buenos Aires, Not set

Research Site 30054-045, Buenos Aires, Not set

Research Site 30054-026, Buenos Aires, Not set

Research Site 30054-049, Buenos Aires, Not set

Research Site 30054-050, Buenos Aires, Not set

Research Site 30054-044, Buenos Aires, Not set

Research Site -30054-012, Buenos Aires, Not set

Research Site 30054-021, Buenos Aires, Not set

Research Site 30054-034, Buenos Aires, Not set

Research Site 30054-015, Buenos Aires, Not set

Research Site 30054-024, Buenos Aires, Not set

Research Site 30054-008, Buenos Aires, Not set

Research Site -30054-043, Buenos Aires, Not set

Research Site 30054-054, Concepcion del Uruguay, Not set

Research Site 30054-051, Cordoba, Not set

Research Site 30054-052, Cordoba, Not set

Research Site 30054-047, Mendoza, Not set

Research Site 30054-010, Mendoza, Not set

Research Site 30054-032, Mendoza, Not set

Research Site 30054-028, Mendoza, Not set

Research Site 30054-042, Santa Fe, Not set

Research Site 30043-012, Vienna, Not set

Research Site 30055-036, Curitiba, Not set

Research Site 30055-021, Porto Alegre, Not set

Research Site 30055-035, Rio de Janeiro, Not set

Research Site 30055-025, Salvador, Not set

Research Site 30055-025, Sao Paulo, Not set

Research Site 30056-013, Santiago, Providencia

Research Site 30056-009, Curico, Not set

Research Site 30056-007, Santiago, Not set

Research Site 30056-013, Santiago, Not set

Research Site 30056-011, Santiago, Not set

Research Site 30056-010, Santiago, Not set

Research Site 30056-006, Santiago, Not set

Research Site 30056-012, Santiago, Not set

Research Site 30056-005, Temuco, Not set

Research Site 30056-014, Vina Del Mar, Not set

Research Site 20086-021, Shanghai, Not set

Research Site 30385-008, Zadar, Not set

Research Site 30385-002, Zagreb, Not set

Research Site 30385-007, Zagreb, Not set

Research Site 30420-018, Brno, Not set

Research Site 30420-012, Brno, Not set

Research Site 30420-003, Jindrichuv Hradec, Not set

Research Site 30420-007, Lovosice, Not set

Research Site 30420-014, Olomouc, Not set

Research Site 30420-010, Strakonice, Not set

Research Site 30420-009, Teplice, Not set

Research Site 30033-012, Cholet, Not set

Research Site 30033-005, Grenoble Cedex 9, Not set

Research Site 30033-013, Libourne, Not set

Research Site 30033-014, Lille Cedex, Not set

Research Site 30033-002, Lyon Cedex 4, Not set

Research Site 30033-001, Marseille, Not set

Research Site 30033-006, Marseille, Not set

Research Site 30033-007, Montpellier Cedex 5, Not set

Research Site 30033-003, Paris, Not set

Research Site 30033-015, Reims, Not set

Research Site 30033-004, Saint Herblain, Not set

Research Site 30033-018, Strasbourg, Not set

Research Site 30049-081, Augsburg, Not set

Research Site 30049-060, Berlin, Not set

Research Site 30049-005, Berlin, Not set

Research Site 30049-004, Cottbus, Not set

Research Site 30049-082, Delitzsch, Not set

Research Site 30049-059, Frankfurt, Not set

Research Site 30049-019, Frankfurt, Not set

Research Site 30049-006, Furstenwalde, Not set

Research Site 30049-035, Hannover, Not set

Research Site 30049-073, Homburg, Not set

Research Site 30049-061, Leipzig, Not set

Research Site 30049-056, Leipzig, Not set

Research Site 30049-051, Munich, Not set

Research Site 30049-028, Munich, Not set

Research Site 30036-005, Balassagyarmat, Not set

Research Site 30036-001, Budapest, Not set

Research Site 30036-014, Debrecen, Not set

Research Site 30036-017, Edelény, Not set

Research Site 30036-013, Godollo, Not set

Research Site 30036-006, Szeged, Not set

Research Site 30036-018, Szigetvar, Not set

Research Site 30091-006, Ahmedabad, Gujarat

Research Site 30091-010, Ahmedabad, Gujarat

Research Site 30091-011, Himmatnagar, Gujarat

Research Site 30091-001, Sūrat, Gujarat

Research Site 30091-024, Rohtak, Haryana

Research Site 30091-043, Aurangabad, Maharashta

Research Site 30091-004, Nagpur, Maharashta

Research Site 30091-023, Nagpur, Maharashta

Research Site 30091-033, Pune, Maharashta

Research Site 30091-018, Jaipur, Rajasthan

Research Site 30091-021, Kanpur, Not set

Research Site 30972-008, Beer-Sheva, Not set

Research Site 30972-001, Jerusalem, Not set

Research Site 30972-009, Kfar Saba, Not set

Research Site 30972-011, Ramat Gan, Not set

Research Site 30972-012, Reẖovot, Not set

Research Site 30972-005, Sha'ar Ha'Aliya, Not set

Research Site 30039-004, Bergamo, Not set

Research Site 30039-020, Genova, Not set

Research Site 30039-013, Napoli, Not set

Research Site 30039-002, Padova, Not set

Research Site 30039-017, Reggio Emilia, Not set

Research Site 30039-011, Roma, Not set

Research Site 20081-010, Kanazawa, Not set

Research Site 30082-019, Gwangju, Not set

Research Site 30082-022, Seoul, Not set

Research Site 30082-018, Seoul, Not set

Research Site 20082-028, Seoul, Not set

Research Site 30082-010, Suwon, Not set

Research Site 30082-017, Wŏnju, Not set

Research Site 30370-016, Kaunas, Not set

Research Site 30370-017, Klaipeda, Not set

Research Site 30370-002, Vilnius, Not set

Research Site 30052-024, Guadalajara, Jalisco

Research Site 30052-025, Morelia, Michoacon

Research Site 30052-026, Chihuahua, Not set

Research Site 30052-030, Durango, Not set

Research Site 30052-033, Leon, Not set

Research Site 30052-028, Mexico City, Not set

Research Site 30052-023, Monterrey, Not set

Research Site -30051-023, Arequipa, Not set

Research Site 30051-022, Lima, Not set

Research Site 30051-026, Lima, Not set

Research Site 30051-020, Lima, Not set

Research Site -30051-028, Lima, Not set

Research Site 30051-017, Lima, Not set

Research Site 30051-021, Lima, Not set

Research Site 30787-388, Rio Piedras, Not set

Research Site 30001-383, San Juan, Not set

Research Site 30787-405, San Juan, Not set

Research Site 30001-345, Vega Baja, Not set

Research Site 30027-013, Benoni, Not set

Research Site 30027-009, Cape Town, Not set

Research Site 30027-011, Cape Town, Not set

Research Site 30027-012, Cape Town, Not set

Research Site 30027-021, Cape Town, Not set

Research Site 30027-007, Durban, Not set

Research Site 30027-001, Durban, Not set

Research Site 30027-014, Durban, Not set

Research Site 30027-023, Durban, Not set

Research Site 30027-010, Durban, Not set

Research Site 30027-030, Johannesburg, Not set

Research Site 30027-026, Johannesburg, Not set

Research Site 30027-031, Krugersdorp, Not set

Research Site 30027-008, KwaZulu, Not set

Research Site 30027-032, Plettenberg Bay, Not set

Research Site 30027-029, Polokwane, Not set

Research Site 30027-004, Pretoria, Not set

Research Site 30027-019, Pretoria, Not set

Research Site 30027-015, Thabazimbi, Not set

Research Site 30027-018, Vereeniging, Not set

Research Site 30027-017, Welkom, Not set

Research Site 30034-046, A Coruna, Not set

Research Site 30034-052, A Coruna, Not set

Research Site 30034-011, Barcelona, Not set

Research Site 30034-049, Barcelona, Not set

Research Site 30034-013, Barcelona, Not set

Research Site 30034-021, Lugo, Not set

Research Site 30034-053, Madrid, Not set

Research Site 30034-037, Madrid, Not set

Research Site 30034-045, Madrid, Not set

Research Site 30034-050, Santander, Not set

Research Site 30034-043, Valencia, Not set

Research Site 30034-041, Vigo, Not set

Research Site 30886-013, Douliu, Not set

Research Site 30886-004, New Taipei City, Not set

Research Site 30886-006, New Taipei City, Not set

Research Site 30886-005, Taichung, Not set

Research Site 30886-007, Taichung, Not set

Research Site 30886-011, Tainan, Not set

Research Site 30886-010, Taipei, Not set

Research Site 30886-008, Taipei, Not set

Research Site 30886-003, Taipei, Not set

Research Site 30886-009, Taipei, Not set

Research Site 30090-018, Ankara, Not set

Research Site 30090-021, Ankara, Not set

Research Site 30090-008, Ankara, Not set

Research Site 30090-009, Ankara, Not set

Research Site 30090-019, Bornova, Not set

Research Site 30090-020, Istanbul, Not set

Research Site 30090-011, Istanbul, Not set

Research Site 30090-013, Mersin, Not set

Research Site 30090-002, Yüreğir, Not set

Research Site 30380-002, Chernivtsi, Not set

Research Site 30380-011, Kyiv, Not set

Research Site 30044-027, Glasgow, Not set

Research Site 30044-059, High Wycombe, Not set

Research Site 30044-039, Leicester, Not set

Research Site 30044-025, Sheffield, Not set

Conditions: Eosinophilic Asthma, Asthma; Eosinophilic, Asthma

Learn More ›

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

NCT06892548

Recruiting

This study aims to investigate the combination of BNT324, a B7-H3 antibody-drug conjugate (ADC) with BNT327, a programmed death-ligand 1 (PD-L1) and vascular endothelial growth factor (VEGF) bispecific antibody, in participants with advanced/metastatic or relapsed/progressive small cell lung cancer (SCLC) and non small cell lung cancer (NSCLC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Precision NextGen Oncology and Research Center, Beverly Hills, California +5 locations

Conditions: Advanced Lung Cancer

Learn More ›

Inari VISION Registry

NCT06600542

Recruiting

This registry is a global prospective, non-randomized, multicenter, observational, active post-market data collection of Inari Medical devices and products.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Southmead Hospital Bristol, Bristol, Not set +3 locations

Conditions: Pulmonary Embolism

Learn More ›

GB-PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices

NCT07127172

Recruiting

The GB-PRIME Study is an early feasibility study designed to assess the clinical safety and functionality of the Neuralink N1 Implant and R1 Robot. This study involves participants who have tetraparesis, tetraplegia, or a diagnosis that may lead to these conditions. The N1 Implant is a wireless, rechargeable device mounted on the skull, connected to electrode threads that are inserted into the brain by the R1 Robot, which is a robotic device specifically designed for this procedure.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: University College London Hospitals NHS Foundation Trust, London, Greater London +1 locations

Conditions: Tetraplegia/Tetraparesis, Quadriplegia, Quadriplegia/Tetraplegia, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis (ALS), Spinal Cord Injury (Quadraplegia), Spinal Cord Injury, Motor Neuron Disease, Brain Stem Stroke

Learn More ›

Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS

NCT06553625

Recruiting

The objective of this study is to compile real-world outcomes of Boston Scientific commercially approved radiofrequency (RF) ablation systems used in the central nervous system (CNS) for use in functional neurosurgery.

Gender:

ALL

Ages:

All

Trial Updated:

08/11/2025

Locations: Uniklinik Köln, Cologne, Not set +2 locations

Conditions: Parkinson Disease, Dystonia, Essential Tremor, Movement Disorders

Learn More ›

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

NCT06274801

Recruiting

This open-label extension study will evaluate the long-term safety, tolerability and efficacy of orally inhaled seralutinib in subjects who have completed a previous seralutinib study

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/11/2025

Locations: Valley Advanced Lung Diseases Institute, Fresno, California +75 locations

Valley Advanced Lung Diseases Institute, Fresno, California

Department of Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California

UC Davis Health Medical Center, Sacramento, California

Stanford Healthcare, Stanford, California

Piedmont Physicians Pulmonary & Sleep Medicine of Buckhead, Atlanta, Georgia

The Emory Clinic, Atlanta, Georgia

Northside Hospital - Atlanta, Atlanta, Georgia

UI Health Hospital, Chicago, Illinois

University of Kansas Medical Center, Kansas City, Kansas

Norton Pulmonary Specialists, Louisville, Kentucky

University of Nebraska Medical Center, Omaha, Nebraska

University of New Mexico Health Sciences Center, Albuquerque, New Mexico

NYU Langone Health, New York, New York

UNC Hospitals, Chapel Hill, North Carolina

The Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

UPMC Presbyterian Hospital, Pittsburgh, Pennsylvania

Houston Methodist Outpatient Center, Houston, Texas

Intermountain Medical Center, Murray, Utah

Inova Fairfax Medical Campus, Falls Church, Virginia

Pulmonary Associates of Richmond, Inc., Richmond, Virginia

Cardiologia Palermo, Buenos Aires, Not set

Instituto de Cardiologia de Corrientes Juana Francisca Cabral, Corrientes, Not set

Instuto de Investigacion Clinicas Quilmes, Quilmes, Not set

Instituto Medico Rio Cuarto, Río Cuarto, Not set

Hospital Provincial Dr. Jose Maria Cullen, Santa Fe, Not set

Wesley Research Institute, Auchenflower, Not set

St Vincent's Hospital (Melbourne), Fitzroy, Not set

Hopital Erasme, Anderlecht, Not set

Irmandade da Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Not set

Centro de Investigacion Clinica UC-CICUC, Santiago, Not set

Enroll SpA, Santiago, Not set

Institut klinicke a experimentalni mediciny Klinika kardiologie Ambulance plicni hypertenze, Praha, Not set

Všeobecná fakultní nemocnice v Praze ll. interní klinika kardiologie a angiologie VFN a 1.LF UK Centrum pro plicní hvpertenzi, Praha, Not set

Aarhus Universiteshospital, Aarhus, Not set

CHU Bicetre, Service de Pneumologie et Reanimation Respiratorie, Le Kremlin-Bicêtre, Not set

Centre Hospitalier REgional Universitaire de Lille Hopital Cardiologique - Institut Coeur Poumon Service de Cardiologie, Lille, Not set

CHU de Nice - Hopital Pasteur, Nice, Not set

CHU de Poitiers, Poitiers, Not set

Universitätsklinikum Dresden, Medizinische Klinik I / Pneumologisches Studiensekretariat, Dresden, Not set

Universitatsklinikum Giessen und Marburg GmbH Zentrum fur lnnere Medizin, Med. Klinik und Poliklinik II Studienambulanz fur Pulmonale Hypertonie, Gießen, Not set

Thoraxklinik Heidelberg gGmbH am Universitätsklinikum Heidelberg Zentrum für pulmonale Hypertonie, Heidelberg, Not set

Zentrum fur Pulmonale Hypertonie, Klinik Ill fur lnnere Medizin (Kardiologie, Pneumologie, lnternistische lntensivmedizin), Herzzentrum der Universitat zu Koln, Köln, Not set

Krankenhaus Neuwittelsbach, München, Not set

Klinikum Würzburg Mitte gGmbH Medizinische Klinik mit Schwerpunkt Pneumologie und Beatmungsmedizin, Würzburg, Not set

"Evangelismos" General Hospital of Athens, 1st Department of Clinical Care and Pulmonary Hypertension Clinic, Athens, Not set

ATTIKON University Hospital, 2nd Critical Care Department, Athens, Not set

Onassis Cardiac Surgery Center, Non-Invasive Cardiology Department, Kallithéa, Not set

AHEPA University General Hospital of Thessaloniki, 1st Cardiology Clinic, Thessaloníki, Not set

Lady Davis Carmel Medical Center, Haifa, Not set

IRCCS Azienda Ospedaliero Universitaria Di Bologna - Policlinico S. Orsola-Malpighi - UOC Cardiologia, Bologna, Not set

Azienda Ospedaliera Dei Colli - Ospedale Monaldi, Napoli, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

A.O.U. Policlinico Umberto I, Roma, Not set

University of Tokyo Hospital, Bunkyō-Ku, Not set

Nagoya University Hospital, Nagoya, Not set

National Cerebral and Cardiovascular Center, Suita, Not set

Samsung Medical Center, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Pauls Stradins Clinical University Hospital, Riga, Not set

Hospital of Lithuanian University of Health Sciences Kauno klinikos, Kaunas, Not set

Unidad de Investigacion Clinica en Medicina, S.C., Monterrey, Not set

Erasmus MC, Rotterdam, Not set

Europejskie Centrum Zdrowia Otwock Sp.zo.o. Szpital im. Fryderyka Chopina Oddzial Kardiologiczny, Otwock, Not set

Unidade Local de Saude de Santo Antonio, E.P.E. Hospital de Santo Antonio, Porto, Not set

Institutul De Urgenta Pentru Boli Cardiovasculare Prof. Dr. C. C. Iliescu Cardiology 2, Bucharest, Not set

"Niculae Stancioiu" Emergency Heart Institute for Cardiovascular Diseases, Cardiology 1 Department, Cluj-Napoca, Not set

University Clinical Centre of Serbia, Cardiology Clinic, Belgrade, Not set

National Heart Centre Singapore, Singapore, Not set

National University Heart Centre, Singapore, Not set

Hospital Clinic I Provincial, Barcelona, Not set

Hospital Universitario 12 De Octubre, Madrid, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital Universitario de Toledo, Toledo, Not set

Royal Papworth Hospital NHS Foundation Trust, Cambridge, Not set

Golden Jubilee National Hospital, Clydebank, Not set

Hammersmith Hospital, London, Not set

Conditions: Pulmonary Arterial Hypertension

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Alert Frequency, Nurse, and Patient Satisfaction With a wCVSM Software Across Health Care Systems and Cultures

NCT06289699

Recruiting

The goal of this prospective, international multi-centre pilot study is to assess the functionality and user experience of a new vital sign monitoring system in 20 patients and 20 nurses in the general ward at each centre. The patients will be monitored with a wireless, continuous vital sign monitoring systems and answer a questionnaire afterwards. They will in addition have vital signs monitored as per standard practice. The nurses will answer a questionnaire after having had the responsibility... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: The Cleveland Clinic Foundation, General Anesthesiology, Cleveland, Ohio +4 locations

Conditions: User Experience, Postoperative Complications, Acute Medical Conditions

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A Study of MGC026 in Participants With Advanced Solid Tumors

NCT06242470

Recruiting

The study is designed to understand the safety, tolerability, pharmacokinetics, immunogenicity, and preliminary antitumor activity of MGC026 in participants with relapsed or refractory, unresectable, locally advanced or metastatic solid tumors The study has a dose escalation portion and a cohort expansion portion of the study. Participants will receive MGC026 by intravenous (IV) infusion. The dose of MGC026 will be assigned at the time of enrollment. Participants may receive up to 35 treatments... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: The Angeles Clinic and Research Institute, Los Angeles, California +10 locations

Conditions: Advanced Solid Tumor, Advanced Cancer, Metastatic Cancer, Squamous Cell Carcinoma of Head and Neck, Non Small Cell Lung Cancer, Small-cell Lung Cancer, Bladder Cancer, Sarcoma, Endometrial Cancer, Melanoma, Castration Resistant Prostatic Cancer, Cervical Cancer, Colorectal Cancer, Gastric Cancer, Gastro-esophageal Cancer, Pancreas Cancer, Clear Cell Renal Cell Carcinoma, Hepatocellular Carcinoma, Platinum-resistant Ovarian Cancer, Breast Cancer, Ovarian Cancer, Esophageal Squamous Cell Cancer (SCC)

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Evaluation of the Effects of a Nutritional Intervention of Ketogenic Medium-chain Triglycerides and B-vitamins on Cognitive Functioning in Older Adults With Mild Cognitive Impairment (COGNIKET-MCI)

NCT06347315

Recruiting

Evaluation of the Effects of a Nutritional Intervention of Ketogenic Medium-chain Triglycerides and B-vitamins on Cognitive Functioning in Older Adults With Mild Cognitive Impairment (COGNIKET-MCI)

Gender:

ALL

Ages:

60 years and above

Trial Updated:

08/11/2025

Locations: Stein Gerontological Institute Inc, Miami, Florida +29 locations

Stein Gerontological Institute Inc, Miami, Florida

University of Rochester, Rochester, New York

Hôpital Pierre Wertheimer, Bron, Not set

CHU de Montpellier - Hôpital Gui de Chauliac, Montpellier, Not set

CHU de Nantes - Hôpital Nord Laennec, Nantes, Not set

CHU de Toulouse - Gerontopole, Toulouse, Not set

Klinikum Bayreuth GmbH - Klinik Hohe Warte, Bayreuth, Not set

Studienzentrum für Neurologie und Psychiatrie, Böblingen, Not set

Neuro Centrum Science GmbH, Erbach, Not set

Universitaetsmedizin Ulm, Ulm, Not set

Foundation Institute G.Giglio, Cefalu, Not set

IRCCS Ospedale Policlinico San Martino, Genova, Not set

Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone", Palermo, Not set

AOU Policlinico Umberto I - Sapienza Università di Roma, Roma, Not set

Azienda Ospedaliera SantAndrea, Roma, Not set

Laboratory of Neuropsyichiatry, Fondazione Santa Lucia IRCCS, Roma, Not set

Policlinico Universitario Agostino Gemelli, Roma, Not set

AO Card. G. Panico, Tricase, Not set

Hospital Universitario del Vinalopó, Alicante, Not set

Fundaciò ACE, Barcelona, Not set

HGU Gregorio Marañón, Madrid, Not set

Unidad de Investigación Neurociencias Centro de Salud San Juan, Salamanca, Not set

Hospital Universitari General de Catalunya, Sant Cugat Del Vallès, Not set

Hospital Universitario Victoria Eugenia, Sevilla, Not set

Hospital Universitari i Politecnic La Fe, Valencia, Not set

Universitare Altersmedizin FELIX PLATTER, Basel, Not set

Spitalzentrum Centre Hospitalier Biel-Bienne AG (SZB), Biel, Not set

CHUV, Lausanne, Not set

Sussex Partnership NHS foundation Trust, Crowborough, Not set

Hampshire & Isle of Wight Healthcare NHS Foundation Trust, Southampton, Not set

Conditions: Mild Cognitive Impairment

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A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

NCT05611801

Recruiting

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called marstacimab) for the potential treatment of hemophilia in pediatric patients. This study will enroll pediatric participants from ages 1 to 17 years in a sequential manner. The study will open enrollment to adolescent participants aged 12 to 17 years first. Then children aged 6 to 11 years will be permitted to enroll. Lastly, children aged 1 to 5 years will be permitted to enroll. This study will enroll participants who: * have severe Hemophilia A or moderately severe to severe Hemophilia B (with or without inhibitors) * have accurate historical records documenting all factor VIII, factor IX, or bypass agent infusions and hemophilia bleed events for at least 1 year prior to entering the study * if a non-inhibitor patient, must be on a stable routine prophylaxis regimen with factor VIII or factor IX replacement products for at least 12 months prior to study entry * if an inhibitor patient, must be on an on-demand bypass treatment regimen during the 12 months prior to study entry All participants in this study will receive marstacimab to use prophylactically. Marstacimab will be given once a week as a subcutaneous (under the skin) shot. The first dose of marstacimab will be given at the study site by the study site staff. During the 12-month treatment period, weekly doses of marstacimab can be given at home, or if preferred, the doses may be given by the study site staff. To help us determine if the study medicine is safe and effective, we will compare participant experiences when they are taking the study medicine to a historical period when they were not. Researchers want to see if the study medicine works to prevent the bleeding episodes commonly experienced by patients with Hemophilia. Participants will be in this study for about 14 months (approximately 1 month in a Screening period, 12 months receiving treatment, and 1 month in a follow-up period) during which they will visit the study site at least 10 times. If preferred, and if local regulations allow it, 2 of the study visits can be completed at the participant's home instead of at the study site. There will also be 6 scheduled telephone calls approximately every 2 months. Read Less

Gender:

MALE

Ages:

Between 1 year and 17 years

Trial Updated:

08/11/2025

Locations: Intermountain - Primary Children's Hospital, Salt Lake City, Utah +59 locations

Intermountain - Primary Children's Hospital, Salt Lake City, Utah

Arbesu Hematología, Mendoza, Not set

Sydney Children's Hospital, Randwick, New South Wales

Royal Children's Hospital, Melbourne, Victoria

Medizinische Universität Wien, Vienna, Wien

HEMOES, Vitoria, Espírito Santo

Stollery Children's Hospital, Edmonton, Alberta

Hamilton Health Sciences - McMaster University Medical Centre, Hamilton, Ontario/canada

Beijing Children's hospital, Capital Medical University, Beijing, Beijing

Southern Medical University Nanfang Hospital, Guangzhou, Guangdong

The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou

Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei

Tongji Hospital of Tongji Medical College of HUST/Pediatric Hematology Department Pharmacy, Wuhan, Hubei

Jiangxi Provincial People's Hospital, Nanchang, Jiangxi

Institute of hematology&blood disease hospital, Tianjin, Tianjin

Detska nemocnice FN Brno, Brno, Brno-město

Rigshospitalet, Copenhagen, Hovedstaden

Aarhus Universitetshospital, Skejby, Aarhus, Midtjylland

Hôpital Universitaire Necker Enfants Malades, Paris, Not set

Charité Campus Virchow-Klinikum, Berlin, Not set

Nirmal Hospital Pvt Ltd., Surat, Gujarat

K.J. Somaiya Hospital, Mumbai, Maharashtra

Nil Ratan Sircar Medical College and Hospital, Kolkata, WEST Bengal

Sheba Medical Center, Ramat Gan, Hamerkaz

IRCCS Istituto Giannina Gaslini, Genova, Liguria

Istituto Clinico Humanitas, Rozzano, Milano

Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Roma

Azienda Ospedaliero Universitaria di Parma, Parma, Not set

Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Torino, Not set

Hyogo prefectural Kobe Children's Hospital, Kobe, Hyogo

Nagano Children's Hospital, Azumino, Nagano

Nara Medical University Hospital, Kashihara, Nara

Saitama Prefectural Children's Medical Center, Saitama-shi, Saitama

Saga University Hospital, Saga, Not set

Severance Hospital, Yonsei University Health System, Seoul, Seoul-teukbyeolsi [seoul]

Kyung Hee University Hospital at Gangdong, Seoul, Seoul-teukbyeolsi [seoul]

Kyungpook National University Hospital, Daegu, Taegu-kwangyǒkshi

Arké SMO S.A de C.V, Veracruz, Not set

King Fahad Specialist Hospital - Dammam, Dammam, ASH Sharqīyah

King Faisal Specialist Hospital & Research Center, An Narjis, Not set

Detska fakultna nemocnica Kosice, Kosice, Not set

Univerzitna nemocnica Martin, Martin, Not set

Worthwhile Clinical Trials, Benoni, Gauteng

Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, Gauteng

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Changhua Christian Hospital, Changhua County, Changhua

Taichung Veterans General Hospital, Taichung, Not set

National Taiwan University Hospital, Taipei, Not set

Istanbul Universitesi Istanbul Tıp Fakultesi Hastanesi, İstanbul, İ̇stanbul

Ege Universitesi Hastanesi, Izmir, İ̇zmir

Erciyes University, Talas, Kayseri

Acibadem Adana Hospital, Adana, Not set

Gazi University Health Research and Application Center Gazi Hospital, Ankara, Not set

Erciyes Universitesi Tıp Fakultesi Hastaneleri, Kayseri, Not set

Ondokuz Mayıs Universitesi, Samsun, Not set

Royal Victoria Infirmary, Newcastle upon Tyne, England

Birmingham Children's Hospital, Birmingham, Not set

Evelina London Children's Hospital, London, Not set

Royal Manchester Children's Hospital, Manchester, Not set

Conditions: Hemophilia A, Hemophilia B

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