All Clinical Trials in United Kingdom

A listing of 3097 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

NCT02960022

Recruiting

The purpose of this study is to collect long term safety data in subjects who are continuing to derive clinical benefit from treatment with Enzalutamide from the subjects participation in an enzalutamide clinical study sponsored by Astellas or Medivation (i.e., parent study) which has completed, at a minimum, the primary analysis or the study specified evaluation period.

Gender:

MALE

Ages:

18 years and above

Trial Updated:

07/31/2025

Locations: Site US10052, Anchorage, Alaska +235 locations

Site US10052, Anchorage, Alaska

Site US10011, Tucson, Arizona

Site US10040, Los Angeles, California

Site US10009, Los Angeles, California

Site US10067, Orange, California

Site US10008, San Bernardino, California

Site US10042, San Diego, California

Site US10028, Stanford, California

Site US10001, Aurora, Colorado

Site US10017, Denver, Colorado

Site US10050, Washington, District of Columbia

Site US10049, Daytona Beach, Florida

Site US10048, Jacksonville, Florida

Site US10002, Chicago, Illinois

Springfield Clinic, LLP, Springfield, Illinois

Site US10007, Jeffersonville, Indiana

University of Kansas Medical Center, Kansas City, Kansas

Site US10066, Lenexa, Kansas

Site US10029, Towson, Maryland

Site US10032, Saint Louis, Missouri

Nebraska Medical Hospital, Omaha, Nebraska

Site US10023, Omaha, Nebraska

Site US10004, Hackensack, New Jersey

Site US10024, Garden City, New York

Site US10055, New York, New York

Site US10059, New York, New York

Hudson Valley Urology, PC, Poughkeepsie, New York

Site US10053, Syracuse, New York

Site US10030, Chapel Hill, North Carolina

Site US10062, Charlotte, North Carolina

Site US10020, Concord, North Carolina

Site US10031, Greensboro, North Carolina

Eastern Urological Associates, Greenville, North Carolina

Site US10046, Winston-Salem, North Carolina

Site US10035, Cincinnati, Ohio

Site US10022, Springfield, Oregon

Site US10027, Lancaster, Pennsylvania

Site US10005, Pittsburgh, Pennsylvania

Site US10018, Charleston, South Carolina

Carolina Urologic Research Center, Myrtle Beach, South Carolina

Site US10003, Myrtle Beach, South Carolina

Site US10041, Nashville, Tennessee

Site US10010, Dallas, Texas

Site US10034, Houston, Texas

Site US10043, Houston, Texas

Site US10014, Norfolk, Virginia

Site US10015, Virginia Beach, Virginia

Virginia Mason Medical Center, Seattle, Washington

Site US10038, Seattle, Washington

Site US10021, Madison, Wisconsin

Site AR54005, Buenos Aires, Caba

Site AR54007, Rosario, Santa Fé

Site AR54008, Buenos Aires, Not set

Site AR54003, Cordorba, Not set

Site AR54006, San Miguel de Tucuman, Not set

Site AR54002, Tucuman, Not set

Site AU61014, Albury, New South Wales

Site AU61001, Tweed Heads, New South Wales

Site AU61012, Wahroonga, New South Wales

Site AU61017, Wahroonga, New South Wales

Site AU61006, Ashford, Not set

Site AU61019, Ballarat, Not set

Site AU61007, East Bentleigh, Not set

Site AU61009, Malvern, Not set

Site AU61021, Parkville, Not set

Site AU61008, South Brisbane, Not set

Site AU61016, St Albans, Not set

Site AU61004, Westmead, Not set

Site AT43001, Vienna, Not set

Site BE32002, Kortrijk, West-Vlaanderen

Site BE32009, Anderlecht, Not set

Site BE32004, Brussels, Not set

Site BE32005, Gent, Not set

Site BE32011, Gent, Not set

Site BE32007, Hasselt, Not set

Site BE32008, Leuven, Not set

Site BE32001, Liege, Not set

Site BE32003, Turnhout, Not set

Site BR55007, Porto Alegre, RIO Grande DO SUL

Site BR55009, Bahia, Not set

Site BR55008, Campinas, Not set

Site BR55004, Ijuí, Not set

Site BR55011, Jau, Not set

Site BR55002, Rio Grande Do Sul, Not set

Site BR55010, Santo Andre, Not set

Site CA15003, Kingston, Ontario

Site CA15021, Toronto, Ontario

Site CA15001, Granby, Quebec

Site CA15019, Abbotsford, Not set

Site CA15020, Greenville, Not set

Site CA15011, Montreal, Not set

Site CA15017, Oakville, Not set

Site CA15022, Quebec, Not set

Site CL56007, Santiago, RM

Site CL56005, Santiago, RM

Site CL56006, Vina Del Mar, Valparaiso

Site CL56004, IX Region, Not set

Site CL56002, Santiago, Not set

Site CL56001, Vina del Mar, Not set

Site CN86003, Hubei, Not set

Site CN86010, Hunan, Not set

Site CN86005, Nanjing, Not set

Site CZ42004, Olomouc, Not set

Site CZ42002, Olomouc, Not set

Site CZ42003, Praha 2, Not set

Site CZ42001, Praha 6, Not set

Site DK45002, Aalborg, Nordjylland

Site DK45003, Aarhus, Not set

Site DK45001, Copenhagen, Not set

Site DK45004, Herlev, Not set

Site DK45006, Vejle, Not set

Site FL35802, Tampere, Not set

Site FL35805, Turku, Not set

Site FR33021, Bordeaux Cedex, Not set

Site FR33008, La Roche sur Yon, Not set

Site FR33010, Lille, Not set

Site FR33002, Lyon Cedex 3, Not set

Site FR33020, Montpellier Cedex, Not set

Site FR33006, Nimes, Not set

Site FR33003, Paris, Not set

Site FR33017, Paris, Not set

Site FR33001, Saint Herblain, Not set

Site FR33019, Strasbourg, Not set

Site FR33022, Strasbourg, Not set

Site FR33004, Villejuif, Not set

Site GE99501, Tbilisi, Not set

Site DE49004, Nürtingen, Baden-Württemberg

Site DE49007, Waldshut-Tiengen, Baden-Württemberg

Site DE49006, Mannheim, DE

Site DE49001, Duisburg, NRW

Site DE49010, Bonn, Not set

Site DE49003, Hamburg, Not set

Site DE49013, Hamburg, Not set

Site HK85202, Hong Kong, Not set

Site IL97206, Haifa, Not set

Site IL97205, Jerusalem, Not set

Site IL97202, Peth Tikva, Not set

Site IL97204, Ramat-Gan, Not set

Site IL97203, Tzrifin Beer Yakov, Not set

Site IT39008, Faenza (RA), Emilia Romagna

Site IT39001, Arezzo, Not set

Site IT39011, Candiolo, Not set

Site IT39004, Cremona, Not set

Site IT39002, Forli, Not set

Site IT39005, Roma, Not set

Site IT39009, Toscana, Not set

Site IT39006, Trento, Not set

Toho University Sakura Medical Center, Sakura-shi, Chiba

Kyushu University Hospital, Higashi-ku, Fukuoka

Gunma University Hospital, Maebashi-shi, Gunma

Kagawa University Hospital, Kida-gun, Kagawa

Yokohama City University Medical Center, Yokohama, Kanagawa

Kindai University Hospital, Sayama, Osaka

Nippon Medical School Hospital, Bunkyo-ku, Tokyo

The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koutou-ku, Tokyo

Yamaguchi University Hospital, Ube, Yamaguchi

Chiba cancer center, Chiba, Not set

Harasanshin hospital, Fukuoka, Not set

Kyoto University hospital, Kyoto, Not set

Niigata University Medical and Dental Hospital, Niigata, Not set

Osaka Metropolitan University Hospital, Osaka, Not set

Site KR82008, Busan, Not set

Site KR82012, Seongnam-si, Not set

Site KR82005, Seongnam-si, Not set

Site KR82009, Seoul, Not set

Site KR82007, Seoul, Not set

Site KR82011, Seoul, Not set

Site KR82001, Seoul, Not set

Site KR82002, Seoul, Not set

Site KR82003, Seoul, Not set

Site KR82004, Seoul, Not set

Site MY60001, Kuching, Not set

Site MD37301, Chisinau, Not set

Site NL31010, Amsterdam, Not set

Site NL31009, Den Helder, Not set

Site NL31004, Maastricht, Not set

Site NL31011, Rotterdam, Not set

Site NZ64002, Auckland, Not set

Site NZ64005, Dunedin, Not set

Site NZ64001, Hamilton, Not set

Site NO47001, Stavanger, Not set

Site PL48002, Gdansk, Not set

Site PL48001, Myslowice, Not set

Site PL48004, Pozman, Not set

Site PL48005, Slupsk, Not set

Site PL48003, Wrocław, Not set

Site RO40003, Bucuresti, Not set

Site RO40001, Cluj, Not set

Site RO40004, Cluj, Not set

Site RU70008, Ivanovo, Not set

Site RU70001, Moscow, Not set

Site RU70005, Omsk, Not set

Site RU70009, St. Petersburg, Not set

Site RU70003, St. Petersburg, Not set

Site RU70006, St. Petersburg, Not set

Site RS38102, Belgrade, Not set

Site RS38101, Belgrade, Not set

Site SK10223, Bratislava, Not set

Site SK42109, Kosice, Not set

Site SK42106, Kosice, Not set

Site SK42105, Nitra, Not set

Site SK42103, Presov, Not set

Site SK42108, Trencin, Not set

Site SK42107, Zilina, Not set

Site ZA27001, George, Not set

Site ES34007, Barcelona, Not set

Site ES34003, Barcelona, Not set

Site ES34004, Barcelona, Not set

Site ES34011, Gerona, Not set

Site ES34012, Madrid, Not set

Site ES34001, Madrid, Not set

Site ES34008, Madrid, Not set

Site ES34005, Pamplona, Not set

Site ES34014, Salamanca, Not set

Site ES34010, Santiago de Compostela, Not set

Site SE46001, Göteborg, Not set

Site SE46003, Umeå, Not set

Site TW88607, Gueishan, Not set

Site TW88603, Kaohsiung, Not set

Site TW88601, Kaohsiung, Not set

Site TW88602, Taichung, Not set

Site TW88606, Taipei, Not set

Site TH66001, Hat Yai, Songkla

Site TH66002, Bangkok, Not set

Site TR90002, Besevler, Ankara

Site GB44009, Bebington, Not set

Site GB44003, Belfast, Not set

Site GB44004, Bristol, Not set

Site GB44014, Cambridge, Not set

Site GB44005, Cardiff, Not set

Site GB44002, Glasgow, Not set

Site GB44006, London, Not set

Site GB44007, Manchester, Not set

Site GB44008, Northwood, Not set

Site GB44016, Nottingham, Not set

Site GB44001, Sutton, Not set

Conditions: Prostate Cancer

Learn More ›

Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)

NCT02861573

Recruiting

The purpose of this study is to assess the safety and efficacy of pembrolizumab (MK-3475) combination therapy in participants with metastatic castration resistant prostate cancer (mCRPC). There will be ten cohorts in this study: Cohort A will receive pembrolizumab + olaparib, Cohort B will receive pembrolizumab + docetaxel + prednisone, Cohort C will receive pembrolizumab + enzalutamide, Cohort D will receive pembrolizumab + abiraterone + prednisone Cohort E will receive pembrolizumab+lenvatinib... Read More

Gender:

MALE

Ages:

18 years and above

Trial Updated:

07/31/2025

Locations: Call for Information (Investigational Site 0005), Los Angeles, California +26 locations

Call for Information (Investigational Site 0005), Los Angeles, California

Call for Information (Investigational Site 2041), Aurora, Colorado

Call for Information (Investigational Site 2083), Baltimore, Maryland

Call for Information (Investigational Site 2091), Cleveland, Ohio

Call for Information (Investigational Site 2027), Portland, Oregon

Call for Information (Investigational Site 2094), Portland, Oregon

Call for Information (Investigational Site 0008), Pittsburgh, Pennsylvania

Call for Information (Investigational Site 2065), Charleston, South Carolina

Call for Information (Investigational Site 0019), Myrtle Beach, South Carolina

Call for Information (Investigational Site 0016), Seattle, Washington

MSD Australia, North Ryde, Not set

Merck Canada, Kirkland, Quebec

MSD Denmark, Glostrup, Not set

MSD Finland Oy, Espoo, Not set

MSD France, Paris, Not set

MSD Sharp & Dohme GmbH, München, Not set

MSD Ireland (Human Health) Ltd., Dublin, Not set

MSD Italia S.r.l., Rome, Not set

MSD Comercializadora, S. de R.L. de C.V., Mexico City, Not set

Merck Sharp & Dohme BV, Haarlem, Not set

Merck Sharp & Dohme (New Zealand) Ltd.,, Auckland, Not set

MSD Polska Sp. Z o.o., Warsaw, Not set

Merck Sharp and Dohme de Espana S.A., Madrid, Not set

MSD Sweden, Stockholm, Not set

Merck Sharp & Dohme (I.A.) Corp., Taipei, Not set

Merck Sharp & Dohme Ilaclari Ltd. Sti, Istanbul, Not set

Merck Sharp & Dohme Ltd., London, Not set

Conditions: Metastatic Castration-Resistant Prostate Cancer

Learn More ›

Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute)

NCT06691984

Recruiting

The main objective of the study is to compare overall survival in participants receiving xaluritamig versus investigator's choice (cabazitaxel or second androgen receptor-directed therapy \[ARDT\]).

Gender:

MALE

Ages:

18 years and above

Trial Updated:

07/31/2025

Locations: City of Hope National Medical Center, Duarte, California +121 locations

City of Hope National Medical Center, Duarte, California

Providence Saint Jude Medical Center, Fullerton, California

University of California Irvine, Irvine, California

AdventHealth Orlando, Orlando, Florida

Norton Cancer Institute, Louisville, Kentucky

Massachusetts General Hospital, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

University of Minnesota, Minneapolis, Minnesota

Washington University, Saint Louis, Missouri

Sanford Roger Maris Cancer Center, Fargo, North Dakota

Cleveland Clinic Foundation, Cleveland, Ohio

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

Sanford Oncology Clinic and Pharmacy, Sioux Falls, South Dakota

Sarah Cannon Research Institute, Nashville, Tennessee

Tennessee Oncology PLLC, Nashville, Tennessee

University of Texas MD Anderson Cancer Center, Houston, Texas

Virginia Oncology Associates, Norfolk, Virginia

Swedish Medical Center, Seattle, Washington

University of Wisconsin Carbone Cancer Center, Madison, Wisconsin

Chris OBrien Lifehouse, Camperdown, New South Wales

Macquarie University, North Ryde, New South Wales

Princess Alexandra Hospital, Woolloongabba, Queensland

Monash Medical Centre, Clayton, Victoria

The Alfred Hospital, Melbourne, Victoria

Fiona Stanley Hospital, Murdoch, Western Australia

Ordensklinikum Linz Elisabethinen, Linz, Not set

Landeskrankenhaus Salzburg, Salzburg, Not set

Universitaetsklinikum Sankt Poelten, Sankt Poelten, Not set

Krankenhaus der Barmherzigen Brueder Wien, Wien, Not set

Universitaetsklinikum Allgemeines Krankenhaus Wien, Wien, Not set

Universite Catholique de Louvain Cliniques Universitaires Saint Luc, Bruxelles, Not set

Universitair Ziekenhuis Gent, Gent, Not set

Algemeen Ziekenhuis Groeninge - Campus Kennedylaan, Kortrijk, Not set

Centre Hospitalier Universitaire de Liege - Sart Tilman, Liège, Not set

BC Cancer Vancouver, Vancouver, British Columbia

Princess Margaret Cancer Centre, Toronto, Ontario

Sir Mortimer B Davis - Jewish General Hospital, Montreal, Quebec

CHU de Quebec-Universite Laval, Quebec, Not set

Aarhus University Hospital, Aarhus N, Not set

Vejle Sygehus, Vejle, Not set

Centre Hospitalier Universitaire de Grenoble - Hopital Nord Michallon, La Tronche, Not set

Clinique Victor Hugo - Centre Jean Bernard, Le Mans, Not set

Centre Antoine Lacassagne, Nice cedex 2, Not set

Institut Universitaire du Cancer Toulouse Oncopole, Toulouse cedex 9, Not set

Gustave Roussy, Villejuif Cedex, Not set

Charite - Universitaetsmedizin Berlin, Campus Mitte, Berlin, Not set

Universitaetsklinikum Dresden, Dresden, Not set

Universitaetsklinikum Essen, Essen, Not set

Universitaetsklinikum Hamburg Eppendorf, Hamburg, Not set

Universitaetsklinikum Heidelberg, Heidelberg, Not set

Universitaetsklinikum Jena, Jena, Not set

Universitaetsklinikum Schleswig-Holstein - Luebeck, Luebeck, Not set

Klinikum rechts der Isar der TUM, Muenchen, Not set

Universitaetsklinikum Muenster, Muenster, Not set

Universitaetsklinikum Wuerzburg, Wuerzburg, Not set

Alexandra Hospital, Athens, Not set

Athens Medical Center S.A - Iatriko Amarousiou, Athens, Not set

Metropolitan General, Athens, Not set

Metropolitan Hospital, Athens, Not set

Saint Luke Hospital, Thessaloniki, Not set

European Interbalkan Medical Center, Thessaloniki, Not set

Queen Mary Hospital, The University of Hong Kong, Hong Kong, Not set

Azienda Ospedaliero Universitaria Ospedali Riuniti di Foggia, Foggia, Not set

Ospedale Sacro Cuore di Gesù Azienda Sanitaria Locale di Lecce, Gallipoli, Not set

Ospedale Policlinico San Martino IRCCS, Genova, Not set

IRCCS Ospedale San Raffaele, Milano, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Not set

Ospedale Santa Chiara "Azienda Provinciale per i Servizi Sanitari Provincia Autonoma di Trento", Trento, Not set

Nagoya University Hospital, Nagoya-shi, Aichi

National Hospital Organization Shikoku Cancer Center, Matsuyama-shi, Ehime

National Hospital Organization Hokkaido Cancer Center, Sapporo-shi, Hokkaido

Kanazawa University Hospital, Kanazawa-shi, Ishikawa

Yokohama City University Medical Center, Yokohama-shi, Kanagawa

Osaka International Cancer Institute, Osaka-shi, Osaka

The University of Osaka Hospital, Suita-shi, Osaka

Nippon Medical School Hospital, Bunkyo-ku, Tokyo

The Cancer institute Hospital of Japanese Foundation for Cancer Research, Koto-ku, Tokyo

Chungnam National University Hospital, Daejeon, Not set

National Cancer Center, Goyang-si, Gyeonggi-do, Not set

Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Asan Medical Center, Seoul, Not set

Reinier de Graaf Gasthuis, Delft, Not set

Universitair Medisch Centrum Groningen, Groningen, Not set

Radboud Universitair Medisch Centrum, Nijmegen, Not set

SPZOZ Szpital Uniwersytecki w Krakowie, Krakow, Not set

National University Hospital, Singapore, Not set

National Cancer Centre Singapore, Singapore, Not set

Tan Tock Seng Hospital, Singapore, Not set

Hospital Regional Universitario de Malaga, Malaga, Andalucía

Hospital Universitario Virgen del Rocio, Sevilla, Andalucía

Hospital Universitari Vall d Hebron, Barcelona, Cataluña

Hospital Clinic i Provincial de Barcelona, Barcelona, Cataluña

Hospital de la Santa Creu i Sant Pau, Barcelona, Cataluña

Instituto Valenciano de Oncologia, Castellon, Comunidad Valenciana

Clinica Universidad de Navarra, Pamplona, Navarra

Institut Catala d Oncologia Hospitalet Hospital Duran i Reynals, Barcelona, Not set

Hospital Clinico San Carlos, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Sahlgrenska Universitetssjukhuset, Goteborg, Not set

Skanes Universitetssjukhus, Lund, Not set

Karolinska Universitetssjukhuset, Stockholm, Not set

Norrlands Universitetssjukhus, Umea, Not set

Istituto Oncologico della Svizzera Italiana, Bellinzona, Not set

Inselspital Bern, Bern, Not set

Kantonsspital Graubuenden, Chur, Not set

Centre Hospitalier Universitaire Vaudois, Lausanne, Not set

Kantonsspital Sankt Gallen, Sankt Gallen, Not set

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set

Taichung Veterans General Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation, Taoyuan, Not set

Izmir Medical Point Hastanesi, Izmir, Not set

Beatson West of Scotland Cancer Centre, Glasgow, Not set

University College London Hospital, London, Not set

Guys Hospital, London, Not set

Sarah Cannon Research Institute UK, London, Not set

Royal Marsden Hospital, Sutton, Not set

Conditions: Metastatic Castration-resistant Prostate Cancer

Learn More ›

Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations (PROSPERO).

NCT05742802

Recruiting

Subjects who completed either OBERON or TITANIA will be offered the opportunity to consent for this Multicentre, Double-blind, Randomised, Placebo controlled, Parallel Group, Phase 3, extension study to evaluate the safety and efficacy of Tozorakimab in adult participants with symptomatic COPD.

Gender:

ALL

Ages:

Between 40 years and 130 years

Trial Updated:

07/31/2025

Locations: Research Site, Huntsville, Alabama +390 locations

Research Site, Huntsville, Alabama

Research Site, Sheffield, Alabama

Research Site, Tempe, Arizona

Research Site, Bakersfield, California

Research Site, Lincoln, California

Research Site, Newport Beach, California

Research Site, Northridge, California

Research Site, Boynton Beach, Florida

Research Site, Cape Coral, Florida

Research Site, Ormond Beach, Florida

Research Site, Pensacola, Florida

Research Site, Plantation, Florida

Research Site, Tampa, Florida

Research Site, Winter Park, Florida

Research Site, Evergreen Park, Illinois

Research Site, Normal, Illinois

Research Site, Greenwood, Indiana

Research Site, Iowa City, Iowa

Research Site, Kansas City, Kansas

Research Site, Bowling Green, Kentucky

Research Site, Baton Rouge, Louisiana

Research Site, Zachary, Louisiana

Research Site, Baltimore, Maryland

Research Site, White Marsh, Maryland

Research Site, North Dartmouth, Massachusetts

Research Site, Farmington Hills, Michigan

Research Site, Grand Rapids, Michigan

Research Site, Rochester, Minnesota

Research Site, Saint Louis, Missouri

Research Site, Missoula, Montana

Research Site, Buffalo, New York

Research Site, New York, New York

Research Site, Durham, North Carolina

Research Site, Gastonia, North Carolina

Research Site, Fargo, North Dakota

Research Site, Toledo, Ohio

Research Site, Tulsa, Oklahoma

Research Site, DuBois, Pennsylvania

Research Site, Philadelphia, Pennsylvania

Research Site, Pittsburgh, Pennsylvania

Research Site, Sayre, Pennsylvania

Research Site, Rock Hill, South Carolina

Research Site, Franklin, Tennessee

Research Site, Amarillo, Texas

Research Site, Boerne, Texas

Research Site, Fort Worth, Texas

Research Site, Houston, Texas

Research Site, Kingwood, Texas

Research Site, McKinney, Texas

Research Site, Tomball, Texas

Research Site, Webster, Texas

Research Site, Colchester, Vermont

Research Site, Williamsburg, Virginia

Research Site, Cudahy, Wisconsin

Research Site, Buenos Aires, Not set

Research Site, Caba, Not set

Research Site, Córdoba, Not set

Research Site, Florencio Varela, Not set

Research Site, Mar del Plata, Not set

Research Site, Mendoza, Not set

Research Site, Quilmes, Not set

Research Site, San Fernando, Not set

Research Site, San Miguel de Tucumán, Not set

Research Site, Campbelltown, Not set

Research Site, Frankstown, Not set

Research Site, Macquarie University, Not set

Research Site, Melbourne, Not set

Research Site, Nedlands, Not set

Research Site, Southport, Not set

Research Site, Spearwood, Not set

Research Site, Wollongong, Not set

Research Site, Woodville South, Not set

Research Site, Bruxelles, Not set

Research Site, Gent, Not set

Research Site, Leuven, Not set

Research Site, Liege, Not set

Research Site, Namur, Not set

Research Site, Blumenau, Not set

Research Site, Botucatu, Not set

Research Site, Brasilia, Not set

Research Site, Curitiba, Not set

Research Site, Porto Alegre, Not set

Research Site, Rio de Janeiro, Not set

Research Site, Sao Bernardo do Campo, Not set

Research Site, São Paulo, Not set

Research Site, Dupnitsa, Not set

Research Site, Kozloduy, Not set

Research Site, Lovech, Not set

Research Site, Petrich, Not set

Research Site, Pleven, Not set

Research Site, Ruse, Not set

Research Site, Sliven, Not set

Research Site, Sofia, Not set

Research Site, Troyan, Not set

Research Site, Vratsa, Not set

Research Site, Edmonton, Alberta

Research Site, Sherwood Park, Alberta

Research Site, Ajax, Ontario

Research Site, Guelph, Ontario

Research Site, Winchester, Ontario

Research Site, Montreal, Quebec

Research Site, Quebec, Not set

Research Site, Chile, Not set

Research Site, Curico, Not set

Research Site, Santiago, Not set

Research Site, Talca, Not set

Research Site, Baotou, Not set

Research Site, Beijing, Not set

Research Site, Changchun, Not set

Research Site, Changde, Not set

Research Site, Changsha, Not set

Research Site, Chengdu, Not set

Research Site, Chongqing, Not set

Research Site, Guangzhou, Not set

Research Site, Haikou, Not set

Research Site, Hangzhou, Not set

Research Site, Hefei, Not set

Research Site, Hohhot, Not set

Research Site, Kunming, Not set

Research Site, Linhai, Not set

Research Site, Nanchang, Not set

Research Site, Nanjing, Not set

Research Site, Ningbo, Not set

Research Site, Shanghai, Not set

Research Site, Shenyang, Not set

Research Site, Shenzhen, Not set

Research Site, Shijiazhuang, Not set

Research Site, Suzhou, Not set

Research Site, Taiyuan, Not set

Research Site, Tianjin, Not set

Research Site, Wuhan, Not set

Research Site, Wuxi, Not set

Research Site, Xiamen, Not set

Research Site, Xuzhou, Not set

Research Site, Yangzhou, Not set

Research Site, Yinchuan, Not set

Research Site, Zhanjiang, Not set

Research Site, Zunyi, Not set

Research Site, Barranquilla, Not set

Research Site, Ibague, Not set

Research Site, Rionegro, Not set

Research Site, Zipaquira, Not set

Research Site, Brno, Not set

Research Site, Broumov, Not set

Research Site, Jihlava, Not set

Research Site, Jindrichuv Hradec, Not set

Research Site, Liberec 1, Not set

Research Site, Olomouc, Not set

Research Site, Rokycany, Not set

Research Site, Copenhagen, Not set

Research Site, Hvidovre, Not set

Research Site, Naestved, Not set

Research Site, Roskilde, Not set

Research Site, Vejle, Not set

Research Site, Ålborg, Not set

Research Site, Helsinki, Not set

Research Site, Hämeenlinna, Not set

Research Site, Kuopio, Not set

Research Site, Tampere, Not set

Research Site, Turku, Not set

Research Site, Bordeaux, Not set

Research Site, Brest Cedex, Not set

Research Site, Dijon, Not set

Research Site, La Tronche, Not set

Research Site, Limoges, Not set

Research Site, Lyon Cedex 04, Not set

Research Site, MARSEILLE cedex 15, Not set

Research Site, Montpellier Cedex 5, Not set

Research Site, Nantes, Not set

Research Site, Toulouse, Not set

Research Site, Ahrensburg, Not set

Research Site, Bamberg, Not set

Research Site, Berlin, Not set

Research Site, Darmstadt, Not set

Research Site, Halle, Not set

Research Site, Köln, Not set

Research Site, Marburg, Not set

Research Site, München-Pasing, Not set

Research Site, München, Not set

Research Site, Peine, Not set

Research Site, Alexandroupolis, Not set

Research Site, Athens, Not set

Research Site, Exohi Thessaloniki, Not set

Research Site, Ioannina, Not set

Research Site, Patras, Not set

Research Site, Thessaloniki, Not set

Research Site, Budapest, Not set

Research Site, Debrecen, Not set

Research Site, Edelény, Not set

Research Site, Encs, Not set

Research Site, Gyöngyös, Not set

Research Site, Mosonmagyaróvár, Not set

Research Site, Nyíregyháza-Sóstóhegy, Not set

Research Site, Százhalombatta, Not set

Research Site, Belagavi, Not set

Research Site, Coimbatore, Not set

Research Site, Dehradun, Not set

Research Site, Jaipur, Not set

Research Site, Nagpur, Not set

Research Site, Nashik, Not set

Research Site, New Delhi, Not set

Research Site, Thane, Not set

Research Site, Ashkelon, Not set

Research Site, Beer Sheva, Not set

Research Site, Jerusalem, Not set

Research Site, Kfar-Saba, Not set

Research Site, Rehovot, Not set

Research Site, Tel Aviv, Not set

Research Site, Bari, Not set

Research Site, Carrara, Not set

Research Site, Milano, Not set

Research Site, Napoli, Not set

Research Site, Roma, Not set

Research Site, Salerno, Not set

Research Site, Sassari, Not set

Research Site, Statte, Not set

Research Site, Telese Terme, Not set

Research Site, Tradate, Not set

Research Site, Vercelli, Not set

Research Site, Verona, Not set

Research Site, Asahikawa-shi, Not set

Research Site, Chuo-ku, Not set

Research Site, Fujieda-shi, Not set

Research Site, Fukuoka-shi, Not set

Research Site, Hamamatsu-shi, Not set

Research Site, Hiroshima-shi, Not set

Research Site, Iizuka-shi, Not set

Research Site, Itabashi-ku, Not set

Research Site, Iwata-shi, Not set

Research Site, Joyo-shi, Not set

Research Site, Kanazawa-shi, Not set

Research Site, Kawachinagano-shi, Not set

Research Site, Kobe-shi, Not set

Research Site, Kokubunji-shi, Not set

Research Site, Matsusaka-shi, Not set

Research Site, Mizunami-shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Obihiro, Not set

Research Site, Okayama, Not set

Research Site, Osaka-shi, Not set

Research Site, Sakai-shi, Not set

Research Site, Shinjuku-ku, Not set

Research Site, Shizuoka-shi, Not set

Research Site, Toshima-ku, Not set

Research Site, Toyonaka-shi, Not set

Research Site, Yokohama-shi, Not set

Research Site, Daegu, Not set

Research Site, Incheon, Not set

Research Site, Jeonju, Not set

Research Site, Seoul, Not set

Research Site, Benito Juarez, Not set

Research Site, Chihuahua, Not set

Research Site, Guadalajara, Not set

Research Site, Mexico, Not set

Research Site, Monterrey, Not set

Research Site, Morelia, Not set

Research Site, Mérida, Not set

Research Site, Oaxaca, Not set

Research Site, Veracruz, Not set

Research Site, Eindhoven, Not set

Research Site, Groningen, Not set

Research Site, Harderwijk, Not set

Research Site, Heerlen, Not set

Research Site, Zutphen, Not set

Research Site, Zwolle, Not set

Research Site, Bergen, Not set

Research Site, Bodø, Not set

Research Site, Lørenskog, Not set

Research Site, Oslo, Not set

Research Site, Tønsberg, Not set

Research Site, Godoy Cruz, Not set

Research Site, Lima, Not set

Research Site, Piura, Not set

Research Site, Baguio, Not set

Research Site, Cebu City, Not set

Research Site, Iloilo City, Not set

Research Site, Manila, Not set

Research Site, Białystok, Not set

Research Site, Bydgoszcz, Not set

Research Site, Katowice, Not set

Research Site, Krakow, Not set

Research Site, Lublin, Not set

Research Site, Ostrowiec Świętokrzyski, Not set

Research Site, Ostróda, Not set

Research Site, Poznań, Not set

Research Site, Rzeszów, Not set

Research Site, Sosnowiec, Not set

Research Site, Wroclaw, Not set

Research Site, Wrocław, Not set

Research Site, Guimaraes, Not set

Research Site, Lisboa, Not set

Research Site, Matosinhos, Not set

Research Site, Vila Franca de Xira, Not set

Research Site, Vila Nova de Gaia, Not set

Research Site, Brasov, Not set

Research Site, Bucharest, Not set

Research Site, Cluj-Napoca, Not set

Research Site, Constanta, Not set

Research Site, Timisoara, Not set

Research Site, Galdakao, Not set

Research Site, Madrid, Not set

Research Site, Merida, Not set

Research Site, Málaga, Not set

Research Site, Pozuelo de Alarcon, Not set

Research Site, Santander, Not set

Research Site, Valencia, Not set

Research Site, Zaragoza, Not set

Research Site, Göteborg, Not set

Research Site, Lund, Not set

Research Site, Malmö, Not set

Research Site, Stockholm, Not set

Research Site, Hsinchu, Not set

Research Site, Kaohsiung, Not set

Research Site, Taichung, Not set

Research Site, Taipei City, Not set

Research Site, Taipei, Not set

Research Site, Taoyuan, Not set

Research Site, Yunlin, Not set

Research Site, Bang Kra So, Not set

Research Site, Bangkok, Not set

Research Site, Hat Yai, Not set

Research Site, Khon Kaen, Not set

Research Site, Muang,, Not set

Research Site, Muang, Not set

Research Site, Mueang, Not set

Research Site, Nakhon Ratchasima, Not set

Research Site, Ankara, Not set

Research Site, Istanbul, Not set

Research Site, Mersin, Not set

Research Site, Bradford, Not set

Research Site, Corby, Not set

Research Site, Enfield, Not set

Research Site, High Wycombe, Not set

Research Site, Northwood, Not set

Research Site, Preston, Not set

Research Site, Shipley, Not set

Research Site, Hanoi, Not set

Research Site, Ho Chi Minh, Not set

Conditions: Chronic Obstructive Pulmonary Disease (COPD)

Learn More ›

A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2)

NCT05552976

Recruiting

The purpose of the study is to compare Mezigdomide (CC-92480/BMS-986348) with carfilzomib and dexamethasone (MeziKD) against carfilzomib and dexamethasone (Kd) in the treatment of RRMM: SUCCESSOR-2.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/31/2025

Locations: Local Institution - 0046, Mobile, Alabama +216 locations

Local Institution - 0046, Mobile, Alabama

Local Institution - 0005, Cerritos, California

Local Institution - 0190, Irvine, California

Local Institution - 0187, Los Angeles, California

Local Institution - 0344, Santa Rosa, California

Local Institution - 0339, Stockton, California

Local Institution - 0279, Newark, Delaware

Local Institution - 0341, Fort Myers, Florida

Local Institution - 0342, Saint Petersburg, Florida

Local Institution - 0340, West Palm Beach, Florida

Local Institution - 0348, Atlanta, Georgia

Local Institution - 0291, Atlanta, Georgia

Saint Alphonsus Regional Medical Center, Boise, Idaho

Local Institution - 0289, Annapolis, Maryland

Local Institution - 0204, Boston, Massachusetts

Local Institution - 0346, Minneapolis, Minnesota

Local Institution - 0222, Little Silver, New Jersey

Local Institution - 0199, Bronx, New York

University of North Carolina Medical Center, Chapel Hill, North Carolina

Local Institution - 0322, Cleveland, Ohio

Local Institution - 0172, Columbus, Ohio

Local Institution - 0321, Providence, Rhode Island

Charleston Oncology, P.A., Charleston, South Carolina

Local Institution - 0338, Greer, South Carolina

Local Institution - 0349, Chattanooga, Tennessee

Local Institution - 0323, Nashville, Tennessee

Local Institution - 0337, Fort Worth, Texas

Local Institution - 0328, Houston, Texas

Local Institution - 0044, Houston, Texas

Local Institution - 0195, Temple, Texas

Local Institution - 0345, Norfolk, Virginia

Local Institution - 0343, Roanoke, Virginia

Local Institution - 0006, Tacoma, Washington

Local Institution - 0347, Vancouver, Washington

Local Institution - 0243, Morgantown, West Virginia

Local Institution - 0336, Marshfield, Wisconsin

Local Institution - 0008, Ciudad Autónoma de Buenos Aires, Buenos Aires

Local Institution - 0079, ABB, Ciudad Autónoma De Buenos Aires

Local Institution - 0182, Rosario, Santa Fe

Local Institution - 0319, San Miguel de Tucumán, Tucumán

Local Institution - 0150, Buenos Aires, Not set

Local Institution - 0151, Córdoba, Not set

Local Institution - 0077, Camperdown, New South Wales

Local Institution - 0160, Gosford, New South Wales

Local Institution - 0263, Port Macquarie, New South Wales

Local Institution - 0078, St Leonards, New South Wales

Local Institution - 0026, Sydney, New South Wales

Local Institution - 0024, Adelaide, South Australia

Local Institution - 0229, Hobart, Tasmania

Local Institution - 0131, Bendigo, Victoria

Local Institution - 0224, East Melbourne, Victoria

Local Institution - 0127, Heidelberg, Victoria

Local Institution - 0025, Melbourne, Victoria

Local Institution - 0266, Vienna, Wien

Local Institution - 0020, Linz, Not set

Local Institution - 0017, Wien, Not set

Local Institution - 0119, Wien, Not set

Local Institution - 0121, Salvador, Bahia

Local Institution - 0076, Porto Alegre, Rio Grande Do Sul

Local Institution - 0085, Sao Paulo, São Paulo

Local Institution - 0075, Rio de Janeiro, Not set

Local Institution - 0086, Rio de Janeiro, Not set

Local Institution - 0073, São Paulo, Not set

University Multiprofile Hospital for Active Treatment "Sveti Georgi" EAD, Plovdiv, Not set

Acibadem City Clinic University Multiprofile Hospital for Active Treatment Tokuda EAD, Sofia, Not set

UMHAT 'Sveti Ivan Rilsky', Sofia, Not set

Local Institution - 0183, Halifax, Nova Scotia

Local Institution - 0275, London, Ontario

Local Institution - 0184, Toronto, Ontario

Local Institution - 0186, Montreal, Quebec

Local Institution - 0318, Hefei, Anhui

Local Institution - 0057, Beijing City, Beijing

Local Institution - 0061, Beijing, Beijing

Local Institution - 0056, Beijing, Beijing

Local Institution - 0123, Fuzhou, Fujian

Local Institution - 0138, Guangzhou, Guangdong

Local Institution - 0315, Guangzhou, Guangdong

Local Institution - 0051, Zhengzhou, Henan

Local Institution - 0066, Wuhan, Hubei

Local Institution - 0054, Wuhan, Hubei

Local Institution - 0071, Changsha, Hunan

Local Institution - 0103, Changsha, Hunan

Local Institution - 0180, Nanjing, Jiangsu

Local Institution - 0111, Nantong, Jiangsu

Local Institution - 0104, Suzhou, Jiangsu

Local Institution - 0069, Wuxi, Jiangsu

Local Institution - 0095, Nanchang, Jiangxi

Local Institution - 0052, Changchun, Jilin

Local Institution - 0096, Shenyang, Liaoning

Local Institution - 0176, Shenyang, Liaoning

Local Institution - 0060, Xi'an, Shaanxi

Local Institution - 0072, Jinan, Shandong

Local Institution - 0118, Shanghai, Shanghai

Local Institution - 0317, Shanghai, Shanghai

Local Institution - 0091, Tianjing, Tianjin

Local Institution - 0058, Kunming, Yunnan

Local Institution - 0050, Hangzhou, Zhejiang

Local Institution - 0115, Wenzhou, Zhejiang

Local Institution - 0059, Taiyuan, Not set

Local Institution - 0153, Medellin, Antioquia

Local Institution - 0156, Valledupar, Cesar

Local Institution - 0154, Bogota, Cundinamarca

Local Institution - 0324, Piedecuesta, Santander

Local Institution - 0155, Cali, Not set

Local Institution - 0032, Aarhus, Midtjylland

Local Institution - 0065, Roskilde, Sjælland

Local Institution - 0129, Odense, Syddanmark

Local Institution - 0125, Vejle, Not set

Universitaetsklinikum Ulm, Ulm, Baden-Wurttemberg

Haematologie und Onkologie Muenchen-Pasing, Munich, Bayern

Klinikum Nuernberg Nord, Urologische Klinik, Nürnberg, Bayern

Praxis Onkologie am Raschplatz, Hannover, Niedersachsen

GEFOS Gesellschaft f. onkologische Studien, Dortmund, Nordrhein-Westfalen

Universitaetsklinikum Schleswig-Holstein Campus Kiel, Kiel, Schleswig-Holstein

Universitätsklinikum Jena, Jena, Thüringen

Charite Universitätsmedizin Berlin Campus Benjamin Franklin, Berlin, Not set

Universitaetsklinikum Carl Gustav Carus Dresden, Dresden, Not set

Marien Hospital Düsseldorf, Düsseldorf, Not set

Universitaetsklinikum Heidelberg, Heidelberg, Not set

Local Institution - 0102, Köln, Not set

Universitätsklinikum Leipzig, Leipzig, Not set

Universitaetsklinikum Wuerzburg, Wuerzburg, Not set

Local Institution - 0136, Patras, Achaḯa

Local Institution - 0135, Athens, Attikí

Local Institution - 0134, Thessaloniki, Thessaloníki

Local Institution - 0178, Hksar, Not set

Pécsi Tudományegyetem Klinikai Központ, Pécs, Baranya

Debreceni Egyetem Klinikai Kozpont, Debrecen, Hajdú-Bihar

Szabolcs Szatmár Bereg Vármegyei Oktatókórház, Nyiregyhaza, Szabolcs-Szatmár-Bereg

Semmelweis Egyetem, Budapest, Not set

Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet, Budapest, Not set

Local Institution - 0170, New Delhi, Delhi

Local Institution - 0167, Gurgaon, Haryana

Local Institution - 0161, Bengaluru, Karnataka

Local Institution - 0168, Mumbai, Maharashtra

Local Institution - 0171, Thane, Maharashtra

Local Institution - 0261, Mohali, Punjab

Local Institution - 0174, Chennai, Tamil Nadu

Local Institution - 0165, Hyderabad, Telangana

Local Institution - 0310, Hyderabad, Telangana

Local Institution - 0164, Hyderabad, Telangana

Local Institution - 0230, Chandigarh, Not set

Local Institution - 0264, Holon, HaMerkaz

Local Institution - 0267, Zerifin, HaMerkaz

Local Institution - 0277, Jerusalem, Not set

Local Institution - 0145, Meldola, Emilia-Romagna

Local Institution - 0143, Milano, Lombardia

Local Institution - 0142, Rozzano, Milano

Local Institution - 0189, Bologna, Not set

Local Institution - 0148, Catanzaro, Not set

Local Institution - 0147, Lecce, Not set

Local Institution - 0144, Pisa, Not set

Local Institution - 0146, Udine, Not set

Local Institution - 0269, Nagoya, Aichi

Local Institution - 0214, Kashiwa, Chiba

Local Institution - 0210, Kitakyushu-shi, Fukuoka

Local Institution - 0211, Sapporo, Hokkaido

Local Institution - 0217, Higashiibaraki, Ibaraki

Local Institution - 0300, Kanazawa, Ishikawa

Local Institution - 0209, Shiwa-gun Yahaba-cho, Iwate

Local Institution - 0234, Kamakura, Kanagawa

Local Institution - 0225, Koshigaya, Saitama

Local Institution - 0236, Itabashiku, Tokyo

Local Institution - 0219, Koto-ku, Tokyo

Local Institution - 0303, Chuo, Yamanashi

Local Institution - 0215, Chiba, Not set

Local Institution - 0226, Fukuoka, Not set

Local Institution - 0235, Fukuoka, Not set

Local Institution - 0220, Kumamoto, Not set

University Hospital,Kyoto Prefectural University of Medicine, Kyoto, Not set

Local Institution - 0213, Nagasaki, Not set

Local Institution - 0212, Okayama, Not set

Local Institution - 0301, Osaka, Not set

Local Institution - 0241, Tokyo, Not set

Local Institution - 0218, Tokyo, Not set

Local Institution - 0238, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0239, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0240, Seoul, Seoul-teukbyeolsi [Seoul]

Amphia Ziekenhuis, locatie Breda Molengracht, Breda, Noord-Brabant

Medisch Spectrum Twente, Enschede, Not set

Local Institution - 0049, Bergen, Hordaland

Local Institution - 0112, Stavanger, Rogaland

Local Institution - 0081, Oslo, Not set

Local Institution - 0316, San Juan, Not set

Fundeni Clinical Institute, Bucuresti, București

Local Institution - 0290, Timișoara, Timiș

Sc Onco Card Srl, Brasov, Not set

Affidea Fundeni, București, Not set

Spitalul Clinic Colțea, București, Not set

Spitalul Clinic Județean de Urgență Sibiu, Sibiu, Not set

Local Institution - 0158, Singapore, Central Singapore

Local Institution - 0159, Singapore, Central Singapore

Local Institution - 0126, Badalona, Barcelona [Barcelona]

Local Institution - 0092, Barcelona, Barcelona [Barcelona]

Local Institution - 0038, L'Hospitalet Del Llobregat, Barcelona [Barcelona]

Local Institution - 0200, Madrid, Madrid, Comunidad De

Local Institution - 0108, Majadahonda, Madrid, Comunidad De

Local Institution - 0192, San Cristobal de La laguna, Santa Cruz De Tenerife

Local Institution - 0201, San Cristobal de La laguna, Santa Cruz De Tenerife

Local Institution - 0037, Valencia, Valenciana, Comunitat

Local Institution - 0107, Granada, Not set

Local Institution - 0047, Madrid, Not set

Local Institution - 0105, Málaga, Not set

Local Institution - 0274, Chiayi City, Chiayi

Local Institution - 0177, Kaohsiung Niao Sung Dist, Kaohsiung

Local Institution - 0012, Kaohsiung, Not set

Local Institution - 0001, Taichung, Not set

Local Institution - 0002, Tainan, Not set

Local Institution - 0149, Taipei, Not set

Local Institution - 0162, Taipei, Not set

Local Institution - 0139, Plymouth, Devon

Local Institution - 0067, Cringleford, England

Local Institution - 0196, Glasgow, Glasgow City

Local Institution - 0039, Birmingham, Not set

Local Institution - 0273, Birmingham, Not set

Local Institution - 0080, Leeds, Not set

Local Institution - 0040, Taunton, Not set

Conditions: Relapsed or Refractory Multiple Myeloma

Learn More ›

High Flow Oxygen Therapy After Spinal Cord Injury

NCT06244160

Recruiting

The goal of this feasibility study is to learn about the ability to use a different form of oxygen therapy (known as high flow oxygen therapy) in patients who have a spinal cord injury in the upper back or neck. The main questions it aims to answer are: 1. Is it possible to recruit patients to the study 2. It is possible to follow the protocol in its current format 3. What is the impact on those receiving the intervention. Participants will be randomised to receive either standard care or hig... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/31/2025

Locations: Cardiff and Vale University Health Board, Cardiff, Not set

Conditions: Spinal Cord Injuries, Respiratory Failure

Learn More ›

Randomized Trial of UI-EWD vs. Conventional Endoscopic Therapy for Nonvariceal Upper Gastrointestinal Bleeding

NCT06188585

Recruiting

A prospective, multi-center, noninferiority randomized controlled trial designed to compare the efficacy of UI-EWD (Nexpowder™) hemostatic powder versus conventional endoscopic hemostatic therapy in patients presenting with acute overt gastrointestinal bleeding which is found at endoscopy to be due to one of the following sources: a gastric or duodenal ulcer with active bleeding (spurting or oozing) or a non-bleeding visible vessel; an esophageal, gastric or duodenal tumor with active bleeding o... Read More

Gender:

ALL

Ages:

22 years and above

Trial Updated:

07/31/2025

Locations: University of Alabama, Birmingham, Alabama +14 locations

Conditions: Acute Gastrointestinal Bleeding

Learn More ›

Study of PYX-201 in Solid Tumors

NCT05720117

Recruiting

The primary objectives of this study are to determine the recommended dose(s) of PYX-201 for participants with relapsed/refractory (R/R) solid tumors, and to determine the objective response rate (ORR) in participants treated with PYX-201 as a single agent.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/31/2025

Locations: HonorHealth Research Institute, Scottsdale, Arizona +19 locations

Conditions: Solid Tumor, Advanced Solid Tumor

Learn More ›

REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors)

NCT05973773

Recruiting

The purpose of this study is to evaluate the safety and efficacy of zipalertinib in combination with standard first-line platinum-based chemotherapy compared to chemotherapy alone, in patients with locally advanced or metastatic NSCLC with EGFR ex20ins mutations.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/31/2025

Locations: Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada +130 locations

Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada

Comprehensive Cancer Centers of Nevada - Horizon Ridge Henderson, Henderson, Nevada

Comprehensive Cancer Centers of Nevada - Southeast Henderson - Stephanie, Henderson, Nevada

Comprehensive Cancer Centers of Nevada - Summerlin Medical Center II, Las Vegas, Nevada

Comprehensive Cancer Centers of Nevada - Southwest, Las Vegas, Nevada

Comprehensive Cancer Centers of Nevada - Central Valley - Twain, Las Vegas, Nevada

Comprehensive Cancer Centers of Nevada - Northwest, Las Vegas, Nevada

Gabrail Cancer and Research Center, Canton, Ohio

The Toledo Clinic Cancer Center, Toledo, Ohio

University of Texas MD Anderson Cancer Center, Houston, Texas

Universitair Ziekenhuis Leuven - Campus Gasthuisberg, Leuven, Flemish Brabant

Algemeen Ziekenhuis Maria Middelares, Gent, Oost-Vlaaderen

Algemeen Ziekenhuis Delta - Campus Menen, Menen, West Flanders

Algemeen Ziekenhuis Delta - Campus Rumbeke, Rosières, West-Vlaanderen

Centro Regional Integrado de Oncologia, Fortaleza, Ceará

Hospital São Lucas da PUCRS, Porto Alegre, Rio Grande Do Sul

Hospital Mãe de Deus - Centro Integrado de Oncologia, Porto Alegre, RS

Clínica Neoplasias Litoral, Itajaí, Santa Catatina

Hospital Amaral Carvalho, Jaú, São Paulo

Multi-profile Hospital for Active Treatment Uni Hospital, Panagyurishte, Pazardzhik

University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna-ISUL, Sofia, Not set

BC Cancer Vancouver, Vancouver, British Columbia

William Osler Health System - Brampton Civic Hospital, Brampton, Ontario

Princess Margaret Cancer Centre, Toronto, Ontario

CentroEstudiosClinicosSAGA, Santiago, Region De Santiago

Hospital Clínico Universidad de Chile, Independencia, Santiago

Instituto Oncológico Fundación Arturo López Pérez, Providencia, Santiago

Les Hôpitaux Universitaires de Strasbourg, Strasbourg cedex, Alsace

Hôpital Côte De Nacre, Caen cedex 9, Basse-Normandie

Institut Curie, Paris cedex, Ile-de-France

Centre Hospitalier Universitaire Limoges, Limoges, Limousin

Hôpital Haut-Lévêque, Pessac, Nouvelle-Aquitaine

Centre Hospitalier Le Mans, Le Mans cedex 9, Pays De La Loire

Gustave Roussy, Villejuif, Val-de-Marne

CH Cornouaille Quimper, Quimper, Not set

Hôpital Ambroise-Paré, Boulogne-Billancourt, Île-de-France

Asklepios Klinik Altona, Hamburg, Hamburg (Hansestadt)

Universitätsklinikum Gießen und Marburg - Gießen, Gießen, Hessen

LMU Klinikum - Campus Innenstadt, München, Not set

Universitätsklinikum Regensburg, Regensburg, Not set

General Hospital for Thoracic Diseases Sotiria, Athens, Attica

Metropolitan General, Piraeus, Attica

University General Hospital of Patras, Patra, Peloponnese

Metropolitan Hospital, Peiraias, Pireas

University General Hospital of Larissa, Larissa, Thessaly

BioClinic Thessaloniki, Thessaloniki, Not set

Emek Medical Center, Afula, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

Hadassah University Hospital Ein Kerem, Jerusalem, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

Assuta Hospital - Ramat HaHayal, Tel aviv, Not set

Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST, Meldola, Forli-Cesena

Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST, Meldola, Forlì-Cesena

Istituto Nazionale per la Ricerca sul Cancro, Genova, Genoa

Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele, Milan, Not set

Azienda Ospedaliero - Universitaria di Modena, Modena, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

Azienda Unità Sanitaria Locale della Romagna, Ravenna, Not set

IRCCS Istituto Nazionale Tumori Regina Elena, Roma, Not set

Azienda Ospedaliera Universitaria Integrata Verona, Verona, Not set

Aichi Cancer Center, Nagoya, Aiti [Aichi]

Hirosaki University Hospital, Hirosaki-Shi, Aomori

Kyushu Cancer Center, Fukuoka-shi, Hukuoka

Kitasato University Hospital, Sagamihara, Kanagawa

Kanagawa Cardiovascular and Respiratory Center, Yokohama, Kanagawa

Saiseikai Kumamoto Hospital, Kumamoto-Shi, Kumamoto

Sendai Kousei Hospital, Sendai, Miyagi

Okayama University Hospital, Okayamashi, Okayama

Kansai Medical University Hospital, Hirakata, Osaka

National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai-Shi, Osaka

Cancer Institute Hospital of JFCR, Koto, Tokyo

Keio University Hospital, Shinjuku-Ku, Tokyo

Kanazawa University Hospital, Kanazawa, Not set

Osaka City General Hospital, Osaka, Not set

Osaka Prefectural Hospital Organization - Osaka International Cancer Institute, Osaka, Not set

Seoul National University Bundang Hospital, Seongnam, Gyeonggi-Do

Catholic University of Korea Saint Vincent's Hospital, Suwon-si, Gyeonggi-do

Ajou University Hospital, Suwon-si, Gyeonggi-do

Gyeongsang National University Hospital, Jinju, Gyeongsangnamdo [Kyongsangnam-do]

Inha University Hospital, Incheon, Incheon Gwang'yeogsi [Inch'on-Kwangyokshi]

Korea University Anam Hospital, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi]

Korea University Guro Hospital, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi]

Health Pharma Professional Research S.A. De C.V, Mexico City, Distrito Federal

Antiguo Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jalisco

Actualidad Basada en la Investigación del Cáncer, Guadalajara, Jalisco

Clínica Integral Internacional de Oncología S de RL de CV, Mirador, Puebla

Investigacion Medica Galerias, Aguascalientes, Not set

FAICIC Clínical Research, Veracruz, Not set

Radboud Universitair Medisch Centrum, Nijmegen, Gelderland

Antoni Van Leeuwenhoek Ziekenhuis, Amsterdam, Noord-Holland

Vrije Universiteit Medisch Centrum, Amsterdam, Noord-Holland

The Medical City, Pasig, Metro Manila

St. Luke's Medical Center - Quezon City, Quezon City, Metropolitan Manila

Asian Hospital and Medical Center, Muntinlupa, Not set

Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin, Lubelskie

Instytut MSF, Łódź, Lódzkie

Wielkopolskie Centrum Pulmonologii i Torakochirurgii im. Eugenii i Janusza Zeylandów, Pozna?, Wielkopolskie

Medisprof, Cluj-Napoca, Cluj

Centrul de Oncologie Sf Nectarie, Craiova, Dolj

Oncocenter - Oncologie Clinica, Timişoara, Timis

Clinica SIGMedical, Suceava, Not set

National Cancer Centre Singapore, Singapore, Not set

Icon Cancer Centre - Mount Alvernia, Singapore, Not set

Tan Tock Seng Hospital, Singapore, Not set

Oncocare Cancer Centre, Singapore, Not set

Icon Cancer Centre Mount Elizabeth, Singapore, Not set

Complejo Hospitalario Universitario A Coruña, A Coruña, La Coruña

Clínica Mi Tres Torres, Barcelona, Not set

Hospital Quirónsalud Barcelona, Barcelona, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

Hospital Universitario de Jaén, Jaén, Not set

MD Anderson Cancer Center Madrid, Madrid, Not set

Hospital Universitario Fundación Jiménez Díaz, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Regional Universitario de Málaga - Hospital General, Málaga, Not set

Faculty of Medicine Siriraj Hospital, Bang Phlat, Bangkok

King Chulalongkorn Memorial Hospital, Pathum Wan, Bangkok

Navamindradhiraj University - Faculty of Medicine Vajira Hospital, Krung Thep Maha Nakhon, Khet Dusit

T.C. Saglik Bakanligi Adana Sehir Egitim ve Arastirma Hastanesi, Adana, Not set

Medical Park Seyhan Hastanesi, Adana, Not set

Hacettepe Üniversitesi Kanser Enstitüsü, Ankara, Not set

Memorial Ankara Hastanesi, Ankara, Not set

Trakya Üniversitesi Sa?l?k Ara?t?rma ve Uygulama Merkezi, Edirne, Not set

Ankara Il Saglik Mudurlugu SBU Gulhane Egitim Ve Arastirma Hastanesi, Etlik, Not set

Bagcilar Medipol Mega Universite Hastanesi, Istanbul, Not set

T.C. Saglik Bakanligi - Istanbul Il Saglik Mudurlugu - Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi, Istanbul, Not set

T.C. Saglik Bakanligi Ankara Bilkent Sehi?r Hastanesi?, Çankaya, Not set

Royal Free London NHS Foundation Trust, London, England

Nottingham University Hospitals NHS Trust, Nottingham, England

Torbay and South Devon NHS Foundation Trust, Torquay, England

Conditions: Advanced or Metastatic NSCLS With Exon 20 Insertion Mutation

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Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

NCT05315700

Recruiting

The purpose of this study is to establish the recommended Phase 2 dose (RP2D) and/or maximum tolerated dose (MTD), safety, pharmacokinetics (PK), pharmacodynamics (PD), and antitumor activity of ORIC-114 as a Single Agent or in Combination with Chemotherapy when administered to patients with advanced solid tumors harboring an EGFR or HER2 alteration.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/31/2025

Locations: City of Hope, Duarte, California +41 locations

City of Hope, Duarte, California

City of Hope, Huntington Beach, California

City of Hope, Irvine, California

City of Hope, Long Beach, California

University of California, San Francisco, San Francisco, California

Yale Cancer Center, New Haven, Connecticut

Georgetown University, Washington, District of Columbia

Mayo Clinic, Jacksonville, Florida

Moffitt Cancer Center, Tampa, Florida

Northwestern University, Chicago, Illinois

Dana Farber Cancer Institute, Boston, Massachusetts

Mayo Clinic, Rochester, Minnesota

NYU Langone Health Perlmutter Cancer Center, New York, New York

Duke Cancer Institute, Durham, North Carolina

University of Pennsylvania, Philadelphia, Pennsylvania

Spartanburg Regional Healthcare System, Spartanburg, South Carolina

Next Oncology, Fairfax, Virginia

Chris O'Brien Lifehouse, Camperdown, Not set

Peter MacCallum Cancer Centre, Melbourne, Not set

One Clinical Research, Hollywood Medical Centre, Nedlands, Not set

Sydney Adventist Health, Sydney, Not set

Princess Margaret Cancer Centre, Toronto, Ontario

The Chinese University of Hong Kong, Shatin, Not set

Chungbuk University Hospital, Cheongju-si, Not set

National Cancer Center, Goyang-si, Not set

Catholic University of Korea, St, Vincent Hospital, Gyeonggi-do, Not set

Gachon University Hospital, Incheon, Not set

Seoul National Bundang Hospital, Seongnam-si, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Sultan Ahmad Shah Medical Centre at International Islamic University Malaysia (IIUM), Kuantan, Pahang

Pulau Pinang Hospital, George Town, Penang

Sarawak General Hospital (SGH), Kuching, Sarawak

Hospital Kuala Lumpur, Kuala Lumpur, Not set

University of Malaya Medical Center (UMMC), Kuala Lumpur, Not set

Medical University of Gdańsk, Gdańsk, Not set

NEXT Oncology - Barcelona, Barcelona, Not set

Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Not set

NEXT Oncology - Madrid, Madrid, Not set

National Taiwan University Hospital, Taipei, Not set

The Christie NHS Foundation Trust, Manchester, England

Conditions: Solid Tumors

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Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma

NCT06341712

Recruiting

The participants of this study will be children, adolescents, and young adults with residual osteosarcoma, which cannot be removed completely through surgery. Participants will have achieved a partial response or stable disease at the end of conventional chemotherapy. Osteosarcoma is cancer of the bone. The cancer cells make immature bone cells, known as osteoid. Osteosarcoma is very rare, but it is the most common type of bone cancer in children and teens. It is most common in teens and young... Read More

Gender:

ALL

Ages:

Between 5 years and 30 years

Trial Updated:

07/31/2025

Locations: University of Southern California (USC) - Norris Cancer Hospital, Los Angeles, California +73 locations

University of Southern California (USC) - Norris Cancer Hospital, Los Angeles, California

Stanford University and Lucile Packard Children's Hospital, Palo Alto, California

University of Florida Health Shands Children's Hospital, Gainesville, Florida

Levine Children's Hospital (LCH), Charlotte, North Carolina

Cincinnati Children's Hospital Medical Center - Cancer and Blood Diseases Institute (CBDI), Cincinnati, Ohio

MD Anderson Main Campus, Houston, Texas

Children's Hospital of the King's Daughters, Norfolk, Virginia

St. Anna Kinderspital Zentrum fuer Kinder- und Jugendheilkunde, Vienna, Not set

Cliniques universitaires Saint-Luc, Bruxelles, Not set

University Hospital Gent, Ghent, Not set

Universitaire Ziekenhuizen Leuven, Leuven, Not set

Arthur J. E. Child Comprehensive Cancer Centre, Calgary, Not set

McGill University Health Centre - Centre for Innovative Medicine, Québec, Not set

Princess Margaret cancer center, Toronto, Not set

Sinai Health System-Mount Sinai Hospital, Toronto, Not set

Aarhus University Hospital, Aarhus, Not set

Copenhagen University Hospital - Rigshospitalet, Kobenhavn, Not set

Institut Bergonie, Bordeaux, Not set

Centre Francois Baclesse, Caen, Not set

Centre Oscar Lambret, Lille, Not set

Centre Leon Berard, Lyon, Not set

CHU de Nantes, Nantes, Not set

AP-HP Hopital Cochin, Paris, Not set

Institut Curie, Paris, Not set

CHU de Poitiers (Poitiers), Poitiers, Not set

CHU de Poitiers, Poitiers, Not set

CHU de Rouen - Hôpital Charles-Nicolle, Rouen, Not set

CHRU de Strasbourg - Hopital de Hautepierre, Strasbourg, Not set

CHU de Toulouse - Hôpital des Enfants, Toulouse, Not set

Gustave Roussy, Villejuif, Not set

Charité - Kinderonkologie, Berlin, Not set

Klinikum Dortmund, Dortmund, Not set

Universitaetsklinikum Carl Gustav Carus Dresden, Dresden, Not set

Universitätsklinikum Essen Westdeutsches Tumorzentrum Essen, Essen, Not set

Klinikum Kassel Gesundheit Nordhessen, Kassel, Not set

Universitaetsklinikum Köln - Kinderonkologie, Köln, Not set

Universitätsmedizin Mainz, Mainz, Not set

Klinikum rechts der Isar der Technischen Universitaet Muenchen, Muenchen, Not set

Dr. von Haunerschen Kinderspital, München, Not set

Medizinischen Klinik III - Onkologie und Hämatologie - am LMU Klinikum, München, München, Not set

Olgahospital, Stuttgart, Not set

St Vincent's University Hospital, Dublin, Not set

Ospedale Ortopedico Rizzoli di Bologna, Bologna, Not set

Azienda Ospedaliero Universitaria Meyer, Firenze, Not set

IRCCS Istituto Giannina Gaslini, Genova, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Not set

Istituto Nazionale Tumor, Naples, Not set

Azienda Ospedale - Università Padova, Padova, Not set

AOU Città della Salute e della Scienza di Torino, Piemonte, Not set

IRCCS - Istituto Nazionale Tumori Regina Elena, Roma, Not set

Ospedale Paediatrico Bambino Gesù, Roma, Not set

Azienda Ospedaliero-Universitaria Senese, Siena, Not set

AOU Citta della Salute e della Scienza di Torino - Ospedale Regina Margherita, Torino, Not set

Amsterdam UMC - Locatie AMC, Amsterdam, Not set

Princess Maxima Center for paediatric oncology, Utrecht, Not set

Instytut Matki i Dziecka, Warsaw, Not set

Hospital de La Santa Creu i Sant Pau, Barcelona, Not set

Hospital Sant Joan de Deu, Barcelona, Not set

Hospital Universitario Vall d'Hebron, Barcelona, Not set

Hospital Universitario La Paz, Castellana, Not set

Hospital General Unversitario Gregorio Marañón (Madrid), Madrid, Not set

Hospital General Unversitario Gregorio Marañón, Madrid, Not set

Hospital Infantil Universitario Nino Jesus, Madrid, Not set

Hospital Universitario Son Espases, Palma De Mallorca, Not set

Complejo Hospitalario Universitario de Santiago, Santiago De Compostela, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital Universitari i Politecnic La Fe, Valencia, Not set

Karolinska University Hospital, Stockholm, Not set

Birmingham Children's Hospital, Birmingham, Not set

Cambridge University Hospitals NHS Trust, Cambridge, Not set

NHS greater Glasgow and Clyde, Glasgow, Not set

University College London Hospital, London, Not set

Christie NHS Foundation Trust, Manchester, Not set

Royal Victoria Infirmary, Newcastle Upon Tyne, Not set

Conditions: Osteosarcoma, Osteosarcoma in Children, Osteosarcoma in Adolescents and Young Adults

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Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis

NCT06444113

Recruiting

This study will evaluate whether ofatumumab is excreted at quantifiable levels and at which concentrations in breast milk of lactating women with RMS). The study will include lactating mothers who plan to breastfeed and initiate/re-initiate ofatumumab 2-24 weeks post-partum.

Gender:

FEMALE

Ages:

Between 18 years and 100 years

Trial Updated:

07/31/2025

Locations: UCSF, San Francisco, California +16 locations

Conditions: Multiple Sclerosis

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