There are currently 593 clinical trials in Richmond, Virginia looking for participants to engage in research studies. Trials are conducted at various facilities, including Virginia Commonwealth University, Virginia Commonwealth University/Massey Cancer Center, Virginia Cancer Institute and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee
Recruiting
The purpose of this study is to evaluate performance of the Vanguard 360 revision knee system utilizing offset on either the tibial component, femoral component, or both in terms of the restoration of mechanical alignment, clinical outcomes and survivorship.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: OrthoVirginia West End Orthopedic Clinic, Richmond, Virginia
Conditions: Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Post Traumatic Deformity, Complications; Arthroplasty, Deformity of Limb
Behavioral Exercise TRaining for Men Undergoing Androgen Depr Therapy for Prostate Ca
Recruiting
To refine a remote behavioral exercise training intervention for testing in a larger randomized trial.
Gender:
MALE
Ages:
Between 41 years and 85 years
Trial Updated:
02/20/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Prostate Cancer
ASHBY: Accelerated Super-Hypofractionated Breast Brachytherapy
Recruiting
The purpose of this study is to compare any good and bad effects of giving radiation treatment for breast cancer in 3 treatments over about 2 days.
Gender:
FEMALE
Ages:
Between 45 years and 79 years
Trial Updated:
02/20/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Breast Cancer
Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation
Recruiting
The primary purpose of this registry is to obtain real-world clinical experience of Paroxysmal (PAF) and Persistent (PsAF) Atrial Fibrillation ablation radiofrequency (RF) technologies. Data from the registry will be used to assess clinical outcomes, including procedural efficiency, safety, and long-term, effectiveness of catheter ablation with novel RF technologies in PAF and PsAF patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: CJW Medical Center, Richmond, Virginia
Conditions: Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
4D-710 in Adult Patients With Cystic Fibrosis
Recruiting
This is a Phase 1/2 multicenter, open-label, single dose trial of 4D-710 investigational gene therapy in adults with cystic fibrosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: Virginia Commonwealth University Health System, Richmond, Virginia
Conditions: Cystic Fibrosis Lung
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Recruiting
The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, pH and food effect, and preliminary efficacy of BMS-986470 in healthy volunteers and participants with sickle cell disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Local Institution - 0014, Richmond, Virginia
Conditions: Anemia, Sickle Cell, Healthy Volunteers
Research Participation With Transgender and Gender-Diverse Youth
Recruiting
Research has historically excluded the participation of transgender and gender-diverse people. The purpose of this research study is to find out about what goes into a transgender and gender-diverse youth's decision to participate in research. The results of this study will be used to improve access to research for transgender and gender-diverse youth and therefore, improve the representation of transgender and gender-diverse youth as research participants in research.
Gender:
ALL
Ages:
Between 15 years and 21 years
Trial Updated:
02/17/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Transgender Persons
The Purpose of This Study is to Determine Whether CerebroFlo™ EVD Catheter is Effective During the Treatment of IVH
Recruiting
The primary goal of this study is to assess the occurrence of flushing interventions to address occlusions during the treatment of interventricular hemorrhage (spontaneous primary IVH or secondary IVH due to ruptured aneurysm).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/17/2025
Locations: Virginia Commonwealth University Department of Neurosurgery, Richmond, Virginia
Conditions: Intraventricular Hemorrhage, Subarachnoid Hemorrhage
Using Dichoptic Therapy to Treat Intermittent Exotropia
Recruiting
Intermittent exotropia is difficult to treat. The mainstay of treatment involves surgery, and in one long-term study authors found that as many as 60% of IXT required at least one re-operation.Patching of the non-dominant eye has also been tested in a large, multi-center randomized control trial and was not found to have a large benefit. More non-surgical treatment modalities are critical to improve the care in this condition.
Gender:
ALL
Ages:
Between 4 years and 7 years
Trial Updated:
02/14/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Exotropia Intermittent
Mindfulness in the OR
Recruiting
The purpose of this research study is to understand the effect of a short mindfulness video on self perceived performance in the OR. Specifically, assessing the effectiveness of brief mindfulness intervention on physician focus, anxiety and perceived performance at the time of a procedure through a survey containing a modified flow state scale and modified applied mindfulness process scale
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Performance at Work
Implantation of BioSphincter TM for Treatment of Severe Passive Fecal Incontinence
Recruiting
This is first-in-human prospective Phase I study of the immediate and long-term safety of an implanted internal anal sphincter (IAS) bioengineered from autologous cells to treat subjects with severe passive FI who have failed standard treatments.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Virginia Commonwealth University Health Main Hospital (VCU), Richmond, Virginia
Conditions: Fecal Incontinence
Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections
Recruiting
This is a Phase 3 multi-center, group-randomized, crossover trial to compare nasal antimicrobial photodisinfection therapy (aPDT) with standard of care for prevention of surgical site infections in patients undergoing major elective, urgent, or emergent surgeries in a hospital setting. The main outcomes are to: 1. compare the efficacy, and 2. estimate the safety of applying nasal (aPDT) before surgery in reducing the incidence of SSIs within the initial 30 days after surgery compared to standar... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2025
Locations: Johnston Willis Hospital, Richmond, Virginia
Conditions: Surgical Site Infections, Surgical Wound Infection, Infections, Anti-Infective Agents