There are currently 587 clinical trials in Richmond, Virginia looking for participants to engage in research studies. Trials are conducted at various facilities, including Virginia Commonwealth University, Virginia Commonwealth University/Massey Cancer Center, GSK Investigational Site and Virginia Cancer Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial
NCT04095663
Recruiting
The COSMID (Comparison of Surgery and Medicine on the Impact of Diverticulitis) trial is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. A parallel observational cohort will include those who are disinclined to have their treatment choice randomized, but are willing to contribute information about their outcomes. The goal of the COSMID trial is to answer the question:... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/06/2023
Locations: VCU Medical Center, Richmond, Virginia
Conditions: Diverticulitis
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Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study
NCT04967365
Recruiting
Pediatric Intensive Care Unit (PICU) survival has increased substantially over the past three decades. Currently, an understanding of PICU morbidity and recovery among PICU survivors and their families is limited. Post-intensive care syndrome (PICS) consists of new or worsening impairments in physical, cognitive, or mental health status that arise and may persist after critical illness. The characteristics of PICS in children (PICS-p) are unknown. The objective of this study is to learn about pe... Read More
Gender:
All
Ages:
Between 1 month and 16 years
Trial Updated:
09/06/2023
Locations: Children's Hospital of Richmond, Richmond, Virginia
Conditions: Critical Illness, Post Intensive Care Unit Syndrome
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Operative Versus Non-Operative Treatment for Atraumatic Rotator Cuff Tears
NCT03295994
Recruiting
Rotator cuff tears are one of the most common reasons to seek musculoskeletal care in the United States and one of the fastest growing ambulatory surgery procedures. However, data on comparison of operative versus non-operative treatment is lacking and urgently needed.
Gender:
All
Ages:
Between 40 years and 84 years
Trial Updated:
09/05/2023
Locations: Ortho Virginia, Richmond, Virginia
Conditions: Rotator Cuff Tear
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A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis
NCT05181137
Recruiting
This is a randomized, double-blind, placebo-controlled, multicenter Phase 3 study that will enroll approximately 368 subjects aged 18 to 75 years old with Moderately to Severely Active Ulcerative Colitis.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
09/01/2023
Locations: McGuire Research Institute, Richmond, Virginia
Conditions: Ulcerative Colitis
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Engaging Black Men in Colorectal Cancer Screening
NCT05980182
Recruiting
To determine the unmet needs, attitudes, barriers and facilitators of African American (AA)/ Black men use of colorectal cancer screening and describe how community leaders such as barbers may act as Community Champions to educate and facilitate screening participation.
Gender:
Male
Ages:
Between 45 years and 74 years
Trial Updated:
08/29/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Colorectal Cancer, CRC, Behavior
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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
NCT03851445
Recruiting
This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will determine to which sub-study, within this protocol, a participant will be assigned to compare new targeted cancer therapy, designed to block the growth and spread of cancer, or combinations to standard of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/28/2023
Locations: Bon Secours Saint Mary's Hospital, Richmond, Virginia +3 locations
Conditions: Previously Treated Non-Small Cell Lung Cancer
Register for Updates
OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study
NCT05405374
Recruiting
The objective of this clinical study is to compare OSTEOAMP SELECT Fibers to Infuse Bone Graft, in terms of effectiveness and safety, when used as a bone graft substitute in in skeletally mature patients qualified for 2-lumbar interbody fusion (LIF) by means of an intra-patient control model.
Gender:
All
Ages:
Between 21 years and 80 years
Trial Updated:
08/25/2023
Locations: OrthoVirginia, Richmond, Virginia
Conditions: Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease
Register for Updates
Prematurity Risk Assessment Combined With Clinical Interventions for Improving Neonatal outcoMEs
NCT04301518
Recruiting
This prospective, randomized, controlled study evaluates the safety and efficacy of a preterm birth (PTB) prevention strategy versus standard of care pregnancy management to reduce the incidence of adverse pregnancy outcomes.
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/24/2023
Locations: VPFW, Richmond, Virginia
Conditions: Preterm Labor, Preterm Birth
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Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients
NCT05586958
Recruiting
The aim of this 6-month randomized multi-regional double-blind parallel group placebo-controlled phase 3 study is to assess the efficacy and safety of three different doses of Tigulixostat in gout patients with hyperuricemia.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/24/2023
Locations: Dominion Medical Associates, Inc., Richmond, Virginia +1 locations
Conditions: Gout, Hyperuricemia, Gout Flare, Tophi
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Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury
NCT05005026
Recruiting
The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/17/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Spinal Cord Injuries, Neuropathic Pain
Register for Updates
Effects of Electronic Cigarette Flavors on Abuse Liability in Smokers (P3-Taste)
NCT05971823
Recruiting
The purpose of this study is to determine if abuse liability indices will be impacted by varying flavors and e-cigarette (ECIG) nicotine delivery capability (i.e., nicotine flux) among current combustible cigarette users. The investigators will compare abuse liability indices between three FDA-authorized ECIG products that vary in nicotine flux (but are all tobacco flavor) and own brand cigarettes. The investigators will also test the influence of ECIG flavor availability (tobacco vs. menthol)... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
08/17/2023
Locations: Center for the Study of Tobacco Products, Richmond, Virginia
Conditions: Electronic Cigarette Use
Register for Updates
Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD
NCT05407636
Recruiting
RGX-314 is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD). Wet AMD is characterized by loss of vision due to new, leaky blood vessel formation in the retina. Wet AMD is a significant cause of vision loss in the United States, Europe and Japan, with up to 2 million people living with wet AMD in these geographies alone. Current anti-VEGF therapies have significantly changed the landscape for treatment of wet AMD, b... Read More
Gender:
All
Ages:
Between 50 years and 89 years
Trial Updated:
08/17/2023
Locations: Retina Institute of Virginia, Richmond, Virginia
Conditions: AMD, nAMD, Wet Age-related Macular Degeneration, wAMD, WetAMD, CNV
Register for Updates