There are currently 220 clinical trials in Spokane, Washington looking for participants to engage in research studies. Trials are conducted at various facilities, including Cancer Care Northwest - Spokane South, Providence Sacred Heart Medical Center and Children's Hospital, Evergreen Hematology and Oncology, PS and Premier Clinical Research. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters
NCT05365451
Recruiting
The objective of this study is to confirm the feasibility of using a panel of endogenous substrates/metabolites as a robust biomarker of OCTs and OATs by conducting a controlled, comprehensive clinical drug-drug interaction study in healthy adult volunteers. Metformin and furosemide will be used as probe drugs for OCTs and OATs, respectively; cimetidine and probenecid will be used as corresponding inhibitors. Results from this study will validate this novel approach, which will be extended to ch... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/17/2024
Locations: Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane, Washington
Conditions: Interaction, Endogenous Biomarkers
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Evaluating a Potential Pharmacokinetic Kratom-oxycodone Interaction Concurrent With Clinical Endpoints
NCT05846451
Recruiting
The goal of this study is to investigate whether the botanical product kratom affects how the body processes the opioid drug oxycodone. The main research questions to be answered are two-fold: 1. How does kratom affect the manner in which oxycodone is metabolized (broken down and removed) by the body? 2. Does kratom change the effects oxycodone exerts on the body? Healthy adult participants will complete four study arms, during which they will be given the following: * Kratom (as a tea) * A s... Read More
Gender:
ALL
Ages:
Between 21 years and 45 years
Trial Updated:
12/17/2024
Locations: Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane, Washington
Conditions: Herbal Interaction
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Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects
NCT05172726
Recruiting
This is an open-label, multi-center, Phase 3 study to evaluate tapinarof cream, 1% in pediatric subjects with plaque psoriasis.
Gender:
ALL
Ages:
Between 2 years and 17 years
Trial Updated:
12/05/2024
Locations: Dermavant Clinical Site, Spokane, Washington +1 locations
Conditions: Plaque Psoriasis
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Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
NCT05658575
Recruiting
The purpose of this trial is to investigate the efficacy and safety of dapansutrile (OLT1177®) tablets in subjects with an acute gout flare.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2024
Locations: Arthritis Northwest, Spokane, Washington
Conditions: Acute Gout Flare, Gout Attack, Gout Flare, Gouty Arthritis, Gout, Arthritis, Joint Pain
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Hyperbaric Oxygen Treatment (HBOT) During Methadone Tapering
NCT05924022
Recruiting
The aims of this study are to 1) explore the efficacy of hyperbaric oxygen therapy (HBOT) applied at two different pressures compared to sham treatment in relieving signs and symptoms (both physical and psychological) of opioid withdrawal in human subjects associated with methadone dose reductions; and 2): explore whether HBOT can increase the odds of successful methadone dose reduction in patients who are interested in tapering their opioid dose. The investigators aim to explore, through qualit... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/23/2024
Locations: Spokane Regional Health District, Spokane, Washington
Conditions: Opioid Use Disorder
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Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail Approach
NCT06693960
Recruiting
The purpose of this clinical trial is to determine how the supplement oregano affects how the body metabolizes pharmaceutical drugs.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
11/22/2024
Locations: Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane, Washington
Conditions: Interaction
Register for Updates
Effects of a Hemp Product on the Pharmacokinetics and Pharmacodynamics of Clopidogrel
NCT06692933
Recruiting
The goal of this clinical trial is to determine how two different doses of cannabidiol (CBD), given as a hemp product, change the blood concentrations of the drug clopidogrel in the body. Results will be used to help design future studies and to assist healthcare providers in informing their patients about the safe use of CBD.
Gender:
ALL
Ages:
Between 21 years and 64 years
Trial Updated:
11/15/2024
Locations: Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane, Washington
Conditions: Interaction
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Contribution of UGT2B17 to the Pharmacokinetics of Diclofenac
NCT06053411
Recruiting
The purpose of this pilot study is to gather preliminary data on the (1) contribution of the understudied drug metabolizing enzyme, UDP-glucuronosyltransferase (UGT) 2B17, to the metabolism of a widely used medication, diclofenac, and (2) impact of the UGT2B17 inhibitor and natural product, curcumin, on diclofenac pharmacokinetics. Results will inform future studies aimed to assess the effects of UGT2B17 genetic polymorphisms and co-consumed xenobiotics on the pharmacokinetics and toxicity risk... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/14/2024
Locations: Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane, Washington
Conditions: Interaction
Register for Updates
A Prospective Total Joint Surgery Registry to Monitor Short- and Long-Term Clinical Outcomes
NCT06687109
Recruiting
The investigators propose a prospective longitudinal registry study to collect and compare preoperative and postoperative information from patients who undergo total joint arthroplasty (TJA). Outcomes will be assessed with common, routinely available patient-reported outcomes measures (PROM's) such as the HOOS Jr., Oxford score, Knee Society Score, Harris Hip Score, and other patient satisfaction and function assessments in use in Orthopedics.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/11/2024
Locations: Spokane Joint Replacement Center, Spokane, Washington
Conditions: Osteoarthritis
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Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study
NCT04331769
Recruiting
Prospective, randomized, open-label, international, multi-center clinical study to evaluate the safety and efficacy of the AccuCinch Ventricular Restoration System in patients with heart failure and reduced ejection fraction (HFrEF).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/08/2024
Locations: Providence Sacred Heart Medical Center, Spokane, Washington
Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
Register for Updates
Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer
NCT05254171
Recruiting
The study is a randomized, double-blind, placebo-controlled, multicenter study of standard treatment with nab-paclitaxel and gemcitabine with or without SBP-101 in subjects previously untreated for metastatic pancreatic ductal adenocarcinoma (PDA), including subjects who have received prior neoadjuvant or adjuvant treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: Medical Oncology Associates - Spokane, Spokane, Washington
Conditions: Pancreatic Cancer Metastatic, Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer Stage IV
Register for Updates
Interventional Study Exploring the Occurrence of Surgical Site Infections.
NCT06661473
Recruiting
Interventional study exploring surgical site complication occurrences in high-risk revision patients undergoing TKA or THA using NPWT.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/25/2024
Locations: Spokane Joint Replacement Center, Spokane, Washington
Conditions: Total Knee Arthroplasty, Total Hip Arthroplasty Revision, Total Knee Arthroplasty Revision
Register for Updates