Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs
NCT06674980
Recruiting
The purpose of the study is to evaluate the efficacy of multiple human placental membrane products and Standard of Care (SOC) versus SOC alone in the management of nonhealing diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs) over 12 weeks using a modified platform trial design.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2024
Locations: Poirot Podiatry, Metairie, Louisiana
Conditions: Pathologic Processes, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Diseases, Endocrine System Disease, Diabetic Angiopathies, Vascular Diseases, Cardiovascular Diseases, Leg Ulcer, Skin Ulcer, Skin Diseases, Diabetes Complications, Diabetic Neuropathies, Foot Diseases, Diabetic Foot, Foot Ulcer, Diabetes Mellitus, Type 2, Ulcer, Foot Ulcer Unhealed
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Mindfulness-Based Intervention for Latino Cancer Patients and Their Caregivers
NCT04870788
Recruiting
This clinical trial develops effective and appropriate mindfulness-based interventions that help meet the needs of Latino cancer patients and their family caregivers. Mindfulness-based interventions focus on building awareness of thoughts, emotions/feelings, and the sensations. This study may help improve mental well-being and reduce stress and anxiety associated with having cancer or with a family member's cancer diagnosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2024
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Advanced Malignant Solid Neoplasm
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5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer
NCT05381597
Recruiting
The investigators will compare the application of two different creams for the treatment of low-risk skin cancers-superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis). 5-Fluorouracil cream is currently FDA approved for the treatment of superficial basal cell carcinoma and is routinely used by dermatologists across the country and at Boston Medical Center (BMC) for SCCis. The normal treatment regimen is 4 weeks of the 5-fluorouracil cream for both skin cancers. The... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2024
Locations: Boston Medical Center Dermatology Clinic, Boston, Massachusetts
Conditions: Superficial Basal Cell Carcinoma, Squamous Cell Carcinoma in Situ
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Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age
NCT05871970
Recruiting
This is a Phase 2a/b single arm open label study to evaluate the safety, reactogenicity, and efficacy of intracystic injection of TARA-002 in participants 6 months to less than 18 years of age for the treatment of macrocystic and mixed cystic lymphatic malformations. The Phase 2a safety lead-in, age de-escalation study is designed to establish the safety of TARA-002 in older participants 6 years to less than 18 years before proceeding to younger participants 2 years to less than 6 years, then 6... Read More
Gender:
ALL
Ages:
Between 6 months and 18 years
Trial Updated:
12/20/2024
Locations: Children's Hospital of Alabama, Birmingham, Alabama +9 locations
Conditions: Lymphatic Malformation
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Long-Term Safety and Clinical Outcomes of Livmarli in Patients With Alagille Syndrome (LEAP)
NCT06193928
Recruiting
The goal of this observational study is to evaluate the long-term safety and clinical outcomes of Livmarli prescribed to patients with Alagille Syndrome (ALGS).
Gender:
ALL
Ages:
All
Trial Updated:
12/20/2024
Locations: Children's Hospital Los Angeles CHLA, Los Angeles, California +7 locations
Conditions: Alagille Syndrome
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A Trial for a Preliminary Estimate of the Effectiveness of a Novel Theoretical Framework
NCT06461416
Recruiting
* Aim 1: To determine the preliminary effect sizes of al ActiveHeal EST (Engage-Sustain-Triumph) Program on occupational resilience. * Aim 2: To determine the preliminary effect sizes of ActiveHeal EST (Engage-Sustain-Triumph) on health status \[quality of life (QoL) and Psychological wellbeing (PWB)\]. * Aim 3: To determine the extent to which ActiveHeal EST (Engage-Sustain-Triumph) Program is an acceptable and feasible Intervention for breast and prostate cancer survivors.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
12/20/2024
Locations: University of Arkansas for Medical Science, Fayetteville, Arkansas
Conditions: Prostate Cancer, Breast Cancer
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Transforming Robot-mediated Telerehabilitation: Citizen Science for Rehabilitation
NCT03096262
Recruiting
The purpose of this study is to advance upper limb robot-mediated tele-rehabilitation for patients recovering from stroke by empowering them through active science participation. By varying the tasks' features and affordances of a platform that combines a low-cost haptic device on one hand, and an online citizen science platform on the other, investigators will evaluate different strategies for social telerehabilitation. the two fundamental modes of social interaction - competition and cooperati... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/20/2024
Locations: Matthew Bird, Baltimore, Maryland
Conditions: Hemiparesis, Stroke
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Telehealth for Pain and Unhealthy Drinking Among PLWH
NCT05503173
Recruiting
This randomized controlled trial is a between-groups design to compare the Motivational and Cognitive Behavioral Management for Alcohol and Pain (MCBMAP) Intervention to a Brief Advice and Information Control condition. Two-hundred and fifty participants who have HIV with moderate or greater chronic pain will be randomized for the trial. Recruitment will take place through digital media. A unique feature of this intervention trial is that most of the procedures will be conducted remotely which... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2024
Locations: Charles River Campus, Boston University, Psychology Department- remote study, Boston, Massachusetts
Conditions: HIV, Chronic Pain, Unhealthy Alcohol Use
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Family Teams: A Study to Promote Team Collaboration in Family Medicine Clinics
NCT06011239
Recruiting
This project includes an intervention in five Michigan Medicine family medicine clinics which is designed to improve staff collaboration across different job roles.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2024
Locations: University of Michigan-Domino Farms, Ann Arbor, Michigan +4 locations
Conditions: Patient Care Team, Psychological Well-Being, Occupational Burnout
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Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Participants With Autoimmune Disease
NCT06293365
Recruiting
The purpose of this study is to demonstrate the comparability of ianalumab exposure following the sub-cutaneous (s.c.) administration of one injection of 300 mg/2 mL auto-injector (AI) versus two injections of 150 mg/1 mL pre-filled syringe (PFS), and to evaluate the safety and tolerability of ianalumab following the s.c. administration of both devices in participants with rheumatoid arthritis (RA), Sjögren's disease (SjD), or systemic lupus erythematosus (SLE). A second optional cohort may be... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
12/20/2024
Locations: Pinnacle Research Group Llc, Anniston, Alabama +29 locations
Conditions: Sjögrens Disease, Systemic Lupus Erythematosus, Rheumatoid Arthritis
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Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body
NCT06470243
Recruiting
This phase III trial compares the effect of adding carboplatin to the standard of care chemotherapy drug cabazitaxel versus cabazitaxel alone in treating prostate cancer that keeps growing even when the amount of testosterone in the body is reduced to very low levels (castrate-resistant) and that has spread from where it first started (primary site) to other places in the body (metastatic). Carboplatin is in a class of medications known as platinum-containing compounds. Carboplatin works by kill... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
12/20/2024
Locations: Highlands Oncology Group - Fayetteville, Fayetteville, Arkansas +173 locations
Conditions: Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8
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Shoulder Innovations Clinical Data Registry
NCT06754150
Recruiting
The goal of this multi-center observational study is to collect long-term clinical outcome information for anatomic and reverse total shoulder arthroplasty (shoulder replacement).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2024
Locations: Western Orthopaedics, Denver, Colorado +1 locations
Conditions: Shoulder Arthroplasty
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