Stereotactic Body Proton Therapy for Treatment of Primary Renal Cell Carcinoma
NCT06376669
Recruiting
This study examines the impact of proton based stereotactic radiation therapy (SBRT) on kidney function as well as other oncologic outcomes including local control, locoregional and systemic failure, progression free and overall survival.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Sibley Memorial Hospital, Washington, District of Columbia
Conditions: Renal Cell Carcinoma
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An INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY to ASSESS the PERFORMANCE of the CORDIO HEARO SYSTEM
NCT06378632
Recruiting
Study Design: This is an international, multicenter, observational, non-interventional, prospective, blinded, single-arm, two-period study, to collect patient utterances that will be retrospectively analyzed to determine the sensitivity and UPNR of the HearO system.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/25/2025
Locations: Eastern Shore Research Institute, Fairhope, Alabama +44 locations
Conditions: Heart Failure
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InvesT1D: Promoting Adolescent Investment in Diabetes Care
NCT06384911
Recruiting
The goal of this clinical trial is to see if a financial incentives program called InvesT1D is helpful to support diabetes management in adolescents with type 1 diabetes. Adolescent participants will be randomized to usual care or receive financial incentives for meeting diabetes self-management and clinical outcomes goals during the study. Researchers will compare changes in glucose levels, as well as adolescent and caregiver person-reported outcomes between groups.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
03/25/2025
Locations: Seattle Children's, Seattle, Washington
Conditions: Type 1 Diabetes
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Raman Spectroscopy and Skin Cancer
NCT06384924
Recruiting
The goal of this observational study is to find out if Raman Spectroscopy, a type of imaging, can be used to determine the size of skin cancer tumors. The main question it aims to answer is: -Can Raman Spectroscopy help figure out how far a tumor spreads? This study will take measurements using laser light from an experimental, handheld probe by lightly touching the skin.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Stony Brook Hospital, Stony Brook, New York
Conditions: Skin Cancer, Basal Cell Carcinoma, Squamous Cell Carcinoma
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Nightmare Deconstruction and Reprocessing vs. NightWare Wristband
NCT06399874
Recruiting
The overall goal of this Phase IIa randomized controlled pilot trial is to assess the potential efficacy of two emerging treatments for post-trauma nightmares and to test the feasibility of study design and methods. Symptom change will be assessed in two treatment arms: (1) Nightmare Deconstruction and Reprocessing (NDR), an exposure-based psychotherapy; and (2) NightWare (NW), a non-exposure approach using a wristband device. The investigators will also assess the feasibility of circadian-depen... Read More
Gender:
ALL
Ages:
Between 22 years and 64 years
Trial Updated:
03/25/2025
Locations: Uniformed Services University of the Health Sciences, Bethesda, Maryland
Conditions: Nightmare
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Antidepressant Adherence for Depressed Adults in Primary Care
NCT06496646
Recruiting
The goal of this randomized controlled trial study is to compare different adherence support strategies for primary care patients with depression who have been newly prescribed antidepressant medications. We will examine whether personalized daily text messages with and without financial incentives improves anti-depressant adherence and depression symptoms as compared to treatment as usual (no messages or incentives for taking medications). We will measure adherence with a wireless pill bottle... Read More
Gender:
ALL
Ages:
Between 21 years and 64 years
Trial Updated:
03/25/2025
Locations: University of Pennsylvania Health System, Philadelphia, Pennsylvania
Conditions: Depression
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Iterative Redesign of a Multifaceted Implementation Strategy for a School-based Behavioral Skills Intervention (RUBI)
NCT06508515
Recruiting
The increased prevalence of autism spectrum disorder (1 in 36 youth) in the United States along with the exorbitant cost of care of supporting one autistic individual with and without intellectual disability across their lifespan ($2.4 and $1.4 million, respectively) creates a sense of urgency to improve outcomes for autistic youth. Schools are the primary setting in which autistic children receive intervention. Despite a growing array of evidence-based interventions (EBI) such as behavioral man... Read More
Gender:
ALL
Ages:
5 years and above
Trial Updated:
03/25/2025
Locations: University of Washington, Seattle, Washington
Conditions: Autism Spectrum Disorder
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Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans with Prediabetes
NCT06518798
Recruiting
This is a pilot study to determine the feasibility of studying the Fasting-Mimicking Diet (FMD), a dietary approach that involves the consumption of a specifically formulated, calorie-restricted nutrition regimen with a customized macronutrient composition, ratio, and quantity over a 5- day period, on a larger scale in Asian Americans with prediabetes and to examine the preliminary effects of the diet in study participants. The main questions the study aims to answer are: 1. What are the recru... Read More
Gender:
ALL
Ages:
Between 30 years and 65 years
Trial Updated:
03/25/2025
Locations: UC Irvine, Irvine, California
Conditions: Prediabetes, Prediabetic State
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Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
NCT06526858
Recruiting
HQ-HTN-G01 is a prospective, multicenter, single arm, open label, early feasibility study to evaluate initial safety and device design concept of "HyperQureTM RDN System", laparoscopic renal denervation therapy, in patients with resistant hypertension on three(3) or more antihypertensive medications
Gender:
ALL
Ages:
Between 22 years and 80 years
Trial Updated:
03/25/2025
Locations: University of Arizona Department of Urology, Tucson, Arizona +4 locations
Conditions: Resistant Hypertension
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Mindful Motivation for Reducing Binge Eating
NCT06528067
Recruiting
The aim of this study is to test how acceptable and feasible a new eating intervention is in people with overweight and binge eating. This intervention combines mindful eating with motivational interviewing to target binge eating. The main questions this clinical trial aims to answer are: How well do participants accept the new intervention (acceptability)? Is the intervention practical and easy to implement (feasibility)? In this trial researchers will compare the new eating intervention (mot... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Binge Eating, Psychological, Health Behavior, Weight, Body
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Ketogenic Diet and Brain Response in Anorexia Nervosa
NCT06540703
Recruiting
This is a longitudinal study with an open design in weight recovered anorexia nervosa (wrAN) individuals. Healthy controls (HC) will also be assessed. Study participants will be carefully assessed and will have 18F-fluorodeoxyglucose (\[18F\]FDG) positron emission tomography (PET) scans for assessment of regional brain glucose uptake. The wrAN group will be compared to healthy controls. Participants in the wrAN group will then complete 14 weeks of therapeutic ketogenic diet (TKD). At the end of... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
03/25/2025
Locations: University of California San Diego, San Diego, California
Conditions: Anorexia Nervosa
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Gemcitabine, Nab-paclitaxel Plus the TheraBionic P1 (an Amplitude-Modulated Radiofrequency Electromagnetic Fields) Device to Treat Metastatic Pancreatic Cancer
NCT06576115
Recruiting
The goal of this study is to learn if the combination of nab-paclitaxel, gemcitabine and an Amplitude-Modulated Radiofrequency Electromagnetic Fields device (Therabionic P1) is safe and effective for patients with adenocarcinoma of the pancreas.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Karmanos Cancer Institute, Detroit, Michigan
Conditions: Metastatic Pancreatic Adenocarcinoma
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