Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke
NCT03401762
Recruiting
The purpose of the study is to explore the feasibility of using a wearable device, called a myoelectric-computer interface (MCI), to improve arm movement in people who have had a stroke. Impaired arm movement after stroke is caused not just by weakness, but also by impaired coordination between joints due to abnormal co-activation of muscles. These abnormal co-activation patterns are thought to be due to abnormal movement planning.The MCI aims to reduce abnormal co-activation by providing feedb... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/21/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Stroke, Stroke, Acute
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Study of SX-682 Alone and in Combination with Oral or Intravenous Decitabine in Subjects with Myelodysplastic Syndrome
NCT04245397
Recruiting
This study will determine the safety profile, maximum tolerated dose (MTD), dose-limiting toxicities (DLT), and recommended Phase 2 dose (RP2D) of SX-682 in the treatment of patients with Myelodysplastic Syndromes (MDS).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Mayo Clinic, Jacksonville, Florida +6 locations
Conditions: Myelodysplastic Syndromes
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Vyvanse in Children Aged 6 to 12 Years
NCT05416125
Recruiting
This study will randomize children who have difficulty maintaining a healthy weight to one of two treatment groups: lifestyle therapy plus lisdexamfetamine or lifestyle therapy plus placebo.
Gender:
ALL
Ages:
Between 6 years and 12 years
Trial Updated:
11/21/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Obesity, Childhood
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Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors
NCT05687604
Recruiting
The goal of this clinical trial is to improve cancer patient's health, survival, and quality of life by dispelling risk behaviors for Northwestern Memorial Health Care (NMHC) patients who are cancer survivors. The main question\[s\] STELLAR aims to answer are: * How best to combine three behavior interventions (physical activity promotion, smoking cessation, obesity treatment) into one treatment. * Evaluate the reach of the program. We will look at the number, proportion, and representativenes... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Northwestern University-Feinberg School of Medicine, Chicago, Illinois
Conditions: Obesity, Smoking Cessation, Physical Inactivity
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A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis
NCT05995964
Recruiting
The purpose of this study is to learn about the safety and effects of 2 study medicines (PF-07275315 and PF-07264660) for the treatment of atopic dermatitis (AD). AD is a long- lasting itchy red rash, caused by a skin reaction. This study is seeking participants who: * are 18 years of age or more. * Were confirmed to have AD at least 6 months ago. * Are not having an effective treatment result from medicines that are applied on skin for AD. * Are considered by their doctors to have moderate to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Allervie Clinical Research, Birmingham, Alabama +72 locations
Conditions: Atopic Dermatitis
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Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung Cancer
NCT06427954
Recruiting
Multi-site randomized trial of the THRIVE digital health application versus usual care to evaluate the effect of THRIVE on quality of life (QOL), physical and psychological symptoms, coping, and self-efficacy in 250 patients with newly diagnosed advanced lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: University of California Los Angeles, Los Angeles, California +2 locations
Conditions: Lung Cancer
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AI-SCREENDCM Decentralized Clinical Trial - Pilot Study
NCT06609174
Recruiting
The purpose of this study is to assess the feasibility and impact of screening FDR of DCM probands using a mobile ECG with the ability to transmit the ECG for cloud-based AI analysis to detect reduced left ventricular ejection fraction (LVEF). This protocol will examine the impact of incorporating the screening AI enhanced ECG into standard of care recommendations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Cardiomyopathy
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Guerbet Liver Fibrosis
NCT06703450
Recruiting
The goal of this study is to assess the value of liver dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and texture analysis post gadopiclenol for liver fibrosis staging, in comparison with MR elastography, T1 mapping, ultrasound elastography and blood tests in 50 initial patients with metabolic dysfunction-associated steatohepatitis (MASH).
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
11/21/2024
Locations: Mount Sinai, New York, New York
Conditions: Metabolic Dysfunction-associated Steatotic Liver Disease
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Comparing Effectiveness of Duloxetine and Desipramine in Patients With Chronic Pain: A Pragmatic Trial Using Point of Care Randomization
NCT03548454
Recruiting
Over 100 million Americans suffer from chronic pain resulting in annual cost of roughly $635 billion. Limited treatments are available for this widespread disease. The data supporting these treatments lack generalizability to patients with more serious medical and psychological comorbidities who are often excluded from explanatory efficacy trials. Our work aims to integrate randomized comparative effectiveness research with patient care. The investigators will randomize the patients and collect... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Stanford Pain Management Center, Redwood City, California
Conditions: Chronic Pain
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Sensors Prediction Study
NCT04541992
Recruiting
The purpose of this study is to test whether measures of balance and agility can help predict if a Service Member may be at risk for an injury to their legs before beginning their school and training.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/21/2024
Locations: Womack Army Medical Center, Fort Bragg, North Carolina
Conditions: Injury Leg
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The Supporting Understanding of PCOS Education and Research (SUPER) Study
NCT05452642
Recruiting
This research will test whether a Dietary Approaches to Stop Hypertension (DASH) or a very low-carbohydrate diet better improves outcomes like blood glucose control and body weight for adults with polycystic ovary syndrome. Participants will have screening (includes blood draw) and baseline testing with a continuous glucose monitor and a body composition scan (called a dual-energy x-ray absorptiometry or DEXA). Once these enrollment steps are completed and the participants will be randomized to... Read More
Gender:
FEMALE
Ages:
Between 21 years and 45 years
Trial Updated:
11/21/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Polycystic Ovary
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Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure
NCT05690464
Recruiting
The purpose of this study is to assess whether 480 mg/day magnesium glycinate supplementation for 12 weeks lowers blood pressure.
Gender:
ALL
Ages:
Between 30 years and 74 years
Trial Updated:
11/21/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Blood Pressure
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