All Clinical Trials

A listing of 23115 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Featured Trial

Healthy Participants Needed (Colonoscopy + Cancer Screening)

Recruiting

Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.

Conditions:

Healthy

Healthy Volunteers

Healthy Subjects

Healthy Volunteer

Healthy Participants

Learn More

Featured Trial

Buy Retatrutide Online Through Celia

Recruiting

Retatrutide (formerly M25) is an investigational peptide being studied for its potential in supporting weight management and metabolic health. It acts on GLP-1, GIP, and glucagon receptors to influence appetite, energy regulation, and fat metabolism.

Conditions:

Healthy

Learn More

Featured Offer

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Semaglutide and Tirzepatide are advanced GLP-1 medications designed to support weight management and metabolic health. They work by targeting GLP-1 receptors in the body, helping regulate appetite, improve blood sugar control, and support sustainable weight loss (up to 22% of body weight).

Get $50 off your first order using promo code: policy-lab-50

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

Learn More

Featured Trial

Birth Control Clinical Research Study

Recruiting

Living with obesity and looking for a birth control option that is right for you? Clinical trials are now enrolling women with a body mass index (BMI) of 30 or more in the area to help study a potential new progestin-only contraceptive patch. Participating in research studies can help advance birth control options. Don’t let financial stress hold you back. All study-related assessments, care, and study patch are available at no cost. You may also be reimbursed for study-related travel.

Conditions:

Obesity

Overweight

Overweight and Obesity

Learn More

Featured Trial

Depression Clinical Trial

Recruiting

Join us in researching a potential investigational treatment for Depression. Reimbursement for study-related expenses may be available to you.

Qualifying participants:
•Are between 18-65
•Have been experiencing a major depressive episode for at least a month

Conditions:

Depression

Major Depressive Disorder

Depressive Disorder

Depressive Symptoms

Depressive Disorder

Learn More

Featured Offer

Ketamine Therapy—At Home, Clinician-Guided (Innerwell)

If you’re exploring options besides a clinical trial, Innerwell provides at-home ketamine therapy with medical oversight and structured support. Ketamine-assisted treatment may help “reset” rigid stress and mood patterns, and some people feel relief within a few sessions. Your care team works with you to tailor treatment and track progress every step of the way. Proven effective for Anxiety, PTSD, Depression, Addiction, and other disease areas.

Conditions:

Anxiety

Anxiety Disorders

Generalized Anxiety Disorder

Depression

Learn More

PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

NCT06855329

Recruiting

This is a prospective, observational cohort study. Participants with non-idiopatic pulmonary fibrosis, interstitial lung disease (ILD) will be followed for 24 months to systematically collect clinical, imaging, and biospecimen data. The primary objective is to optimize progressive pulmonary fibrosis (PPF) classification and establish PPF incidence for key ILD subtypes. Additional exploratory objectives are to 1) Prospectively validate a novel PPF classifier and assess performance durability over... Read More

Gender:

ALL

Ages:

Between 18 years and 80 years

Trial Updated:

08/18/2025

Locations: University of Massachusetts Chan Medical School, Worcester, Massachusetts +12 locations

Conditions: Progressive Pulmonary Fibrosis, Interstitial Lung Disease

Learn More ›

Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury

NCT06867809

Recruiting

Stimulation of the spinal cord and brain represents a new experimental therapy that may have potential to restore movement after spinal cord injury. While some scientists have begun to study the effect of electrical stimulation on patient's ability to walk and move their legs after lower spinal cord injury, the use of stimulation of the upper (cervical) spine to restore arm and hand function after cervical spinal cord injury remains less well explored. The investigators are doing this research s... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: NewYork-Presbyterian Hospital / Columbia University Irving Medical Center (NYPH/CUIMC), New York, New York +1 locations

Conditions: Spinal Cord Injury, Spinal Cord Injury Cervical

Learn More ›

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

NCT06548542

Recruiting

Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most frequently affecting the bowels. It can cause many different symptoms including belly pain, diarrhea, tiredness, and weight loss. Treatments are available but do not work the same for all patients or may stop working over time. This study will evaluate the effectiveness and adverse events of targeted therapies (TaTs) for adult participants with moderate to severe CD.... Read More

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/18/2025

Locations: Digestive Health Specialists /ID# 266216, Dothan, Alabama +222 locations

Digestive Health Specialists /ID# 266216, Dothan, Alabama

East View Medical Research /ID# 270377, Mobile, Alabama

Southern California Res. Ctr /ID# 265549, Coronado, California

UC San Diego Health System /ID# 265565, La Jolla, California

uc davis medical center - patient support services building /ID# 265554, Sacramento, California

Clinical Applications Laboratories - San Diego - 3rd Avenue /ID# 267391, San Diego, California

Peak Gastroenterology Associates - Colorado Springs - North Cascade Avenue /ID# 265557, Colorado Springs, Colorado

Danbury Hospital, Western Connecticut Health Network /ID# 265556, Danbury, Connecticut

Yale University School of Medicine /ID# 266786, New Haven, Connecticut

Nature Coast Clinical Research - Inverness /ID# 265874, Inverness, Florida

Atlantic Medical Research /ID# 266207, Margate, Florida

A Plus Research /ID# 265878, Miami, Florida

Sanchez Clinical Research /ID# 265887, Miami, Florida

Advanced Research Institute, Inc /ID# 265548, New Port Richey, Florida

Hillcrest Medical Research, LLC /ID# 267237, Orange City, Florida

Endoscopic Research, Inc. /ID# 267211, Orlando, Florida

AdventHealth Medical Group - Tampa - Bruce B Downs Boulevard /ID# 265538, Tampa, Florida

Florida Medical Clinic - Zephyrhills /ID# 267392, Zephyrhills, Florida

Gastroenterology Associates of Central Georgia /ID# 265547, Macon, Georgia

Treasure Valley Medical Research /ID# 267114, Boise, Idaho

University of Chicago Medical Center /ID# 267400, Chicago, Illinois

OSF St. Francis Medical Center /ID# 266973, Peoria, Illinois

Springfield Clinic Main Campus /ID# 267434, Springfield, Illinois

University of Kentucky Chandler Medical Center /ID# 265564, Lexington, Kentucky

Metropolitan Gastroenterology Group - Chevy Chase /ID# 265877, Chevy Chase, Maryland

Lucida Clinical Trials /ID# 266548, New Bedford, Massachusetts

Henry Ford Medical Center - Columbus /ID# 266503, Novi, Michigan

Mayo Clinic-Rochester /ID# 265550, Rochester, Minnesota

GI Associates Research, LLC /ID# 267433, Columbia, Missouri

BVL Clinical Research /ID# 265870, Liberty, Missouri

Washington University School of Medicine - St. Louis /ID# 266938, Saint Louis, Missouri

Vector Clinical Trials /ID# 265561, Las Vegas, Nevada

NYU Langone Long Island Clinical Research Association /ID# 265566, Great Neck, New York

Icahn School of Medicine at Mount Sinai /ID# 266857, New York, New York

Northwell Health-Lenox Hill Hospital /ID# 265527, New York, New York

Care Access - Yonkers /ID# 266781, Yonkers, New York

Digestive Health Partners - Biltmore Office /ID# 265539, Asheville, North Carolina

Velocity Clinical Research - Durham /ID# 267712, Durham, North Carolina

University of Cincinnati /ID# 265589, Cincinnati, Ohio

The Ohio State University /ID# 265577, Columbus, Ohio

Digestive Disease Specialists - Oklahoma /ID# 265901, Oklahoma City, Oklahoma

Penn State Health Milton South Hershey Medical Center /ID# 267126, Hershey, Pennsylvania

University of Pennsylvania /ID# 265904, Philadelphia, Pennsylvania

Gastroenterology Associates of Orangeburg /ID# 267548, Orangeburg, South Carolina

GI associates of Northeast Tennessee /ID# 265567, Johnson City, Tennessee

Gi Alliance - Cedar Park /ID# 268153, Cedar Park, Texas

Proactive Clinical Research /ID# 267305, El Paso, Texas

Digestive Health Associates of Texas (DHAT) Research Institute - Garland /ID# 266935, Garland, Texas

Houston Methodist Hospital /ID# 265533, Houston, Texas

Caprock Gastro Research - Lubbock - 80th Street /ID# 265541, Lubbock, Texas

GI Alliance: Mansfield /ID# 266947, Mansfield, Texas

Clinical Associates in Research Therapeutics of America, LLC /ID# 265899, San Antonio, Texas

Sun Research Institute /ID# 266723, San Antonio, Texas

Texas Digestive Disease Consultants - Southlake /ID# 265576, Southlake, Texas

Tyler Research Institute, LLC /ID# 265545, Tyler, Texas

Care Access - Ogden /ID# 266428, Ogden, Utah

Care Access - Salt Lake City /ID# 266785, Salt Lake City, Utah

Washington Gastroenterology - Tacoma /ID# 267302, Tacoma, Washington

Ordensklinikum Linz GmbH Barmherzige Schwestern /ID# 265929, Linz, Oberoesterreich

Klinikum Wels-Grieskirchen GmbH /ID# 266035, Wels, Oberoesterreich

Medizinische Universitaet Graz /ID# 275453, Graz, Steiermark

Medizinische Universitaet Innsbruck /ID# 265930, Innsbruck, Tirol

Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 265928, Salzburg, Not set

Medizinische Universitaet Wien /ID# 265926, Wien, Not set

Imelda Ziekenhuis /ID# 265995, Bonheiden, Antwerpen

Universite Libre de Bruxelles - Hopital Erasme /ID# 265993, Anderlecht, Bruxelles-Capitale

CHU Saint-Pierre /ID# 266431, Brussels, Bruxelles-Capitale

Cliniques Universitaires UCL Saint-Luc /ID# 265521, Bruxelles, Bruxelles-Capitale

Groupe Sante CHC - Clinique du MontLegia /ID# 265522, Liège, Liege

Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant /ID# 265517, Yvoir, Namur

UZ Leuven /ID# 265519, Leuven, Vlaams-Brabant

AZ Groeninge /ID# 265544, Kortrijk, West-Vlaanderen

CHU de Liege /ID# 265542, Liege, Not set

Hospital Tsaritsa Yoanna /ID# 266235, Sofiya, Sofia

Medical Center - Doverie /ID# 267050, Sofiya, Sofia

ACIBADEM City Clinic Diagnostic-Consultative Center /ID# 266239, Sofiya, Sofia

Umbal Kaspela /ID# 266234, Plovdiv, Not set

2nd Mhat /ID# 266238, Sofia, Not set

Acibadem City Clinic Tokuda University Hospital EAD /ID# 267437, Sofia, Not set

Military Medical Academy Multiprofile Hospital /ID# 267051, Sofia, Not set

UMHAT Multiprofile Hospital for Active Treatment Sveta Marina /ID# 266237, Varna, Not set

University of Calgary /ID# 265524, Calgary, Alberta

Gastroenterology and Internal Medicine Research Institute /ID# 265610, Edmonton, Alberta

University of Alberta Hospital /ID# 265614, Edmonton, Alberta

London Health Sciences Centre - University Hospital /ID# 267298, London, Ontario

Toronto Digestive Disease Associates /ID# 267358, Vaughan, Ontario

Diex Recherche Quebec Inc. /ID# 265611, Quebec, Not set

Poliklinika Solmed /ID# 265509, Zagreb, Grad Zagreb

Poliklinika Borzan d.o.o. /ID# 265503, Osijek, Osjecko-baranjska Zupanija

Specialty Hospital Medico /ID# 265504, Rijeka, Primorsko-goranska Zupanija

Klinicki Bolnicki Centar (KBC) Split /ID# 265511, Split, Splitsko-dalmatinska Zupanija

Hepato-Gastroenterologie HK /ID# 265387, Hradec Králové, Hradec Kralove

SurGal Clinic /ID# 265388, Brno, Jihomoravsky Kraj

Iscare Klinické Centrum /ID# 265407, Prague, Praha 9

Medicum /ID# 268304, Tallinn, Harjumaa

East Tallinn Central Hospital /ID# 267658, Tallinn, Not set

Tartu University Hospital /ID# 267656, Tartu, Not set

Chu de Nice-Hopital L'Archet Ii /Id# 267478, Nice, Alpes-Maritimes

Centre Hospitalier Universitaire de Bordeaux /ID# 265721, Pessac CEDEX, Gironde

CHU de Toulouse - Hôpital Rangueil /ID# 267479, Toulouse CEDEX 9, Haute-Garonne

CHU de Montpellier - Hopital Saint Eloi /ID# 265718, Montpellier, Herault

Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou /ID# 266848, Rennes, Ille-et-Vilaine

Centre Hospitalier Universitaire de Saint Etienne - Hopital Nord /ID# 265340, St-Priest-en-Jarez, Loire

CHRU de Nancy-Hopital Brabois Adultes /ID# 265703, Vandoeuvre les Nancy, Lorraine

Hospices Civils de Lyon - Centre Hospitalier Lyon-Sud /ID# 266851, Pierre Benite, Rhone

Clinique Jules Verne /ID# 267480, Nantes, Not set

Hôpital Saint Antoine /ID# 265725, Paris, Not set

Universitaetsklinikum Freiburg /ID# 265755, Freiburg, Baden-Wuerttemberg

Universitaetsmedizin Mannheim /ID# 266961, Mannheim, Baden-Wuerttemberg

Universitaetsklinikum Ulm /ID# 266962, Ulm, Baden-Wuerttemberg

Universitaetsklinikum Erlangen /ID# 265927, Erlangen, Bayern

Markus Krankenhaus /ID# 265938, Frankfurt am Main, Hessen

Universitaetsklinikum Frankfurt /ID# 266827, Frankfurt, Hessen

Klinikum Lueneburg /ID# 266886, Lueneburg, Niedersachsen

St. Marien- und St. Annastiftskrankenhaus /ID# 265912, Ludwigshafen am Rhein, Rheinland-Pfalz

Universitaetsklinikum des Saarlandes /ID# 265753, Homburg, Saarland

Studiengesellschaft BSF Unternehmergesellschaft /ID# 265751, Halle (Saale), Sachsen-Anhalt

Universitaetsklinikum Carl Gustav Carus Dresden /ID# 265931, Dresden, Sachsen

Eugastro /ID# 266826, Leipzig, Sachsen

Universitaetsklinikum Schleswig-Holstein - Campus Kiel /ID# 265738, Kiel, Schleswig-Holstein

Universitaetsklinikum Schleswig-Holstein Campus Luebeck /ID# 267254, Lübeck, Schleswig-Holstein

Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 265752, Berlin, Not set

DRK Kliniken Berlin - Westend /ID# 265925, Berlin, Not set

Krankenhaus Waldfriede /ID# 266676, Berlin, Not set

Debreceni Egyetem-Klinikai Kozpont /ID# 267389, Debrecen, Hajdu-Bihar

Clinfan /ID# 267385, Szekszárd, Tolna

Synexus Hungary Clinical Research Centre - Budapest /ID# 267384, Budapest, Not set

Semmelweis Egyetem /ID# 267064, Budapest, Not set

Semmelweis Egyetem /ID# 267068, Budapest, Not set

Szegedi Tudományegyetem /ID# 267386, Szeged, Not set

Portiuncula University Hospital /ID# 267771, Ballinasloe, Galway

Our Lady of Lourdes Hospital - Drogheda /ID# 267768, Drogheda, Louth

Midland Regional Hospital Mullingar /ID# 267769, Mullingar, Westmeath

St. Vincent's University Hospital /ID# 267766, Dublin, Not set

Beaumont Hospital /ID# 267770, Dublin, Not set

Connolly Hospital /ID# 268021, Dublin, Not set

Soroka Medical Center /ID# 267235, Be'er Sheva, HaDarom

Edith Wolfson Medical Center /ID# 267640, Holon, HaMerkaz

Tel Aviv Sourasky Medical Center /ID# 267307, Tel Aviv, Tel-Aviv

Rambam Health Care Campus /ID# 267641, Haifa, Not set

Azienda Ospedaliero Universitaria di Cagliari - P.O. Duilio Casula /ID# 267287, Monserrato, Cagliari

Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 267143, San Giovanni Rotondo, Foggia

IRCCS Istituto Clinico Humanitas /ID# 265946, Rozzano, Lombardia

IRCCS Ospedale San Raffaele /ID# 265951, Milan, Milano

Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 265935, Rome, Roma

Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 265940, Rome, Roma

A.O. Ordine Mauriziano di Torino /ID# 267144, Turin, Torino

IRCCS Ospedale Sacro Cuore Don Calabria /ID# 265942, Negrar, Verona

Azienda Ospedaliero-Universitaria Renato Dulbecco /ID# 267722, Catanzaro, Not set

Azienda Ospedaliera Universitaria Gaetano Martino /ID# 267145, Messina, Not set

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico /ID# 265949, Milano, Not set

Inje University Haeundae Paik Hospital /ID# 266380, Busan, Busan Gwang Yeogsi

Dong-A University Medical Center /ID# 266709, Busan, Busan Gwang Yeogsi

The Catholic University of Korea, Daejeon St. Mary's Hospital /ID# 265488, Daejeon, Daejeon Gwang Yeogsi

Chungang University Hospital /ID# 266427, Dongjak-gu, Seoul Teugbyeolsi

Samsung Medical Center /ID# 265489, Seoul, Seoul Teugbyeolsi

Kyungpook National University Chilgok Hospital /ID# 265487, Daegu, Not set

Liepaja Regional Hospital /ID# 267703, Liepaja, Not set

Pauls Stradins Clinical University Hospital /ID# 267705, Riga, Not set

Digestive Diseases Center GASTRO /ID# 267707, Riga, Not set

Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 267695, Kaunas, Not set

Panevezys Republican Hospital /ID# 267709, Panevezys, Not set

Vilnius University Hospital Santaros Klinikos /ID# 267711, Vilnius, Not set

Elisabeth TweeSteden Ziekenhuis /ID# 265729, Tilburg, Noord-Brabant

Amsterdam UMC, locatie AMC /ID# 268321, Amsterdam, Noord-Holland

Universitair Medisch Centrum Groningen /ID# 265736, Groningen, Not set

Universitair Medisch Centrum Utrecht /ID# 265731, Utrecht, Not set

Akershus University Hospital /ID# 267642, Lørenskog, Akershus

Helse More- og Romsdal HF, Alesund sjukehus /ID# 267632, Alesund, More Og Romsdal

Oslo Universitetssykehus Ulleval /ID# 267630, Oslo, Not set

NZOZ Centrum Medyczne KERmed /ID# 266766, Bydgoszcz, Kujawsko-pomorskie

Gastromed Sp. z o.o /ID# 266765, Torun, Kujawsko-pomorskie

Malopolskie Centrum Kliniczne /ID# 265943, Krakow, Malopolskie

Medical Network Sp.z.o.o. WIP Warsaw IBD Point Profesor Kierkus /ID# 266764, Warsaw, Mazowieckie

Bodyclinic Sp. z o.o. sp.k. /ID# 265945, Warszawa, Mazowieckie

Endoskopia Sp. z.o.o. /ID# 265934, Sopot, Pomorskie

H-T Centrum Medyczne Endoterapia /ID# 265937, Tychy, Slaskie

Polimedica PTG Kielce /ID# 267066, Kielce, Swietokrzyskie

Unidade Local de Saude do Alto Ave, EPE /ID# 265892, Guimaraes, Braga

2CA-Braga, Hospital de Braga /ID# 265894, Braga, Not set

Unidade Local de Saude de Coimbra, EPE /ID# 267240, Coimbra, Not set

Unidade Local de Saude de Lisboa Ocidental, EPE /ID# 267242, Lisboa, Not set

Unidade Local de Saude de Santa Maria, EPE /ID# 266113, Lisboa, Not set

Unidade Local de Saude do Alto Minho, EPE - Hospital de Santa Luzia /ID# 265885, Viana Do Castelo, Not set

Memorial Healthcare International S.R.L. /Id# 267328, Bucharest, Bucuresti

Spitalul Clinic Colentina /ID# 267208, Bucharest, Bucuresti

Clinica Gastro Med SRL /ID# 267204, Cluj-Napoca, Cluj

OncoHelp Association /ID# 267203, Timișoara, Timis

Clinical Hospital Center Zvezdara /ID# 265605, Belgrade, Beograd

Military Medical Academy /ID# 267452, Belgrade, Beograd

University Clinical Hospital Center "Dr. Dragisa Misovic - Dedinje" /ID# 265607, Belgrade, Beograd

Clinical Hospital Center - Bežanijska Kosa /ID# 265604, Belgrade, Beograd

Leskovac General Hospital /ID# 265606, Leskovac, Jablanicki Okrug

General Hospital Djordje Joanovic /ID# 266040, Zrenjanin, Vojvodina

University Clinical Center Vojvodina /ID# 265603, Novi Sad, Not set

Mount Elizabeth Hospital /ID# 268354, Singapore, Central Singapore

Gleneagles Hospital /ID# 268385, Singapore, Central Singapore

National University Hospital /ID# 268128, Singapore, Not set

Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 266064, Banska Bystrica, Banskobystricky Kraj

KM Management, spol. s.r.o. /ID# 266070, Nitra, Nitriansky Kraj

Gastro I., s.r.o. /ID# 267159, Prešov, Presovsky Kraj

ENDOMED s.r.o /ID# 266068, Košice, Not set

General Hospital Celje /ID# 267699, Celje, Not set

University Medical Centre Ljubljana /ID# 267697, Ljubljana, Not set

Complejo Hospitalario Universitario de Santiago (CHUS) /ID# 266902, Santiago de Compostela, A Coruna

Hospital Universitario Virgen Macarena /ID# 266648, Seville, Sevilla

Hospital Universitario Virgen del Rocio /ID# 266727, Seville, Sevilla

Hospital Clinic de Barcelona /ID# 265415, Barcelona, Not set

Hospital Universitario 12 de Octubre /ID# 265444, Madrid, Not set

Hospital Universitario La Paz /ID# 265412, Madrid, Not set

Hospital Alvaro Cunqueiro /ID# 266647, Pontevedra, Not set

Hospital Universitari i Politècnic La Fe /ID# 265478, Valencia, Not set

Intesto /ID# 265728, Bern, Not set

Western General Hospital - NHS Lothian /ID# 266333, Edinburgh, Edinburgh, City Of

Gartnavel General Hospital /ID# 266407, Glasgow, Glasgow City

Royal Free Hospital /ID# 268065, London, Greater London

Guy's Hospital /ID# 266336, London, Greater London

St George's University Hospitals NHS Foundation Trust /ID# 266335, London, Greater London

The John Radcliffe Hospital /ID# 266334, Oxford, Oxfordshire

The Royal Wolverhampton NHS Trust /ID# 268158, Guildford, Surrey

University Hospital Coventry & Warwickshire NHS Trust /ID# 267128, Coventry, Warwickshire

Barts Health NHS Trust /ID# 266410, London, Not set

Royal Victoria Infirmary /ID# 268064, Newcastle upon Tyne, Not set

Conditions: Crohn's Disease

Learn More ›

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

NCT06699849

Recruiting

This study consists of two parts: phase 2 (Part A) and phase 3 (Part B). It is a multicenter study designed to evaluate the safety, effectiveness, and pharmacokinetics (PK) of CSL889 (human hemopexin) when given intravenously (IV) to adults and adolescents with sickle cell disease (SCD) experiencing vaso-occlusive crises (VOC). The main objectives of the study are to assess how CSL889 affects the time it takes for VOC to resolve in participants with SCD, and to evaluate the safety and tolerabili... Read More

Gender:

ALL

Ages:

12 years and above

Trial Updated:

08/18/2025

Locations: University of California Irvine, Orange, California +15 locations

Conditions: Sickle Cell Disease Vaso-occlusive Crisis

Learn More ›

A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

NCT06747585

Recruiting

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic, pharmacodynamic, preliminary anti-tumor activity, and to determine the recommended Phase II dose (RP2D) of the ALE.P02 monotherapy in adult patients with selected squamous solid tumors.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Providence Medical Foundation, Fullerton, California +23 locations

Providence Medical Foundation, Fullerton, California

USC Norris Comprehensive Cancer Center, Los Angeles, California

Yale Comprehensive Cancer Center, New Haven, Connecticut

Norton Cancer Institue Downtown, Louisville, Kentucky

Hackensack University Medical Center, Hackensack, New Jersey

NEXT Oncology Virginia, Fairfax, Virginia

Institut Gustave Roussy, Villejuif, Not set

Chinese University of Hong Kong - Prince of Wales Hospital, Shatin, N.t.

Ospedale San Raffaele, IRCCS, Milano, Not set

IEO - Istituto Europeo di Oncologia, IRCCS, Milano, Not set

PU A. Gemelli, Universita Cattolica del Sacro Cuore, Roma, Not set

Centro Ricerche Cliniche Verona, Verona, Not set

National University Cancer Institue, Singapore, South West

National Cancer Centre Singapore, Singapore, South West

Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón, Madrid

START Madrid- Centro Integral Oncologico Clara Campal, Sanchinarro, Madrid

Hospital Universitari Vall D Hebron, Barcelona, Not set

START Hospital HM Nou Delfos, Barcelona, Not set

Hospital Universitario Virgen De La Victoria, Málaga, Not set

Hospital Universitario Y Politécnico La Fe, Valencia, Not set

Changhua Christian Medical Foundation Changhua Christian Hospital, Changhua, Not set

National Taiwan University Hospital, Taipei, Not set

Buddihist Tzu Chi Medical Foundation - Taipei Tzu Chi Hospital, Taipei, Not set

Conditions: Squamous Non-small-cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Cervical Squamous Cell Carcinoma, Esophageal Squamous Cell Carcinoma

Learn More ›

Brief Intervention for Chronic Pain and History of Stressful Experiences

NCT06983327

Recruiting

The goal of this study is to understand whether a brief, three session program can be helpful in reducing symptoms related to both chronic pain and stressful experiences/trauma.

Gender:

ALL

Ages:

21 years and above

Trial Updated:

08/18/2025

Locations: Brigham and Women's Hospital, Chestnut Hill, Massachusetts

Conditions: Chronic Pain, Trauma, Adverse Childhood Experiences

Learn More ›

A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)

NCT06924970

Recruiting

The main purpose of this study is to compare the effect of tebapivat versus placebo on anemia and to detect a dose-response for hemoglobin (Hb) response in participants with SCD.

Gender:

ALL

Ages:

16 years and above

Trial Updated:

08/18/2025

Locations: MedStar Washington Hospital Center, Washington, District of Columbia +2 locations

Conditions: Sickle Cell Disease

Learn More ›

Study of 225Ac-ABD147 to Establish Optimal Dose in Patients With SCLC and LCNEC of the Lung That Previously Received Platinum-based Chemotherapy

NCT06736418

Recruiting

The study has 2 parts, Phase 1a and Phase 1b. The goal of Phase 1a is to gather safety, PK and initial efficacy data for 225Ac-ABD147 to better understand best doses for patients with small cell lung cancer (SCLC) and large cell neuroendocrine carcinoma (LCNEC) of the lung following platinum-based chemotherapy. An initial group of patients will also be given an experimental imaging agent called 111In-ABD147 to help understand where ABD147 goes in the body. The goal of Phase 1b is to gather add... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Hoag Memorial Hospital Presbyterian, Newport Beach, California +4 locations

Conditions: Small-Cell Lung Cancer (SCLC), Large Cell Neuroendocrine Carcinoma of the Lung

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A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)

NCT06140836

Recruiting

The purpose of this study is to evaluate the efficacy and safety of repotrectinib and crizotinib in participants with locally advanced or metastatic TKI-naïve ROS1-positive non-small cell lung cancer (NSCLC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Local Institution - 0136, Augusta, Georgia +143 locations

Local Institution - 0136, Augusta, Georgia

Local Institution - 0221, Des Moines, Iowa

Massachusetts General Hospital, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Local Institution - 0217, Brooklyn, New York

Perlmutter Cancer Center at NYU Langone Hospital - Long Island, Mineola, New York

Laura and Isaac Perlmutter Cancer Center, New York, New York

Local Institution - 0127, Syracuse, New York

Local Institution - 0214, Tacoma, Washington

Local Institution - 0061, Milwaukee, Wisconsin

Local Institution - 0092, Ciudad autónoma de Buenos Aires, Buenos Aires

Instituto Alexander Fleming, Ciudad Autónoma de Buenos Aires, Buenos Aires

Local Institution - 0091, ABB, Ciudad Autónoma De Buenos Aires

Local Institution - 0106, Buenos Aires, Not set

Local Institution - 0207, Buenos Aires, Not set

Instituto Oncológico de Córdoba, Córdoba, Not set

Local Institution - 0041, Wien, Not set

Local Institution - 0073, Belo Horizonte, Minas Gerais

Local Institution - 0033, Porto Alegre, Rio Grande Do Sul

Local Institution - 0034, Porto Alegre, Rio Grande Do Sul

Local Institution - 0029, Barretos, São Paulo

Local Institution - 0209, Sao Paulo, São Paulo

Local Institution - 0147, Sao Paulo, São Paulo

Local Institution - 0037, São José do Rio Preto, São Paulo

Local Institution - 0098, Rio de Janeiro, Not set

Local Institution - 0108, Rio de Janeiro, Not set

Local Institution - 0032, São Paulo, Not set

Local Institution - 0114, São Paulo, Not set

Local Institution - 0002, Toronto, Ontario

Local Institution - 0123, Trois-Rivières, Quebec

Fundacion Arturo Lopez Perez (FALP), Santiago, Región Metropolitana De Santiago

Oncocentro Apys, Viña del Mar, Valparaíso

Local Institution - 0168, Beijing, Beijing

Local Institution - 0185, Chongqing, Chongqing

Local Institution - 0192, Fuzhou, Fujian

Local Institution - 0169, Xiamen, Fujian

Local Institution - 0180, Guangzhou, Guangdong

Local Institution - 0194, Nanning, Guangxi

Local Institution - 0171, Harbin, Heilongjiang

Local Institution - 0166, Zhengzhou, Henan

Local Institution - 0181, Wuhan Shi, Hubei

Local Institution - 0203, Wuhan, Hubei

Local Institution - 0184, Changsha, Hunan

Local Institution - 0165, Changsha, Hunan

Local Institution - 0193, Nanjing, Jiangsu

Local Institution - 0202, Nanchang, Jiangxi

Local Institution - 0178, Changchun, Jilin

Local Institution - 0183, Xi'an, Shaanxi

Local Institution - 0186, Jinan, Shandong

Local Institution - 0205, Linyi, Shandong

Local Institution - 0164, Shanghai, Shanghai

Local Institution - 0179, Shanghai, Shanghai

Local Institution - 0170, Chengdu, Sichuan

Local Institution - 0177, Chengdu, Sichuan

Local Institution - 0204, Kunming, Yunnan

Local Institution - 0206, Hangzhou, Zhejiang

Local Institution - 0175, Hangzhou, Zhejiang

Nouvel Hôpital Civil (NHC), Strasbourg, Alsace

CHU Bordeaux Haut-Leveque, Pessac, Aquitaine

Centre Georges François Leclerc, Dijon, Côte-d'Or

CHU Charles Nicolle, Rouen, Haute-Normandie

Chu Grenoble Alpes, La Tronche, Isère

Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes, Saint-Herblain, Loire-Atlantique

Centre Hospitalier Lyon Sud, Pierre-Bénite, Rhône

Hopitaux Universitaires Paris Centre-Hopital Cochin, Paris, Not set

Klinikum Esslingen, Esslingen, Baden-Württemberg

Klinikum Würzburg Mitte, Wuerzburg, Bayern

Pius Hospital Oldenburg, Oldenburg, Niedersachsen

Evangelische Lungenklinik Berlin, Berlin, Not set

Local Institution - 0035, Dresden, Not set

Asklepios Klinik Gauting GmbH, Gauting, Not set

Lungenfachklinik Immenhausen, Immenhausen, Not set

Universitaetsklinikum Koeln, Köln, Not set

Marienhaus Klinikum Mainz, Mainz, Not set

University Hospital of Patras, Patras, Achaḯa

Local Institution - 0153, Athens, Attikí

Local Institution - 0155, Chaidari, Attikí

"Theagenio" Cancer Hospital of Thessaloniki, Thessaloniki, Kentrikí Makedonía

Országos Korányi Pulmonológiai Intézet, Budapest, Not set

All India Institute of Medical Sciences, New Delhi, Delhi

Rajiv Gandhi Cancer Institute And Research Centre, New Delhi, Delhi

Hemato Oncology Clinic, Ahmedabad, Gujarat

HCG Aastha Cancer Centre, Ahmedabad, Gujarat

Local Institution - 0117, Gurgaon, Haryana

Artemis hospital, Gurugram, Haryana

Manipal Hospitals, Bengaluru, Karnataka

Local Institution - 0219, Thiruvananthapuram, Kerala

Local Institution - 0065, Mumbai, Maharashtra

Local Institution - 0048, Mumbai, Maharashtra

Grant Medical Foundation - Ruby Hall Clinic, Pune, Maharashtra

Sahyadri Super Speciality Hospital, Pune, Maharashtra

Local Institution - 0220, Hyderabad, Telangana

Cro-Irccs, Aviano, Friuli-Venezia Giulia

Local Institution - 0152, Milan, Lombardia

Fondazione IRCCS San Gerardo dei Tintori, Monza, Lombardia

A.O.R.N. Ospedale dei Colli - Monaldi V., Naples, Napoli

Local Institution - 0148, Rome, Roma

Nagoya University Hospital, Nagoya, Aichi

National Cancer Center Hospital East, Kashiwa, Chiba

Local Institution - 0174, Matsuyama-shi, Ehime

Hokkaido University Hospital, Sapporo, Hokkaido

Kanagawa cancer center, Yokohama, Kanagawa

Sendai Kosei Hospital, Sendai, Miyagi

Tokyo Metropolitan Komagome Hospital, Bunkyo ku, Tokyo

Tottori University Hospital, Yonago, Tottori

Local Institution - 0195, Fukuoka, Not set

Osaka City General Hospital, Osaka, Not set

Osaka International Cancer Institute, Osaka, Not set

Tokyo Metropolitan Police Hospital, Tokyo, Not set

Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do [Chungbuk]

Seoul National University Bundang Hospital, Seongnam, Kyǒnggi-do

Severance Hospital, Yonsei University Health System, Seoul, Seoul-teukbyeolsi [Seoul]

Asan Medical Center, Seoul, Seoul-teukbyeolsi [Seoul]

Samsung Medical Center, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0223, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur

Local Institution - 0237, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur

Local Institution - 0222, Lembah Pantai, Wilayah Persekutuan Kuala Lumpur

Local Institution - 0226, Lembah Pantai, Wilayah Persekutuan Kuala Lumpur

Local Institution - 0224, Putrajaya, Wilayah Persekutuan Kuala Lumpur

Amsterdam UMC, locatie VUmc, Amsterdam, Noord-Holland

Local Institution - 0215, Groningen, Not set

Local Institution - 0187, Lublin, Lubelskie

Warmińsko - Mazurskie Centrum Chorób Płuc w Olsztynie, Olsztyn, Warmińsko-mazurskie

SC Memorial Healthcare International SRL, Bucharest, București

Institutul Oncologic Bucuresti, Bucharest, București

Centrul de Oncologie "Sfântul Nectarie", Craiova, Dolj

Institutul Oncologic Cluj, Cluj, Not set

S.C. Centrul de Oncologie Euroclinic S.R.L., Iași, Not set

CHUAC-Hospital Teresa Herrera, A Coruña, A Coruña [La Coruña]

CHUS - Hospital Clinico Universitario, Santiago de Compostela, A Coruña [La Coruña]

Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]

Hospital Universitario 12 de Octubre, Madrid, Madrid, Comunidad De

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid, Comunidad De

H.R.U Málaga - Hospital General, Málaga, Not set

Hospital Universitario Virgen Del Rocio, Sevilla, Not set

Hospital Universitari i Politecnic La Fe, València, Not set

Kantonspital Baden, Baden, Aargau

Ankara Bilkent Şehir Hastanesi, Yenimahalle, Ankara

Adana Medical Park Seyhan Hastanesi, Adana, Not set

Sbü Gülhane Eğitim Ve Araştirma Hastanesi, Ankara, Not set

Medipol Mega Universite Hastanesi, Istanbul, Not set

T.C. Saglik Bakanligi Turkiye Kamu Hastaneleri Kurumu - Bakirkoy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi, Istanbul, Not set

VM Medical Park Pendik Hospital, Istanbul, Not set

Sakarya Training and Research Hospital, Sakarya, Not set

Conditions: Carcinoma, Non-Small-Cell Lung

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A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130850 in Participants With Advanced Solid and Hematologic Tumors

NCT06188208

Recruiting

A FIH study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of VVD-130850, as single agent and in combination with checkpoint inhibition, in participants with advanced solid and hematologic tumors.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: California Research Institute, Los Angeles, California +19 locations

Conditions: Advanced Solid Tumors, Advanced Hematologic Tumors

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A Study of PARP1 Selective Inhibitor, EIK1004 (IMP1707) in Participants With Advanced Solid Tumors.

NCT06907043

Recruiting

This study will evaluate the safety, tolerability, and preliminary efficacy of EIK1004 (IMP1707) in participants with recurrent advanced/metastatic breast cancer, ovarian cancer, metastatic castrate resistant prostate cancer (mCRPC) and pancreatic cancer with deleterious/suspected deleterious mutations of select homologous recombination repair (HRR) genes. Condition or disease Intervention/treatment Phase Advanced Solid Tumors Drug: EIK1004 (IMP1707) Phase 1/Phase 2

Gender:

ALL

Ages:

Between 18 years and 89 years

Trial Updated:

08/18/2025

Locations: Sarah Cannon Research Institute at HealthOne, Denver, Colorado +9 locations

Conditions: Advanced Solid Tumors

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An Open Label Dose Escalation Study to Assess the Safety, Tolerability, and Pharmacologic Properties of High Dose Ambroxol Hydrochloride in Adult (≥ 18 Years of Age) Subjects With MPS III

NCT06614894

Recruiting

A dose escalation study to evaluate the safety, tolerability, and pharmacologic properties of Ambroxol in adult participants with Sanfilippo disease(s) (MPS3).

Gender:

ALL

Ages:

Between 18 years and 99 years

Trial Updated:

08/18/2025

Locations: Lysosomal & Rare Disorders Research & Treatment Center, Inc., Fairfax, Virginia

Conditions: Sanfilippo Syndrome, MPS3

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