Technology Exposure and Child Health: Wellness Impact and Social Effects: an Observational Product Registry Study
Recruiting
The goal of this study is to understand how children's mobile device usage (smartphones or tablets), including social media use and online games, are related to their mental wellness and mental health, as well as some aspects of their physical activity and sleep. This study is available to all children between the ages of 8 and 17 years and a parent/caregiver. Researchers will compare participant mobile device usage with their survey responses on sleep, stress, mental health, and physical activ... Read More
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
02/01/2025
Locations: Aura, Boston, Massachusetts
Conditions: Mood, Depression Disorders, Anxiety Disorders, Sleep, Eating Disorders, Physical Activity, Loneliness, Stress
Infusion of Cell Populations From Unlicensed Umbilical Cord Blood Units
Recruiting
For the next 5-10 years or possibly longer, a high proportion of the Cord Blood Banks (CBB) inventory worldwide will be composed of unlicensed umbilical cord blood (UCB) units. While Food and Drug Administration (FDA)-licensed units will be prioritized, it will always be possible that an unlicensed unit will have known attributes, making it a better source of cells for the given indication. Because of the wide variety of current and potential indications as a source of cells for hematopoietic re... Read More
Gender:
ALL
Ages:
All
Trial Updated:
01/31/2025
Locations: Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota
Conditions: Lymphatic Diseases, Hematopoietic Malignancy
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
Recruiting
This is a standard of care treatment guideline for allogeneic hematopoetic stem cell transplant (HSCT) in patients with primary immune deficiencies.
Gender:
ALL
Ages:
50 years and below
Trial Updated:
01/31/2025
Locations: Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota
Conditions: SCID, Omenn's Syndrome, Reticular Dysgenesis, Wiskott-Aldrich Syndrome, Bare Lymphocyte Syndrome, Common Variable Immunodeficiency, Chronic Granulomatous Disease, CD40 Ligand Deficiency, Hyper IgM Syndrome, X-linked Lymphoproliferative Disease, Hemophagocytic Lymphohistiocytosis, Griscelli Syndrome, Chediak-Higashi Syndrome, Langerhan's Cell Histiocytosis
Study of Placental Function in Healthy and Pathological Pregnancies
Recruiting
The purpose of this study is to establish a tissue and data repository consisting of samples of human placentas, umbilical cord blood, and maternal blood, collected at the time of delivery. Specimens will be used in cellular, molecular, and functional studies to learn more about changes in placental structure and function, which can result in serious pregnancy complications and determine life-long health by programming the fetus for future metabolic and cardiovascular disease.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
01/31/2025
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Pregnancy
EDRN Prostate MRI Biomarker Study
Recruiting
The commercialization of MRI fusion biopsies has resulted in a dramatic increase in the use of MRI imaging for prostate cancer. How best to use MRI in the initial prostate biopsy setting given the availability of validated prostate cancer early detection markers is uncertain.This study will allow investigators to determine if prostate MRI is superior to validated panel of laboratory biomarkers (e.g. PCA3, PSA and TMPRSS2:ERG) in the initial biopsy setting.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: PSA, Prostate Cancer
Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study
Recruiting
The objective of this study is to examine photos of CCCA patients taken before and after treatment to compare treatment outcomes between different treatment groups
Gender:
FEMALE
Ages:
Between 18 years and 60 years
Trial Updated:
01/31/2025
Locations: Wake Forest Baptist Health Department of Dermatology, Winston-Salem, North Carolina
Conditions: Central Centrifugal Cicatricial Alopecia (CCCA)
Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting
Recruiting
Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy. The purpose of this study is to test the safety and feasibility of these transplant technologies and restore fertility for these participants.
Gender:
MALE
Ages:
All
Trial Updated:
01/31/2025
Locations: Magee-Womens Hospital, Pittsburgh, Pennsylvania
Conditions: Infertility, Male, Cancer, Autoimmune Disorder
Video Telehealth Exercise Training in Cystic Fibrosis
Recruiting
The purpose of this research study is to begin an exercise program for patients with a cystic fibrosis (CF) exacerbation.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
01/31/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cystic Fibrosis
Establishing a Tumor Registry for Patients With Neuroendocrine Carcinoma of the Cervix
Recruiting
This study collects information and data on patients with neuroendocrine cervical cancer. Information from this study may be used to better understand the correlation between clinical data, such as patient characteristics, treatment, and disease outcomes, and overall patient outcomes.
Gender:
ALL
Ages:
All
Trial Updated:
01/31/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Cervical Large Cell Neuroendocrine Carcinoma, Cervical Neuroendocrine Carcinoma, Cervical Small Cell Carcinoma, Cervical Undifferentiated Carcinoma, Stage I Cervical Cancer AJCC v8, Stage IA Cervical Cancer AJCC v8, Stage IA1 Cervical Cancer AJCC v8, Stage IA2 Cervical Cancer AJCC v8, Stage IB Cervical Cancer AJCC v8, Stage IB1 Cervical Cancer AJCC v8, Stage IB2 Cervical Cancer AJCC v8, Stage II Cervical Cancer AJCC v8, Stage IIA Cervical Cancer AJCC v8, Stage IIA1 Cervical Cancer AJCC v8, Stage IIA2 Cervical Cancer AJCC v8, Stage IIB Cervical Cancer AJCC v8, Stage III Cervical Cancer AJCC v8, Stage IIIA Cervical Cancer AJCC v8, Stage IIIB Cervical Cancer AJCC v8, Stage IV Cervical Cancer AJCC v8, Stage IVA Cervical Cancer AJCC v8, Stage IVB Cervical Cancer AJCC v8
Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy
Recruiting
The purpose of this Phase 3 study is to determine whether iptacopan (LNP023) is efficacious and safe for the treatment of aHUS in adult patients who are treatment naive to complement inhibitor therapy.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/31/2025
Locations: Uni Of Alabama At Birmingham, Birmingham, Alabama +67 locations
Conditions: Atypical Hemolytic Uremic Syndrome
Urban and Reservation Implementation of All Nations Breath of Life
Recruiting
This is an implementation trial of the All Nations Breath of Life (ANBL) smoking cessation program, which has already been tested for efficacy in reservation populations and shown feasibility in urban populations. It includes four implementation sites, two reservation sites and two urban sites. Therefore, investigators plan to test efficacy simultaneously. Implementation will follow guidelines described in the protocol, with all sites implementing certain parts of the intervention the same way,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: Lehigh University, Bethlehem, Pennsylvania
Conditions: Smoking Cessation
Metabolic Diet for Relapse Prevention in Anorexia Nervosa
Recruiting
This is an interventional study that will test the safety, tolerability, and efficacy of the Metabolic Diet, which was designed as a treatment for women with anorexia nervosa to remain weight-stable after they have been restored from low weight. Participants will be adult women with anorexia nervosa who have been recently restored to normal weight and adult women with no history of eating disorders. After enrollment, participants will start meeting weekly with a registered dietitian to implement... Read More
Gender:
FEMALE
Ages:
Between 18 years and 40 years
Trial Updated:
01/31/2025
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Anorexia Nervosa