Transvaginal Versus Fluoroscopy-guided Trans Gluteal Pudendal Nerve Block for Pudendal Neuralgia
NCT06644261
Recruiting
Chronic pain affecting the pelvic and urogenital area is a major clinical problem and can have a profound impact on quality of life and health care costs. Pelvic pain arising from entrapment or neuropathy of the pudendal nerve is known as pudendal neuralgia, which results in chronic perineal pain. This pain syndrome is difficult to diagnose and patients with pudendal neuralgia may present to providers with refractory chronic pelvic pain. Pudendal nerve infiltration or pudendal nerve block (PNB)... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: University of Louisville Division of Urogynecology and Reconstructive Pelvic Surgery, Louisville, Kentucky
Conditions: Pudendal Neuralgia, Chronic Pelvic Pain Syndrome
Register for Updates
Enhancing Preventative Health Behaviors Among Emergency Department Hyperglycemic Patients
NCT06663813
Recruiting
The goal of this clinical trial is to increase Type 2 Diabetes Mellitus knowledge and awareness among patients who present to the Emergency Department with hyperglycemia. The main questions it aims to answer are: * How do patients view their risk of developing type 2 diabetes based on their demographics and behaviors? * Does giving patient education increase patient knowledge, leading to healthier behaviors? Researchers will assess if the educational intervention increases diabetes knowledge a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: One Robert Wood Johnson Place, New Brunswick, New Jersey +1 locations
Conditions: Type 2 Diabetes, Hyperglycemia
Register for Updates
Evaluation of a Health System Integrated Model for Postpartum Education and Support in Rural Populations
NCT06682520
Recruiting
This study was designed to evaluate the implementation of the Nurse Education and Support Team (NEST) Program for postpartum women who reside in 5 rural counties in North Carolina. Overarching Hypothesis: Mothers and infants residing in rural communities, randomized to the NEST-Rural care model over the 3-year course of the project will: 1. Receive more coordinated care for addressing social, mental and physical health needs. 2. Experience fewer postpartum hospital readmissions and decreased uti... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina
Conditions: Health Care Utilization
Register for Updates
Relative Bioavailability of NX-5948 Tablets Vs Capsules and the Effect of Covariates on the PK of NX-5948 Tablets
NCT06717269
Recruiting
This is a 2-cohort, fixed-sequence, 3-period, relative bioavailability, food-effect, and drug-drug interaction study. It is an open-label study evaluating the relative bioavailability of NX-5948 tablets compared to capsules, and the effect of food and an acid-reducing agent on the pharmacokinetics (PK) of NX-5948.
Gender:
ALL
Ages:
Between 19 years and 55 years
Trial Updated:
12/13/2024
Locations: Celerion, Lincoln, Nebraska
Conditions: Healthy Volunteer
Register for Updates
Assessing the Relationship Between Symptoms and Mitral Regurgitnant. Severity
NCT06738615
Recruiting
The current American College of Cardiology/American Heart Association (ACC/AHA) guidelines recommend surgery in patient with mitral regurgitation (MR) based on 1) the severity of MR and 2) the presence or absence of symptoms. Studies have shown that Cardiovascular Magnetic Resonance (CMR) is an accurate method to quantify the severity of MR. However, studies have also shown that symptoms are not necessarily related to the presence of symptoms. Thus, there appears to be a disconnect between the s... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: Morristown Medical Center, Morristown, New Jersey
Conditions: Mitral Insufficiency
Register for Updates
The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families
NCT06740266
Recruiting
The goal of this clinical trial study is to learn how stress in childhood, or Early Life Adversity (ELA), gets "under the skin" and influences long-term health. The investigators will test if the support given to parents of young children reduces childhood stress. The investigators will also test if the effects of mother's stress and Early Life Adversity can be passed down to children. Can it impact the child's long-term health? Researchers will compare the Promoting First Relationships® in Prim... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: WakeMed Health & Hospitals, Raleigh, North Carolina
Conditions: Parent Child Relationship, Child Social-Emotional Development, Telomere Length, Epigenetic Aging
Register for Updates
Assessment of Quizartinib Pharmacokinetic in Subjects With Severe Hepatic Impairment
NCT06740799
Recruiting
This study will evaluate and compare the PK in subjects with severe HI to that of matched healthy control subjects with normal hepatic function.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
12/13/2024
Locations: Clinical Pharmacology of Miami, LLC, Miami, Florida +2 locations
Conditions: Hepatic Impairment
Register for Updates
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
NCT03511118
Recruiting
Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently taking, as part of your medical care, at least one of the drugs we are studying. We are interested in studying drugs commonly prescribed to women who are breastfeeding so we can learn more about the amount of drug that is transferred to breastmilk and estimate how much of drug that is consumed by bre... Read More
Gender:
ALL
Ages:
All
Trial Updated:
12/12/2024
Locations: University of California-San Diego Medical Center, La Jolla, California +21 locations
Conditions: Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI
Register for Updates
Natural History, Diagnosis, and Outcomes for Leukodystrophies
NCT03639285
Recruiting
The goals of this protocol is to diagnose, care for, and understand the clinical histories and outcomes of people with leukodystrophies.
Gender:
ALL
Ages:
All
Trial Updated:
12/12/2024
Locations: Primary Children's Hospital, Salt Lake City, Utah
Conditions: Leukodystrophy
Register for Updates
Efficacy and Safety of Cariprazine in the Treatment of Adolescent Participants (13 to 17 Years of Age) With Schizophrenia
NCT03817502
Recruiting
The purpose of this study is to evaluate the efficacy and safety of cariprazine in the treatment of schizophrenia in the adolescent population.
Gender:
ALL
Ages:
Between 13 years and 17 years
Trial Updated:
12/12/2024
Locations: ProScience Research Group, Culver City, California +56 locations
Conditions: Schizophrenia
Register for Updates
Post-market Study of the Biodesign Hernia Graft
NCT04294446
Recruiting
The purpose of this study is to collect data on the performance of the Biodesign® Hernia Graft when used to reinforce soft tissues during ventral hernia repair.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/12/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee +2 locations
Conditions: Ventral Hernia
Register for Updates
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry
NCT04496687
Recruiting
The aim of "iSCAD," the International Spontaneous Coronary Artery Dissection (SCAD) Registry, is to serve as an internationally collaborative, multicenter registry coordinated by an experienced and centralized coordinating center in an effort to increase the pace of participant recruitment, and thereby increase statistical power of studies related to SCAD. The ultimate goal of iSCAD Registry is to facilitate the development of best practices and clinical guidelines for preventing SCAD or its re... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/12/2024
Locations: Cedars Sinai, Los Angeles, California +30 locations
Conditions: Spontaneous Coronary Artery Dissection
Register for Updates