Closed Loop Context Aware AID
NCT06676657
Recruiting
An artificial pancreas (AP) is a control system for automatic insulin delivery. The investigators have implemented a high blood sugar detection and dosing algorithm for use within an AP control system. If a high blood sugar pattern is detected, correction insulin will be calculated and delivered. The investigators will test how well the new algorithm manages glucose compared to the AP control system without high blood sugar detection and dosing. This type of algorithm may improve glucose control... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
11/22/2024
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Type 1 Diabetes
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Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail Approach
NCT06693960
Recruiting
The purpose of this clinical trial is to determine how the supplement oregano affects how the body metabolizes pharmaceutical drugs.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
11/22/2024
Locations: Washington State University College of Pharmacy and Pharmaceutical Sciences, Spokane, Washington
Conditions: Interaction
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Working Memory Training for People Aging with HIV
NCT06699927
Recruiting
The present study investigates the feasibility of working memory training in people aging with HIV (PAWHIV). In a cross-over design this stage 1 feasibility trial, will evaluate acceptability, and estimate possible effect sizes related to working memory training by examining potential differential effects in PAWHIV and those aging without HIV. This project highlights the importance of tailored cognitive assessments and interventions, engaging with underrepresented communities to enhance inclusiv... Read More
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
11/22/2024
Locations: Northeastern University, Boston, Massachusetts
Conditions: Cognitive Change
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SCM Muscle as a Marker for Frailty in Patients Undergoing ENT Surgery
NCT06704256
Recruiting
This study focuses on evaluating the relationship between physical frailty and measurements of the muscles of the neck in patients undergoing non-cancer Head and Neck surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: Mount Sinai Hospital, New York, New York
Conditions: Frailty
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Prostate Ablation Registry and Database for Information, Surveillance, and Evaluation (PARADISE)
NCT06705803
Recruiting
Prostate cancer (PCa) is the most commonly diagnosed non-cutaneous cancer of men in the world. In 2023 alone, it is estimated that 288,300 US men will be diagnosed with prostate cancer and 34,700 will die from the disease despite the approval of multiple systemic agents. Due to advances in screening and imaging technology, PCa is now detected much earlier in its disease course. Prostate gland ablation for prostate cancer might provide the option for a "middle" ground between active surveillance... Read More
Gender:
MALE
Ages:
22 years and above
Trial Updated:
11/22/2024
Locations: The University of Chicago, Hyde Park, Illinois +1 locations
Conditions: Prostate Cancer
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Motivation for Exercise: a Mood-Based Focus
NCT06706180
Recruiting
The goal of this study is to assess the effects of an exercise-related video on exercise motivation and adherence. Specifically, the researchers are studying whether an exercise-for-mood video increase levels of exercise motivation as compared to an exercise-for-fitness video.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: Boston University, Boston, Massachusetts
Conditions: Exercise Motivation
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Quantitative Ultrasound to Assess Steatotic Liver Disease in Children
NCT06706856
Recruiting
This research study is being conducted to find out more about advanced ultrasound techniques to non-invasively evaluate liver disease in children. The investigators are developing advanced techniques for analyzing ultrasound data and images of the liver, and they will compare it to other established methods used to evaluate the liver, including liver MRI. The investigators plan to develop and test the advanced analysis techniques using conventional full-size ultrasound machines and, if possible... Read More
Gender:
ALL
Ages:
Between 9 years and 18 years
Trial Updated:
11/22/2024
Locations: University of California San Diego, La Jolla, California
Conditions: MASLD, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
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Child to Adult Neurodevelopment in Gene Expanded Huntington's Disease
NCT01860339
Recruiting
Huntington's Disease (HD) is an autosomal dominant disease manifested in a triad of cognitive, psychiatric, and motor signs and symptoms. HD is caused by a triplet repeat (CAG)expansion in the gene Huntingtin (HTT). This disease has classically been conceptualized as a neurodegenerative disease. However, recent evidence suggests that abnormal brain development may play an important role in the etiology of HD. Huntingtin (HTT)is expressed during development and through life. In animal studies, th... Read More
Gender:
ALL
Ages:
Between 6 years and 30 years
Trial Updated:
11/21/2024
Locations: University of California Davis, Sacramento, California +5 locations
Conditions: Huntington's Disease
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International Registry for Men With Advanced Prostate Cancer (IRONMAN)
NCT03151629
Recruiting
Our intent is to establish the International Registry to Improve Outcomes in Men with Advanced Prostate Cancer (IRONMAN) as a prospective, international cohort of minimum 5,000 men with advanced cancer, including men with mHSPC and M0/M1 CRPC. The goal is to establish a population-based registry and recruit patients across academic and community practices from Australia, Barbados, Brazil, Canada, Ireland, Jamaica, Kenya, Nigeria, Norway, Spain, South Africa, Sweden, Switzerland, the United Kingd... Read More
Gender:
MALE
Ages:
21 years and above
Trial Updated:
11/21/2024
Locations: University of Alabama-Birmingham, Birmingham, Alabama +120 locations
Conditions: Prostate Cancer
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Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke
NCT03401762
Recruiting
The purpose of the study is to explore the feasibility of using a wearable device, called a myoelectric-computer interface (MCI), to improve arm movement in people who have had a stroke. Impaired arm movement after stroke is caused not just by weakness, but also by impaired coordination between joints due to abnormal co-activation of muscles. These abnormal co-activation patterns are thought to be due to abnormal movement planning.The MCI aims to reduce abnormal co-activation by providing feedb... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/21/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Stroke, Stroke, Acute
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Comparing Effectiveness of Duloxetine and Desipramine in Patients With Chronic Pain: A Pragmatic Trial Using Point of Care Randomization
NCT03548454
Recruiting
Over 100 million Americans suffer from chronic pain resulting in annual cost of roughly $635 billion. Limited treatments are available for this widespread disease. The data supporting these treatments lack generalizability to patients with more serious medical and psychological comorbidities who are often excluded from explanatory efficacy trials. Our work aims to integrate randomized comparative effectiveness research with patient care. The investigators will randomize the patients and collect... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Stanford Pain Management Center, Redwood City, California
Conditions: Chronic Pain
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HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM
NCT03596086
Recruiting
Study to assess the safety and efficacy of HSV-tk (gene therapy), valacyclovir, radiotherapy and chemotherapy in recurrent glioblastoma multiforme.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Houston Methodist Neurological Institute, Houston, Texas
Conditions: Glioblastoma Multiforme, Astrocytoma, Grade III
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