Faith in Action! A Church-Based Navigation Model to Increase Breast Cancer Screening in Korean Women
NCT05298605
Recruiting
The purpose of this research is to develop a culturally adapted "Faith in Action!" curriculum to train lay health navigators to provide breast cancer screening navigation to Korean American women within faith-based settings and evaluate whether the culturally adapted "Faith in Action!" curriculum increases adherence to breast cancer screening guidelines among Korean American women within faith-based settings in Los Angeles, California. The primary research procedures include trainings and key in... Read More
Gender:
FEMALE
Ages:
Between 45 years and 80 years
Trial Updated:
08/23/2024
Locations: Cedars-Sinai Medical Center, Los Angeles, California +1 locations
Conditions: Breast Cancer Female, Health Knowledge, Attitudes, Practice, Cancer Screening, Health Disparities
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Feasibility of Remote Activity Assessment and PRO Collection Among Transgender Cancer Survivors
NCT05391217
Recruiting
Prospective observational feasibility study to evaluate the role of wearable activity monitors to determine the feasibility and acceptability of remote monitoring using wearable technology and PROs to monitor fatigue and physical function in transgender cancer patients and survivors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/23/2024
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Neoplasms, Chronic Disease
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An Immediate Functional Progression Program for Adolescent Athletes With Spondylolysis
NCT05505981
Recruiting
Spondylolysis, a stress fracture in the pars interarticularis of a lumbar vertebra, is the most common identifiable cause of low back pain (LBP) in adolescent athletes, occurring in 14-30% of athletes who experience LBP. Spondylolysis can cause significant pain and disability and months of exclusion from sports or an active lifestyle. Standard care of spondylolysis in adolescent athletes is primarily based on expert opinion, with dramatic variations in clinical practice, including restrictive br... Read More
Gender:
ALL
Ages:
Between 10 years and 19 years
Trial Updated:
08/23/2024
Locations: Children's Hospital of Colorado, Denver, Colorado +1 locations
Conditions: Lumbar Spondylosis
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Benefits of Endoscopic Bariatric Procedures
NCT05514288
Recruiting
This 12-months long pilot study will include patients undergoing an endoscopic procedure (endoscopic sleeve gastroplasty \[ESG\] or transoral outlet reduction \[TORe\]) as clinically indicated, and subsequent follow up clinic visits for up to one year.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/23/2024
Locations: Liliana Bancila, Los Angeles, California
Conditions: Obesity
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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study
NCT05548283
Recruiting
The purpose of this study is to look at pulmonary exacerbations in people with cystic fibrosis (CF) that need to be treated with antibiotics given through a tube inserted into a vein (intravenous or IV). A pulmonary exacerbation is a worsening of respiratory symptoms in people with CF that needs medical intervention. Both doctors and CF patients are trying to understand the best way to treat pulmonary exacerbations. This study is trying to answer the following questions about treating a pulmonar... Read More
Gender:
ALL
Ages:
6 years and above
Trial Updated:
08/23/2024
Locations: The Children's Hospital Alabama, University of Alabama at Birmingham, Birmingham, Alabama +59 locations
Conditions: Cystic Fibrosis, Cystic Fibrosis Pulmonary Exacerbation
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Neoadjuvant TIL- and Response-Adapted Chemoimmunotherapy for TNBC
NCT05645380
Recruiting
This study will assess if the presence of immune system cells in and around the tumor impacts tumor shrinkage in patients receiving neoadjuvant chemoimmunotherapy for triple-negative breast cancer.
Gender:
FEMALE
Ages:
Between 18 years and 120 years
Trial Updated:
08/23/2024
Locations: The University of Kansas Cancer Center - Clinical Research Center, Fairway, Kansas +6 locations
Conditions: Triple Negative Breast Cancer, Breast Cancer
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Identification of Treatment Concentrations of Defactinib or VS-6766 for the Treatment of Patients With Glioblastoma
NCT05798507
Recruiting
This early phase I trial tests brain concentration level and safety of defactinib or VS-6766 for the treatment of patients with glioblastoma. Recently, two new drugs that seem to work together have been shown to have promising treatment effects in tissue culture and animal models of glioblastoma. Each inhibits a different glioblastoma growth pathway and when used together may create a larger effect on tumor growth than either alone. Growth pathway describes a series of chemical reactions in whic... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
08/23/2024
Locations: Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia
Conditions: Glioblastoma, Recurrent Glioblastoma
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A Study of Bi-Ligand-Drug Conjugate CBP-1019 in Patients With Advanced Solid Tumors
NCT05830097
Recruiting
The primary objective of this phase I study is to evaluate the safety and potential efficacy and to determine the recommended phase 2 dose (RP2D) of CBP-1019, a bi-specific ligand conjugated drugs in patients with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/23/2024
Locations: TOI Clinical Research LLC, Cerritos, California +4 locations
Conditions: Cancer, Breast, Cancer, Lung, Cancer of Pancreas, Cancer of Esophagus, Cancer Colorectal
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Post Market Registry Study of the Philips QuickClear Mechanical Thrombectomy System
NCT05928221
Recruiting
A post-market study of the QuickClear Mechanical Thrombectomy system used for the removal of acute Deep Vein Thrombosis (DVT) from the deep veins of legs in the setting of an office interventional suite.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
08/23/2024
Locations: Vascular Care Connecticut, Darien, Connecticut +5 locations
Conditions: Acute Deep Venous Thrombosis of Ileofemoral Vein
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Multi-modal Imaging of Myofascial Pain
NCT06036524
Recruiting
The goal of this study is to develop new imaging biomarkers for quantitative assessments of myofascial pain.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/23/2024
Locations: Washington University, Saint Louis, Missouri
Conditions: Myofascial Pain
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Treating Amblyopia With CureSight
NCT06165705
Recruiting
Patients with visual acuity and ocular characteristics outside the Novasight FDA multi-center study are to perform the same Curesight procedures- including M\&S EVA or eETDRS patched acuity, stereo and then utilize the Curesight device 1.5 hours per day, 6 days per week over 3-6 months to determine treatment efficacy. An Eye-Tracking-Based Dichoptic Home Treatment for Amblyopia: A Multicenter Randomized Clinical Trial T. Wygnanski-Jaffe, B. J. Kushner, A. Moshkovitz, M. Belkin, O. Yehezkel and... Read More
Gender:
ALL
Ages:
Between 2 years and 20 years
Trial Updated:
08/23/2024
Locations: Alaska Blind Child Discovery, Anchorage, Alaska
Conditions: Amblyopia
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Safety and Efficacy of CS1 CAR-T (WS-CART-CS1) in Subjects With Multiple Myeloma
NCT06185751
Recruiting
Despite recent therapeutic advances, multiple myeloma (MM) remains an incurable disease. Although survival has improved, there are nevertheless diminishing durations of response to each subsequent line of therapy. This highlights the need for further therapeutic innovation. BCMA-targeting CAR-T cells show impressive response rates; however, their median duration of response is disappointing. The investigators propose that CS1(SLAMF7)-targeting CAR-T cells will fill a gap in the MM armamentarium.... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/23/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Multiple Myeloma
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