Evaluating the Efficacy of PECS II Block Versus Axillary Ring Block in Rotator Cuff Repair Patients
Recruiting
Our current standard of care is to perform an interscalene peripheral nerve block for patients receiving rotator cuff repair surgery as it is an effective opioid-free alternative for post-operative pain control. However, many of these repairs require a supplemental incision for an open biceps tenodesis, which is not covered by the interscalene block. The intercostobrachial nerve covers this incision and is targeted by an axillary ring block or a single shot nerve block in the fascial plane betwe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: Healthcare Center 3 - Keck Hospital of USC, Los Angeles, California
Conditions: Shoulder Pain
Augmenting Ankle Plantarflexor Function in Cerebral Palsy
Recruiting
The first specific aim is to quantify improvement in ankle muscle function and functional mobility following targeted ankle resistance gait training in ambulatory children with cerebral palsy (CP). The primary hypothesis for the first aim is that targeted ankle resistance training will produce larger improvements in lower-extremity motor control, gait mechanics, and clinical measures of mobility assessed four- and twelve-weeks post intervention compared to standard physical therapy and standard... Read More
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
02/27/2024
Locations: Gillette Children's Specialty Healthcare, Minneapolis, Minnesota
Conditions: Cerebral Palsy
Continuous Glucose Monitoring in Dialysis Patients to Overcome Dysglycemia Trial
Recruiting
This randomized controlled trial will investigate whether use of continuous glucose monitoring (CGM) vs. usual care with self-monitored blood glucose 1) enhances glycemic control, 2) reduces hypoglycemia risk, and 3) improves quality of life, diabetes distress, and fear of hypoglycemia in hemodialysis patients with diabetes mellitus.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
02/27/2024
Locations: University of California, Irvine, Orange, California
Conditions: Hemodialysis, Diabete Mellitus, Continuous Glucose Monitoring
Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease
Recruiting
The overall aim of the study is to determine the clinical efficacy and mechanisms of action of anti-IL-4a (dupilumab) as treatment for patients with Aspirin-Exacerbated Respiratory Disease (AERD).
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/27/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Nasal Polyps, Asthma, Aspirin-Induced, Aspirin-Exacerbated Respiratory Disease, Aspirin-Sensitive Asthma With Nasal Polyps
Dissemination and Implementation of Improving Pediatric Obesity Practice Using Prompts
Recruiting
The purpose of this study is to evaluate the dissemination and implementation of electronic health record-based clinical decision support tools for the management of pediatric overweight and obesity in primary care.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
02/27/2024
Locations: Eskenazi Health, Indianapolis, Indiana +2 locations
Conditions: Obesity, Childhood
Effectiveness of Relationship Education for Reducing HIV Incidence Among SGM
Recruiting
The purpose of this study is to upgrade an existing relationship education and HIV prevention program. This program is designed for gay, bisexual, queer, and transgender and non-binary people who partner with cisgender men. This means the program is designed for gay, bisexual and queer men, including both cisgender and transgender men. It is also designed for transgender and non-binary people who partner with cisgender men, including both transfeminine and transmasculine people. The investigator... Read More
Gender:
ALL
Ages:
Between 16 years and 34 years
Trial Updated:
02/27/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Hiv, Chlamydia, Gonorrhea
Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0
Recruiting
The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main questions it aims to answer whether residents with dementia in nursing homes randomized to use a multicomponent intervention to optimize suspected infection management ( versus usual care) use less antibiotics and fewer burdensome interventions.
Gender:
ALL
Ages:
Between 60 years and 106 years
Trial Updated:
02/27/2024
Locations: Hebrew SeniorLife, Boston, Massachusetts
Conditions: Dementia, Alzheimer Disease, Infections
Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace
Recruiting
The Investigators are studying the effect of an ACL reconstruction on return to play by capturing outcome measures and biomechanics information.
Gender:
ALL
Ages:
Between 14 years and 26 years
Trial Updated:
02/27/2024
Locations: Marshall University, Huntington, West Virginia
Conditions: Anterior Cruciate Ligament Rupture
KEEP Connecting Kin
Recruiting
The current study provides a unique opportunity to conduct a summative evaluation of the KEEP Connecting Kin (KEEP-CK) program by leveraging extant relationships with Oregon's Child Welfare System (CWS), Self-Sufficiency Program (SSP), and our community partners to address the needs of informal kinship families and the youth in their care. Specifically, a randomized "services-as-usual" (SAU) waitlist control design plus qualitative methods will be used to evaluate the immediate (post-interventio... Read More
Gender:
ALL
Ages:
Between 4 years and 18 years
Trial Updated:
02/27/2024
Locations: Oregon Center Learning Center, Eugene, Oregon
Conditions: Internalizing Behavior, Externalizing Behavior, Child Permanency, Parenting, Parent Stress, Service Utilization
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: University of Alabama, Birmingham, Alabama +182 locations
Conditions: Huntington's Disease
Tension Versus no Tension With Foley Bulb Induction
Recruiting
To compare the application of tension versus no tension in Foley transcervical catheters for pre-induction cervical ripening.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Kapiolani Medical Center for Women and Children, Honolulu, Hawaii
Conditions: Induction of Labor Affected Fetus / Newborn
Trial to Evaluate Safety and Tolerability of GP-2250 in Combination With Gemcitabine
Recruiting
This is a phase 1 first in human, dose escalation trial of GP-2250 administered in combination with gemcitabine in subjects with advanced pancreatic cancer previously treated with 5-fluorouracil-based chemotherapy. Prior radiosensitization with gemcitabine, the use of 5-fluorouracil, FOLFIRINOX or Nab-paclitaxel/gemcitabine in the neoadjuvant setting, and prior pancreaticoduodenectomy (Whipple procedure) is allowed. If prior treatment with gemcitabine was at therapeutic doses, a minimum of 3 mo... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Hoag Family Cancer Institute, Newport Beach, California +4 locations
Conditions: Pancreatic Cancer, Adult