Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral Trial
Recruiting
This study will unpack the behavioral intervention for migraine and determine the optimum combinations. In addition, the study will test preference and self-selection effects during the trial.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/26/2024
Locations: Stanford University, Stanford, California
Conditions: Migraine, Headache, Chronic Migraine, Headache Disorders
Genesis Electrical Impedance Tomography (EIT): A Preliminary Study
Recruiting
The purpose of this study is to evaluate the Genesis Electrical Impedance Tomography (EIT) imaging system for use in pediatric respiratory disease populations including neuromuscular and bronchopulmonary dysplasia, as well as in age and height matched controls. The EIT does not use radiation, and is read through electrodes.
Gender:
ALL
Ages:
Between 14 days and 40 years
Trial Updated:
01/25/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Premature Infant, Chronic Respiratory Disease, Neuromuscular Diseases, Healthy, Bronchopulmonary Dysplasia, Pulmonary Vein Stenoses
Pulmonary Health in Children With Down Syndrome
Recruiting
The goal of the study is to learn more about tests that can assess lung health in children with Down syndrome.
Gender:
ALL
Ages:
Between 3 years and 18 years
Trial Updated:
01/25/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Down Syndrome, Dysphagia, Oropharyngeal
Mind Body Program Vascular
Recruiting
The purpose of the current study is to conduct a proof-of-concept test regarding the delivery of a Mind Body Program for vascular disease, focusing on support for depression, stress, and adherence, as part of patients' chronic disease management for peripheral artery disease (PAD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/25/2024
Locations: Yale New Haven Health Hospital, New Haven, Connecticut
Conditions: Peripheral Arterial Disease, Peripheral Vascular Diseases
Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts
Recruiting
The DART-HA study is a single-center, open label, trial intended to evaluate the clinical efficacy of standard treatment options for congestive heart failure (observation, diuretic or afterload reduction therapy) in patients without new symptoms who have developed abnormalities of the HeartLogic heart failure diagnostic feature.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
01/25/2024
Locations: Heart Center Research, LLC, Huntsville, Alabama
Conditions: Heart Failure, Congestive
Central and Peripheral Effects of Cognitive Behavioral Therapy on Brain-Gut Axis Signaling in Gastroparetic Patients
Recruiting
This is a single-center pilot study to be conducted at Massachusetts General Hospital. The purpose of this study is to examine the non-pharmacological impact of Cognitive Behavioral Therapy (CBT) on gastroparesis symptoms and other clinical co-comorbidities such as pain, depression, anxiety, and catastrophizing. CBT trial patients will undergo careful phenotyping pre- and post- intervention with brain MRI, autonomic function test (AFT), gastric emptying scintigraphy (GES), and nutrient drink tes... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/24/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Gastroparesis
Biomarker Monitoring of Prostate Cancer Patients With RSI MRI (ProsRSI)
Recruiting
Adult male patients with high-risk, localized prostate cancer and planning to undergo radiation therapy (RT) with androgen deprivation therapy (ADT) will undergo an advanced Magnetic Resonance Imaging (MRI) examination called Restriction Spectrum Imaging (RSI-MRI) to evaluate whether RSI-MRI can predict treatment response.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: UCSD Moores Cancer Center, La Jolla, California
Conditions: Prostate Cancer
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Pinnacle Research Group, Anniston, Alabama +493 locations
Conditions: NASH - Nonalcoholic Steatohepatitis
A Study to Investigate Fadraciclib (CYC065), in Subjects With Advanced Solid Tumors and Lymphoma
Recruiting
This is a 2-part, phase 1/2, open-label, multicenter study designed to evaluate the safety, tolerability, PK, pharmacodynamics, PGx, and efficacy of fadraciclib administered orally BID. This study consists of Phase 1 and Phase 2 components in subjects with advanced solid tumors and lymphoma who have progressed despite having standard therapy or for which no standard therapy exists.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: City of Hope, Duarte, California +3 locations
Conditions: Solid Tumor, Adult, Lymphoma
Robotic Mechanical Coring for the Treatment of Moderate to Severe Facial Wrinkles
Recruiting
This study is a prospective, up to 4 center study of the safety and efficacy of mechanical coring with skin closure of cored holes, intended for the improvement in the appearance of wrinkles of the cheeks in up to 70 subjects after two treatments.
Gender:
ALL
Ages:
Between 22 years and 75 years
Trial Updated:
01/24/2024
Locations: DeNova Research, Chicago, Illinois +1 locations
Conditions: Wrinkle
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
Recruiting
VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, transmagnetic stimulation (TMS), and MRI measures in the acute stroke time window.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: University of Alabama, Birmingham, Alabama +32 locations
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic
Home-based Transcranial Direct Current Stimulation (tDCS) for Behavioral Symptoms in Alzheimer's Disease and Related Dementias (ADRD)
Recruiting
The purpose of this study is to assess acceptability, and safety of providing tDCS to ADRD patients with behavioral symptoms and to assess the efficacy of tDCS for ADRD-related symptoms, mainly behavioral symptoms.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
01/24/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Alzheimer Disease