Treatment Recommendations for Gastrointestinal Cancers Via Large Language Models
NCT06002425
Recruiting
This study will evaluate the utility of ChatGPT in recommending treatment plans for patients with gastrointestinal cancers, using both retrospective and prospective data.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/06/2023
Locations: City of Hope, Duarte, California +6 locations
Conditions: Gastrointestinal Neoplasm Malignant
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Study of 3D Scanning for Adolescent Scoliosis
NCT06035952
Recruiting
The investigators aim to validate three-dimensional topographical scanning technology as a tool for evaluation of scoliosis. Through the incorporation of 3D topographical technology in the measurement of deformity, the investigators hope to validate a novel approach to quantify deformity progression and provide an accessible alternative to traditional radiographic workup.
Gender:
ALL
Ages:
Between 10 years and 18 years
Trial Updated:
09/06/2023
Locations: Stanford University School of Medicine, Palo Alto, California +1 locations
Conditions: Scoliosis
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Opioid Package Prototype (OPP)
NCT04598074
Recruiting
The overall objective of this clinical trial is to identify the impact of selected package features, known as the Opioid Package Prototype (OPP), on the safe and effective use of opioids. Our specific aims are: (Aim 1) to evaluate the effectiveness of OPP on prescribing, dispensing, and patient use of oxycodone among orthopaedic surgery patients receiving post-operative outpatient oxycodone for post-surgical pain management, and (Aim 2) to determine the feasibility of OPP for orthopaedic surgery... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/05/2023
Locations: UConn Health, Farmington, Connecticut
Conditions: Opioid Use, Opioid Prescribing, Dispensing, and Patient Use
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Engaging Men in Weight Loss With a Game-based mHealth and Neurotraining Program
NCT05408494
Recruiting
Men in the United States have an exceptionally high prevalence of overweight and obesity, i.e., 71.3%, and 42% of men are currently attempting weight loss. However, men are dramatically underrepresented in weight loss programs. Attempts to modestly adapt standard weight loss programs have seen only minimal success. Mobile applications (mHealth apps) have attractive features, but have low male enrollment and poor efficacy as conventionally delivered. A gamified mHealth program offers the possibil... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
09/05/2023
Locations: Drexel University, Philadelphia, Pennsylvania
Conditions: Obesity, Weight Loss
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Symphony IL-6 Study in Patients at Risk of Severe Sepsis
NCT05665153
Recruiting
Symphony IL-6 is a device that quantitates human IL-6 by fluorescence enzyme immunoassay (FEIA) from whole-blood specimens. Use of Symphony IL- 6 removes the need for plasma separation before testing. Symphony IL-6 comprises two components, the Symphony Fluorescence Immunoanalyzer and the Symphony IL-6 Cartridge. Whole blood is added to the cartridge and then up to six cartridges can be inserted into the immunoanalyzer. After 20 minutes a readout and printout are given with a quantitative IL-6 c... Read More
Gender:
ALL
Ages:
22 years and above
Trial Updated:
09/05/2023
Locations: University of Michigan Medical Center, Ann Arbor, Michigan
Conditions: Severe Sepsis
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Sleep in SNOO Smart Sleeper Bassinet in Preterm Infants
NCT05711927
Recruiting
The goal of this clinical trial is to compare sleeping in a SNOO Smart Sleeper bassinet (SNOO) with sleeping in traditional bassinet conditions in premature infants. The main questions it aims to answer are: 1. Do preterm infants who sleep in the SNOO have more quiet sleep? 2. Do preterm infants who sleep in the SNOO have improved vital signs? * Participants will spend two separate three-hour periods sleeping in either a SNOO (which plays white noise and rocks from side-to-side) or in a SNO... Read More
Gender:
ALL
Ages:
Between 1 week and 12 weeks
Trial Updated:
09/05/2023
Locations: Morgan Stanley Children's Hospital Neonatal Intensive Care Unit, NewYork Presbyterian, New York, New York
Conditions: Prematurity, Very Preterm Maturity of Infant
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A Study of ASKG915 in Patients With Selected Advanced Solid Tumors.
NCT05867420
Recruiting
The study is a Phase 1dose escalation study to evaluate the safety, tolerability, and pharmacokinetics of ASKG915 as a single agent in patients with selected advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/05/2023
Locations: Columbia University Irving Medical Center, New York, New York +1 locations
Conditions: Advanced Solid Tumors
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Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.
NCT06030297
Recruiting
The R61 will perform a four-part double-blind randomized crossover study transitioning from a pretreatment baseline phase, to randomized treatment with either lidocaine or an identical placebo patch, washout, and alternate arm. DLss measures will be obtained before and after each phase. Twice daily report of pain using a visual analogue scale will track severity of ongoing spontaneous pain in participants. The hybrid biomarker will distinguish between placebo and active treatment arms, will sign... Read More
Gender:
ALL
Ages:
Between 18 years and 69 years
Trial Updated:
09/05/2023
Locations: Stanford University, Palo Alto, California +1 locations
Conditions: Peripheral Neuropathy
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Immune Response to C.Difficile Infection
NCT02797288
Recruiting
The protocol aims to address the basic mechanisms of Clostridium difficile pathogenesis by identifying how a Th 17 response impacts severity of C. difficile infection and how Type II immunity protects the gut from Clostridium difficile toxin-induced damage. This could lead to new and effective approaches to the treatment or prevention of Clostridium difficile colitis that act downstream of fecal microbiota transplants (FMT) or next generation probiotics. Successful fecal microbial transplantatio... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/03/2023
Locations: University of Virginia Health System, Charlottesville, Virginia
Conditions: Clostridium Difficile
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A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis
NCT05181137
Recruiting
This is a randomized, double-blind, placebo-controlled, multicenter Phase 3 study that will enroll approximately 368 subjects aged 18 to 75 years old with Moderately to Severely Active Ulcerative Colitis.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
09/01/2023
Locations: Digestive Health Specialists, Dothan, Alabama +112 locations
Conditions: Ulcerative Colitis
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Semaglutide Treatment in the Real-world for Fibrosis Due to NAFLD in Obesity and T2DM
NCT06005012
Recruiting
Conduct a community intervention study that will 1) validate a screening approach to identify patients at risk for advanced NAFLD in the obese or T2DM population, and 2) test whether semaglutide treatment is effective for the management of significant fibrosis due to NAFLD in high-risk patients.
Gender:
ALL
Ages:
Between 40 years and 79 years
Trial Updated:
09/01/2023
Locations: University of California, San Diego, La Jolla, California
Conditions: Fibrosis, Liver, Type 2 Diabetes Mellitus in Obese, Non-Alcoholic Fatty Liver Disease
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Adherence to Different Exercise Interventions
NCT06024577
Recruiting
Only 50% of sedentary adults that start an exercise training program adhere to the program after 6 months. Exercise variety may improve adherence. The goal of this study is to examine different exercise interventions that include a variety of exercise on adherence.
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
09/01/2023
Locations: California Polytechnic State University, San Luis Obispo, California
Conditions: Exercise Adherence
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