A Research Study on How a Dose of NNC0662-0419 Works in Japanese, Chinese and Non-Asian Participants Living With Overweight or Obesity
NCT07101783
Recruiting
The study is testing the new medicine NNC0662-0419 in people living with overweight or obesity. The purpose of the study is to look into the amount of the new medicine NNC0662-0419 in participants blood after one dose. And also look into how safe and how well the study medicine is tolerated in people living with overweight or obesity. NNC0662-0419 is a new medicine which cannot be prescribed by doctors. NNC0662-0419 is currently being tested in humans and the dose participants will receive has b... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
08/06/2025
Locations: Altasciences Clinical LA, Inc., Cypress, California
Conditions: Overweight, Obesity
Register for Updates
Driver Education Research Study
NCT06413927
Recruiting
This study will test the effectiveness of different types of driver training interventions for reducing young new driver crash risk early after licensure.
Gender:
ALL
Ages:
Between 16 years and 17 years
Trial Updated:
08/06/2025
Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Conditions: Risk Reduction Behavior, Injuries, Accident, Traffic, Development, Adolescent
Register for Updates
Inflammatory Bowel Disease (IBD) Research Registry
NCT04243525
Recruiting
Patients seen at the Center for Inflammatory Bowel Disease will be asked to provide their written informed consent (authorization) to allow their identifiable medical record information related to their Inflammatory Bowel Disease to be placed in Center's Research Registry for the purpose of facilitating retrospective research studies directed at Inflammatory Bowel Disease, and the identification and recruitment of potential, eligible subjects for participation in future research studies involvin... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/06/2025
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis)
Register for Updates
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
NCT03937817
Recruiting
Background: Blood disorders like sickle cell disease and malaria affect many people around the world. Researchers want to learn more about blood disorders. To do this, they need to collect biological samples from people with blood disorders. They also need to collect samples from healthy people. Objective: To collect samples to use for research on blood disorders. Eligibility: People ages 18-70 who have blood disorders. Healthy volunteers without blood disorders are also needed. Design: P... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
08/05/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Sickle Cell Disease, Malaria, Human Physiology, Alpha and Beta Thalassemia
Register for Updates
Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility
NCT01354002
Recruiting
The aims of this protocol are: to collect and store diseased and normal tissue and body fluid samples from new and returning patients at St. Jude Children's Research Hospital (SJCRH), affiliated sites and collaborating institutions; to collect and store samples from relatives of SJCRH patients; to collect and store retrospective and prospective pertinent corresponding clinical and laboratory data on disease characterization, treatment, and outcome; and to serve as a source of human biological sa... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/05/2025
Locations: St. Jude Clinic at Huntsville Hospital for Women & Children, Huntsville, Alabama +13 locations
Conditions: Normal and Diseased Tissue and Body Fluids Samples
Register for Updates
Neurosciences Research Repository
NCT00857922
Recruiting
In order to expand neuroscience research and move laboratory advances to patients, there is a need to integrate reliable clinical data with biologic information from patient tissue specimens. The Neuroscience Research Repository (NRR) seeks to meet this need. The NRR is a prospective database and sample bank created to collect information and samples for current and future neuroscience research. The objective of this NRR is to develop a data and sample repository for study of neurological condit... Read More
Gender:
ALL
Ages:
0 years and above
Trial Updated:
08/05/2025
Locations: Memorial Hermann Hospital, Houston, Texas
Conditions: Neurological Conditions
Register for Updates
United States Hypophosphatasia Molecular Research Center
NCT05062629
Recruiting
This study is being done to determine if cryptic alterations exist within or near to the ALPL gene in patients with a clinical diagnosis of hypophosphatasia, but without identifiable alteration on commercial testing. Additionally, the study aims to characterize functional effects of certain variants of uncertain significance in patients with clinical diagnosis of hypophosphatasia.
Gender:
ALL
Ages:
All
Trial Updated:
08/04/2025
Locations: Children's Mercy Hospital, Kansas City, Missouri
Conditions: Hypophosphatasia
Register for Updates
Near-InfraRed Spectroscopy of Auricular Stimulation
NCT06825364
Recruiting
This is a single-visit non-invasive study of healthy volunteer subjects. Brain activity will be measured with infra-red light sensors attached to a cap worn on the head, while both ears are gently stimulated with plastic filaments.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/04/2025
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Healthy Male and Female Subjects, Healthy Volunteer Study
Register for Updates
Prospective Research Rare Kidney Stones (ProRKS)
NCT02780297
Recruiting
The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of ren... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/02/2025
Locations: University of Alabama @ Birmingham, Birmingham, Alabama +10 locations
Conditions: Hyperoxaluria, Cystinuria, Dent Disease, Lowe Syndrome, Adenine Phosphoribosyltransferase Deficiency
Register for Updates
REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors)
NCT05973773
Recruiting
The purpose of this study is to evaluate the safety and efficacy of zipalertinib in combination with standard first-line platinum-based chemotherapy compared to chemotherapy alone, in patients with locally advanced or metastatic NSCLC with EGFR ex20ins mutations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/31/2025
Locations: Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada +130 locations
Conditions: Advanced or Metastatic NSCLS With Exon 20 Insertion Mutation
Register for Updates
Small Cell Lung Cancer Community Engagement to Eliminate Research Discepancies
NCT06486428
Recruiting
This study will evaluate if a direct-to-patient, de-centralized, remote approach will improve clinical research outreach and engagement for patients with SCLC, in the context of a bio-specimen collection study. The study will also assess self-reported preferences and needs of patients with SCLC, regarding choosing and accessing novel therapies in research or standard clinical care settings and supportive gaps in this area, through an initial and 3 month follow up survey.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/30/2025
Locations: Https://Alcmi.Org/Clinical-Trials/Current-Studies/Succeed-Study.Html, Multiple Locations, Alabama +51 locations
Conditions: Small-cell Lung Cancer
Register for Updates
Long-Term Follow-Up of Recipient of Gene Transfer Research
NCT01492036
Recruiting
The goal of this clinical research study is to collect information about the long-term safety of gene transfer therapy. This study is also designed to create a database of medical information about patients who have received gene transfer therapy, in order for researchers to track and review the long-term safety and any effects (good or bad) of gene transfer therapy.
Gender:
ALL
Ages:
All
Trial Updated:
07/30/2025
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Retroviridae Infections, Cancer
Register for Updates