Lung Ultrasound - Prospective Study
Recruiting
The goal of this clinical trial is to determine whether lung ultrasound can predict extubation success in neonates with respiratory distress. Participants will undergo a lung ultrasound pre- and post-extubation.
Gender:
ALL
Ages:
6 months and below
Trial Updated:
05/13/2025
Locations: University of Minnesota, Minneapolis, Minnesota +1 locations
Conditions: Respiratory Distress of Newborn
The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia
Recruiting
In this research study the investigators will use sleep headbands to measure brain rhythms and to improve their coordination across brain regions. The headbands will be worn at home for multiple nights. On some nights the headbands will play soft sounds at specific times during sleep. The investigators are interested in learning whether this timed auditory stimulation may be a strategy to improve the coordination of sleep rhythms across brain regions, improve network communication, and as a resu... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
05/13/2025
Locations: Massachusetts General Hospital, Charlestown, Massachusetts
Conditions: Schizophrenia
Mindfulness Training and Respiration Biosignal Feedback - Study 1
Recruiting
The goal of this research is to develop a new breathing feature on the meditation app, Equa, to help young adults who are distressed, understand their physiological responses and mindfulness skill development during meditation. Our main aims are to build an algorithm that can use physiologic signals to: * Give feedback about how participant physiology is changing during guided lessons on the meditation app, Equa * Measure how much participant mindfulness skills are improving Participants will... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
05/13/2025
Locations: GATF Building, 4615 Forbes Avenue, Pittsburgh, Pennsylvania
Conditions: Psychological Distress, Develop a Respiration Biosignal Feedback Algorithm, Utilize Respiration Algorithm to Predict Mindfulness Skills
Comparing Mirror Therapy Rehabilitation Device to Conventional Mirror Therapy
Recruiting
This is a randomized controlled trial which will compare conventional mirror therapy with mirror therapy using the Miraπ device which physically moves a patient's affected limb. This study will use two parallel groups: (1) receiving conventional mirror therapy as a part of the standard of care as conducted by the participant's clinical care team and (2) receiving mirror therapy with the Miraπ device as conducted by study personnel with the oversight of the participant's clinical care team.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2025
Locations: Rehabilitation and Wellness Center at the Milford Campus of Bridgeport Hospital, Milford, Connecticut
Conditions: Stroke, Pain, Impaired Motor Function
A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM
Recruiting
An observational study to assess real-world patient characteristics and clinical course of disease in participants with PKP2-ACM.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/13/2025
Locations: Leland Stanford Junior University, Redwood City, California +5 locations
Conditions: Arrhythmogenic Cardiomyopathy, PKP2-ACM, PKP2-ARVC
Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease
Recruiting
This study is being done to find out how often endometrial cancer recurs after the standard treatment as well as how often the standard treatment results in a lymphedema.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/13/2025
Locations: Hartford Healthcare Cancer Institute @ Hartford Hospital, Hartford, Connecticut +18 locations
Conditions: Endometrial Cancer, Endometrioid Adenocarcinoma, Endometrial Cancer Stage I
Parent Intervention for Psychiatrically-Hospitalized Youth
Recruiting
The purpose of the present study is to conduct a pilot randomized clinical trial (RCT) of a parent coaching intervention for parents of youth hospitalized for suicidal ideation, suicide attempt(s), or non-suicidal self-injury. Parents will receive either the parent coaching intervention (which includes safety planning and behavioral parenting skills training with a clinician and assistance with linkage to follow-up care by a case manager) or treatment as usual (TAU) for the inpatient unit. The l... Read More
Gender:
ALL
Ages:
Between 12 years and 85 years
Trial Updated:
05/13/2025
Locations: Michele Berk, Stanford, California
Conditions: Adolescent - Emotional Problem, Suicide and Self-harm, Parenting
Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma
Recruiting
Proposed treatment of subjects with newly diagnosed glioblastoma with novel personalized drug regimens identified to be effective in vitro using cancer stem cells derived from their individual tumors, alongside standard of care radiation and TMZ.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2025
Locations: Swedish Medical Center, Seattle, Washington
Conditions: Newly Diagnosed Glioblastoma
Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)
Recruiting
This is a research study to test the safety and effectiveness of using the drug alpelisib together with chemotherapy (nab-paclitaxel) and a drug called L-NMMA in patients with HER2 negative metastatic or locally advanced metaplastic breast cancer, who have not responded to previous treatments. Participants in this study in addition to the standard care chemotherapy will also receive the drug alpelisib and L-NMMA. The therapies will be administered every 3 weeks (1 cycle) until disease progressi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2025
Locations: National Institute of Health Clinical Center, Bethesda, Maryland +2 locations
Conditions: HER2-negative Breast Cancer, Metastatic Breast Cancer, Metaplastic Breast Carcinoma, TNBC - Triple-Negative Breast Cancer
A Study of GDX012 in Adults With Relapsed or Refractory Acute Myeloid Leukemia
Recruiting
GDX012 is a novel cell therapy developed for the treatment of certain types of cancer, including Acute Myeloid Leukemia (AML). The main aims of the study are to learn how safe GDX012 is, how treatment with GDX012 is tolerated and to determine the best dose of GDX012.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2025
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama +13 locations
Conditions: Leukemia
Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma
Recruiting
Multiple myeloma (MM) is a cancer of the blood's plasma cells. The cancer is typically found in the bones and bone marrow (the spongy tissue inside of the bones) and can cause bone pain, fractures, infections, weaker bones, and kidney failure. Treatments are available, but MM can come back (relapsed) or may not get better (refractory) with treatment. This is a study to determine change in disease symptoms of etentamig compared to standard available therapies in adult participants with relapsed/r... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2025
Locations: University of Alabama at Birmingham - Main /ID# 261434, Birmingham, Alabama +141 locations
Conditions: Multiple Myeloma
Early Chest Tube Removal After Surgery for Primary Spontaneous Pneumothorax: A Randomized Controlled Trial
Recruiting
Video-assisted thoracoscopic surgery (VATS) with blebectomy/wedge resection plus pleurodesis is the standard of care for recurrent primary spontaneous pneumothorax (PSP) or, in certain instances, after the first episode. The chest tube from surgery is typically kept to suction until post-operative day (POD) 2 to allow for scarring of the lung to the chest to prevent recurrence. However, the scarring process takes place over a period of weeks and is there no data to support POD#2 as the best time... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2025
Locations: Swedish Cancer Institute, Seattle, Washington
Conditions: Primary Spontaneous Pneumothorax