HVLAT, Electric DN, Exercise Vs. Mobilization, STM, Exercise, TENS for Tension Type Headaches
NCT04609709
Recruiting
The purpose of this research is to compare two different approaches for treating patients with tension-type headaches: thrust Manipulation, electric dry Needling and exercise Vs. non-thrust mobilization, soft-tissue mobilization, exercise and TENS. Physical therapists commonly use all of these techniques to treat tension-type headaches. This study is attempting to find out if one treatment strategy is more effective than the other.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/14/2025
Locations: Maller and Swoverland Orthopedic PT, Fort Wayne, Indiana
Conditions: Tension-Type Headache
Register for Updates
Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents
NCT05268042
Recruiting
This will be a 6-month randomized clinical trial with two arms: moderately carbohydrate-restricted diet and a fat-restricted control diet. This 6-month study will have 2 phases: a 12-week controlled feeding phase and a 12-week "free living" phase. During the controlled feeding phase, all food will be provided to the families of the participants for the entirety of the 12 weeks. Participants (n=80) will have been diagnosed with NAFLD based on the presence of current evidence of active disease, wh... Read More
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
05/14/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Non-Alcoholic Fatty Liver Disease, Obesity
Register for Updates
The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head
NCT05706909
Recruiting
The purpose of this study is to assess the clinical and x-ray results of patients who are treated with core decompression of the hip and the injection of a bone marrow concentrate and the use of the Bone Graft Substitute Genex®.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/14/2025
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Avascular Necrosis, Osteonecrosis
Register for Updates
Habit Awareness Device for Treatment of Onychophagia
NCT06111729
Recruiting
This clinical trial wants to find out if using a special bracelet that vibrates gently whenever someone with a nail-biting problem bites their nails can help them stop. The investigators are looking at adults who bite their nails a lot. If this bracelet works, it could make nail-biters bite their nails less and have a better life. The main question the investigators are trying to answer is: "Does the gentle vibration from the bracelet make people bite their nails less?" The investigators will... Read More
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
05/14/2025
Locations: Weill Cornell Department of Dermatology, New York, New York
Conditions: Nail Biting
Register for Updates
Cemiplimab and Cetuximab Prior Salvage Surgery in Patients With Recurrent Oral Cavity Squamous Cell Carcinoma (OCSCC).
NCT06448026
Recruiting
To learn if giving cemiplimab and cetuximab before salvage surgery can help to control recurrent oral cavity squamous cell carcinoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/14/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Locally Recurrent Oral Cavity Squamous Cell Carcinoma
Register for Updates
Music During Allogeneic Stem Cell Transplant Hospitalization
NCT06679530
Recruiting
The goal of this trial is to develop an Independent Music Listening tool for stem cell transplant patients that have prolonged hospitalizations. The main questions it aims to answer are: \[primary hypothesis or outcome measure 1\]? \[primary hypothesis or outcome measure 2\]? Participants will use a self-guided music listening intervention of 1-hour daily music listening during their inpatient hsopitalization and delivered via web-based platform.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/14/2025
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Hematopoietic Cell Transplantation (HCT)
Register for Updates
Tirzepatide in PWS, HO and GNSO
NCT06901245
Recruiting
This research study is comparing the effectiveness of a weight loss medication called Tirzepatide in young adults with Prader-Willi Syndrome and/or hypothalamic obesity, as compared to young adults with obesity that is unrelated to a genetic syndrome or underlying medical cause. These groups will be given medication for 1 year to see how weight and other health factors are effected by the medication.
Gender:
ALL
Ages:
Between 18 years and 26 years
Trial Updated:
05/14/2025
Locations: Children's Minnesota, Minneapolis, Minnesota +2 locations
Conditions: Prader-Willi Syndrome, Hypothalamic Obesity, Obesity/Therapy
Register for Updates
Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy
NCT03630991
Recruiting
This phase I trial studies the side effects and best dose of edetate calcium disodium or succimer in treating patients with acute myeloid leukemia or myelodysplastic syndrome undergoing chemotherapy. Edetate calcium disodium or succimer may help to lower the level of metals found in the bone marrow and blood and may help to control the disease and/or improve response to chemotherapy.
Gender:
ALL
Ages:
1 year and above
Trial Updated:
05/14/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, High Risk Myelodysplastic Syndrome, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm, Myeloproliferative Neoplasm, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic Syndrome, Secondary Acute Myeloid Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Myelodysplastic/Myeloproliferative Neoplasm, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Secondary Myelodysplastic Syndrome, Very High Risk Myelodysplastic Syndrome
Register for Updates
Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers
NCT04645160
Recruiting
Background: Cholangiocarcinoma (CCA) is an aggressive cancer of the bile ducts. People with CCA have few treatment options and poor survival. Researchers want to see if a new drug can stop or slow CCA growth. Objective: To find the safest and most effective dose of tivozanib to treat CCA and learn its overall response rate. Eligibility: Adults ages 18 and older with CCA not removable with surgery and have been treated with at least one type of chemotherapy. Design: Participants will be sc... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/14/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Cholangiocarcinoma, Bile Duct Neoplasm, Biliary Tract Malignancy
Register for Updates
A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumor
NCT05275426
Recruiting
The purpose of this study is to find out whether LY2880070 combined with the chemotherapy drug gemcitabine is an effective treatment for Ewing sarcoma or Ewing-like sarcoma.
Gender:
ALL
Ages:
All
Trial Updated:
05/14/2025
Locations: Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York
Conditions: Ewing Sarcoma, Ewing-Like Sarcoma
Register for Updates
Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance
NCT05796375
Recruiting
The purpose of this research is to determine whether bladder cancer monitoring can be improved by replacing some cystoscopy procedures with urine testing. Specifically, this study examines whether there are any differences in urinary symptoms, discomfort, number of invasive procedures, anxiety, complications, cancer recurrence or cancer progression when some cystoscopy procedures are replaced with urine testing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/14/2025
Locations: Bay Pines VA Healthcare System, Bay Pines, Florida +6 locations
Conditions: Non-muscle-invasive Bladder Cancer
Register for Updates
Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents
NCT06120491
Recruiting
The intention of the study is to demonstrate superiority of Saruparib (AZD5305) + physician's choice NHA relative to placebo + physician's choice NHA by assessment of radiographic progression-free survival (rPFS) in participants with mCSPC.
Gender:
MALE
Ages:
Between 18 years and 130 years
Trial Updated:
05/14/2025
Locations: Research Site, Chandler, Arizona +408 locations
Conditions: Metastatic Castration-Sensitive Prostate Cancer
Register for Updates