All Clinical Trials

A listing of 23115 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Featured Trial

Healthy Participants Needed (Colonoscopy + Cancer Screening)

Recruiting

Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.

Conditions:

Healthy

Healthy Volunteers

Healthy Subjects

Healthy Volunteer

Healthy Participants

Learn More

Featured Trial

Buy Retatrutide Online Through Celia

Recruiting

Retatrutide (formerly M25) is an investigational peptide being studied for its potential in supporting weight management and metabolic health. It acts on GLP-1, GIP, and glucagon receptors to influence appetite, energy regulation, and fat metabolism.

Conditions:

Healthy

Learn More

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Semaglutide and Tirzepatide are advanced GLP-1 medications designed to support weight management and metabolic health. They work by targeting GLP-1 receptors in the body, helping regulate appetite, improve blood sugar control, and support sustainable weight loss (up to 22% of body weight).

Get $50 off your first order using promo code: policy-lab-50

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

Learn More

Featured Trial

Birth Control Clinical Research Study

Recruiting

Living with obesity and looking for a birth control option that is right for you? Clinical trials are now enrolling women with a body mass index (BMI) of 30 or more in the area to help study a potential new progestin-only contraceptive patch. Participating in research studies can help advance birth control options. Don’t let financial stress hold you back. All study-related assessments, care, and study patch are available at no cost. You may also be reimbursed for study-related travel.

Conditions:

Obesity

Overweight

Overweight and Obesity

Learn More

Featured Trial

Depression Clinical Trial

Recruiting

Join us in researching a potential investigational treatment for Depression. Reimbursement for study-related expenses may be available to you.

Qualifying participants:
•Are between 18-65
•Have been experiencing a major depressive episode for at least a month

Conditions:

Depression

Major Depressive Disorder

Depressive Disorder

Depressive Symptoms

Depressive Disorder

Learn More

Featured Offer

Ketamine Therapy—At Home, Clinician-Guided (Innerwell)

If you’re exploring options besides a clinical trial, Innerwell provides at-home ketamine therapy with medical oversight and structured support. Ketamine-assisted treatment may help “reset” rigid stress and mood patterns, and some people feel relief within a few sessions. Your care team works with you to tailor treatment and track progress every step of the way. Proven effective for Anxiety, PTSD, Depression, Addiction, and other disease areas.

Conditions:

Anxiety

Anxiety Disorders

Generalized Anxiety Disorder

Depression

Learn More

Orexin s Role in the Neurobiology of Substance Use Disorder

NCT05630781

Recruiting

Study Description: Despite the availability of pharmacotherapy for some substance use disorders, relapse vulnerability is still a significant issue. This suggests medications with alternative mechanisms of action should be explored to address this unmet need. Substantial preclinical research indicates that orexin antagonism blunts the internally and externally triggered motivation to attain abused substances. This research project will translate these preclinical findings into the clinical domain by administering the FDA approved orexin antagonist, suvorexant, to those with a substance use disorder. Suvorexant s ability to blunt neurobiological correlates of substance misuse will be assessed. This will be assessed following acute and repeated drug administration. Baseline individual differences will be considered to determine whether neurobiological variance influences suvorexant s impact in those with nicotine dependence. In an independent arm, the interaction between suvorexant and a dopamine agonist (methylphenidate) on cognitive function will be assessed in non-smoking individuals. Objectives: The objective is to determine the acute and chronic impact of the orexin antagonist, suvorexant, on neurobiological and behavioral factors linked with substance use disorders. Whether such effects are mediated by baseline characteristics will be tested. Given suvorexant is an FDA approved treatment for insomnia, sleep will be evaluated as well in the nicotine dependent arm. Endpoints: In nicotine-dependent individuals, suvorexant s impact on brain function will be assessed several ways by evaluating: 1) resting function, 2) reactivity to drug cues, 3) reactivity to non-drug related cognitive tasks. Sleep and nicotine use will be measured throughout the study period. In those without nicotine-dependence, the impact of suvorexant and the interaction of acute methylphenidate and suvorexant on brain function will be assessed. This arm will provide insight into how suvorexant impacts reward/cognition as well as impacts the pharmacological influence of methylphenidate on those same measures. Study Population:\<TAB\> Nicotine dependence arm:140 subjects; Volunteers who are between the ages of 18-60 and are daily smokers/vapers. Control arm: 80 subjects; Volunteers who are between the ages of 18-60 and are non-smokers/vapers This study will be conducted at the NIDA-IRP, Biomedical Research Center, in Baltimore, MD. Description of Study Intervention: Nicotine dependence arm: Suvorexant at 10 mg single dose, and Suvorexant at 10 mg daily for approximately 7 days. Control arm: 1. Tolerability visit with one MRI scan post-20mg methylphenidate, 4 acute drug administration (6-14 days in randomized order: 1. Placebo + placebo; 2. 20mg suvorexant + Placebo; 3. Placebo + 40mg methylphenidate; 4. 20 mg suvorexant + 40mg methylphenidate max) Study Duration: 5 years Participant Duration: 1-2 months Read Less

Gender:

ALL

Ages:

Between 18 years and 60 years

Trial Updated:

08/21/2025

Locations: National Institute on Drug Abuse, Baltimore, Maryland

Conditions: Nicotine Dependence

Learn More ›

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

NCT07023627

Recruiting

This study will evaluate the safety and efficacy of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer (PROC) With Cyclin E1 Overexpression.

Gender:

FEMALE

Ages:

Between 18 years and 99 years

Trial Updated:

08/21/2025

Locations: Usa Health Mitchell Cancer Institute, Mobile, Alabama +73 locations

Usa Health Mitchell Cancer Institute, Mobile, Alabama

Uams Winthrop P Rockefeller Cancer Institute, Little Rock, Arkansas

University of California, Los Angeles Medical Center, Los Angeles, California

Scripps Healthscripps Mercy Hospital Prebys Cancer Center, San Diego, California

Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida

Sylvester Comprehensive Cancer Center, Miami, Florida

Northeast Georgia Medical Center Gainesville, Gainesville, Georgia

Parkview Research Center, Fort Wayne, Indiana

Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana

Community Health Network, Inc., Indianapolis, Indiana

University of Iowa Hospital and Clinics, Iowa City, Iowa

Norton Cancer Institute, Louisville, Kentucky

Trials365, Llc, Shreveport, Louisiana

Greater Baltimore Medical Center, Baltimore, Maryland

Massachusetts General Hospital, Boston, Massachusetts

St Joseph Mercy Hospital-Gynecologic Oncology Clinic, Ypsilanti, Michigan

Minnesota Oncology-Minneapolis, Minneapolis, Minnesota

Washington University, Saint Louis, Missouri

St. Vincent Regional Hospital - West End Clinic, Billings, Montana

Methodist Hospital Methodist Estabrook Cancer Center, Omaha, Nebraska

John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, New Jersey

Laura and Isaac Perlmutter Cancer Center, New York, New York

University of Rochester, James P. Wilmot Cancer Center, Rochester, New York

State University of New York Upstate Medical Unive, Syracuse, New York

Oncology Hematology Care, Inc, Cincinnati, Ohio

The Mark H Zangmeister Cancer Center Ohio, Columbus, Ohio

Medical University of South Carolina, Charleston, South Carolina

Texas Oncology-Austin Center, Austin, Texas

Houston Methodist Cancer Center, Houston, Texas

Cancer Care Center of South Texas-Medical Center, San Antonio, Texas

Texas Oncology-Tyler, Tyler, Texas

Utah Cancer Specialists, Salt Lake City, Utah

Virginia Cancer Specialists, Pc, Fairfax, Virginia

Carilion Clinic, Roanoke, Virginia

West Virginia University, Morgantown, West Virginia

Froedtert & the Medical College of Wisconsin, Milwaukee, Wisconsin

Blacktown Cancer & Haematology Centre-Blacktown Hospital, Blacktown, New South Wales

Concord General Repatriation Hospital, Concord, New South Wales

Burnside War Memorial Hospital - the Brian Fricker Oncology Centre, Adelaide, South Australia

Hobart Hospital-Royal Hobart Hospital, Hobart, Tasmania

Cancer Research Sa (Crsa), Adelaide, Not set

Southern Oncology Clinical Research Unit, South Australia, Not set

Hopital Universitaire de Bruxelles (H.U.B)/ Academisch Ziekenhuis Brussel, Brussels, Not set

Cliniques Universitaires St Luc Ucl, Brussels, Not set

Az Groeninge Campus Kennedylaan, Kortrijk, Not set

Universitair Ziekenhuis Leuven, Leuven, Not set

Chu Liege, Liège, Not set

Hyogo Cancer Center, Akashi-shi, Not set

Saitama Medical University International Medical Center, Hidaka-shi, Not set

The Cancer Institute Hospital of Jfcr, Koto-ku, Not set

Kurume University Hospital, Kurume, Not set

Shikoku Cancer Center, Matsuyama-city, Not set

Hokkaido University Hospital, Sapporo, Not set

Shizuoka Cancer Center, Sunto-gun, Not set

Panoncology Trials, San Juan, Not set

Hospital Universitario Vall D'Hebron, Barcelona, Not set

Hospital Clinic de Barcelona (Hospital Clinic I Provincial), Barcelona, Not set

Instituto Catalan de Oncologia - Hospital Duran I Reynals, Barcelona, Not set

Institut Catala D'Oncologia Girona, Girona, Not set

Clinica Universidad de Navarra - Sede Madrid, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario Virgen de La Arrixaca, Múrcia, Not set

Hospital Clinico Universitario de Valencia (Instituto de Investigacion Sanitaria Incliva), Valencia, Not set

Istituto Oncologico Della Svizzera Italiana (Iosi) Di Bellinzona, Bellinzona, Not set

Hopital Du Valais-Geneva University Hospitals - Hug, Geneve, Not set

Centre Hospitalier Universitaire Vaudois Lausanne (Chuv) - Centre Du Cancer Lausanne-Batiment Hospit, Lausanne, Not set

Kantonsspital Baselland (Ksbl) - Standort Liestal - Medizinische Universitatsklinik, Liestal, Not set

Kantonsspital - Onkologisches Ambulatorium, St. Gallen, Not set

Western General Hospital - Lothian Health Board, Edinburgh, Not set

St Bartholomew'S Hospital, London, Not set

Guy'S Hospital - Guy'S & St Thomas' Nhs Foundation Trust, London, Not set

Royal Marsden Hospital (Sutton) - Royal Marsden Nhs Foundation Trust, London, Not set

Hammersmith Hospital - Imperial College Healthcare Nhs Trust, London, Not set

The Christie Nhs Foundation Trust, Manchester Greater, Not set

Conditions: Ovarian Cancer

Learn More ›

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

NCT06901531

Recruiting

Zolbetuximab is being studied in people with cancer in and around the stomach or where the food pipe (esophagus) joins the stomach, called gastroesophageal junction (GEJ) cancer. Zolbetuximab with chemotherapy may be used to treat stomach and GEJ cancer when the cancer cells do not have a protein called HER2 (human epidermal growth factor receptor 2) on their surface (HER2-negative) but do have a protein called Claudin 18.2 (Claudin 18.2-positive). Zolbetuximab is thought to work by attaching to the Claudin 18.2 protein in their tumor, which switches on the body's immune system to attack the tumor. Certain stomach and GEJ cancers may be treated with immunotherapy, which helps the body's immune system fight cancer. This study will give more information about how well zolbetuximab works when given with an immunotherapy medicine called pembrolizumab and chemotherapy. In this study, adults with stomach cancer or GEJ cancer will either be given zolbetuximab with pembrolizumab and chemotherapy or a placebo with pembrolizumab and chemotherapy. A placebo looks like zolbetuximab but doesn't have any medicine in it. The main aim of the study is to check how long people with stomach cancer and GEJ cancer live after treatment with zolbetuximab with pembrolizumab and chemotherapy compared to placebo with pembrolizumab and chemotherapy. Adults with locally advanced unresectable or metastatic stomach cancer or GEJ cancer can take part. Locally advanced means the cancer has spread to nearby tissue. Unresectable means the cancer cannot be removed by surgery. Metastatic means the cancer has spread to other parts of the body. A tumor sample (biopsy) of their cancer will have the Claudin 18.2 protein, PD-L1 protein, and be HER2-negative. They may have been previously treated with certain standard therapies. People cannot take part if they need to take medicines to suppress their immune system, have blockages or bleeding in their gut, have specific uncontrollable cancers such as symptomatic or untreated cancers in the nervous system, or have a specific heart condition, or infections. The study treatments are either zolbetuximab with pembrolizumab and chemotherapy, or placebo with pembrolizumab and chemotherapy. People who take part will receive just 1 of the study treatments by chance. The people in the study and the study doctors will not know who takes which of the study treatments. Study treatment will be given in 6-week (42-day) cycles. The study treatment is mainly given to people slowly through a tube into a vein. This is called an infusion. People will receive study treatment as follows: Zolbetuximab or placebo: 1 infusion every 2 or 3 weeks (2 or 3 infusions in a cycle) together with: Chemotherapy (1 of the following types of chemotherapy): 1. CAPOX (capecitabine and oxaliplatin): 1 infusion of oxaliplatin every 3 weeks (2 infusions in a cycle). People will also take 1 tablet of capecitabine twice a day for 2 weeks (14 days) at the start of each cycle (Day 1) and again in the middle of each cycle (Day 22). After 8 study treatments people will receive capecitabine only. 2. Modified FOLFOX6 or mFOLFOX6 (5-fluorouracil, folinic acid and oxaliplatin): 1 infusion every 2 weeks (3 infusions in a cycle). After 12 study treatments people will receive folinic acid and fluorouracil only, instead of mFOLFOX6. Pembrolizumab: 1 infusion every 3 or 6 weeks (1 or 2 infusions in a cycle). People can be in the study and will receive study treatment until their cancer worsens, they cannot tolerate the study treatment, or they need to start another cancer treatment. People may receive pembrolizumab for up to 2 years. People will visit the clinic on certain days to receive their study treatment and have health checks. The study doctors will check if people had any medical problems from taking zolbetuximab or the other study treatments. On some visits they will have scans to check for any changes in their cancer. People will have the option of giving a tumor sample if they stop treatment because their cancer has worsened. People will visit the clinic after they stop their study treatment. People will be asked about any medical problems and will have a health check. People will continue to have scans every 9 or 12 weeks to check for any changes in their cancer. They will have telephone health checks every 3 months. The number of visits and checks done at each visit will depend on the health of each person and whether they completed their study treatment or not. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/21/2025

Locations: Metro Minnesota Community Oncology Research Consortium (MMCORC), Saint Louis Park, Minnesota +21 locations

Conditions: Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma

Learn More ›

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion Alone or in Combination With Oral, IV, Subcutaneous Daratumumab; Lenalidomide; Dexamethasone; Carfilzomib

NCT06892522

Recruiting

Multiple myeloma (MM) is a cancer of the blood's plasma cells. The cancer is typically found in the bones and bone marrow (the spongy tissue inside of the bones) and can cause bone pain, fractures, infections, weaker bones, and kidney failure. Treatments are available, but MM can come back (relapsed) or may not get better (refractory) with treatment. This is a study to determine the safety, efficacy, and pharmacokinetics of Etentamig in adult participants with MM. Etentamig is an investigationa... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/21/2025

Locations: Colorado Blood Cancer Institute /ID# 273129, Denver, Colorado +7 locations

Conditions: Multiple Myeloma

Learn More ›

Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)

NCT01568697

Recruiting

Background: - Gum disease is a condition in which the tissue around the tooth root becomes swollen and infected. This condition can cause tooth loss if it is not treated. Who gets gum disease and how bad it will be depends on (1) the different bacteria in the mouth and (2) how the immune system of an individual handles these bacteria. Researchers want to look at the oral bacteria and genetic immune problems of different people to learn how these affect gum disease and other conditions of the mo... Read More

Gender:

ALL

Ages:

Between 7 years and 100 years

Trial Updated:

08/21/2025

Locations: National Institutes of Health Clinical Center, Bethesda, Maryland

Conditions: Immunosuppression, Periodontal Disease, Healthy Subjects, Healthy Volunteer

Learn More ›

A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis

NCT06832618

Recruiting

The purpose of the study is to assess the efficacy and safety of ruxolitinib cream in children and adolescents (6 to \<18 Years Old) with moderate atopic dermatitis.

Gender:

ALL

Ages:

Between 6 years and 17 years

Trial Updated:

08/21/2025

Locations: Clinical Research Center of Alabama, Birmingham, Alabama +94 locations

Clinical Research Center of Alabama, Birmingham, Alabama

Saguaro Dermatology, Phoenix, Arizona

National Jewish Health, Denver, Colorado

Cleaver Medical Group, Cumming, Georgia

Treasure Valley Medical Research, Boise, Idaho

Sneeze Wheeze and Itch Associates Llc, Normal, Illinois

Kindred Hair and Skin Center, Marriottsville, Maryland

Henry Ford Health System, Detroit, Michigan

University of Mississippi Medical Center, Jackson, Mississippi

Medisearch Clinical Trials, Saint Joseph, Missouri

Nyu Langone Health - Nyu Otolaryngology Associates, New York, New York

University of Rochester Medical Center, Rochester, New York

Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio

University of Texas Physicians - Bellaire Station, Bellaire, Texas

Medical College of Wisconsin, Milwaukee, Wisconsin

Cliniques Universitaires Ucl Saint-Luc, Brussels, Not set

Az Sint-Lucas, Gent, Not set

Universitair Ziekenhuis Gent, Gent, Not set

Les Viviers, Gilly, Not set

Centre Hospitalier Universitaire de Liege - Sart Tilman, Liege, Not set

Dermatologie Maldegem, Maldegem, Not set

Medical Centre 'Asklepii', Ood, Dupnitsa, Not set

Mhat Dr. Tota Venkova Ad, Gabrovo, Not set

Dcc 'Alexandrovska', Eood, Sofia, Not set

Diagnostic Consultative Center Xxviii, Sofia, Not set

Medical Center Assoc. Prof. Vasilev, Sofia, Not set

Dermatology Research Institute Inc., Calgary, Alberta

Laster Rejuvenation Clinics Edmonton D.T. Inc., Edmonton, Alberta

University of British Columbia (Ubc) - British Columbia Children'S Hospital (Bc Children'S Hospital), Vancouver, British Columbia

Winnipeg Clinic, Winnipeg, Manitoba

Leader Research, Hamilton, Ontario

Facet Dermatology, Toronto, Ontario

Centre de Recherche Saint-Louis, Montreal, Quebec

Chu Sainte-Justine, Montreal, Quebec

Skinsense Medical Research, Saskatoon, Saskatchewan

K. Papp Clinical Research, Ontario, Not set

Chu de Québec-Université Laval, Quebec, Not set

Skincare Studio Dermatology Centre, St. John's, Not set

Bordeaux Chu Hopital Saint - Andre, Bordeaux, Not set

Polyclinique Reims-Bezannes, Reims, Not set

Hopitaux Drome Nord, Romans-sur-isère, Not set

Fachklinik Bad Bentheim Dermatologie, Bad Bentheim, Not set

St. Josef-Hospital Universitaetsklinikum, Bochum, Not set

Universitatsklinikum Bonn Aoer, Bonn, Not set

Drk Krankenhaus Chemnitz-Rabenstein, Chemnitz, Not set

Universitaetsklinikum Carl Gustav Carus Tu Dresden, Dresden, Not set

Universitatsklinikum Frankfurt, Frankfurt, Not set

Universitatsmedizin Goettingen, Goettingen, Not set

Universitaetsklinikum Schleswig-Holstein - Campus Kiel, Kiel, Not set

Universitatsmedizin Der Johannes Gutenberg-Universitat Mainz Iii, Mainz, Not set

Universitatsklinikum Munster, Muenster, Not set

Clinexpert Kft., Budapest, Not set

Obudai Egeszsegugyi Centrum Kft., Budapest, Not set

Geomedical Orvosi Kft., Budapest, Not set

Semmelweis Egyetem, Budapest, Not set

Debreceni Egyetem Klinikai Kozpon Belgyogy Klinika, Debrecen, Not set

Bacs-Kiskun Varmegyei Oktatokorhaz, Kecskemet, Not set

Pecsi Tudomanyegyetem, Pecs, Not set

Szegedi Tudomanyegyetem Aok Szent-Gyorgyi Albert Klinikai Kozpont, Szeged, Not set

Azienda Ospedaliero Universitaria Policlinico G.Rodolico San Marco, Catania, Not set

Fondazione Irccs Ca Granda Ospedale Maggiore, Milano, Not set

Azienda Ospedaliera Universitaria Federico Ii, Napoli, Not set

Azienda Ospedale-Università Di Padova, Padova, Not set

Fondazione Policlinico Universitario Agostino Gemelli Irccs, Rome, Not set

Umc Utrecht, Utrecht, Not set

Centrum Badan Klinicznych Pi-House Sp. Z O.O., Gdansk, Not set

Gyncentrum Sp. Z O.O., Katowice, Not set

Centrum Medyczne All-Med Badania Kliniczne, Krakow, Not set

Diamond Clinic Sp. Z O.O., Krakow, Not set

Dermoklinika, Lodz, Not set

Clinical Best Solutions Sp. Z O.O. Sp. K., Lublin, Not set

Dermodent Centrum Medyczne Czajkowscy S.C., Osielsko, Not set

Twoja Przychodnia - Szczecinskie Centrum Medyczne, Szczecin, Not set

Mics Centrum Medyczne Toruń, Torun, Not set

Etg Warszawa, Warsaw, Not set

Mics Centrum Medyczne Warszawa Chlodna, Warszawa, Not set

High-Med Przychodnia Specjalistycza, Warszawa, Not set

Centrum Medyczne Evimed, Warszawa, Not set

Dermmedica Sp. Z O.O., Wrocław, Not set

Hospital General Unviersitario de Alicante, Alicante, Not set

Hospital de La Santa Creu I Sant Pau, Barcelona, Not set

Hospital Sant Joan de Deu, Esplugues de Llobregat, Not set

Hospital Universitario Virgen de Las Nieves, Granada, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario de La Paz, Madrid, Not set

Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda, Not set

Hospital Regional Universitario de Malaga, Malaga, Not set

Hospital de Manises, Manises, Not set

Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Not set

West Glasgow Ambulatory Care Hospital, Glasgow, Not set

St John'S Institute of Dermatology, London, Not set

University of Nottingham Health Service, Nottingham, Not set

Sheffield Childrens Hospital, Sheffield, Not set

Walsall Manor Hospital, Walsall, Not set

The Adam Practice, Wirral, Not set

Conditions: Atopic Dermatitis

Learn More ›

Treatment of Type 1 Diabetes With Anti-OX40L Bispecific With Anti-TNF Activity In a Single Nanobody® Molecule

NCT06812988

Recruiting

This is a randomized, placebo-controlled, parallel group, multicenter, double-blind Phase 2a, 2-arm study. The goal of this Phase 2a study is to assess safety and efficacy of SAR442970 in comparison to placebo to preserve β-cell function in participants with recently diagnosed type 1 diabetes (T1D) on insulin therapy. The study design comprises 2 parts: in Part A adult participants (18 to 35 years of age at screening) and in Part B adolescent and young adult participants (age range 12 to 21 ye... Read More

Gender:

ALL

Ages:

Between 12 years and 35 years

Trial Updated:

08/21/2025

Locations: Atlanta Diabetes Associates- Site Number : 8400006, Atlanta, Georgia +18 locations

Conditions: Type 1 Diabetes Mellitus

Learn More ›

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

NCT06875310

Recruiting

This is a trial to evaluate the efficacy, safety, and tolerability of adagrasib plus pembrolizumab plus platinum-doublet chemotherapy versus placebo plus pembrolizumab plus platinum-doublet chemotherapy in participants with previously untreated, locally advanced or metastatic NSCLC with KRAS G12C mutation

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/21/2025

Locations: Local Institution - 0347, Birmingham, Alabama +328 locations

Local Institution - 0347, Birmingham, Alabama

Local Institution - 0581, Fullerton, California

Local Institution - 0202, Long Beach, California

Local Institution - 0643, Newport Beach, California

Local Institution - 0666, Orange, California

Local Institution - 0623, Santa Barbara, California

Local Institution - 0442, Denver, Colorado

Local Institution - 0651, Gainesville, Florida

Local Institution - 0621, Palm Bay, Florida

Local Institution - 0377, Tamarac, Florida

Local Institution - 0647, Tampa, Florida

Local Institution - 0392, Fort Eisenhower, Georgia

Local Institution - 0031, Marietta, Georgia

Local Institution - 0665, Arlington Heights, Illinois

Local Institution - 0423, Munster, Indiana

Local Institution - 0366, Edgewood, Kentucky

Local Institution - 0566, Louisville, Kentucky

Local Institution - 0644, Shreveport, Louisiana

Local Institution - 0385, Columbia, Maryland

Local Institution - 0019, Boston, Massachusetts

Local Institution - 0437, Worcester, Massachusetts

Local Institution - 0618, White Plains, New York

Local Institution - 0624, Asheville, North Carolina

Local Institution - 0672, Salisbury, North Carolina

Local Institution - 0620, Columbus, Ohio

Local Institution - 0657, York, Pennsylvania

Local Institution - 0658, Greenville, South Carolina

Local Institution - 0652, Laredo, Texas

Local Institution - 0622, San Antonio, Texas

Instituto Alexander Fleming, Ciudad Autónoma de Buenos Aires, Buenos Aires

IDIM - Instituto de Investigaciones Metabólicas, Ciudad de Buenos Aires, Buenos Aires

Local Institution - 0584, Pilar, Buenos Aires

Hospital Italiano de Buenos Aires, ABB, Ciudad Autónoma De Buenos Aires

Local Institution - 0571, Buenos Aires, Ciudad Autónoma De Buenos Aires

Clinica Adventista Belgrano, Caba, Ciudad Autónoma De Buenos Aires

Sanatorio Plaza, Rosario, Santa Fe

Local Institution - 0126, Canberra, Australian Capital Territory

Tamworth Hospital, North Tamworth, New South Wales

Orange Hospital, Orange, New South Wales

Princess Alexandra Hospital, Brisbane, Queensland

Lyell McEwin Hospital, Elizabeth Vale, South Australia

Frankston Hospital, Frankston, Victoria

Northern Hospital, Melbourne, Victoria

Latrobe Regional Health, Traralgon, Victoria

Joondalup Health Campus, Joondalup, Western Australia

Klinikum Wels-Grieskirchen GmbH, Wels, Oberösterreich

Medizinische Universität Graz, Graz, Steiermark

Kepler Universitätsklinikum, Linz, Not set

Medizinische Universität Wien, Wien, Not set

Local Institution - 0673, Wien, Not set

UZ Brussel, Brussels, Bruxelles-Capitale, Région De

Cliniques universitaires Saint-Luc, Brussels, Bruxelles-Capitale, Région De

Jessa Ziekenhuis, Hasselt, Limburg

AZ Maria Middelares, Gent, Oost-Vlaanderen

UZ Leuven, Leuven, Vlaams-Brabant

Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman, Liège, Not set

Local Institution - 0257, Salvador, Bahia

Local Institution - 0242, Vitória, Espírito Santo

Local Institution - 0244, Belo Horizonte, Minas Gerais

Local Institution - 0235, Ijui, Rio Grande Do Sul

Local Institution - 0233, Porto Alegre, Rio Grande Do Sul

Local Institution - 0238, Santa Cruz do Sul, Rio Grande Do Sul

Local Institution - 0243, Porto Velho, Rondonia

Local Institution - 0237, Blumenau, Santa Catarina

Local Institution - 0245, Itajaí, Santa Catarina

Local Institution - 0240, Barretos, São Paulo

Local Institution - 0254, Sao Paulo, São Paulo

Local Institution - 0241, São Carlos, São Paulo

Local Institution - 0239, São José do Rio Preto, São Paulo

Local Institution - 0236, Rio de Janeiro, Not set

Local Institution - 0258, São Paulo, Not set

Local Institution - 0629, Panagyurishte, Pazardzhik

Local Institution - 0628, Sofia, Sofia (stolitsa)

Complex Oncology Center - Ruse EOOD, Ruse, Not set

Trakia Hospital, Stara Zagora, Not set

Local Institution - 0074, Halifax, Nova Scotia

Local Institution - 0559, Montreal, Quebec

Bradfordhill, Recoleta, Región Metropolitana De Santiago

FALP, Santiago, Región Metropolitana De Santiago

The First Afflilated Hospital of Bengbu Medical College, Bengbu, Anhui

Anhui Provincial Hospital, Hefei, Anhui

Beijing Cancer hospital, Beijing, Beijing

Local Institution - 0491, Beijing, Beijing

Local Institution - 0397, Beijing, Beijing

Chongqing University Cancer Hospital, Chongqing, Chongqing

Local Institution - 0362, Fuzhou Fujian, Fujian

The First Affiliated hospital of Xiamen University, Xiamen, Fujian

The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong

Cancer Hospital of Shantou University Medical College, Shantou, Guangdong

Cancer Hospital Chinese Academy of Medical Sciences. Shenzhen Center, Shenzhen, Guangdong

ShenZhen People's Hospital, Shenzhen, Guangdong

Guangxi Medical University Affiliated Tumor Hospital, Nanning, Guangxi

Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei

Harbin Medical University Cancer Hospital, Harbin, Heilongjiang

Nanyang City Center Hospital, Nanyang, Henan

The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan

Tongji Hospital Tongji Medical,Science & Technology, Wuhan, Hubei

Local Institution - 0398, Changsha, Hunan

Local Institution - 0371, Nanjing, Jiangsu

The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu

Northern Jiangsu People's Hospital, Yangzhou, Jiangsu

The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

The First Hospital of Jilin University, Changchun, Jilin

The First Hospital of China Medical University, Shenyang, Liaoning

Shengjing Hospital of China Medical University, Shenyang, Liaoning

Local Institution - 0493, Shenyang, Liaoning

Shandong Cancer Hospital, Jinan, Shandong

LinYi Cancer Hospital, Linyi, Shandong

Local Institution - 0470, Shanghai, Shanghai

Local Institution - 0381, Shanghai, Shanghai

Shanxi Cancer Hospital, Taiyuan, Shanxi

West China Hospital, Sichuan University, Cheng Du, Sichuan

Sichuan Cancer hospital, Chengdu, Sichuan

Tianjin Medical University General Hospital, Tianjin, Tianjin

Local Institution - 0462, Hangzhou, Zhejiang

Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang

Zhejiang Cancer Hospital, Hangzhou, Zhejiang

Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang

Shanghai East Hospital, Shanghai, Not set

Local Institution - 0580, Medellín, Antioquia

Local Institution - 0171, Rionegro, Antioquia

Local Institution - 0191, Puerto Colombia, Atlántico

Local Institution - 0253, Valledupar, Cesar

Local Institution - 0167, Montería, COR

Local Institution - 0671, Bogota, Cundinamarca

Local Institution - 0189, Bogotá, Distrito Capital De Bogotá

Local Institution - 0170, Floridablanca, Santander

Local Institution - 0173, Cali, Valle Del Cauca

Local Institution - 0619, Dubrovnik, Dubrovačko-neretvanska Županija

Local Institution - 0664, Rijeka, Primorsko-goranska Županija

Local Institution - 0639, Split, Splitsko-dalmatinska Županija

Local Institution - 0567, Osijek, Not set

Local Institution - 0585, Zagreb, Not set

Local Institution - 0159, Mulhouse, Alsace

Centre François Baclesse, Caen, Calvados

Centre Georges François Leclerc, Dijon, Côte-d'Or

CHRU de Brest, Brest, Finistère

Institut Régional du Cancer Montpellier, Montpellier, Hérault

Chu Grenoble Alpes, La Tronche, Isère

Local Institution - 0560, Angers, Maine-et-Loire

Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois, Vandoeuvre lès Nancy, Meurthe-et-Moselle

Local Institution - 0636, Marseille, Provence-Alpes-Côte-d'Azur

CHU d'Amiens-Picardie - Hôpital Sud, Amiens, Somme

Gustave Roussy, Villejuif, Val-de-Marne

Hôpital Ambroise Paré, Boulogne-Billancourt, Not set

Chu Gabriel Montpied, Clermont-Ferrand, Not set

Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren, Limoges, Not set

Assistance Publique Hôpitaux de Marseille - Hôpital Nord, Marseille, Not set

Local Institution - 0133, Paris, Not set

Hopitaux Universitaires Paris Centre-Hopital Cochin, Paris, Not set

Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes, Saint-Herblain, Not set

Klinikum Esslingen, Esslingen, Baden-Württemberg

Local Institution - 0670, Ulm, Baden-Württemberg

Klinikum der Ludwig-Maximilians-Universitaet Muenchen, München, Bayern

Centrum für Hämatologie und Onkologie Bethanien, Frankfurt, Hessen

Local Institution - 0535, Gießen, Hessen

Praxis Onkologie am Raschplatz, Hannover, Niedersachsen

Pius Hospital Oldenburg, Oldenburg, Niedersachsen

Evangelisches Krankenhaus Herne - Eickel, Herne, Nordrhein-Westfalen

Klinikum Köln-Merheim, Köln, Nordrhein-Westfalen

Local Institution - 0522, Halle, Sachsen-Anhalt

Malteser Krankenhaus St. Franziskus-Hospital, Flensburg, Schleswig-Holstein

Local Institution - 0524, Gera, Thüringen

Universitätsklinikum Jena, Jena, Thüringen

Vivantes Klinikum Neukölln, Berlin, Not set

Evangelische Lungenklinik Berlin, Berlin, Not set

Local Institution - 0675, Halle, Not set

Local Institution - 0528, Hemer, Not set

Local Institution - 0517, Stuttgart, Not set

Universitaetsklinikum Wuerzburg, Wuerzburg, Not set

Errikos Dunant Hospital Center, Athens, Attikí

Thoracic General Hospital of Athens "I Sotiria", Athens, Attikí

University General Hospital of Larissa, Larissa, Thessalía

Queen Mary Hospital, Hksar, Not set

Local Institution - 0144, Gyöngyös, Heves

Local Institution - 0157, Tatabánya, Komárom-Esztergom

Local Institution - 0593, Kaposvár, Somogy

Local Institution - 0143, Farkasgyepu, Veszprém

Local Institution - 0151, Budapest, Not set

Local Institution - 0140, Budapest, Not set

Petz Aladar Egyetemi Oktato Korhaz, Győr, Not set

Local Institution - 0222, Visakhapatnam, Andhra Pradesh

Local Institution - 0312, New Delhi, Delhi

Local Institution - 0511, New Delhi, Delhi

Local Institution - 0135, New Delhi, Delhi

Local Institution - 0136, Ahmedabad, Gujarat

Local Institution - 0230, Ahmedabad, Gujarat

Local Institution - 0155, Thiruvananthapuram, Kerala

Local Institution - 0154, Mumbai, Maharashtra

Local Institution - 0226, Bhubaneswar, Odisha

Local Institution - 0224, Madurai, Tamil Nadu

Local Institution - 0663, Hyderabad, Telangana

Local Institution - 0153, Varanasi, Uttar Pradesh

Local Institution - 0161, Howrah, West Bengal

Local Institution - 0221, Kolkata, West Bengal

Local Institution - 0661, Hyderabad, Not set

Local Institution - 0102, Cork, Not set

Mater Private Hospital - Dublin, Dublin, Not set

St. James's Hospital, Dublin, Not set

Local Institution - 0100, Dublin, Not set

Beaumont Hospital, Dublin, Dublin, Not set

Rabin Medical Center, Petah Tikva, HaMerkaz

Sheba Medical Center, Ramat Gan, HaMerkaz

Yitzhak Shamir Medical Center, Zerifin, HaMerkaz

Hadassah Medical Center, Jerusalem, Yerushalayim

Local Institution - 0613, Haifa, Ḥeifā

IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Emilia-Romagna

A.O.R.N. Ospedale dei Colli - Monaldi V., Naples, Napoli

Local Institution - 0070, Orbassano, Piemonte

Local Institution - 0071, Bari, Puglia

Local Institution - 0068, Rome, Roma

Azienda Ospedaliera Universitaria Careggi, Firenze, Toscana

Ospedale San Martino, Genova, Not set

Local Institution - 0073, Padova, Not set

Local Institution - 0156, Parma, Not set

Local Institution - 0543, Pavia, Not set

Local Institution - 0556, Varese, Not set

Local Institution - 0607, Nagoya, Aichi

Local Institution - 0305, Nagoya, Aichi

Local Institution - 0298, Sapporo, Hokkaido

Local Institution - 0304, Kanazawa, Ishikawa

Local Institution - 0302, Sagamihara, Kanagawa

Local Institution - 0369, Yokohama, Kanagawa

Local Institution - 0301, Sendai, Miyagi

Local Institution - 0306, Kashihara, Nara

Local Institution - 0368, Kurashiki, Okayama

Local Institution - 0642, Hirakata, Osaka

Local Institution - 0303, Hidaka, Saitama

Local Institution - 0300, Ina-machi, Saitama

Local Institution - 0606, Hamamatsu, Shizuoka

Local Institution - 0299, Shimotsuga, Tochigi

Local Institution - 0674, Bunkyo ku, Tokyo

Local Institution - 0343, Toyoma, Toyama

Local Institution - 0542, Iwakuni, Yamaguchi

Local Institution - 0307, Akashi, Not set

Local Institution - 0346, Aomori, Not set

Local Institution - 0310, Fukuoka, Not set

Local Institution - 0367, Fukushima, Not set

Local Institution - 0308, Kumamoto, Not set

Local Institution - 0297, Osaka, Not set

Local Institution - 0309, Osaka, Not set

Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do [Chungbuk]

Gachon University Gil Medical Center, Namdong-gu, Incheon-gwangyeoksi [Incheon]

Pusan National University Yangsan Hospital, Yangsan, Kyǒngsangnam-do

Pusan National University Hospital, Busan, Pusan-Kwangyǒkshi

Severance Hospital, Yonsei University Health System, Seoul, Seoul-teukbyeolsi [Seoul]

Konkuk University Medical Center, Seoul, Seoul-teukbyeolsi [Seoul]

The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

Korea University Guro Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0583, Saltillo, Coahuila

Local Institution - 0176, Mexico City, DIF

Local Institution - 0579, Pachuca, Hidalgo

Local Institution - 0178, Guadalajara, Jalisco

Local Institution - 0591, Monterrey, Nuevo León

Local Institution - 0175, Chihuahua, Not set

Local Institution - 0181, Puebla, Not set

Local Institution - 0638, Puebla, Not set

Local Institution - 0180, Veracruz, Not set

Local Institution - 0615, Maastricht, Limburg

Nederlands Kanker Instituut Antoni van Leeuwenhoek (NKI AVL), Amsterdam, Noord-Holland

Local Institution - 0205, Wrocław, Dolnośląskie

Uniwersytecki Szpital Kliniczny Nr 4 w Lublinie, Lublin, Lubelskie

Szpital Specjalistyczny im. Henryka Klimontowicza, Gorlice, Małopolskie

Pratia MCM Krakow, Kraków, Małopolskie

Med-Polonia Sp. z o. o., Poznan, Wielkopolskie

Centrum Onkologii im. Prof. Franciszka Lukaszczyka, Bydgoszcz, Not set

Local Institution - 0078, Katowice, Not set

Szpital Specjalistyczny w Prabutach Spolka z o.o., Prabuty, Not set

Local Institution - 0509, Lisbon, Lisboa

Instituto Portugês de Oncologia de Coimbra Francisco Gentil, Coimbra, Not set

Centro Hospitalar do Porto - Hospital de Santo António, Porto, Not set

SC Memorial Healthcare International SRL, Bucharest, București

Institutul Oncologic Bucuresti, Bucharest, București

Cardiomed SRL Cluj-Napoca, Cluj-Napoca, Cluj

SC Radiotherapy Center Cluj SRL, Florești, Cluj

Ovidius Clinical Hospital OCH, Ovidiu, Constanța

Centrul de Oncologie "Sfântul Nectarie", Craiova, Dolj

Spitalul Municipal Schuller Ploiești, Ploiești, Prahova

Cabinet Medical Oncomed, Timișoara, Timiș

Institutul Oncologic Cluj, Cluj, Not set

Affidea Constanța, Constanța, Not set

S.C. Centrul de Oncologie Euroclinic S.R.L., Iași, Not set

Institutul Regional de Oncologie, Iași, Not set

Local Institution - 0614, Jeddah, Makkah Al Mukarramah

Local Institution - 0602, Riyadh, Not set

Local Institution - 0562, Riyadh, Not set

Local Institution - 0499, A Coruña, A Coruña [La Coruña]

Local Institution - 0506, Santiago de Compostela, A Coruña [La Coruña]

Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]

Local Institution - 0497, Hospitalet, Barcelona [Barcelona]

Local Institution - 0505, Barcelona, Catalunya [Cataluña]

Hospital Son Llàtzer, Palma, Illes Balears [Islas Baleares]

Hospital General Universitario Gregorio Marañon, Madrid, Madrid, Comunidad De

Hospital Universitario Ramón y Cajal, Madrid, Madrid, Comunidad De

Hospital Universitario 12 de Octubre, Madrid, Madrid, Comunidad De

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid, Comunidad De

Local Institution - 0669, Pontevedra, Pontevedra [Pontevedra]

Hospital Arnau de Vilanova, Valencia, València

Hospital Clinico San Carlos, Madrid, Not set

H.R.U Málaga - Hospital General, Málaga, Not set

Hospital Universitario Virgen Del Rocio, Sevilla, Not set

Local Institution - 0495, València, Not set

Kantonsspital Münsterlingen - Spital Thurgau AG, Münsterlingen, Not set

Chi Mei Hospital - Liouying Branch, Tainan City, Tainan

Tri-Service General Hospital, Taipei City, Taipei

Taipei Medical University Shuang Ho Hospital, New Taipei, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Local Institution - 0565, Muang, Khon Kaen

Local Institution - 0563, Bangkok, Krung Thep Maha Nakhon

Local Institution - 0564, Hatyai, Songkhla

Local Institution - 0548, Stanbul, İstanbul

Local Institution - 0199, Izmir, Karsiyaka, İzmir

Local Institution - 0197, Adana, Not set

Local Institution - 0201, Ankara, Not set

Local Institution - 0194, Ankara, Not set

Local Institution - 0198, Ankara, Not set

Local Institution - 0550, Istanbul, Not set

Local Institution - 0549, Istanbul, Not set

Local Institution - 0200, Izmir, Not set

University College London Hospital, London, London, City Of

Guy's & St Thomas' NHS Foundation Trust, London, London, City Of

Heartlands Hospital, Birmingham, Not set

Local Institution - 0545, Guildford, Not set

The Royal Surrey County Hospital, Guildford, Not set

Local Institution - 0093, Manchester, Not set

Conditions: Carcinoma, Non-Small-Cell Lung

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A Study to Determine the Safety and Tolerability of AG-236 and How it is Absorbed, Broken Down, and Eliminated From the Body in Healthy Participants

NCT07075640

Recruiting

The primary purpose of this study is to assess the safety and tolerability of a single dose of AG-236 administered subcutaneously in healthy participants.

Gender:

ALL

Ages:

Between 18 years and 55 years

Trial Updated:

08/21/2025

Locations: Fortrea Clinical Research Unit Inc., Madison, Wisconsin

Conditions: Healthy Participants

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Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

NCT04947254

Recruiting

This phase II trial studies the effect of androgen ablation therapy with or without niraparib after standard of care radiation therapy in treating patients with prostate cancer that has not spread to other parts of the body (localized) or that has spread to nearby tissue or lymph nodes (locally advanced). Androgen ablation therapy (also known as hormone therapy) lowers the levels of male hormones called androgens in the body. Androgens stimulate prostate cancer cells to grow. There are 2 types o... Read More

Gender:

MALE

Ages:

18 years and above

Trial Updated:

08/21/2025

Locations: M D Anderson Cancer Center, Houston, Texas

Conditions: Prostate Carcinoma, Stage IIC Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8

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Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress

NCT07138443

Recruiting

This study aims to evaluate the influence of acute oral melatonin supplementation on cardiovascular and skin temperature responses to mental stress. The hypothesis is that acute melatonin will lead to reduced cardiovascular and skin temperature responsiveness to acute mental stress.

Gender:

ALL

Ages:

Between 18 years and 70 years

Trial Updated:

08/21/2025

Locations: Baylor University Autonomic Function Laboratory, Waco, Texas

Conditions: Stress, Mental Stress

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A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

NCT05050136

Recruiting

The purpose of this clinical research study is to learn more about the use of the study medicine, volixibat, for the treatment of pruritus (itching) associated with Primary Biliary Cholangitis (PBC), and to assess the possible impact on the disease progression of PBC.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/21/2025

Locations: Southern California Research Center, Coronado, California +100 locations

Southern California Research Center, Coronado, California

Cedars Sinai Medical Center, Los Angeles, California

University of Colorado, Aurora, Colorado

Covenant Metabolic Specialists, Fort Myers, Florida

UF Hepatology Research at CTRB, Gainesville, Florida

UF Health Gastroenterology- Emerson, Jacksonville, Florida

IHS Health, Kissimmee, Florida

Schiff Center for Liver Diseases, Miami, Florida

Advanced Research Institute, Inc, New Port Richey, Florida

Covenant Research and Clinics, LLC, Sarasota, Florida

Tampa General Hospital, Tampa, Florida

Southeast Clinical Research Center, Dalton, Georgia

Northwestern University, Chicago, Illinois

Loyola University Health System - Loyola Outpatient Center, Maywood, Illinois

University of Iowa Hospitals & Clinics, Iowa City, Iowa

Ochsner Clinic Foundation-Baton Rouge, Baton Rouge, Louisiana

LSU Health Science Center Shreveport, Shreveport, Louisiana

Beth Israel Deaconess, Boston, Massachusetts

Mayo Clinic, Rochester, Minnesota

Jackson Liver and GI Specialists, Jackson, Mississippi

CHI Health Clinic (Alegent Creighton Clinic)- Gastroenterology-Bergan, Omaha, Nebraska

Science 37, Inc (Remote-homebased Telemedicine), Morrisville, North Carolina

Cleveland Clinic - Main Campus, Cleveland, Ohio

Einstein Healthcare Network - Einstein Medical Center, Philadelphia, Pennsylvania

Methodist Le Bonheur Healthcare, Memphis, Tennessee

Galen Medical Group, P.C, Tennessee, Tennessee

Amel Med LLC, Austin, Texas

Soma Clinical Trials, Denison, Texas

Liver Associates of Texas, Houston, Texas

Velocity Clinical Research, Waco, Texas

University of Utah Health Care, Salt Lake City, Utah

MedStar Health Research Institute, Fairfax, Virginia

Bon Secours Liver Institute of Hampton Roads Mary Immaculate Hospital, Newport News, Virginia

Bon Secours Richmond Community Hospital LLC d/b/a Bon Secours Liver Institute of Richmond, Richmond, Virginia

Liver Institute Northwest, Seattle, Washington

Hospital de Alta Complejidad En Red El Cruce, Florencio Varela, Buenos Aires

Hospital Provincial Del Centenario, Rosario, Santa Fe

Glenny Corp S.A, Caba, Not set

Universitair Ziekenhuis Antwerpe UZA, Antwerp, Not set

Cliniques Universitaires Saint-Luc, Brussel, Not set

UZ Gent, Gent, Not set

Centro de Pesquisa Clínica da Bahiana Saúde, Salvador, Bahia

Hospital Das Clínicas Da Ufg, Goiânia, Goiás

Centro de Pesquisas Clínicas do HC/UFMG-EBSERH, Belo Horizonte, Minas Gerais

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS

Fundação Oswaldo Ramos, São Paulo, Not set

Gordon and Leslie Diamond Health Care Centre, Division of Gastroenterology, Vancouver, British Columbia

University Hospital, LHSC, London, Ontario

McGill University Health Centre, Montréal, Quebec

University of Alberta, Edmonton, Not set

Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, Fujian

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei

The First Hospital of Jilin University, Changchun, Jilin

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang

Beijing Youan Hospital, Capital Medical University, Beijing, Not set

Beijing Friendship Hospital, Capital Medical University, Beijing, Not set

Sir Run Run Shaw Hospital -Zhejiang University School of Medicine, Hangzhou, Not set

CHU Grenoble - Hôpital MICHALLON, Grenoble, Not set

Hopital Claude Huriez-Digestive system disease clinic, Lille, Not set

CHU de NICE- Hospital L'Archet 2, Nice, Not set

Hospital Saint Antoine, Paris, Not set

Nouvel Hospital Civil, Strasbourg, Not set

Hospital Paul Brousse- APHP, Villejuif, Not set

Klinikum Chemnitz gGmbH, Chemnitz, Not set

Universitätsklinikum Frankfurt am Main, Frankfurt, Not set

Medizinische Hochschule Hannover (MHH), Hanover, Not set

Universitätsklinikum Schleswig-Holstein, Kiel, Not set

University Hospital Munster, Münster, Not set

University Hospital Tübingen Medical clinic, Tubingen, Not set

St. Josefs-Hospital Wiesbaden, Wiesbaden, Not set

Hillel Yaffe Medical Center, Hadera, Not set

Rambam Medical Center, Haifa, Not set

Carmel Medical Center, Haifa, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

Hadassah Medical Center - Ein Karem, Liver Institute Kiryat Hadassah POB 12000, Jerusalem, Not set

Galilee Medical Center, Nahariyya, Not set

Rabin Medical Center, Petach Tikva, Not set

Sheba Medical Center, Ramat Gan, Not set

The Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

Universita Politecnica delle Marche- Ospedali Riuniti, Ancona, Not set

Fondazione Ca Granda, Milano, Not set

ASST Grande Ospedale Metropolitano Niguarda, Milano, Not set

Fondazione IRCCS San Gerardo dei Tintori, Monza, Not set

Azienda Ospedale-Università di Padova, Padova, Not set

Azienda Ospedaliero Universitaria Pisana (AOUP), Pisa, Not set

Istituto Clinico Humanitas, Rozzano, Not set

National Hospital Organization Nagasaki Medical Center, Ōmura, Nagasaki

Ehime University Hospital, Ehime, Not set

Toranomon Hospital, Tokyo, Not set

Amstedam University Medical Centers, Amsterdam, Not set

Radboudumc, Nijmegen, Not set

Erasmus medical center, Rotterdam, Not set

Hospital Clínic de Barcelona, Barcelona, Not set

Hospital Universitari Parc Tauli, Barcelona, Not set

Hospital General Universitario Gregorio Maranon, Madrid, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

University Hospital Zurich(USZ), Zürich, Not set

University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire

Belfast Health & Social Care Trust (BHSCT) Royal Victoria Hospital, Belfast, Not set

King's College Hospital NHS Foundation Trust, London, Not set

Nottingham University Hospitals NHS Trust, Nottingham, Not set

Conditions: Primary Biliary Cholangitis, PBC

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