Willingness to Participate in a Trial Comparing Standard Genetic Counseling Versus Personalized Genetic Counseling
NCT05126810
Recruiting
This study evaluates patients willingness to participate in a trial comparing standard genetic counseling versus personalized genetic counseling. Collecting information from patients may help researchers learn why patients may or may not take part in the future study that compares standard genetic counseling to personalized genetic counseling.
Gender:
ALL
Ages:
All
Trial Updated:
04/29/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Li-Fraumeni Syndrome
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Impact of "Teaching the Teachers" Concept on Global Education and Application of Hepatocellular Carcinoma Diagnosis Guidelines
NCT05143619
Recruiting
This study evaluates a concept called 'Teaching the Teachers' and whether it is helpful in disseminating guidelines on the national and international levels. "Teaching the Teachers" involves teaching the guidelines to experts who later teach the same guidelines to other radiologists, trainees, and physicians to assume the teacher's role and disseminate the guidelines and so on.
Gender:
ALL
Ages:
All
Trial Updated:
04/29/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Hepatocellular Carcinoma
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Comparing Two Ways to Manage Head and Neck Lymphedema
NCT05182229
Recruiting
This randomized clinical trial aims to compare clinic-based CDT and home-based (a hybrid model) CDT on changes in the severity of lymphedema, symptom burden, functional status, and healthcare utilization in HNC survivors with lymphedema.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/29/2025
Locations: Jefferson Cherry Hospital Jefferson Health, Cherry Hill, New Jersey +5 locations
Conditions: Head and Neck Cancer, Lymphedema
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Healthy Living After Knee Replacement
NCT05190666
Recruiting
The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to a chronic disease self-management program.
Gender:
ALL
Ages:
All
Trial Updated:
04/29/2025
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Arthroplasty, Overweight and Obesity
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Liver Cancer Prevention Randomized Control Trial
NCT05196867
Recruiting
To determine the effectiveness of a behaviorally-based tailored disease management intervention in patients with fibrosis or steatosis and risk factors for cirrhosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/29/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Liver Diseases, Fibrosis, Liver, Cirrhosis, Liver
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Understanding and Addressing Disparities in Cancer Therapy Induced Inflammation and Associated Endothelial Dysfunction
NCT05223322
Recruiting
Very little is understood about the off-target vascular mechanisms of anti-cancer drug toxicity and the impact of exercise on these changes. Much of what has been learned about molecular pathways regulating vascular endothelial function has been established by logical expansion of knowledge obtained through experimental studies (e.g., discovery of endothelium-derived relaxing factor/nitric oxide). Within the last 10 years technological advancements of -omics approaches, such as RNA-sequencing an... Read More
Gender:
FEMALE
Ages:
Between 18 years and 100 years
Trial Updated:
04/29/2025
Locations: University of Illinois Chicago, Chicago, Illinois +1 locations
Conditions: Breast Cancer
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Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease
NCT05266417
Recruiting
This study will be evaluating the safety and efficacy of insulin and glutathione in subjects with Parkinson's Disease compared to placebo.
Gender:
ALL
Ages:
Between 30 years and 85 years
Trial Updated:
04/29/2025
Locations: Institute for Neuroimmune Medicine, Davie, Florida +1 locations
Conditions: Parkinson Disease
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Patient Derived Preclinical Models
NCT05324553
Recruiting
Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinical models. This study is being done to collect samples of tumor tissues, matched normal tissue when possible, and approximately 50 mL of blood.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/29/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Cancer
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Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
NCT05378347
Recruiting
The purpose of this trial is to generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft Systems verses Gore Excluder / Excluder Conformable AAA Endoprosthesis in subjects with Abdominal Aortic Aneurysms. Subjects are randomized and imaging collected at all follow-up time points to assess the primary endpoint.
Gender:
ALL
Ages:
20 years and above
Trial Updated:
04/29/2025
Locations: Loma Linda University Medical Center, Loma Linda, California +66 locations
Conditions: Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder), Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
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Post-Exablate Pregnancy Outcomes Registry Study: Exablate Treatment of Symptomatic Uterine Fibroids
NCT05386615
Recruiting
The goal of this Registry Study is to capture clinical pregnancy outcomes and fibroid treatment background data for any subject post-Exablate treatment for their symptomatic fibroids.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
04/29/2025
Locations: UCLA, Los Angeles, California +5 locations
Conditions: Uterine Fibroid
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The Decision To Enroll In Therapeutic Clinical Trials In A Pediatric Cancer Clinical Network
NCT05454618
Recruiting
The focus of this study is to learn about the factors that parents consider when making a decision for their child to participate or not in a clinical treatment research study.
Gender:
ALL
Ages:
All
Trial Updated:
04/29/2025
Locations: St. Jude Children's Research Hospital, Memphis, Tennessee
Conditions: Knowledge, Attitudes, Practice
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Exercise in Metastatic Breast Cancer: EMBody
NCT05468034
Recruiting
The purpose of this study is to study exercise in a novel population with indolent MBC (no progression on current therapy in prior 12 months and not receiving cytotoxic chemotherapy). The study team hypothesizes that delivering virtual, supervised, progressive intensity aerobic and resistance training exercise for 16 weeks in this population will significantly improve 1) cardiorespiratory fitness, functional status, and sarcopenia (low muscle mass), all established predictors of survival, and 2)... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/29/2025
Locations: Yale Cancer Center, New Haven, Connecticut +5 locations
Conditions: Breast Cancer, Indolent Metastatic Breast Cancer
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