Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Chemotherapy
Recruiting
This phase III trial compares BBT-CI to HEAL for the reduction of insomnia in patients with stage I-IV cancer who are receiving cancer treatment. Cancer treatment can cause side effects such as sleep problems. Sleep problems such as insomnia, are common for cancer patients. Insomnia can be described as difficulty falling asleep, waking up many times during the night or waking up earlier than patient would like. Insomnia can increase fatigue and worsen quality of life. This trial may help researc... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2024
Locations: Kingman Regional Medical Center, Kingman, Arizona +129 locations
Conditions: Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Effect of Percussive Massage on Skeletal Muscle During Limb Immobilization
Recruiting
The primary aims of this study are to determine the effect of percussive massage (30 min/session, 2 sessions/day, daily) during 10 days of unilateral limb immobilization on preserving muscle, vascular, and mitochondrial function. The following hypotheses will be tested: Hypothesis 1: Percussive massage will attenuate the loss of size, strength and endurance over the immobilization period compared to the control group, as measured by MRI, maximal isometric and isokinetic force production and mus... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
08/12/2024
Locations: Brigham Young University, Provo, Utah
Conditions: Massage Therapy, Muscular Atrophy
Posterior Rectus Sheath Hiatal Augmentation in Paraesophageal Hernia Repair
Recruiting
This study will be a prospective observation study of the use of PoRSHA for repair in patients with challenging paraesophageal hernias. One of the most challenging problems facing foregut surgeons is the large and complex paraesophageal hernia (PEH) repair in the older patient. The investigator has demonstrated good outcomes and durability with the initial use of a novel permanent autologous vascularized biologic fascial flap to reconstruct the diaphragmatic hiatus following standard hiatal her... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2024
Locations: The University of Chicago, Chicago, Illinois
Conditions: Paraesophageal Hernia
Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
Recruiting
The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features. .
Gender:
ALL
Ages:
All
Trial Updated:
08/12/2024
Locations: Beckman Laser Institute Medical Clinic, Irvine, California
Conditions: Skin Lesion
Individualized Vocational and Educational Support and Training for Clinical High Risk for Psychosis (InVEST)
Recruiting
The purpose of this study is to test the efficacy of InVEST (Individualized Vocational and Educational Support and Training) for CHR-P (clinical high risk for psychosis) to address specific role functioning difficulties associated with the CHR-P phase. Our specific goals are: 1. Part 1: Preliminary open trial of InVEST (n = 8) to collect preliminary feasibility and acceptability data by providing the intervention, administering assessments, and collecting focus group and self-report feedback fr... Read More
Gender:
ALL
Ages:
Between 12 years and 22 years
Trial Updated:
08/12/2024
Locations: Beth Israel Deaconess Medical Center/ Massachusetts Mental Health Center, Boston, Massachusetts
Conditions: Clinical High Risk for Psychosis
Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers
Recruiting
The purpose of this research study is to find out about the effects of a drug called mavoglurant on alcohol consumption.
Gender:
ALL
Ages:
Between 21 years and 50 years
Trial Updated:
08/12/2024
Locations: Connecticut Mental Health Center (SAC and SATU), New Haven, Connecticut +1 locations
Conditions: Alcohol Consumption, Heavy Drinker, Alcohol Use Disorder (AUD)
Randomized Clinical Trial of Supplementing Brief Psychotherapy With a Mobile App
Recruiting
The aim of this study is to determine whether learning three skills for managing negative emotions and receiving reminders via smartphone to practice these skills reduces how often and how intensely one experiences emotional distress and suicidal thoughts.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2024
Locations: Rutgers University Behavioral Healthcare, Piscataway, New Jersey
Conditions: Suicidal Ideation, Suicide, Suicide Attempt
Evaluation of the PACE/PACENET BHL Clinical Program
Recruiting
The SUpporting Seniors Receiving Treatment And INtervention (SUSTAIN) program is a telephone-based clinical service designed to help identify and manage behavioral health issues among PACE/PACENET enrollees. The purpose of the current project is to a) explore moderators of treatment response among beneficiaries in the SUSTAIN Clinical Program and b) to evaluate the sustained clinical effects of the program.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
08/12/2024
Locations: Department of Psychiatry (Center for Psychotherapy Research), University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Depression, Anxiety, Pain, Chronic
Clinical Efficacy and Human Factors Validation Testing of the Erchonia EVRL for Providing Temporary Relief of Diabetic Peripheral Neuropathy Foot Pain
Recruiting
The purpose of this clinical study is to determine the effectiveness of the Erchonia® EVRL™, manufactured by Erchonia Corporation (the Company), in providing prescription home use application for temporary relief of diabetic neuropathy foot pain in individuals diagnosed with diabetic neuropathy by a suitably qualified and licensed health professional.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2024
Locations: CiC Foot & Ankle, Phoenix, Arizona +3 locations
Conditions: Neuropathy, Diabetic, Neuropathy;Peripheral, Neuropathy, Painful
Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning
Recruiting
The goal of this observational study is to test a reciprocal relationship between statistical learning and the development of language and literacy in first-graders with autism and their non-autistic peers. The main questions it aims to answer are: 1. whether children's statistical learning abilities can predict their long-term improvement of language and literacy skills in school; 2. how children's brains automatically learn patterns from speech and prints; 3. whether children's learning in th... Read More
Gender:
ALL
Ages:
Between 72 months and 90 months
Trial Updated:
08/12/2024
Locations: Northeastern University, Boston, Massachusetts +1 locations
Conditions: Autism Spectrum Disorder, Language Development, Literacy
Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia
Recruiting
Recent findings suggest that sleep disruption may contribute to the generation and maintenance of neuropsychiatric symptoms including anxiety, depression, agitation, irritation, and apathy while treating sleep disruption reduces these symptoms. Impairments in the neural systems that support emotion regulation may represent one causal mechanism mediating the relationship between sleep and emotional distress. However, this model has not yet been formally tested within a sample of individuals with... Read More
Gender:
ALL
Ages:
Between 50 years and 90 years
Trial Updated:
08/12/2024
Locations: Andrea Goldstein-Piekarski, PhD, Palo Alto, California
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Neuropsychiatric Symptoms, Sleep Disturbance
Mental Health in Primary Care
Recruiting
The goal of this study is to evaluate in an effectiveness-implementation type I hybrid trial, an enhanced version of eHealth Familias Unidas for reducing depressive, anxious symptoms and suicide behavior in Hispanic youth. The study will use a randomized rollout design with 18 pediatric primary care clinics in the South Florida area.
Gender:
ALL
Ages:
Between 12 years and 16 years
Trial Updated:
08/12/2024
Locations: Jessie Trice Community Health Center, Miami, Florida +16 locations
Conditions: Depression, Anxiety, Suicide, Drug Use