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All Clinical Trials
A listing of 23125 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
25 - 36 of 23125
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Investigational Combined COVID-19 and Influenza Vaccine
Recruiting
This study aims to evaluate the safety, immune response, and tolerability of an investigational vaccine designed to protect against both COVID-19 and seasonal influenza in adults aged 18 to 64 years. Participants will be randomly assigned to receive the investigational vaccine or a currently available vaccine. The study involves a single vaccination followed by monitoring over several months. Should you express interest, the research site will contact you directly to provide further details and address any questions you may have about study requirements, risks/benefits, and compensation.
Conditions:
Interested in vaccine studies
All Conditions
Healthy
Preventative Trials
Featured Trial
Investigational Stomach Flu Vaccine
Recruiting
The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Interested in vaccine studies
All Conditions
Preventative Trials
Healthy
Age 60+
Featured Trial
Healthy Volunteer Oral COVID-19 Preventative Drug
Recruiting
The main objectives of this study are to assess the safety, effectiveness, and immune response of an investigational oral preventative drug (oral vaccination) in preventing COVID-19 and its symptoms. Participants will be randomly assigned to receive the investigational oral vaccine or a currently available market COVID-19 vaccine. Should you express interest, you will be contacted directly by the research site, who will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Preventative Trials
Healthy
All Conditions
Interested in vaccine studies
Healthy Volunteers
Featured Trial
Kids and Teens Migraine Clinical Study
Recruiting
We are looking for adolescents who experience migraines to take part in a clinical trial. No health insurance is required. The study medicine and any trial-related procedures will be provided.
Conditions:
Migraine
Migraine Disorders
Migraine Headache
Chronic Migraine
Migraine Without Aura
Featured Trial
Type 2 Diabetes Clinical Trial
Recruiting
Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.
Conditions:
Type 2 Diabetes
Diabetes Mellitus Type 2 in Obese
Diabetes Type Two
Type 2 Diabetes Mellitus
Diabete Type 2
Safety and Feasibility of a Machine-Learning Bolus Priming Added to Existing Control Algorithm
Recruiting
A randomized crossover trial assessing glycemic control using Reinforcement Learning trained Bolus Priming System (BPS_RL) added to the the Automated Insulin Delivery as Adaptive NETwork (AIDANET algorithm) compared to the original AIDANET algorithm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: University of Virginia Center for Diabetes Technology, Charlottesville, Virginia
Conditions: Type 1 Diabetes
Investigating the Cholinergic Contribution to Gait Dysfunction in Parkinson's Disease
Recruiting
People with Parkinson's disease often experience problems with 'gait' and balance. Gait refers to the way a person moves while walking, such as their speed and length of steps. People with Parkinson's may experience slowness of movement, shuffle their feet, or have periods of 'freezing', during which their feet feel like they are stuck to the floor. Some people may struggle to maintain their balance and fall. These symptoms are frequently disabling and can lead to a worse quality of life. The ne... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
03/25/2025
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Parkinson Disease
Assessment of Neurodevelopmental Needs in Duchenne Muscular Dystrophy
Recruiting
Duchenne Muscular Dystrophy is a genetic disease that causes progressive muscle weakness. There is now substantial evidence that boys with this disease do not demonstrate age-related gains in their cognitive skills.
The goals of this study are (i) to use a technology-enabled neurobehavioral assessment called National Institutes of Health Toolbox Cognition Battery (NIHTB-CB) to assess brain development over time; (ii) engage with key-stakeholders to understand how neurodevelopmental problems lik... Read More
Gender:
ALL
Ages:
3 years and above
Trial Updated:
03/25/2025
Locations: Children's Hospital of Richmond, Richmond, Virginia
Conditions: Duchenne Muscular Dystrophy
Young Adult Eating Habits
Recruiting
Most individuals with obesity become so before age 35 and adolescent's unhealthy dietary patterns, specifically high intake of ultra-processed foods and poor overall diet quality, may contribute to energy overconsumption and weight gain. The overall objective of this research is to establish proof-of-concept for altered reward processing measured by brain response to ultra-processed foods, an increase in ad libitum energy intake, and adverse effects on executive function in response to an ultra-... Read More
Gender:
ALL
Ages:
Between 18 years and 25 years
Trial Updated:
03/24/2025
Locations: Virginia Polytechnic Institute and State University, Blacksburg, Virginia +1 locations
Conditions: Eating Behavior, Eating Habit
Organic Compounds and Postoperative Delirum
Recruiting
This study involves collecting exhaled breath containing hundreds of volatile organic compounds (VOCs) that are present in very low quantity (parts per billion). VOCs in the exhaled gase carry information to indicate individual's risk for Postoperative Delirium and its severity. Our long-term objectives are to identify breathomic patterns for prediction, early detection, and stratification of POD during pre- and post-operative phases.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
03/24/2025
Locations: University of Virginia Medical Center, Charlottesville, Virginia
Conditions: Identify Postoperative Delirium Using Exhaled Gas Patterns
Effect of Dapagliflozin on Microvascular Function in Women with Symptoms of Coronary Artery Disease
Recruiting
The goal of this clinical trial is to test the effects of a drug (in the drug class called sodium-glucose cotransporter 2 inhibitors) in women who have symptoms of ischemic heart disease. The main questions the study aims to answer are:
Does blood flow in the heart improve with study drug?
Participants will be randomly assigned to a 12-week course of the study drug, dapagliflozin 10mg, or placebo. Blood flow in the heart will be assessed using stress cardiac magnetic resonance imaging at basel... Read More
Gender:
FEMALE
Ages:
Between 18 years and 99 years
Trial Updated:
03/24/2025
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Myocardial Ischemia
Tracking a Tactile Signal Along the Nervous System
Recruiting
Quantify the flow of a tactile signal from the stimulus at the finger at the peripheral nervous system (PNS), to the central nervous system (CNS), and to cognitive perception at the brain in young adults (Aim 1) and individuals with and without stroke (Aim 2).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: Virginia Tech, Roanoke, Virginia
Conditions: Stroke, Tactile Perception
Gut Microbiome and Blood Indices in Patients with AD and Their Spousal Caregivers
Recruiting
Spousal caregivers of Alzheimer's Dementia (AD) patients have an elevated risk of developing AD in the future. Past studies have shown the presence of serum indicators correlated with gut biome dysfunction in AD patients. We hypothesize that the same gut biome dysfunction may be present in spousal caregivers of AD patients.
Gender:
ALL
Ages:
Between 65 years and 90 years
Trial Updated:
03/24/2025
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Alzheimer Disease, Gut Biome
Magnesium and Riboflavin Treatment for Post-Concussion Headache
Recruiting
This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion. The participant will be randomized to either active magnesium and riboflavin capsules or placebo (inert) capsules. The capsules will be taken once a day for 14 days. The participant will also complete a short diary form for the 14 days and will have 3 follow up visits either by telephone or in person.
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
03/24/2025
Locations: University of Virginia Student Health and Wellness Center, Charlottesville, Virginia
Conditions: Concussion, Intermediate
Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain
Recruiting
This proposed pilot study will investigate the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/24/2025
Locations: University of Virginia UVA Health, University Hospital, Charlottesville, Virginia
Conditions: Cancer of Head and Neck, Pain, Face, Pain, Neck
Clinical Validation of a Predictive Test for Postpartum Depression
Recruiting
The goal of this observational study is to develop a blood test that may be predictive of postpartum depression. This Blood test is investigational and not yet FDA approved. Participants will not receive the results of this blood test.
Up to 500 pregnant women will be recruited for the study from 2 sites. Participants must be age 18 or above with a singleton pregnancy and able to provide written consent in English.
The Objective of this Clinical Trial is to prospectively validate the Enlighten... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Postpartum Depression (PPD), Pregnancy
Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes
Recruiting
Animal and observational research in humans suggest that specific types of non-nutritive sweeteners (NNS) may impair glycemic control. However, whether NNS consumption impacts glucose homeostasis in middle-aged/older adults with prediabetes is unknown, and potential mechanisms by which this could occur have yet to be identified. The overall objective of this R21 proposal is to establish proof-of-concept for alterations in glucose homeostasis following intake of sucralose, but not aspartame, in m... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
03/21/2025
Locations: Virginia Tech, Blacksburg, Virginia
Conditions: Continuous Glucose Monitoring, Oral Glucose Tolerance, Insulin Sensitivity, Inflammatory Markers
25 - 36 of 23125