The state of Alabama currently has 2 active clinical trials seeking participants for Resistant Hypertension research studies. These trials are conducted in various cities, including Birmingham, Mobile, Huntsville and Anniston.
A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension
NCT06034743
Recruiting
This is a Phase III, multicentre, randomised, double-blinded, placebo-controlled, parallel group study to evaluate the safety, tolerability and effect of 1 or 2 mg baxdrostat versus placebo, administered once daily (QD) orally, on the reduction of systolic blood pressure in approximately 720 participants aged ≥ 18 years with hypertension, despite a stable regimen of 2 antihypertensive agents at baseline, one of which is a diuretic (uncontrolled hypertension); or ≥ 3 antihypertensive agents at ba... Read More
Gender:
All
Ages:
Between 18 years and 130 years
Trial Updated:
05/27/2024
Locations: Research Site, Birmingham, Alabama +2 locations
Conditions: Uncontrolled Hypertension, Resistant Hypertension
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Allopurinol Improves Heart Function in African Americans With Resistant Hypertension
NCT05888233
Recruiting
African American adults in the United States have the highest prevalence rate of high blood pressure (hypertension) and heart failure in the world. African Americans with treatment resistant hypertension have higher levels of the enzyme - xanthine oxidase compared to Caucasians. This trial will test if administration of the xanthine oxidase inhibitor - Allopurinol (commonly used in the treatment of gout), given over a period of 8 weeks, will improve heart function, exercise ability and quality o... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
08/17/2023
Locations: Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama
Conditions: Heart Failure Preserved Ejection Fraction, Resistant Hypertension
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