There are currently 123 clinical trials in Mobile, Alabama looking for participants to engage in research studies. Trials are conducted at various facilities, including University of South Alabama Mitchell Cancer Institute, MBCCOP - Gulf Coast, Mobile Infirmary Medical Center and University of South Alabama. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Comparing High-Dose Cisplatin Every Three Weeks to Low-Dose Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer
NCT05050162
Recruiting
This phase II/III trial compares the effect of the combination of high-dose cisplatin every three weeks and radiation therapy versus low-dose cisplatin weekly and radiation therapy for the treatment of patients with locoregionally advanced head and neck cancer. Chemotherapy drugs, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays to... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Mobile Infirmary Medical Center, Mobile, Alabama
Conditions: Advanced Head and Neck Squamous Cell Carcinoma, Advanced Hypopharyngeal Squamous Cell Carcinoma, Advanced Laryngeal Squamous Cell Carcinoma, Advanced Oropharyngeal Squamous Cell Carcinoma, Squamous Cell Carcinoma of Unknown Primary
Register for Updates
Device Global Registry for the IlluminOss Bone Stabilization System
NCT05206981
Recruiting
This is a multi-center, observational patient registry. The primary objective of the study is to collect safety and performance data on the IlluminOss Device when used to provide stabilization and alignment for the treatment of traumatic or impending and pathologic fractures.
Gender:
All
Ages:
50 years and above
Trial Updated:
01/23/2024
Locations: Gulf Orthopedics, Mobile, Alabama
Conditions: Traumatic Fracture, Pathological Fracture
Register for Updates
Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry
NCT05880537
Recruiting
Post market registry to assess the safety and efficacy of a novel decellularized human femoral artery allograft (Nexeon AVX Decellularized Femoral Artery,
Gender:
All
Ages:
18 years and above
Trial Updated:
01/23/2024
Locations: Infirmary Heath, Mobile, Alabama
Conditions: End-Stage Renal Disease
Register for Updates
Pelvic Fixation and Fusion During Multilevel Spinal Surgery
NCT05640908
Recruiting
PAULA aims to collect data on the safety, performance, and effectiveness of iFuse Bedrock Granite (GRANITE) in patients who have spinal fusion surgery with pelvic fixation/ fusion.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/16/2024
Locations: USA Neurosurgery, Mobile, Alabama
Conditions: Spinal Fusion, Deformity of Spine
Register for Updates
NICU Antibiotics and Outcomes Trial
NCT03997266
Recruiting
The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELBW) infants in the first days of life. In this 802-subject multicenter placebo-controlled randomized clinical trial, the hypothesis to be tested is that the incidence of adverse outcomes is higher in babies receiving empiric antibiotics (EA) in the first week of life compared to babies receiving placebo. The study targets a population of E... Read More
Gender:
All
Ages:
4 hours and below
Trial Updated:
01/12/2024
Locations: USA Children's and Women's Hospital, Mobile, Alabama
Conditions: Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal
Register for Updates
Protective Effect of Nicotinamide Riboside Against Acetaminophen Toxicity
NCT06214468
Recruiting
Over-the-counter drugs like acetaminophen (e.g., Tylenol®) can be detrimental. In space, astronauts who have pain and constant discomfort use acetaminophen extensively. Investigators are studying the effects of acetaminophen under space-like conditions since acetaminophen might affect astronauts' health. Investigators also wish to see whether a dietary supplement can reduce some negative effects of acetaminophen. It is believed that acetaminophen promotes the productions of chemicals in the bod... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/09/2024
Locations: University of South Alabama, Mobile, Alabama
Conditions: Drug Toxicity
Register for Updates
HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis
NCT04094818
Recruiting
This study will analyze gene expression and other laboratory data from biological samples collected from participants with suspected respiratory, urinary, intra-abdominal, and/or skin & soft tissue infections; or suspected sepsis of any cause.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/21/2023
Locations: University of South Alabama, Mobile, Alabama
Conditions: Respiratory Tract Infections, Urinary Tract Infections, Intra-Abdominal Infections, Skin and Soft Tissue Infection, Sepsis, Suspected Meningitis/Encephalitis or Any Other Infection
Register for Updates
MitraClip REPAIR MR Study
NCT04198870
Recruiting
The objective of this randomized controlled trial (RCT) is to compare the clinical outcome of MitraClip™ device versus surgical repair in patients with severe primary MR who are at moderate surgical risk and whose mitral valve has been determined to be suitable for correction by MV repair surgery by the cardiac surgeon on the local site heart team.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/14/2023
Locations: Cardiology Associates of Mobile, Inc., Mobile, Alabama
Conditions: Mitral Valve Regurgitation
Register for Updates
Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy
NCT04113382
Recruiting
Bowel preparation for pediatric colonoscopy.
Gender:
All
Ages:
Between 2 years and 8 years
Trial Updated:
12/13/2023
Locations: Ferring Investigational Site, Mobile, Alabama
Conditions: Bowel Preparation
Register for Updates
Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone?
NCT05243563
Recruiting
This study will compare the effects of fractionated CO2 laser plus topical steroids versus topical steroids alone in treatment of lichen sclerosus.
Gender:
Female
Ages:
Between 18 years and 85 years
Trial Updated:
12/06/2023
Locations: USA Health Children's and Women's Hospital, Mobile, Alabama +1 locations
Conditions: Vulvar Lichen Sclerosus
Register for Updates
Understanding the Long-term Impact of COVID-19 in Adults (RECOVER)
NCT05172024
Recruiting
This is a combined retrospective and prospective, longitudinal, observational meta-cohort of individuals who will enter the cohort with and without SARS-CoV-2 infection and at varying stages before and after infection. Individuals with and without SARS-CoV-2 infection and with or without Post-Acute Sequelae of COVID-19 (PASC) symptoms will be followed to identify risk factors and occurrence of PASC. This study will be conducted in the United States and subjects will be recruited through inpatien... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/24/2023
Locations: University of South Alabama, Mobile, Alabama
Conditions: SARS-CoV2 Infection
Register for Updates
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
NCT03860883
Recruiting
Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in margins is expected to improve patient quality of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: University of South Alabama Mitchell Cancer Institute, Mobile, Alabama
Conditions: Cutaneous Melanoma, Stage II
Register for Updates