There are currently 10 active clinical trials seeking participants for Macular Degeneration research studies. The states with the highest number of trials for Macular Degeneration participants are California, Texas, Florida and Arizona.
A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
NCT05839041
Recruiting
Investigate the Safety, Pharmacokinetics, and Treatment effects of Single and Multi-dose of Intravitreal AVD-104 in participants with geographic atrophy secondary to age-related macular degeneration.
Gender:
All
Ages:
Between 55 years and 90 years
Trial Updated:
06/13/2024
Locations: Associated Retina Consultants, Gilbert, Arizona +55 locations
Conditions: Geographic Atrophy of the Macula, Macular Degeneration
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Study of Zifibancimig in Participants With Neovascular Age-Related Macular Degeneration
NCT04567303
Recruiting
This is a first in-human study to investigate the safety, tolerability and efficacy of zifibancimig administered through intravitreal (IVT) injections and via the Port Delivery (PD) implant in participants with neovascular age-related macular degeneration (nAMD)
Gender:
All
Ages:
50 years and above
Trial Updated:
06/05/2024
Locations: Barnet Dulaney Perkins Eye Center, Mesa, Arizona +19 locations
Conditions: Macular Degeneration
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Stem Cell Ophthalmology Treatment Study II
NCT03011541
Recruiting
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/12/2024
Locations: MD Stem Cells, Westport, Connecticut +2 locations
Conditions: Retinal Disease, Age-Related Macular Degeneration, Retinitis Pigmentosa, Stargardt Disease, Optic Neuropathy, Nonarteritic Ischemic Optic Neuropathy, Optic Atrophy, Optic Nerve Disease, Glaucoma, Leber Hereditary Optic Neuropathy, Blindness, Vision Loss Night, Vision Loss Partial, Vision, Low, Retinopathy, Maculopathy, Macular Degeneration, Retina Atrophy
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Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study
NCT05797896
Recruiting
An observational study to investigate the natural history and evaluate biomarkers of participants with geographic atrophy secondary to age-related macular degeneration
Gender:
All
Ages:
65 years and above
Trial Updated:
04/08/2024
Locations: Global Research Management, Glendale, California +21 locations
Conditions: Dry Age-related Macular Degeneration, Geographic Atrophy, Retinal Disease, Macular Degeneration, Macular Atrophy, Retinal Degeneration, Eye Diseases
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NYSCF Scientific Discovery Biobank
NCT06203106
Recruiting
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate diverse disease research using cells from the body (such as skin or blood cells) to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and store the samples for future use. Through this research, researchers hope to identify future treatments or even cures for the major diseases of our time.
Gender:
All
Ages:
30 days and above
Trial Updated:
03/21/2024
Locations: New York Stem Cell Foundation Research Institute, New York, New York
Conditions: ALS, Amyotrophic Lateral Sclerosis, Alzheimer Disease, Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset, Batten Disease, Corticobasal Degeneration, Dementia, Frontotemporal Dementia, Huntington Disease, Lewy Body Disease, Multiple Sclerosis, Multiple System Atrophy, Parkinson Disease, Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy, INAD, Diabetes, Diabetes Mellitus, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Macular Degeneration, Ovarian Cancer, Cervical Cancer, Uterine Cancer, Vaginal Cancer, Vulvar Cancer, PTSD, Post Traumatic Stress Disorder
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Factors in Learning And Plasticity: Healthy Vision
NCT05439759
Recruiting
A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the National Eye Institute (NEI) to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the National Institute of M... Read More
Gender:
All
Ages:
Between 18 years and 30 years
Trial Updated:
02/21/2024
Locations: UAB, Birmingham, Alabama +1 locations
Conditions: Central Visual Impairment, Macular Degeneration
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Factors in Learning And Plasticity: Macular Degeneration
NCT05454124
Recruiting
A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the NEI to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the NIMH RDOC framework and studies in an aging popu... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
02/21/2024
Locations: UAB, Birmingham, Alabama
Conditions: Central Visual Impairment, Macular Degeneration
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Scotoma Perimetry Oculomotor Training
NCT05456581
Recruiting
The proposed research is relevant to public health because a greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the NEI to support research on visual disorders, mechanisms of visual function and preservation of sight. Declines in vision are particularly common in older adults and thus in... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
01/24/2024
Locations: UAB, Birmingham, Alabama
Conditions: Macular Degeneration, Central Visual Impairment
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Pistachios and Neural Macular Pigment
NCT05283941
Recruiting
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss as people age. Studies have shown that lutein and zeaxanthin, nutrients found in green leafy vegetables and egg yolks, can help protect against AMD in older adults. These nutrients form a pigment in the retina (macular pigment) that can help protect the retina from light damage. Pistachios are rich sources of both lutein and zeaxanthin; thus, dietary intake of pistachios could serve as a beneficial food sourc... Read More
Gender:
All
Ages:
Between 40 years and 70 years
Trial Updated:
03/07/2023
Locations: Clinical and Translational Research Center (CTRC) - Tufts, Boston, Massachusetts
Conditions: Macular Degeneration, Retinal Degeneration, Retinal Diseases, Eye Diseases
Register for Updates
Comparing Vision Tests in a Virtual Reality Headset to Existing Analogues
NCT04714424
Recruiting
The purpose of this study is to compare the results of vision tests that are algorithmically derived and delivered through a virtual reality headset with those delivered through the existing technology standards (eg. Humphrey for field tests). Tests that the researchers will be conducting include vision field perimetry, Amsler, acuity chart, contrast- sensitivity and currently used office tests.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/22/2022
Locations: New York Eye & Ear Infirmary of Mount Sinai, New York, New York
Conditions: Ptosis, Macular Degeneration, Ametropia
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