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Atrial Fibrillation Clinical Trials in Canada
A listing of 26 Atrial Fibrillation clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
13 - 24 of 26
There are currently 26 active clinical trials seeking participants for Atrial Fibrillation research studies. The states with the highest number of trials for Atrial Fibrillation participants are .
Surgical Ablation of AF Efficacy Trial
Recruiting
SAFE is an international multicentre RCT of concomitant surgical atrial fibrillation (AF) ablation in patients with paroxysmal or persistent AF undergoing cardiac surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: Hamilton General Hospital, Hamilton, Ontario
Conditions: Atrial Fibrillation, Heart Failure
Amplatzer Amulet LAAO Vs. NOAC
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy.
The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: University Hospital - Univ. of Alabama at Birmingham (UAB), Birmingham, Alabama +131 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
Recruiting
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery.
All patients with a qualifying POAF event, who decline randomization, will be offered the option of enrollment in a parallel registry that captures their ba... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: CHI St. Vincent, Arkansas, Little Rock, Arkansas +95 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
Reversal of Atrial Substrate to Prevent Atrial
Recruiting
A multi-center, randomized trial to examine the effect of aggressive risk factor control and arrhythmia trigger-based intervention on recurrence of atrial fibrillation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/13/2024
Locations: Foothills Hospital, Calgary, Alberta +16 locations
Conditions: Atrial Fibrillation
DETECTion of PeriOperative Atrial Fibrillation After Noncardiac Surgery
Recruiting
This is a multicentre prospective cohort study where patients will receive up to 14 days of continuous ECG monitoring by wearing a portable monitoring device, starting within 72 hours after noncardiac surgery.
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
11/05/2024
Locations: Hamilton General Hospital, Hamilton, Ontario +5 locations
Conditions: Atrial Fibrillation, Atrial Flutter
Early Atrial Fibrillation Ablation for Stroke Prevention in Patients with High Comorbidity Burden (EASThigh-AFNET 11)
Recruiting
EASThigh-AFNET 11 is an international, prospective, randomized, open, blinded endpoint assessment, multicenter trial (Treatment Strategy trial).
The objective of EASThigh-AFNET 11 is to investigate whether early atrial fibrillation ablation in patients with atrial fibrillation (AF) and a high comorbidity burden (CHA2DS2-VASc ≥4) reduces cardiovascular events (stroke, cardiovascular death, or heart failure events) compared to usual care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: Several sites, Multiple Locations, Not set +4 locations
Conditions: Atrial Fibrillation
Oral Amiodarone for Acute Cardioversion of Atrial Fibrillation Study
Recruiting
The investigators will seek to determine the safety and efficacy of high-dose amiodarone (2000mg), given as a single uniform oral dose, for the treatment of acute atrial fibrillation in both a hospital inpatient and ambulatory outpatient setting. The investigators will conduct a placebo-controlled randomized trial, with outcome ascertainment at 48h.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/15/2024
Locations: University of Calgary, Calgary, Alberta
Conditions: Atrial Fibrillation
QOL Improvement After Cardioversion of Persistent AF (QOL-CAFRCT)
Recruiting
Atrial fibrillation (AF) is a type of irregular heart rhythm due to electrical signal disturbances of the heart. It is a very common arrhythmia and the risk of developing AF increases with age and with other risk factors such as diabetes, high blood pressure, and underlying heart disease. The main complications of AF are heart failure and stroke. However, studies have shown that restoration of normal rhythm does not reduce these complications. Rather, these complications are mitigated by control... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: University of Ottawa Heart Institute, Ottawa, Ontario
Conditions: Atrial Fibrillation
Characterization of Arrhythmia Substrate to Ablate Persistent Atrial Fibrillation
Recruiting
A multicentre, parallel group, two arm, single-blinded randomized clinical trial, assessing the efficacy of a patient-tailored catheter ablation (CA) strategy guided by atrial scar mapping in addition to pulmonary vein isolation (PVI) when compared to PVI alone in patients with persistent atrial fibrillation (AF).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: Libin Cardiovascular Institute, Calgary, Alberta +14 locations
Conditions: Atrial Fibrillation
Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation
Recruiting
The main purpose of this project is to evaluate the effects of high-intensity interval training (HIIT) compared to moderate-intensity continuous exercise training (MICE) and standard care on exercise capacity and quality of life in patients with persistent or permanent atrial fibrillation. Positive findings are vitally important for these patients, given the condition's substantial morbidity, mortality and high economic costs.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
05/06/2024
Locations: London Health Sciences Network, London, Ontario +1 locations
Conditions: Atrial Fibrillation
A Behavioural Weight Loss Intervention Delivered in Cardiac Rehabilitation for Patients With Atrial Fibrillation and Obesity
Recruiting
One-in-four Canadians will be diagnosed with an abnormal heart rhythm called atrial fibrillation (AF) in their lifetime. This is expected to double by 2050, owing to an aging population and increased age- and health behaviour-associated AF risk factors (e.g., poor cardiorespiratory fitness, Type II diabetes, hypertension, and obesity). AF is associated with an increased risk of severe health outcomes including stroke, heart failure, dementia, and death. Nearly three-quarters of people with AF al... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Behavioural Medicine Lab, Calgary, Alberta
Conditions: Atrial Fibrillation, Obesity
Pulsed Field Ablation and Pulsed Field CRyoAbLation in PErsistent AtriaL FibrilLation
Recruiting
A prospective, two-arm, multi-center, randomized, open-label, pre-market, First-in-Human clinical study designed to provide safety and performance data regarding the use of the Adagio PFA and PFCA Systems in the treatment of PsAF.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/23/2024
Locations: Onze-Lieve-Vrouwziekenhuis (OLV), Aalst, Not set +5 locations
Conditions: Atrial Fibrillation
13 - 24 of 26