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All Clinical Trials in Canada
A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
Recruiting
This phase III trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with newly diagnosed or previously untreated low-grade glioma (LGG) that does not have a genetic abnormality called BRAFV600E mutation and is not associated with systemic neurofibromatosis type 1. Selumetinib works by blocking some of the enzymes needed for cell growth and may kill tumor cells. Carboplatin and vincristine are chemotherapy drugs... Read More
This phase III trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with newly diagnosed or previously untreated low-grade glioma (LGG) that does not have a genetic abnormality called BRAFV600E mutation and is not associated with systemic neurofibromatosis type 1. Selumetinib works by blocking some of the enzymes needed for cell growth and may kill tumor cells. Carboplatin and vincristine are chemotherapy drugs that work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. The overall goal of this study is to see if selumetinib works just as well as the standard treatment of CV for patients with LGG. Another goal of this study is to compare the effects of selumetinib versus CV in subjects with LGG to find out which is better. Additionally, this trial will also examine if treatment with selumetinib improves the quality of life for subjects who take it. Read Less
Gender:
ALL
Ages:
Between 2 years and 21 years
Trial Updated:
08/22/2025
Locations: Children's Hospital of Alabama, Birmingham, Alabama +131 locations
Children's Hospital of Alabama, Birmingham, Alabama
Banner Children's at Desert, Mesa, Arizona
Phoenix Childrens Hospital, Phoenix, Arizona
Arkansas Children's Hospital, Little Rock, Arkansas
Loma Linda University Medical Center, Loma Linda, California
Miller Children's and Women's Hospital Long Beach, Long Beach, California
Children's Hospital Los Angeles, Los Angeles, California
Cedars Sinai Medical Center, Los Angeles, California
Mattel Children's Hospital UCLA, Los Angeles, California
Kaiser Permanente-Oakland, Oakland, California
Children's Hospital of Orange County, Orange, California
Lucile Packard Children's Hospital Stanford University, Palo Alto, California
Rady Children's Hospital - San Diego, San Diego, California
UCSF Medical Center-Mission Bay, San Francisco, California
Children's Hospital Colorado, Aurora, Colorado
Connecticut Children's Medical Center, Hartford, Connecticut
Yale University, New Haven, Connecticut
Alfred I duPont Hospital for Children, Wilmington, Delaware
Children's National Medical Center, Washington, District of Columbia
Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida
University of Florida Health Science Center - Gainesville, Gainesville, Florida
Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida
Nemours Children's Clinic-Jacksonville, Jacksonville, Florida
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
Nicklaus Children's Hospital, Miami, Florida
AdventHealth Orlando, Orlando, Florida
Arnold Palmer Hospital for Children, Orlando, Florida
Nemours Children's Hospital, Orlando, Florida
Nemours Children's Clinic - Pensacola, Pensacola, Florida
Sacred Heart Hospital, Pensacola, Florida
Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida
Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii
Saint Luke's Cancer Institute - Boise, Boise, Idaho
Lurie Children's Hospital-Chicago, Chicago, Illinois
University of Illinois, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Saint Jude Midwest Affiliate, Peoria, Illinois
Southern Illinois University School of Medicine, Springfield, Illinois
Riley Hospital for Children, Indianapolis, Indiana
Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana
Blank Children's Hospital, Des Moines, Iowa
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
Norton Children's Hospital, Louisville, Kentucky
Children's Hospital New Orleans, New Orleans, Louisiana
Eastern Maine Medical Center, Bangor, Maine
Maine Children's Cancer Program, Scarborough, Maine
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
Walter Reed National Military Medical Center, Bethesda, Maryland
Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Dana-Farber Cancer Institute, Boston, Massachusetts
C S Mott Children's Hospital, Ann Arbor, Michigan
Children's Hospital of Michigan, Detroit, Michigan
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan
Corewell Health Children's, Royal Oak, Michigan
Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota
University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota
Mayo Clinic in Rochester, Rochester, Minnesota
University of Mississippi Medical Center, Jackson, Mississippi
Children's Mercy Hospitals and Clinics, Kansas City, Missouri
Cardinal Glennon Children's Medical Center, Saint Louis, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Children's Hospital and Medical Center of Omaha, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
Morristown Medical Center, Morristown, New Jersey
Albany Medical Center, Albany, New York
Roswell Park Cancer Institute, Buffalo, New York
NYU Langone Hospital - Long Island, Mineola, New York
The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York
Memorial Sloan Kettering Cancer Center, New York, New York
University of Rochester, Rochester, New York
State University of New York Upstate Medical University, Syracuse, New York
New York Medical College, Valhalla, New York
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina
Duke University Medical Center, Durham, North Carolina
East Carolina University, Greenville, North Carolina
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Sanford Broadway Medical Center, Fargo, North Dakota
Children's Hospital Medical Center of Akron, Akron, Ohio
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Rainbow Babies and Childrens Hospital, Cleveland, Ohio
Nationwide Children's Hospital, Columbus, Ohio
Dayton Children's Hospital, Dayton, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Oregon Health and Science University, Portland, Oregon
Geisinger Medical Center, Danville, Pennsylvania
Penn State Children's Hospital, Hershey, Pennsylvania
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania
Rhode Island Hospital, Providence, Rhode Island
Medical University of South Carolina, Charleston, South Carolina
Prisma Health Richland Hospital, Columbia, South Carolina
BI-LO Charities Children's Cancer Center, Greenville, South Carolina
East Tennessee Childrens Hospital, Knoxville, Tennessee
Saint Jude Children's Research Hospital, Memphis, Tennessee
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee
Dell Children's Medical Center of Central Texas, Austin, Texas
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
El Paso Children's Hospital, El Paso, Texas
Cook Children's Medical Center, Fort Worth, Texas
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas
M D Anderson Cancer Center, Houston, Texas
Covenant Children's Hospital, Lubbock, Texas
UMC Cancer Center / UMC Health System, Lubbock, Texas
Children's Hospital of San Antonio, San Antonio, Texas
Methodist Children's Hospital of South Texas, San Antonio, Texas
University of Texas Health Science Center at San Antonio, San Antonio, Texas
Primary Children's Hospital, Salt Lake City, Utah
University of Vermont and State Agricultural College, Burlington, Vermont
Children's Hospital of The King's Daughters, Norfolk, Virginia
VCU Massey Comprehensive Cancer Center, Richmond, Virginia
Carilion Children's, Roanoke, Virginia
Seattle Children's Hospital, Seattle, Washington
Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington
Mary Bridge Children's Hospital and Health Center, Tacoma, Washington
Madigan Army Medical Center, Tacoma, Washington
West Virginia University Healthcare, Morgantown, West Virginia
University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin
Children's Hospital of Wisconsin, Milwaukee, Wisconsin
British Columbia Children's Hospital, Vancouver, British Columbia
Janeway Child Health Centre, Saint John's, Newfoundland and Labrador
IWK Health Centre, Halifax, Nova Scotia
The Montreal Children's Hospital of the MUHC, Montreal, Quebec
Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec
CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set
HIMA San Pablo Oncologic Hospital, Caguas, Not set
Conditions: Low Grade Glioma, Low Grade Astrocytoma, Metastatic Low Grade Astrocytoma, Metastatic Low Grade Glioma
Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
Recruiting
This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with high risk acute myeloid leukemia (AML): 1) daunorubicin and cytarabine liposome alone; 2) cytarabine and daunorubicin with venetoclax; 3) azacitidine and venetoclax; 4) daunorubicin and cytarabine liposome and venetoclax. "High-risk" refers to traits that have been known to make the AML harder to t... Read More
This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with high risk acute myeloid leukemia (AML): 1) daunorubicin and cytarabine liposome alone; 2) cytarabine and daunorubicin with venetoclax; 3) azacitidine and venetoclax; 4) daunorubicin and cytarabine liposome and venetoclax. "High-risk" refers to traits that have been known to make the AML harder to treat. Cytarabine is in a class of medications called antimetabolites. It works by slowing or stopping the growth of cancer cells in the body. Daunorubicin is in a class of medications called anthracyclines. It also works by slowing or stopping the growth of cancer cells in the body. Azacitidine is in a class of medications called demethylation agents. It works by helping the bone marrow to produce normal blood cells and by killing abnormal cells. Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. There is evidence that these newer experimental treatment regimens may work better in getting rid of more AML compared to the standard approach of cytarabine and daunorubicin. Read Less
Gender:
ALL
Ages:
Between 18 years and 59 years
Trial Updated:
08/22/2025
Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +182 locations
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama
Mayo Clinic Hospital in Arizona, Phoenix, Arizona
Banner University Medical Center - Tucson, Tucson, Arizona
University of Arizona Cancer Center-North Campus, Tucson, Arizona
University of Arkansas for Medical Sciences, Little Rock, Arkansas
Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California
Cedars Sinai Medical Center, Los Angeles, California
University of California Davis Comprehensive Cancer Center, Sacramento, California
UCSF Medical Center-Parnassus, San Francisco, California
Mills Health Center, San Mateo, California
Yale University, New Haven, Connecticut
Mayo Clinic in Florida, Jacksonville, Florida
Augusta University Medical Center, Augusta, Georgia
Hawaii Cancer Care - Westridge, 'Aiea, Hawaii
Pali Momi Medical Center, 'Aiea, Hawaii
Hawaii Cancer Care Inc - Waterfront Plaza, Honolulu, Hawaii
Straub Clinic and Hospital, Honolulu, Hawaii
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii
Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho
Saint Luke's Cancer Institute - Boise, Boise, Idaho
Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho
Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho
Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho
Saint Luke's Cancer Institute - Meridian, Meridian, Idaho
Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho
Saint Luke's Cancer Institute - Nampa, Nampa, Idaho
Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho
Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho
OSF Saint Joseph Medical Center, Bloomington, Illinois
Illinois CancerCare-Bloomington, Bloomington, Illinois
Illinois CancerCare-Canton, Canton, Illinois
Illinois CancerCare-Carthage, Carthage, Illinois
Northwestern University, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Illinois CancerCare-Dixon, Dixon, Illinois
Crossroads Cancer Center, Effingham, Illinois
Illinois CancerCare-Eureka, Eureka, Illinois
NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois
Illinois CancerCare-Galesburg, Galesburg, Illinois
NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois
NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois
Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois
Illinois CancerCare-Macomb, Macomb, Illinois
Loyola University Medical Center, Maywood, Illinois
Cancer Care Center of O'Fallon, O'Fallon, Illinois
Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois
Illinois CancerCare-Pekin, Pekin, Illinois
Illinois CancerCare-Peoria, Peoria, Illinois
Methodist Medical Center of Illinois, Peoria, Illinois
OSF Saint Francis Medical Center, Peoria, Illinois
Illinois CancerCare-Peru, Peru, Illinois
Illinois CancerCare-Princeton, Princeton, Illinois
Southern Illinois University School of Medicine, Springfield, Illinois
Springfield Clinic, Springfield, Illinois
Springfield Memorial Hospital, Springfield, Illinois
Illinois CancerCare - Washington, Washington, Illinois
Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
University of Kansas Clinical Research Center, Fairway, Kansas
University of Kansas Cancer Center, Kansas City, Kansas
University of Kansas Hospital-Indian Creek Campus, Overland Park, Kansas
University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky
UofL Health Medical Center Northeast, Louisville, Kentucky
LSU Health Baton Rouge-North Clinic, Baton Rouge, Louisiana
Our Lady of the Lake Physician Group, Baton Rouge, Louisiana
Our Lady of The Lake, Baton Rouge, Louisiana
MaineHealth Maine Medical Center - Portland, Portland, Maine
MaineHealth Cancer Care and IV Therapy - South Portland, South Portland, Maine
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
Tufts Medical Center, Boston, Massachusetts
Dana-Farber Cancer Institute, Boston, Massachusetts
Lahey Hospital and Medical Center, Burlington, Massachusetts
Lahey Medical Center-Peabody, Peabody, Massachusetts
Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan
Wayne State University/Karmanos Cancer Institute, Detroit, Michigan
Henry Ford Hospital, Detroit, Michigan
Weisberg Cancer Treatment Center, Farmington Hills, Michigan
Cancer Hematology Centers - Flint, Flint, Michigan
Genesee Hematology Oncology PC, Flint, Michigan
Genesys Hurley Cancer Institute, Flint, Michigan
Hurley Medical Center, Flint, Michigan
Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan
Henry Ford Medical Center-Columbus, Novi, Michigan
Henry Ford West Bloomfield Hospital, West Bloomfield, Michigan
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan
Mercy Hospital, Coon Rapids, Minnesota
Essentia Health - Deer River Clinic, Deer River, Minnesota
Essentia Health Cancer Center, Duluth, Minnesota
Essentia Health Hibbing Clinic, Hibbing, Minnesota
Abbott-Northwestern Hospital, Minneapolis, Minnesota
Mayo Clinic in Rochester, Rochester, Minnesota
Regions Hospital, Saint Paul, Minnesota
United Hospital, Saint Paul, Minnesota
Essentia Health Sandstone, Sandstone, Minnesota
Essentia Health Virginia Clinic, Virginia, Minnesota
Baptist Memorial Hospital and Cancer Center-Golden Triangle, Columbus, Mississippi
Baptist Cancer Center-Grenada, Grenada, Mississippi
Baptist Memorial Hospital and Cancer Center-Union County, New Albany, Mississippi
Baptist Memorial Hospital and Cancer Center-Oxford, Oxford, Mississippi
Baptist Memorial Hospital and Cancer Center-Desoto, Southhaven, Mississippi
Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Siteman Cancer Center-South County, Saint Louis, Missouri
Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri
Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri
Community Hospital of Anaconda, Anaconda, Montana
Billings Clinic Cancer Center, Billings, Montana
Bozeman Health Deaconess Hospital, Bozeman, Montana
Benefis Sletten Cancer Institute, Great Falls, Montana
Logan Health Medical Center, Kalispell, Montana
Community Medical Center, Missoula, Montana
Nebraska Medicine-Bellevue, Bellevue, Nebraska
Nebraska Medicine-Village Pointe, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
OptumCare Cancer Care at Seven Hills, Henderson, Nevada
OptumCare Cancer Care at Charleston, Las Vegas, Nevada
OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada
Saint Barnabas Medical Center, Livingston, New Jersey
Monmouth Medical Center, Long Branch, New Jersey
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
The Valley Hospital - Luckow Pavilion, Paramus, New Jersey
Valley Health System Ridgewood Campus, Ridgewood, New Jersey
Community Medical Center, Toms River, New Jersey
University of New Mexico Cancer Center, Albuquerque, New Mexico
Montefiore Medical Center - Moses Campus, Bronx, New York
Roswell Park Cancer Institute, Buffalo, New York
Northwell Health/Center for Advanced Medicine, Lake Success, New York
North Shore University Hospital, Manhasset, New York
Mount Sinai Hospital, New York, New York
University of Rochester, Rochester, New York
State University of New York Upstate Medical University, Syracuse, New York
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina
Duke University Medical Center, Durham, North Carolina
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Ohio State University Comprehensive Cancer Center, Columbus, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon
Providence Portland Medical Center, Portland, Oregon
Providence Saint Vincent Medical Center, Portland, Oregon
Oregon Health and Science University, Portland, Oregon
Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania
Geisinger Medical Center, Danville, Pennsylvania
Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania
University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania
Reading Hospital, West Reading, Pennsylvania
Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina
Prisma Health Cancer Institute - Easley, Easley, South Carolina
Prisma Health Cancer Institute - Butternut, Greenville, South Carolina
Prisma Health Cancer Institute - Faris, Greenville, South Carolina
Prisma Health Cancer Institute - Eastside, Greenville, South Carolina
Prisma Health Cancer Institute - Greer, Greer, South Carolina
Prisma Health Cancer Institute - Seneca, Seneca, South Carolina
Baptist Memorial Hospital and Cancer Center-Collierville, Collierville, Tennessee
University of Tennessee - Knoxville, Knoxville, Tennessee
Baptist Memorial Hospital and Cancer Center-Memphis, Memphis, Tennessee
Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah
University of Vermont Medical Center, Burlington, Vermont
University of Vermont and State Agricultural College, Burlington, Vermont
University of Virginia Cancer Center, Charlottesville, Virginia
Inova Schar Cancer Institute, Fairfax, Virginia
Inova Fairfax Hospital, Falls Church, Virginia
Swedish Cancer Institute-Edmonds, Edmonds, Washington
Swedish Cancer Institute-Issaquah, Issaquah, Washington
Swedish Medical Center-First Hill, Seattle, Washington
ThedaCare Regional Cancer Center, Appleton, Wisconsin
Duluth Clinic Ashland, Ashland, Wisconsin
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin
Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin
Gundersen Lutheran Medical Center, La Crosse, Wisconsin
Medical College of Wisconsin, Milwaukee, Wisconsin
Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta
CancerCare Manitoba, Winnipeg, Manitoba
Centro Comprensivo de Cancer de UPR, San Juan, Not set
San Juan City Hospital, San Juan, Not set
Conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy, Acute Myeloid Leukemia, Myelodysplasia-Related
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)
Recruiting
This phase II MyeloMATCH treatment trial compares cytarabine with daunorubicin versus cytarabine with daunorubicin and venetoclax versus venetoclax with azacitidine for the treatment of younger patients with intermediate risk acute myeloid leukemia (AML). Cytarabine is a drug that inhibits some of the enzymes needed for deoxyribonucleic acid (DNA) replication and repair and can slow or stop the growth of cancer cells. Daunorubicin is a drug that blocks a certain enzyme needed for cell division a... Read More
This phase II MyeloMATCH treatment trial compares cytarabine with daunorubicin versus cytarabine with daunorubicin and venetoclax versus venetoclax with azacitidine for the treatment of younger patients with intermediate risk acute myeloid leukemia (AML). Cytarabine is a drug that inhibits some of the enzymes needed for deoxyribonucleic acid (DNA) replication and repair and can slow or stop the growth of cancer cells. Daunorubicin is a drug that blocks a certain enzyme needed for cell division and DNA repair, and it may kill cancer cells. Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Azacitidine is a drug that interacts with DNA to activate tumor-suppressing genes, resulting in an anti-tumor effect. Adding venetoclax to cytarabine and daunorubicin, and adding venetoclax to azacitidine, may work better than the usual treatment of cytarabine with daunorubicin alone. To decide if they are better, the study doctors are looking to see if venetoclax increases the rate of elimination of AML in participants by 20% or more compared to the usual approach. Read Less
Gender:
ALL
Ages:
Between 18 years and 59 years
Trial Updated:
08/22/2025
Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +151 locations
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama
Banner University Medical Center - Tucson, Tucson, Arizona
University of Arizona Cancer Center-North Campus, Tucson, Arizona
Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California
Cedars Sinai Medical Center, Los Angeles, California
UCSF Medical Center-Parnassus, San Francisco, California
Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho
Saint Luke's Cancer Institute - Boise, Boise, Idaho
Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho
Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho
Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho
Saint Luke's Cancer Institute - Meridian, Meridian, Idaho
Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho
Saint Luke's Cancer Institute - Nampa, Nampa, Idaho
Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho
Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho
Centralia Oncology Clinic, Centralia, Illinois
Northwestern University, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Crossroads Cancer Center, Effingham, Illinois
NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois
NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois
NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois
Loyola University Medical Center, Maywood, Illinois
UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois
Cancer Care Center of O'Fallon, O'Fallon, Illinois
University of Chicago Medicine-Orland Park, Orland Park, Illinois
Southern Illinois University School of Medicine, Springfield, Illinois
Springfield Clinic, Springfield, Illinois
Springfield Memorial Hospital, Springfield, Illinois
UChicago Medicine Northwest Indiana, Crown Point, Indiana
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
University of Kansas Clinical Research Center, Fairway, Kansas
University of Kansas Cancer Center, Kansas City, Kansas
University of Kansas Hospital-Indian Creek Campus, Overland Park, Kansas
University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
LSU Health Baton Rouge-North Clinic, Baton Rouge, Louisiana
Our Lady of the Lake Physician Group, Baton Rouge, Louisiana
Our Lady of The Lake, Baton Rouge, Louisiana
MaineHealth Maine Medical Center - Portland, Portland, Maine
MaineHealth Cancer Care and IV Therapy - South Portland, South Portland, Maine
Tufts Medical Center, Boston, Massachusetts
Lahey Hospital and Medical Center, Burlington, Massachusetts
Lahey Medical Center-Peabody, Peabody, Massachusetts
Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan
Henry Ford Hospital, Detroit, Michigan
Cancer Hematology Centers - Flint, Flint, Michigan
Genesee Hematology Oncology PC, Flint, Michigan
Genesys Hurley Cancer Institute, Flint, Michigan
Hurley Medical Center, Flint, Michigan
Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan
Henry Ford Medical Center-Columbus, Novi, Michigan
Henry Ford West Bloomfield Hospital, West Bloomfield, Michigan
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan
Mercy Hospital, Coon Rapids, Minnesota
Essentia Health - Deer River Clinic, Deer River, Minnesota
Essentia Health Cancer Center, Duluth, Minnesota
Essentia Health Hibbing Clinic, Hibbing, Minnesota
Abbott-Northwestern Hospital, Minneapolis, Minnesota
Regions Hospital, Saint Paul, Minnesota
United Hospital, Saint Paul, Minnesota
Essentia Health Sandstone, Sandstone, Minnesota
Essentia Health Virginia Clinic, Virginia, Minnesota
Baptist Memorial Hospital and Cancer Center-Golden Triangle, Columbus, Mississippi
Baptist Cancer Center-Grenada, Grenada, Mississippi
Baptist Memorial Hospital and Cancer Center-Union County, New Albany, Mississippi
Baptist Memorial Hospital and Cancer Center-Oxford, Oxford, Mississippi
Baptist Memorial Hospital and Cancer Center-Desoto, Southhaven, Mississippi
Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Siteman Cancer Center-South County, Saint Louis, Missouri
Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri
Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri
Community Hospital of Anaconda, Anaconda, Montana
Billings Clinic Cancer Center, Billings, Montana
Bozeman Health Deaconess Hospital, Bozeman, Montana
Benefis Sletten Cancer Institute, Great Falls, Montana
Logan Health Medical Center, Kalispell, Montana
Community Medical Center, Missoula, Montana
Nebraska Medicine-Bellevue, Bellevue, Nebraska
Nebraska Medicine-Village Pointe, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
OptumCare Cancer Care at Seven Hills, Henderson, Nevada
OptumCare Cancer Care at Charleston, Las Vegas, Nevada
OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey
Saint Barnabas Medical Center, Livingston, New Jersey
Monmouth Medical Center, Long Branch, New Jersey
Memorial Sloan Kettering Monmouth, Middletown, New Jersey
Memorial Sloan Kettering Bergen, Montvale, New Jersey
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
The Valley Hospital - Luckow Pavilion, Paramus, New Jersey
Valley Health System Ridgewood Campus, Ridgewood, New Jersey
Community Medical Center, Toms River, New Jersey
University of New Mexico Cancer Center, Albuquerque, New Mexico
Montefiore Medical Center - Moses Campus, Bronx, New York
Roswell Park Cancer Institute, Buffalo, New York
Memorial Sloan Kettering Commack, Commack, New York
Memorial Sloan Kettering Cancer Center, New York, New York
University of Rochester, Rochester, New York
Memorial Sloan Kettering Nassau, Uniondale, New York
Novant Health Presbyterian Medical Center, Charlotte, North Carolina
Duke University Medical Center, Durham, North Carolina
Novant Health Forsyth Medical Center, Winston-Salem, North Carolina
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Case Western Reserve University, Cleveland, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon
Providence Portland Medical Center, Portland, Oregon
Providence Saint Vincent Medical Center, Portland, Oregon
Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania
Geisinger Medical Center, Danville, Pennsylvania
Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania
University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania
Reading Hospital, West Reading, Pennsylvania
Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina
Prisma Health Cancer Institute - Easley, Easley, South Carolina
Prisma Health Cancer Institute - Butternut, Greenville, South Carolina
Prisma Health Cancer Institute - Faris, Greenville, South Carolina
Prisma Health Cancer Institute - Eastside, Greenville, South Carolina
Prisma Health Cancer Institute - Greer, Greer, South Carolina
Prisma Health Cancer Institute - Seneca, Seneca, South Carolina
Baptist Memorial Hospital and Cancer Center-Collierville, Collierville, Tennessee
Baptist Memorial Hospital and Cancer Center-Memphis, Memphis, Tennessee
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas
Ben Taub General Hospital, Houston, Texas
Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah
University of Virginia Cancer Center, Charlottesville, Virginia
Inova Schar Cancer Institute, Fairfax, Virginia
Inova Fairfax Hospital, Falls Church, Virginia
Swedish Cancer Institute-Edmonds, Edmonds, Washington
Swedish Cancer Institute-Issaquah, Issaquah, Washington
Swedish Medical Center-First Hill, Seattle, Washington
Duluth Clinic Ashland, Ashland, Wisconsin
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin
Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin
Gundersen Lutheran Medical Center, La Crosse, Wisconsin
Medical College of Wisconsin, Milwaukee, Wisconsin
Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta
CancerCare Manitoba, Winnipeg, Manitoba
Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario
CSSS Champlain-Charles Le Moyne, Greenfield Park, Quebec
CIUSSSEMTL-Hopital Maisonneuve-Rosemont, Montreal, Quebec
Jewish General Hospital, Montreal, Quebec
Centro Comprensivo de Cancer de UPR, San Juan, Not set
San Juan City Hospital, San Juan, Not set
Conditions: Acute Myeloid Leukemia
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
Recruiting
The main objective of this study is to evaluate the efficacy of satralizumab compared with placebo based on time from randomization to the first occurrence of an adjudicated MOGAD relapse in the double-blind (DB) treatment period. Participants who experience an adjudicated relapse or complete the DB period can enter open-label extension (OLE) period. After the primary clinical cutoff date (CCOD), additional adolescent participants may be enrolled directly into the OLE period.
The main objective of this study is to evaluate the efficacy of satralizumab compared with placebo based on time from randomization to the first occurrence of an adjudicated MOGAD relapse in the double-blind (DB) treatment period. Participants who experience an adjudicated relapse or complete the DB period can enter open-label extension (OLE) period. After the primary clinical cutoff date (CCOD), additional adolescent participants may be enrolled directly into the OLE period. Read Less
Gender:
ALL
Ages:
12 years and above
Trial Updated:
08/22/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +80 locations
University of Alabama at Birmingham, Birmingham, Alabama
Mayo Clinic- Scottsdale, Scottsdale, Arizona
University of California Irvine - Manchester Pavilion, Irvine, California
University of Colorado - Anschutz Medical Campus (University of Colorado Health Sciences Center), Aurora, Colorado
Medstar Georgetown University Hospital, Washington, District of Columbia
University of Florida College of Medicine Gainesville, Gainesville, Florida
Nemours Children's Clinic - of the Nemours Foundation, Jacksonville, Florida
Meridian Clinical Research, LLC, Savannah, Georgia
Northwestern University, Chicago, Illinois
Consultants in Neurology Ltd, Northbrook, Illinois
Johns Hopkins, Baltimore, Maryland
Massachusetts General Hospital, Boston, Massachusetts
Memorial Healthcare Institute for Neurosciences and Multiple Sclerosis, Owosso, Michigan
Mayo Clinic - Rochester, Rochester, Minnesota
Washington University School of Medicine in St. Louis, Saint Louis, Missouri
NYU Langone, New York, New York
Duke University Medical Center, Durham, North Carolina
University of Cincinnati, Cincinnati, Ohio
Cleveland Clinic Foundation, Cleveland, Ohio
OhioHealth Research Institute, Columbus, Ohio
Premier Neurology, Greenville, South Carolina
Baylor College of Medicine, Houston, Texas
Medical College of Wisconsin, Milwaukee, Wisconsin
Brain and Mind Research Institute, Camperdown, New South Wales
John Hunter Hospital, New Lambton, New South Wales
Sydney Children's Hospital, Randwick, New South Wales
Royal North Shore Hospital, St Leonards, New South Wales
Box Hill Hospital, Box Hill, Victoria
Monash Medical Centre, Clayton, Victoria
St Vincent's Hospital Melbourne, Fitzroy, Victoria
Royal Melbourne Hospital, Parkville, Victoria
Perron Institute for Neurological and Translational Science, Nedlands, Western Australia
Instituto de Neurologia de Curitiba, Curitiba, Paraná
Instituto do Cerebro do Rio Grande do Sul, Porto Alegre, Rio Grande Do Sul
Centro de Pesquisas Clinicas, Sao Paulo, São Paulo
Hospital Universitario Gaffree e Guinle, Rio de Janeiro, Not set
London Health Sciences Centre Uni Campus, London, Ontario
Children's Hospital of Eastern Ontario, Ottawa, Ontario
Unity Health Toronto - St. Michael's Hospital, Toronto, Ontario
The Hospital for Sick Children, Toronto, Ontario
MUCH - Montreal Neurological Institute & Hospital, Montreal, Quebec
Hopital Pierre Wertheimer, Bron, Not set
CH de Bicêtre, Le Kremlin Bicêtre, Not set
CHU de Toulouse - Hôpital Purpan, Toulouse, Not set
NeuroCure Clinical Research Center (NCRC), Berlin, Not set
St. Josef-Hospital, Klinik für Neurologie, Bochum, Not set
Vestische Kinder- und Jugendklinik Datteln, Datteln, Not set
Universitätsklinikum Düsseldorf, Düsseldorf, Not set
Neurology UKSH Campus Kiel, Kiel, Not set
Universitätsklinikum Mannheim, Mannheim, Not set
Klinikum Großhadern, LMU, Munich, Not set
Hadassah University Hospital Ein Kerem, Jerusalem, Not set
Ospedale Pediatrico Bambino Gesù, Roma, Lazio
IRCCS Ospedale San Raffaele, Milano, Lombardia
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Lombardia
Fondazione Istituto Neurologico Mondino IRCCS, Pavia, Lombardia
Azienda Sanitaria Ospedaliera S. Luigi Gonzaga, Orbassano, Piemonte
AOU Policlinico V. Emanuele - P.O G. Rodolico, Catania, Sicilia
Azienda Ospedaliera Universitaria Integrata Verona, Verona, Veneto
Chiba University Hospital, Chiba, Not set
Kyushu University Hospital, Fukuoka, Not set
Southern Tohoku Medical Clinic, Fukushima, Not set
Kobe University Hospital, Hyogo, Not set
Kitasato University Hospital, Kanagawa, Not set
Tohoku University Hospital, Miyagi, Not set
Tohoku Medical and Pharmaceutical University Hospital, Miyagi, Not set
The University of Osaka Hospital, Osaka, Not set
Saitama Medical Center, Saitama, Not set
The Jikei University Hospital, Tokyo, Not set
Juntendo University Hospital, Tokyo, Not set
Tokyo Medical University Hospital, Tokyo, Not set
Keio University Hospital, Tokyo, Not set
Tokyo Women's Medical University Hospital, Tokyo, Not set
National Cancer Center, Goyang-si, Not set
Seoul National University Hospital, Seoul, Not set
Samsung Medical Center, Seoul, Not set
NZOZ Wielospecjalistyczna Poradnia Lekarska SYNAPSIS, Katowice, Not set
Szpital Uniwersytecki w Krakowie, Kraków, Not set
Centrum Medyczne "MEDYK", Rzeszow, Not set
Klinika Neurologii I Wydzialu Lekarskiego WUM w Warszawie, Warszawa, Not set
SPSK nr 1, Zabrze, Not set
Conditions: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer
Recruiting
This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage III-IV head and neck cancer the begins in the thin, flat cells (squamous cell). Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in chemotherapy, such as cisplatin and docetaxel, wor... Read More
This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage III-IV head and neck cancer the begins in the thin, flat cells (squamous cell). Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in chemotherapy, such as cisplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Cetuximab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. The purpose of this study is to compare the usual treatment (radiation therapy with cisplatin chemotherapy) to using radiation therapy with docetaxel and cetuximab chemotherapy, and using the usual treatment plus an immunotherapy drug, atezolizumab. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2025
Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +325 locations
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama
The Kirklin Clinic at Acton Road, Birmingham, Alabama
Banner University Medical Center - Tucson, Tucson, Arizona
University of Arizona Cancer Center-North Campus, Tucson, Arizona
University of Arkansas for Medical Sciences, Little Rock, Arkansas
Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn, California
Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California
Sutter Cancer Centers Radiation Oncology Services-Cameron Park, Cameron Park, California
Mercy San Juan Medical Center, Carmichael, California
UC San Diego Health System - Encinitas, Encinitas, California
UC San Diego Moores Cancer Center, La Jolla, California
Cedars Sinai Medical Center, Los Angeles, California
Memorial Medical Center, Modesto, California
UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California
Stanford Cancer Institute Palo Alto, Palo Alto, California
Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California
Sutter Medical Center Sacramento, Sacramento, California
University of California Davis Comprehensive Cancer Center, Sacramento, California
Saint Helena Hospital, Saint Helena, California
UCSF Medical Center-Mount Zion, San Francisco, California
UCSF Medical Center-Mission Bay, San Francisco, California
Mills Health Center, San Mateo, California
UCHealth University of Colorado Hospital, Aurora, Colorado
Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado
Penrose-Saint Francis Healthcare, Colorado Springs, Colorado
AdventHealth Porter, Denver, Colorado
Shaw Cancer Center, Edwards, Colorado
Banner North Colorado Medical Center, Greeley, Colorado
Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado
Longmont United Hospital, Longmont, Colorado
Banner McKee Medical Center, Loveland, Colorado
AdventHealth Parker, Parker, Colorado
University of Connecticut, Farmington, Connecticut
Yale University, New Haven, Connecticut
Smilow Cancer Hospital Care Center - Waterford, Waterford, Connecticut
Helen F Graham Cancer Center, Newark, Delaware
Christiana Care Health System-Christiana Hospital, Newark, Delaware
George Washington University Medical Center, Washington, District of Columbia
UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida
Holy Cross Hospital, Fort Lauderdale, Florida
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
AdventHealth Orlando, Orlando, Florida
Orlando Health Cancer Institute, Orlando, Florida
Moffitt Cancer Center, Tampa, Florida
Emory University Hospital Midtown, Atlanta, Georgia
Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia
Augusta University Medical Center, Augusta, Georgia
Memorial Health University Medical Center, Savannah, Georgia
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia
Queen's Medical Center, Honolulu, Hawaii
The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii
Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho
Northwestern University, Chicago, Illinois
John H Stroger Jr Hospital of Cook County, Chicago, Illinois
Rush University Medical Center, Chicago, Illinois
University of Illinois, Chicago, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Crossroads Cancer Center, Effingham, Illinois
NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois
NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois
NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois
HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois
Advocate Christ Medical Center, Oak Lawn, Illinois
OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois
OSF Saint Francis Medical Center, Peoria, Illinois
UW Health Carbone Cancer Center Rockford, Rockford, Illinois
Springfield Memorial Hospital, Springfield, Illinois
Carle Cancer Center, Urbana, Illinois
Ascension Saint Vincent Anderson, Anderson, Indiana
Elkhart General Hospital, Elkhart, Indiana
Radiation Oncology Associates PC, Fort Wayne, Indiana
Parkview Hospital Randallia, Fort Wayne, Indiana
Parkview Regional Medical Center, Fort Wayne, Indiana
Goshen Center for Cancer Care, Goshen, Indiana
Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana
IU Health Methodist Hospital, Indianapolis, Indiana
IU Health Central Indiana Cancer Centers-East, Indianapolis, Indiana
Michiana Hematology Oncology PC-Mishawaka, Mishawaka, Indiana
Memorial Hospital of South Bend, South Bend, Indiana
McFarland Clinic - Ames, Ames, Iowa
Iowa Methodist Medical Center, Des Moines, Iowa
University of Kansas Cancer Center, Kansas City, Kansas
The University of Kansas Cancer Center - Olathe, Olathe, Kansas
University of Kansas Cancer Center-Overland Park, Overland Park, Kansas
Salina Regional Health Center, Salina, Kansas
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky
UofL Health Medical Center Northeast, Louisville, Kentucky
Tulane University School of Medicine, New Orleans, Louisiana
University Medical Center New Orleans, New Orleans, Louisiana
Touro Infirmary, New Orleans, Louisiana
Ochsner Medical Center Jefferson, New Orleans, Louisiana
University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland
Greater Baltimore Medical Center, Baltimore, Maryland
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
UM Upper Chesapeake Medical Center, Bel Air, Maryland
Central Maryland Radiation Oncology in Howard County, Columbia, Maryland
UM Baltimore Washington Medical Center/Tate Cancer Center, Glen Burnie, Maryland
Holy Cross Hospital, Silver Spring, Maryland
Boston Medical Center, Boston, Massachusetts
Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan
Trinity Health Medical Center - Brighton, Brighton, Michigan
University of Michigan - Brighton Center for Specialty Care, Brighton, Michigan
Henry Ford Cancer Institute-Downriver, Brownstown, Michigan
Henry Ford Macomb Hospital-Clinton Township, Clinton Township, Michigan
Henry Ford Hospital, Detroit, Michigan
Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids, Michigan
Allegiance Health, Jackson, Michigan
West Michigan Cancer Center, Kalamazoo, Michigan
University of Michigan Health - Sparrow Lansing, Lansing, Michigan
Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan
Henry Ford Medical Center-Columbus, Novi, Michigan
Corewell Health William Beaumont University Hospital, Royal Oak, Michigan
MyMichigan Medical Center Saginaw, Saginaw, Michigan
Corewell Health Beaumont Troy Hospital, Troy, Michigan
Henry Ford West Bloomfield Hospital, West Bloomfield, Michigan
University of Michigan Health - West, Wyoming, Michigan
Sanford Joe Lueken Cancer Center, Bemidji, Minnesota
Minnesota Oncology - Burnsville, Burnsville, Minnesota
Miller-Dwan Hospital, Duluth, Minnesota
Hennepin County Medical Center, Minneapolis, Minnesota
Mayo Clinic in Rochester, Rochester, Minnesota
Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota
University of Mississippi Medical Center, Jackson, Mississippi
Saint Francis Medical Center, Cape Girardeau, Missouri
MU Health - University Hospital/Ellis Fischel Cancer Center, Columbia, Missouri
Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri
North Kansas City Hospital, Kansas City, Missouri
The University of Kansas Cancer Center-South, Kansas City, Missouri
University of Kansas Cancer Center - North, Kansas City, Missouri
University of Kansas Cancer Center - Lee's Summit, Lee's Summit, Missouri
Phelps Health Delbert Day Cancer Institute, Rolla, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Siteman Cancer Center-South County, Saint Louis, Missouri
Missouri Baptist Medical Center, Saint Louis, Missouri
Mercy Hospital Saint Louis, Saint Louis, Missouri
Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri
Mercy Hospital Springfield, Springfield, Missouri
CoxHealth South Hospital, Springfield, Missouri
CHI Health Good Samaritan, Kearney, Nebraska
Nebraska Methodist Hospital, Omaha, Nebraska
Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey
The Cancer Institute of New Jersey Hamilton, Hamilton, New Jersey
Saint Barnabas Medical Center, Livingston, New Jersey
Monmouth Medical Center, Long Branch, New Jersey
Memorial Sloan Kettering Monmouth, Middletown, New Jersey
Memorial Sloan Kettering Bergen, Montvale, New Jersey
Virtua Memorial, Mount Holly, New Jersey
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Rutgers New Jersey Medical School, Newark, New Jersey
Robert Wood Johnson University Hospital Somerset, Somerville, New Jersey
Sparta Cancer Treatment Center, Sparta, New Jersey
Community Medical Center, Toms River, New Jersey
Virtua Voorhees, Voorhees, New Jersey
University of New Mexico Cancer Center, Albuquerque, New Mexico
New Mexico Oncology Hematology Consultants, Albuquerque, New Mexico
South Shore University Hospital, Bay Shore, New York
Montefiore Medical Center-Einstein Campus, Bronx, New York
Montefiore Medical Center - Moses Campus, Bronx, New York
New York-Presbyterian/Brooklyn Methodist Hospital, Brooklyn, New York
NYU Langone Hospital - Brooklyn, Brooklyn, New York
Roswell Park Cancer Institute, Buffalo, New York
Sands Cancer Center, Canandaigua, New York
Memorial Sloan Kettering Commack, Commack, New York
Arnot Ogden Medical Center/Falck Cancer Center, Elmira, New York
Memorial Sloan Kettering Westchester, Harrison, New York
Northwell Health/Center for Advanced Medicine, Lake Success, New York
NYU Langone Hospital - Long Island, Mineola, New York
Mount Sinai Union Square, New York, New York
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, New York
Wilmot Cancer Institute Radiation Oncology at Greece, Rochester, New York
Highland Hospital, Rochester, New York
University of Rochester, Rochester, New York
Memorial Sloan Kettering Sleepy Hollow, Sleepy Hollow, New York
State University of New York Upstate Medical University, Syracuse, New York
Memorial Sloan Kettering Nassau, Uniondale, New York
Atrium Health Stanly/LCI-Albemarle, Albemarle, North Carolina
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina
Atrium Health Pineville/LCI-Pineville, Charlotte, North Carolina
Atrium Health University City/LCI-University, Charlotte, North Carolina
Atrium Health Cabarrus/LCI-Concord, Concord, North Carolina
East Carolina University, Greenville, North Carolina
ECU Health Oncology Kinston, Kinston, North Carolina
Atrium Health Union/LCI-Union, Monroe, North Carolina
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Sanford Bismarck Medical Center, Bismarck, North Dakota
Sanford Roger Maris Cancer Center, Fargo, North Dakota
Summa Health System - Akron Campus, Akron, Ohio
Cleveland Clinic Akron General, Akron, Ohio
UH Seidman Cancer Center at UH Avon Health Center, Avon, Ohio
Summa Health System - Barberton Campus, Barberton, Ohio
UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio
Geauga Hospital, Chardon, Ohio
Adena Regional Medical Center, Chillicothe, Ohio
University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio
Case Western Reserve University, Cleveland, Ohio
MetroHealth Medical Center, Cleveland, Ohio
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio
Cleveland Clinic Foundation, Cleveland, Ohio
Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Mercy Cancer Center-Elyria, Elyria, Ohio
Cleveland Clinic Cancer Center Independence, Independence, Ohio
OhioHealth Mansfield Hospital, Mansfield, Ohio
Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio
Summa Health Medina Medical Center, Medina, Ohio
UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio
UH Seidman Cancer Center at Southwest General Hospital, Middleburg Heights, Ohio
University Hospitals Parma Medical Center, Parma, Ohio
Southern Ohio Medical Center, Portsmouth, Ohio
University Hospitals Portage Medical Center, Ravenna, Ohio
North Coast Cancer Care, Sandusky, Ohio
UH Seidman Cancer Center at Firelands Regional Medical Center, Sandusky, Ohio
Cleveland Clinic Cancer Center Strongsville, Strongsville, Ohio
University of Cincinnati Cancer Center-West Chester, West Chester, Ohio
UHHS-Westlake Medical Center, Westlake, Ohio
Cleveland Clinic Wooster Family Health and Surgery Center, Wooster, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Clackamas Radiation Oncology Center, Clackamas, Oregon
Providence Portland Medical Center, Portland, Oregon
Providence Saint Vincent Medical Center, Portland, Oregon
UPMC Altoona, Altoona, Pennsylvania
UPMC-Heritage Valley Health System Beaver, Beaver, Pennsylvania
Carlisle Regional Cancer Center, Carlisle, Pennsylvania
UPMC Hillman Cancer Center Erie, Erie, Pennsylvania
UPMC Cancer Center at UPMC Horizon, Farrell, Pennsylvania
UPMC Cancer Centers - Arnold Palmer Pavilion, Greensburg, Pennsylvania
UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg, Pennsylvania
Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania
IRMC Cancer Center, Indiana, Pennsylvania
UPMC-Johnstown/John P. Murtha Regional Cancer Center, Johnstown, Pennsylvania
UPMC Cancer Center at UPMC McKeesport, McKeesport, Pennsylvania
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg, Pennsylvania
UPMC Cancer Center - Monroeville, Monroeville, Pennsylvania
UPMC Hillman Cancer Center in Coraopolis, Moon, Pennsylvania
UPMC Cancer Center-Natrona Heights, Natrona Heights, Pennsylvania
UPMC Jameson, New Castle, Pennsylvania
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Fox Chase Cancer Center, Philadelphia, Pennsylvania
Temple University Hospital, Philadelphia, Pennsylvania
Allegheny General Hospital, Pittsburgh, Pennsylvania
UPMC-Magee Womens Hospital, Pittsburgh, Pennsylvania
UPMC-Saint Margaret, Pittsburgh, Pennsylvania
UPMC-Shadyside Hospital, Pittsburgh, Pennsylvania
UPMC Jefferson Regional Radiation Oncology, Pittsburgh, Pennsylvania
UPMC-Passavant Hospital, Pittsburgh, Pennsylvania
UPMC-Saint Clair Hospital Cancer Center, Pittsburgh, Pennsylvania
UPMC Cancer Center at UPMC Northwest, Seneca, Pennsylvania
UPMC Uniontown Hospital Radiation Oncology, Uniontown, Pennsylvania
UPMC Washington Hospital Radiation Oncology, Washington, Pennsylvania
Reading Hospital, West Reading, Pennsylvania
Wexford Health and Wellness Pavilion, Wexford, Pennsylvania
AnMed Health Cancer Center, Anderson, South Carolina
Saint Joseph's/Candler - Bluffton Campus, Bluffton, South Carolina
Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina
Medical University of South Carolina, Charleston, South Carolina
Prisma Health Cancer Institute - Faris, Greenville, South Carolina
Prisma Health Cancer Institute - Eastside, Greenville, South Carolina
Prisma Health Cancer Institute - Greer, Greer, South Carolina
Gibbs Cancer Center-Pelham, Greer, South Carolina
Rock Hill Radiation Therapy Center, Rock Hill, South Carolina
Prisma Health Cancer Institute - Seneca, Seneca, South Carolina
Spartanburg Medical Center, Spartanburg, South Carolina
Rapid City Regional Hospital, Rapid City, South Dakota
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee
MD Anderson in The Woodlands, Conroe, Texas
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
University of Texas Medical Branch, Galveston, Texas
M D Anderson Cancer Center, Houston, Texas
MD Anderson West Houston, Houston, Texas
MD Anderson League City, League City, Texas
UTMB Cancer Center at Victory Lakes, League City, Texas
Covenant Medical Center-Lakeside, Lubbock, Texas
MD Anderson in Sugar Land, Sugar Land, Texas
Intermountain Medical Center, Murray, Utah
Saint George Regional Medical Center, Saint George, Utah
Utah Cancer Specialists-Salt Lake City, Salt Lake City, Utah
Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah
Dartmouth Cancer Center - North, Saint Johnsbury, Vermont
Inova Fairfax Hospital, Falls Church, Virginia
Sentara Cancer Institute at Sentara CarePlex Hospital, Hampton, Virginia
Sentara Norfolk General Hospital, Norfolk, Virginia
VCU Massey Comprehensive Cancer Center, Richmond, Virginia
Sentara Virginia Beach General Hospital, Virginia Beach, Virginia
Saint Francis Hospital, Federal Way, Washington
Tri-Cities Cancer Center, Kennewick, Washington
PeaceHealth Saint John Medical Center, Longview, Washington
Skagit Regional Health Cancer Care Center, Mount Vernon, Washington
University of Washington Medical Center - Montlake, Seattle, Washington
Spokane Valley Cancer Center-Mayfair, Spokane, Washington
Spokane Valley Cancer Center-Mission, Spokane, Washington
Wenatchee Valley Hospital and Clinics, Wenatchee, Washington
West Virginia University Healthcare, Morgantown, West Virginia
Camden Clark Medical Center, Parkersburg, West Virginia
Wheeling Hospital/Schiffler Cancer Center, Wheeling, West Virginia
Langlade Hospital and Cancer Center, Antigo, Wisconsin
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin
Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin
University of Wisconsin Carbone Cancer Center - Johnson Creek, Johnson Creek, Wisconsin
Gundersen Lutheran Medical Center, La Crosse, Wisconsin
Mayo Clinic Health System-Franciscan Healthcare, La Crosse, Wisconsin
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin
University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin
Bay Area Medical Center, Marinette, Wisconsin
Marshfield Medical Center, Marshfield, Wisconsin
Froedtert Menomonee Falls Hospital, Menomonee Falls, Wisconsin
Medical College of Wisconsin, Milwaukee, Wisconsin
Marshfield Medical Center - Minocqua, Minocqua, Wisconsin
Cancer Center of Western Wisconsin, New Richmond, Wisconsin
Drexel Town Square Health Center, Oak Creek, Wisconsin
Aspirus Cancer Care - James Beck Cancer Center, Rhinelander, Wisconsin
Aspirus Cancer Care - Stevens Point, Stevens Point, Wisconsin
Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin
Aspirus Regional Cancer Center, Wausau, Wisconsin
Froedtert West Bend Hospital/Kraemer Cancer Center, West Bend, Wisconsin
Aspirus Cancer Care - Wisconsin Rapids, Wisconsin Rapids, Wisconsin
Cross Cancer Institute, Edmonton, Alberta
Allan Blair Cancer Centre, Regina, Saskatchewan
Saskatoon Cancer Centre, Saskatoon, Saskatchewan
Chinese University of Hong Kong-Prince of Wales Hospital, Shatin, Not set
Conditions: Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7, Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7, Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7, Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
Recruiting
This phase I/II trial tests the safety, side effects, and best dose of selinexor given in combination with standard radiation therapy in treating children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG) with a genetic change called H3 K27M mutation. It also tests whether combination of selinexor and standard radiation therapy works to shrink tumors in this patient population. Glioma is a type of cancer that occurs in the brain or spine. Gl... Read More
This phase I/II trial tests the safety, side effects, and best dose of selinexor given in combination with standard radiation therapy in treating children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG) with a genetic change called H3 K27M mutation. It also tests whether combination of selinexor and standard radiation therapy works to shrink tumors in this patient population. Glioma is a type of cancer that occurs in the brain or spine. Glioma is considered high risk (or high-grade) when it is growing and spreading quickly. The term, risk, refers to the chance of the cancer coming back after treatment. DIPG is a subtype of HGG that grows in the pons (a part of the brainstem that controls functions like breathing, swallowing, speaking, and eye movements). This trial has two parts. The only difference in treatment between the two parts is that some subjects treated in Part 1 may receive a different dose of selinexor than the subjects treated in Part 2. In Part 1 (also called the Dose-Finding Phase), investigators want to determine the dose of selinexor that can be given without causing side effects that are too severe. This dose is called the maximum tolerated dose (MTD). In Part 2 (also called the Efficacy Phase), investigators want to find out how effective the MTD of selinexor is against HGG or DIPG. Selinexor blocks a protein called CRM1, which may help keep cancer cells from growing and may kill them. It is a type of small molecule inhibitor called selective inhibitors of nuclear export (SINE). Radiation therapy uses high energy to kill tumor cells and shrink tumors. The combination of selinexor and radiation therapy may be effective in treating patients with newly-diagnosed DIPG and H3 K27M-Mutant HGG. Read Less
Gender:
ALL
Ages:
Between 12 months and 21 years
Trial Updated:
08/22/2025
Locations: Children's Hospital of Alabama, Birmingham, Alabama +123 locations
Children's Hospital of Alabama, Birmingham, Alabama
Banner Children's at Desert, Mesa, Arizona
Phoenix Childrens Hospital, Phoenix, Arizona
Arkansas Children's Hospital, Little Rock, Arkansas
Loma Linda University Medical Center, Loma Linda, California
Miller Children's and Women's Hospital Long Beach, Long Beach, California
Children's Hospital Los Angeles, Los Angeles, California
Cedars Sinai Medical Center, Los Angeles, California
UCSF Benioff Children's Hospital Oakland, Oakland, California
Kaiser Permanente-Oakland, Oakland, California
Children's Hospital of Orange County, Orange, California
Lucile Packard Children's Hospital Stanford University, Palo Alto, California
Rady Children's Hospital - San Diego, San Diego, California
UCSF Medical Center-Mission Bay, San Francisco, California
Children's Hospital Colorado, Aurora, Colorado
Connecticut Children's Medical Center, Hartford, Connecticut
Yale University, New Haven, Connecticut
Alfred I duPont Hospital for Children, Wilmington, Delaware
Children's National Medical Center, Washington, District of Columbia
Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida
Nemours Children's Clinic-Jacksonville, Jacksonville, Florida
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
Miami Cancer Institute, Miami, Florida
Arnold Palmer Hospital for Children, Orlando, Florida
Nemours Children's Hospital, Orlando, Florida
Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii
Saint Luke's Cancer Institute - Boise, Boise, Idaho
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Saint Jude Midwest Affiliate, Peoria, Illinois
Riley Hospital for Children, Indianapolis, Indiana
Blank Children's Hospital, Des Moines, Iowa
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
Norton Children's Hospital, Louisville, Kentucky
Children's Hospital New Orleans, New Orleans, Louisiana
Eastern Maine Medical Center, Bangor, Maine
Maine Children's Cancer Program, Scarborough, Maine
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
Dana-Farber Cancer Institute, Boston, Massachusetts
C S Mott Children's Hospital, Ann Arbor, Michigan
Children's Hospital of Michigan, Detroit, Michigan
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan
Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota
University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota
University of Mississippi Medical Center, Jackson, Mississippi
Children's Mercy Hospitals and Clinics, Kansas City, Missouri
Cardinal Glennon Children's Medical Center, Saint Louis, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Mercy Hospital Saint Louis, Saint Louis, Missouri
Children's Hospital and Medical Center of Omaha, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
Hackensack University Medical Center, Hackensack, New Jersey
Morristown Medical Center, Morristown, New Jersey
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey
Newark Beth Israel Medical Center, Newark, New Jersey
Saint Joseph's Regional Medical Center, Paterson, New Jersey
Albany Medical Center, Albany, New York
Montefiore Medical Center - Moses Campus, Bronx, New York
Roswell Park Cancer Institute, Buffalo, New York
The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, New York
State University of New York Upstate Medical University, Syracuse, New York
Novant Health Presbyterian Medical Center, Charlotte, North Carolina
East Carolina University, Greenville, North Carolina
Wake Forest University Health Sciences, Winston-Salem, North Carolina
Sanford Broadway Medical Center, Fargo, North Dakota
Children's Hospital Medical Center of Akron, Akron, Ohio
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Rainbow Babies and Childrens Hospital, Cleveland, Ohio
Nationwide Children's Hospital, Columbus, Ohio
Dayton Children's Hospital, Dayton, Ohio
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Legacy Emanuel Children's Hospital, Portland, Oregon
Oregon Health and Science University, Portland, Oregon
Geisinger Medical Center, Danville, Pennsylvania
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania
Rhode Island Hospital, Providence, Rhode Island
Prisma Health Richland Hospital, Columbia, South Carolina
BI-LO Charities Children's Cancer Center, Greenville, South Carolina
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota
East Tennessee Childrens Hospital, Knoxville, Tennessee
Saint Jude Children's Research Hospital, Memphis, Tennessee
The Children's Hospital at TriStar Centennial, Nashville, Tennessee
Dell Children's Medical Center of Central Texas, Austin, Texas
Medical City Dallas Hospital, Dallas, Texas
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
El Paso Children's Hospital, El Paso, Texas
Cook Children's Medical Center, Fort Worth, Texas
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas
M D Anderson Cancer Center, Houston, Texas
Children's Hospital of San Antonio, San Antonio, Texas
University of Texas Health Science Center at San Antonio, San Antonio, Texas
Primary Children's Hospital, Salt Lake City, Utah
University of Virginia Cancer Center, Charlottesville, Virginia
Children's Hospital of The King's Daughters, Norfolk, Virginia
Seattle Children's Hospital, Seattle, Washington
Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington
Mary Bridge Children's Hospital and Health Center, Tacoma, Washington
University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin
Children's Hospital of Wisconsin, Milwaukee, Wisconsin
Sydney Children's Hospital, Randwick, New South Wales
The Children's Hospital at Westmead, Westmead, New South Wales
Queensland Children's Hospital, South Brisbane, Queensland
Royal Children's Hospital, Parkville, Victoria
Perth Children's Hospital, Perth, Western Australia
University of Alberta Hospital, Edmonton, Alberta
British Columbia Children's Hospital, Vancouver, British Columbia
CancerCare Manitoba, Winnipeg, Manitoba
IWK Health Centre, Halifax, Nova Scotia
Hospital for Sick Children, Toronto, Ontario
The Montreal Children's Hospital of the MUHC, Montreal, Quebec
Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec
Jim Pattison Children's Hospital, Saskatoon, Saskatchewan
CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set
Starship Children's Hospital, Grafton, Auckland
Christchurch Hospital, Christchurch, Not set
Conditions: Malignant Glioma
A Trial of Felzartamab in Kidney Transplant Recipients With Late Antibody-Mediated Rejection (AMR)
Recruiting
The main goal of this trial is to evaluate the efficacy of felzartamab compared to placebo in kidney transplant recipients diagnosed with late active or chronic active AMR.
The main goal of this trial is to evaluate the efficacy of felzartamab compared to placebo in kidney transplant recipients diagnosed with late active or chronic active AMR. Read Less
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/22/2025
Locations: University of Southern California, Los Angeles, California +35 locations
University of Southern California, Los Angeles, California
UCLA, Los Angeles, California
Providence Healthcare, Orange, California
Loma Linda, San Bernardino, California
California Pacific Medical Center, San Francisco, California
University of Colorado, Aurora, Colorado
University of Chicago, Chicago, Illinois
University of Kansas, Kansas City, Kansas
Tulane University Health Sciences Center, New Orleans, Louisiana
Mayo Clinic, Rochester, Minnesota
Washington University, Saint Louis, Missouri
University of Nebraska, Omaha, Nebraska
Cooperman Barnabas Medical Center, West Orange, New Jersey
Duke University, Durham, North Carolina
University of Cincinnati, Cincinnati, Ohio
Cleveland Clinic, Cleveland, Ohio
The Ohio State University, Columbus, Ohio
Penn Medicine - Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
Vanderbilt University, Nashville, Tennessee
UT Southwestern Medical Center, Dallas, Texas
Houston Methodist, Houston, Texas
Virginia Commonwealth University, Richmond, Virginia
University of Washington Medical Center, Seattle, Washington
Medical College of Wisconsin, Milwaukee, Wisconsin
Westmead Hospital, Sydney, New South Wales
Medical University of Vienna, Spitalgasse, Vienna
Fundação Oswaldo Ramos - Hospital do Rim (HRIM), Vila Clementino, Sao Paulo
University of Alberta, Edmonton, Alberta
Vancouver General Hospital, Vancouver, British Columbia
The University of British Columbia (UBC)/St. Paul's Hospital part of Providence Health Care, Vancouver, British Columbia
McGill, Montreal, Quebec
Charite University, Berlin, Not set
Universitatsklinikum Hamburg-Eppendorf, Hamburg, Not set
Hospital del Mar, Ciutat Vella, Barcelona
Hospital Universitario Vall d'Hebron, Horta-Guinardó, Barcelona
University Hospital Basel, Petersgraben, Basel
Conditions: Antibody-mediated Rejection
A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)
Recruiting
This study is open to adults with different types of advanced cancer (solid tumors) that are accessible for injection and/or biopsy. This is a study for people with a life expectancy of at least 3 months after starting study treatment. The purpose of this study is to find the highest dose of a medicine called BI 1831169 that people with advanced cancer can tolerate when taken with or without a type of antibody called a checkpoint inhibitor (anti-PD-1 antibody). Another purpose is to check whethe... Read More
This study is open to adults with different types of advanced cancer (solid tumors) that are accessible for injection and/or biopsy. This is a study for people with a life expectancy of at least 3 months after starting study treatment. The purpose of this study is to find the highest dose of a medicine called BI 1831169 that people with advanced cancer can tolerate when taken with or without a type of antibody called a checkpoint inhibitor (anti-PD-1 antibody). Another purpose is to check whether the study treatment can fight cancer. In this study, BI 1831169 is given to people for the first time.
This study has 2 parts. In Part 1, participants get BI 1831169 alone for up to 3 months. In Part 2, participants get BI 1831169 in combination with a checkpoint inhibitor. Participants who take the combination treatment get BI 1831169 for up to 3 months and a checkpoint inhibitor for up to 1 year. BI 1831169 is given as an injection into the tumor, or as an infusion into the vein, or both (injection and infusion). Checkpoint inhibitors are given as an infusion into a vein. Participants get the medicines about every 3 weeks. This is called a treatment cycle.
Participants visit the site study site regularly. The number of study visits vary based on the study phase and treatment response. Some visits include an overnight stay. The doctors regularly check the participants' health and monitor the tumors. The doctors also take note of any health problems that could have been caused by the study treatment. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2025
Locations: Banner MD Anderson Cancer Center-Gilbert-55251, Gilbert, Arizona +40 locations
Banner MD Anderson Cancer Center-Gilbert-55251, Gilbert, Arizona
University of Arizona, Tucson, Arizona
University of California San Diego, La Jolla, California
Providence St. John's Health Center, Santa Monica, California
University of Colorado Denver, Aurora, Colorado
University of Miami, Miami, Florida
Orlando Health Cancer Institute, Orlando, Florida
Winship Cancer Institute, Atlanta, Georgia
University of Louisville, Louisville, Kentucky
M Health Fairview University of Minnesota Medical Center, Minneapolis, Minnesota
Morristown Medical Center, Morristown, New Jersey
Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina
Prisma Health, Greenville, South Carolina
The University of Texas MD Anderson Cancer Center, Houston, Texas
University of Virginia Health System, Charlottesville, Virginia
Southern Oncology Clinical Research Unit, Bedford Park, South Australia
Peninsula Haematology & Oncology, Frankston, Victoria
Medical University of Innsbruck, Innsbruck, Not set
Salzburg Cancer Research Institute, Salzburg, Not set
Edegem - UNIV UZ Antwerpen, Edegem, Not set
UNIV UZ Gent, Gent, Not set
UZ Leuven, Leuven, Not set
Princess Margaret Cancer Centre, Toronto, Ontario
INS Bergonie, Bordeaux, Not set
HOP Timone, Marseille, Not set
CTR Eugène Marquis, Rennes, Not set
INS Gustave Roussy, Villejuif, Not set
Charite Universitätsmedizin Berlin KöR, Berlin, Not set
Universitätsklinikum Heidelberg, Heidelkberg, Not set
Universitätsklinikum Tübingen, Tübingen, Not set
Universitätsklinikum Ulm, Ulm, Not set
Istituto Di Candiolo, Candiolo (TO), Not set
ASST Grande Ospedale Metropolitano Niguarda, Milano, Not set
Azienda Ospedaliera Universitaria Integrata Verona, Verona, Not set
Hospital Quiron. I.C.U., Barcelona, Not set
Hospital Duran i Reynals, L'Hospitalet de Llobregat, Not set
Fundación Jiménez Díaz, Madrid, Not set
Clínica Universidad de Navarra, Pamplona, Not set
Instituto Valenciano de Oncología, Valencia, Not set
University Hospital Bern/Inselspital Bern, Bern, Not set
University Hospital Geneva, Geneve, Not set
Conditions: Solid Tumors
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR
Recruiting
The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart failure with functional regurgitation (FMR).
The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart failure with functional regurgitation (FMR). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2025
Locations: Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers, Gilbert, Arizona +70 locations
Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers, Gilbert, Arizona
Banner Health - Phoenix, Phoenix, Arizona
Tucson Medical Center Health, Tucson, Arizona
Banner University Tuscon, Tucson, Arizona
Memorial Care Hospital, Long Beach, California
Keck School of Medicine of USC, Los Angeles, California
UCLA Medical Center, Los Angeles, California
Stanford University, Redwood City, California
Scripps Health, San Diego, California
University of California- San Francisco, San Francisco, California
South Denver Cardiology, Littleton, Colorado
Medstar, Washington, District of Columbia
Delray Medical Center, Delray Beach, Florida
University of Miami, Miami, Florida
Advent Health Hospital, Orlando, Florida
Palm Beach Gardens Medical, Palm Beach, Florida
Tallahassee Research Institute, Tallahassee, Florida
Tampa General Hospital, Tampa, Florida
Augusta University Research Institute, Augusta, Georgia
Wellstar Health System,, Marietta, Georgia
Advocate Good Samaritan, Downers Grove, Illinois
Midwest Cardiovascular Institute (MCI), Naperville, Illinois
Prairie Heart Institute, Springfield, Illinois
Community Health Network, Indianapolis, Indiana
Cardiovascular Institute South, Houma, Louisiana
Ochsner Health System, New Orleans, Louisiana
Johns Hopkins, Baltimore, Maryland
St Elizabeth's Medical Center, Boston, Massachusetts
Massachusetts General Hospital, Boston, Massachusetts
Beth Israel Deaconess, Boston, Massachusetts
University of Michigan, Ann Arbor, Michigan
Ascension St. Marys Research Institute, Saginaw, Michigan
CentraCare Heart and Vascular, Saint Cloud, Minnesota
Deborah Heart & Lung, Browns Mills, New Jersey
Hackensack University Medical Center, Edison, New Jersey
Albany Medical College,, Albany, New York
University at Buffalo, Buffalo, New York
Vassar Brothers- Hudson Valley Cardiovascular Practice, Poughkeepsie, New York
Lindner Research Center at the Christ Hospital, Cincinnati, Ohio
Harrington Vascular, Cleveland, Ohio
Cleveland Clinic, Cleveland, Ohio
The Ohio State University, Columbus, Ohio
Kettering Health Research Institute, Dayton, Ohio
Oklahoma Heart Institute Hospital, Tulsa, Oklahoma
Saint Francis Hospital,, Tulsa, Oklahoma
Oregon Health & Science University (OHSU), Portland, Oregon
Providence Heart Institute, Portland, Oregon
Geisinger Medical Center, Danville, Pennsylvania
Penn Medicine Lancaster General Health, Lancaster, Pennsylvania
University of Pennsylvania, Philadelphia, Pennsylvania
Thomas Jefferson University, Philadelphia, Pennsylvania
Allegheny Health Network, Pittsburg, Pennsylvania
Lankenau Institute of Medical Research, Wynnewood, Pennsylvania
North Central Heart-Avera, Sioux Falls, South Dakota
Centennial Medical Center, Nashville, Tennessee
University of Virginia Health System, Charlottesville, Virginia
Henrico Doctors Hospital, Henrico, Virginia
Carilion Hospital, Roanoke, Virginia
Advocate Aurora Research Institute, Milwaukee, Wisconsin
University of Alberta, Edmonton, Alberta
St Boniface Hospital - University of Manitoba, Winnipeg, Manitoba
Toronto General Hospital, Toronto, Ontario
Unity Health Toronto, St Michael's Hospital, Toronto, Ontario
Pole Sante Republique, Clermont Ferrand, Not set
Centre Hospitalier Universitaire De Lille, Lille, Not set
Hôpital Cardiologique Louis Pradel, Lyon, Not set
Clinique du Millènaire Montpelier, Montpellier, Not set
Hôpital Européen Georges-Pompidou, Paris, Not set
European Interbalkan Medical Center, Thessaloníki, Not set
Poznan University of Medical Sciences, Poznan, Not set
St James University Hospital, Leeds, Not set
Conditions: Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases
A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3)
Recruiting
This study is designed to evaluate the long-term efficacy and safety of mirikizumab in participants with moderately to severely active ulcerative colitis (UC). The study will last up to 3 years. Participants who complete the 3-year study may continue to receive mirikizumab until it is (outside of this study) in their country or until they meet other discontinuation criteria.
This study is designed to evaluate the long-term efficacy and safety of mirikizumab in participants with moderately to severely active ulcerative colitis (UC). The study will last up to 3 years. Participants who complete the 3-year study may continue to receive mirikizumab until it is (outside of this study) in their country or until they meet other discontinuation criteria. Read Less
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/22/2025
Locations: Digestive Health Specialists, Dothan, Alabama +361 locations
Digestive Health Specialists, Dothan, Alabama
Research Solutions of Arizona, Litchfield Park, Arizona
Valleywise Health Medical Center, Phoenix, Arizona
InSite Digestive Health Care, Arcadia, California
Care Access - Berkeley, Berkeley, California
University of California San Diego, La Jolla, California
Om Research LLC, Lancaster, California
California Medical Research Associates, Northridge, California
Inland Empire Clinical Trials, LLC, Rialto, California
Clinical Applications Laboratories, Inc., San Diego, California
Direct Helpers Research Center, Hialeah, Florida
Encore Borland-Groover Clinical Research, Jacksonville, Florida
Wellness Clinical Research, Miami Lakes, Florida
AdventHealth Orlando, Orlando, Florida
Clintheory Healthcare, Orlando, Florida
Gastroenterology Associates of Pensacola, PA, Pensacola, Florida
Florida Medical Clinic LLC, Zephyrhills, Florida
Digestive Healthcare of Georgia, Atlanta, Georgia
Grand Teton Research Group, Idaho Falls, Idaho
NorthShore University HealthSystem - Evanston Hospital, Evanston, Illinois
Indiana University Health University Hospital, Indianapolis, Indiana
Cotton O'Neil Digestive Health Center, Topeka, Kansas
GI Alliance Research Baton Rouge, Baton Rouge, Louisiana
Delta Research Partners, Monroe, Louisiana
Nola Research Works, LLC, New Orleans, Louisiana
University of Michigan, Ann Arbor, Michigan
Clinical Research Institute of Michigan, LLC, Chesterfield, Michigan
Henry Ford Medical Center - Columbus Center, Novi, Michigan
West Michigan Clinical Research Center, Wyoming, Michigan
MNGI Digestive Health - Plymouth Endoscopy Center & Clinic, Plymouth, Minnesota
NYU Langone Long Island Clinical Research Associates, Great Neck, New York
Columbia University Medical Center, New York, New York
Clinical & Translational Research Center (CTRC), Chapel Hill, North Carolina
Carolina Digestive Diseases and Endoscopy Center, Greenville, North Carolina
Care Access - Youngstown, Poland, Ohio
The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Central Sooner Research - Oklahoma - Northwest 47th Street, Oklahoma City, Oklahoma
Care Access - Pottsville, Pottsville, Pennsylvania
Digestive Disease Associates, Wyomissing, Pennsylvania
Midwest Medical Care, Sioux Falls, South Dakota
GI Alliance, Garland, Texas
Baylor College of Medicine, Houston, Texas
Biopharma Informatic, LLC, Houston, Texas
Gastroenterology Research of San Antonio, San Antonio, Texas
Southern Star Research Institute, San Antonio, Texas
GI Alliance, Southlake, Texas
Texas Digestive Disease Consultants, Southlake, Texas
Care Access-Ogden, Ogden, Utah
Care Access Research LLC - Salt Lake City, Salt Lake City, Utah
Carilion Clinic, Roanoke, Virginia
Washington Gastroenterology - Tacoma, Tacoma, Washington
Mautalen Salud e Investigación, Buenos Aires, Not set
CER medical Institute, Quilmes, Not set
Fundacion Estudios Clinicos, Rosario, Not set
Centro de Investigaciones Médicas Tucuman, SAN M. DE Tucuman, Not set
C.I.C.E. 9 de Julio, San Miguel de Tucumán, Not set
Royal Adelaide Hospital, Adelaide, Not set
Box Hill Hospital, Box Hill, Not set
Mater Misericordiae Limited, Brisbane, Not set
Princess Alexandra Hospital, Brisbane, Not set
Coastal Digestive Health, Maroochydore, Not set
St Vincent's Hospital, Melbourne, Not set
The Royal Melbourne Hospital, Parkville, Not set
Medizinische Universitaet Innsbruck, Innsbruck, Not set
Uniklinikum Salzburg, Salzburg, Not set
Universitaetsklinikum Allgemeines Krankenhaus Wien, Vienna, Not set
UZ Gent, Gent, Not set
UZ Leuven, Leuven, Not set
Centre Hospitalier de Wallonie Picarde - Site Notre Dame, Tournai, Not set
CISSS de la Monteregie-Centre, Greenfield Park, Not set
Victoria Hospital, London, Not set
University Hospital - London Health Sciences Centre, London, Not set
CIUSSS de l'Est-de-l'Île-de-Montréal, Montreal, Not set
Montreal General Hospital, Montreal, Not set
Fraser Clinical Trials Inc, New Westminster, Not set
Vancouver General Hospital, Vancouver, Not set
GIRI GI Research Institute - Vancouver, Vancouver, Not set
PerCuro Clinical Research, Victoria, Not set
Xiangya Hospital Central South University, Changsha, Not set
Changzhou No.2 People's Hospital, Changzhou, Not set
West China Hospital of Sichuan University, Cheng Du, Not set
The First Affiliated Hospital Of Fujian Medical University, Fuzhou, Not set
The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Not set
Hainan General Hospital, Haikou, Not set
The First Affiliated Hospital, Zhejiang University, Hangzhou, Not set
Sir Run Run Shaw Hospital, Hangzhou, Not set
The Second Affiliated hospital of Zhejiang University school of medicine, Hangzhou, Not set
The First Affiliated Hospital of Anhui Medical University, Hefei, Not set
Anhui Provincial Hospital, Hefei, Not set
Center-Jilin Center Hospital, Jilin, Not set
Shandong Provincial Hospital, Jinan, Not set
Shandong Provincial Hospital, Jinan, Not set
Qilu Hospital of Shandong University, Jinan, Not set
First Affiliated Hospital of Kunming Medical University, Kunming, Not set
The First People's Hospital of Yunnan Province, Kunming, Not set
Liaocheng People's Hospital, Liaocheng, Not set
The First Affiliated Hospital of Nanchang University, Nanchang, Not set
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School, Nanjing, Not set
Zhongda Hospital Southeast University, Nanjing, Not set
Jiangsu Province Hospital, Nanjing, Not set
Nanjing Medical University - Nanjing Jiangning Hospital, Nanjing, Not set
Jiangxi Pingxiang People's Hospital, Pingxiang, Not set
The Affiliated Hospital of Qingdao University, Qingdao, Not set
Renji Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, Not set
Shanghai Jiaotong University School of Medicine Ruijin Hospital, Shanghai, Not set
Shengjing Hospital of China Medical University, Shenyang, Not set
The Second Afilliated Hospital of Hebei Medical University, Shijiazhuang, Not set
Taian City Central Hospital, Taian, Not set
The 2nd Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Not set
Wuhan Union Hospital, Wuhan, Not set
Tongji Hospital Tongji Medical,Science & Technology, Wuhan, Not set
Renmin Hospital of Wuhan University, Wuhan, Not set
The Second Affiliated Hospital of Zhengzhou University, Zhengzhou Shi, Not set
ZhuZhou Central Hospital, Zhuzhou, Not set
Vojenská Nemocnice Brno, Brno, Not set
Fakultni Nemocnice u sv. Anny v Brne, Brno, Not set
Hepato-Gastroenterologie HK, Hradec Kralove, Not set
MUDr. Gregar, s.r.o., Olomouc, Not set
PreventaMed, Olomouc, Not set
A-Shine, Pilsen, Not set
Fakultni nemocnice Kralovske Vinohrady, Praha 10, Not set
MEDIENDO, Praha 8, Not set
ISCARE klinicke centrum, Praha 9, Not set
Herlev and Gentofte Hospital, Copenhagen, Not set
Sjællands Universitetshospital Køge, Køge, Not set
Sygehusenheden Nyborg, Nyborg, Not set
CHU d'Amiens-Picardie - Hôpital Sud, Amiens, Not set
CHRU Troussau, Chambray Les Tours, Not set
Hopital Claude Huriez - CHU de Lille, Lille, Not set
Chu Saint Eloi, Montpellier, Not set
Centres Médico Chirurgicaux - Clinique Ambroise Paré, Neuilly-sur-Seine, Not set
Centre Hospitalier Universitaire de Nice - Hôpital l'Archet, Nice, Not set
Hôpital Saint-Louis, Paris, Not set
Centre Hospitalier de Pau, Pau, Not set
CHU Bordeaux Haut-Leveque, Pessac, Not set
Centre Hospitalier Lyon Sud, Pierre-Bénite, Not set
Centre Hospitalier Universitaire de Saint Étienne - Hôpital Nord, Saint Priest En Jarez, Not set
Nouvel Hôpital Civil (NHC), Strasbourg, Not set
Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois, Vandoeuvre lès Nancy, Not set
LLC ARENSIA Exploratory Medicine, Tbilisi, Not set
Charite Universitätsmedizin Berlin Campus Benjamin Franklin, Berlin, Not set
Krankenhaus Waldfriede, Berlin, Not set
Städtisches Klinikum Brandenburg, Brandenburg, Not set
Studiengesellschaft BSF Unternehmergesellschaft, Halle (Saale), Not set
Universitätsklinikum Halle, Halle, Not set
HaFCED e.K. - Hamburgisches Forschungsinstitut für chronisch entzündliche Darmerkrankungen, Hamburg, Not set
Medizinische Hochschule Hannover, Hannover, Not set
Haus der Gesundheit, Ludwigshafen, Not set
Semmelweis University, Budapest, Not set
Eszak-budai Szent Janos Centrumkorhaz, Budapest, Not set
Békés Megyei Központi Kórház Dr. Réthy Pál Tagkórház, Békéscsaba, Not set
Petz Aladar Egyetemi Oktato Korhaz, Győr, Not set
Endomedix Diagnosztikai Központ - Miskolc, Miskolc, Not set
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ, Szeged, Not set
CLINFAN Szolgáltató Kft, Szekszárd, Not set
Jávorszky Ödön Kórház, Vác, Not set
Apollo Hospitals Ahmedabad, Ahmedabad, Not set
M S Ramaiah Medical College and Hospitals, Bangalore, Not set
Owaisi Hospital and Research Center, Hyderabad, Not set
SR Kalla Memorial Gastro & General Hospital, Jaipur, Not set
Dayanand Medical College and Hospital, Ludhiana, Not set
Midas Multispeciality Hospital Pvt.Ltd., Nagpur, Not set
Fortis Hospital, Noida, Not set
Grant Medical Foundation - Ruby Hall Clinic, Pune, Not set
Shree Giriraj Multispeciality Hospital, Rajkot, Not set
Gandhi Hospital, Secunderabad, Not set
Nirmal Hospital, Surat, Not set
Acharya Vinoba Bhave Rural Hospital, Wardha, Not set
Beaumont Hospital, Dublin, Dublin, Not set
Soroka Medical Center, Be'er Sheva, Not set
Shaare Zedek Medical Center, Jerusalem, Not set
Galilee Medical Center, Nahariya, Not set
Kaplan Medical Center, Rehovot, Not set
Sourasky Medical Center, Tel Aviv, Not set
Yitzhak Shamir Medical Center, Zerifin, Not set
Azienda Ospedaliera Mater Domini, Catanzaro, Not set
Ospedale San Martino, Genova, Not set
Azienda Ospedaliera Universitaria Pisana, Pisa, Not set
Ospedale Di Circolo, Rho, Not set
Fondazione Policlinico Tor Vergata, Roma, Not set
Fondazione Policlinico Universitario Agostino Gemelli, Roma, Not set
Ospedale Sandro Pertini, Rome, Not set
Humanitas, Rozzano, Not set
Ospedale Mauriziano, Torino, Not set
Asahikawa City Hospital, Asahikawa, Not set
Juntendo University Hospital, Bunkyo-ku, Not set
Tokyo Medical and Dental University Hospital, Bunkyō, Not set
Mitsui Memorial Hospital, Chiyoda-ku, Not set
Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital, Chuo-ku, Sapporo-shi, Not set
Sai Gastroenterologist Proctology, Fujiidera, Not set
Fukuoka University Hospital, Fukuoka, Not set
Matsuaikai Matsuda Hospital, Hamamatsu, Not set
Mito Medical Center, Higashiibaraki, Not set
National Hospital Organization Hirosaki National Hospital, Hirosaki, Not set
Sameshima Hospital, Kagoshima, Not set
Ofuna Central Hospital, Kamakura, Not set
Kawasaki Municipal Hospital, Kawasaki, Not set
Kitakyushu Municipal Medical Center, Kitakyusyu-shi, Not set
Aoyama Clinic GI Endoscopy & IBD Center, Kobe-shi, Not set
Showa University Koto Toyosu Hospital, Koto-ku, Not set
Kumagaya General Hospital, Kumagaya-shi, Not set
Hidaka Coloproctology Clinic, Kurume-shi, Not set
National Hospital Organization Kyoto Medical Center, Kyoto, Not set
Gunma University Hospital, Maebashi, Not set
Kitasato University Kitasato Institute Hospital, Minato-Ku, Not set
Kyorin University Hospital, Mitaka, Not set
Nagaoka Chuo General Hospital, Nagaoka, Not set
Hyogo College of Medicine, Nishinomiya, Not set
Ishida Clinic of IBD and Gastroenterology, Oita-shi, Not set
Okayama University Hospital, Okayama, Not set
Infusion Clinic, Osaka, Not set
National Hospital Organization - Osaka National Hospital - Institute For Clinical Research, Osaka, Not set
Saga-Ken Medical Center Koseikan, Saga, Not set
Tokitokai Tokito Clinic Coloproctology Center, Saitama, Not set
Toho University Sakura Medical Center, Sakura, Not set
Tokushukai Sapporo Tokushukai Hospital, Sapporo-shi, Not set
Sapporo Higashi Tokushukai Hospital, Sapporo, Not set
Takagi Clinic - Sendai, Sendai, Not set
Jichi Medical University Hospital, Shimotsuke, Not set
Center Hospital of the National Center for Global Health and Medicine, Shinjyuku-ku, Not set
Kagawa Prefectural Central Hospital, Takamatsu, Not set
National Hospital Organization Takasaki General Medical Centar, Takasaki, Not set
Tokyo Yamate Medical Center, Tokyo, Not set
Toyama Prefectural Central Hospital, Toyama, Not set
Mie University Hospital, Tsu, Not set
Matsushima Hospital, Yokohama, Not set
Yokohama City University Medical Center, Yokohama, Not set
Showa University Northern Yokohama Hospital, Yokohama, Not set
Dong-A University Hospital, Busan, Not set
The Catholic University of Korea, Daejeon St. Mary's Hospital, Daejeon, Not set
Yeungnam Univeristy Medical Center, Gyeongsan-si, Not set
Inje University Haeundae Paik Hospital, Haeundae-gu, Not set
Kyung Hee University Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
Kangbuk Samsung Hospital, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Yonsei University-Wonju Severance Christian Hospital, Wonju, Not set
Digestive Diseases Center "Gastro", Riga, Not set
Pauls Stradins Clinical Univeristy Hospital, Riga, Not set
RIGA EAST UNIVERSITY HOSPITAL ,Oncology Centre of Latvia, Riga, Not set
Hospital of Lithuanian University of Health Sciences Kaunas, Kaunas, Not set
Republic Hospital of Klaipeda, Klaipeda, Not set
Viesoji Istaiga Klaipedos Miesto Poliklinika, Klaipėda, Not set
Respublikine Panevezio ligonine, Panevezys, Not set
Vilnius University Hospital Santaros Klinikos, Vilnius, Not set
Hospital Sultanah Bahiyah, Alor Star, Not set
Pusat Perubatan University Kebangsaan Malaysia, Cheras, Kuala Lumpur, Not set
Hospital Raja Perempuan Zainab II, Kota Bahru, Not set
University Malaya Medical Centre, Kuala Lumpur, Not set
Hospital Universiti Sains Malaysia, Kubang Kerian, Not set
University Malaya Medical Centre, Lembah Pantai, Not set
Hospital Serdang, Selangor, Not set
Scientia Investigacion Clinica S.C., Chihuahua, Not set
Centro Para El Desarrollo de La Medicina Y de Asistencia Medica Especializada S.C., Culiacán, Not set
Sociedad de Metabolismo y Corazon, Veracruz, Not set
Republican Clinical Hospital, Chisinau, Not set
Amsterdam UMC, locatie VUmc, Amsterdam, Not set
Elisabeth-TweeSteden Ziekenhuis, Tilburg, Not set
Ziekenhuis Bernhoven, Uden, Not set
Universitair Medisch Centrum Utrecht, Utrecht, Not set
Promedica Dental Clinic, Bedzin, Not set
Centrum Medyczne "Medis" Manermed, Bydgoszcz, Not set
Centrum Medyczne Pratia Bydgoszcz, Bydgoszcz, Not set
Szpital Miejski im. Jana Pawła II w Elblagu, Elblag, Not set
All-Medicus, Katowice, Not set
Gabinet Endoskopii Przewodu Pokarmowego, Krakow, Not set
Topolowa Medicenter, Krakow, Not set
Samodzielny Publiczny Szpital Kliniczny nr 4 w Lublinie, Lublin, Not set
ZOZ Gastromed, Lublin, Not set
Medicenter Nowy Targ, Nowy Targ, Not set
Wojewódzki Szpital Specjalistyczny w Olsztynie, Olsztyn, Not set
Centrum Medyczne LUX MED - Rzeszow, Rzeszow, Not set
Endoskopia Sp. z.o.o., Sopot, Not set
Twoja Przychodnia - Szczecinskie Centrum Medyczne, Szczecin, Not set
SONOMED Centrum Medyczne, Szczecin, Not set
Gastromed, Torun, Not set
NZOZ Formed, Wadowice, Not set
Centralny Szpital Kliniczny MSWiA w Warszawie, Warsaw, Not set
Vivamed Sp. z o.o., Warsaw, Not set
WIP Warsaw IBD Point Profesor Kierkus, Warsaw, Not set
Centrum Zdrowia MDM, Warszawa, Not set
Planetmed, Wroclaw, Not set
LexMedica, Wroclaw, Not set
ETG Zamość, Zamosc, Not set
Spitalul de Oncologie Monza, Bucharest, Not set
S.C. Centrul Medical Medicum SRL, Bucuresti, Not set
Spitalul Clinic Colentina, Bucuresti, Not set
CCBR Clinical Research, Bucuresti, Not set
Spitalul Pelican, Oradea, Not set
Poliklinika Agmu "Konsul'tativno-Diagnosticheskiy Tsentr", Barnaul, Not set
LLC MA New Hospital, Ekaterinburg, Not set
Scientific Centre of Reconstructive and Restorative Surgery, Irkutsk, Not set
Alliance Biomedical URAL Group, Izhevsk, Not set
Kazan State Medical University, Kazan, Not set
SIH Kemerovo Regional Clinical Hosptial, Kemerovo, Not set
Nizhny Novgorod Regional Hospital N.A. Semashko, Nizhny Novgorod, Not set
Medical Center SibNovoMed, Novosibirsk, Not set
Research Institute of Physiology and Fundamental Medicine, Novosibirsk, Not set
Ultramed, Omsk, Not set
Karelia Republican Hospital V.A. Baranova, Petrozavodsk, Not set
Rostov State Medical University, Rostov-on-Don, Not set
North-Western State Medical University named after I.I.Mechnikov, Saint - Petersburg, Not set
City Mariinskaya Hospital, Saint Petersburg, Not set
Scientific research center ECO-security, Saint Petersburg, Not set
Saint Petersburg State Budgetary Healthcare Institution City Clinical Hospital No.31, Saint Petersburg, Not set
First Pavlov State Medical University of Saint Petersburg, Saint-Petersburg, Not set
Stavropol State Medical University, Stavropol, Not set
SHI of Yaroslavl Region Clinical Hospital #8, Yaroslavl, Not set
Clinical Hospital Center Zvezdara, Belgrade, Not set
University Medical Center "Bezanijska kosa", Belgrade, Not set
Clinical Center Kragujevac, Kragujevac, Not set
Regional Hospital Dr Radivoj Simonovic Sombor, Sombor, Not set
Sremska Mitrovica Health Centre, Sremska Mitrovica, Not set
General Hospital "Djordje Joanovic", Zrenjanin, Not set
Fakultna nemocnica s poliklinikou F.D.Roosevelta Banska Bystrica, Banska Bystrica, Not set
Cliniq s.r.o., Bratislava, Not set
KM Management, Nitra, Not set
Gastro, Prešov, Not set
Endomed, s.r.o., Vranov N. Toplou, Not set
Instituto de Ciencias Médicas, Alicante, Not set
Hospital Universitario de Fuenlabrada, Fuenlabrada, Not set
Hospital Universitari de Girona Doctor Josep Trueta, Girona, Not set
Hospital Universitario Juan Ramon Jimenez, Huelva, Not set
Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas De GC, Not set
Hospital Universitario La Paz, Madrid, Not set
Hospital Universitario Central de Asturias, Oviedo, Not set
Hospital de Sagunto y C.E., Sagunto, Not set
Hospital Universitario Marqués de Valdecilla, Santander, Not set
Inselspital Bern, Berne, Not set
Gastroenterologische Praxis Balsiger, Seibold & Partner, Bern, Not set
Cantonal Hospital St.Gallen, St.Gallen, Not set
UniversitätsSpital Zürich, Zürich, Not set
China Medical University Hospital, Taichung, Not set
National Taiwan University Hospital, Taipei, Not set
Antalya Egitim ve Arastırma Hastanesi, Antalya, Not set
Ege University Medicine of Faculty, Bornova, Not set
Kocaeli Üniversitesi, Kocaeli, Not set
Mersin University, Mersin, Not set
Communal non-profit enterprise "Regional clinical hospital of Ivano-Frankivsk Regional Council", Ivano-Frankivsk, Not set
City Clinical Hospital No. 2, Kharkiv, Not set
L.T. Mala National Institute of Therapy of NAMS of Ukraine, Kharkiv, Not set
Kherson City Clinical Hospital, Kherson, Not set
Medical Center of Limited Liability Company "Medical Center "Consilium Medical", Kiev, Not set
Private Enterprise Private Manufacturing Company Acinus, Kropyvnytskyi, Not set
Municipal Nonprofit Enterprise of Kyiv Region Council "Kyiv Regional Clinical Hospital", Kyiv, Not set
Medical Center Ok!Clinic+, Kyiv, Not set
Municipal non-profit enterprise of Kyiv Regional Council "Kyiv Regional Center for Rehabilitation Medicine", Kyiv, Not set
Lviv Railway Clinical Hospital, Lviv, Not set
Municipal non-profit enterprise "Lviv Territorial Medical Union "Multidisciplinary Clinical Hospital of Em -T, Lviv, Not set
Lviv Regional Clinical Hospital - Lviv National Medical University named Danylo Galician, Lviv, Not set
Municipal non-profit enterprise'Odesa Regional Clinical Hospital'of Odesa Regional Council, Odesa, Not set
Poltova Oblast Clinical Hospital IM.M.V.Sklifosovskoho, Poltava, Not set
Transcarpathian Regional Hospital im.Andriya Novak, Uzhgorod, Not set
Medical Clinical Investigational Center of Medical Center Health Clinic, Vinnytsia, Not set
City Clinical Hospital #1, Vinnitsya National Medical University, Vinnytsya, Not set
VNMU, Vinnytsya, Not set
Diaservis - Medical and Diagnostic Center, Zaporizhia, Not set
Diacenter, Zaporizhzhia, Not set
Fairfield General Hospital, Bury, Not set
Barts Health NHS Trust, London, Not set
Guy's & St Thomas' NHS Foundation Trust, London, Not set
The John Radcliffe Hospital, Oxford, Not set
Conditions: Ulcerative Colitis
Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study
Recruiting
TAPISTRY is a Phase II, global, multicenter, open-label, multi-cohort study designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or in rational, specified combinations in participants with unresectable, locally advanced or metastatic solid tumors determined to harbor specific oncogenic genomic alterations or who are tumor mutational burden (TMB)-high as identified by a validated next-generation sequencing (NGS) assay. Participants with solid tumors... Read More
TAPISTRY is a Phase II, global, multicenter, open-label, multi-cohort study designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or in rational, specified combinations in participants with unresectable, locally advanced or metastatic solid tumors determined to harbor specific oncogenic genomic alterations or who are tumor mutational burden (TMB)-high as identified by a validated next-generation sequencing (NGS) assay. Participants with solid tumors will be treated with a drug or drug regimen tailored to their NGS assay results at screening. Participants will be assigned to the appropriate cohort based on their genetic alteration(s). Treatment will be assigned on the basis of relevant oncogenotype, will have cohort-specific inclusion/exclusion criteria, and, unless otherwise specified, will continue until disease progression, loss of clinical benefit, unacceptable toxicity, participant or physician decision to discontinue, or death, whichever occurs first. Read Less
Gender:
ALL
Ages:
All
Trial Updated:
08/22/2025
Locations: Southern Cancer Center, Daphne, Alabama +162 locations
Southern Cancer Center, Daphne, Alabama
Western Regional Medical Center at Cancer Treatment Centers of America, Goodyear, Arizona
City of Hope National Medical Center, Duarte, California
Kaiser Permanente Los Angeles, Los Angeles, California
USC Norris Cancer Center, Los Angeles, California
Hoag Memorial Hospital, Newport Beach, California
UC Davis Comprehensive Cancer Center, Sacramento, California
University of California at San Francisco, San Francisco, California
Sarcoma Oncology Center, Santa Monica, California
Children's Hospital Colorado, Aurora, Colorado
Christiana Care Health Srvcs, Newark, Delaware
University of Florida, Gainesville, Florida
Miami Cancer Institute of Baptist Health, Inc., Miami, Florida
Ocala Oncology Center, Ocala, Florida
University Cancer & Blood Center, LLC, Athens, Georgia
St. Alphonsus, Boise, Idaho
Midwestern Regional Med Center, Zion, Illinois
Horizon Oncology Research, Inc., Lafayette, Indiana
New England Cancer Specialists, Scarborough, Maine
Maryland Hematology & Oncology. P.A., Silver Spring, Maryland
St. Joseph Mercy Hospital, Ann Arbor, Michigan
Henry Ford Health System, Detroit, Michigan
University of Minnesota, Minneapolis, Minnesota
Metro-Minnesota Community Oncology Research Consortium, Saint Louis Park, Minnesota
Washington University, Saint Louis, Missouri
Intermountain Health St. Vincent Regional Hospital - Cancer Centers of Montana, Billings, Montana
Nebraska Methodist Hospital, Omaha, Nebraska
Comprehensive Cancer Centers of Nevada - Eastern Avenue, Las Vegas, Nevada
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
University of New Mexico, Albuquerque, New Mexico
Montefiore Einstein Center for Cancer Care, Bronx, New York
Eastchester Center for Cancer Care, Bronx, New York
National Translational Research Group, New York, New York
Icahn School of Medicine at Mount Sinai, New York, New York
Memorial Sloan Kettering Cancer Center, New York, New York
New York Cancer and Blood Specialists - Setauket Medical Oncology, Port Jefferson Station, New York
Barrett Cancer Center, Cincinnati, Ohio
Oncology Hematology Care Inc, Cincinnati, Ohio
Providence Portland Medical Center, Portland, Oregon
Consultants in Medical Oncology and Hematology, Broomall, Pennsylvania
Alliance Cancer Specialists, Horsham, Pennsylvania
Virginia Cancer Specialists - Leesburg, Leesburg, Pennsylvania
Cancer Treatment Centers of America, Philadelphia, Pennsylvania
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
PRISMA Health - Greenville, Greenville, South Carolina
The West Clinic, Germantown, Tennessee
St. Jude Children'S Research Hospital, Memphis, Tennessee
Texas Oncology - Central South, Austin, Texas
Mary Crowley Medical Research Center, Dallas, Texas
Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas, Texas
Cook Childrens Medical Center, Fort Worth, Texas
The University of Texas MD Anderson Cancer Center, Houston, Texas
Texas Oncology- Northeast Texas, Tyler, Texas
Northwest Medical Specialties, PLLC, Tacoma, Washington
Froedtert and The Medical College of Wisconsin, Milwaukee, Wisconsin
Kinghorn Cancer Centre, Darlinghurst, New South Wales
Sydney Children's Hospital, Randwick, New South Wales
Royal Darwin Hospital, Tiwi, Northern Territory
Princess Alexandra Hospital, Woolloongabba, Queensland
Peter MacCallum Cancer Centre, Melbourne, Victoria
Royal Children's Hospital, Parkville, Victoria
Cliniques Universitaires St-Luc, Bruxelles, Not set
GHdC Site Les Viviers, Charleroi, Not set
UZ Antwerpen, Edegem, Not set
UZ Gent, Gent, Not set
UZ Leuven Gasthuisberg, Leuven, Not set
Hospital Moinhos de Vento, Porto Alegre, Rio Grande Do Sul
Hospital Sírio-Libanês, Sao Paulo, São Paulo
Hospital Sírio-Libanês, Sao Paulo, São Paulo
Hospital A. C. Camargo, Sao Paulo, São Paulo
Clínica Onco Star - Rede D'Or, Sao Paulo, São Paulo
BC Cancer ? Vancouver, Vancouver, British Columbia
London Health Sciences Centre · Victoria Hospital, London, Ontario
The Ottawa Hospital - General Campus, Ottawa, Ontario
The Hospital for Sick Children, Toronto, Ontario
Princess Margaret Cancer Center, Toronto, Ontario
McGill University Health Center, Montreal, Quebec
Beijing Cancer Hospital, Beijing, Not set
Beijing Children's Hospital, Capital Medical University, Beijing, Not set
The First Hospital of Jilin University, Changchun City, Not set
Jilin Cancer Hospital, Changchun, Not set
West China Hospital - Sichuan University, Chengdu City, Not set
Shanghai East Hospital, Shanghai City, Not set
Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Not set
Zhongshan Hospital Fudan Unvierstiy, Shanghai, Not set
Tianjin Cancer Hospital, Tianjin, Not set
First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Not set
Aarhus Universitetshospital, Aarhus N, Not set
Rigshospitalet, København Ø, Not set
Institut Bergonie, Bordeaux, Not set
Centre Oscar Lambret, Lille, Not set
Centre Leon Berard, Lyon, Not set
Hopital de la Timone, Marseille, Not set
Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, Not set
Institut de Cancerologie Gustave-Roussy (IGR), Villejuif, Not set
Uniklinik Essen, Essen, Not set
Georg-August-Uniklinik, Göttingen, Not set
Universitätsklinikum Hamburg-Eppendorf Onkologisches Zentrum Medizinische Klinik II, Hamburg, Not set
Medizinische Hochschule Zentrum Innere Medizin Abt.Gastroenterologie, Endokrinologie und Hepatologie, Hannover, Not set
SLK-Kliniken Heilbronn GmbH;Klinik für Innere Medizin III, Heilbronn, Not set
Praxis für Hämatologie, Onkologie und Palliativmedizin, Mönchengladbach, Not set
Klinikum der Universität München, Campus Großhadern, München, Not set
Universtitätsklinikum Ulm, Ulm, Not set
Uniklinikum, Comprehensive Cancer Center Mainfranken, Würzburg, Not set
Hong Kong Children's Hospital, Hong Kong, Not set
Prince of Wales Hospital, Shatin, Not set
Rambam Health Care Campus, Haifa, Not set
Hadassah University Hospital - Ein Kerem, Jerusalem, Not set
Rabin MC, Petach Tikva, Not set
Sheba Medical Center, Ramat Gan, Not set
Sourasky / Ichilov Hospital, Tel Aviv, Not set
Istituto Nazionale Tumori Fondazione G. Pascale, Napoli, Campania
Ospedale Pediatrico Bambino Gesù - IRCCS, Roma, Lazio
Policlinico Universitario Agostino Gemelli IRCCS, Roma, Lazio
Asst Degli Spedali Civili Di Brescia, Brescia, Lombardia
Irccs Istituto Nazionale Dei Tumori (Int), Milano, Lombardia
Istituto Nazionale Tumori di Milano, Milano, Lombardia
Dipartimento di Scienze Pediatriche Adolescenza, Torino, Piemonte
Azienda Ospedaliera Meyer, Firenze, Toscana
Azienda Ospedaliera Universitaria Senese, U.O.C. Immunoterapia Oncologica, Siena, Toscana
National Cancer Center Hospital East, Chiba, Not set
Kindai University Hospital, Osaka, Not set
National Cancer Center Hospital, Tokyo, Not set
Seoul National University Bundang Hospital, Gyeonggi-do, Not set
Seoul National University Hospital- Adult Site, Seoul, Not set
Seoul National University Hospital- Pediatric Site, Seoul, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center- Adult Site, Seoul, Not set
Samsung Medical Center- Pediatric Site, Seoul, Not set
Auckland City Hospital, Cancer and Blood Research, Auckland, Not set
Uniwersyteckie Centrum Kliniczne, Klinika Onkologii i Radioterapii, Gda?sk, Not set
Narod.Inst.Onkol. im. M.Sklodowskiej - Curie-Panst.Inst.Bad, Warszawa, Not set
IPO do Porto, Porto, Not set
PanOncology Trials, San Juan, Not set
National University Hospital, Singapore, Not set
National Cancer Centre, Singapore, Not set
Medical Oncology Centre of Rosebank, Johannesburg, Not set
Hospital Sant Joan De Deu, Esplugues De Llobregas, Barcelona
Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Barcelona, Not set
Vall d?Hebron Institute of Oncology (VHIO), Barcelona, Barcelona, Not set
Hospital Infantil Universitario Nino Jesus, Madrid, Not set
Clinica Universidad de Navarra Madrid, Madrid, Not set
START Madrid-FJD, Hospital Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
START Madrid. Centro Integral Oncologico Clara Campal, Madrid, Not set
Hospital Universitario la Fe, Valencia, Not set
Universitätsspital Basel (USB), Basel, Not set
Ospedale Regionale di Bellinzona Medizin Onkologie, Bellinzona, Not set
Inselspital, Klinik und Poliklinik für Medizinische Onkologie, Bern, Not set
Unversitätsspital Zürich, Zürich, Not set
Taichung Veterans General Hospital, Taichung, Not set
National Cheng Kung University Hospital, Tainan, Not set
Taipei Veterans General Hospital, Taipei City, Not set
Chang Gung Memorial Hospital-Linkou, Taoyuan County, Not set
National Taiwan University Hospital, Zhongzheng Dist., Not set
Beatson West of Scotland Cancer Centre, Glasgow, Not set
University College London Hospital, London, Not set
Guys and St Thomas NHS Foundation Trust, Guys Hospital, London, Not set
Royal Manchester Children?s Hospital, Manchester, Not set
The Christie NHS Foundation Trust, Manchester, Not set
Conditions: Solid Tumors
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
Recruiting
The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical insights, treatment patterns, and factors driving the treatment decisions among patients being treated with specified Roche ophthalmology products in approved retinal indications (Faricimab for neovascular age-related macular degeneration \[nAMD\], diabetic macular edema \[DME\]... Read More
The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical insights, treatment patterns, and factors driving the treatment decisions among patients being treated with specified Roche ophthalmology products in approved retinal indications (Faricimab for neovascular age-related macular degeneration \[nAMD\], diabetic macular edema \[DME\], and retinal vein occlusion; Port Delivery System with Ranibizumab for nAMD) in routine clinical practice. This study will not provide or make recommendations on use of any products including Roche products; treatment decisions will be determined by the treating physician and must be made independently to the decision to participate in this study. Participation in this study will not change or influence a patient's standard of care in any way. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2025
Locations: Retinal Research Institute, LLC, Phoenix, Arizona +308 locations
Retinal Research Institute, LLC, Phoenix, Arizona
Retina-Vitreous Associates Medical Group, Beverly Hills, California
California Eye Specialists Medical group Inc., Pasadena, California
Retinal Consultants Medical Group, Sacramento, California
Advanced Research, Coral Springs, Florida
Retina Specialty Institute, Pensacola, Florida
University Retina and Macula Associates, PC, Lemont, Illinois
Springfield Clinic, Llp, Springfield, Illinois
Retina Associates of Kentucky, Lexington, Kentucky
Cumberland Valley Retina Consultants PC, Hagerstown, Maryland
Associated Retinal Consultants PC, Royal Oak, Michigan
Erie Retinal Surgery, Erie, Pennsylvania
Palmetto Retina Center, Florence, South Carolina
Tennessee Retina PC, Nashville, Tennessee
Brown Retina Institute, San Antonio, Texas
Retina Center of Texas, Southlake, Texas
University of Utah, John Moran Eye Center, Salt Lake City, Utah
Piedmont Eye Center, Lynchburg, Virginia
Wagner Macula and Retina Center, Norfolk, Virginia
Spokane Eye Clinical Research, Spokane, Washington
Salud Ocular, Ciudad Autonoma de Buenos Aires, Buenos Aires
Centro Oftalmologico Dr. Charles S.A., Ciudad Autonoma Buenos Aires, Not set
Instituto Oftalmologico de Buenos Aires S.A., Ciudad Autonoma de Buenos Aires, Not set
Centro Privado de Ojos Romagosa S.A, Cordoba, Not set
CEO Centro de Especialidades Oftalmologicas Tucuman, San Miguel de Tucuman, Not set
Retina and Macula Specialists, Hurstville, New South Wales
Sydney West Retina, Westmead, New South Wales
Sunshine Coast University Hospital, Geebung, Queensland
Centre For Eye Research Australia, East Melbourne, Victoria
East Melbourne Eye Group, East Melbourne, Victoria
Cabrini Hospital Malvern, Melbourne, Victoria
Retina Specialists Victoria, Rowville, Victoria
Lions Outback Vision Service in Broome, Broome, Western Australia
The Lions Eye Institute, Nedlands, Western Australia
Medical Center for Eye Health ? Focus Ltd, Sofia, Not set
Specialized Eye Hospital Pentagram, Sofia, Not set
Specialized Hospital for Active Treatment of Ophthalmologic Diseases ?Zora?, OOD, Sofia, Not set
Eye Clinic St. Petka - Varna, Varna, Not set
SHEDAT - Varna EOOD, Varna, Not set
Retina Surgical Associates, New Westminster, British Columbia
Toronto Retina Institute, Don Mills, Ontario
St Joseph's Centre for Mountain Health Services, Hamilton, Ontario
St. Joseph's Health Care - London, London, Ontario
Retina Institute of Ottawa, Ottawa, Ontario
Clarity eye Institute, Vaughan, Ontario
Institut De L'Oeil Des Laurentides, Boisbriand, Quebec
Clinique d'ophtalmologie et de Retine de l'est, Montreal, Quebec
Eye Health MD (Opthalmology), Montreal, Quebec
Retina MD Clinic, Sainte-catherine, Quebec
Centre Oculaire de Quebec, Quebec, Not set
Centro de la Vision, Las Condes, Not set
Red Salud UC Christus, Metropolitana, Not set
Clinica Oftalmologica Pasteur, Santiago, Not set
Fundacion Oftalmologica Los Andes, Vitacura, Not set
General Hospital Karlovac, Karlovac, Not set
Clinical Hospital Centre Osijek, Osijek, Not set
Clinical Hospital Centre Rijeka, Rijeka, Not set
Special Hospital for Ophthalmology Svjetlost, Zagreb, Not set
University Hospital Center Zagreb, Zagreb, Not set
Nemocnice Ceske Budejovice a.s., Ceske Budejovice, Not set
Nemocnice Pardubickeho kraje a.s., Pardubice, Not set
Fakultni nemocnice Kralovske Vinohrady, Praha, Not set
Tomas Bata Regional Hospital, Zlín, Not set
Ålborg Universitets Hospital, Aalborg, Not set
Rigshospitalet Glostrup, Glostrup, Not set
Sjllands Universitetshospital, Roskilde, Not set
Egypt Air Hospital, Cairo, Not set
CH St Joseph, Marseille, Bouches Du Rh(ne
CHU Dijon - Hopital Francois Mitterrand, Dijon Cedex, Cte-d'Or
Groupe Hospitalier Pellegrin, Bordeaux, Gironde
CHU de Nantes - Hotel Dieu, Nantes Cedex 1, Loire Atlantique
CHU de St-Etienne - Hopital Nord, Saint Etienne, Loire
Institut Ophtalmologique De l Ouest Jules Verne, Nantes, Paris
Centre Hospitalier de la Croix Rousse, Lyon Cedex 04, Rhone
Hopital Edouard Herriot - CHU Lyon, Lyon, Rhone
Clinique Mathilde, Rouen, Seine Maritime
CHU Amiens Picardie, Centre de Recherche Clinique, Amiens Cedex 01, Somme
Centre Hospitalier de Versailles, Le Chesnay Cedex, Yvelines
Aix Vision, Aix En Provence, Not set
Hopital Avicenne, Bobigny, Not set
Clinique des Yeux Bordeaux, Bordeaux Floirac, Not set
Centre Rétine Gallien, Bordeaux, Not set
Centre Hospitalier Intercommunal de Créteil, Creteil cedex, Not set
Clinique du Val d'Ouest- Institut Rhône Alpin, Ecully, Not set
Centre d'Ophtalmologie, Fontainebleau, Not set
Centre Optha Du Dauphine, Grenoble, Not set
Hôpital Saint-Louis - La Rochelle, La Rochelle cedex, Not set
Visiopole Private Practice, Lagord, Not set
Centre Ophtalmologique Rabelais, Lyon, Not set
Centre Ophtalmologique Kleber, Lyon, Not set
Centre Monticelli Paradis d Ophtalmologie, Marseille, Not set
Clinique de Montargis, Montargis, Not set
Clinique Honore Cave, Montauban, Not set
Alpes Retine, Montbonnot-Saint-Martin, Not set
Centre Des Arceaux, Montpellier, Not set
CHU Nice - Hôpital Saint Roch, Nice, Not set
OPH95, Osny, Not set
Centre Ophtalmologique de L'Odeon, Paris, Not set
Centre Ophtalmologique d?Imagerie et de Laser, Paris, Not set
Hospital Foundation Adolphe De Rothschild, Paris, Not set
CHU Poitiers - Hôpital la Milétrie, Poities Cedex, Not set
Clinique de l'Union, Saint-jean, Not set
Centre St Exupery, St Cyr Sur Loire, Not set
Institut Sourdille, St Herblain, Not set
Chu Toulouse, Toulouse, Not set
Augenzentrum Prof. Koch GmbH, Frankfurt am Main, Hessen
Universitaetsklinikum Koeln, Koeln, Nordrhein Westfalen
Apotheke am Klinikum Ludwigshafen, Ludwigshafen, Rheinland Pfalz
Universitaetsklinikum Magdeburg A.oe.R, Magdeburg, Sachsen Anhalt
Universitaetsklinikum Carl Gustav Carus TU Dresden, Dresden, Sachsen
St. Gertrauden Krankenhaus Berlin, Augenheilkunde, Berlin, Not set
Vivantes Klinikum Neukoelln, Berlin, Not set
Charité Universitätsmedizin Berlin, Berlin, Not set
Klinikum Chemnitz gGmbH, Chemnitz, Not set
Martin-Luther-Universitaet Halle-Wittenberg - Staedtisches Klinikum Dessau (SKD), Dessau - Roßlau, Not set
Universitaetsklinikum Frankfurt Goethe-Universitaet, Frankfurt, Not set
Universitaetsmedizin Greifswald, Greifswald, Not set
Universitaetsklinikum Halle (Saale), Halle, Not set
Medizinische Hochschule Hannover, Hannover, Not set
Universitaetsklinikum Heidelberg, Heidelberg, Not set
Universitaetsklinikum Leipzig, Leipzig, Not set
Universitaetsklinikum Schleswig-Holstein - Campus Luebeck, Lübeck, Not set
Universitätsklinikum Mannheim, Mannheim, Not set
Praxis Dr. Amin Gamael, Rostock, Not set
Universitaetsaugenklinik Rostock, Rostock, Not set
Knappschaftskrankenhaus Sulzbach, Sulzbach, Not set
Medical Eye Research Xpertx Institut gGmbH, Trier, Not set
Private Practice of Dr. Astrid Sader Moritz, Würzburg, Not set
Augenzentrum Erzgebirge, Zschopau, Not set
Grantham Hospital, Hong Kong, Not set
Hong Kong Eye Hospital, Kowloon, Not set
Rambam Health Care Campus, Haifa, Not set
Wolfson Medical Center, Holon, Not set
Hadassah, Jerusalem, Not set
Meir Medical Center, Kfar- Saba, Not set
Rabin MC, Petah Tikva, Not set
Kaplan Medical Center, Rehovot, Not set
Assuta Hashalom Medical Center, Tel Aviv-Yafo, Not set
Tel-Aviv Sourasky Medical Center, Tel Aviv, Not set
Ospedale Clinicizzato SS. Annunziata, Chieti, Abruzzo
Azienda Ospedaliero Universitaria Mater Domini, Catanzaro, Calabria
Ospedale Monaldi - AORN dei Colli, Napoli, Campania
Azienda Ospedaliera di Udine Ospedale S. Maria della Misericordia, Udine, Friuli-Venezia Giulia
Fondazione Ptv Policlinico Tor Vergata, Roma, Lazio
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Lazio
G. B. Bietti Fondazione - IRCCS, Roma, Lazio
Azienda Ospedaliera Sant'Andrea-Universitr di Roma La Sapien, Roma, Lazio
IRCCS Ospedale Policlinico San Martino, Genova, Liguria
Humanitas Gavazzeni, Bergamo, Lombardia
Fondazione IRCCS CA? Granda Ospedale Maggiore Policlinico, Milano, Lombardia
Ospedale San Raffaele, Milano, Lombardia
Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo (San Paolo-Polo Universitario), Milano, Lombardia
Azienda Socio Sanitaria Territoriale Fatebenefratelli (Presidio Ospedale Sacco), Milano, Lombardia
Ospedale San Giuseppe Fatebenefratelli, Milan, Lombardia
Azienda Ospedaliera Desio, Vimercate, Lombardia
Azienda Ospedaliero Universitaria delle Marche, Ancona, Marche
Ente Ecclesiastico Ospedale Generale Regionale F Miulli, Acquaviva Delle Fonti, Piemonte
Ospedale Oftalmico, Torino, Piemonte
Città della Salute e della Scienza di Torino. Presidio Molinette, Torino, Piemonte
Ospedale Mauriziano Umberto I, Torino, Piemonte
Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari, Bari, Puglia
Università di Cagliari-Presidio Ospedaliero S. Giovanni di Dio, Cagliari, Sardegna
Ospedale Di Sassuolo, Sassuolo, Sardegna
Azienda Ospedaliera Universitaria "Policlinico - Vittorio Emanuele" (Presidio Gaspare Rodolico), Catania, Sicilia
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone, Palermo, Sicilia
Aichi Medical University Hospital, Nagakute-shi, Aichi-Ken
Nagoya University Hospital, Nagoya-shi, Aichi-Ken
Toho University Sakura Medical Center, Sakura-shi, Chiba-Ken
Hokkaido University Hospital, Sapporo-shi, Hokkaido
Kobe University Hospital, Kobe-shi, Hyogo-Ken
Yokohama City University Medical Center, Yokohama-shi, Kanagawa-Ken
Jichi Medical University Hospital, Shimotsuke-shi, Tochigi-Ken
Nihon University Hospital, Chiyoda-ku, Tokyo-To
Tokyo Medical University Hospital, Shinjuku-ku, Tokyo-To
Keio University Hospital, Shinjuku-ku, Tokyo-To
Chukyo Hospital, Aichi, Not set
Sugita Eye Hospital, Aichi, Not set
Nagoya City University Hospital, Aichi, Not set
Akita University Hospital, Akita-shi, Not set
Chiba University Hospital, Chiba, Not set
Juntendo University Urayasu Hospital, Chiba, Not set
University of Yamanashi Hospital, Chuo-shi, Not set
Kyushu University Hospital, Fukuoka, Not set
Kurume University Hospital, Fukuoka, Not set
Gifu University Hospital, Gifu-shi, Not set
Hiroshima University Hospital, Hiroshima, Not set
Sapporo City General Hospital, Hokkaido, Not set
University of Tsukuba Hospital, Ibaraki, Not set
Kozawa eye hospital and diabetes center, Ibaraki, Not set
Kagawa University Hospital, Kagawa, Not set
NHO Tokyo Medical Center, Meguro-ku, Not set
Mie University Hospital, Mie, Not set
Fukushima Medical University Hospital, Miyagi, Not set
Shinshu University Hospital, Nagano, Not set
Nagasaki University Hospital, Nagasaki, Not set
Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Not set
Tazuke-kofukai Medical Research Institute Kitano Hospital, Osaka-shi, Not set
Osaka Metropolitan University Hospital, Osaka, Not set
Kansai Medical University Hospital, Osaka, Not set
Saitama Medical University Hospital, Saitama, Not set
Shiga University Of Medical Science Hospital, Shiga, Not set
Seirei Hamamatsu General Hospital, Shizuoka, Not set
Osaka University Hospital, Suita, Not set
Osaka Medical and Pharmaceutical University Hospital, Takatsuki-shi, Not set
Tokushima University Hospital, Tokushima, Not set
Juntendo University Hospital, Tokyo, Not set
Tokyo Women's Medical University Hospital, Tokyo, Not set
Kyorin University Hospital, Tokyo, Not set
Tokyo Medical University Hachioji Medical Center, Tokyo, Not set
Fujita Health University Hospital, Toyoake-shi, Not set
Yamagata University Hospital, Yamagata, Not set
Yamaguchi University Hospital, Yamaguchi, Not set
University of Fukui Hospital, Yoshida-gun, Not set
CHA Bundang Medical Center, CHA University, Seongnam-si, Gyeonggi-do
Yeungnam University Hospital, Daegu, Not set
Centrum Diagnostyki i Mikrochirurgii Oka LENS, Olsztyn, Not set
Szpital im. Jozefa Strusia, Pozna?, Not set
Szpital Specjalistyczny im Soko?owskiego, Wa?brzych, Not set
Wojskowy Instytut Medyczny - Panstwowy Instytut Badawczy, Warszawa, Not set
Emanuelli Research and Development Center, Arecibo, Not set
King Khalid Eye Specialist Hospital, Ar Riyadh, Not set
National University Hospital, Singapore, Not set
Singapore National Eye Centre, Singapore, Not set
Eye & Retina Surgeons, Singapore, Not set
Tan Tock Seng Hospital, Singapore, Not set
Eagle Eye Centre, Singapore, Not set
Univerzitetni Klinicni Center Ljubljana Ocesna Klinika, Ljubljana, Not set
Fundacio Privada Hospital Asil de Granollers, Granollers, Barcelona
Hospital Universitari de Bellvitge, L' Hospitalet DE Llobregat, Barcelona
Hospital Universitari Son Espases, Palma de Mallorca, Islas Baleares
Complejo Hospitalario Universitario de Ferrol, Ferrol, LA Coruna
Complejo Hospitalario Universitario de Santiago., Santiago de Compostela, LA Coruna
Complejo Hospitalario San Millán y San Pedro De La Rioja, Logroño, LA Rioja
Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, LAS Palmas
Hospital Costa del Sol, Marbella, Malaga
Hospital Xeral-Cies de Vigo, Vigo, Pontevedra
Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Tenerife
Hospital de Basurto, Bilbao, Vizcaya
Complejo Hospitalario Universitario de Albacete, Albacete, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Hospital Dos de Maig, Barcelona, Not set
Hospital Universitari Vall dHebron (CEMCAT), Barcelona, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
Complejo Asistencial Universitario de Burgos, Burgos, Not set
Hospital Universitario Puerta del Mar, Cadiz, Not set
Hospital Universitario Reina Sofia, Cordoba, Not set
Hospital Universitario Virgen de Las Nieves, Granada, Not set
Hospital Carlos Haya, Malaga, Not set
Hospital Universitario Virgen de La Arrixaca, Murcia, Not set
Hospital Universitario Virgen Del Rocio Sevila, Sevilla, Not set
Hospital Universitario Rio Hortega, Valladolid, Not set
Hospital Universitario Miguel Servet, Zaragoza, Not set
Lund University Hospital, Lund, Not set
St Eriks Eye Hospital, Stockholm, Not set
Kantonsspital Aarau AG, Aarau, Not set
Universitätsspital Basel, Basel, Not set
Augenklinik am Lindenhofspital, Bern, Not set
Inselspital-Universitaetsspital Bern, Bern, Not set
Vista Augenklinik Binningen, Binningen, Not set
Hôpitaux Universitaires de Genève, Geneve, Not set
Hôpital ophtalmique Jules-Gonin, Lausanne, Not set
Swiss Visio Montchoisi, Lausanne, Not set
Ospedale Regionale di Lugano, Lugano, Not set
LUKS Spitalbetriebe AG, Luzern 16, Not set
Pallas Klinik Olten, Olten, Not set
Kantonsspital St. Gallen, St. Gallen, Not set
Stadtspital Triemli, Zürich, Not set
Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Not set
Far Eastern Memorial Hospital, Taipei, Not set
Chang Gung Memorial Hospital - Linkou, Taoyuan, Not set
King Chulalongkorn Memorial Hospital, Pathum Wan, Bangkok
Songklanagarind Hospital, Hat Yai, Songkhla
Ramathibodi Hospital, Bangkok, Not set
Siriraj Hospital, Bangkok, Not set
Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Not set
Khon Kaen Hospital, Khon Kaen, Not set
Metta Pracharak Hospital, RAI Khing, Not set
Burjeel Hopital, Abu dhabi, Not set
Magrabi Eye Hospital, Dubai Healthcare City, Not set
Medcare Eye Center - Dubai, Dubai, Not set
Bristol Eye Hospital, Bristol, Avon
Bedford Hospital, Bedford, Bedfordshire
Torbay Hospital, Torquay, Devon
Hull Royal Infirmary, Hull, East Riding Of Yorkshire
Primary Care Centre, Colchester, Essex
Gloucestershire Retinal Research Group, Gloucester, Gloucestershire
Kings College Hospital, London, Greater London
Royal Liverpool University Hospital, Liverpool, Merseyside
James Paget University Hospitals NHS Foundation Trust, Gorleston, Norfolk
Mater Infirmorum Hospital, Belfast, Not set
University Hospitals Birmingham NHS Foundation Trust, Birmingham, Not set
Birmingham Midland Eye Centre, Birmingham, Not set
Bradford Royal Infirmary, Bradford, Not set
University Hospital of Wales, Cardiff, Not set
University Hospitals Coventry and Warwickshire NHS Trust, Coventry, Not set
Frimley Park Hospital, Frimley, Not set
North West London Hospitals NHS Trust, Harrow, Not set
St James University Hospital, Leeds, Not set
Moorfields Eye Hospital, London, Not set
Royal Free Hospital, London, Not set
Maidstone Hospital, Maidstone, Kent, Not set
Manchester Royal Eye Hospital, Manchester, Not set
James Cook University Hospital, Middlesbrough, Not set
Royal Victoria Infirmary, Newcastle upon Tyne, Not set
John Radcliffe Hospital, Oxford, Not set
Royal Hallamshire Hospital, Sheffield, Not set
Southampton General Hospital, Southampton, Not set
Sunderland Eye Infirmary, Sunderland, Not set
The Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, Not set
Conditions: Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion, Branch Retinal Vein Occlusion, Central Retinal Vein Occlusion, Hemi-retinal Vein Occlusion
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