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Semaglutide Treatment Options in Canada
A collection of 85 research studies where Semaglutide is the interventional treatment. These studies are located in the Canada . Semaglutide is used for conditions such as Diabetes Mellitus, Type 2, Obesity and Diabetes.
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Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee Osteoarthritis
Completed
This study will look at participants body weight from the start to the end of the study. It will also look at how much pain participants have in participants knee from the start to the end of the study and how this affects participants daily life. This is to compare the effect on body weight and pain in the knee in people taking semaglutide with people taking "dummy" medicine. Participants will either get semaglutide or "dummy" medicine. Which treatment participants get is decided by chance.
Pa... Read More
This study will look at participants body weight from the start to the end of the study. It will also look at how much pain participants have in participants knee from the start to the end of the study and how this affects participants daily life. This is to compare the effect on body weight and pain in the knee in people taking semaglutide with people taking "dummy" medicine. Participants will either get semaglutide or "dummy" medicine. Which treatment participants get is decided by chance.
Participants will need to take 1 injection once a week. The study medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm. During the study, participants will have talks with study staff about how to eat healthy food and how to be more physically active. The study will last for about 1 ½ years. Participants will have 14 clinic visits with the study staff. At the first clinic visit participants will have a blood sample taken. Participants will have an X-ray of participants knee taken at the first visit. If participants have had an X-ray recently, this may not be needed.
At 6 of the clinic visits participants cannot take pain medications for 3 days before the visit. Participants cannot take part if participants have had a joint replacement surgery in participants knee. Participants cannot take part if participants have or have had diabetes. Women: Women cannot take part if pregnant, breast-feeding or plan to become pregnant during the study period. Read Less
Gender:
ALL
Ages:
All
Trial Updated:
07/09/2025
Locations: Baptist Health System, Montgomery, Alabama +65 locations
Baptist Health System, Montgomery, Alabama
Desert Oasis Hlthcr Med Group, Palm Springs, California
Diablo Clinical Research, Inc., Walnut Creek, California
Westside Center For Clinical Research, Jacksonville, Florida
Renstar Medical Research, Ocala, Florida
East West Medical Research Institute, Honolulu, Hawaii
Clinical Invest Special_Gurnee, Gurnee, Illinois
Evanston Premier Hlthcr Res, Skokie, Illinois
L-MARC Research Center, Louisville, Kentucky
Arcturus Healthcare, PLC., Troy, Michigan
Sundance Clinical Research LLC, Saint Louis, Missouri
Southgate Medical Group, LLP, West Seneca, New York
Great Lakes Medical Research, Westfield, New York
Accellacare, Wilmington, North Carolina
Cleveland Clinic_Cleveland, Cleveland, Ohio
Prestige Clinical Research, Franklin, Ohio
Coastal Carolina Res Ctr., North Charleston, South Carolina
PrimeCare Medical Group, Houston, Texas
Health Res of Hampton Roads, Newport News, Virginia
Ocean West Research Clinic, Surrey, British Columbia
Wharton Med Clin Trials, Hamilton, Ontario
Premier Clinical Trial Research Network (PCTRN), Hamilton, Ontario
Milestone Research, London, Ontario
Dr. Anil K Gupta Medicine Professional Corporation, Toronto, Ontario
Centre Medical Acadie, Montreal, Quebec
Centro de investigación médico asistencial S.A.S, Barranquilla, Not set
CentrodeInvestigaciónenReumatologíayEspecialidadesMédicas, Bogota, Not set
Preventive Care S.A.S, Chia, Not set
Klinik for Led og bindevævssygdomme, Aarhus N, Not set
Frederiksberg Hospital - Parker Institutet (Artrose), Frederiksberg, Not set
Centre Hospitalier de Clermont-Ferrand-Hopital Gabriel Montpied, Clermont-Ferrand, Not set
Aphp-Hopital La Pitie Salpetriere-3, PARIS cedex 13, Not set
CHU Pitié-Salpétrière, PARIS cedex 13, Not set
Ap-Hp-Hopital Europeen Georges Pompidou, Paris, Not set
Hôpital Européen Georges Pompidou, Paris, Not set
Hospices Civils de Lyon-Hopital Lyon Sud-1, Pierre Benite, Not set
Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-2, Toulouse, Not set
Akershus Universitetssykehus, Nordbyhagen, Not set
Oslo us HF, Aker sykehus, Oslo, Not set
Senter for sykelig overvekt i Helse Sør-Øst, Tønsberg, Not set
PIH "Clin Hosp "RZD-Medicina" former Kazan OJSC Rus Railways, Kazan, Not set
LLC Medical center "Maksimum Zdorovia", Kemerovo, Not set
National Medical Research Center of Endocrinology, Moscow, Not set
Setchenov First Moscow State Medical University, Moscow, Not set
Federal Bureau for Medical and Social Expertise, Moscow, Not set
Consultative & Diagnostic Center with a Outpatient Hospital, Saint-Petersburg, Not set
SIH "Saratov Regional Clinical Hospital for War Veterans", Saratov, Not set
Siberian State Medical University, Tomsk, Not set
Voronezh Regional Clinical Consultive-diagnostic Centre, Voronezh, Not set
SBCI HC Yaroslavl region "Central City Hospital", Yaroslavl, Not set
King Abdulaziz Hospital-Al Ahsa-National Guard, Al Ahsa, Not set
King Khaled University Hospital,King Saud Univ. Med. City, Riyadh, Not set
King Faisal Specialist Hospital & Research Centre, Riyadh, Riyadh, Not set
King Fahad Medical City, Riyadh, Not set
Phoenix Pharma, Port Elizabeth, Eastern Cape
Dr Wilhase's rooms, Boksburg, Gauteng
Botho ke Bontle Health Services, Pretoria, Gauteng
Maxwell Centre, Durban, KwaZulu-Natal
Dr J Reddy, Durban, KwaZulu-Natal
Complejo Hospitalario Universitario A Coruña, La Coruña, Not set
Hospital Clinico San Carlos, Madrid, Not set
Clínica Nuevas Tecnologías en Diabetes y Endocrinología, Sevilla, Not set
Forskningsmottagning Internmedicin (tidigare KFE), Malmö, Not set
S:t Göran Sjukhus, Stockholm, Not set
Department of Metabolism and Endocrinology, Stockholm, Not set
Medicinkliniken Överviktsenheten USÖ, Örebro, Not set
Conditions: Obesity
A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Semaglutide (COMBINE 2)
Completed
This study will compare the new medicine IcoSema, which is a combination of insulin icodec and semaglutide, taken once a week, to semaglutide taken once a week in people with type 2 diabetes.
The study will look at how well IcoSema controls blood sugar level in people with type 2 diabetes compared to semaglutide.
Participants will either get IcoSema or semaglutide. Which treatment participants get is decided by chance. IcoSema is a new medicine that doctors cannot prescribe. Doctors can alread... Read More
This study will compare the new medicine IcoSema, which is a combination of insulin icodec and semaglutide, taken once a week, to semaglutide taken once a week in people with type 2 diabetes.
The study will look at how well IcoSema controls blood sugar level in people with type 2 diabetes compared to semaglutide.
Participants will either get IcoSema or semaglutide. Which treatment participants get is decided by chance. IcoSema is a new medicine that doctors cannot prescribe. Doctors can already prescribe semaglutide in many countries.
Participants will get IcoSema or semaglutide, which they must inject once a week with a pen, which has a small needle, in a skin fold in the thigh, upper arm, or stomach.
The study will last for about 1 year and 1 month. Participants will have 18 clinic visits, 34 phone/video calls with the study doctor, and 4 contacts with the site that can either be clinic visits or phone/video calls.
At 11 clinic visits participants will have blood samples taken. At 7 clinic visits participants cannot eat or drink (except for water) for 8 hours before the visit.
Women cannot take part if pregnant, breast-feeding or plan to get pregnant during the study period. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2025
Locations: Univ of AL at Birmingham_BRM, Birmingham, Alabama +136 locations
Univ of AL at Birmingham_BRM, Birmingham, Alabama
Pri Med Grp dba/Gil Ctr Fam, Gilbert, Arizona
Clinical Research Institute of Arizona, Sun City West, Arizona
John Muir Physicians Network, Concord, California
Velocity Clin Res Los Angeles, Los Angeles, California
Velocity Clin Res Wstlke, Los Angeles, California
Valley Clinical Trials, Inc., Northridge, California
Premier Medical Center, Inc., Toluca Lake, California
Northeast Research Institute, Fleming Island, Florida
Northeast Res Inst. Inc., Jacksonville, Florida
Est Cst Inst for Rsrch,Jksnvil, Jacksonville, Florida
South Broward Research LLC, Miramar, Florida
Adult Medicine of Lake County, Inc., Mount Dora, Florida
Florida Inst For Clin Res, Orlando, Florida
Florida Institute For Clinical Research, Orlando, Florida
Oviedo Medical Research, LLC, Oviedo, Florida
Metabolic Research Institute Inc, West Palm Beach, Florida
Javara/Privia Med Grp GA,LLC, Albany, Georgia
East West Med Res Inst, Honolulu, Hawaii
Saltzer Medical Group Research, Nampa, Idaho
Endeavor Health, Skokie, Illinois
Ileana J Tandron APMC, Slidell, Louisiana
MedStar Hlth Res Institute, Hyattsville, Maryland
Northern Pines Hlth Ctr, PC, Buckley, Michigan
Palm Research Center Inc-Vegas, Las Vegas, Nevada
John J Shelmet, MD, Lawrenceville, New Jersey
Albuquerque Clin Trials, Inc., Albuquerque, New Mexico
Southgate Medical Group, LLP, West Seneca, New York
PharmQuest Life Sciences LLC, Greensboro, North Carolina
Diab & Endo Assoc of Stark Co, Canton, Ohio
New Venture Medical Research, Wadsworth, Ohio
Thomas Jefferson Univ Di Rsrch Ctr, Philadelphia, Pennsylvania
Palmetto Clinical Research, Summerville, South Carolina
AM Diabetes And Endocrinology Center, Bartlett, Tennessee
Chattanooga Medical Research, LLC, Chattanooga, Tennessee
Amarillo Med Spec LLP, Amarillo, Texas
Texas Diab & Endo, P.A., Austin, Texas
Texas Diabetes & Endocrinology, Austin, Texas
Osvaldo A. Brusco MD PA, Corpus Christi, Texas
North Texas Endocrine Center, Dallas, Texas
UT Southwestern Med Cntr, Dallas, Texas
Diabetes and Thyroid Ctr of FW, Fort Worth, Texas
DCOL Ctr for Clin Res, Longview, Texas
Texas Diabetes & Endocrinology_Round Rock, Round Rock, Texas
NE Clin Res of San Antonio, San Antonio, Texas
Sugar Lakes Family Practice PA, Sugar Land, Texas
Chrysalis Clinical Research, Saint George, Utah
Javara Inc. / Privia Medical Group LLC_Forest, Forest, Virginia
Javara Inc/Privia Md GpLLC Fst, Forest, Virginia
TPMG Clinical Research, Newport News, Virginia
Centro de Diabetes Metabolismo e Endocrinologia, Fortaleza, Ceara
Instituto de Ciências Farmacêuticas de Estudos e Pesquisas, Aparecida de Goiania, Goias
Quanta Diagnóstico Nuclear / Medicina Nuclear Alto da XV, Curitiba, Parana
Centro de Diabetes Curitiba, Curitiba, Parana
Instituto São José dos Campos em Pesquisas Médicas, São José dos Campos, Sao Paulo
BR Trials - Ensaios Clínicos e Consultoria Ltda., São Paulo, Sao Paulo
LMC Clinical Res Thornhill, Concord, Ontario
Medical Trust Clinics, Inc., Courtice, Ontario
Wharton Med Clin Trials, Hamilton, Ontario
Western Univ. Cnt for Studies in Fam Med, London, Ontario
Bluewater Clin Res Group,Inc, Sarnia, Ontario
LMC Endo Centres Ltd.(Bayview), Toronto, Ontario
Recherche GCP Research, Montreal, Quebec
Recherche GCP Research, Montreal, Quebec
LMC Clin Rsrch Inc. (Montreal), Montreal, Quebec
LMC Clin Rsrch Inc. (Montreal), Saint-Laurent, Quebec
Recherche Clinique Sigma inc, Quebec, Not set
Anhui Provincial Hospital-Endocrinology, Hefei, Anhui
Peking University People's Hospital-Endocrinology, Beijing, Beijing
Chongqing University Three Gorges Hospital, Chongqing, Chongqing
Huizhou Central People's Hospital-Endocrinology, Huizhou, Guangdong
Changzhou No.2 People's Hospital, Yanghu Branch, Changzhou, Jiangsu
The Second Affiliated Hospital of Nanjing Medical University-Endocrinology, Nanjing, Jiangsu
Jinan Central Hospital, Ji'nan, Shandong
Huashan Hospital Fudan University-Endocrinology, Shanghai, Shanghai
Shanghai Huashan Hospital, Affiliated to Fudan University, Shanghai, Shanghai
Shanghai Fifth People's Hospital-Endocrinology, Shanghai, Shanghai
General Hospital of Tianjin Medical University-Endocrinology, Tianjin, Tianjin
Tianjin Medical University Chu Hsien-I Memorial Hospital-Endocrinology, Tianjin, Tianjin
Centre Hospitalier Universitaire de Rouen - Hopital de Bois Guillaume, Bois-Guillaume, Not set
Les Hopitaux de Chartres-Hopital Louis Pasteur, Le Coudray, Not set
Groupe Sos Sante-Hopital Le Creusot-Hotel Dieu-1, Le Creusot, Not set
Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-1, Saint Herblain, Not set
Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-2, Toulouse, Not set
Centre de Recherche Clinique Portes Du Sud, Venissieux, Not set
Evangelismos Hospital, Athens, Not set
Iatriko Psychicou Private Clinic, Athens, Not set
'G. Gennimatas' General Hospital of Athens, Athens, Not set
Univ Gen Hospital Larisa, Larissa, Not set
General Hospital of Thessaloniki 'G. Gennimatas, Thessaloniki, Not set
"Ippokrateio" G.H. of Thessaloniki, Thessaloniki, Not set
"Thermi" Private Hosital, Thessaloniki, Not set
General Hospital of Thessaloniki "G.Papanikolaou", Thessaloniki, Not set
PTE-AOK II. Belgyogyaszati Klinika es Nephrologiai Centrum, Pécs, Baranya Vármegye
Debreceni Egyetem Belgyógyászati Klinika, Debrecen, Hajdu-Bihar
Debreceni Egyetem Klinikai Központ Belgyógyászati Klinika D épület, Debrecen, Hajdu-Bihar
MED-TIMA Kft., Budapest, Not set
Linn clinic - Clalit Health Services, Haifa, Not set
Clalit sick fund Herzeliya, Herzeliya, Not set
Diabetes Clinic Wolfson MC, Holon, Not set
Diabetes Unit Hadassah Ein Karem MC, Jerusalem, Not set
Diabetes Clinic Meir MC, Kfar Saba, Not set
Endrocrinolgy Clinic - Sheba Medical Center, Tel Hashomer, Not set
Heiwadai Hospital, Miyazaki-shi, Miyazaki
The Institute of Medical Science, Asahi Life Foundation, Chuo-ku, Tokyo, Not set
Futata Tetsuhiro Clinic Meinohama, Fukuoka-shi, Fukuoka, Not set
Gifu University Hospital, Gifu, Not set
Naka Kinen Clinic, Ibaraki, Not set
Takatsuki Red Cross Hospital, Osaka, Not set
Shimizu Clinic Fusa, Saitama, Not set
Soka Sugiura Internal Medicine Clinic_Internal Medicine, Saitama, Not set
Shinden Higashi Clinic, Sendai-shi, Miyagi, Not set
Irkutsk State Medical Academy of Postgraduate Education, Irkutsk, Not set
National Medical Research Center of Endocrinology, Moscow, Not set
Limited Law Company "Healthy Family" Medicine Center", Novosibirsk, Not set
BHI of Omsk Region "City Hospital № 3", Omsk, Not set
Penza Regional Clinical Hospital named after N.N. Burdenko, Penza, Not set
Rostov State Medical University_Rostov-on-Don, Rostov-on-Don, Not set
Polyclinic #2 in Yoshkar-Ola, Yoshkar-Ola, Not set
DIOLI s.r.o., Kosice, Not set
HUMAN-CARE s.r.o., Kosice, Not set
DIADAN, s.r.o. Kosice, Kosice, Not set
FNsP L. Pasteura, Kosice, Not set
DIA - KONTROL s.r.o., Levice, Not set
MUDr. Alena Lomencikova, s.r.o, Turcianske Teplice, Not set
Primary Care Trial Center, PTC ,Gothia Forum, Göteborg, Not set
Centrum for Diabetes, Academical Specialist Centrum, Stockholm, Not set
Enheten för Kliniska Studier (EKS), Örebro, Örebro, Not set
Luzerner Kantonsspital, Luzern 16, Not set
Kantonsspital Olten, Olten, Not set
Diabetes Adipositas Zentrum Zürich, Zollikerberg, Not set
Chung Shan Medical University Hospital, Taichung City, Not set
Chung Shan Medical University Hospital, Taichung, Not set
Chi Mei Medical Center, Tainan City, Not set
National Cheng Kung University Hospital, Tainan, Not set
Taipei Veterans General Hospital, Taipei, Not set
Chang Gung Medical Foundation - Linkou Branch, Taoyuan, Not set
Conditions: Diabetes Mellitus, Type 2
A Research Study to Compare a Medicine Called Semaglutide Against Placebo in People With Peripheral Arterial Disease and Type 2 Diabetes
Completed
This study is done to see if semaglutide has an effect on walking ability compared with placebo (dummy medicine) in people with peripheral arterial disease (PAD) and type 2 diabetes. Participants will either get semaglutide or placebo ("dummy") medicine - which treatment participants get is decided by chance. Semaglutide is a medicine for type 2 diabetes that can be prescribed by doctors in some countries. Participants will get the study medicine (semaglutide or placebo) in a pre-filled pen for... Read More
This study is done to see if semaglutide has an effect on walking ability compared with placebo (dummy medicine) in people with peripheral arterial disease (PAD) and type 2 diabetes. Participants will either get semaglutide or placebo ("dummy") medicine - which treatment participants get is decided by chance. Semaglutide is a medicine for type 2 diabetes that can be prescribed by doctors in some countries. Participants will get the study medicine (semaglutide or placebo) in a pre-filled pen for injection. Participants must inject it once a week into the stomach area, thigh, or upper arm, at any time of the day. The study will last for about 59 weeks. Participants will have 8 clinic visits and 1 phone call with the study doctor. At some clinic visits, participants will have blood tests. At some visits participants will also do a treadmill test to measure how far they can walk. Women cannot take part if pregnant, breast-feeding or planning to become pregnant during the study period. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/07/2025
Locations: Angel City Research, Inc., Los Angeles, California +123 locations
Angel City Research, Inc., Los Angeles, California
St. Joseph Heritage Healthcare_Mission Viejo, Mission Viejo, California
Rocky Mount Reg VA Med-DN, Aurora, Colorado
Clearwater Cardiovascular Consultants, Clearwater, Florida
Tampa Bay Medical Research, Clearwater, Florida
DMI Research, Pinellas Park, Florida
University of South Florida, Tampa, Florida
Aiyan Diabetes Center, Martinez, Georgia
Endeavor Health Glenbook Hosp, Glenview, Illinois
Cardiovascular Rsrch of NW_IN, Munster, Indiana
LOUISIANA HEART Center, Covington, Louisiana
Amicis Centers of Clinical Research, Saint Louis, Missouri
Nebraska West Iowa Hlth System, Omaha, Nebraska
Capital Area Research LLC, Camp Hill, Pennsylvania
Penn Presb Med Ctr, Philadelphia, Pennsylvania
Northwest Houston Cardiology, P.A., Houston, Texas
Texas Tech University Health Science Center, Lubbock, Texas
Selma Medical Associates, Winchester, Virginia
Universitätsklinik für Innere Medizin Graz, Graz, Not set
Klinik Landstraße, Wien, Not set
AKH Wien, Wien, Not set
Imeldaziekenhuis Bonheiden - Thoracic and Vascular Surgery, Bonheiden, Not set
Ziekenhuis Oost-Limburg AV - Thoracic, Genk, Not set
UZ Gent - Thoracale Vasculaire Heelkunde, Gent, Not set
UZ Gent_Gent_1, Gent, Not set
AZ Groeninge - Thoracic Vascular Surgery, Kortrijk, Not set
UZ Leuven - Hart en Vaatziekten, Leuven, Not set
North York Diagn & Cardiac Ctr, North York, Ontario
North York Diagnostic and Cardiac Centre, North York, Ontario
ViaCar Recherche Clinique Inc, Brossard, Quebec
Ecogene-21, Chicoutimi, Quebec
Clinique Sante Cardio MC, Montreal, Quebec
Montreal Heart Institute, Montreal, Quebec
CHU de Quebec-Universite Laval, Quebec, Not set
Institut universitaire de cardiologie, Quebec, Not set
Xuanwu Hospital Capital Medical University, Beijing, Beijing
The first hospital of Jilin University, Changchun, Jilin
1st Affiliated Hosp of Xi'an JiaoTong Uni Medical College, Xi'an, Shaanxi
The First Affiliated Hospital of Xi'an Jiaotong University-Cardiovascular, Xi'an, Shaanxi
Tianjin Union Medical Center-Cardiology, Tianjin, Not set
Tianjin Union Medicine Centre, Tianjin, Not set
CTC Hodonin s.r.o., Hodonin, Not set
EDUMED Jaromer, Jaroměř, Not set
Kucera, Ostrava Dubina, Not set
Diabetologicka ambulance Plzen, Plzen, Not set
Kolding Sygehus Karkirurgi, Kolding, Not set
Rigshospitalet Karkirurgisk afd. RK 3111, København Ø, Not set
Karkirurgisk Afsnit, Viborg, Not set
Kardiologische Praxis, Bad Homburg, Not set
Herz- und Diabeteszentrum NRW - Bad Oeynhausen, Bad Oeynhausen, Not set
Kreutzmann, Dresden, Not set
Medizinische Klinik und Poliklinik III/Angiologie TU Dresden, Dresden, Not set
MVZ CCB Frankfurt Und Main-Taunus GbR, Frankfurt, Not set
Institut für Diabetesforschung GmbH Münster - Dr. med. Rose, Münster, Not set
Gemeinschaftspraxis Haggenmiller/Jeserich, Nürnberg, Not set
Zentrum für klinische Studien Alexander Segner, Saint Ingbert-Oberwürzbach, Not set
University Hospital of Athens ATTIKON, Athens, Attica
"Laiko" General Hospital of Athens, Athens, Not set
Konstantopouleio G.H. of Athens, "Agia Olga", Athens, Not set
"Hygeia" General Hospital of Athens, Athens, Not set
General Hospital of Chios "Skilitsio", Chios, Not set
General Hospital of Lamia, Lamia, Not set
'Ippokrateio' General Hospital of Thessaloniki, Thessaloniki, Not set
Szegedi Tudományegyetem II. sz Belgyógyászati és Kardiológia, Szeged, Csongrád-Csanád
Léda Platán Magánklinika, Zalaegerszeg, Zala Megye
Szent Margit Rendelőintézet Nonprofit Kft., Budapest, Not set
Szent Imre Egyetemi Oktatókórház Angiológia, Budapest, Not set
Semmelweis Egyetem Városmajori Szív- és Érgyógyászat, Budapest, Not set
Coromed SMO Kft., Pécs, Not set
Shri B D Mehta Mahavir Heart Institute, Surat, Gujarat
Shri B. D. Mehta Mahavir Heart Institute, Surat, Gujarat
Shri Krishna Hrudayalaya & Critical Care Centre, Nagpur, Maharashtra
Shrikrishna Hrudayalaya and critical care centre, Nagpur, Maharashtra
Vijan Hospital & Research Centre, Nashik, Maharashtra
SP Medical College, Bikaner, Rajasthan
Osmania General Hospital, Hyderabad, Telangana
Udyaan Health Care, Lucknow, Uttar Pradesh
Sir Ganga Ram Hospital, New Delhi, Not set
Akaicho Clinic, Chiba-shi, Chiba, Not set
New Tokyo Heart Clinic_Matsudo-shi, Chiba,, Chiba, Not set
Higashi Takarazuka Satoh Hospital, Hyogo, Not set
Nishiyamado Keiwa Hospital, Ibaraki,, Not set
Naka Kinen Clinic, Ibaraki, Not set
Omihachiman Community Medical Center_Omihachiman-shi, Siga, Omihachiman-shi, Siga, Not set
Minamiosaka Hospital, Osaka, Not set
Saitama Cardiovascular and Respiratory Center, Saitama, Not set
Omi Medical Center, Shiga, Not set
Minamino Cardiovascular Hospital, Tokyo, Not set
Stradini PAD, Riga, Not set
Hospital Universiti Sains Malaysia, Kota Bharu, Kelantan
Hospital Tengku Ampuan Afzan, Kuantan, Pahang
University Malaya Medical Centre, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
National Heart Institute, Kuala Lumpur, Not set
Hospital Queen Elizabeth II, Sabah, Not set
Sørlandet sykehus HF Kristiansand, Kristiansand, Not set
OUS, Aker, Oslo, Not set
Med. Cent. Diabet. Endo. Metabol. DIAB-ENDO-MET, Krakow, Malopolskie
UniCardia & UniMedica & UniEstetica, Krakow, Not set
Centrum Medyczne OMEDICA, Poznan, Not set
Velocity Nova Sp. z o.o., Pulawy, Not set
Gabinety Lekarskie LabMed, Szczecin, Not set
DoktorA, Warszawa, Not set
Centrum Badan Klinicznych, Wroclaw, Not set
Hospital Vithas Sevilla, Castilleja Dela Cuesta Sevilla, Not set
Hospital Reina Sofia, Córdoba, Not set
Hospital Universitario de la Princesa, Madrid, Not set
Hospital Gregorio Marañón, Madrid, Not set
Hospital Virgen de la Macarena, Sevilla, Not set
Kärlkirurgen/kärllab, Göteborg, Not set
Kärlmottagningen, Uppsala, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set
China Medical University Hospital, Taichung, Not set
Kuang Tien General Hospital, Taichung, Not set
National Cheng Kung University Hospital, Tainan, Not set
National Taiwan University Hospital_main, Taipei, Not set
Taipei Veterans General Hospital, Taipei, Not set
Chang Gung Medical Foundation - Linkou Branch, Taoyuan, Not set
Srinagarind Hospital, Muang, Khon Kaen
Phramongkutklao Hospital-cardio, Bangkok, Not set
Research Institute for Health Sciences, CMU, Chiang Mai, Not set
Rihes - Research Institute for Health Sciences, Chiang Mai, Not set
Srinagarind Hospital, Khon Kaen, Not set
Maharat Nakhon Ratchasima Hospital_Ratchasima, Nakhon Ratchasima, Not set
Thammasat University Hospital_Pathumthani, Pathumthani, Not set
Conditions: Diabetes Mellitus, Type 2, Peripheral Arterial Disease
STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss
Recruiting
The study is testing how well semaglutide can help adolescents with excess body weight to lose weight and to maintain weight loss. All participants in the study will receive semaglutide as a weekly injection. The study medicine is injected with a thin needle in the stomach, thighs or upper arms. All participants will get semaglutide treatment for a minimum of 3 years.
The study is testing how well semaglutide can help adolescents with excess body weight to lose weight and to maintain weight loss. All participants in the study will receive semaglutide as a weekly injection. The study medicine is injected with a thin needle in the stomach, thighs or upper arms. All participants will get semaglutide treatment for a minimum of 3 years. Read Less
Gender:
ALL
Ages:
Between 12 years and 15 years
Trial Updated:
07/02/2025
Locations: Neighborhood Healthcare, Escondido, California +96 locations
Neighborhood Healthcare, Escondido, California
Clinical Neuroscience Solution, Orlando, Florida
TMH Physician Partners Endo, Tallahassee, Florida
Children's Healthcare Atlanta, Atlanta, Georgia
Columbus Research Foundation, Columbus, Georgia
Eastside Bariatric and Gen Surg, Snellville, Georgia
Solaris Clinical Research, Meridian, Idaho
Synexus Clinical Research US Inc.-Chicago, Chicago, Illinois
Indiana University Hospital, Indianapolis, Indiana
University Of Iowa Hospitals and Clinics, Iowa City, Iowa
Pennington Biom Res Ctr, Baton Rouge, Louisiana
Barry J. Reiner, MD LLC, Baltimore, Maryland
University of Minnesota, Minneapolis, Minnesota
Mississippi CTR for ADV MED, Madison, Mississippi
UBMD Peds-Div of Endo/Diabetes, Buffalo, New York
UBMD Peds-Div of Endo/Diabetes, Buffalo, New York
WakeMed Childn Endo-Dbt_Raleig, Raleigh, North Carolina
Valley Weight Loss Clinic, Fargo, North Dakota
Centricity Research - Ohio, Columbus, Ohio
PriMed Clinical Research, Dayton, Ohio
UPMC Child Hosp-Pittsburgh, Pittsburgh, Pennsylvania
UPMC Child Hosp-Pittsburgh, Pittsburgh, Pennsylvania
Coastal Carolina Research Ctr, North Charleston, South Carolina
Clinical Neuroscience Solutions, Memphis, Tennessee
Texas Diabetes Institute, San Antonio, Texas
Clinical Trials of Texas Inc, San Antonio, Texas
Health Res of Hampton Roads, Newport News, Virginia
Virginia Commonwealth Univ, Richmond, Virginia
UZ Brussel - Universitair Ziekenhuis Brussel, Brussel, Not set
Cliniques universitaires Saint-Luc, Bruxelles, Not set
UZA - Universitair Ziekenhuis Antwerpen, Edegem, Not set
Uz Leuven, Leuven, Not set
Alberta Children's Hospital, Calgary, Alberta
Stollery Children's Hospital, Edmonton, Alberta
BC Children's Hospital, Vancouver, British Columbia
Markham Stouffville Hosp, Markham, Ontario
The Hospital for Sick Children, Toronto, Ontario
McMaster Children's Hospital, West Hamilton, Ontario
Maison de Sante Prevention, Montreal, Quebec
McGill Uni Health Ctre - Glen Site, Montreal, Quebec
Aalborg Universitetshospital, Aalborg, Not set
Aarhus Universitetshospital, Steno Diabetes Center Aarhus, Aarhus, Not set
Holbæk Sygehus, Holbæk, Not set
Centre Hospitalier Universitaire de Lille-Hopital Jeanne de Flandre, Lille Cedex, Not set
Centre Hospitalier Universitaire de Lille-Hopital Jeanne de Flandre, Lille Cedex, Not set
Fondation Lenval Nice, Nice, Not set
Ap-Hp-Hopital Armand Trousseau, Paris, Not set
Centre Hospitalier Universitaire de Rouen-Hopital Charles Nicolle, Rouen cedex, Not set
Centre Hospitalier Universitaire de Rouen-Hopital Charles Nicolle, Rouen cedex, Not set
Hopital Des Enfants-1, Toulouse Cedex 9, Not set
Kinderkrankenhaus Bochum, Bochum, Not set
Universitätsmedizin Göttingen - Klinik für Kinder-und Jugendmedizin, Göttingen, Not set
Auf der Bult - Klinik für Diabetologie, Endokrinologie, Gastroenterologie und Klinische Forschung, Hannover, Not set
Auf der Bult - Klinik für Diabetologie, Endokrinologie, Gastroenterologie und Klinische Forschung, Hannover, Not set
Universitätsklinikum Leipzig - Klinik und Poliklinik für Kinder- und Jugendmedizin, Leipzig, Not set
Universitätsklinikum Leipzig - Klinik und Poliklinik für Kinder- und Jugendmedizin, Leipzig, Not set
Deutsches Zentrum für Kinder- und Jugendgesundheit (DZKJ), Ulm, Not set
Universitätsklinikum Ulm für Kinder- und Jugendmedizin, Ulm, Not set
U.G.H. "Attikon", Pediatric Endocrinology Outpatient Clinic, Athens, Not set
P & A Kyriakou Childrens' Hospital, Goudi/Athens, Not set
General University of Patra - Paediatric Department, Patra, Not set
'Ippokrateio' General Hospital of Thessaloniki, Thessaloniki, Not set
Ippokrateio Gen Hosp of Thessaloniki, 1st Pediatric Clinic, Thessaloniki, Not set
IRCCS Meyer Firenze, Florence, Toscana
Ospedale dei Bambini "Vittore Buzzi", Milan, Not set
Bambin Gesù, Roma, Not set
IRCCS materno infantile Burlo Garofolo, Trieste, Not set
AOU Integrata di Verona - Ospedale Civile Maggiore, Verona, Not set
CHRISTUS - Latam Hub Excellence and Innovation Center, Monterrey, Nuevo León
Centro de Estudios de Investigación Metabólicos y Cardio, Ciudad Madero, Tamaulipas
Consultorio de Endocrinología y Pediatría, Puebla, Not set
Consultorio de Endocrinología y Pediatría, Puebla, Not set
Klinika Pediatrii, Endokrynologii, Diabetologii I chorób Metabolicznych, Uniwersyteckiego Szpitala Klinicznego in Wrocław, Wrocław, Dolnośląskie
Copernicus Podmiot Leczniczy Sp. z o.o., Gdańsk, Not set
Górnośląskie Centrum Zdrowia Dziecka Im. Św. Jana Pawla II Samodzielny Publiczny Szpital Kliniczny Nr 6 SUM w Katowicach, Katowice, Not set
Kliniczny Szpital Wojewodzki nr 2 im. Sw. Jadwigi Krolowej w Rzeszowie, Rzeszów, Not set
ELIPSA - Elżbieta Lipska praktyka lekarska Ośrodek Endokrynologii i Diabetologii Dziecięcej, Stanisławów Pierwszy Nieporęt, Not set
Instytut ''Pomnik - Centrum Zdrowia Dziecka'', Warszawa, Not set
Samodzielny Publiczny Szpital Kliniczny Nr 1 im. Prof. Szyszko, Zabrze, Not set
UMED Clinical Trials sp. z o.o., Łódź, Not set
King Abdulaziz Hospital-Al Ahsa-National Guard, Al Ahsa, Not set
National Guard Hospital - Jeddah, Jeddah, Not set
King Khaled University Hospital,King Saud Univ. Med. City, Riyadh, Not set
King Faisal Specialist Hospital & Research Centre, Riyadh, Riyadh, Not set
National Guard Hospital_Riyadh, Riyadh, Not set
Barn- och ungdomsmedicinsk mottagning Falun lasarett, Falun, Not set
Hallands sjukhus Halmstad, Halmstad, Not set
Barnöverviktsenheten, SUS Malmö, Malmö, Not set
Sundsvalls sjukhus, Sundsvall, Not set
Akademiska sjukhuset Uppsala, Uppsala, Not set
Birmingham Children's Hospital, Birmingham, Not set
University Hospitals Bristol & Weston NHS Foundation Trust, Bristol, Not set
Leeds Children's Hospital, Leeds, Not set
Alder Hey Children's Hospital, Liverpool, Not set
Paediatric Services - UCL, London, Not set
Sheffield Children's Hospital, Sheffield, Not set
Southampton General Hospital, Southampton, Not set
Conditions: Obesity
A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity
Recruiting
This study will look at how well CagriSema helps people with obesity lose weight compared to a "dummy medicine". CagriSema is a new medicine developed by Novo Nordisk. CagriSema cannot yet be prescribed by doctors. The study has two parts: First part is called the main phase and will last for 2 years, and second part is called the extension phase and will last for 1 year. In the main phase participants will either get CagriSema or "dummy medicine". Which treatment participants get is decided by... Read More
This study will look at how well CagriSema helps people with obesity lose weight compared to a "dummy medicine". CagriSema is a new medicine developed by Novo Nordisk. CagriSema cannot yet be prescribed by doctors. The study has two parts: First part is called the main phase and will last for 2 years, and second part is called the extension phase and will last for 1 year. In the main phase participants will either get CagriSema or "dummy medicine". Which treatment participants get is decided by chance and is not known by participants or the study doctor. In the extension phase participants will get either CagriSema or slowly reduce participants dose of CagriSema if participants had CagriSema in the main phase. Which treatment participants get is decided by chance and is not known by participants or the study doctor in both phases. If participants had "dummy medicine" in the main phase, participants will get CagriSema in the extension phase. Like all medicines, the study medicine may have side effects. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/27/2025
Locations: Valley Clinical Trials, Covina, California +36 locations
Valley Clinical Trials, Covina, California
Diablo Clinical Research, Inc., Walnut Creek, California
Yale University School Of Medicine, New Haven, Connecticut
East West Medical Research Institute_Honolulu, Honolulu, Hawaii
L-MARC Research Center, Louisville, Kentucky
StudyMetrix Research LLC, Saint Peters, Missouri
Spartanburg Medical Research, Spartanburg, South Carolina
Holston Medical Group_Bristol, Bristol, Tennessee
North Texas Endocrine Center, Dallas, Texas
Washington Cntr Weight Mgmt, Arlington, Virginia
CHU Helora - Site Warquignies, Boussu, Not set
Cliniques Universitaires Saint-Luc - Serv Endocrinologie - Diabétologie, Bruxelles, Not set
UZA - UZ Antwerpen - Department of Endocrinology, Edegem, Not set
UZ Leuven - Endocrinology, Leuven, Not set
Dr. M.B. Jones Inc, Victoria, British Columbia
Nova Scotia Health Authority, Halifax, Nova Scotia
Premier Clinical Trial Research Network (PCTRN), Hamilton, Ontario
Alpha Recherche Clinique - Lebourgneuf, Quebec, Not set
Aarhus Universitetshospital, Steno Diabetes Center Aarhus, Aarhus, Not set
Sydvestjysk Sygehus Esbjerg, Esbjerg, Not set
Center for Klinisk Metabolisk Forskning, Hellerup, Not set
Hvidovre Hospital Endokrinologisk forsknings afsnit 159, Hvidovre, Not set
Sjællands Universitetshospital, Køge, Not set
Unidade Local De Saude De Matosinhos E.P.E., Senhora Da Hora, Matosinhos, Matosinhos
APDP - Associação Protectora dos Diabéticos de Portugal, Lisboa, Not set
APDP - Associação Protectora dos Diabéticos de Portugal, Lisboa, Not set
CUF Descobertas, Lisboa, Not set
Hospital Cuf Descobertas S.A., Lisboa, Not set
Unidade Local de Saude de Sao Joao E.P.E, Porto, Not set
Hospital Luz Arrabida, S.A., Vila Nova de Gaia, Not set
Southmead Hospital, Bristol, Not set
Addenbrooke's Hospital_Cambridge, Cambridge, Not set
WISDEM Centre, Coventry, Not set
University Hospital Aintree, Liverpool, Not set
Blizard Institute_Royal London Hospital, London, Not set
Joint Clinical Research Facility - Swansea, Swansea, Not set
Musgrove Park Hospital, Taunton, Not set
Conditions: Obesity
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)
Active Not Recruiting
This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.
Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance.
The study will last for up to 173 weeks (about 3 years and 4 months). Participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans. At 10... Read More
This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.
Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance.
The study will last for up to 173 weeks (about 3 years and 4 months). Participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans. At 10 of the clinic visits participants will have blood samples taken.
Participants must have a study partner, who is willing to take part in the study.
Women cannot take part if pregnant, breastfeeding or plan to become pregnant during the study period.
A cerebrospinal fluid (CSF) sub-study will be performed as a part of the study. The sub-study will be performed on a selection of sites based on their experience with CSF sampling and willingness to participate in this sub-study. The endpoints related to this sub-study are exploratory only. Read Less
Gender:
ALL
Ages:
Between 55 years and 85 years
Trial Updated:
06/24/2025
Locations: Banner Alzheimer's Institute, Phoenix, Arizona +342 locations
Banner Alzheimer's Institute, Phoenix, Arizona
Imaging Endpoints, Scottsdale, Arizona
Banner Sun Health Research Institute, Sun City, Arizona
Advanced Research Center, Inc., Anaheim, California
Fullerton Neurology and Headache Center, Fullerton, California
Pacific Research Network, Lemon Grove, California
Torrance Clin Res Inst, Inc., Lomita, California
ASCLEPES Research Centers,, Long Beach, California
UCLA_Los Angeles, Los Angeles, California
Well Care Medical Center, Panorama City, California
Cedars-Sinai Medical Center, Pasadena, California
Sharp Neurocog Res Ctr, San Diego, California
Syrentis Clinical Research, Santa Ana, California
Calfornia Neurosc Resrch Med, Sherman Oaks, California
Southern California Research LLC, Simi Valley, California
Mountain Neurological Research Center, Inc., Basalt, Colorado
Denver Neurological Research, Denver, Colorado
Mile High Research Center, Denver, Colorado
JEM Research Institute, Atlantis, Florida
Visionary Investigators Network, Aventura, Florida
Brain Matters Research, Delray Beach, Florida
Integrity Clinical Research, LLC, Doral, Florida
Neuropsychiatric Research Cent, Fort Myers, Florida
Finlay Medical Research Group, Greenacres City, Florida
Indago Research & Health Center Inc., Hialeah, Florida
Hlth Cr Family Rehab & Res Ctr, Hialeah, Florida
K2 The Villages, Lady Lake, Florida
K2 Medical Research, Maitland, Maitland, Florida
Hlth Cr Family Rehab & Res Ctr, Miami, Florida
Premier Clin Res Inst, Inc., Miami, Florida
Premier Clinical Research Institute, Inc., Miami, Florida
Novel Clinical Research Center, LLC, Miami, Florida
IMIC, Inc- Medical Research, Miami, Florida
The Neurology Research Group, Miami, Florida
Visionary Inv Ntwrk_Miami, Miami, Florida
Aqualane Clinical Research, Naples, Florida
Suncoast Clin Res Port Richey, New Port Richey, Florida
Suncoast Clinical Research, Inc._New Port Richey, New Port Richey, Florida
Combined Research Orlando Phase I-IV, Orlando, Florida
Advanced Research Consultants, Inc., Palm Beach Gardens, Florida
Intercoastal Medical Group, Sarasota, Florida
The Roskamp Institute, Inc., Sarasota, Florida
Axiom Clinical Research of Florida, Tampa, Florida
Stedman Clinical Trials LLC, Tampa, Florida
Palm Beach Neuro Premiere Res, West Palm Beach, Florida
Conquest Research, Winter Park, Florida
Center for Adv Res & Education, Gainesville, Georgia
Hawaii Neuroscience, Memory Disorders Center, Honolulu, Hawaii
Velocity Clinical Research, Meridian, Meridian, Idaho
Velocity Clinical Research, Meridian, Idaho
Cotton-O'Neil Clinical Research Center, Topeka, Kansas
University of Kentucky_Lexington_0, Lexington, Kentucky
Northern Light Eastern Maine Medical Center, Bangor, Maine
HealthPartners Center for Memory and Aging, Saint Paul, Minnesota
Hattiesburg Clinic, Hattiesburg, Mississippi
Patient First MD,clinical Trials, Middletown, New Jersey
Advanced Memory Research Institute of NJ, Toms River, New Jersey
Neurological Assoc Long Island, Lake Success, New York
Richmond Behavioral Associates, Staten Island, New York
New Hope Clinical Research, Charlotte, North Carolina
AMC Research, LLC, Matthews, North Carolina
Insight Clinical Trials LLC, Beachwood, Ohio
Central States Research, LLC, Tulsa, Oklahoma
Summit Research Network Oregon Inc., Portland, Oregon
The Clinical Trial Center, Jenkintown, Pennsylvania
Coastal Neurology, Port Royal, South Carolina
Genesis Neuroscience Clinic, Knoxville, Tennessee
Vanderbilt Medical Center, Nashville, Tennessee
Univ Of Texas Hlth Science Cntr, Houston, Texas
Glenn Biggs Inst-Alzhm Neuro, San Antonio, Texas
Shirzadi Shahin, MD, Sugar Land, Texas
Integrated Neurology Services, Falls Church, Virginia
Instituto Medico Especializado_Capital Federal, Ciudad de Buenos Aires, Buenos Aires
Instituto de Investigaciones Metabolicas (IDIM), Buenos Aires, Not set
Hospital Italiano, Buenos Aires, Not set
Clínica Nuestra Señora de las Nieves, Caba, Not set
FLENI, Caba, Not set
Instituto Privado Kremer, Córdoba, Not set
Fundación Scherbovsky, Mendoza, Not set
St Vincent's Hospital, Darlinghurst, New South Wales
Southern Neurology, Kogarah, New South Wales
Hunter New England Local Health District - Neuropsychiatry, Waratah, New South Wales
The Prince Charles Hospital, Chermside, Queensland
Medical and Cognitive Research Unit - Austin Health, Ivanhoe, Victoria
LKH-Univ. Kliniken Innsbruck, Innsbruck, Not set
Medizinische Univ. Innsbruck, Innsbruck, Not set
Univ. Klinik für Neurologie, Salzburg, Not set
UZA - UZ Antwerpen - Department of Neurology, Edegem, Not set
AZ Groeninge - Kortrijk - Neurologie, Kortrijk, Not set
L2 IP Instituto de Pesquisas Clinicas Ltda, Brasília, Distrito Federal
Instituto de Neurologia de Curitiba, Curitiba, Parana
Clinica Clinilive Ltda, Maringa, Parana
Núcleo de Pesquisa Clínica do Rio Grande do Sul Ltda., Porto Alegre, Rio Grande Do Sul
CPQuali Pesquisa Clínica Ltda, São Paulo, Sao Paulo
BR Trials - Ensaios Clínicos e Consultoria Ltda., São Paulo, Sao Paulo
Assoc. Paulista para o Desenvolvimento da Medicina - UNIFESP, São Paulo, Sao Paulo
Centro de Psiquiatria Sandra Rushel, Rio de Janeiro, Not set
"MHATNP "Sv. Naum"" EAD, Sofia, Not set
DCC Sv. Vrach and Sv. Sv. Kuzma and Damyan, Sofia, Not set
"UMHAT "Aleksandrovska", Neurology clinic, Sofia, Not set
MMA, MHAT-Sofia, Neurology clinic, Sofia, Not set
OCT Research ULC (dba Okanagan Clinical Trials), Kelowna, British Columbia
Medical Arts Health Research Group_Kelowna, Penticton, British Columbia
Island Health (Research and Capacity Building), Victoria, British Columbia
True North Clinical Research - Halifax, Halifax, Nova Scotia
True North Clinical Research - New Minas, New Minas, Nova Scotia
Ottawa Memory Clinic, Ottawa, Ontario
Recherches Neuro-Hippocampe Inc, Ottowa, Ontario
Memory Program, Toronto, Ontario
Centricity Research LMC, Toronto, Ontario
Sunnybrook Health Sciences Centre, Toronto, Ontario
University Health Network - Toronto Western Hospital, Toronto, Ontario
University Health Network, Toronto, Ontario
Douglas Hosp Res Ctr, Montréal, Quebec
CHU de Quebec-Universite Laval, Québec, Quebec
Neuro Health Centrum s.r.o., Brno-Lisen, Not set
AGE Centrum, Olomouc, Not set
AD71 s.r.o., Praha 10, Not set
Neuropsychiatrie, Praha 6 Dejvice, Not set
Vestra Clinics s.r.o., Rychnov nad Kneznou, Not set
Aarhus Universitetshospital, Aarhus N, Not set
Rigshospitalet - afsnit 8015, København Ø, Not set
Sjællands Universitetshospital_Roskilde, Roskilde, Not set
CRST Helsinki, Helsinki, Not set
Aivotutkimusyksikkö, Kuopio, Not set
CRST Turku, Turku, Not set
Centre Hospitalier Universitaire de Bordeaux-Hopital Pellegrin, Bordeaux, Not set
Hospices Civils de Lyon-Hopital Pierre Wertheimer, Bron, Not set
Centre Hospitalier Universitaire de Dijon-Hopital Le Bocage, Dijon, Not set
Hôpital Roger Salengro, Lille CEDEX, Not set
Assistance Publique Hopitaux de Marseille-Hopital de La Timone-1, Marseille, Not set
Centre Hospitalier Universitaire de Nice-Institut Claude Pompidou, Nice, Not set
Aphp-Hopital Lariboisiere-1, Paris, Not set
Aphp-Hopital La Pitie Salpetriere-3, Paris, Not set
Centre Hospitalier Universitaire Reims-Hopital Maison Blanche, Reims cedex, Not set
Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-2, Saint Herblain, Not set
Les Hopitaux Universitaires de Strasbourg-Hopital de La Robertsau, Strasbourg, Not set
Centre Hospitalier Universitaire de Toulouse-Hopital La Grave, Toulouse, Not set
Hospices Civils de Lyon-Hopital Des Charpennes, Villeurbanne, Not set
Zentrum für klinische Forschung Dr. med. Irma Schöll GmbH, Bad Homburg, Hessen
Universitätsklinikum RWTH Aachen, Neurologie, Aachen, Not set
Studienzentrum Dr. Bischof GmbH, Böblingen, Not set
Neuro Centrum Science GmbH, Erbach, Not set
Universitätsklinikum Hamburg-Eppendorf, Psychiatrie, Hamburg, Not set
Universitätsklinikum Köln - Klinik und Poliklinik für Psychiatrie und Psychotherapie, Köln, Not set
Universitätsmedizin Mainz, Psychiatrie, Mainz, Not set
Zentralinstitut für Seelische Gesundheit - Psychiatrie und Psychotherapie, Mannheim, Not set
LMU Klinikum - Institut für Schlaganfall- und Demenzforschung (ISD), München, Not set
Universitätsklinikum Ulm, Neurologie, Ulm, Not set
Studienzentrum Nord-West, Westerstede, Not set
Henry Dunant Hospital Center,2nd Neurological Department, Athens, Not set
Aiginitio Hospital, 1st Neurology Clinic, Athens, Not set
"Hygeia" General Hospital of Athens, Memory clinic, Athens, Not set
Naval Hospital of Athens, Athens, Not set
University General Hospital of Athens "Attiko", Chaidari, Athens, Not set
Iatriko Athinon (Athens Medical Center),Memory Disorders Cli, Marousi, Not set
AHEPA General University Hospital, Thessaloniki, Not set
EUROMEDICA General Clinic of Thessaloniki,Neurology Dpt, Thessaloniki, Not set
Semmelweis Egyetem ÁOK, Budapest, Not set
DE Kenézy Gyula Campus, Pszichiátriai és Pszichoterápiai Klinika, Debrecen, Not set
DE Gyógyszerfejlesztési Koordinációs Központ Pszichiátria, Debrecen, Not set
Petz Aladar Megyei Korhaz, Gyor, Not set
Petz Aladar Megyei Oktato Korhaz, Gyor, Not set
Bugát Pál Kórház, Gyöngyös, Not set
Somogy Megyei Kaposi Mór Oktató Kórház, Kaposvár, Not set
Psychotech Kft., Pécs, Not set
Belvárosi Egészségház Kft., Zalaegerszeg, Not set
Mercy Hospital Cork, Cork, Not set
St Vincent's University Hospital, Dublin, Not set
Mercer's Institute for Successful Aging, Dublin, Not set
Tallaght University Hospital, Dublin, Not set
The Stroke and Cognition Institute Rambam Medical Center, Haifa, Not set
Cognitive Neurology Clinic, Rabin Campus, Beilinson Hospital, Petach Tikva, Not set
Cognitive Neurology Sourasky Medical Center, Tel Aviv, Not set
Chaim Sheba Medical Center, Heart Screening Clinic, 1st floor, Room 317, Tel Hashomer, Ramat Gan, Not set
AOU Ospedali Riuniti S.O.D, Ancona, Not set
Azienda Ospedaliera Spedali Civili di Brescia, Brescia, Not set
Università degli studi Gabriele D'Annunzio Chieti-Pescara, Chieti, Not set
Fondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, Milano, Not set
IRCCS Ospedale San Raffaele Milano, Milano, Not set
ASST Monza e Brianza Ospedale San Gerardo, Monza, Not set
Ospedale Santa Maria della Misericordia, Perugia, Not set
Pol. Uni. Campus Biomedico UOC Neurologia, Roma, Not set
Policlinico Tor Vergata, Roma, Not set
Policlinico Universitario A.Gemelli Servizio Neuropsicologia, Roma, Not set
Fondazione Santa Lucia IRCCS, Roma, Not set
Iwaki Clinic_Psychosomatic medicine, Anan, Tokushima, Not set
Yachiyo Hospital, Anjo-shi, Aichi, Not set
Abe Clinic, Arakawa-ku,Tokyo, Not set
Memory Clinic Ochanomizu, Bunkyo-ku, Tokyo, Not set
Tokyo Medical And Dental University Hospital, Bunkyo-ku,Tokyo, Not set
Kashiwado Hospital, Chib-shi, Chiba, Not set
Enomoto Internal Medicine Clinic, Chofu-shi,Tokyo, Not set
Shinozuka Hospital, Fujioka-Shi, Gunma, Not set
P-one Clinic, Hachioji-shi, Tokyo, Not set
National Hospital Organization Tenryu Hospital, Hamamatsu-shi, Shizuoka, Not set
Hyogo Brain and Heart Center, Himeji-city, Hyogo, Not set
Tsukazaki Hospital, Himeji-shi, Hyogo, Not set
Himeji Central Hospital Clinic, Himeji-shi, Hyogo, Not set
Hatsuta Neurology Clinic, Hirakata-Shi,Osaka, Not set
Imon Yukari Neurology Clinic, Hiroshima-shi, Hiroshima, Not set
Hikaru-kai Medical Corporation Hiroshima Neurology Clinic, Hiroshima-shi, Hiroshima, Not set
Nagamitsu Clinic, Hofu-shi, Yamaguchi, Not set
Ina Central Hospital, Ina-shi, Nagano, Not set
Kawasaki Saiwai Clinic_Internal Medicine, Kanagawa, Not set
Kishiro Mental Clinic, Kawasaki-shi , Kanagawa, Not set
Koukan Clinic, Kawasaki-shi, Kanagawa, Not set
Teikyo University Hospital, Mizonokuchi_Kawasaki-shi, Kanagawa, Kawasaki-shi, Kanagawa, Not set
Kobe University Hospital_Kobe-shi, Hyogo, Kobe-shi, Hyogo, Not set
National Center of Neurology and Psychiatry, Kodaira-shi, Tokyo, Not set
Southern Tohoku Medical Clinic, Koriyama-shi, Fukushima, Not set
Katayama Medical Clinic, Kurashiki-shi, Okayama, Not set
Nozomi Memory Clinic, Mitaka-shi,Tokyo, Not set
Kikukawa clinic, Nerima-ku, Tokyo, Not set
General Rehabilitation Center · Midori Hospital, Niigata-shi, Niigata, Not set
National Center for Geriatrics and Gerontology, Obu-shi, Aichi, Not set
Jichiidai Station Brain Clinic, Shimotsuke-shi, Tochigi, Not set
Keio University Hospital, Shinjuku-ku, Tokyo, Not set
Shizuoka City Shimizu Hospital_Neurology, Shizuoka-shi, Shizuoka, Not set
Kagawa Prefectural Central Hospital_Takamatsu-shi, Kagawa, Takamatsu-shi, Kagawa, Not set
Saino Clinic, Tokorozawa-shi,Saitama, Not set
Itsuki Hospital, Tokushima-shi, Tokushima, Not set
Alzclinic Tokyo, Tokyo, Not set
Tokyo Center Clinic, Tokyo, Not set
Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Not set
Kurumi CLINIC, Tokyo, Not set
Tokyo Medical Univ. Hospital, Tokyo, Not set
Memory Clinic Toride, Toride-shi, Ibaraki, Not set
MI Clinic, Toyonaka-shi, Osaka, Not set
Medical Corporation Midorikai Wako Hospital, Wako-shi, Saitama, Not set
Dong-A University Medical Center, Busan, Not set
Chungnam National University Hospital, Daejeon, Not set
Chonnam National University Hospital, Gwangju, Not set
Seoul National University Bundang Hospital, Gyeonggi-do, Not set
Gachon University Gil Medical Center, Incheon, Not set
Inha University Hospital, Incheon, Not set
Hanyang University Medical Center, Seoul, Not set
Hanyang university seoul hospital, Seoul, Not set
Konkuk University Medical Center, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center_Seoul, Seoul, Not set
Ewha Womans University Seoul Hospital, Seoul, Not set
Hospital Universitario "Dr. Gonzalo Valdes Valdes", Saltillo, Coahuila
Hospital Universitario Dr. José Eleuterio González_Monterrey, Monterrey, Nuevo León
Centro de Estudios Clínicos y Especialidades Médicas S.C., Monterrey, Nuevo León
Avix Investigación Clínica, S.C., Monterrey, Nuevo León
Hospital Angeles de Culiacan, Culiacan, Sinaloa
Amphia Ziekenhuis, Breda, Not set
Brain Research Center, Den Bosch, Not set
Radboudumc, Nijmegen, Not set
Akershus universitetssykehus - Hukommelsesklinikken, Lørenskog, Not set
Oslo universitetssykehus HF, Ullevål, Oslo, Not set
Master Centre - Dummy, Oslo, Not set
Linden sp. z o.o. sp. k., Kraków, Małopolskie
Centrum Medyczne Neuromed, Bydgoszcz, Not set
Centrum Zdrowia Psychicznego Biomed, Kielce, Not set
Szpital Uniwersytecki w Krakowie od. Neurologii, Kraków, Not set
Centrum Neurologii Klinicznej, Kraków, Not set
Nzoz Neuromed, Lublin, Not set
NZOZ NEURO - KARD Ilkowski i Partnerzy Sp. Part. Lekarzy, Poznan, Not set
Osrodek Alzheimerowski Sp. z o.o., Scinawa, Not set
Centrum Medyczne SENIOR, Sopot, Not set
Centrum Medyczne Neuro Protect, Warszawa, Not set
NZOZ Wrocławskie Centrum Alzheimerowskie, Wroclaw, Not set
Unidade Local De Saude De Matosinhos E.P.E., Senhora Da Hora, Matosinhos, Matosinhos
Hospital de Braga, Braga, Not set
Unidade Local de Saúde de Coimbra, E.P.E., Coimbra, Not set
Unidade Local de Saude do Alto Ave, E.P.E., Guimarães, Not set
Unidade Local De Saude De Lisboa Ocidental E.P.E. - Hospital Egas Moniz, Lisboa, Not set
Hospital Beatriz Ângelo, Loures, Not set
Unidade Local de Saúde de Santo António, E.P.E, Porto, Not set
Campus Neurologico Senior, Torres Vedras, Not set
Sana Monitoring SRL, Bucharest, Not set
Spitalul Clinic Cai Ferate Constanta, Constanta, Not set
Spitalul Clinic Judetean De Urgenta Sfantul Apostol Andrei Constanta, Constanta, Not set
Aria Clinic SRL, Sibiu, Not set
Joint Stock Company "Medical technologies", Ekaterinburg, Not set
Federal Siberian Research Clinical Center under FMBA of Rus, Krasnoyarsk, Not set
FSAEI 1st Moscow Federal Med University na Sechenov, Moscow, Not set
RMAPE, Moscow, Not set
Pirogov Russian National Research Medical University MoH, Moscow, Not set
Ezramed Clinic Llc, Omsk, Not set
Research Center for Treatment and Rehabilitation "Phoenix", Rostov-on-Don, Not set
Psychiatric hospital of st. Nicholas the wonderworker, Saint Petersburg, Not set
N.-E. State Medical University n.a. Mechnikov, Saint Petersburg, Not set
S.M. Kirov Military Medical Academy,Depart.&Clinic Nerv Dis, Saint Petersburg, Not set
Center of Clinica Trials "Nebbiolo", Tomsk, Not set
LLC "Clinic Stolet", Tomsk, Not set
National medical holdiNational medical holding "Medstandard", Ufa, Not set
Neurology clinic, University Clinical Center of Serbia, Belgrade, Not set
Special Hospital for Psychiatric Disorders "Kovin", Kovin, Not set
University clinical center of Vojvodina, Neurology clinic, Novi Sad, Not set
Psych. amb. CENTRUM ZDRAVIA R.B.K., s.r.o. Bardejov, Bardejov, Not set
I. neurologicka klinika LF UK a UNB, Bratislava, Not set
Psychiatricka klinika LF UK a UNB, Bratislava, Not set
Neurologicka klinika UPJS LF a UNLP, Kosice, Not set
Crystal Comfort s.r.o., Vranov nad Toplou, Not set
UKC Ljubljana, Department of Neurology, Ljubljana, Not set
UKC Maribor - neurology, Maribor, Not set
Excellentis Clinical Trial Consultants, George, Eastern Cape
IATROS International, Bloemfontein, Free State
Dr Stanley Lipschitz Clinic Inc, Johannesburg, Gauteng
Denmar Psychiatric Hospital, Pretoria, Gauteng
ACF Neurological service, Cape Town, Western Cape
Flexivest Fourteen Research Centre, Cape Town, Western Cape
Cape Trial Centre, Cape Town, Western Cape
Hospital Santa Creu i Sant Pau, Barcelona, Not set
Fundación ACE, Barcelona, Not set
Fundación CITA, Donostia, Not set
Hospital Ramón y Cajal, Madrid, Not set
Hospital Universitario Quirónsalud Madrid, Pozuelo de Alarcon, Not set
Hospital Universitari General de Catalunya, Sant Cugat del Vallès, Not set
Hospital Universitario Marqués de Valdecilla, Santander, Not set
Hospital Universitario Doctor Peset, Valencia, Not set
Minnesmottagning specialiserad Malmö, Malmö, Not set
Karolinska Universitetssjukhuset, Huddinge, Stockholm, Not set
Geriatriskt centrum, Umeå, Umeå, Not set
Spitalzentrum Biel, Biel-Bienne, Not set
Centre de la Mémoire, Genève, Not set
Centre Leenaards de la mémoire CHUV, Lausanne, Not set
Klinik für Neurologie Kantonsspital St.Gallen, St. Gallen, Not set
Hacettepe University Medical Faculty Hospital, Altindag/Ankara, Not set
Eskisehir Osmangazi University Sağlık Uygulama ve Arastirma, Eskisehir, Not set
Istanbul University Medical Faculty Neurology Department, Istanbul, Not set
Izmir Economics University Medical Point Hospital Neurology D, Izmir, Not set
Ondokuz Mayis University Saglik Uygulama ve Arastirma Merkez, Samsun, Not set
Chebotarev State Institute of Gerontology of the NAMS of Ukr, Kyiv, Not set
Fritchie Centre, Cheltenham, Gloucestershire
Royal Cornhill Hospital, Aberdeen, Not set
RICE - The Research Institute for the Care of Older People, Bath, Not set
Dementia Research Unit,, Crowborough, Not set
Dementia Research Unit, Crowborough, Not set
Ninewells Hospital, Dundee, Not set
Western General Hospital, Edinburgh, Not set
St Pancras Clinical Research, London, Not set
St George's Hospital, London, Not set
Imperial College London - Imperial College Memory Research Centre, London, Not set
Greater Manchester Mental Health NHS Foundation Trust, Manchester, Not set
NeuroClin, Motherwell, Not set
Newcastle University, Newcastle Upon Tyne, Not set
Warneford Hospital, Oxford, Not set
Moorgreen Hospital, Southampton, Not set
Kings Hill Research Centre, Swindon, Not set
Conditions: Early Alzheimer's Disease
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)
Active Not Recruiting
This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.
Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance.
The study will last for up to 173 weeks (about 3 years and 4 months). Participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans. At 10... Read More
This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.
Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance.
The study will last for up to 173 weeks (about 3 years and 4 months). Participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans. At 10 of the clinic visits participants will have blood samples taken.
Participants must have a study partner, who is willing to take part in the study.
Women cannot take part if pregnant, breastfeeding or plan to become pregnant during the study period.
A cerebrospinal fluid (CSF) sub-study will be performed as a part of the study. The sub-study will be performed on a selection of sites based on their experience with CSF sampling and willingness to participate in this sub-study. The endpoints related to this sub-study are exploratory only. Read Less
Gender:
ALL
Ages:
Between 55 years and 85 years
Trial Updated:
06/24/2025
Locations: Banner Alzheimer's Institute, Phoenix, Arizona +389 locations
Banner Alzheimer's Institute, Phoenix, Arizona
Banner Sun Health Research Institute, Sun City, Arizona
Advanced Research Center, Inc., Anaheim, California
Torrance Clin Res Inst, Inc., Lomita, California
ASCLEPES Research Centers,, Long Beach, California
Well Care Medical Center, Panorama City, California
Cedars-Sinai Medical Center, Pasadena, California
Sharp Neurocog Res Ctr, San Diego, California
Syrentis Clinical Research, Santa Ana, California
Calfornia Neurosc Resrch Med, Sherman Oaks, California
Mountain Neurological Research Center, Inc., Basalt, Colorado
Denver Neurological Research, Denver, Colorado
Mile High Research Center, Denver, Colorado
Nuvance Health, Associtd Neuro, Danbury, Connecticut
Research Center for Clinical Studies, Inc, Norwalk, Connecticut
JEM Research Institute, Atlantis, Florida
Visionary Investigators Network, Aventura, Florida
Brain Matters Research, Delray Beach, Florida
Neuropsychiatric Research Cent, Fort Myers, Florida
Finlay Medical Research Group, Greenacres City, Florida
Indago Research & Health Center Inc., Hialeah, Florida
Hlth Cr Family Rehab & Res Ctr, Hialeah, Florida
Galiz Research, Hialeah, Florida
K2 Medical Research, Maitland, Maitland, Florida
Hlth Cr Family Rehab & Res Ctr, Miami, Florida
Premier Clin Res Inst, Inc., Miami, Florida
Premier Clinical Research Institute, Inc., Miami, Florida
Central Miami Medical Institute, Miami, Florida
Novel Clinical Research Center, LLC, Miami, Florida
IMIC, Inc- Medical Research, Miami, Florida
The Neurology Research Group, Miami, Florida
Visionary Inv Ntwrk_Miami, Miami, Florida
Aqualane Clinical Research, Naples, Florida
Suncoast Clinical Research, Inc._New Port Richey, New Port Richey, Florida
K2 Medical Research - Winter Garden, Ocoee, Florida
Advanced Research Consultants, Inc., Palm Beach Gardens, Florida
Intercoastal Medical Group, Sarasota, Florida
Brain Matters Resrch Kane Cntr, Stuart, Florida
Axiom Clinical Research of Florida, Tampa, Florida
Stedman Clinical Trials LLC, Tampa, Florida
Conquest Research, Winter Park, Florida
iResearch Atlanta, LLC, Decatur, Georgia
Hawaii Neuroscience, Memory Disorders Center, Honolulu, Hawaii
Velocity Clinical Research, Meridian, Meridian, Idaho
Velocity Clinical Research, Meridian, Idaho
Josephson Wallack Munshower, Indianapolis, Indiana
Cotton-O'Neil Clinical Research Center, Topeka, Kansas
University of Kentucky_Lexington_0, Lexington, Kentucky
Northern Light Eastern Maine Medical Center, Bangor, Maine
HealthPartners Center for Memory and Aging, Saint Paul, Minnesota
Hattiesburg Clinic, Hattiesburg, Mississippi
Wr-Crcn, Llc, Las Vegas, Nevada
Patient First MD,clinical Trials, Middletown, New Jersey
Advanced Memory Research Institute of NJ, Toms River, New Jersey
Neurological Assoc Long Island, Lake Success, New York
Feinstein Institute for Medical Research, Manhasset, New York
Richmond Behavioral Associates, Staten Island, New York
SUNY Upstate Medical University_Syracuse, Syracuse, New York
New Hope Clinical Research, Charlotte, North Carolina
AMC Research, LLC, Matthews, North Carolina
NeuroScience Research Center, LLC, Canton, Ohio
Insight Clinical Trials LLC, Independence, Ohio
Cleveland Clinic_Lakewood, Lakewood, Ohio
Central States Research, LLC, Tulsa, Oklahoma
Summit Research Network Oregon Inc., Portland, Oregon
Neural Net Research, LLC, Portland, Oregon
Coastal Neurology, Port Royal, South Carolina
Palmetto Clinical Research, Summerville, South Carolina
Genesis Neuroscience Clinic, Knoxville, Tennessee
Vanderbilt Medical Center, Nashville, Tennessee
Texas Diabetes & Endocrinology, Austin, Texas
Balyor College of Medicine, Houston, Texas
Univ Of Texas Hlth Science Cntr, Houston, Texas
Mt. Olympus Medical Research, Katy, Texas
Glenn Biggs Inst-Alzhm Neuro, San Antonio, Texas
Shirzadi Shahin, MD, Sugar Land, Texas
Memory Clinic, Inc, Bennington, Vermont
Integrated Neurology Services, Falls Church, Virginia
Booth Gardner Parkinson's Cre, Kirkland, Washington
Harborview Medical Center, Seattle, Washington
Instituto Medico Especializado_Capital Federal, Ciudad de Buenos Aires, Buenos Aires
Instituto de Investigaciones Metabolicas (IDIM), Buenos Aires, Not set
Hospital Italiano, Buenos Aires, Not set
Clínica Nuestra Señora de las Nieves, Caba, Not set
FLENI, Caba, Not set
Instituto Privado Kremer, Córdoba, Not set
Fundación Scherbovsky, Mendoza, Not set
St Vincent's Hospital, Darlinghurst, New South Wales
HammondCare Greenwich, Greenwich, New South Wales
Southern Neurology, Kogarah, New South Wales
KaRa Institute of Neurological Disease Pty Ltd, Macquarie Park, New South Wales
Hunter New England Local Health District - Neuropsychiatry, Waratah, New South Wales
The Prince Charles Hospital, Chermside, Queensland
Medical and Cognitive Research Unit - Austin Health, Ivanhoe, Victoria
HammondCare, Malvern, Victoria
Alzheimer's Research Australia, Nedlands, Western Australia
Australian Alzheimer's Research Foundation Incorporated, Nedlands, Western Australia
LKH-Univ. Kliniken Innsbruck, Innsbruck, Not set
Medizinische Univ. Innsbruck, Innsbruck, Not set
Univ. Klinik für Neurologie, Salzburg, Not set
Medizinische Universität Wien, Wien, Not set
UZA - UZ Antwerpen - Department of Neurology, Edegem, Not set
UZ Gent - Neurologie, Gent, Not set
AZ Groeninge - Kortrijk - Neurologie, Kortrijk, Not set
UZ Leuven - Geheugenkliniek, Leuven, Not set
Clinique CHC MontLégia - Service Neurologie, Liège, Not set
L2 IP Instituto de Pesquisas Clinicas Ltda, Brasília, Distrito Federal
Instituto de Neurologia de Curitiba, Curitiba, Parana
Clinica Clinilive Ltda, Maringa, Parana
Núcleo de Pesquisa Clínica do Rio Grande do Sul Ltda., Porto Alegre, Rio Grande Do Sul
CPQuali Pesquisa Clínica Ltda, São Paulo, Sao Paulo
BR Trials - Ensaios Clínicos e Consultoria Ltda., São Paulo, Sao Paulo
Centro de Psiquiatria Sandra Rushel, Rio de Janeiro, Not set
"MHATNP "Sv. Naum"" EAD, Sofia, Not set
DCC Sv. Vrach and Sv. Sv. Kuzma and Damyan, Sofia, Not set
"UMHAT "Aleksandrovska", Neurology clinic, Sofia, Not set
MMA, MHAT-Sofia, Neurology clinic, Sofia, Not set
OCT Research ULC (dba Okanagan Clinical Trials), Kelowna, British Columbia
Island Health (Research and Capacity Building), Victoria, British Columbia
Medical Arts Health Research Group, West Vancouver, British Columbia
True North Clinical Research - Halifax, Halifax, Nova Scotia
True North Clinical Research - New Minas, New Minas, Nova Scotia
Recherches Neuro-Hippocampe Inc, Ottowa, Ontario
Kawartha Centre Redefining Healthy Aging, Peterborough, Ontario
Memory Program, Toronto, Ontario
Centricity Research LMC, Toronto, Ontario
Sunnybrook Health Sciences Centre, Toronto, Ontario
St. Michael's Hospital, Toronto, Ontario
St. Michael's Hospital, Toronto, Ontario
University Health Network, Toronto, Ontario
MoCA Research Innovation Inc, Greenfield-Park, Quebec
Douglas Hosp Res Ctr, Montréal, Quebec
CHU de Quebec-Universite Laval, Québec, Quebec
Diex Recherche Sherbrooke Inc., Sherbrooke, Quebec
Beijing Chao-Yang Hospital, Capital Medical University-Neuro, Beijing, Beijing
Beijing Friendship Hospital, Capital Medical University-Neurology, Beijing, Beijing
Beijing Hospital-Neurology, Beijing, Beijing
Xuanwu Hospital Capital Medical University-Neurology, Beijing, Beijing
Beijing Tiantan Hospital, Capital Medical University-Neurology Center, Beijing, Beijing
Beijing An Ding Hospital Capital Medical University-Geriatric Psychiatry, Beijing, Beijing
Peking University Sixth Hospital-Geriatrics, Beijing, Beijing
Beijing Huilongguan Hospital-Geriatrics, Beijing, Beijing
Peking Union Medical College Hospital-Neurology, Beijing, Beijing
The First Affiliated Hospital of Chongqing Medical University-Geriatrics, Chongqing, Chongqing
Fujian Medical University Union Hospital-Neurology, Fuzhou, Fujian
Sun Yat-sen Memorial Hospital, Sun Yat-sen University-Neurol, Guangzhou, Guangdong
Guangzhou First People's Hospital-Neurology, Guangzhou, Guangdong
The Second affiliated hospital of Guangzhou Medical University-Neurology, Guangzhou, Guangdong
Henan Provincial People's Hospital-Neurology, Zhengzhou, Henan
Xiangya Hospital Central South University-Neurology, Changsha, Hunan
Baogang Hospital of Inner Mongolia-Neurology, Baotou, Inner Mongolia
Nanjing Brain Hospital-Neurology, Nanjing, Jiangsu
Nanjing Drum Tower Hospital-Neurology, Nanjing, Jiangsu
Zhongda Hospital Southeast University-Nephrology, Nanjing, Jiangsu
Wuxi Mental Health Center, Wuxi, Jiangsu
Northern Jiangsu People's Hospital-Neurology, Yangzhou, Jiangsu
The Second Affiliated Hospital of Nanchang University-Neurol, Nanchang, Jiangxi
The First Bethune Hospital of Jilin University, Neurology, Changchun, Jilin
Qinghai Provincial People's Hospital-Geriatrics, Xining, Qinghai
Huashan Hospital Fudan University-Neurology, Shanghai, Shanghai
Dongfang Hospital Affiliated to Shanghai Tongji University-Neurology, Shanghai, Shanghai
Shanghai 6th People's Hosp. Affili. to SHJT Univer-Neurology, Shanghai, Shanghai
Shanghai Sixth People's Hospital Affiliated to Shanghai JiaoTong University-Neurology, Shanghai, Shanghai
West China Hospital Sichuan University-Mental health center, Chengdu, Sichuan
General Hospital of Tianjin Medical University-Neurology, Tianjin, Tianjin
Tianjin Huanhu Hospital-Neurology, Tianjin, Tianjin
The First Affiliated Hospital of Zhejiang University School of Medicine-Neurology, Hangzhou, Zhejiang
Poliklinika Solmed, Zagreb, Grad Zagreb
KBC Zagreb, Klinika za neurologiju, Zagreb, Not set
Poliklinika Bonifarm, Zagreb, Not set
Neuro Health Centrum s.r.o., Brno-Lisen, Not set
AGE Centrum, Olomouc, Not set
AD71 s.r.o., Praha 10, Not set
Neuropsychiatrie, Praha 6 Dejvice, Not set
Vestra Clinics s.r.o., Rychnov nad Kneznou, Not set
Aarhus Universitetshospital, Aarhus N, Not set
Rigshospitalet - afsnit 8015, København Ø, Not set
Sjællands Universitetshospital_Roskilde, Roskilde, Not set
CRST Helsinki, Helsinki, Not set
Aivotutkimusyksikkö, Kuopio, Not set
CRST Turku, Turku, Not set
Centre Hospitalier Universitaire de Bordeaux-Hopital Pellegrin, Bordeaux, Not set
Hospices Civils de Lyon-Hopital Pierre Wertheimer, Bron, Not set
Centre Hospitalier Universitaire de Dijon-Hopital Le Bocage, Dijon, Not set
Assistance Publique Hopitaux de Marseille-Hopital de La Timone-1, Marseille, Not set
Centre Hospitalier Universitaire de Nice-Institut Claude Pompidou, Nice, Not set
Aphp-Hopital Lariboisiere-1, Paris, Not set
Aphp-Hopital La Pitie Salpetriere-3, Paris, Not set
Centre Hospitalier Universitaire Reims-Hopital Maison Blanche, Reims cedex, Not set
Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-2, Saint Herblain, Not set
Les Hopitaux Universitaires de Strasbourg-Hopital de La Robertsau, Strasbourg, Not set
Centre Hospitalier Universitaire de Toulouse-Hopital La Grave, Toulouse, Not set
Hospices Civils de Lyon-Hopital Des Charpennes, Villeurbanne, Not set
Universitätsklinikum Köln - Klinik und Poliklinik für Psychiatrie und Psychotherapie, Köln, Not set
Universitätsklinikum Münster, Neurologie, Münster, Not set
Henry Dunant Hospital Center,2nd Neurological Department, Athens, Not set
Aiginitio Hospital, 1st Neurology Clinic, Athens, Not set
"Hygeia" General Hospital of Athens, Memory clinic, Athens, Not set
Naval Hospital of Athens, Athens, Not set
Aiginitio Hospital, 1st Neurology Clinic, Athens, Not set
University General Hospital of Athens "Attiko", Chaidari, Athens, Not set
AHEPA General University Hospital, Thessaloniki, Not set
EUROMEDICA General Clinic of Thessaloniki,Neurology Dpt, Thessaloniki, Not set
Clinexpert Egészségügyi Szolgáltató és Kereskedelmi Kft., Budapest, Not set
Semmelweis Egyetem ÁOK, Budapest, Not set
DE Kenézy Gyula Campus, Pszichiátriai és Pszichoterápiai Klinika, Debrecen, Not set
DE Gyógyszerfejlesztési Koordinációs Központ Pszichiátria, Debrecen, Not set
Petz Aladar Megyei Korhaz, Gyor, Not set
Petz Aladar Megyei Oktato Korhaz, Gyor, Not set
Bugát Pál Kórház, Gyöngyös, Not set
Somogy Megyei Kaposi Mór Oktató Kórház, Kaposvár, Not set
Psychotech Kft., Pécs, Not set
Belvárosi Egészségház Kft., Zalaegerszeg, Not set
St Vincent's University Hospital, Dublin, Not set
Mercer's Institute for Successful Aging, Dublin, Not set
Tallaght University Hospital, Dublin, Not set
The Stroke and Cognition Institute Rambam Medical Center, Haifa, Not set
Cognitive Neurology Clinic, Rabin Campus, Beilinson Hospital, Petach Tikva, Not set
Cognitive Neurology Sourasky Medical Center, Tel Aviv, Not set
Chaim Sheba Medical Center, Heart Screening Clinic, 1st floor, Room 317, Tel Hashomer, Ramat Gan, Not set
AOU Ospedali Riuniti S.O.D, Ancona, Not set
Azienda Ospedaliera Spedali Civili di Brescia, Brescia, Not set
Università degli studi Gabriele D'Annunzio Chieti-Pescara, Chieti, Not set
AOU Careggi Firenze, Firenze, Not set
Fondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, Milano, Not set
IRCCS Ospedale San Raffaele Milano, Milano, Not set
ASST Monza e Brianza Ospedale San Gerardo, Monza, Not set
Ospedale Santa Maria della Misericordia, Perugia, Not set
Pol. Uni. Campus Biomedico UOC Neurologia, Roma, Not set
Policlinico Tor Vergata, Roma, Not set
Policlinico Universitario A.Gemelli Servizio Neuropsicologia, Roma, Not set
Fondazione Santa Lucia IRCCS, Roma, Not set
AOU Città della Salute e della Scienza di Torino, Torino, Not set
Iwaki Clinic_Psychosomatic medicine, Anan, Tokushima, Not set
Memory Clinic Ochanomizu, Bunkyo-ku, Tokyo, Not set
Tokyo Medical And Dental University Hospital, Bunkyo-ku,Tokyo, Not set
Kashiwado Hospital, Chib-shi, Chiba, Not set
Enomoto Internal Medicine Clinic, Chofu-shi,Tokyo, Not set
Shinozuka Hospital, Fujioka-Shi, Gunma, Not set
P-one Clinic, Hachioji-shi, Tokyo, Not set
National Hospital Organization Tenryu Hospital, Hamamatsu-shi, Shizuoka, Not set
Hyogo Brain and Heart Center, Himeji-city, Hyogo, Not set
Tsukazaki Hospital, Himeji-shi, Hyogo, Not set
Himeji Central Hospital Clinic, Himeji-shi, Hyogo, Not set
Hatsuta Neurology Clinic, Hirakata-Shi,Osaka, Not set
Imon Yukari Neurology Clinic, Hiroshima-shi, Hiroshima, Not set
Hikaru-kai Medical Corporation Hiroshima Neurology Clinic, Hiroshima-shi, Hiroshima, Not set
Hiroshima Neurology Clinic, Hiroshima-shi, Hiroshima, Not set
Nagamitsu Clinic, Hofu-shi, Yamaguchi, Not set
Ina Central Hospital, Ina-shi, Nagano, Not set
Kawasaki Saiwai Clinic_Internal Medicine, Kanagawa, Not set
Kishiro Mental Clinic, Kawasaki-shi , Kanagawa, Not set
Koukan Clinic, Kawasaki-shi, Kanagawa, Not set
Teikyo University Hospital, Mizonokuchi_Kawasaki-shi, Kanagawa, Kawasaki-shi, Kanagawa, Not set
Kobe University Hospital_Kobe-shi, Hyogo, Kobe-shi, Hyogo, Not set
National Center of Neurology and Psychiatry, Kodaira-shi, Tokyo, Not set
Southern Tohoku Medical Clinic, Koriyama-shi, Fukushima, Not set
Katayama Medical Clinic, Kurashiki-shi, Okayama, Not set
Nozomi Memory Clinic, Mitaka-shi,Tokyo, Not set
Kikukawa clinic, Nerima-ku, Tokyo, Not set
General Rehabilitation Center · Midori Hospital, Niigata-shi, Niigata, Not set
National Center for Geriatrics and Gerontology, Obu-shi, Aichi, Not set
Jichiidai Station Brain Clinic, Shimotsuke-shi, Tochigi, Not set
Keio University Hospital, Shinjuku-ku, Tokyo, Not set
Kagawa Prefectural Central Hospital_Takamatsu-shi, Kagawa, Takamatsu-shi, Kagawa, Not set
Takatsuki General Hospital, Takatsuki-Shi, Osaka, Not set
Saino Clinic, Tokorozawa-shi,Saitama, Not set
Itsuki Hospital, Tokushima-shi, Tokushima, Not set
Alzclinic Tokyo, Tokyo, Not set
Tokyo Center Clinic, Tokyo, Not set
Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Not set
Kurumi CLINIC, Tokyo, Not set
Tokyo Medical Univ. Hospital, Tokyo, Not set
Memory Clinic Toride, Toride-shi, Ibaraki, Not set
MI Clinic, Toyonaka-shi, Osaka, Not set
Medical Corporation Midorikai Wako Hospital, Wako-shi, Saitama, Not set
Dong-A University Medical Center, Busan, Not set
Chungnam National University Hospital, Daejeon, Not set
Chonnam National University Hospital, Gwangju, Not set
Seoul National University Bundang Hospital, Gyeonggi-do, Not set
Gachon University Gil Medical Center, Incheon, Not set
Inha University Hospital, Incheon, Not set
Hanyang University Medical Center, Seoul, Not set
Hanyang university seoul hospital, Seoul, Not set
Konkuk University Medical Center, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center_Seoul, Seoul, Not set
Ewha Womans University Seoul Hospital, Seoul, Not set
Amphia Ziekenhuis, Breda, Not set
Brain Research Center, Den Bosch, Not set
Radboudumc, Nijmegen, Not set
Linden sp. z o.o. sp. k., Kraków, Małopolskie
Centrum Medyczne Neuromed, Bydgoszcz, Not set
Centrum Zdrowia Psychicznego Biomed, Kielce, Not set
Szpital Uniwersytecki w Krakowie od. Neurologii, Kraków, Not set
Centrum Neurologii Klinicznej, Kraków, Not set
Nzoz Neuromed, Lublin, Not set
INSTYTUT ZDROWIA DR BOCZARSKA-JEDYNAKSp. z o.o. Sp. k., Oswiecim, Not set
NZOZ NEURO - KARD Ilkowski i Partnerzy Sp. Part. Lekarzy, Poznan, Not set
Osrodek Alzheimerowski Sp. z o.o., Scinawa, Not set
Centrum Medyczne SENIOR, Sopot, Not set
Centrum Medyczne Neuro Protect, Warszawa, Not set
NZOZ Wrocławskie Centrum Alzheimerowskie, Wroclaw, Not set
Unidade Local De Saude De Matosinhos E.P.E., Senhora Da Hora, Matosinhos, Matosinhos
Hospital de Braga, Braga, Not set
Unidade Local de Saúde de Coimbra, E.P.E., Coimbra, Not set
Unidade Local de Saude do Alto Ave, E.P.E., Guimarães, Not set
Unidade Local De Saude De Lisboa Ocidental E.P.E. - Hospital Egas Moniz, Lisboa, Not set
Hospital Beatriz Ângelo, Loures, Not set
Unidade Local de Saúde de Santo António, E.P.E, Porto, Not set
Campus Neurologico Senior, Torres Vedras, Not set
Spitalul Clinic Cai Ferate Constanta, Constanta, Not set
Spitalul Clinic Judetean De Urgenta Sfantul Apostol Andrei Constanta, Constanta, Not set
Aria Clinic SRL, Sibiu, Not set
SAHI SR "Sverdlovsk Regional Clinical Psychiatric Hospital", Ekaterinburg, Not set
Joint Stock Company "Medical technologies", Ekaterinburg, Not set
FSAEI 1st Moscow Federal Med University na Sechenov, Moscow, Not set
RMAPE, Moscow, Not set
Pirogov Russian National Research Medical University MoH, Moscow, Not set
Ezramed Clinic Llc, Omsk, Not set
Research Center for Treatment and Rehabilitation "Phoenix", Rostov-on-Don, Not set
Psychiatric hospital of st. Nicholas the wonderworker, Saint Petersburg, Not set
N.-E. State Medical University n.a. Mechnikov, Saint Petersburg, Not set
Center of Clinica Trials "Nebbiolo", Tomsk, Not set
LLC "Clinic Stolet", Tomsk, Not set
National medical holdiNational medical holding "Medstandard", Ufa, Not set
Neurology clinic, University Clinical Center of Serbia, Belgrade, Not set
Special Hospital for Psychiatric Disorders "Kovin", Kovin, Not set
University clinical center of Vojvodina, Neurology clinic, Novi Sad, Not set
I. neurologicka klinika LF UK a UNB, Bratislava, Not set
Psychiatricka klinika LF UK a UNB, Bratislava, Not set
Neurologicka klinika UPJS LF a UNLP, Kosice, Not set
NEURES, neurologicka ambulancia, Krompachy, Not set
Crystal Comfort s.r.o., Vranov nad Toplou, Not set
UKC Ljubljana, Department of Neurology, Ljubljana, Not set
UKC Maribor - neurology, Maribor, Not set
Excellentis Clinical Trial Consultants, George, Eastern Cape
IATROS International, Bloemfontein, Free State
Dr Stanley Lipschitz Clinic Inc, Johannesburg, Gauteng
Denmar Psychiatric Hospital, Pretoria, Gauteng
ACF Neurological service, Cape Town, Western Cape
Flexivest Fourteen Research Centre, Cape Town, Western Cape
Cape Trial Centre, Cape Town, Western Cape
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Fundación ACE, Barcelona, Not set
Hospital 12 de Octubre, Madrid, Not set
Hospital Universitario Quirónsalud Madrid, Pozuelo de Alarcon, Not set
Hospital Universitari General de Catalunya, Sant Cugat del Vallès, Not set
Hospital Universitario Doctor Peset, Valencia, Not set
Minnesmottagning specialiserad Malmö, Malmö, Not set
Karolinska Universitetssjukhuset, Huddinge, Stockholm, Not set
Geriatriskt centrum, Umeå, Umeå, Not set
Spitalzentrum Biel, Biel-Bienne, Not set
Centre de la Mémoire, Genève, Not set
Centre Leenaards de la mémoire CHUV, Lausanne, Not set
Klinik für Neurologie Kantonsspital St.Gallen, St. Gallen, Not set
Chang Gung Memorial Hospital - Kaoshiung Branch, Kaohsiung City, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set
Chang Gung Memorial Hospital - Kaoshiung Branch, Kaohsiung, Not set
China Medical University Hospital, Taichung, Not set
National Cheng Kung University Hospital, Tainan City, Not set
National Cheng Kung University Hospital, Tainan, Not set
National Taiwan University Hospital_main, Taipei, Not set
Taipei Veteran General Hospital_Dept of Neurology, Taipei, Not set
Taipei Veteran General Hospital, Taipei, Not set
Chang Gung Memorial Hospital Linkou, Taoyuan City, Not set
Chang Gung Memorial Hospital, Linkou, Taoyuan, Not set
Hacettepe University Medical Faculty Hospital, Altindag/Ankara, Not set
Eskisehir Osmangazi University Sağlık Uygulama ve Arastirma, Eskisehir, Not set
Istanbul University Medical Faculty Neurology Department, Istanbul, Not set
Izmir Economics University Medical Point Hospital Neurology D, Izmir, Not set
Ondokuz Mayis University Saglik Uygulama ve Arastirma Merkez, Samsun, Not set
Medical Center 'Neiron', Kharkiv, Not set
Odesa Regional Medical Center for Mental Health, Odesa, Not set
Fritchie Centre, Cheltenham, Gloucestershire
Royal Cornhill Hospital, Aberdeen, Not set
RICE - The Research Institute for the Care of Older People, Bath, Not set
Dementia Research Unit,, Crowborough, Not set
Dementia Research Unit, Crowborough, Not set
Ninewells Hospital, Dundee, Not set
Western General Hospital, Edinburgh, Not set
St Pancras Clinical Research, London, Not set
St George's Hospital, London, Not set
Imperial College London - Imperial College Memory Research Centre, London, Not set
Greater Manchester Mental Health NHS Foundation Trust, Manchester, Not set
NeuroClin, Motherwell, Not set
Newcastle University, Newcastle Upon Tyne, Not set
Warneford Hospital, Oxford, Not set
Moorgreen Hospital, Southampton, Not set
Kings Hill Research Centre, Swindon, Not set
Conditions: Early Alzheimer´s Disease
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes
Active Not Recruiting
This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medicine). The study will be performed in people with type 2 diabetes. Participants will either get semaglutide or placebo in addition to their diabetes medicines - which treatment the participant gets is decided by chance. Participants will inject the study medicine using a pen-injector. The medicine must be injected in a skin fold in the stomach, thigh or upper... Read More
This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medicine). The study will be performed in people with type 2 diabetes. Participants will either get semaglutide or placebo in addition to their diabetes medicines - which treatment the participant gets is decided by chance. Participants will inject the study medicine using a pen-injector. The medicine must be injected in a skin fold in the stomach, thigh or upper arm once a week. The study will last for 5 years. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2025
Locations: Del Sol Research Management, LLC, Tucson, Arizona +180 locations
Del Sol Research Management, LLC, Tucson, Arizona
Southern California Res Ctr, Coronado, California
FDRC, Costa Mesa, California
Diabetes/Lipid Mgmt & Res Ctr, Huntington Beach, California
Scripps Whittier Diabetes Inst, La Jolla, California
Torrance Clin Res Inst, Inc., Lomita, California
Downtown LA Res Ctr. Inc., Los Angeles, California
Rancho Cucamonga Clinical Research, Rancho Cucamonga, California
Clinical Trials Research_Sacramento_0, Sacramento, California
Coastal Metabolic Research Center, Ventura, California
Diablo Clinical Research, Inc., Walnut Creek, California
Barbara Davis Center, Aurora, Colorado
Rocky Mount Reg VA Med-DN, Aurora, Colorado
Chase Medical Research LLC, Waterbury, Connecticut
Innovative Research of W FL, Clearwater, Florida
Est Cst Inst for Rsrch,Jksnvil, Jacksonville, Florida
Renstar Medical Research, Ocala, Florida
Atlanta Diabetes Associates, Atlanta, Georgia
Endo Res Solutions Inc, Roswell, Georgia
Apex Medical Research Inc, Chicago, Illinois
The University Of Chicago, Chicago, Illinois
American Health Network of Indiana, LLC_Avon, Avon, Indiana
Iowa Diab & Endo Res Center, West Des Moines, Iowa
Kentucky Diabetes-Endocrinology Center, Lexington, Kentucky
The Research Group of Lexington LLC, Lexington, Kentucky
L-MARC Research Center, Louisville, Kentucky
Four Rivers Clinical Research Inc, Paducah, Kentucky
Brigham & Women's Hospital, Boston, Massachusetts
Boston Medical Center_Cary, Boston, Massachusetts
Joslin Center For Diabetes, Boston, Massachusetts
Joslin Diabetes Center, Boston, Massachusetts
Michigan Medicine, Ann Arbor, Michigan
University of New Mexico, Albuquerque, New Mexico
NYC Research, Inc., New York, New York
Mountain Diabetes & Endocrine Center, Asheville, North Carolina
OnSite Clinical Solutions, LLC, Charlotte, North Carolina
Harold Hamm Diabetes Center, Oklahoma City, Oklahoma
Tristar Clin Investigations, PC, Philadelphia, Pennsylvania
Holston Medical Group Pc, Bristol, Tennessee
Univ Diab & Endo Consultants, Chattanooga, Tennessee
Holston Medical Group, Kingsport, Tennessee
Vanderbilt Diab Obes Clin Tri, Nashville, Tennessee
Central Texas Clinical Research, Austin, Texas
Texas Diab & Endo, P.A., Austin, Texas
Velocity Clinical Res-Dallas, Dallas, Texas
UT Southwestern Med Cntr, Dallas, Texas
Clinical Trials of Texas, LLC, San Antonio, Texas
VIP Trials, San Antonio, Texas
Consano Clinical Research, LLC, Shavano Park, Texas
Simcare Medical Research, LLC, Sugar Land, Texas
MultiCare Inst for Res & Innov, Spokane, Washington
CPQuali Pesquisa Clínica Ltda, São Paulo, Sao Paulo
DCC I- Pleven EOOD, Pleven, Not set
MHAT Sveti Pantaleimon - Pleven, Internal Diseases, Pleven, Not set
MHAT "Med Line Clinic", Plovdiv, Not set
UMHAT "Sveti Georgi", Clinic of Endocr. and Metab. Diseases, Plovdiv, Not set
MHAT MC-Sv Ivan Rilski EOOD, Plovdiv, Not set
"DCC VII - Sofia", Endocrinology Consulting Room, Sofia, Not set
MHAT "Knyaginya Klementina" -Sofia EAD, Sofia, Not set
USHATE "Akad. Ivan Penchev" Second Clinic of Endocrinology, Sofia, Not set
"Fourth MHAT-Sofia EAD", Sofia, Not set
"DCC XX - Sofia" EOOD, Endocrinology Consulting Room, Sofia, Not set
Medical centre Vitclinic EOOD, Sofia, Not set
Alberta Diabetes Institute, Edmonton, Alberta
LMC Clinical Res Thornhill, Concord, Ontario
LMC Endo Ctr (Etobicoke) Ltd, Etobicoke, Ontario
LMC Endo Centres Ltd.(Bayview), Toronto, Ontario
Centricity Res Pointe-Claire, Pointe-Claire, Quebec
LMC Clin Rsrch Inc. (Montreal), Saint-Laurent, Quebec
Fakultni nemocnice Brno, Brno, Not set
Fakultni nemocnice Hradec Kralove, Hradec Kralove, Not set
Diabetologie Krupska, Praha 10, Not set
Institut klinicke a experimentalni mediciny, Praha 4, Not set
MUDr. Michala Pelikanova, Praha 4, Not set
Fakultni nemocnice Kralovske Vinohrady_Praha, Praha, Not set
Praxis Denger/Pfitzner, Friedrichsthal, Friedrichsthal, Not set
Diabetes-Zentrum-Wilhelmsburg GbR, Hamburg, Not set
Wendisch/Dahl Hamburg (DZHW), Hamburg, Not set
Wendisch/Dahl Hamburg, Hamburg, Not set
Institut für Diabetesforschung GmbH Münster - Dr. med. Rose, Münster, Not set
MedicalCenter am Clemenshospital - Schwerpunktpraxis für Diabetologie und Ernährungsmedizin, Münster, Not set
Praxis Dr. med. Wenzl-Bauer, Rehlingen-Siersburg, Not set
Zentrum für klinische Studien Alexander Segner, Saint Ingbert-Oberwürzbach, Not set
University Hospital of Athens ATTIKON, Athens, Attica
Iatriko Psychicou Private Clinic, Athens, Not set
"Laiko" General Hospital of Athens, Athens, Not set
"Laiko" General Hospital of Athens, Athens, Not set
Iatriko Athinon 'Palaiou Falirou', Athens, Not set
University Hospital of Athens ATTIKON, Haidari-Athens, Not set
"Ippokrateio" G.H. of Thessaloniki, Thessaloniki, Not set
"Thermi" Private Hosital, Thessaloniki, Not set
"Thermi" Private Hosital, Thessaloniki, Not set
Endolife Specialty Hospitals, Guntur, Andhra Pradesh
Narayana Hrudayalya Institute of Cardiac Sciences, Bangalore, Karnataka
Diacon Hospital Private Limited, Bangalore, Karnataka
Amrita Institute Of Medical Sciences & Research Centre, Kochi, Kerala
Indian Institute of Diabetes, Thiruvananthapuram, Kerala
BYL Nair Hospital and T N Medical College Department of endo, Mumbai, Maharashtra
Government Medical College and Super Speciality Hospital, Nagpur, Nagpur, Maharashtra
Deenanath Mangeshkar Hospital & Research Centre, Pune, Maharashtra
All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, New Delhi
Apollo Hospital, Delhi, New Delhi
Indraprastha Apollo Hospital, Delhi, New Delhi
All India Institute of Medical Sciences, New Dehli, New Delhi
Christian Medical College and Hospital, Ludhiana, Punjab
Madras Diabetes Research Foundation, Chennai, Tamil Nadu
Arthur Asirvatham hospital,, Madurai, Tamil Nadu
Apollo Gleneagles Hospital, Kolkata, West Bengal
Care Hospital, Hyderabad, Not set
Diabetes and obesity center of excellence, Rambam MC, Haifa, Not set
Diabetes Unit Hadassah Ein Karem MC, Jerusalem, Not set
Clinical Research Unit Meir Medical Center, Kfar Saba, Not set
Rabin MC Beilinson Campus Endo, Petah-Tikva, Not set
Endrocrinolgy Clinic - Sheba Medical Center, Tel Hashomer, Not set
Institute of Endocrinology, metabolism and hypertension, Tel-Aviv, Not set
Zemgales diabetes centre, Jelgava, Not set
Teterovska practice, Ogre, Not set
Medical Centre Pulss 5, Riga, Not set
P. Stradins Clinical University Hospital, Riga, Not set
Juglas Medicine Center, Riga, Not set
Instituto Nacional de Nutricion - Unidad de Inv de Enf Metab, Distrito Federal, México, D.F.
Hospital Universitario Dr. José Eleuterio González_Monterrey, Monterrey, Nuevo León
Uniwersytecki Szpital Kliniczny w Bialymstoku, Bialystok, Podlaskie Voivodeship
Santa Sp. z o.o, Santa Familia Centrum Badan, Profilaktyki i Leczenia, Lodz, Wojewodztwo Lodzkie
In-Vivo Sp. z o.o., Bydgoszcz, Not set
B_Serwis Popenda Sp.J., Chorzow, Not set
Synexus Polska Sp. z o.o. Oddzial w Gdansku, Gdansk, Not set
NZOZ Gdanska Poradnia Cukrzycowa Sp.z o.o., Gdansk, Not set
Centrum Medyczne Pratia Katowice, Katowice, Not set
FutureMeds Sp. z o.o., Kraków, Not set
Santa Sp. z o.o, Santa Familia Centrum Badan, Profilaktyki i Leczenia, Lodz, Not set
Prywatny Gabinet Lekarski Jan Ruxer, Lodz, Not set
NZOZ "DiabMed" Poradnia Diabetologiczna, Poznan, Not set
Gaja Poradnie Lekarskie, Poznan, Not set
SPSK nr 1 im. prof. Stanisława Szyszko Śląskiego Uniwersytetu Medycznego w Katowicach, ul. 3-go Maja 13/15 41-800 Zabrze, Zabrze, Not set
Unidade Local De Saude De Matosinhos E.P.E., Senhora Da Hora, Matosinhos, Matosinhos
Unidade Local De Saude De Almada-Seixal E.P.E., Almada, Not set
Unidade Local De Saude Da Regiao De Aveiro E.P.E., Aveiro, Not set
Unidade Local de Saúde de Coimbra, E.P.E., Coimbra, Not set
Unidade Local de Saude do Alto Ave, E.P.E., Guimarães, Not set
APDP - Associação Protectora dos Diabéticos de Portugal, Lisboa, Not set
Centro Hospitalar de São João, Porto, Not set
Unidade Local de Saude de Sao Joao E.P.E, Porto, Not set
Unidade Local de Saúde da Arrábida, E.P.E., Setubal, Not set
Institutul National De Diabet Nutritie Si Boli Metabolice Prof.Dr.N.Paulescu Bucuresti- Ion Movila, Bucharest, Bucurestii
Clinic of Diabetes Cluj, Cluj Napoca, Cluj
3rd Clinic for Nutrition-Spitalulul Județean de Urgenta, Timisoara, Timis
"Carol Davila" Military Emergency Hospital, Bucharest, Not set
Sana Monitoring SRL, Bucharest, Not set
SC Clinica Diabnutrimed S.R.L., Bucharest, Not set
Multispecialty Medical Clinic Anturium LLC, Barnaul, Not set
Kazan Federal University, Kazan, Not set
PIH "Clin Hosp "RZD-Medicina" former Kazan OJSC Rus Railways, Kazan, Not set
National Medical Research Center of Endocrinology, Moscow, Not set
City Consultative & Diagnostic Centre #1, Saint-Petersburg, Not set
Diagnistic Centre "Energo", Saint-Petersburg, Not set
Consultative & Diagnostic Center with a Outpatient Hospital, Saint-Petersburg, Not set
SHI Saratov City Clinical Hospital #9, Saratov, Not set
Regional clinical cardiology dispensary, Saratov, Not set
CHC Zvezdara, Clinical department for endocrinology, Belgrade, Not set
Endocrinology, Diabetes and Metabolism Diseases Clinic, Belgrade, Not set
Clinical Hospital Center Bezanijska Kosa, Belgrade, Not set
Clinical Centre Nis, Endocrinology, Diabetes and Metabolism, Nis, Not set
Nemocnica akademika L. Derera, UNB, Bratislava, Not set
Diabetologicka ambulancia, Dia Zilina s.r.o., Zilina, Not set
Medivasa s.r.o., Diabetologicka ambulancia, Zilina, Not set
MEDIVASA, s.r.o., Diabetologicka ambulancia, Zilina, Not set
Hospital Vall d'Hebron, Barcelona, Not set
Hospital de Bellvitge, Hospitalet de Llobregat, Not set
Complejo Hospitalario Universitario A Coruña, La Coruña, Not set
Clinica Universitaria de Navarra, Pamplona, Not set
Hospital Virgen de la Macarena, Sevilla, Not set
Hospital La Fe - Endocrinología y Nutrición, Valencia, Not set
Harrogate District Hospital, Harrogate, North Yorkshire
University Hospital, Queens Medical Centre, Nottingham, Nottinghamshire
Yeovil District Hospital - Clinical Research Unit, Yeovil, Somerset
Kings College Hospital, London, Not set
The Norfolk and Norwich University Hospital, Norfolk, Not set
George Eliot Hospital NHS Trust, Nuneaton, Not set
Clinical Research Unit, Somerset, Not set
Royal Cornwall Hospital (Treliske), Truro, Not set
Conditions: Diabetes Mellitus, Type 2
A Research Study to Find Out How Semaglutide Works in the Kidneys Compared to Placebo, in People With Type 2 Diabetes and Chronic Kidney Disease (the REMODEL Trial)
Completed
We are doing this study to learn more about how semaglutide may help fight chronic kidney disease in people with type 2 diabetes. We are doing this by looking into how semaglutide works in the kidneys.
Participants will either get semaglutide or placebo (a 'dummy' medicine) - which treatment participants get is decided by chance.
Semaglutide is a medicine doctors can prescribe in some countries for the treatment of type 2 diabetes.
Participants will get the study medicine in a pen. Participan... Read More
We are doing this study to learn more about how semaglutide may help fight chronic kidney disease in people with type 2 diabetes. We are doing this by looking into how semaglutide works in the kidneys.
Participants will either get semaglutide or placebo (a 'dummy' medicine) - which treatment participants get is decided by chance.
Semaglutide is a medicine doctors can prescribe in some countries for the treatment of type 2 diabetes.
Participants will get the study medicine in a pen. Participants will use the pen to inject the medicine into the skin once a week.
The study will last for about 1 year. Participants will have 11 visits to the clinic, and 2 phone visits. Some of the visits could be in different locations.
Study staff will take blood samples at most of these visits. At 9 visits, participants will be asked to bring a sample of their first morning urine. At 4 of the visits participants will have to bring urine that they have collected over the last 24 hours.
The study includes magnetic resonance imaging (MRI) scans of participants' kidneys which is a test that shows a detailed picture of organs and other parts inside the body. The scan will last for 30 minutes, and is free of radiation. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2025
Locations: Academic Medical Research Institute, Los Angeles, California +30 locations
Academic Medical Research Institute, Los Angeles, California
N America Res Inst - San Dimas, San Dimas, California
UC Anschutz Medical Campus, Aurora, Colorado
Advent Health-Res Inst, Orlando, Florida
Clinical Research Consultants, LLC, Kansas City, Missouri
Prolato Clinical Research Cntr, Houston, Texas
NE Clin Res of San Antonio, San Antonio, Texas
Univ of Washington Med Ctr, Seattle, Washington
Providence Medical Research Center, Spokane, Washington
UHN-Toronto General Hospital, Toronto, Ontario
Nefrologisk Klinik P 2132, Copenhagen, Not set
Steno Diabetes Center Copenhagen, Herlev, Not set
Centre Hospitalier Universitaire Amiens Picardie-Site Sud, AMIENS cedex 1, Not set
Centre Hospitalier Universitaire de Rouen - Hopital de Bois Guillaume, Bois-Guillaume, Not set
Centre Hospitalier Universitaire Grenoble Alpes-Site Nord Michallon-2, Grenoble - Cédex 09, Not set
Centre Hospitalier Universitaire Reims-Hopital Maison Blanche, Reims, Not set
Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-1, Toulouse, Not set
Istituto Scientifico San Raffaele, Milano, MI
Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Not set
Azienda Ospedaliera di Padova Clin.Med.3, Padova, Not set
Azienda Ospedaliero - Universitaria Sant'Andrea, Roma, Not set
Centrum Medyczne "Diabetika", Radom, Not set
SPSK nr 2 PUM, Kl. Nefrologii, Transplantologii i Ch. Wewn., Szczecin, Not set
Miedzyleski Szpital Specjalistyczny, Oddzial Nefrologiczny, Warszawa, Not set
Prywatny Gabinet Janusz Gumprecht, Zabrze, Not set
Maxwell Centre, Durban, KwaZulu-Natal
Precise Clinical Solutions (Pty) Ltd, Durban, KwaZulu-Natal
Prof Rayner_Division of Nephrology, Cape Town, Western Cape
Hospital Vall d'Hebron, Barcelona, Not set
Hospital de Bellvitge, Hospitalet de Llobregat, Not set
Hospital Clínico Universitario de Valencia, Valencia, Not set
Conditions: Diabetes Mellitus, Type 2, Chronic Kidney Disease
Research Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non-alcoholic Steatohepatitis (NASH)
Completed
This study is being done to see if a combination of 2 medicines (called NNC0194-0499 and semaglutide) can reduce liver damage in patients with non alcoholic steatohepatitis (NASH).
NNC0194-0499 is a new medicine which works in the liver. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. It also helps with weight loss and may reduce liver damage, and so prevent future liver complications. It works in a different way to NNC0194 0499... Read More
This study is being done to see if a combination of 2 medicines (called NNC0194-0499 and semaglutide) can reduce liver damage in patients with non alcoholic steatohepatitis (NASH).
NNC0194-0499 is a new medicine which works in the liver. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. It also helps with weight loss and may reduce liver damage, and so prevent future liver complications. It works in a different way to NNC0194 0499. The 2 medicines may work better together than on their own.
The study will also look at a combination of semaglutide and another weight-loss medicine called NNC0174-0833, which may be another treatment option for NASH.
Each week, participants will get 2 injections. These could be 2 of the 3 medicines OR 1 of the medicines and a placebo OR 2 placebo injections. Which treatment participants get is decided by chance. A placebo is a dummy medicine which looks like the real medicine but doesn't contain any active medicine.
The study will last for about 19 months. Participants will have 14 clinic visits and 9 phone calls with the study doctor.
Participants will have 1 or 2 liver biopsies (tiny pieces of liver tissue) - one at the start (if participants have not had a biopsy recently) and one at the end of the study treatment.
Women: Women cannot take part if pregnant, breast-feeding or planning to become pregnant during the study period. Read Less
Gender:
ALL
Ages:
All
Trial Updated:
06/17/2025
Locations: North AL Health Res, LLC, Huntsville, Alabama +183 locations
North AL Health Res, LLC, Huntsville, Alabama
The Institute for Liver Health, Chandler, Arizona
Inst-Liver Hlth dba AZ Liver H, Peoria, Arizona
Del Sol Research Management, LLC, Tucson, Arizona
UCSD NAFLD Research Center, La Jolla, California
OM Research LLC, Lancaster, California
Stanford Medicine, Redwood City, California
UC Davis Hlth -Midtwn Ambu Cen, Sacramento, California
Peak Gastro Assoc-Col Springs, Colorado Springs, Colorado
Hartford Hsptl_Hartford, Hartford, Connecticut
Integrity Clinical Research, LLC, Doral, Florida
Miguel Rebollar PA, Hialeah, Florida
Nature Coast Clinical Research_Inverness, Inverness, Florida
UF Hlth Jacksonville, Jacksonville, Florida
Florida Research Institute, LLC, Lakewood Ranch, Florida
Optimus U, Corp, Miami, Florida
Univ of Miami/Schiff Ctr, Miami, Florida
Covenant Metabolic Specialists LLC, University Park, Florida
Florida Medical Clinic Orlando Health, Zephyrhills, Florida
Florida Medical Clinic, LLC, Zephyrhills, Florida
Piedmont Healthcare, Atlanta, Georgia
Digestive Healthcare of Georgia, Atlanta, Georgia
Gastroenterology Assoc_ CGA, Macon, Georgia
Gastroint Spec of Georgia, Marietta, Georgia
Digestive Research Alliance of Michiana, South Bend, Indiana
University Of Kansas Hospital, Kansas City, Kansas
Kansas Medical Clinic, PA, Topeka, Kansas
Tandem Clinical Research - Houma, Houma, Louisiana
Tandem Clinical Research, Marrero, Louisiana
Louisiana Research Center, LLC, Shreveport, Louisiana
Mercy Medical Center, GI Research, Baltimore, Maryland
Walter Reed Nat Mil Md Ctr, Bethesda, Maryland
Henry Ford Hospital_Detroit, Detroit, Michigan
Kansas City Research Institute, Kansas City, Missouri
AIG Digestive Disease Research, Florham Park, New Jersey
NYU Grossman School of Med, New York, New York
Weill Cornell Med Coll-NYPH, New York, New York
Univ Hosp Cleveland Med Ctr, Cleveland, Ohio
Ohio State Univ Wexner Med Ctr, Columbus, Ohio
DSI Research,LLC, Springboro, Ohio
Geisinger Clinic, Danville, Pennsylvania
Pennsylvania State University, Hershey, Pennsylvania
University of Pennsylvania Hospital, Philadelphia, Pennsylvania
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
UPMC Center for Liver Diseases, Pittsburgh, Pennsylvania
UPMC_Center for Liver Care, Pittsburgh, Pennsylvania
Digestive Health Res-TSMC, Hermitage, Tennessee
Quality Medical Research, Nashville, Tennessee
Texas Clin Res Inst, LLC, Arlington, Texas
Liver Ins@ Mthdist DTX Med Cen, Dallas, Texas
Texas Diabetes &Endocrinology, Round Rock, Texas
Amer. Rrsch Corp-TX Liver Inst, San Antonio, Texas
Olympus Clinical Research, Sugar Land, Texas
Impact Research, Waco, Texas
Digestive Hlth Res of N Texas, Wichita Falls, Texas
Inova Fairfax Medical Campus, Falls Church, Virginia
Bon Secours Richmond Community Hospital LLC, Richmond, Virginia
Gastroent Consult of SW VA, Roanoke, Virginia
Swedish med ctr org trans-lvr ctr, Seattle, Washington
Liver Institute NW, Seattle, Washington
Genesis Research Services, Broadmeadow, New South Wales
St Vincent's Hospital, Darlinghurst, New South Wales
Nepean Hospital, Kingswood, New South Wales
Westmead Hospital, Westmead, New South Wales
Royal Adelaide Hospital - Hepatology- 5E291, Adelaide, South Australia
Monash Health Department of Gastroenterology, Clayton, Victoria
St Vincent's Hospital (Melbourne), Fitzroy, Victoria
Austin Health, Heidelberg, Victoria
The Alfred Centre - Gastroenterology, Melbourne, Victoria
Fiona Stanley Hospital - Hepatology, Murdoch, Western Australia
CUB Hôpital Erasme_Brussels_0, Bruxelles, Not set
Cliniques Universitaires Saint-Luc - Serv. Hépato-gastroentérology, Bruxelles, Not set
UZA, Edegem, Not set
UZ Gent - Department Gastro-enterology, Gent, Not set
"Acibadem City Clinic UMHAT Tokuda", Sofia, Not set
UMHAT "Sv. Ivan Rilski", Clinic of Gastroenterology, Sofia, Not set
"DCC XX - Sofia" EOOD, Sofia, Not set
University of Calgary Liver Unit-(HMRC), Calgary, Alberta
GI Research Inst Foundation, Vancouver, British Columbia
Toronto Liver Centre, Toronto, Ontario
Krajská nemocice Liberec, a.s, Liberec, Not set
Hvidovre Hospital - Gastroenheden, Hvidovre, Not set
Abdominal Center K, Research Unit, København NV, Not set
Odense University Hospital, Odense C, Not set
Centre Hospitalier Universitaire D'Angers-1, Angers, Not set
Ap-Hp-Hopital Beaujon, Clichy, Not set
Hospices Civils de Lyon-Hopital de La Croix Rousse, Lyon Cedex 4, Not set
Centre Hospitalier Universitaire de Nice-Hopital de L'Archet 2, Nice, Not set
Aphp-Hopital La Pitie Salpetriere-4, Paris, Not set
Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec-1, Saint Herblain, Not set
Centre de Recherche Clinique Portes Du Sud, Venissieux, Not set
Klinik für Endokrinologie, Diabetologie und Stoffwechsel, Essen, Not set
Universitätsklinikum Schleswig-Holstein - Medizinischen Klinik I am Campus Lübeck, Lübeck, Not set
Universitätsklinikum Schleswig-Holstein, Lübeck, Not set
Universitätsmedizin der Johannes-Gutenberg-Universität Mainz - Hepatologie, Mainz, Not set
Universitätsklinikum Würzburg, Zentrum für Innere Medizin (ZIM), Würzburg, Not set
Universitätsklinikum Würzburg, ZIM, Würzburg, Not set
Gen Hospital of Athens Ippokrateio,B' Uni Clinic of Inte Med, Athens, Not set
Gen Hospital of Athens Laiko,1st Dpt. of Propaedeutic Inter, Athens, Not set
Gen Hospital of Athens Laiko,1st Dpt. of Propaedeutic Inter, Athens, Not set
General Hospital of Athens "LAIKO", Goudi, Athens, Not set
"AHEPA" University Hospital of Thessaloniki, Thessaloniki, Not set
General Hospital of Thessaloniki "Ippokrateio", Thessaloniki, Not set
Yashoda Hospital, Secunderabad, Andhra Pradesh
Surat Institute of Digestive Science, Surat, Gujarat
BAPS Pramukh Swami Hospital, Surat, Gujarat
Medanta - The Medicity Multi-Speciality Hospital, Gurugram, Gurugram, Haryana
Kasturba Medical College Hospitals (KMC Hospitals), Mangalore, Mangalore, Karnataka
Gleneagles Hospital, Super-speciality and Transplant Centre, Parel, Mumbai, Maharashtra
Seth GS medical college and KEM Hospital, Mumbai, Maharashtra
Midas Multispeciality Hospital, Nagpur, Maharashtra
Institute of liver and Biliary Sciences, Ghitorni, New Delhi
All India Institute of medical Sciences, New Dehli, New Delhi
Fortis Heart Institute and Multispeciality Hospital, Chandigarh,, Punjab
Post Graduate Institute of Medical Education & Research_Chandigarh, Chandigarh, Punjab
S.R.Kalla Memorial Gastro & General Hospital, Jaipur, Rajasthan
Osmania General Hospital, Hyderabad, Telagana
Dr P V Rao - Diabetes Research Centre, Hyderabad, Telangana
Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona, Ancona, Not set
Azienda Socio Sanitaria Territoriale (ASST) Papa Giovanni XXIII, Bergamo, Not set
Azieda Ospedaliero-Universitaria, Policlinico S. Orsola-Malp, Bologna, Not set
AOU Careggi Padiglione 16 San Luca, 3° piano, Firenze, Not set
Azienda Ospedaliera di Padova Clin.Med.3, Padova, Not set
AOU Pisana Stabilimento di Cisanello EDIFICIO 6, Piano 5, Pisa, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Not set
Policlinico Università Campus Biomedico di Roma, Rome, Not set
Chiba University Hospital_Chiba-shi, Chiba, Chiba-shi, Chiba, Not set
Fukui-ken Saiseikai Hospital, Internal Medicine, Fukui-shi, Fukui, Not set
Hamamatsu University Hospital, Hamamatsu-shi, Shizuoka, Not set
JA Hiroshima General Hospital, Hatsukaichi-shi, Hiroshima, Not set
University Hospital Kyoto Prefectual University of Medicine, Kamigyo-ku, Kyoto, Not set
St. Marianna University School of Medicine Hospital, Kawasaki-shi, Kanagawa, Not set
Kumamoto Shinto General Hospital, Kumamoto-shi, Kumamoto, Not set
Toranomon Hospital, Hepatology, Minato-ku, Tokyo, Not set
Kawasaki Medical School General Medical Center, Okayama-shi, Okayama, Not set
Saga University Hospital_Liver Center, Saga-shi, Saga, Not set
Sendai Kousei Hospital, Sendai-shi, Miyagi, Not set
Saiseikai Suita Hospital, Gastroenterology, Suita-shi, Osaka, Not set
Ehime University Hospital, Toon-shi, Ehime, Not set
Saiseikai Wakayama Hospital, Wakayama-shi, Wakayama, Not set
Yokohama City University Hospital, Gastrointestinal Medicine, Yokohama-shi, Kanagawa, Not set
Korea University Ansan Hospital, Ansan, Gyeonggi-do
Kyungpook National University Hospital, Daegu, Not set
Yeungnam Univ. Medical Center, Daegu, Not set
Keimyung University Dongsan Hospital, Daegu, Not set
Wonju Severance Christian Hospital, Gangwon-do, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
SMG-SNU Boramae Medical Center, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
Hospital Universiti Sains Malaysia, Kota Bharu, Kelantan
University Malaya Medical Centre, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur
Hospital Selayang, Batu Caves, Not set
ID Clinic Arkadiusz Pisula, Mysłowice, Malopolskie
Spolka Lekarzy Intercor Sp. z o.o., Bydgoszcz, Not set
Clinical Medical Research Korfantego - Ambulatoryjna Opieka, Katowice, Not set
Uniwersyteckie Centrum Kliniczne im. Prof. K. Gibińskiego Śl, Katowice, Not set
Krakowskie Centrum Medyczne Sp. z o.o., Krakow, Not set
"LANDA" Katarzyna Agata Landa, Kraków, Not set
EMC Instytut Medyczny S.A., Wroclaw, Not set
Centrum Badan Klinicznych, Wroclaw, Not set
FutureMeds Sp. z o.o., Wroclaw, Not set
Unidade Local De Saude De Matosinhos E.P.E., Senhora Da Hora, Matosinhos, Matosinhos
Unidade Local De Saude De Santa Maria E.P.E., Lisboa, Not set
FDI Clinical Research, San Juan, Not set
Penza Regional Clinical Hospital named after N.N. Burdenko, Penza, Not set
National University Hospital Singapore_Tahir Building, Singapore, Not set
National University Hospital_TBD, Singapore, Not set
Singapore General Hospital, Singapore, Not set
Changi General Hospital, Singapore, Not set
Complejo Hospitalario de Pontevedra - Hospital de Montecelo, Pontevedra, Galicia
Hospital Vall d'Hebron, Barcelona, Not set
Hospital Universitario Marqués de Valdecilla, Santander, Not set
Hospital Virgen del Rocío, Sevilla, Not set
Hospital Clínico de Valladolid, Valladolid, Not set
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set
National Cheng Kung University Hospital, Tainan, Not set
National Taiwan University Hospital, Taipei, Not set
T.C. Saglık Bakanlıgı Adana Sehir Egitim ve Arastirma Hastan, Adana, Not set
Hacettepe Universitesi Tıp Fakültesi- Gastroenteroloji, Ankara, Not set
Gazi University Medical Faculty, Ankara, Not set
Bezmialem Vakif Universitesi Tip Fakultesi Hastanesi-Gastroe, Istanbul, Not set
Marmara Univ. Pendik Gastroenterology, Istanbul, Not set
Kocaeli Universitesi Tıp Fakültesi Gastroenteroloji ve Hepat, Kocaeli, Not set
Royal Devon & Exeter NHS Foundation Trust, Exeter, Not set
Conditions: Non-alcoholic Steatohepatitis
Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease
Active Not Recruiting
The study will look at the effects of NNC0194-0499, cagrilintide and semaglutide, on liver damage and alcohol use in participants with alcoholic liver disease. Participants will get NNC0194-0499, semaglutide, cagrilintide or ''dummy" medicine in different treatment combinations. Which treatment participants get is decided by chance. The study will last for about 39 weeks.
The study will look at the effects of NNC0194-0499, cagrilintide and semaglutide, on liver damage and alcohol use in participants with alcoholic liver disease. Participants will get NNC0194-0499, semaglutide, cagrilintide or ''dummy" medicine in different treatment combinations. Which treatment participants get is decided by chance. The study will last for about 39 weeks. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2025
Locations: The Institute for Liver Health, Chandler, Arizona +85 locations
The Institute for Liver Health, Chandler, Arizona
Arizona Liver Center, Tucson, Arizona
Del Sol Research Management, LLC, Tucson, Arizona
OM Research LLC, Lancaster, California
California Liver Research Institute, Pasadena, California
Covenant Metabolic Specialists LLC, Fort Myers, Florida
Miguel Rebollar PA, Hialeah, Florida
UF Hlth Jacksonville, Jacksonville, Florida
Univ of Miami/Schiff Ctr, Miami, Florida
Covenant Metabolic Specialists LLC, University Park, Florida
Rush University Med. Cntr, Chicago, Illinois
Kansas Medical Clinic, PA, Topeka, Kansas
Boston Medical Center_Cary, Boston, Massachusetts
Mayo Clinic Rochester, Rochester, Minnesota
Jubilee Clinical Research, Inc., Las Vegas, Nevada
DSI Research,LLC, Springboro, Ohio
University of Pennsylvania Hospital, Philadelphia, Pennsylvania
Digestive Health Research, TN, Hermitage, Tennessee
Texas Clinical Research Institute, Arlington, Texas
The Liver Institute, Dallas, Texas
South Texas Research Institute, Edinburg, Texas
Baylor St. Luke's Medical Center, Houston, Texas
Houston Research Institute, Houston, Texas
Amer. Rrsch Corp-TX Liver Inst, San Antonio, Texas
Pinnacle Clinical Research, San Antonio, Texas
Velocity Clinical Res, Waco, Waco, Texas
Momentum Clinical Research Darlinghurst, Darlinghurst, New South Wales
Westmead Hospital, Westmead, New South Wales
Eastern Clinical Research Unit Box Hill, Box Hill, Victoria
St Vincent's Hospital (Melbourne), Fitzroy, Victoria
Austin Health, Heidelberg, Victoria
Fiona Stanley Hospital - Hepatology, Murdoch, Western Australia
Multiprofile Hospital For Active Treatment St. Ivan Rilski Gorna Oriahovitsa EOOD, Gorna Oryahovitsa, Not set
"Acibadem City Clinic UMHAT Tokuda", Sofia, Not set
UMHAT "Sv. Ivan Rilski", Clinic of Gastroenterology, Sofia, Not set
"DCC XX - Sofia" EOOD, Sofia, Not set
Medical Center Synexus Sofia, Sofia, Not set
University of Calgary Liver Unit-(HMRC), Calgary, Alberta
GI Research Inst Foundation, Vancouver, British Columbia
London Health Sciences Centre- University Hospital, London, Ontario
TDDA Specialty Research, Vaughan, Ontario
Ctr de Med Metab de Lanaudiere, Terrebonne, Quebec
Krajská nemocice Liberec, a.s, Liberec, Not set
Vseobecna Fakultni nemocnice v Praze, Prague 2, Not set
Aalborg Universitetshospital, Aalborg, Not set
Herlev Hospital, Herlev, Not set
Hvidovre Hospital - Gastroenheden, Hvidovre, Not set
Odense University Hospital, Odense C, Not set
Centre Hospitalier Universitaire D'Angers-1, Angers, Not set
Centre Hospitalier Universitaire de Lille-Hopital Claude Huriez, Lille, Not set
Centre de Recherche Clinique Portes Du Sud, Venissieux, Not set
Universitätsklinikum des Saarlandes - Klinik für Innere Medizin II, Homburg, Not set
Universitätsklinikum Leipzig - Klinik und Poliklinik für Onkologie, Gastroenterologie, Hepatologie und Pneumologie, Leipzig, Not set
Universitätsmedizin der Johannes-Gutenberg-Universität Mainz - Hepatologie, Mainz, Not set
Universitätsklinikum Würzburg, Zentrum für Innere Medizin (ZIM), Würzburg, Not set
University Hospital of Athens ATTIKON, Athens, Attica
"Laiko" General Hospital of Athens, Goudi/Athens, Not set
'Ippokrateio' General Hospital of Thessaloniki, Thessaloniki, Not set
AOU Careggi Firenze, Firenze, Toscana
IRCCS Azienda Ospedaliero Universitaria San Martino - IST, Genova, Not set
Ospedale Evangelico Betania, Naples, Not set
Azienda Ospedaliera di Padova, Padova, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Not set
Juntendo University Hospital, Gastroenterology, Bunkyo-ku, Tokyo, Not set
Akaicho Clinic, Chiba-shi, Chiba, Not set
Ogaki Municipal Hospital_Gastroenterology and Hepatology, Gifu, Not set
Naka Kinen Clinic, Ibaraki, Not set
Ishikawa Prefectural Central Hospital_Gastroenterology, Kanazawa-shi, Ishikawa, Not set
Kumamoto Shinto General Hospital, Kumamoto-shi, Kumamoto, Not set
Toranomon Hospital, Hepatology, Minato-ku, Tokyo, Not set
Heartlife Hospital, Nakagamigun, Okinawa, Not set
Oita Cardiovascular Hospital, Oita-shi, Oita, Not set
Japan Community Health care Organization Hokkaido Hospital, Sapporo-shi, Hokkaido, Not set
Saiseikai Suita Hospital, Gastroenterology, Suita-shi, Osaka, Not set
Nihon University Itabashi Hospital, Tokyo, Not set
Erasmus MC, Rotterdam, Not set
Centrum Medyczne Intercor Sp. z o.o., Bydgoszcz, Kujawsko-Pomorskie
Gastromed Sp. z o.o., Toruń, Kujawsko-pomorskie
ID Clinic Arkadiusz Pisula, Mysłowice, Malopolskie
PANSTWOWY INSTYTUT MEDYCZNY MSWiA, Warszawa, Mazowieckie
Sonomed Sp. Z O.O., Szczecin, Zachodniopomorskie
Hospital Universitario Marqués de Valdecilla, Santander, Cantabria
Hospital Clinic i Provincial, Barcelona, Cataluña
Hospital Clínico Universitario de Valladolid, Valladolid, España
Complejo Hospitalario de Pontevedra - Hospital de Montecelo, Pontevedra, Galicia
Hospital Vall d'Hebron, Barcelona, Not set
Conditions: Alcohol-related Liver Disease
Research Study Looking at How Well Semaglutide Works in People Living With Obesity and Prediabetes
Completed
This study looks at how well a new medicine, called semaglutide, works at helping people with obesity and prediabetes.
This study will look at how much weight participants lose, and if participants can go from having blood sugar that is higher than normal (prediabetes) to having normal blood sugar.
Semaglutide is compared to a "dummy" medicine. The "dummy" medicine looks like semaglutide but has no effect on the body.
In addition to taking the medicine, participants will have talks with study... Read More
This study looks at how well a new medicine, called semaglutide, works at helping people with obesity and prediabetes.
This study will look at how much weight participants lose, and if participants can go from having blood sugar that is higher than normal (prediabetes) to having normal blood sugar.
Semaglutide is compared to a "dummy" medicine. The "dummy" medicine looks like semaglutide but has no effect on the body.
In addition to taking the medicine, participants will have talks with study staff about healthy food choices, how to be more physically active and what participants can do to lose weight.
Participants will either get semaglutide or "dummy" medicine - which treatment they get is decided by chance. Participants are 2 times as likely to get semaglutide as "dummy" medicine.
Participants will need to take 1 injection once a week. The study medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm.
The study will last for about 19 months. Participants have to take the study medicine every week for the first 12 months. The last 7 months participants will not take any medication.
Participants will have 14 clinic visits and 1 phone call with the study staff. At 9 of the clinic visits Participants will have blood samples taken. Women cannot take part if pregnant, breast-feeding or plan to become pregnant during the study period. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/12/2025
Locations: University of Calgary, Calgary, Alberta +29 locations
University of Calgary, Calgary, Alberta
C-endo Diab Endo Clin Calgery, Calgary, Alberta
Ocean West Research Clinic, Surrey, British Columbia
G.A. Research Associates Ltd., Moncton, New Brunswick
LMC ClinRsrh Inc.Brampton, Brampton, Ontario
LMC Clin Res Inc. Thornhill, Concord, Ontario
Wharton Med Clin Trials, Hamilton, Ontario
Premier Clinical Trial Research Network (PCTRN), Hamilton, Ontario
Milestone Research, London, Ontario
Toronto Sleep Institute/MedSleep, Toronto, Ontario
Diabetes Heart Research Centre, Toronto, Ontario
Centre Medical Acadie, Montreal, Quebec
LMC Clin Rsrch Inc. (Montreal), Saint-Laurent, Quebec
Centre de recherché du CHUS, Sherbrooke, Quebec
Ctr de Med Metab de Lanaudiere, Terrebonne, Quebec
Aarhus Universitetshospital Diabetes og Hormonsygdomme, Aarhus N, Not set
Hvidovre Hospital Endokrinologisk forsknings afsnit 159, Hvidovre, Not set
Obesity Research Unit, Helsinki, Not set
StudyCor, Jyväskylä, Not set
Hospital Gregorio Marañón, Madrid, Not set
Hospital Clinico San Carlos, Madrid, Not set
Hospital Infanta Luisa, Sevilla, Not set
Clifton Medical Centre, Rotherham, South Yorkshire
The Health Centre, Bradford-on-Avon, Not set
WISDEM Centre, Coventry, Not set
Claremont Medical Practice, Exmouth, Not set
GP Direct, Harrow, Not set
Guys Hospital, London, Not set
The Staploe Medical Centre, Soham, Not set
MyHealth - Strensall Health Care Centre, Strensall, Not set
Conditions: Obesity
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