All Clinical Trials in Canada

A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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The Development, Safety, and Feasibility of an Artificial Intelligence-Powered Platform (NodeAI) for Real-Time Prediction of Mediastinal Lymph Node Malignancy During Endobronchial Ultrasound Staging for Lung Cancer

NCT06540196

Recruiting

Lung cancer is the leading cause of annual cancer deaths globally, more than breast, prostate, and colon cancers combined. The staging of chest lymph nodes (LNs) is a crucial step in the lung cancer diagnostic pathway because it aids in treatment decisions - whether a patient is a candidate for lung resection, chemotherapy, radiation, or multimodal treatments. Endobronchial Ultrasound Transbronchial Needle Aspiration (EBUS-TBNA) is the current standard for chest nodal staging for non-small cell lung cancer (NSCLC), and guidelines mandate that Systematic Sampling (SS) of at least 3 chest LN stations be routinely performed for accurate staging. Unfortunately, EBUS-TBNA yields inaccurate results in 40% of patients, leading to misinformed treatment decisions. This proportion is much higher in patients with Triple Normal LNs \[LNs that appear normal on computed tomography (CT) scans, positron emission tomography (PET) scans, and EBUS\], which have been found to have a \> 93% chance of being truly benign. This is because EBUS-TBNA is based on ultrasound, whose success highly depends on the skill of the person performing it (operator). When the operator makes an error, the entire procedure is jeopardized. This causes downstream delays in treatment due to repeated testing and ill-informed treatment decisions. Over the past decade, the investigator has been conducting a series of research studies and trials: the development and validation of the Canada Lymph Node Score (CLNS) - a surgeon-derived semi-quantitative measure of LN malignancy; an Artificial Intelligence (AI)-based version of the CLNS to predict malignancy; and a fully autonomous AI that learned to predict malignancy directly from ultrasound images, to introduce AI to the decision-making pathway in NSCLC. This resulted in the creation of an AI-powered software to predict malignancy in mediastinal LNs of patients with lung cancer. The software is currently housed in cloud storage and its applications are latent - which means that LN images must be uploaded to the software, and results are received at a future time. In its current form, the software is not ready for clinical application due to this latency. In this project, the investigator aims to build a point-of-care device which will house the software (NodeAI) and deliver real-time results to the surgeon, and this device will be tested in a clinical trial. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/11/2025

Locations: St. Joseph's Healthcare Hamilton / McMaster University, Hamilton, Ontario

Conditions: Lung Cancer, Non Small Cell Lung Cancer

Learn More ›

A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor

NCT04008797

Recruiting

The primary objective of this study is to assess the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of E7386 in combination with other anticancer drug(s), and to determine the optimal dose of E7386 in combination with lenvatinib in endometrial carcinoma (EC) (for EC Dose Optimization Part only).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/11/2025

Locations: UAMS, Little Rock, Arkansas +107 locations

UAMS, Little Rock, Arkansas

University of California San Diego (UCSD) - Moores Cancer Center(All), La Jolla, California

Cedars-Sinai Medical Center, Los Angeles, California

Pasadena Liver Center, Pasadena, California

California Pacific Medical Center, San Francisco, California

UCLA University of California - Los Angeles, Santa Monica, California

John Muir Clinical Research, Walnut Creek, California

University of Colorado Cancer Center - Anschutz Medical Campus, Aurora, Colorado

Uni. Of Miami- Sylvester Cancer Centre, Miami, Florida

Florida Cancer Specialists - South, Sarasota, Florida

Florida Cancer Specialists - East, West Palm Beach, Florida

Women's Cancer Care - Covington, LA, Covington, Louisiana

University Of Mississippi Medical Center, Jackson, Mississippi

Kansas City Research Institute, Kansas City, Missouri

Montefiore Medical Center (MMC) - Jack D. Weiler Hospital, Bronx, New York

Perlmutter Cancer Center- NYU Langone Health, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

MetroHealth Medical Center, Cleveland, Ohio

ProMedica Flower Hospital, Sylvania, Ohio

University of Oklahoma Health Science Center, Oklahoma City, Oklahoma

Medical University of South Carolina, Charleston, South Carolina

Sanford Cancer Centre, Sioux Falls, South Dakota

Tennessee Oncology, Nashville, Tennessee

Vanderbilt University Medical Center (VUMC) - Vanderbilt-Ingram Cancer Center (VICC) - Nashville, Nashville, Tennessee

Mary Crowley Cancer Research, Dallas, Texas

University of Texas Southwestern Medical, Dallas, Texas

MD Anderson Cancer Center, Houston, Texas

Fred Hutchinson/University of Washington Cancer Consortium, Seattle, Washington

Sunnybrook Hospital, Toronto, Ontario

CHUM, Unit for Innovative Therapies, Montreal, Quebec

McGill University Health Centre, Montreal, Quebec

Beijing Cancer Hospital, Beijing, Not set

Peking Union Medical College Hospital, Beijing, Not set

Bethune Hospital of Jilin University, Changchun, Not set

Fujian Provincial Cancer Hospital, Fuzhou, Not set

Sun Yan-sen University Cancer Center, Guangzhou, Not set

Sun Yat-Sen Memrial Hospital, Sun Yat-Sen University, Guangzhou, Not set

Cancer Hospital of Shandong First Medical University, Jinan, Not set

Yunnan Cancer Hospital, Kunming, Not set

Fudan University Cancer Center, Shanghai, Not set

The Tenth People's Hospital; Shanghai Tongji University, Shanghai, Not set

Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, Shenzhen, Not set

Tianjin Cancer Hospital, Tianjin, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Odense University Hospital, Odense, Not set

CHU Amiens-Picardie (Hopital Sud), Amiens, Not set

CHU Bordeaux, Bordeaux, Not set

CHU Cavale Blanche, Brest, Not set

Centre François Baclesse, Caen, Not set

Centre Jean Perrin, Clermont-Ferrand, Not set

Hôpital Beaujon, Clichy, Not set

Centre Georges-François Leclerc, Dijon, Not set

Grenoble University Hospital (Centre Hospitalier Universitaire Grenoble Alpes), La Tronche, Not set

CHU de LILLE - Hôpital HURIEZ, Lille, Not set

Hepatology, Hopital de la Croix-Rousse - 103 grande rue de la Croix-Rousse, Lyon, Not set

Centre Léon Bérard, Lyon, Not set

Institut Paoli-Calmettes, Marseille, Not set

Centre Antoine Lacassagne, Nice, Not set

Institut Curie - Centre de Recherche, Paris, Not set

APHP Hospital Saint-Antoine, Paris, Not set

AP-HP Université de Paris, Port Royal, Paris, Not set

Hopital Europeen Georges-Pompidou (HEGP), Paris, Not set

Hopital de la Croix Saint-Simon, Paris, Not set

Centre Hospitalier Universitaire de Bordeaux (CHU Bordeaux)(Hopitaux de Bordeaux) - Groupe hospitalier Sud - Hopital Haut-Levequ, Pessac, Not set

Centre Hospitalier Universitaire (CHU) de Poitiers, Poitiers, Not set

Insitute de Cancérologie de l'Ouest - Centre René Gauducheau, Saint-Herblain, Not set

ICANs, Strasbourg, Not set

Gustave Roussy Institute (IGR), Villejuif, Not set

Clinica Oncologica AOU (Azienda Ospedaliero Universitaria) delle Marche, Ancona, Not set

Istituto Clinico Humanitas, Rozzano, Milan, Not set

Fondazione Policlinico Gemelli IRCCS, Rome, Not set

Eisai Trial Site #5, Nagoya, Aichi

Eisai Trial Site #11, Toyoake, Aichi

Eisai Trial Site #2, Kashiwa, Chiba

Eisai Trial Site #8, Matsuyama, Ehime

Eisai Trial Site #7, Kurume, Fukuoka

Eisai site #13, Akashi, Hyogo

Eisai Trial Site #10, Kawasaki, Kanagawa

Eisai Trial Site #12, Kamigyo-ku, Kyoto

Eisai Trial Site #3, Osakasayama, Osaka

Eisai Trial Site #9, Hidaka, Saitama

Eisai Trial Site #1, Chuo-Ku, Tokyo

Eisai Trial Site #6, Koto-ku, Tokyo

Eisai Site 15, Minato-ku, Tokyo

Eisai Trial Site #4, Chiba, Not set

Eisai site #14, Niigata, Not set

Eisai Trial Site #1, Seongnamsi Bundang, Gyeonggi-Do

National Cancer Center, Goyang-si Gyeonggi-do, Ilsandong-gu

Korea University Guro Hospital, Guro-gu, Seoul

Eisai Trial Site #5, Jongno-gu, Seoul

Seoul National University Hospital, Jongno-gu, Seoul

Seoul St. Mary's Hospital, Seocho-Gu, Seoul

Eisai Trial Site #2, Seodaemun, Seoul

Asan Medical Centre, Songpa-Gu, Seoul

Eisai Trial Site #4, Songpa-gu, Seoul

Eisai Trial Site #3, Seoul, Not set

H. Clinico San Carlos, San Carlos, Madrid

Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron (VHIO), Barcelona, Not set

University Hospital A Coruña, Coruna, Not set

Hospital Universitario de Jaén, Jaen, Not set

Clínica Universidad de Navarra, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Chang Gung Medical Foundation - Kaohsiung Branch, Kao-Hsiung, Not set

Taichung Veterans General Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Chang Gung Medical Foundation - Linkou Branch, Taoyuan, Not set

Conditions: Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

Learn More ›

Optimizing Tracheal Intubation Outcomes and Neonatal Safety

NCT05838690

Recruiting

The purpose of the study is to assess the impact of a personalized intubation planning tool, the Personalized INtubation Safety (PINS) Bundle on intubation procedural safety and clinical outcomes among patients intubated in the neonatal intensive care unit (NICU) setting.

Gender:

ALL

Ages:

1 year and below

Trial Updated:

06/10/2025

Locations: University of Arkansas Medical Sciences, Little Rock, Arkansas +7 locations

Conditions: Infant, Intubation Complication

Learn More ›

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

NCT03550391

Recruiting

Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to small spots in the brain while excluding the surrounding normal brain. Whole brain radiation therapy with hippocampal avoidance (HA-WBRT) is when radiation therapy is given to the whole brain, while trying to decrease the amount of radiation that is delivered to the area of the hippocampus. The hipp... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/10/2025

Locations: University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona +85 locations

University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona

University of Arizona Cancer Center-North Campus, Tucson, Arizona

City of Hope Corona, Corona, California

City of Hope Comprehensive Cancer Center, Duarte, California

City of Hope at Irvine Lennar, Irvine, California

UC San Diego Moores Cancer Center, La Jolla, California

City of Hope Antelope Valley, Lancaster, California

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California

Kaiser Permanente-Rancho Cordova Cancer Center, Rancho Cordova, California

Rohnert Park Cancer Center, Rohnert Park, California

The Permanente Medical Group-Roseville Radiation Oncology, Roseville, California

South Sacramento Cancer Center, Sacramento, California

Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California

City of Hope South Pasadena, South Pasadena, California

Kaiser Permanente Cancer Treatment Center, South San Francisco, California

City of Hope South Bay, Torrance, California

City of Hope Upland, Upland, California

Boca Raton Regional Hospital, Boca Raton, Florida

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Mayo Clinic in Florida, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Memorial Hospital West, Pembroke Pines, Florida

UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida

Moffitt Cancer Center, Tampa, Florida

Piedmont Hospital, Atlanta, Georgia

Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia

Emory Saint Joseph's Hospital, Atlanta, Georgia

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Northwestern University, Chicago, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Loyola University Medical Center, Maywood, Illinois

HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois

Methodist Medical Center of Illinois, Peoria, Illinois

OSF Saint Francis Medical Center, Peoria, Illinois

Carle Cancer Center, Urbana, Illinois

Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois

Community Cancer Center North, Indianapolis, Indiana

Iowa Methodist Medical Center, Des Moines, Iowa

Luminis Health Anne Arundel Medical Center, Annapolis, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Tufts Medical Center, Boston, Massachusetts

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Mayo Clinic in Rochester, Rochester, Minnesota

Regions Hospital, Saint Paul, Minnesota

Saint Francis Medical Center, Cape Girardeau, Missouri

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Siteman Cancer Center-South County, Saint Louis, Missouri

Missouri Baptist Medical Center, Saint Louis, Missouri

Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri

Billings Clinic Cancer Center, Billings, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

AtlantiCare Surgery Center, Egg Harbor Township, New Jersey

State University of New York Upstate Medical University, Syracuse, New York

SUNY Upstate Medical Center-Community Campus, Syracuse, New York

Mission Hospital, Asheville, North Carolina

Cone Health Cancer Center, Greensboro, North Carolina

East Carolina University, Greenville, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Bismarck Medical Center, Bismarck, North Dakota

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon

Geisinger Medical Center, Danville, Pennsylvania

Fox Chase Cancer Center Buckingham, Furlong, Pennsylvania

Fox Chase Cancer Center, Philadelphia, Pennsylvania

Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania

Self Regional Healthcare, Greenwood, South Carolina

Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah

Dartmouth Cancer Center - North, Saint Johnsbury, Vermont

Medical College of Wisconsin, Milwaukee, Wisconsin

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta

Cross Cancer Institute, Edmonton, Alberta

BCCA-Vancouver Cancer Centre, Vancouver, British Columbia

QEII Health Sciences Centre/Nova Scotia Health Authority, Halifax, Nova Scotia

Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario

London Regional Cancer Program, London, Ontario

University Health Network-Princess Margaret Hospital, Toronto, Ontario

CSSS Champlain-Charles Le Moyne, Greenfield Park, Quebec

CHUM - Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec

The Research Institute of the McGill University Health Centre (MUHC), Montreal, Quebec

Jewish General Hospital, Montreal, Quebec

CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ), Quebec City, Quebec

Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec

Conditions: Brain Metastases

Learn More ›

Study of GS-4528 in Adults With Solid Tumors

NCT05840224

Recruiting

The goals of this clinical study are to identify if GS-4528 alone or in combination with anti-programmed cell death protein 1 (PD-1) (Anti-PD-1) Monoclonal Antibody is safe and tolerable in people with solid tumors and to identify the recommended dose of GS-4528 for further development that is safe to give to people alone or in combination with Anti-PD-1 Monoclonal Antibody. The primary objectives of this study are: * To assess the safety and tolerability of GS-4528 as monotherapy and in combi... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/10/2025

Locations: The University of Washington/FHCC, Seattle, Washington +15 locations

Conditions: Solid Tumor

Learn More ›

Vancomycin Dosing for Serious MRSA Infections: A Non-inferiority Randomized Trial of Trough Level Versus AUC/MIC

NCT04793152

Recruiting

Intravenous vancomycin is considered first line therapy for serious methicillin-resistant Staphylococcus aureus (MRSA) infections including bacteremia, central nervous system infection, pneumonia, pleural space infection, bone or joint infection, prosthetic joint infection and deep abscesses. The effectiveness and toxicity of vancomycin depend on its dosing and chosen target. The most recent guidelines suggest targeting area under the curve over 24 hours over minimum inhibitory concentration (AU... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/10/2025

Locations: Hamilton Health Sciences, Hamilton, Ontario +3 locations

Conditions: MRSA

Learn More ›

Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Perioperative AF After Noncardiac Surgery

NCT03968393

Recruiting

Multinational, investigator-initiated study of oral anticoagulation versus no anticoagulation for the prevention of stroke and other adverse cardiovascular events in patients with transient perioperative atrial fibrillation after noncardiac surgery and additional stroke risk factors.

Gender:

ALL

Ages:

55 years and above

Trial Updated:

06/10/2025

Locations: Cedars-Sinai Medical Center, Los Angeles, California +104 locations

Cedars-Sinai Medical Center, Los Angeles, California

Mcgovern Medical School at University of Texas, Houston, Texas

Clinica Coronel Suarez, Coronel Suárez, Buenos Aires

Instituto de Investigaciones Clinicas Rosario, Rosario, Santa Fe

Instituto Cardiovascular de Rosario, Rosario, Santa Fe

Centro Integral de Arritmias de Tucuman (CIAT), San Miguel De Tucumán, Tucuman

Hospital Municipal Chivilcoy, Chivilcoy, Not set

Hospital Privado de Rosario, Santa Fe, Not set

Sanatorio Cisma, Tucuman, Not set

Canberra Hospital, Garran, Australian Capital Territory

Bankstown Hospital, Bankstown, New South Wales

Royal Prince Alfred Hospital, Camperdown, New South Wales

Concord Repatriation General Hospital, Concord, New South Wales

Liverpool Hospital, Liverpool, New South Wales

John Hunter Hospital, Newcastle, New South Wales

Westmead Hospital, Westmead, New South Wales

Sunshine Coast Hospital and Health Service, Birtinya, Queensland

Royal Brisbane and Women's Hospital, Herston, Queensland

Redcliffe Hospital, Redcliffe, Queensland

Royal Adelaide Hospital, Adelaide, South Australia

Box Hill Hospital, Box Hill, Victoria

Northeast Health Wangaratta, Wangaratta, Victoria

Royal Perth Hospital, Perth, Western Australia

Instituto do Coração do Hospital das Clínicas da FMUSP, Cerqueira César, Not set

Hospital de Clinicas de Porto Alegre, Porto Alegre, Not set

Foothills Hospital, Calgary, Alberta

University of Alberta Hospital, Edmonton, Alberta

Medicine Hat Regional Hospital, Medicine Hat, Alberta

East Kootenay Regional Hospital, Cranbrook, British Columbia

Fraser Health Authority, Surrey, British Columbia

Vancouver General Hospital, Vancouver, British Columbia

Health Sciences Centre Winnipeg, Winnipeg, Manitoba

Dr.-Georges-L.-Dumont University Hospital Centre, Moncton, New Brunswick

Halifax Infirmary, Halifax, Nova Scotia

Cape Breton University, Sydney, Nova Scotia

Cambridge Cardiac Care Centre, Cambridge, Ontario

Hamilton General Hospital, Hamilton, Ontario

St. Joseph's Healthcare Hamilton, Hamilton, Ontario

Juravinski Hospital, Hamilton, Ontario

Kingston General Hospital, Kingston, Ontario

London Health Sciences Centre - University Hospital, London, Ontario

The Ottawa Hospital General Campus, Ottawa, Ontario

Niagara Health System - St. Catharine's Site, St. Catharines, Ontario

Cortelluci Vaughan Hospital, Vaughan, Ontario

Centre Hospitalier de l'Université de Montréal, Montréal, Quebec

CHU de Quebec Universite Laval, Québec, Quebec

Hôpital Fleurimont du Centre hospitalier universitaire de Sherbrooke, Sherbrooke, Quebec

Regina General Hospital, Regina, Saskatchewan

Royal University Hospital, Saskatoon, Saskatchewan

Aarhus University Hospital, Aarhus, Not set

Hospital South West Jutland - University Hospital of Southern Denmark, Esbjerg, Not set

Odense University Hospital, Odense, Not set

Southwest Finland Wellbeing County (VARHA), Turku, Not set

Universitatsklinikum Leipzig, Leipzig, Not set

GNRC Medical, North Guwāhāti, Assam

Marengo CIMS Hospital, Ahmedabad, Gujarat

NU Hospitals, Bangalore, Karnataka

Govt. T.D. Medical College, Alappuzha, Kerala

Amala Institute of Medical Sciences, Thrissur, Kerala

Amala Institute, Thrissur, Kerala

St. John's Medical College Hospital, Bangalore, Not set

JIPMER, Pondicherry, Not set

Ruby Hall Clinic, Pune, Not set

Trivandrum Medical, Thiruvananthapuram, Not set

ASST Grande Ospedale Metropolitano Niguarda, Milano, Milan

Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Not set

Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, Milan, Not set

La Maddalena, Palermo, Not set

Piacenza Ospedale, Piacenza, Not set

Korea Univesrity Anam Hospital, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Seoul National University Bundang Hospital, Seoul, Not set

Nobel Medical College Teaching Hospital, Biratnagar, Not set

B.P. Koirala Institute of Health Sciences, Koshi, Not set

B and B Hospital, Lalitpur, Not set

Jeroen Bosch Hospital, 's-Hertogenbosch, Not set

Noordwest Ziekenhuisgroep, Alkmaar, Not set

ZiekenhuisGroepTwente (ZGT), Almelo, Not set

Ziekenhuis Amstelland, Amstelveen, Not set

Rijnstate Hospital, Arnhem, Not set

Amphia Ziekenhuis Breda, Breda, Not set

Deventer Ziekenhuis, Deventer, Not set

Hospital Gelderse Vallei, Ede, Not set

Martini Hospital, Groningen, Not set

Franciscus Gasthuis, Rotterdam, Not set

Ikazia Hospital, Rotterdam, Not set

ETZ Tilburg, Tilburg, Not set

Aga Khan University, Karachi, Sindh

Maroof International Hospital, Islamabad, Not set

Shifa International Hospital, Islamabad, Not set

Dow Medical University, Karachi, Not set

Rehman Medical Institute, Peshawar, Not set

Hospital de Mar, Barcelona, Not set

Vall d'Hebron Hospital, Barcelona, Not set

Hospital de la Santa Creu i Sant Pau, Barcelona, Not set

Hospital Mutua de Terrassa, Barcelona, Not set

University Hospital Ramon y Cajal, Madrid, Not set

Hospital Universitario de Navarra, Pamplona, Not set

Karolinska Institutet Danderyd Hospital, Danderyd, Not set

Uppsala University, Uppsala, Not set

University Hospital Basel, Basel, Not set

Kantonsspital St. Gallen, St. Gallen, Not set

Kantonsspital Winterthur, Winterthur, Not set

Liverpool Heart and Chest Hospital, Liverpool, Not set

Southend Hospital, Westcliff-on-Sea, Not set

Conditions: Stroke, Atrial Fibrillation

Learn More ›

TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

NCT05848687

Recruiting

The purpose of this study is to improve upon the TINI study treatment. The study will test the ability of a type of immunotherapy called blinatumomab to clear persistent leukemia. Blinatumomab targets CD19 which is located on the leukemia cells outer membrane.

Gender:

ALL

Ages:

1 year and below

Trial Updated:

06/10/2025

Locations: Phoenix Children's Hospital, Phoenix, Arizona +24 locations

Phoenix Children's Hospital, Phoenix, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Children's Hospital Los Angeles, Los Angeles, California

Valley Children's Hospital, Madera, California

Children's Hospital of Orange County, Orange, California

Stanford University, Palo Alto, California

Rady Children's Hospital San Diego, San Diego, California

Arnold Palmer Hospital for Children, Orlando, Florida

Children's Hospital of Minnesota, Minneapolis, Minnesota

Memorial Sloan Kettering Cancer Center, New York, New York

Novant Health - Hemby Children's Hospital, Charlotte, North Carolina

Doernbecher Children's Hospital, Portland, Oregon

Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania

MD Anderson, Houston, Texas

University of Texas Health Science Center San Antonio, San Antonio, Texas

University of Utah Huntsman Cancer Institute, Salt Lake City, Utah

Children's Hospital of The King's Daughters, Norfolk, Virginia

University of Wisconsin Carbone Cancer Center, Madison, Wisconsin

Alberta Children's Hospital, Calgary, Alberta

Stollery Children's Hospital, Edmonton, Alberta

BC Children's Hospital, Vancouver, British Columbia

McMaster Children's Hospital, Hamilton, Ontario

CHU Sainte-Justine, Montréal, Quebec

Montreal Children's Hospital, Montréal, Quebec

Chu De Quebec, Quebec City, Quebec

Conditions: Lymphoblastic Leukemia

Learn More ›

Chemoradiotherapy Versus Biomarker-Guided Therapy for Elderly and Frail GBM Patients

NCT04765514

Recruiting

Currently, the optimal treatment regimen for elderly Glioblastoma (GBM) patients with poor performance status (PS) is unknown. Based on data for elderly GBM patients and the limited data for patients with poor PS, hypofractionated RT or a short course of Temozolomide (TMZ) may provide survival benefit without the added toxicity and inconvenience of a more protracted treatment regimen. In particular, treatment with RT or TMZ monotherapy on the basis of methylated O6 - methyl guanine - DNA methyltransferase (MGMT) promoter methylation status, followed by the alternative therapy at progression, may provide a safe and effective treatment regimen for patients with poor PS. The hypothesis of this trial is that in elderly GBM patients with poor performance status (age ≥ 65 years and KPS 50-70), a biomarker-guided approach to therapy results in non-inferior overall survival compared to combined TMZ/RT. Specifically, biomarker-guided therapy will consist of TMZ monotherapy for patients with a methylated MGMT promoter, and hypofractionated RT (40 Gy in 15 fractions) for patients with a non-methylated MGMT promoter. It is hypothesized that biomarker-guided therapy will result in non-inferior progression-free survival, reduced toxicity and increased cost-effectiveness compared to combined chemoradiotherapy. Primary objective: • To compare overall survival of standard vs biomarker-guided therapy in elderly and frail patients with newly diagnosed GBM. Secondary objective: * To evaluate progression-free survival following treatment in both arms. * To evaluate adverse events according to CTCAE criteria in both arms. * To evaluate health-related quality-of-life as assessed by MoCA and EORTC QLQ-C30/QLQ-BN20 questionnaires in both arms. * To evaluate cost-effectiveness of standard vs biomarker-guided therapy Methods: Patients will be randomized to two treatment groups in a 1:1 ratio. Standard Arm: TMZ with concurrent RT (combined modality arm) Patients will receive 15 days of TMZ daily with concurrent RT. TMZ will be delivered at a dose of 75 mg/m2, given daily with RT. TMZ will be administered 1 hour before each session of RT. After a 4-week break, patients will receive six cycles of adjuvant TMZ according to the standard 5-day schedule (days 1-5) every 28 days, up to 6 cycles as tolerated by the patient. The dose will be 150 mg/m2 for the first cycle and increased to 200 mg/m2 beginning with the second cycle, so long as there are no hematologic adverse events, intractable nausea or fatigue. Investigational Arm: Biomarker based treatment MGMT (+): TMZ monotherapy Patients will receive TMZ at a dose of 75 mg/m2 daily for 15 days on weekdays (Monday through Friday). This will be followed by six cycles of TMZ according to the standard 5-day schedule (days 1-5) every 28 days. The dose will be 150 mg/m2 for the first cycle and increased to 200 mg/m2 beginning with the second cycle, so long as there are no hematologic adverse events. Dose will be determined using the body surface area (BSA) calculation. MGMT methylation (-): No TMZ will be given. Participants will receive radiation treatment with 40Gy / 15 fractions over a period of 21 days (3 weeks). Upon treatment completion, participants will be followed by every 3 months for 2 years and every 6 months for years 3-5. Response and progression will be evaluated using the new international criteria proposed by the Response Assessment in Neuro-Oncology working group (RANO). Read Less

Gender:

MALE

Ages:

65 years and above

Trial Updated:

06/10/2025

Locations: Tom Baker Cancer Centre, Calgary, Alberta +1 locations

Conditions: Glioblastoma Multiforme

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Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

NCT05612347

Recruiting

This is a multi-site comparative effectiveness randomized controlled trial (RCT) comparing annual fecal immunochemical testing (FIT) and colonoscopy for post-polypectomy surveillance among adults aged 65-82 with a history of colorectal polyps who are due for surveillance colonoscopy.

Gender:

ALL

Ages:

Between 65 years and 82 years

Trial Updated:

06/10/2025

Locations: University of Alabama Birmingham, Birmingham, Alabama +15 locations

Conditions: Colorectal Polyp, Colorectal Neoplasms, Colorectal Adenoma, Colorectal Cancer, Digestive System Disease

Learn More ›

Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung Cancer

NCT04952480

Recruiting

The purpose of this study is to find out what effects of using adaptive radiotherapy to deliver chest radiation has on the ability to control lung cancer and side effects.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/10/2025

Locations: Cross Cancer Institute, Edmonton, Alberta

Conditions: Small Cell Lung Cancer

Learn More ›

Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

NCT03488693

Recruiting

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming back.

Gender:

FEMALE

Ages:

35 years and above

Trial Updated:

06/10/2025

Locations: Fairbanks Memorial Hospital, Fairbanks, Alaska +461 locations

Fairbanks Memorial Hospital, Fairbanks, Alaska

University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona

University of Arizona Cancer Center-North Campus, Tucson, Arizona

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Kaiser Permanente-Anaheim, Anaheim, California

Kaiser Permanente-Bellflower, Bellflower, California

Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California

City of Hope Corona, Corona, California

City of Hope Comprehensive Cancer Center, Duarte, California

Kaiser Permanente Dublin, Dublin, California

UC San Diego Health System - Encinitas, Encinitas, California

Fresno Cancer Center, Fresno, California

City of Hope at Irvine Lennar, Irvine, California

UC San Diego Moores Cancer Center, La Jolla, California

City of Hope Antelope Valley, Lancaster, California

Kaiser Permanente Los Angeles Medical Center, Los Angeles, California

Los Angeles General Medical Center, Los Angeles, California

USC / Norris Comprehensive Cancer Center, Los Angeles, California

Providence Queen of The Valley, Napa, California

Kaiser Permanente Oakland-Broadway, Oakland, California

Kaiser Permanente-Ontario, Ontario, California

Saint Joseph Hospital - Orange, Orange, California

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California

Desert Regional Medical Center, Palm Springs, California

Kaiser Permanente-Rancho Cordova Cancer Center, Rancho Cordova, California

Rohnert Park Cancer Center, Rohnert Park, California

The Permanente Medical Group-Roseville Radiation Oncology, Roseville, California

Mercy Cancer Center - Sacramento, Sacramento, California

Saint Helena Hospital, Saint Helena, California

Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California

Saint John's Cancer Institute, Santa Monica, California

City of Hope South Pasadena, South Pasadena, California

Kaiser Permanente Cancer Treatment Center, South San Francisco, California

City of Hope South Bay, Torrance, California

City of Hope Upland, Upland, California

Sutter Solano Medical Center/Cancer Center, Vallejo, California

BASS Medical Group - Lennon, Walnut Creek, California

UCHealth University of Colorado Hospital, Aurora, Colorado

Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado

Penrose-Saint Francis Healthcare, Colorado Springs, Colorado

UCHealth Memorial Hospital Central, Colorado Springs, Colorado

Memorial Hospital North, Colorado Springs, Colorado

Saint Francis Cancer Center, Colorado Springs, Colorado

UCHealth - Cherry Creek, Denver, Colorado

AdventHealth Porter, Denver, Colorado

Poudre Valley Hospital, Fort Collins, Colorado

Lutheran Hospital - Cancer Centers of Colorado, Golden, Colorado

Banner North Colorado Medical Center, Greeley, Colorado

UCHealth Greeley Hospital, Greeley, Colorado

UCHealth Highlands Ranch Hospital, Highlands Ranch, Colorado

AdventHealth Littleton, Littleton, Colorado

Banner McKee Medical Center, Loveland, Colorado

Intermountain Health Lutheran Hospital, Wheat Ridge, Colorado

Smilow Cancer Hospital Care Center - Guilford, Guilford, Connecticut

Smilow Cancer Hospital-Hamden Care Center, Hamden, Connecticut

Yale University, New Haven, Connecticut

Norwalk Hospital, Norwalk, Connecticut

Smilow Cancer Hospital Care Center-Trumbull, Trumbull, Connecticut

Smilow Cancer Hospital Care Center - Waterford, Waterford, Connecticut

Helen F Graham Cancer Center, Newark, Delaware

Christiana Care Health System-Christiana Hospital, Newark, Delaware

MedStar Georgetown University Hospital, Washington, District of Columbia

MedStar Washington Hospital Center, Washington, District of Columbia

Sibley Memorial Hospital, Washington, District of Columbia

Boca Raton Regional Hospital, Boca Raton, Florida

Morton Plant Hospital, Clearwater, Florida

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida

Broward Health Medical Center, Fort Lauderdale, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Mayo Clinic in Florida, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Miami Cancer Institute, Miami, Florida

Orlando Health Cancer Institute, Orlando, Florida

Memorial Hospital West, Pembroke Pines, Florida

Miami Cancer Institute at Plantation, Plantation, Florida

Saint Anthony's Hospital Cancer Care Center, Saint Petersburg, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Moffitt Cancer Center, Tampa, Florida

Cleveland Clinic-Weston, Weston, Florida

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho

Northwestern University, Chicago, Illinois

Rush University Medical Center, Chicago, Illinois

University of Illinois, Chicago, Illinois

Swedish Covenant Hospital, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Advocate Illinois Masonic Medical Center, Chicago, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois

Crossroads Cancer Center, Effingham, Illinois

NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois

Northwestern Medicine Cancer Center Delnor, Geneva, Illinois

NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois

Ingalls Memorial Hospital, Harvey, Illinois

NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois

Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois

Loyola University Medical Center, Maywood, Illinois

UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois

University of Chicago Medicine-Orland Park, Orland Park, Illinois

Advocate Lutheran General Hospital, Park Ridge, Illinois

OSF Saint Francis Medical Center, Peoria, Illinois

UW Health Carbone Cancer Center Rockford, Rockford, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Carle Cancer Center, Urbana, Illinois

Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois

IU Health West Hospital, Avon, Indiana

IU Health North Hospital, Carmel, Indiana

UChicago Medicine Northwest Indiana, Crown Point, Indiana

IU Health Central Indiana Cancer Centers-Fishers, Fishers, Indiana

Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana

IU Health Methodist Hospital, Indianapolis, Indiana

Community Cancer Center East, Indianapolis, Indiana

Community Cancer Center South, Indianapolis, Indiana

Community Cancer Center North, Indianapolis, Indiana

IU Health Ball Memorial Hospital, Muncie, Indiana

Saint Luke's Hospital, Cedar Rapids, Iowa

Mercy Cancer Center-West Lakes, Clive, Iowa

Greater Regional Medical Center, Creston, Iowa

Iowa Methodist Medical Center, Des Moines, Iowa

Mercy Medical Center - Des Moines, Des Moines, Iowa

University of Kansas Cancer Center, Kansas City, Kansas

The University of Kansas Cancer Center - Olathe, Olathe, Kansas

University of Kansas Cancer Center-Overland Park, Overland Park, Kansas

University of Kansas Health System Saint Francis Campus, Topeka, Kansas

Ascension Via Christi Hospitals Wichita, Wichita, Kansas

Saint Elizabeth Healthcare Edgewood, Edgewood, Kentucky

Saint Elizabeth Healthcare Fort Thomas, Fort Thomas, Kentucky

Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky

Saint Joseph Hospital East, Lexington, Kentucky

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky

UofL Health Medical Center Northeast, Louisville, Kentucky

Owensboro Health Mitchell Memorial Cancer Center, Owensboro, Kentucky

LSU Health Sciences Center at Shreveport, Shreveport, Louisiana

MaineHealth Coastal Cancer Treatment Center, Bath, Maine

Lafayette Family Cancer Center-EMMC, Brewer, Maine

MaineHealth Maine Medical Center - Portland, Portland, Maine

MaineHealth Cancer Care Center of York County, Sanford, Maine

MaineHealth Maine Medical Center- Scarborough, Scarborough, Maine

Luminis Health Anne Arundel Medical Center, Annapolis, Maryland

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland

Greater Baltimore Medical Center, Baltimore, Maryland

Saint Agnes Hospital, Baltimore, Maryland

MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore, Maryland

MedStar Good Samaritan Hospital, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Suburban Hospital, Bethesda, Maryland

University of Maryland Shore Medical Center at Easton, Easton, Maryland

UM Baltimore Washington Medical Center/Tate Cancer Center, Glen Burnie, Maryland

UM Saint Joseph Medical Center, Towson, Maryland

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Lahey Hospital and Medical Center, Burlington, Massachusetts

Lowell General Hospital, Lowell, Massachusetts

Baystate Medical Center, Springfield, Massachusetts

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

McLaren Cancer Institute-Bay City, Bay City, Michigan

McLaren Cancer Institute-Clarkston, Clarkston, Michigan

Corewell Health Dearborn Hospital, Dearborn, Michigan

Corewell Health Farmington Hills Hospital, Farmington Hills, Michigan

McLaren Cancer Institute-Flint, Flint, Michigan

Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids, Michigan

Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan

West Michigan Cancer Center, Kalamazoo, Michigan

Karmanos Cancer Institute at McLaren Greater Lansing, Lansing, Michigan

McLaren Cancer Institute-Macomb, Mount Clemens, Michigan

McLaren Cancer Institute-Central Michigan, Mount Pleasant, Michigan

Trinity Health Muskegon Hospital, Muskegon, Michigan

Henry Ford Health Providence Novi Hospital, Novi, Michigan

McLaren Cancer Institute-Northern Michigan, Petoskey, Michigan

McLaren-Port Huron, Port Huron, Michigan

Corewell Health William Beaumont University Hospital, Royal Oak, Michigan

Henry Ford Health Providence Southfield Hospital, Southfield, Michigan

Munson Medical Center, Traverse City, Michigan

Corewell Health Beaumont Troy Hospital, Troy, Michigan

University of Michigan Health - West, Wyoming, Michigan

Sanford Joe Lueken Cancer Center, Bemidji, Minnesota

Miller-Dwan Hospital, Duluth, Minnesota

Abbott-Northwestern Hospital, Minneapolis, Minnesota

Hennepin County Medical Center, Minneapolis, Minnesota

Baptist Memorial Hospital and Cancer Center-Desoto, Southhaven, Mississippi

Saint Francis Medical Center, Cape Girardeau, Missouri

MU Health - University Hospital/Ellis Fischel Cancer Center, Columbia, Missouri

MU Health Care Goldschmidt Cancer Center, Jefferson City, Missouri

University of Kansas Cancer Center - North, Kansas City, Missouri

University of Kansas Cancer Center - Lee's Summit, Lee's Summit, Missouri

Missouri Baptist Medical Center, Saint Louis, Missouri

Billings Clinic Cancer Center, Billings, Montana

Saint James Community Hospital and Cancer Treatment Center, Butte, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Community Medical Center, Missoula, Montana

Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Radiation Oncology Centers of Nevada Central, Las Vegas, Nevada

Radiation Oncology Centers of Nevada Southeast, Las Vegas, Nevada

New Hampshire Oncology Hematology PA-Concord, Concord, New Hampshire

Wentworth-Douglass Hospital, Dover, New Hampshire

Exeter Hospital, Exeter, New Hampshire

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Solinsky Center for Cancer Care, Manchester, New Hampshire

Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey

Englewood Hospital and Medical Center, Englewood, New Jersey

CentraState Medical Center, Freehold, New Jersey

The Cancer Institute of New Jersey Hamilton, Hamilton, New Jersey

Memorial Sloan Kettering Monmouth, Middletown, New Jersey

Memorial Sloan Kettering Bergen, Montvale, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Sidney Kimmel Cancer Center Washington Township, Sewell, New Jersey

Robert Wood Johnson University Hospital Somerset, Somerville, New Jersey

Community Medical Center, Toms River, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Lovelace Radiation Oncology, Albuquerque, New Mexico

New Mexico Oncology Hematology Consultants, Albuquerque, New Mexico

Memorial Medical Center-Las Cruces, Las Cruces, New Mexico

Mount Sinai Queens, Astoria, New York

Montefiore Medical Center-Einstein Campus, Bronx, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

New York-Presbyterian/Brooklyn Methodist Hospital, Brooklyn, New York

Maimonides Medical Center, Brooklyn, New York

Sands Cancer Center, Canandaigua, New York

Memorial Sloan Kettering Commack, Commack, New York

Mary Imogene Bassett Hospital, Cooperstown, New York

Noyes Memorial Hospital/Myers Cancer Center, Dansville, New York

Memorial Sloan Kettering Westchester, Harrison, New York

NYU Langone Hospital - Long Island, Mineola, New York

Mount Sinai Union Square, New York, New York

Mount Sinai Chelsea, New York, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Mount Sinai West, New York, New York

Mount Sinai Hospital, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Nyack Hospital, Nyack, New York

Wilmot Cancer Institute Radiation Oncology at Greece, Rochester, New York

Highland Hospital, Rochester, New York

Rochester General Hospital, Rochester, New York

Pluta Cancer Center, Rochester, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

Memorial Sloan Kettering Nassau, Uniondale, New York

Wilmot Cancer Institute at Webster, Webster, New York

Mission Hospital, Asheville, North Carolina

Hope Women's Cancer Centers-Asheville, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Duke University Medical Center, Durham, North Carolina

CaroMont Regional Medical Center, Gastonia, North Carolina

Margaret R Pardee Memorial Hospital, Hendersonville, North Carolina

Sanford Bismarck Medical Center, Bismarck, North Dakota

Altru Cancer Center, Grand Forks, North Dakota

Cleveland Clinic Akron General, Akron, Ohio

UH Seidman Cancer Center at UH Avon Health Center, Avon, Ohio

UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio

Cleveland Clinic Mercy Hospital, Canton, Ohio

Aultman Health Foundation, Canton, Ohio

Geauga Hospital, Chardon, Ohio

Case Western Reserve University, Cleveland, Ohio

MetroHealth Medical Center, Cleveland, Ohio

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

Riverside Methodist Hospital, Columbus, Ohio

Grant Medical Center, Columbus, Ohio

The Mark H Zangmeister Center, Columbus, Ohio

Delaware Health Center-Grady Cancer Center, Delaware, Ohio

Dublin Methodist Hospital, Dublin, Ohio

Mercy Cancer Center-Elyria, Elyria, Ohio

Mount Carmel Grove City Hospital, Grove City, Ohio

OhioHealth Mansfield Hospital, Mansfield, Ohio

UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio

UH Seidman Cancer Center at Southwest General Hospital, Middleburg Heights, Ohio

University Hospitals Parma Medical Center, Parma, Ohio

Mercy Health - Perrysburg Hospital, Perrysburg, Ohio

University Hospitals Portage Medical Center, Ravenna, Ohio

UH Seidman Cancer Center at Firelands Regional Medical Center, Sandusky, Ohio

ProMedica Flower Hospital, Sylvania, Ohio

University Hospitals Sharon Health Center, Wadsworth, Ohio

Saint Ann's Hospital, Westerville, Ohio

UH Seidman Cancer Center at Saint John Medical Center, Westlake, Ohio

UHHS-Westlake Medical Center, Westlake, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Saint Charles Health System, Bend, Oregon

Good Samaritan Hospital, Corvallis, Oregon

Oregon Health and Science University, Portland, Oregon

Bryn Mawr Hospital, Bryn Mawr, Pennsylvania

Carlisle Regional Cancer Center, Carlisle, Pennsylvania

Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania

Chambersburg Hospital, Chambersburg, Pennsylvania

Ephrata Cancer Center, Ephrata, Pennsylvania

UPMC Hillman Cancer Center Erie, Erie, Pennsylvania

Saint Vincent Hospital, Erie, Pennsylvania

UPMC Cancer Center at UPMC Horizon, Farrell, Pennsylvania

Adams Cancer Center, Gettysburg, Pennsylvania

UPMC Cancer Centers - Arnold Palmer Pavilion, Greensburg, Pennsylvania

UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg, Pennsylvania

Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania

IRMC Cancer Center, Indiana, Pennsylvania

Jefferson Hospital, Jefferson Hills, Pennsylvania

UPMC-Johnstown/John P. Murtha Regional Cancer Center, Johnstown, Pennsylvania

Lancaster General Ann B Barshinger Cancer Institute, Lancaster, Pennsylvania

Lancaster General Hospital, Lancaster, Pennsylvania

UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg, Pennsylvania

Riddle Memorial Hospital, Media, Pennsylvania

Forbes Hospital, Monroeville, Pennsylvania

UPMC Cancer Center - Monroeville, Monroeville, Pennsylvania

Bryn Mawr Health Center, Newtown Square, Pennsylvania

Paoli Memorial Hospital, Paoli, Pennsylvania

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

Jefferson Torresdale Hospital, Philadelphia, Pennsylvania

Allegheny General Hospital, Pittsburgh, Pennsylvania

UPMC-Magee Womens Hospital, Pittsburgh, Pennsylvania

UPMC-Saint Margaret, Pittsburgh, Pennsylvania

West Penn Hospital, Pittsburgh, Pennsylvania

UPMC-Shadyside Hospital, Pittsburgh, Pennsylvania

UPMC-Passavant Hospital, Pittsburgh, Pennsylvania

UPMC-Saint Clair Hospital Cancer Center, Pittsburgh, Pennsylvania

Penn State Health Saint Joseph Medical Center, Reading, Pennsylvania

UPMC Washington Hospital Radiation Oncology, Washington, Pennsylvania

Reading Hospital, West Reading, Pennsylvania

Wexford Health and Wellness Pavilion, Wexford, Pennsylvania

Asplundh Cancer Pavilion, Willow Grove, Pennsylvania

Lankenau Medical Center, Wynnewood, Pennsylvania

WellSpan Health-York Cancer Center, York, Pennsylvania

UPMC Memorial, York, Pennsylvania

Women and Infants Hospital, Providence, Rhode Island

Kent Hospital, Warwick, Rhode Island

Saint Joseph's/Candler - Bluffton Campus, Bluffton, South Carolina

Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Cancer Institute - Faris, Greenville, South Carolina

Saint Francis Cancer Center, Greenville, South Carolina

Prisma Health Cancer Institute - Eastside, Greenville, South Carolina

Self Regional Healthcare, Greenwood, South Carolina

Prisma Health Cancer Institute - Greer, Greer, South Carolina

Gibbs Cancer Center-Pelham, Greer, South Carolina

The Radiation Oncology Center-Hilton Head/Bluffton, Hilton Head Island, South Carolina

Beaufort Memorial/New River Cancer Center, Okatie, South Carolina

Prisma Health Cancer Institute - Seneca, Seneca, South Carolina

Spartanburg Medical Center, Spartanburg, South Carolina

Lexington Medical Center, West Columbia, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

Baptist Memorial Hospital and Cancer Center-Memphis, Memphis, Tennessee

Houston Methodist San Jacinto Hospital, Baytown, Texas

MD Anderson in The Woodlands, Conroe, Texas

Parkland Memorial Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

University of Texas Medical Branch, Galveston, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

Ben Taub General Hospital, Houston, Texas

Houston Methodist Hospital, Houston, Texas

M D Anderson Cancer Center, Houston, Texas

Methodist Willowbrook Hospital, Houston, Texas

MD Anderson West Houston, Houston, Texas

Houston Methodist West Hospital, Houston, Texas

Doctor's Hospital of Laredo, Laredo, Texas

MD Anderson League City, League City, Texas

Houston Methodist Saint John Hospital, Nassau Bay, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

MD Anderson in Sugar Land, Sugar Land, Texas

Houston Methodist Sugar Land Hospital, Sugar Land, Texas

Houston Methodist The Woodlands Hospital, The Woodlands, Texas

American Fork Hospital / Huntsman Intermountain Cancer Center, American Fork, Utah

Sandra L Maxwell Cancer Center, Cedar City, Utah

Farmington Health Center, Farmington, Utah

Logan Regional Hospital, Logan, Utah

Intermountain Medical Center, Murray, Utah

McKay-Dee Hospital Center, Ogden, Utah

Utah Valley Regional Medical Center, Provo, Utah

Riverton Hospital, Riverton, Utah

Saint George Regional Medical Center, Saint George, Utah

University of Utah Sugarhouse Health Center, Salt Lake City, Utah

Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah

LDS Hospital, Salt Lake City, Utah

South Jordan Health Center, South Jordan, Utah

Central Vermont Medical Center/National Life Cancer Treatment, Berlin, Vermont

University of Vermont Medical Center, Burlington, Vermont

Dartmouth Cancer Center - North, Saint Johnsbury, Vermont

Augusta Health Center for Cancer and Blood Disorders, Fishersville, Virginia

Naval Medical Center - Portsmouth, Portsmouth, Virginia

CJW Medical Center - Johnston-Willis Campus, Richmond, Virginia

MultiCare Auburn Medical Center, Auburn, Washington

MultiCare Gig Harbor Medical Park, Gig Harbor, Washington

Swedish Medical Center-First Hill, Seattle, Washington

MultiCare Tacoma General Hospital, Tacoma, Washington

West Virginia University Healthcare, Morgantown, West Virginia

Langlade Hospital and Cancer Center, Antigo, Wisconsin

ThedaCare Regional Cancer Center, Appleton, Wisconsin

HSHS Sacred Heart Hospital, Eau Claire, Wisconsin

Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin

Aurora Cancer Care-Grafton, Grafton, Wisconsin

Bellin Memorial Hospital, Green Bay, Wisconsin

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin

Aurora BayCare Medical Center, Green Bay, Wisconsin

University of Wisconsin Carbone Cancer Center - Johnson Creek, Johnson Creek, Wisconsin

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin

Gundersen Lutheran Medical Center, La Crosse, Wisconsin

University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Froedtert Menomonee Falls Hospital, Menomonee Falls, Wisconsin

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin

Medical College of Wisconsin, Milwaukee, Wisconsin

Aurora Sinai Medical Center, Milwaukee, Wisconsin

Marshfield Medical Center - Minocqua, Minocqua, Wisconsin

ProHealth D N Greenwald Center, Mukwonago, Wisconsin

Cancer Center of Western Wisconsin, New Richmond, Wisconsin

Drexel Town Square Health Center, Oak Creek, Wisconsin

ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin

Aspirus Cancer Care - James Beck Cancer Center, Rhinelander, Wisconsin

Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin

HSHS Saint Nicholas Hospital, Sheboygan, Wisconsin

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin

Aspirus Cancer Care - Stevens Point, Stevens Point, Wisconsin

Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin

Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin

Aurora Medical Center in Summit, Summit, Wisconsin

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin

Aspirus Regional Cancer Center, Wausau, Wisconsin

Aurora West Allis Medical Center, West Allis, Wisconsin

Froedtert West Bend Hospital/Kraemer Cancer Center, West Bend, Wisconsin

Diagnostic and Treatment Center, Weston, Wisconsin

Marshfield Medical Center - Weston, Weston, Wisconsin

Aspirus Cancer Care - Wisconsin Rapids, Wisconsin Rapids, Wisconsin

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta

Cross Cancer Institute, Edmonton, Alberta

BCCA-Abbotsford Cancer Centre, Abbotsford, British Columbia

BCCA-Cancer Centre for the Southern Interior, Kelowna, British Columbia

BCCA-Cancer Centre for the North, Prince George, British Columbia

BCCA-Fraser Valley Cancer Centre, Surrey, British Columbia

BCCA-Vancouver Cancer Centre, Vancouver, British Columbia

BCCA-Vancouver Island Cancer Centre, Victoria, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Atlantic Health Sciences Corporation-Saint John Regional Hospital, Saint John, New Brunswick

Doctor H. Bliss Murphy Cancer Centre, St. John's, Newfoundland and Labrador

QEII Health Sciences Centre/Nova Scotia Health Authority, Halifax, Nova Scotia

Royal Victoria Regional Health Centre, Barrie, Ontario

Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario

Kingston Health Sciences Centre, Kingston, Ontario

Waterloo Regional Health Network, Kitchener, Ontario

London Regional Cancer Program, London, Ontario

Trillium Health Partners - Credit Valley Hospital, Mississauga, Ontario

Ottawa Hospital and Cancer Center-General Campus, Ottawa, Ontario

Niagara Health System-Saint Catharines General, Saint Catharines, Ontario

Algoma District Cancer Program Sault Area Hospital, Sault Ste Marie, Ontario

Health Sciences North, Sudbury, Ontario

Odette Cancer Centre- Sunnybrook Health Sciences Centre, Toronto, Ontario

University Health Network-Princess Margaret Hospital, Toronto, Ontario

CSSS Champlain-Charles Le Moyne, Greenfield Park, Quebec

Hopital de la Cite-de-la-Sante, Laval, Quebec

CIUSSSEMTL-Hopital Maisonneuve-Rosemont, Montreal, Quebec

CHUM - Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec

The Research Institute of the McGill University Health Centre (MUHC), Montreal, Quebec

Jewish General Hospital, Montreal, Quebec

CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ), Quebec City, Quebec

Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec

Allan Blair Cancer Centre, Regina, Saskatchewan

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Conditions: Breast Cancer

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