Music and ABS as a Potential Anxiety Intervention
Recruiting
Anxiety is a growing problem and has been steadily increasing, particularly in the adolescent and young adult populations in the past 24 years. Music and auditory beat stimulation (ABS) in the theta frequency range (4-7 Hz) are sound-based anxiety treatments that have been investigated in prior studies with subjective measures of anxiety. Here, the anxiety-reducing potential of calm music combined with theta ABS will be examined in a large sample of participants with objective psychophysiologica... Read More
Gender:
ALL
Ages:
Between 18 years and 38 years
Trial Updated:
04/15/2025
Locations: Toronto Metropolitan University, Toronto, Ontario
Conditions: Anxiety State
RAPid SimPLE Targeted Radiation Treatment for Brain Metastases
Recruiting
The aim of the study is to show that rapid, simple targeted radiotherapy to brain metastases with 8 Gy / 1 is non-inferior to 20 Gy / 5 in terms of overall survival for patients with poor prognosis.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/15/2025
Locations: BC Cancer - Abbotsford, Abbotsford, British Columbia +5 locations
Conditions: Brain Metastases, Adult
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
Recruiting
This research trial studies biomarkers in tumor tissue samples from patients with newly diagnosed neuroblastoma or ganglioneuroblastoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
Gender:
ALL
Ages:
30 years and below
Trial Updated:
04/14/2025
Locations: Children's Hospital of Alabama, Birmingham, Alabama +258 locations
Conditions: Ganglioneuroblastoma, Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma, Regional Neuroblastoma, Stage 4 Neuroblastoma, Stage 4S Neuroblastoma
Exercise and Cardiac Stunning During HD
Recruiting
The purpose of this study is to determine the effect of a 12-week cycling during hemodialysis program on hemodialysis-induced myocardial stunning in adult individuals receiving hemodialysis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: University of South Australia, Adelaide, South Australia +5 locations
Conditions: End-stage Kidney Disease, Hemodialysis
Physiotherapy Dry Needling Accuracy
Recruiting
The goal of this clinical trial is to learn if the addition of cadaver review improves: * the accuracy of physiotherapists who practice dry needling. * the perceived safety of dry needling by physiotherapists. Researchers will compare the effects of an anatomy review using cadaver material to that of an educational intervention not related to anatomy to see if the anatomy review improves the needling accuracy and safety of physiotherapist who practice dry needling as compared to the control int... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: University of Alberta, Edmonton, Alberta
Conditions: Dry Needling, Physiotherapy
Alberta Chiropractic SelfBack Study
Recruiting
Recurrent and persistent low back pain (LBP) is a massive problem in Canada that causes a substantial pain, disability, cost, and even premature death. The good news is that treatments for recurrent and persistent LBP are available. Many guidelines now recommend education and exercise as the best intervention for chronic LBP. Unfortunately, education and exercise programs are not publicly funded in Canada-only Canadians with extended health benefits can access these programs. As a result, the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: University of Alberta, Edmonton, Alberta
Conditions: Chronic Low-back Pain
Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD
Recruiting
The primary purpose of this study is to evaluate the safety and efficacy of ravulizumab in pediatric participants with Neuromyelitis Optica Spectrum Disorder (NMOSD).
Gender:
ALL
Ages:
All
Trial Updated:
04/14/2025
Locations: Research Site, Washington, District of Columbia +20 locations
Conditions: Neuromyelitis Optica Spectrum Disorder
Electrical Stimulation to Enhance Peripheral Nerve Regeneration
Recruiting
The primary goal of this study is to quantify the functional deficits caused by injuries to the brachial plexus and peripheral nerve in the arm. The second goal is to test the possible benefit of electrical stimulation of the injured nerve following surgery. The investigators will test whether electrical stimulation will improve hand function and nerve regeneration after repair for nerve injury. Injuries causing nerve damage in the arm and hand are common. In severe cases, functional outcomes ev... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: University of Alberta, Edmonton, Alberta
Conditions: Peripheral Nerve Injuries
Impact of Motor Tasks and Lidocaine on Reading Unfamiliar Words in Adults With and Without Dyslexia
Recruiting
Recent claims report that reading ability is partially dependent on speech production. While the evidence for this claim is compelling, it is not known to what extent, the speech production system contributes to successful reading performance in adult populations with dyslexia. One direct way to determine the influence of speech production feedback on reading performance is to measure reading performance in adults with dyslexia with an added motor component (i.e., sucking on a lollipop, holding... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: Department of Communication Sciences and Disorders, University of Alberta, Edmonton, Alberta
Conditions: Reading Disorders
A Good Start Matters Intervention Study
Recruiting
The BC government and partners developed Active Play Standards and a capacity-building strategy to help childcare centers implement the Standards. We have developed an intervention to supplement the governmental capacity-building strategies. The intervention is comprised of implementation support strategies targeted at childcare providers in BC that will aid with the sustainment of Active Play best practices at their facilities. The impact of the intervention will be assessed by measuring its im... Read More
Gender:
ALL
Ages:
30 months and above
Trial Updated:
04/14/2025
Locations: BC Children's Hospital Research Institute, Vancouver, British Columbia
Conditions: Physical Inactivity, Motor Activity
LIVInG With chrONic Cancer TrEatments (LONGEVITI) Study
Recruiting
People with advanced chronic cancers are now living for many years as a result of new targeted anti-cancer treatments. Many of these treatments are quite new and people may take them for months, even years, as long as the treatments are helping. The purpose of this study is to help understand how to best support people receiving these treatments.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
04/14/2025
Locations: Edith Pituskin, Edmonton, Alberta
Conditions: Cancer, Tyrosine Kinase Mutation, Breast Cancer, Melanoma, Multiple Myeloma, Chronic Leukemia, Prostate Cancer, Ovarian Cancer, Colorectal Cancer, Lung Cancer
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
Recruiting
The purpose of this study is to demonstrate the efficacy and evaluate the safety and tolerability of mavorixafor in participants with congenital or acquired primary autoimmune and idiopathic chronic neutropenic disorders who are experiencing recurrent and/or serious infections as assessed by demonstrating its clinical benefit and increasing levels of circulating neutrophils.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
04/14/2025
Locations: Phoenix Children's Hospital, Phoenix, Arizona +79 locations
Conditions: Neutropenia