All Clinical Trials in Canada

A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions

NCT05949684

Recruiting

The purpose of the study is to compare the efficacy and safety of Luspatercept vs epoetin alfa in the treatment of anemia in adults due to IPSS-R very low, low, intermediate-risk MDS in ESA-naïve participants who are non-transfusion dependent (NTD).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Community Cancer Institute, Clovis, California +168 locations

Community Cancer Institute, Clovis, California

Compassionate Cancer Care Medical Group, Fountain Valley, California

Local Institution - 0095, Fresno, California

Cancer and Blood Specialty Clinic, Los Alamitos, California

UCLA Hematology/Oncology - Westwood (Building 200 Suite 120), Los Angeles, California

St. Joseph Hospital, Orange, California

Ventura County Hematology Oncology Specialists, Oxnard, California

John Muir Health - Behring Pavilion, Walnut Creek, California

Local Institution - 0098, Fort Collins, Colorado

Hartford Hospital (HH), Hartford, Connecticut

Yale-New Haven Hospital, New Haven, Connecticut

Halifax Health Medical Center, Daytona Beach, Florida

Local Institution - 0230, Daytona Beach, Florida

Florida Cancer Specialists - South, Fort Myers, Florida

Baptist MD Anderson Cancer Center, Jacksonville, Florida

D&H Cancer Research Center LLC, Margate, Florida

BRCR Global, Plantation, Florida

Florida Cancer Specialists - North, Saint Petersburg, Florida

Advanced Research, Tamarac, Florida

Moffitt Cancer Center, Tampa, Florida

Local Institution - 0240, Honolulu, Hawaii

Northwestern Memorial Hospital, Chicago, Illinois

Orchard Healthcare Research Inc., Skokie, Illinois

Northwest Cancer Centers, P.C., Dyer, Indiana

Local Institution - 0232, Pikeville, Kentucky

Our Lady of the Lake RMC, Baton Rouge, Louisiana

Pontchartrain Cancer Center, Covington, Louisiana

Local Institution - 0097, New Orleans, Louisiana

American Oncology Partners of Maryland, PA, Bethesda, Maryland

Metro-Minnesota Community Clinical Oncology, Saint Louis Park, Minnesota

Hattiesburg Clinic Hematology/Oncology, Hattiesburg, Mississippi

John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey

The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus, Ohio

University of Tennessee Medical Center, Knoxville, Tennessee

University of Texas MD Anderson Cancer Center, Houston, Texas

VCU Health Adult Outpatient Pavillion, Richmond, Virginia

Blue Ridge Cancer Care, Roanoke, Virginia

Kadlec Clinic Hematology and Oncology, Kennewick, Washington

Local Institution - 0213, Seattle, Washington

Centro Medico Barrio Parque, Buenos Aires, Not set

Hospital Británico de Buenos Aires, Buenos Aires, Not set

Instituto Alexander Fleming, Ciudad Autónoma de Buenos Aires, Not set

Blacktown Hospital, Blacktown, New South Wales

Royal Prince Alfred Hospital, Camperdown, New South Wales

Coffs Harbour Health Campus, Coffs Harbour, New South Wales

Pindara Private Hospital, Gold Coast, Queensland

Monash Health, Clayton, Victoria

Austin Health, Heidelberg, Victoria

Hospital Universitario Walter Cantidio, Fortaleza, Ceará

Hospital São Lucas da PUCRS, Porto Alegre, Rio Grande Do Sul

HEMORIO, Rio de Janeiro, Not set

Hospital das Clinicas FMUSP, São Paulo, Not set

Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta

St. Paul's Hospital, Vancouver, British Columbia

Victoria Hospital & Children's Hospital - London Health Sciences Centre, London, Ontario

Sunnybrook Health Sciences Centre, Toronto, Ontario

Enroll SpA, Santiago, Región Metropolitana De Santiago

FALP, Santiago, Región Metropolitana De Santiago

Clínica Inmunocel, Santiago, Región Metropolitana De Santiago

Bradfordhill, Santiago, Región Metropolitana De Santiago

Anhui Provincial Hospital, Hefei, Anhui

Peking University People's Hospital, Beijing, Beijing

Beijing Peking Union Medical College Hospital, Beijing, Beijing

Local Institution - 0223, Chongqing, Chongqing

Local Institution - 0096, Fuzhou Fujian, Fujian

Local Institution - 0220, Xiamen, Fujian

Local Institution - 0031, Guangzhou, Guangdong

The Second Afilliated Hospital of Hebei Medical University, Shijiazhuang, Hebei

The First Hospital of Harbin, Harbin, Heilongjiang

People's Hospital of Henan Province, Zhengzhou, Henan

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei

Xiangya Hospital Central South University, Changsha, Hunan

Jiangsu Province Hospital, Nanjing, Jiangsu

The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu

The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

Local Institution - 0043, Changchun, Jilin

The First Hospital of China Medical University, Shenyang, Liaoning

The Affiliated Hospital of Qingdao University, Qingdao, Shandong

Shanghai Sixth People's Hospital, Shanghai, Shanghai

Shaanxi provincial people's hospital, Xi'an, Shanxi

Local Institution - 0075, Cheng Du, Sichuan

Institute of hematology&blood disease hospital, Tianjin, Tianjin

The first Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang

Local Institution - 0281, Ningbo, Zhejiang

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang

Hospital Pablo Tobon Uribe, Medellin, Antioquia

Sociedad De Oncologia Y Hematologia Del Cesar, Valledupar, Cesar

Fundación Cardiovascular de Colombia, Piedecuesta, Santander

Oncomédica S.A.S, Montería, Not set

Fakultní nemocnice Brno Bohunice, Brno, Brno-město

Fakultni nemocnice Ostrava, Ostrava, Moravskoslezský Kraj

Vseobecna fakultni nemocnice v Praze, Praha 2, Not set

Centre Hospitalier Universitaire de Nice - Hôpital l'Archet, Nice, Alpes-Maritimes

CHU Bordeaux Haut-Leveque, Pessac, Aquitaine

Centre Hospitalier Régional Universitaire de Tours - Hôpital Bretonneau, Tours, Indre-et-Loire

Chu Grenoble Alpes, La Tronche, Isère

Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois, Vandoeuvre lès Nancy, Lorraine

Centre Hospitalier Universitaire d'Angers, Angers, Maine-et-Loire

Gustave Roussy, Villejuif, Val-de-Marne

Hôpital Saint-Louis, Paris, Not set

Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE, Toulouse, Not set

Onkologie Erding, Erding, Bayern

Local Institution - 0250, Kempten, Bayern

Gemeinschaftspraxis für Hämatologie und Onkologie Münster, Münster, Nordrhein-Westfalen

InVO Institut für Versorgungsforschung in der Onkologie, Koblenz, Rheinland-Pfalz

Universitätsklinikum Leipzig, Leipzig, Sachsen

Universitätsklinikum Jena, Jena, Thüringen

Praxis fur Hamatologie und Onkologie, Berlin, Not set

Local Institution - 0028, Berlin, Not set

Universitaetsklinikum Duesseldorf, Düsseldorf, Not set

Local Institution - 0255, Lübeck, Not set

Kliniken Ostalb, Stauferklinikum, Mutlangen, Not set

Gemeinschaftspraxis Dres. med. Björn Schöttker & Dominik Pretscher, Würzburg, Not set

Local Institution - 0242, Patras, Achaḯa

University Hospital of Patras, Patras, Achaḯa

General Hospital of Athens "G. Gennimatas", Athens, Attikí

General Hospital of Athens "Laiko", Athens, Attikí

Attikon General University Hospital, Chaidari, Attikí

University Hospital of Alexandroupolis, Alexandroupolis, Not set

Local Institution - 0034, Hksar, Not set

Heves Vármegyei Markhot Ferenc Oktatókórház és Rendelőintézet, Eger, Heves

Szabolcs Szatmár Bereg Vármegyei Oktatókórház, Nyiregyhaza, Szabolcs-Szatmár-Bereg

Semmelweis Egyetem, Budapest, Not set

All India Institute of Medical Sciences, New Delhi, Delhi

Rajiv Gandhi Cancer Institute And Research Centre, New Delhi, Delhi

Hemato Oncology Clinic, Ahmedabad, Gujarat

Local Institution - 0273, Ahmedabad, Gujarat

Local Institution - 0177, Bengaluru, Karnataka

Institute of Medical Sciences and Sum Hospital, Bhubaneswar, Odisha

Local Institution - 0185, Hyderabad, Not set

Local Institution - 0186, New Delhi, Not set

Fondazione Policlinico Tor Vergata, Rome, Lazio

Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Lombardia

ASST Grande Ospedale Metropolitano Niguarda, Milan, Milano

Humanitas, Rozzano, Milano

Azienda Ospedaliera Ordine Mauriziano di Torino, Torino, Piemonte

Azienda Ospedaliera Universitaria Careggi, Firenze, Toscana

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola, Bologna, Not set

Grande Ospedale Metropolitano - Presidio Morelli, Reggio Calabria, Not set

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore, Roma, Not set

Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Roma, Verona, Not set

Local Institution - 0123, Kitakyushu-shi, Fukuoka

Local Institution - 0117, Sapporo, Hokkaido

Local Institution - 0126, Amagasaki, Hyogo

Local Institution - 0120, Sagamihara, Kanagawa

Local Institution - 0118, Sendai-shi, Miyagi

Local Institution - 0125, Osaka-sayama, Osaka

Local Institution - 0121, Shimotsuga, Tochigi

Local Institution - 0124, Nagasaki, Not set

Local Institution - 0122, Osaka, Not set

Local Institution - 0119, Tokyo, Not set

Centro de Investigacion Clinica de Oaxaca, Oaxaca de Juarez, Oaxaca

Hematológica Alta Especialidad SC, consultorio 830, Huixquilucan, Not set

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Not set

Unidad Médica Onco-hematológica, Puebla, Not set

Specjalistyczny Szpital im. dra Alfreda Sokołowskiego w Wałbrzychu, Wałbrzych, Dolnośląskie

Uniwersyteckie Centrum Kliniczne, Gdańsk, Not set

Pratia Onkologia Katowice, Katowice, Not set

MTZ Clinical Research powered by Pratia, Warsaw, Not set

Auxilio Mutuo Cancer Center, San Juan, Not set

Local Institution - 0237, San Juan, Not set

Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]

Institut Català d'Oncologia - L'Hospitalet, L'Hospitalet de Llobregat, Catalunya [Cataluña]

Hospital Clinico de Valencia, Valencia, Valenciana, Comunitat

Hospital Universitario Virgen Nieves, Granada, Not set

Hospital La Princesa, Madrid, Not set

Hospital Universitario Central de Asturias, Oviedo, Not set

Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca, Salamanca, Not set

Hospital Universitario Virgen Del Rocio, Sevilla, Not set

Conditions: Myelodysplastic Syndromes

Learn More ›

IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma

NCT05987332

Recruiting

This is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotinib or investigator's choice of treatment (pembrolizumab, ipilimumab + nivolumab, or dacarbazine).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Honor Health, Scottsdale, Arizona +66 locations

Honor Health, Scottsdale, Arizona

Moores Cancer Center, La Jolla, California

UCLA Medical Center, Los Angeles, California

The Angeles Clinic and Research Institute, Los Angeles, California

California Pacific Medical Center (CPMC), San Francisco, California

University of California San Francisco, San Francisco, California

University of Colorado Cancer Center, Aurora, Colorado

SCRI at HealthONE, Denver, Colorado

University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida

Moffitt Cancer Center, Tampa, Florida

Northside Hospital Atlanta, Atlanta, Georgia

University of Iowa, Iowa City, Iowa

Massachusetts General Hospital, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

The Cancer and Hematology Centers, Grand Rapids, Michigan

Minnesota Oncology Hematology, P.A., Burnsville, Minnesota

Mayo Clinic, Rochester, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Roswell Park Cancer Institute, Buffalo, New York

Northwell Health, Manhasset, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Duke University Health System, Durham, North Carolina

University of Cincinnati, Cincinnati, Ohio

The Cleveland Clinic Foundation, Cleveland, Ohio

Thomas Jefferson University, Philadelphia, Pennsylvania

University of Pittsburgh Medical Center, Pittsburg, Pennsylvania

SCRI Oncology Partners, Nashville, Tennessee

Texas Oncology- DFW, Dallas, Texas

UT Southwestern Medical Center, Dallas, Texas

Houston Methodist Cancer Center, Houston, Texas

MD Anderson Cancer Center, Houston, Texas

Westmead Hospital, Sydney, New South Wales

Princess Alexander Hospital, Brisbane, Queensland

Peter MacCallum Cancer Centre, Melbourne, Victoria

Alfred Health, Melbourne, Victoria

Sir Charles Gairdner Hospital, Perth, Washington

Queen Elizabeth Hospital, Adelaide, Not set

Cliniques Universitaires Saint Luc, Brussels, Not set

Cross Cancer Institute, University of Alberta, Edmonton, Alberta

BC Cancer Agency, Vancouver, British Columbia

Princess Margaret Cancer Centre, Toronto, Ontario

Centre Hospitalier de l'Universite de Montreal- CHUM, Montréal, Quebec

The Leon Berard Center, Lyon, Not set

Institut Curie, Paris, Not set

NCT Heidelberg, Heidelberg, Baden- Württemberg

Universitätsklinikum Essen (AöR), Essen, North Rhine-Westphalia

Universitätsklinikum Köln, Köln, North Rhine-Westphalia

Universitätsklinikum Carl Gustav Carus Dresden, Dresden, Saxony

Charité - Universitätsmedizin Berlin, Berlin, Not set

Hadassah Medical Center, Jerusalem, Not set

Sheba Medical Center, Ramat-Gan, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Not set

Istituto Nazionale dei Tumori Fondazione Pascale, Napoli, Not set

Fondazione Policlinico Gemelli IRCCS, Roma, Not set

AOUS Policlinico Le Scotte, Siena, Not set

LUMC (Leids Universitair Medisch Centrum), Leiden, Not set

Ośrodek Badań Klinicznych Wczesnych Faz, Uniwersyteckie Centrum Kliniczne w Gdańsku, Gdańsk, Not set

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie Państwowy Instytut Badawczy, Warsaw, Not set

Catalan Institute of Oncology, L'Hospitalet de Llobregat, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

Hospital General Universitario Valencia, Valencia, Not set

Dermatologische Klinik, USZ Flughafen Geschoss 7 - Klinische Forschung, Zuerich, Not set

The Beatson West of Scotland Cancer Centre, Glasgow, Not set

Mount Vernon Cancer Centre East & North Herts NHS Trust, Northwood, Not set

The Clatterbridge Cancer Centre NHS Foundation Trust, Wirral, Not set

Conditions: Metastatic Uveal Melanoma

Learn More ›

PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

NCT06855329

Recruiting

This is a prospective, observational cohort study. Participants with non-idiopatic pulmonary fibrosis, interstitial lung disease (ILD) will be followed for 24 months to systematically collect clinical, imaging, and biospecimen data. The primary objective is to optimize progressive pulmonary fibrosis (PPF) classification and establish PPF incidence for key ILD subtypes. Additional exploratory objectives are to 1) Prospectively validate a novel PPF classifier and assess performance durability over... Read More

Gender:

ALL

Ages:

Between 18 years and 80 years

Trial Updated:

08/18/2025

Locations: University of Massachusetts Chan Medical School, Worcester, Massachusetts +12 locations

Conditions: Progressive Pulmonary Fibrosis, Interstitial Lung Disease

Learn More ›

VY7523-102: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascending Dose Study in Participants With Early Alzheimer's Disease

NCT06874621

Recruiting

This study is to be conducted in participants with early Alzheimer's Disease to test VY7523, a new drug being researched for treatment of Alzheimer's Disease. This study will look at how safe the drug is and how it works in the brain. It was first tested in normal, healthy participants who volunteered to participate. The study will look at three different dose levels, starting with the lowest dose first and moving to higher doses and more participants after safety has been reviewed by doctors an... Read More

Gender:

ALL

Ages:

Between 50 years and 90 years

Trial Updated:

08/18/2025

Locations: VYGR Site 840018, Los Angeles, California +22 locations

Conditions: Alzheimer's Disease (AD)

Learn More ›

ORKA-001 Versus Placebo in Patients With Moderate-to-Severe Plaque Psoriasis

NCT07090330

Recruiting

This is a multicenter, randomized, double-blinded, placebo-controlled, proof-of-concept study to evaluate the efficacy, safety, tolerability, and pharmacokinetics of ORKA-001 in adult participants with moderate-to-severe plaque psoriasis.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Oruka Therapeutics Investigative Site, Fountain Valley, California +15 locations

Conditions: Plaque Psoriasis

Learn More ›

BoneTape Feasibility Trial

NCT06600854

Recruiting

This study aims to evaluate the safety, effectiveness, and usability of BoneTape, an innovative medical device designed to fix facial bone fractures, specifically in the zygomaticomaxillary (midface) region. Zygomaticomaxillary fractures, often caused by trauma like car accidents or falls, require surgery to align and stabilize the bones for proper healing. Traditional methods use metal plates and screws, which can be complicated to install, over-engineered for the area, and may lead to complications, requiring additional surgeries. BoneTape is a new, resorbable (biodegradable) device that offers a simpler, potentially safer alternative. Unlike traditional metal hardware, BoneTape is a flexible, thin plate that can be easily cut to the required shape during surgery and applied directly to the bone using a special tool that anchors it without needing to drill or screw holes. This process significantly simplifies the surgical procedure, reduces the time needed for fixation, and avoids complications associated with drilling into healthy bone tissue. Study Objectives: Feasibility: Determine if BoneTape can be successfully used to stabilize midfacial fractures. Effectiveness: Assess the ability of BoneTape to help bones heal properly without additional complications. Safety: Monitor and evaluate any adverse events related to the use of BoneTape. Study Design: The study is designed as a single-arm, cohort study. Participants will undergo baseline pre-operative assessments, including clinical exams, CT scans, and pain questionnaires. BoneTape will be applied during surgery, and post-operative assessments will take place within 24 hours. Follow-up visits will occur at 1 week, 6 weeks, 24 weeks, and 12 months to monitor the healing process, assess pain levels, and check for any adverse events. Eligibility Criteria: Inclusion: Adults with a unilateral, non-comminuted (not broken into multiple pieces) zygomaticomaxillary fracture requiring surgery. Must be skeletally mature, able and willing to attend follow-up visits, and provide informed consent. Exclusion: Patients with critically sized bone defects, fractures requiring orbital floor surgery, pregnancy, certain medical conditions impairing bone healing, or those unwilling or unable to follow the study procedures. Study Duration: The total study duration is expected to be 21-24 months, including the 12-month follow-up period for each participant. Outcome Measures: The primary outcomes include the feasibility of the procedure (successful use of BoneTape without additional hardware), early effectiveness (bone healing and stability at 6 and 24 weeks), and safety (rate and type of adverse events up to 24 weeks). Secondary outcomes will assess long-term safety and effectiveness at 12 months, patient-reported outcomes on pain, and physician feedback on device usability. This study is a critical step in evaluating BoneTape as a potential alternative to current facial bone fixation methods, potentially improving surgical outcomes and patient quality of life by reducing the complexity of procedures and minimizing the need for additional surgeries. Read Less

Gender:

ALL

Ages:

All

Trial Updated:

08/18/2025

Locations: Sunnybrook Health Sciences Centre, Toronto, Ontario

Conditions: Zygomaticomaxillary Complex Fracture, Zygomatic Fractures, Zygoma Fracture

Learn More ›

rTMS for Youth Inpatients With Depression

NCT07140575

Recruiting

Youth aged 15-24 are likelier to have depression than all age groups in Canada. One-third of depressed youth do not respond to psychotherapy and/or antidepressant medications. A treatment called repetitive transcranial magnetic stimulation or rTMS has proven helpful in adolescents and young adults whose depressive symptoms have been difficult to treat with psychotherapy and/or antidepressants. Unfortunately, youth find rTMS difficult to access because it is not funded by the Ontario Health Insur... Read More

Gender:

ALL

Ages:

Between 14 years and 19 years

Trial Updated:

08/18/2025

Locations: Sunnybrook Health Sciences Centre, Toronto, Ontario

Conditions: Major Depression Moderate, Feasibility Studies

Learn More ›

A Phase III Trial Comparing Tisagenlecleucel to Standard of Care (SoC) in Adult Participants With r/r Follicular Lymphoma

NCT05888493

Recruiting

This trial will compare tisagenlecleucel to standard of care in adult participants with relapsed or refractory (r/r) follicular lymphoma.

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

08/18/2025

Locations: TRIHEALTH Good Samarithan Hospital, Cincinnati, Ohio +35 locations

TRIHEALTH Good Samarithan Hospital, Cincinnati, Ohio

VA Tennessee Valley Healthcare System, Nashville, Tennessee

Novartis Investigative Site, Camperdown, New South Wales

Novartis Investigative Site, Clayton, Victoria

Novartis Investigative Site, Melbourne, Victoria

Novartis Investigative Site, Nedlands, Western Australia

Novartis Investigative Site, Linz, Not set

Novartis Investigative Site, Salzburg, Not set

Novartis Investigative Site, Toronto, Ontario

Novartis Investigative Site, Montreal, Quebec

Novartis Investigative Site, Ostrava, Poruba

Novartis Investigative Site, Budapest, Not set

Novartis Investigative Site, Seoul, Not set

Novartis Investigative Site, Gliwice, Slaskie

Novartis Investigative Site, Poznan, Wielkopolskie

Novartis Investigative Site, Gdansk, Not set

Novartis Investigative Site, Lodz, Not set

Novartis Investigative Site, Bucharest, Not set

Novartis Investigative Site, Singapore, Not set

Novartis Investigative Site, Bratislava, Not set

Novartis Investigative Site, Hospitalet de LLobregat, Barcelona

Novartis Investigative Site, Santander, Cantabria

Novartis Investigative Site, Salamanca, Castilla Y Leon

Novartis Investigative Site, Barcelona, Catalunya

Novartis Investigative Site, Santiago De Compostela, Galicia

Novartis Investigative Site, El Palmar, Murcia

Novartis Investigative Site, Barcelona, Not set

Novartis Investigative Site, Cordoba, Not set

Novartis Investigative Site, Madrid, Not set

Novartis Investigative Site, Kaohsiung, Not set

Novartis Investigative Site, Taichung, Not set

Novartis Investigative Site, Taipei, Not set

Conditions: Follicular Lymphoma (FL)

Learn More ›

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

NCT06697301

Recruiting

The study is for patients with advanced melanoma who are eligible for standard therapy with Pembrolizumab.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Ironwood Cancer & Research Centers, Chandler, Arizona +56 locations

Ironwood Cancer & Research Centers, Chandler, Arizona

The Oncology Institution of Hope and Innovation, Los Angeles, California

Providence Medical Foundation, Santa Rosa, California

UCHealth Memorial Hospital Central, Colorado Springs, Colorado

Bioresearch Partner, Hialeah, Florida

Washington University School of Medicine in St. Louis, Saint Louis, Missouri

Gabrail Cancer Center Research LLC, Canton, Ohio

University of Pittsburgh Medical Center(UPMC)-Hillman Cancer Center, Pittsburgh, Pennsylvania

Cancer Care Wollongong, Wollongong, New South Wales

Icon Cancer Centre Chermside, Chermside, Queensland

Southern Adelaide Local Health Network Incorporated Flinders Medical Centre, Bedford Park, South Australia

Eastern Health, Box Hill, Victoria

Universitätsklinikum Graz, Graz, Styria

Universitair Ziekenhuis Antwerpen, Edegem, Antwerpen

Centre Hospitalier Universitaire Universite Catholique de Louvain - Site Godinne, Yvoir, Namur

Universitair Ziekenhuis Leuven - Campus Gasthuisberg, Leuven, Vlaams Brabant

Algemeen Ziekenhuis Groeninge - Campus Kennedylaan, Kortrijk, West-Vlaanderen

Cliniques Universitaires Saint-Luc, Brussels, Not set

Sunnybrook Research Ins<tute, Toronto, Ontario

Masaryk Memorial Cancer Institute, Brno, Not set

Aarhus Universitetshospital, Aarhus, Midtjylland

Aalborg University Hospital, Aalborg, Nord Jutland

Oulu University Hospital, Oulu, Not set

Centre Hospitalier Universitaire Grenoble Alpes, La Tronche, Isère

Centre Hospitalier Lyon-Sud, Pierre-Bénite, Rhone-Alpes

CHU Rouen, Rouen, Not set

Universitätsmedizin Mannheim, Mannheim, Baden-Württemberg

Universitätsklinikum Tübingen, Tübingen, Baden-Württemberg

Universitat Leipzig, Saxony, Leipzig

Elbe Kliniken Stade-Buxtehude, Buxtehude, Lower Saxony

Johannes Wesling Klinikum Minden, Minden, Nordrhein-Westfalen

University of Mainz Medical Center, Mainz, RLP

Universitätsklinikum Schleswig-Holstein - Campus Kiel, Kiel, Schleswig-Holstein

Universitätsklinikum Schleswig-Holstein - Campus Lübeck, Lübeck, Schleswig-Holstein

Soroka medical center, Be'er Sheva, Not set

Rabin Medical Center, Petach Tikva, Not set

Ella Lemelbaum Institute for Immuno-Oncology and Melanoma, Ramat Gan, Not set

Tel Aviv Medical Center, Tel Aviv, Not set

Auckland City Hospital, Auckland, Not set

Christchurch Public Hospital, Christchurch, Not set

Oslo University Hospital - The Norwegian Radium Hospital, Oslo, Not set

Hospital da Luz Lisboa, Lisboa, Not set

Cancercare Port Elizabeth - Langenhoven Drive Oncology Centre, Port Elizabeth, Eastern Cape

The Medical Oncology Centre of Rosebank, Saxonwold, Gauteng

Cape Town Oncology Trials, Cape Town, Western Cape

TASK Eden, George Central, Western Cape

Hospital Universitari Dexeus, Barcelona, Not set

Vall d' Hebron Institute of Oncology, Barcelona, Not set

Institut Català d'Oncologia Girona (ICO Girona), Girona, Not set

GenesisCare Madrid - Hospital San Francisco de Asís, Madrid, Not set

Hospital Universitario Virgen de la Victoria, Málaga, Not set

IVO - Fundacion Instituto Valenciano de Oncologia, Valencia, Not set

INCLIVA Instituto de Investigación Sanitaria, Valencia, Not set

Gävle Sjukhus, Gävle, Gävleborgs Län

Universitätsspital Zürich, Zürich, Not set

Guy's and St Thomas' NHS Foundation Trust, London, England

Sarah Cannon Research Institute London, London, England

Conditions: Advanced Melanoma

Learn More ›

Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

NCT06408935

Recruiting

The purpose of this study is to evaluate the efficacy of guselkumab in healing of all layers of the digestive tract (transmural healing) with the help of a score called Magnetic Resonance Index of Activity (MaRIA) based on a scan at Week 48.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/18/2025

Locations: Center for Colitis and Crohns Disease University of California, San Francisco, California +72 locations

Center for Colitis and Crohns Disease University of California, San Francisco, California

Washington University School Of Medicine, Saint Louis, Missouri

Medical University of South Carolina, Charleston, South Carolina

The Queen Elizabeth Hospital, Adelaide, Not set

Concord Repatriation General Hospital, Concord, Not set

Northern Hospital, Melbourne, Not set

Fiona Stanley Hospital, Murdoch, Not set

Mater Hospital Brisbane, South Brisbane, Not set

Cliged, Macae, Not set

Instituto Mederi de Pesquisa e Saude, Passo Fundo, Not set

NPCRS Nucleo de Pesquisa Clinica do Rio Grande do Sul, Porto Alegre, Not set

INTEGRAL Pesquisa e Ensino, Votuporanga, Not set

Foothills Hospital, Calgary, Alberta

Western University & London Health Sciences Centre, London, Ontario

Hopital du Sacre-Coeur de Montreal, Montreal, Quebec

Nemocnice Ceske Budejovice a s, Ceske Budejovice, Not set

Hepato-gastroenterologie HK, s.r.o., Hradec Kralove, Not set

ISCARE a.s., Praha 9, Not set

APHP - Hopital Bichat - Claude Bernard, Paris, Not set

Klinikum Augsburg, Augsburg, Not set

Charite Universitaetsmedizin Berlin, Berlin, Not set

Praxis Fur Gastroenteroligie, Berlin, Not set

Medizinisches Versorgungszentrum (MVZ) Dachau, Dachau, Not set

Universitatsklinikum Frankfurt/ Medizinische Klinik 1, Frankfurt, Not set

Universitatsmedizin Gottingen, Gottingen, Not set

BSF Studiengesellschaft, Halle, Not set

Medizinische Hochschule Hannover, Hannover, Not set

Universitatsklinikum Schleswig Holstein, Kiel, Not set

Staedtisches Klinikum Lueneburg, Luneburg, Not set

MVZ Portal 10, Munster, Not set

Siloah St Trudpert Klinikum, Pforzheim, Not set

Universitaetsklinikum Ulm, Ulm, Not set

Rambam Medical Center, Haifa, Not set

The Edith Wolfson Medical Center, Holon, Not set

Hadassah Medical Organization, Jerusalem, Not set

Galilee Medical Center, Nahariya, Not set

Rabin Medical Center, Petah Tikva, Not set

The Chaim Sheba Medical Center, Ramat Gan, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

Azienda Ospedaliera Policlinico S. Orsola-Malpighi, Bologna, Not set

IRCCS Ospedale San Raffaele, Milano, Not set

Universita Di Napoli Federico Ii, Napoli, Not set

Asst Rhodense - Ospedale Di Rho, Rho, Not set

Universita Campus Bio-Medico di Roma, Roma, Not set

Fondazione Policlinico Tor Vergata, Roma, Not set

Fondazione Policlinico Universitario A Gemelli IRCCS, Roma, Not set

IRCCS Humanitas Rozzano-IBD Center Malattie Infiammatorie Croniche Intestinali, Rozzano, Not set

IRCCS Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo, Not set

NZOZ Centrum Medyczne KERmed, Bydgoszcz, Not set

Centrum Medyczne Medyk, Rzeszow, Not set

GASTROMED Sp. z o.o., Torun, Not set

WIP Warsaw IBD Point Profesor Kierkus, Warszawa, Not set

Melita Medical Sp. z o.o., Wroclaw, Not set

Centrum Medyczne Oporow, Wroclaw, Not set

EuroMediCare Szpital Specjalistyczny z Przychodnia, Wroclaw, Not set

ETG Zamosc, Zamosc, Not set

FNsP F.D.R. Banska Bystrica, Banska Bystrica, Not set

Cliniq s.r.o., Bratislava, Not set

ENDOMED s.r.o, Kosice, Not set

KM Management spol. s r.o., Nitra, Not set

GASTRO I. s.r.o., Presov, Not set

Hosp. Gral. Univ. Dr. Balmis, Alicante, Not set

Hosp Reina Sofia, Cordoba, Not set

Complejo Hosp Univ. de Ferrol, Ferrol, Not set

Hosp. Univ. de La Paz, Ferrol, Not set

Hosp. Univ. de La Princesa, Madrid, Not set

Hosp. Univ. Pta. de Hierro Majadahonda, Madrid, Not set

Hosp. Clinico Univ. de Valencia, Valencia, Not set

Hosp. Alvaro Cunqueiro, Vigo, Not set

Chang-Hua Christian Hospital, Changhua, Not set

Far Eastern Memorial Hospital, New Taipei, Not set

National Taiwan University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Conditions: Crohn's Disease

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Effect of Music on Surgical Performance During Artificial Intelligence-Based Simulation Training

NCT07111481

Recruiting

At the Neurosurgical Simulation and Artificial Intelligence Learning Centre, we seek to provide surgical trainees with innovative technologies that allow them to improve their surgical technical skills in risk-free environments, potentially improving patient operative outcomes. The Intelligent Continuous Expertise Monitoring System (ICEMS), a deep learning application that assesses and trains neurosurgical technical skill and provides continuous intraoperative feedback, is one such technology th... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/17/2025

Locations: Neurosurgical Simulation and Artificial Intelligence Learning Centre, Montreal, Quebec

Conditions: Surgical Education

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Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

NCT05947955

Recruiting

BTI-203 is a randomized, double-blind, placebo-controlled, multicenter, Phase 2 proof-of-concept (POC) study to evaluate the efficacy and safety of rhu-pGSN plus standard of care (SOC) in subjects with moderate-to-severe ARDS (P/F ratio ≤150) due to pneumonia or other infections. Potential subjects hospitalized with pneumonia or other infections are to be screened within 24 hours of diagnosis of ARDS.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/17/2025

Locations: University of California Irvine Medical Center, Irvine, California +66 locations

University of California Irvine Medical Center, Irvine, California

Cedars-Sinai Medical Center, Los Angeles, California

Wellstar MCG Augusta University, Augusta, Georgia

Northwestern University - Pulmonary and Critical Care Medicine, Chicago, Illinois

University of Louisville Hospital - Jewish Hospital, Louisville, Kentucky

University of Louisville-Jewish Hospital, Louisville, Kentucky

Mayo Clinic, Rochester, Minnesota

Hannibal Regional Hospital, Hannibal, Missouri

Bryan Medical Center, Lincoln, Nebraska

Penn State Health - Milton S. Hershey Medical Center, Hershey, Pennsylvania

McGovern Medical School - UT Physicians Pulmonary Medicine - Texas Medical Center, Houston, Texas

Baylor Scott & White Health, Temple, Texas

HUB - Hôpital Erasme, Brussels, Not set

CHU Charleroi Marie Curie Hospital, Charleroi, Not set

Centre Hospitalier Regional de la Citadelle, Liege, Not set

Clinique Saint-Pierre Ottignies, Ottignies, Not set

Acibadem City Clinic UMHAT Tokuda - Sofia, Sofia, Not set

Military Medical Academy, Sofia, Not set

UMHAT "Alexandrovska" EAD, Sofia, Not set

Foothills Medical Centre, Calgary, Alberta

Royal Alexandra Hospital, Edmonton, Alberta

Lions Gate Hospital, North Vancouver, British Columbia

University Health Network (UHN)-Toronto General Hospital (TGH), Toronto, Ontario

McGill University Health Centre - Royal Victoria Hospital (MUHC-RVH), Montreal, Quebec

Centre intégré universitaire de santé et services sociaux du nord de l'île de Montréal-Hôpital du Sacré de Montréal (CIUSSS-NÎM-HSCM), Montreal, Quebec

Peter Lougheed Centre, Calgary, Not set

Rocky View General Hospital, Calgary, Not set

South Health Campus, Calgary, Not set

St. Anne's University Hospital, Brno, Not set

University Hospital Královské Vinohrady, Prague, Not set

General University Hospital, Prague, Not set

Centre Hospitalier Departemental (CHD) Vendee, La Roche-sur-Yon, Not set

Hôpital du Kremlin Bicêtre, APHP, Le Kremlin Bicêtre, Not set

Centre Hospitalier de Melun-Senart, Melun, Not set

CHU Nantes, Nantes, Not set

Centre Hospitalier Lyon Sud, Oullins-Pierre-Bénite, Not set

Tenon Hospital, Paris, Not set

Nouvel Hopital Civil, Strasbourg, Not set

Saarland University Hospital, Homburg, Not set

Jena University Hospital, Jena, Not set

University Hospital LMU Munich, Munich, Not set

National Institute of Pulmonology, Budapest, Not set

Petz Aladár University Teaching Hospital, Gyor, Not set

Szent Damján Greek Catholic Hospital, Kisvarda, Not set

Szabolcs-Szatmar-Bereg County Teaching Hospital, Andras Josa Hospital, Nyiregyhaza, Not set

Hospital of Siofok, Siófok, Not set

Teaching Hospital of Vas County, Szombathely, Not set

Ferenc Csolnoky Hospital of Veszprem County, Veszprém, Not set

Asst-Spedali Civili di Brescia, Brescia, Not set

Fondazione Policlinico A. Gemelli IRCCS, Rome, Not set

Jeroen Bosch Ziekenhuis, 's-Hertogenbosch, Not set

Gelre Hospitals, Department of ICU, Apeldoorn, Not set

Gelderse Vallei Hospital, Ede, Not set

Medisch Spectrum Twente, Enschede, Not set

Canisius Wilhelmina Ziekenhuis, Nijmegen, Not set

Spital Universitar de Urgenta ELIAS (University Emergency Hospital Elias), Bucharest, Not set

County Clinical Hospital Tirgu Mures, Targu Mures, Not set

Clinical County Hospital Timisoara, Timisoara, Not set

Hospital Clínic Barcelona, Barcelona, Not set

Bellvitge University Hospital, Barcelona, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario de Getafe, Madrid, Not set

Clínico San Carlos, Madrid, Not set

Hospital Universitari de Tarragona Joan XXIII, Tarragona, Not set

University Hospital of Wales, Cardiff, Not set

Derriford Hospital (University Hospitals Plymouth Hospital Trust), Plymouth, Not set

Pinderfields Hospital (Mid Yorkshire Teaching NHS Trust), Wakefield, Not set

Conditions: Acute Respiratory Distress Syndrome, Infections

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